The p38 MAPK Pathway is Required for Cell Growth Inhibition of Human Breast Cancer Cells in Response to Activin

Journal of Biological Chemistry

Volumn 276, Issue 21, 2001, Pages 18430-18436

  Cocolakis, Eftihia ^b   Lemay, Serge ^b   Ali, Suhad ^b   Lebrun, Jean Jacques ^a  

^a ROYAL VICTORIA HOSPITAL   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; ENZYME KINETICS; GROWTH KINETICS; PROTEINS; TISSUE CULTURE; TUMORS;

PHOSPHORYLATION;

BIOCHEMISTRY;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 NITROPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACTIVATING TRANSCRIPTION FACTOR 2; ACTIVIN; DNA BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; SMAD PROTEIN; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; INHIBIN; MITOGEN ACTIVATED PROTEIN KINASE P38;

ARTICLE; BREAST CANCER; CANCER INHIBITION; CELL SPECIFICITY; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; TARGET ORGAN; BREAST TUMOR; CELL CULTURE; CELL DIVISION; DRUG EFFECT; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ACTIVINS; BREAST NEOPLASMS; CELL DIVISION; FEMALE; HUMANS; INHIBINS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED;

EID: 0035947728     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010768200     Document Type: Article

References (55)

1. Mathews, L. S., and Vale, W. W. (1993) J. Biol. Chem. 268, 19013-19018
2. Wrana, J. L., Attisano, L., Wieser, R., Ventura, F., and Massague, J. (1994) Nature 370, 341-347
3. Willis, S. A., Zimmerman, C. M., Li, L. I., and Mathews, L. S. (1996) Mol. Endocrinol. 10, 367-379
4. Attisano, L., Wrana, J. L., Montalvo, E., and Massague, J. (1996) Mol. Cell. Biol. 16, 1066-1073
5. Baker, J. C., and Harland, R. M. (1996) Genes Dev. 10, 1880-1889
6. Chen, Y., Lebrun, J. J., and Vale, W. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 12992-12997
7. Zhang, Y., Feng, X., We, R., and Derynek, R. (1996) Nature 383, 168-172
8. Lebrun, J. J., Takabe, K., Chen, Y., and Vale, W. (1999) Mol. Endocrinol. 13, 15-23
9. Lagna, G., Hata, A., Hemmati-Brivanlou, A., and Massague, J. (1996) Nature 383, 832-836
10. Macias-Silva, M., Abdollah, S., Hoodless, P. A., Pirone, R., Attisano, L., and Wrana, J. L. (1996) Cell 87, 1215-1224
11. Nakao, A., Imamura, T., Souchelnytskyi, S., Kawabata, M., Ishisaki, A., Oeda, E., Tamaki, K., Hanai, J., Heldin, C. H., Miyazono, K., and ten Dijke, P. (1997) EMBO J. 16, 5353-5362
12. Zawel, L., Dai, J. L., Buckhaults, P., Zhou, S., Kinzler, K. W., Vogelstein, B., and Kern, S. E. (1998) Mol. Cell 1, 611-617
13. Shi, Y., Wang, Y. F., Jayaraman, L., Yang, H., Massague, J., and Pavletich, N. P. (1998) Cell 94, 585-594
14. Chen, X., Weisberg, E., Fridmacher, V., Watanabe, M., Naco, G., and Whitman, M. (1997) Nature 389, 85-89
15. Labbe, E., Silvestri, C., Hoodless, P. A., Wrana, J. L., and Attisano, L. (1998) Mol. Cell 2, 109-120
16. Hua, X., Liu, X., Ansari, D. O., and Lodish, H. F. (1998) Genes Dev. 12, 3084-3095
17. Zhang, Y., Feng, X. H., and Derynck, R. (1998) Nature 394, 909-913
18. Moustakas, A., and Kardassis, D. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6733-6738
19. Nakashima, K., Yanagisawa, M., Arakawa, H., Kimura, N., Hisatsune, T., Kawabata, M., Miyazono, K., and Taga, T. (1999) Science 284, 479-482
20. Kurokawa, M., Mitani, K., Irie, K., Matsuyama, T., Takahashi, T., Chiba, S., Yazaki, Y., Matsumoto, K., and Hirai, H. (1998) Nature 394, 92-96
21. Sano, Y., Harada, J., Tashiro, S., Gotoh-Mandeville, R., Maekawa, T., and Ishii, S. (1999) J. Biol. Chem. 274, 8949-8957
22. Yamaguchi, K., Shirakabe, K., Shibuya, H., Irie, K., Oishi, I., Ueno, N., Taniguchi, T., Nishida, E., and Matsumoto, K. (1995) Science 270, 2008-2011
