메뉴 건너뛰기




Volumn 7, Issue 6, 2002, Pages 483-491

Heregulin-induced apoptosis

Author keywords

Apoptosis; Bcl 2; Breast cancer; Caspase 7; HER2; Heregulin

Indexed keywords

CASPASE 7; CASPASE 9; HEREGULIN 2; ISOPROTEIN; JANUS KINASE; MAMMALIAN TARGET OF RAPAMYCIN; NEU DIFFERENTIATION FACTOR; PROTEIN; PROTEIN BCL 2; PROTEIN KINASE C ALPHA; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; CASP7 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE; MITOGEN ACTIVATED PROTEIN KINASE; PRKCA PROTEIN, HUMAN; PROTEIN KINASE; PROTEIN KINASE C;

EID: 0036889246     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020682807922     Document Type: Short Survey
Times cited : (23)

References (67)
  • 1
    • 0030795612 scopus 로고    scopus 로고
    • The ErbB signaling network in embryogenesis and oncogenesis: Signal diversification through combinatorial ligand-receptor interactions
    • Alroy I, Yarden Y. The ErbB signaling network in embryogenesis and oncogenesis: Signal diversification through combinatorial ligand-receptor interactions. FEBS Lett 1997; 410: 83-86.
    • (1997) FEBS Lett , vol.410 , pp. 83-86
    • Alroy, I.1    Yarden, Y.2
  • 2
    • 0031936410 scopus 로고    scopus 로고
    • Specificity within the EGF family/ErbB receptor family signaling network
    • Riese DJ 2nd, Stern DF. Specificity within the EGF family/ErbB receptor family signaling network. Bioessays 1998; 20: 41-48.
    • (1998) Bioessays , vol.20 , pp. 41-48
    • Riese D.J. II1    Stern, D.F.2
  • 3
    • 0034650959 scopus 로고    scopus 로고
    • Role of neuregulin in glial cell development
    • Adlkofer K, Lai C. Role of neuregulin in glial cell development. Glia 2000; 29: 104-111.
    • (2000) Glia , vol.29 , pp. 104-111
    • Adlkofer, K.1    Lai, C.2
  • 4
    • 0026659262 scopus 로고
    • Identification of heregulin: A specific activator of p185erbB2
    • Holmes WE, Sliwkowski MX, Akita RW, et al. Identification of heregulin: A specific activator of p185erbB2. Science 1992; 256: 1205-1210.
    • (1992) Science , vol.256 , pp. 1205-1210
    • Holmes, W.E.1    Sliwkowski, M.X.2    Akita, R.W.3
  • 5
    • 0026776717 scopus 로고
    • Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit
    • Wen D, Peles E, Cuppies R, et al. Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit. Cell 1992; 69: 559-572.
    • (1992) Cell , vol.69 , pp. 559-572
    • Wen, D.1    Peles, E.2    Cuppies, R.3
  • 6
    • 0026776424 scopus 로고
    • Isolation of the neu/HER-2 stimulatory ligand: A 44 kd glycoprotein that induces differentiation of mammary tumor cells
    • Peles E, Bacus SS, Koski RA, et al. Isolation of the neu/HER-2 stimulatory ligand: A 44 kd glycoprotein that induces differentiation of mammary tumor cells. Cell 1992; 69: 205-216.
    • (1992) Cell , vol.69 , pp. 205-216
    • Peles, E.1    Bacus, S.S.2    Koski, R.A.3
  • 7
    • 0027265387 scopus 로고
    • Characterization of a breast cancer cell differentiation factor that specifically activates the HER4/p180erbB4 receptor
    • Culouscou JM, Plowman GD, Carlton GW, et al. Characterization of a breast cancer cell differentiation factor that specifically activates the HER4/p180erbB4 receptor. J Biol Chem 1993; 268: 18407-18410.
    • (1993) J Biol Chem , vol.268 , pp. 18407-18410
    • Culouscou, J.M.1    Plowman, G.D.2    Carlton, G.W.3
  • 8
    • 0030974096 scopus 로고    scopus 로고
    • Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases
    • Carraway KL 3rd, Weber JL, Unger MJ, et al. Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases. Nature 1997; 387: 512-516.
    • (1997) Nature , vol.387 , pp. 512-516
    • Carraway K.L. III1    Weber, J.L.2    Unger, M.J.3
  • 9
    • 0030911331 scopus 로고    scopus 로고
    • Ligands for ErbB-family receptors encoded by a neuregulin-like gene
    • Chang H, Riese DJ 2nd, Gilbert W, et al. Ligands for ErbB-family receptors encoded by a neuregulin-like gene. Nature 1997; 387: 509-512.
    • (1997) Nature , vol.387 , pp. 509-512
    • Chang, H.1    Riese D.J. II2    Gilbert, W.3
  • 10
    • 12644279865 scopus 로고    scopus 로고
    • Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4
