-
1
-
-
30944469849
-
Estrogen carcinogenesis in breast cancer
-
Yager JD, Davidson NE. Estrogen carcinogenesis in breast cancer. N Engl J Med 2006;354:270-282
-
(2006)
N Engl J Med
, vol.354
, pp. 270-282
-
-
Yager, J.D.1
Davidson, N.E.2
-
2
-
-
25844509783
-
Steroid hormone receptor signaling in tumorigenesis
-
DOI 10.1002/jcb.20566
-
Singh RR, Kumar R. Steroid hormone receptor signaling in tumorigenesis. J Cell Biochem 2005;96:490-505. (Pubitemid 41504648)
-
(2005)
Journal of Cellular Biochemistry
, vol.96
, Issue.3
, pp. 490-505
-
-
Singh, R.R.1
Kumar, R.2
-
4
-
-
0037373474
-
The aryl hydrocarbon receptor mediates degradation of estrogen receptor α through activation of proteasomes
-
DOI 10.1128/MCB.23.6.1843-1855.2003
-
Wormke M, Stoner M, Saville B, et al. The aryl hydrocarbon receptor mediates degradation of estrogen receptor α through activation of proteasomes. Mol Cell Biol 2003;23:1843-1855 (Pubitemid 36278799)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.6
, pp. 1843-1855
-
-
Wormke, M.1
Stoner, M.2
Saville, B.3
Walker, K.4
Abdelrahim, M.5
Burghardt, R.6
Safe, S.7
-
5
-
-
34047094888
-
Dioxin receptor is a ligand-dependent E3 ubiquitin ligase
-
DOI 10.1038/nature05683, PII NATURE05683
-
Ohtake F, Baba A, Takada I, et al. Dioxin receptor is a ligand-dependent E3 ubiquitin ligase. Nature 2007;446:562-566 (Pubitemid 46514731)
-
(2007)
Nature
, vol.446
, Issue.7135
, pp. 562-566
-
-
Ohtake, F.1
Baba, A.2
Takada, I.3
Okada, M.4
Iwasaki, K.5
Miki, H.6
Takahashi, S.7
Kouzmenko, A.8
Nohara, K.9
Chiba, T.10
Fujii-Kuriyama, Y.11
Kato, S.12
-
6
-
-
34047136753
-
Cruciferous vegetables and human cancer risk: Epidemiologic evidence and mechanistic basis
-
DOI 10.1016/j.phrs.2007.01.009, PII S1043661807000321, Nutritional Pharmacology
-
Higdon JV, Delage B, Williams DE, Dashwood RH. Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis. Pharmacol Res 2007;55:224-236 (Pubitemid 46518152)
-
(2007)
Pharmacological Research
, vol.55
, Issue.3
, pp. 224-236
-
-
Higdon, J.V.1
Delage, B.2
Williams, D.E.3
Dashwood, R.H.4
-
7
-
-
0028030112
-
Long-term responses of women to indole-3-carbinol or a high fiber diet
-
Bradlow HL, Michnovicz JJ, Halper M, Miller DG, Wong GY, Osborne MP. Long-term responses of women to indole-3-carbinol or a high fiber diet. Cancer Epidemiol Biomarkers Prev 1994;3:591-595 (Pubitemid 24314448)
-
(1994)
Cancer Epidemiology Biomarkers and Prevention
, vol.3
, Issue.7
, pp. 591-595
-
-
Bradlow, H.L.1
Michnovicz, J.J.2
Halper, M.3
Miller, D.G.4
Wong, G.Y.C.5
Osborne, M.P.6
-
8
-
-
0030954304
-
Changes in levels of urinary estrogen metabolites after oral indole-3- Carbinol treatment in humans
-