23. Hanafusa, H., Ninomiya-Tsuji, J., Masuyama, N., Nishita, M., Fujisawa, J., Shibuya, H., Matsumoto, K., and Nishida, E. (1999) J. Biol. Chem. 274, 27161-27167
24. Sovak, M. A., Arsura, M., Zanieski, G., Kavanagh, K. T., and Sonenshein, G. E. (1999) Cell Growth Differ. 10, 537-544
25. Segev, D. L., Ha, T. U., Tran, T. T., Kenneally, M., Harkin, P., Jung, M., MacLaughlin, D. T., Donahoe, P. K., and Maheswaran, S. (2000) J. Biol. Chem. 275, 28371-28379
26. Liu, Q. Y., Niranjan, B., Gomes, P., Gomm, J. J., Davies, D., Coombes, R. C., and Buluwela, L. (1996) Cancer Res. 56, 1155-1163
27. Ying, S. Y., and Zhang, Z. (1996) Breast Cancer Res. Treat. 37, 151-160
28. de Winter, J. P., Roelen, B. A., ten Dijke, P., van der Burg, B., and van den Eijnden-van Raaij, A. J. (1997) Oncogene 14, 1891-1899
29. Di Loreto, C., Reis, F. M., Cataldi, P., Zuiani, C., Luisi, S., Beltrami, C. A., and Petraglia, F. (1999) Eur. J. Endocrinol. 141, 190-194
30. Chen, T., Carter, D., Garrigue-Antar, L., and Reiss, M. (1998) Cancer Res. 58, 4805-4810
31. Pouliot, F., and Labrie, C. (1999) Int. J. Cancer 81, 98-103
32. Hannon, G. J., and Beach, D. (1994) Nature 371, 257-261
33. Datto, M. B., Li, Y., Panus, J. F., Howe, D. J., Xiong, Y., and Wang, X. F. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 5545-5549
34. Zauberman, A., Oren, M., and Zipori, D. (1997) Oncogene 15, 1705-1711
35. Wu, R. Y., Zhang, Y., Feng, X. H., and Derynek, R. (1997) Mol. Cell. Biol. 17, 2521-2528
36. Eyers, P. A., Craxton, M., Morrice, N., Cohen, P., and Goedert, M. (1998) Chem. Biol. 5, 321-328
37. Massague, J., Blain, S. W., and Lo, R. S. (2000) Cell 103, 295-309
38. Rouse, J., Cohen, P., Trigon, S., Morange, M., Alonso-Llamazares, A., Zamanillo, D., Hunt, T., and Nebreda, A. R. (1994) Cell 78, 1027-1037
39. Freshney, N. W., Rawlinson, L., Guesdon, F., Jones, E., Cowley, S., Hsuan, J., and Saklatvala, J. (1994) Cell 78, 1039-1049
40. Lee, J. C., Laydon, J. T., McDonnell, P. C., Gallagher, T. F., Kumar, S., Green, D., McNulty, D., Blumenthal, M. J., Heys, J. R., Landvatter, S. W., et al. (1994) Nature 372, 739-746
41. Han, J., Lee, J. D., Bibbs, L., and Ulevitch, R. J. (1994) Science 265, 808-811
42. Raingeaud, J., Whitmarsh, A. J., Barrett, T., Derijard, B., and Davis, R. J. (1996) Mol. Cell. Biol. 16, 1247-1255
43. Derijard, B., Raingeaud, J., Barrett, T., Wu, I. H., Han, J., Ulevitch, R. J., and Davis, R. J. (1995) Science 267, 682-685
44. Raingeaud, J., Gupta, S., Rogers, J. S., Dickens, M., Han, J., Ulevitch, R. J., and Davis, R. J. (1995) J. Biol. Chem. 270, 7420-7426
45. Zervos, A. S., Faccio, L., Gatto, J. P., Kyriakis, J. M., and Brent, R. (1995) Proc. Natl. Acad. Sci. U. S.A. 92, 10531-10534
46. Price, M. A., Cruzalegui, F. H., and Treisman, R. (1996) EMBO J. 15, 6552-6563
47. Alam, J., Wicks, C., Stewart, D., Gong, P., Touchard, C., Otterbein, S., Choi, A. M., Burow, M. E., and Tou, J. (2000) J. Biol. Chem. 275, 27694-27702
48. Goh, K. C., Haque, S. J., and Williams, B. R. (1999) EMBO J. 18, 5601-5608
49. Yang, S. H., Galanis, A., and Sharrocks, A. D. (1999) Mol. Cell. Biol. 19, 4028-4038
50. ten Dijke, P., Miyazono, K., and Heldin, C. H. (2000) Trends Biochem. Sci. 25, 64-70
51. Herlaar, E., and Brown, Z. (1999) Mol. Med. Today 5, 439-447
52. Ichijo, H. (1999) Oncogene 18, 6087-6093
53. Yamaguchi, K., Nagai, S., Ninomiya-Tsuji, J., Nishita, M., Tamai, K., Irie, K., Ueno, N., Nishida, E., Shibuya, H., and Matsumoto, K. (1999) EMBO J. 18, 179-187
54. Moriguchi, T., Toyoshima, F., Gotoh, Y., Iwamatsu, A., Irie, K., Mori, E., Kuroyanagi, N., Hagiwara, M., Matsumoto, K., and Nishida, E. (1996) J. Biol. Chem. 271, 26981-26988
55. Ninomiya-Tsuji, J., Kishimoto, K., Hiyama, A., Inoue, J., Cao, Z., and Matsumoto, K. (1999) Nature 398, 252-256