Preclinical evaluation of amino acid prodrugs of novel antitumor 2-(4-amino-3-methylphenyl)benzothiazoles

Molecular Cancer Therapeutics

Volumn 1, Issue 4, 2002, Pages 239-246

  Bradshaw, Tracey D ^a   Bibby, Michael C ^c   Double, John A ^c   Fichtner, Iduna ^b   Cooper, Patricia A ^c   Alley, Michael C ^d   Donohue, Susan ^d   Stinson, Sherman F ^d   Tomaszewjski, Joseph E ^d   Sausville, Edward A ^d   Stevens, Malcolm F G ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c UNIVERSITY OF BRADFORD   (United Kingdom)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (4 AMINO 3 METHYLPHENYL)BENZOTHIAZOLE; AMINO ACID; ANILINE DERIVATIVE; ANTINEOPLASTIC AGENT; BENZOTHIAZOLE DERIVATIVE; CYTOCHROME P450 1A1; PRODRUG; THIAZOLE DERIVATIVE;

ANIMAL; ARTICLE; CELL CULTURE; CELL DIVISION; DOG; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; ENZYMOLOGY; EXPERIMENTAL NEOPLASM; FEMALE; HUMAN; MALE; METABOLISM; MOUSE; NUDE MOUSE; OVARY TUMOR; RAT; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

AMINO ACIDS; ANILINE COMPOUNDS; ANIMALS; ANTINEOPLASTIC AGENTS; BENZOTHIAZOLES; BLOTTING, WESTERN; CELL DIVISION; CYTOCHROME P-450 CYP1A1; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FEMALE; HUMANS; MALE; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, NUDE; OVARIAN NEOPLASMS; PRODRUGS; RATS; RATS, SPRAGUE-DAWLEY; THIAZOLES; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0036463840     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

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