Michnovicz JJ, Adlercreutz H, Bradlow HL. Changes in levels of urinary estrogen metabolites after oral indole-3-carbinol treatment in humans. J Natl Cancer Inst 1997;89:718-723 (Pubitemid 27229860)
-
(1997)
Journal of the National Cancer Institute
, vol.89
, Issue.10
, pp. 718-723
-
-
Michnovicz, J.J.1
Adlercreutz, H.2
Bradlow, H.L.3
-
9
-
-
0018137952
-
Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles
-
Wattenberg LW, Loub WD. Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles. Cancer Res 1978;38:1410-1413 (Pubitemid 8323347)
-
(1978)
Cancer Research
, vol.38
, Issue.5
, pp. 1410-1413
-
-
Wattenberg, L.W.1
Loub, W.D.2
-
10
-
-
0031715037
-
Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane
-
DOI 10.1093/carcin/19.9.1631
-
Chen I, McDougal A, Wang F, Safe S. Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane. Carcinogenesis 1998;19:1631-1639 (Pubitemid 28441867)
-
(1998)
Carcinogenesis
, vol.19
, Issue.9
, pp. 1631-1639
-
-
Chen, I.1
McDougal, A.2
Wang, F.3
Safe, S.4
-
11
-
-
0027457434
-
Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation
-
Jellinck PH, Forkert PG, Riddick DS, Okey AB, Michnovicz JJ, Bradlow HL. Ah receptor binding properties of indole carbinols and induction of hepatic estradiol hydroxylation. Biochem Pharmacol 1993;45:1129-1136
-
(1993)
Biochem Pharmacol
, vol.45
, pp. 1129-1136
-
-
Jellinck, P.H.1
Forkert, P.G.2
Riddick, D.S.3
Okey, A.B.4
Michnovicz, J.J.5
Bradlow, H.L.6
-
12
-
-
0026046412
-
Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: Comparisons with 2,3,7,8- tetrachlorodibenzo-p-dioxin
-
Bjeldanes LF, Kim JY, Grose KR, Bartholomew JC, Bradfield CA. Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Proc Natl Acad Sci U S A 1991;88:9543-9547
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 9543-9547
-
-
Bjeldanes, L.F.1
Kim, J.Y.2
Grose, K.R.3
Bartholomew, J.C.4
Bradfield, C.A.5
-
13
-
-
0038768712
-
Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
-
Denison MS, Nagy SR. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu Rev Pharmacol Toxicol 2003;43:309-334
-
(2003)
Annu Rev Pharmacol Toxicol
, vol.43
, pp. 309-334
-
-
Denison, M.S.1
Nagy, S.R.2
-
14
-
-
0020010617
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: Examination of the mechanism of toxicity
-
Poland A, Knutson JC. 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu Rev Pharmacol Toxicol 1982;22:517-554
-
(1982)
Annu Rev Pharmacol Toxicol
, vol.22
, pp. 517-554
-
-
Poland, A.1
Knutson, J.C.2
-
15
-
-
34447530842
-
An aryl hydrocarbon receptor odyssey to the shores of toxicology: The Deichmann Lecture, International Congress of Toxicology-XI
-
Okey AB. An aryl hydrocarbon receptor odyssey to the shores of toxicology: the Deichmann Lecture, International Congress of Toxicology-XI. Toxicol Sci 2007;98:5-38.
