Antitumor benzothiazoles. 14. Synthesis and in vitro biological properties of fluorinated 2-(4-aminophenyl)benzothiazoles

Journal of Medicinal Chemistry

Volumn 44, Issue 9, 2001, Pages 1446-1455

  Hutchinson, I ^a   Chua, M S ^a   Browne, H L ^a   Trapani, V ^a   Bradshaw, T D ^a   Westwell, A D ^a   Stevens, M F G ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 (4 AMINO 3 METHYLPHENYL) 4 FLUOROBENZOTHIAZOLE; 2 (4 AMINO 3 METHYLPHENYL) 5 FLUOROBENZOTHIAZOLE; 2 (4 AMINO 3 METHYLPHENYL) 6 FLUOROBENZOTHIAZOLE; 2 (4 AMINO 3 METHYLPHENYL) 7 FLUOROBENZOTHIAZOLE; 2 (4 AMINOPHENYL)BENZOTHIAZOLE DERIVATIVE; 5,6 DIFLUORO 2 (4 AMINO 3 METHYLPHENYL)BENZOTHIAZOLE; ANTINEOPLASTIC AGENT; BENZOTHIAZOLE DERIVATIVE; CYTOCHROME P450 1A1; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CELL STRAIN MCF 7; CONTROLLED STUDY; CYCLIZATION; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG HYDROXYLATION; DRUG MECHANISM; DRUG METABOLISM; DRUG SYNTHESIS; ENZYME INDUCTION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; PROSTATE CANCER;

ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CYTOCHROME P-450 CYP1A1; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INDUCTION; HUMANS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; TUMOR CELLS, CULTURED;

EID: 0035953321     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm001104n     Document Type: Article

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