Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells

Chemical Research in Toxicology

Volumn 28, Issue 5, 2015, Pages 855-871

  McLean, Lancelot S ^a   Watkins, Cheri N ^b   Campbell, Petreena ^b   Zylstra, Dain ^a   Rowland, Leah ^b   Amis, Louisa H ^b   Scott, Lia ^b   Babb, Crystal E ^b   Livingston, W Joel ^b   Darwanto, Agus ^b,d   Davis, Willie L ^a,b   Senthil, Maheswari ^b   Sowers, Lawrence C ^c   Brantley, Eileen ^a,b  

^a LOMA LINDA UNIVERSITY HEALTH   (United States)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

^d Department of Surgery School of Medicine Loma Linda University Health ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,6 BENZO[A]PYRENE QUINONE; 2 (4 AMINO 3 METHYLPHENYL) 5 FLUOROBENZOTHIAZOLE; ACETYLCYSTEINE; ALPHA NAPHTHOFLAVONE; ANTINEOPLASTIC AGENT; AROMATIC HYDROCARBON RECEPTOR; BENZO[A]PYRENE; DECITABINE; DOXORUBICIN; MITOGEN ACTIVATED PROTEIN KINASE P38; QUINONE DERIVATIVE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; 2-(4-AMINO-3-METHYLPHENYL)-5-FLUOROBENZOTHIAZOLE; THIAZOLE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER CELL LINE; CANCER INHIBITION; COMET ASSAY; CONTROLLED STUDY; CYTOGLOBIN GENE; CYTOTOXICITY; DNA DAMAGE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; SINGLE STRANDED DNA BREAK; TUMOR SUPPRESSOR GENE; BREAST; BREAST NEOPLASMS; DRUG EFFECTS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; MCF-7 CELL LINE; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA DAMAGE; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MCF-7 CELLS; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REACTIVE OXYGEN SPECIES; RECEPTORS, ARYL HYDROCARBON; THIAZOLES;

EID: 84929397983     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx500485v     Document Type: Article

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