-
(2007)
Toxicol Sci
, vol.98
, pp. 5-38
-
-
Okey, A.B.1
-
16
-
-
36348987981
-
A dioxin-responsive enhancer 3′ of the human CYP1A2 gene
-
DOI 10.1124/mol.107.039826
-
Okino ST, Quattrochi LC, Pookot D, Iwahashi M, Dahiya R. A dioxin-responsive enhancer 3′ of the human CYP1A2 gene. Mol Pharmacol 2007;72:1457-1465 (Pubitemid 350146083)
-
(2007)
Molecular Pharmacology
, vol.72
, Issue.6
, pp. 1457-1465
-
-
Okino, S.T.1
Quattrochi, L.C.2
Pookot, D.3
Iwahashi, M.4
Dahiya, R.5
-
17
-
-
35148892119
-
Chromatin changes on the GSTP1 promoter associated with its inactivation in prostate cancer
-
DOI 10.1002/mc.20313
-
Okino ST, Pookot D, Majid S, et al. Chromatin changes on the GSTP1 promoter associated with its inactivation in prostate cancer. Mol Carcinog 2007;46:839-846 (Pubitemid 47549769)
-
(2007)
Molecular Carcinogenesis
, vol.46
, Issue.10
, pp. 839-846
-
-
Okino, S.T.1
Pookot, D.2
Majid, S.3
Zhao, H.4
Li, L.-C.5
Place, R.F.6
Dahiya, R.7
-
18
-
-
0038418500
-
Plant-derived 3,3′-diindolylmethane is a strong androgen antagonist in human prostate cancer cells
-
DOI 10.1074/jbc.M300588200
-
Le HT, Schaldach CM, Firestone GL, Bjeldanes LF. Plant-derived 3,3′-diindolylmethane is a strong androgen antagonist in human prostate cancer cells. J Biol Chem 2003;278:21136-21145 (Pubitemid 36806427)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.23
, pp. 21136-21145
-
-
Le, H.T.1
Schaldach, C.M.2
Firestone, G.L.3
Bjeldanes, L.F.4
-
19
-
-
2442672870
-
Physiological modeling of formulated and crystalline 3,3′ -diindolylmethane pharmacokinetics following oral administration in mice
-
DOI 10.1124/dmd.32.6.632
-
Anderton MJ, Manson MM, Verschoyle R, et al. Physiological modeling of formulated and crystalline 3,3′-diindolylmethane pharmacokinetics following oral administration in mice. Drug Metab Dispos 2004;32:632-638 (Pubitemid 38668156)
-
(2004)
Drug Metabolism and Disposition
, vol.32
, Issue.6
, pp. 632-638
-
-
Anderton, M.J.1
Manson, M.M.2
Verschoyle, R.3
Gescher, A.4
Steward, W.P.5
Williams, M.L.6
Mager, D.E.7
-
20
-
-
0000317180
-
Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesis?
-
Zhu BT, Conney AH. Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesis? Cancer Res 1998;58:2269-2277
-
(1998)
Cancer Res
, vol.58
, pp. 2269-2277
-
-
Zhu, B.T.1
Conney, A.H.2
-
21
-
-
35948958167
-
2-Methoxyestradiol suppresses osteolytic breast cancer tumor progression in vivo
-
Cicek M, Iwaniec UT, Goblirsch MJ, et al. 2-Methoxyestradiol suppresses osteolytic breast cancer tumor progression in vivo. Cancer Res 2007;67:10106-10111
-
(2007)
Cancer Res
, vol.67
, pp. 10106-10111
-
-
Cicek, M.1
Iwaniec, U.T.2
Goblirsch, M.J.3
-
22
-
-
0028987872
-
The aryl hydrocarbon receptor complex
-
Hankinson O. The aryl hydrocarbon receptor complex. Annu Rev Pharmacol Toxicol 1995;35:307-340
-
(1995)
Annu Rev Pharmacol Toxicol
, vol.35
, pp. 307-340
-
-
Hankinson, O.1
-
24
-
-
0142027829
-
Agonist and Chemopreventative Ligands Induce Differential Transcriptional Cofactor Recruitment by Aryl Hydrocarbon Receptor
-
DOI 10.1128/MCB.23.21.7920-7925.2003
-
