Antitumour 2-(4-aminophenyl)benzothiazoles generate DNA adducts in sensitive tumour cells in vitro and in vivo

British Journal of Cancer

Volumn 88, Issue 3, 2003, Pages 470-477

  Leong, C O ^a   Gaskell, M ^b   Martin, E A ^b   Heydon, R T ^b   Farmer, P B ^b   Bibby, M C ^c   Cooper, P A ^c   Double, J A ^c   Bradshaw, T D ^a   Stevens, M F G ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

2 (4 Aminophenyl)benzothiazole; Breast cancer; DNA adducts; Ovarian cancer; Phortress

Indexed keywords

2 (4 AMINO 3 METHYLPHENYL) 5 FLUOROBENZOTHIAZOLE; 2 (4 AMINO 3 METHYLPHENYL)BENZOTHIAZOLE; 5 FLUORO 2 (4 LYSYLAMINO 3 METHYLPHENYL)BENZOTHIAZOLE; 5F 203; ANTINEOPLASTIC AGENT; BENZOTHIAZOLE DERIVATIVE; CYTOCHROME P450 1A1; DNA; NSC 703786; NSC 710305; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOMA; CANCER CELL; CANCER CELL CULTURE; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DRUG SENSITIVITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OVARY CARCINOMA; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; BENZOTHIAZOLES; DISEASE MODELS, ANIMAL; DNA ADDUCTS; HUMANS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; THIAZOLES; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0037428819     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600719     Document Type: Article

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