Tumor necrosis factor-α increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: A potential mechanism for inflammation-induced carcinogenesis

Cancer Research

Volumn 66, Issue 23, 2006, Pages 11125-11130

  Babbar, Naveen ^a   Casero Jr , Robert A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; HYDROGEN PEROXIDE; INTERLEUKIN 6; N,N' BIS(2,3 BUTADIENYL)PUTRESCINE; OXIDOREDUCTASE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; SPERMIDINE; SPERMINE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CARCINOGENESIS; CHEMOPROPHYLAXIS; DISEASE ASSOCIATION; DISEASE COURSE; DNA DAMAGE; DRUG ACTIVITY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INDUCTION; EPITHELIUM CELL; HUMAN; HUMAN CELL; INFLAMMATION; LUNG ALVEOLUS EPITHELIUM; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ACETYLTRANSFERASES; AGED; AMINO ACID SEQUENCE; BLOTTING, WESTERN; CELL LINE; CELL LINE, TRANSFORMED; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; FEMALE; HUMANS; HYDROGEN PEROXIDE; INFLAMMATION; LUNG; MOLECULAR SEQUENCE DATA; NEOPLASMS; OXIDATION-REDUCTION; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SPERMINE; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33845730779     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-3174     Document Type: Article

References (25)

1. Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420:860-7.
2. 2, and PAF. J Clin Invest 1998;101:890-8.
3. Hodge-Dufour J, Marino MW, Horton MR, et al. Inhibition of Interferon γ induced interleukin 12 production: a potential mechanism for the anti-inflammatory activities of tumor necrosis factor. Proc Natl Acad Sci U S A 1998;95:13806-11.
4. Beutler BA. The role of tumor necrosis factor in health and disease. J Rheumatol Suppl 1999;57:16-21.
5. Balkwill F. Tumor necrosis factor or tumor promoting factor? Cytokine Growth Factor Rev 2002;13:135-41.
6. Szlosarek PW, Grimshaw MJ, Kulbe H, et al. Expression and regulation of tumor necrosis factor α in normal and malignant ovarian epithelium. Mol Cancer Ther 2006;5:382-90.
7. Jaiswal M, LaRusso NF, Burgart LJ, Gores GJ. Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism. Cancer Res 2000;60:184-90.
8. Schulze-Osthoff K, Beyaert R, Vandevoorde V, Haegeman G, Fiers W. Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF. EMBO J 1993;12:3095-104.
9. Chandel NS, Schumacker PT, Arch RH. Reactive oxygen species are downstream products of TRAF-mediated signal transduction. J Biol Chem 2001;276:42728-36.
10. Xu H, Chaturvedi R, Cheng Y, et al. Spermine oxidation induced by Helicobacter pylori results in apoptosis and DNA damage: implications for gastric carcinogenesis. Cancer Res 2004;64:8521-5.
11. Wang Y, Devereux W, Woster PM, Stewart TM, Hacker A, Casero RA, Jr. Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure. Cancer Res 2001;61:5370-3.
12. Ramirez RD, Sheridan S, Girard L, et al. Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins. Cancer Res 2004;64:9027-34.
13. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-9.
14. 1-acetyltransferase (SSAT) through nuclear factor κB in non small cell lung cancer cells. J Biol Chem 2006;281:24182-92.
15. 2 in polyamine analogue-treated human breast cancer cell lines. J Biol Chem 2005;280:39843-51.
16. Tsurudome Y, Hirano T, Yamato H, et al. Changes in levels of 8-hydroxyguanine in DNA, its repair and OGG1 mRNA in rat lungs after intratracheal administration of diesel exhaust particles. Carcinogenesis 1999;20:1573-6.
17. 1-acetyltransferase in human lung cancer cells by the bis(ethyl)polyamine analogues. Cancer Res 1989;49:3829-33.
18. Jackson AL, Loeb LA. The contribution of endogenous sources of DNA damage to the multiple mutations in cancer. Mutat Res 2001;477:7-21.
19. Helbock HJ, Beckman KB, Ames BN. 8-Hydroxydeoxyguanosine and 8-hydroxyguanine as biomarkers of oxidative DNA damage. Methods Enzymol 1999;300:156-66.
20. Janes KA, Gaudet S, Albeck JG, Nielsen UB, Lauffenburger DA, Sorger PK. The response of human epithelial cells to TNF involves an inducible autocrine cascade. Cell 2006;124:1225-39.
21. Wang Y, Casero RA, Jr. Mammalian polyamine catabolism: a therapeutic target, a pathological problem, or both? J Biochem (Tokyo) 2006;139:17-25.
22. Wang Y, Murray-Stewart T, Devereux W, et al. Properties of purified recombinant human polyamine oxidase, PAOhl/SMO. Biochem Biophys Res Commun 2003;304:605-11.
23. Tantini B, Pignatti C, Fattori M, et al. NF-κB and ERK cooperate to stimulate DNA synthesis by inducing omithine decarboxylase and nitric oxide synthase in cardiomyocytes treated with TNF and LPS. FEBS Lett 2002;512:75-9.
24. Scheller J, Rose-John S. Interleukin-6 and its receptor: from bench to bedside. Med Microbiol Immunol (Berl) 2006;195:173-83.
25. Scheller J, Ohnesorge N, Rose-John S. Interleukin-6 trans-signalling in chronic inflammation and cancer. Scand J Immunol 2006;63:321-9.