Hestermann EV, Brown M. Agonist and chemopreventative ligands induce differential transcriptional cofactor recruitment by aryl hydrocarbon receptor. Mol Cell Biol 2003;23:7920-7925 (Pubitemid 37271487)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.21
, pp. 7920-7925
-
-
Hestermann, E.V.1
Brown, M.2
-
25
-
-
38949097735
-
The search for endogenous activators of the aryl hydrocarbon receptor
-
Nguyen LP, Bradfield CA. The search for endogenous activators of the aryl hydrocarbon receptor. Chem Res Toxicol 2008;21:102-116
-
(2008)
Chem Res Toxicol
, vol.21
, pp. 102-116
-
-
Nguyen, L.P.1
Bradfield, C.A.2
-
26
-
-
2642510760
-
Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer
-
Nebert DW, Dalton TP, Okey AB, Gonzalez FJ. Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer. J Biol Chem 2004;279:23847-23850
-
(2004)
J Biol Chem
, vol.279
, pp. 23847-23850
-
-
Nebert, D.W.1
Dalton, T.P.2
Okey, A.B.3
Gonzalez, F.J.4
-
27
-
-
0031715037
-
Aryl hydrocarbon receptor-mediated antiestrogenic and antitumorigenic activity of diindolylmethane
-
DOI 10.1093/carcin/19.9.1631
-
Chen I, McDougal A, Wang F, Safe S. Aryl hydrocarbon receptor-mediated anti-estrogenic and antitumorigenic activity of diindolylmethane. Carcinogenesis 1998;19:1631-1639 (Pubitemid 28441867)
-
(1998)
Carcinogenesis
, vol.19
, Issue.9
, pp. 1631-1639
-
-
Chen, I.1
McDougal, A.2
Wang, F.3
Safe, S.4
-
28
-
-
0034646769
-
Inhibition of carcinogen-induced rat mammary tumor growth and other estrogen-dependent responses by symmetrical dihalo-substituted analogs of diindolylmethane
-
DOI 10.1016/S0304-3835(99)00406-1, PII S0304383599004061
-
McDougal A, Gupta MS, Ramamoorthy K, Sun G, Safe SH. Inhibition of carcinogen-induced rat mammary tumor growth and other estrogen-dependent responses by symmetrical dihalo-substituted analogs of diindolylmethane. Cancer Lett 2000;151:169-179 (Pubitemid 30156791)
-
(2000)
Cancer Letters
, vol.151
, Issue.2
, pp. 169-179
-
-
McDougal, A.1
Sethi Gupta, M.2
Ramamoorthy, K.3
Sun, G.4
Safe, S.H.5
-
29
-
-
0030731436
-
Inhibition of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumor growth by aryl hydrocarbon receptor agonists
-
DOI 10.1016/S0304-3835(97)00299-1, PII S0304383597002991
-
McDougal A, Wilson C, Safe S. Inhibition of 7,12-dimethylbenz[a] anthracene-induced rat mammary tumor growth by aryl hydrocarbon receptor agonists. Cancer Lett 1997;120:53-63. (Pubitemid 27483311)
-
(1997)
Cancer Letters
, vol.120
, Issue.1
, pp. 53-63
-
-
McDougal, A.1
Wilson, C.2
Safe, S.3
-
31
-
-
0032842573
-
Development of selective aryl hydrocarbon receptor modulators for treatment of breast cancer
-
DOI 10.1517/13543784.8.9.1385
-
Safe S, Qin C, McDougal A. Development of selective aryl hydrocarbon receptor modulators (SARMs) for treatment of breast cancer. Expert Opin Investig Drugs 1999;8:1385-1396 (Pubitemid 29417622)
-
(1999)
Expert Opinion on Investigational Drugs
, vol.8
, Issue.9
, pp. 1385-1396
-
-
Safe, S.1
Qin, C.2
McDougal, A.3
-
32
-
-
0018074887
-
Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats
-
Kociba RJ, Keyes DG, Beyer JE, et al. Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats. Toxicol Appl Pharmacol 1978;46:279-303.
-
(1978)
Toxicol Appl Pharmacol
, vol.46
, pp. 279-303
-
-
Kociba, R.J.1
Keyes, D.G.2
Beyer, J.E.3
-
33
-
-
0028285283
-
Inhibition of 7,12-dimethyl-benzanthracene-induced rat mammary tumor growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin
-
Holcomb M, Safe S. Inhibition of 7,12-dimethyl-benzanthracene-induced rat mammary tumor growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Cancer Lett 1994;82:43-47
-
(1994)
Cancer Lett
, vol.82
, pp. 43-47
-
-
Holcomb, M.1
Safe, S.2
-
34
-
-
33750541268
-
Down-regulation of androgen receptor by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells
-
DOI 10.1158/0008-5472.CAN-06-2011
-
Bhuiyan MM, Li Y, Banerjee S, et al. Down-regulation of androgen receptor by 3,3′-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells. Cancer Res 2006;66:10064-10072 (Pubitemid 44672060)
-
(2006)
Cancer Research
, vol.66
, Issue.20
, pp. 10064-10072
-
-
Bhuiyan, M.M.R.1
Li, Y.2
Banerjee, S.3
Ahmed, F.4
Wang, Z.5
Ali, S.6
Sarkar, F.H.7
-
36
-
-
0346121452
-
Flavonoids as aryl hydrocarbon receptor agonists/antagonists: Effects of structure and cell context
-
Zhang S, Qin C, Safe SH. Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context. Environ Health Perspect 2003;111:1877-1882 (Pubitemid 37541197)
-
(2003)
Environmental Health Perspectives
, vol.111
, Issue.16
, pp. 1877-1882
-
-
Zhang, S.1
Qin, C.2
Safe, S.H.3
-
37
-
-
0034872657
-
Molecular identification of potential selective estrogen receptor modulator (SERM) like properties of phytoestrogens in the human breast cancer cell line MCF-7
-
DOI 10.1055/s-2001-16474
-
Diel P, Olff S, Schmidt S, Michna H. Molecular identification of potential selective estrogen receptor modulator (SERM) like properties of phytoestrogens in the human breast cancer cell line MCF-7. Planta Med 2001;67:510-514 (Pubitemid 32800414)
-
(2001)
Planta Medica
, vol.67
, Issue.6
, pp. 510-514
-
-
Diel, P.1
Olff, S.2
Schmidt, S.3
Michna, H.4
-
38
-
-
47549100615
-
Genistein differentially modulates androgen-responsive gene expression and activates JNK in LNCaP cells
-
Lazarevic B, Karlsen SJ, Saatcioglu F. Genistein differentially modulates androgen-responsive gene expression and activates JNK in LNCaP cells. Oncol Rep 2008;19:1231-1235
-
(2008)
Oncol Rep
, vol.19
, pp. 1231-1235
-
-
Lazarevic, B.1
Karlsen, S.J.2
Saatcioglu, F.3
-
39
-
-
0036195968
-
Genistein chemoprevention: Timing and mechanisms of action in murine mammary and prostate
-
Lamartiniere CA, Cotroneo MS, Fritz WA, Wang J, Mentor-Marcel R, Elgavish A. Genistein chemoprevention: timing and mechanisms of action in murine mammary and prostate. J Nutr 2002;132:552S-8S. (Pubitemid 34208769)
-
(2002)
Journal of Nutrition
, vol.132
, Issue.3
-
-
Lamartiniere, C.A.1
Cotroneo, M.S.2
Fritz, W.A.3
Wang, J.4
Mentor-Marcel, R.5
Elgavish, A.6
-
40
-
-
52949095784
-
Isoflavones and the prevention of breast and prostate cancer: New perspectives opened by nutrigenomics
-
Steiner C, Amould S, Scalbert A, Manach C. Isoflavones and the prevention of breast and prostate cancer: new perspectives opened by nutrigenomics. Br J Nutr 2008;99 E Suppl 1:ES78-108.
-
(2008)
Br J Nutr
, vol.99 E
, Issue.SUPPL. 1
-
-
Steiner, C.1
Amould, S.2
Scalbert, A.3
Manach, C.4
-
41
-
-
0032842573
-
Development of selective aryl hydrocarbon receptor modulators for treatment of breast cancer
-
DOI 10.1517/13543784.8.9.1385
-
Safe S, Qin C, McDougal A. Development of selective aryl hydrocarbon receptor modulators for treatment of breast cancer. Expert Opin Investig Drugs 1999;8:1385-1396 (Pubitemid 29417622)
-
(1999)
Expert Opinion on Investigational Drugs
, vol.8
, Issue.9
, pp. 1385-1396
-
-
Safe, S.1
Qin, C.2
McDougal, A.3
|