    • Zhang D, Sliwkowski MX, Mark M, et al. Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4. Proc Natl Acad Sci USA 1997; 94: 9562-9567.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 9562-9567
    • Zhang, D.1    Sliwkowski, M.X.2    Mark, M.3
  • 11
    • 0033614356 scopus 로고    scopus 로고
    • Neuregulin-4: A novel growth factor that acts through the ErbB-4 receptor tyrosine kinase
    • Harari D, Tzahar E, Romano J, et al. Neuregulin-4: A novel growth factor that acts through the ErbB-4 receptor tyrosine kinase. Oncogene 1999; 18: 2681-2689.
    • (1999) Oncogene , vol.18 , pp. 2681-2689
    • Harari, D.1    Tzahar, E.2    Romano, J.3
  • 12
    • 0027408665 scopus 로고
    • Neural expression and chromosomal mapping of Neu differentiation factor to 8p12-p21
    • Orr-Urtreger A, Trakhtenbrot L, Ben-Levy R, et al. Neural expression and chromosomal mapping of Neu differentiation factor to 8p12-p21. Proc Natl Acad Sci USA 1993; 90: 1867-1871.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1867-1871
    • Orr-Urtreger, A.1    Trakhtenbrot, L.2    Ben-Levy, R.3
  • 13
    • 0032973255 scopus 로고    scopus 로고
    • The human neuregulin-2 gene: Cloning, mapping and evaluation as a candidate for the autosomal recessive form of Charcot-Marie-Tooth disease linked to 5q
    • Ring HZ, Chang H, Guilbot A, et al. The human neuregulin-2 gene: Cloning, mapping and evaluation as a candidate for the autosomal recessive form of Charcot-Marie-Tooth disease linked to 5q. Hum Genet 1999; 104: 326-332.
    • (1999) Hum Genet , vol.104 , pp. 326-332
    • Ring, H.Z.1    Chang, H.2    Guilbot, A.3
  • 15
    • 0031705405 scopus 로고    scopus 로고
    • ErbB tyrosine kinases and the two neuregulin families constitute a ligand-receptor network
    • Pinkas-Kramarski R, Shelly M, Guarino BC, et al. ErbB tyrosine kinases and the two neuregulin families constitute a ligand-receptor network. Mol Cell Biol 1998; 18: 6090-6101.
    • (1998) Mol Cell Biol , vol.18 , pp. 6090-6101
    • Pinkas-Kramarski, R.1    Shelly, M.2    Guarino, B.C.3
  • 16
    • 0033009389 scopus 로고    scopus 로고
    • Binding specificity and affinity of EGF domains for ErbB receptors
    • Jones JT, Akita RW, Sliwkowski MX. Binding specificity and affinity of EGF domains for ErbB receptors. FEBS Lett 1999; 447: 227-231.
    • (1999) FEBS Lett , vol.447 , pp. 227-231
    • Jones, J.T.1    Akita, R.W.2    Sliwkowski, M.X.3
  • 17
    • 0034235598 scopus 로고    scopus 로고
    • HER2 with a monoclonal antibody and with heregulin β1 in SKBr3 cells
    • HER2 with a monoclonal antibody and with heregulin β1 in SKBr3 cells. Cancer Res 2000; 60: 3522-3531.
    • (2000) Cancer Res , vol.60 , pp. 3522-3531
    • Le, X.F.1    Vadlamudi, R.2    McWatters, A.3
  • 18
    • 0036494178 scopus 로고    scopus 로고
    • Heregulin induces expression, ATPase activity, and nuclear localization of G3BP, a Ras signaling component, in human breast tumors
    • Barnes CJ, Li F, Mandal M, Yang Z, et al. Heregulin induces expression, ATPase activity, and nuclear localization of G3BP, a Ras signaling component, in human breast tumors. Cancer Res 2002; 62: 1251-1255.
    • (2002) Cancer Res , vol.62 , pp. 1251-1255
    • Barnes, C.J.1    Li, F.2    Mandal, M.3    Yang, Z.4
  • 19
    • 0028827104 scopus 로고
    • Multiple essential functions of neuregulin in development
    • Meyer D, Birchmeier C. Multiple essential functions of neuregulin in development. Nature 1995; 378: 386-390.
    • (1995) Nature , vol.378 , pp. 386-390
    • Meyer, D.1    Birchmeier, C.2
  • 20
    • 0028785406 scopus 로고
    • Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor
    • Gassmann M, Casagranda F, Orioli D, et al. Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature 1995; 378: 390-394.
    • (1995) Nature , vol.378 , pp. 390-394
    • Gassmann, M.1    Casagranda, F.2    Orioli, D.3
  • 21
    • 0028884413 scopus 로고
    • Requirement for neuregulin receptor erbB2 in neural and cardiac development
    • Lee KF, Simon H, Chen H, et al. Requirement for neuregulin receptor erbB2 in neural and cardiac development. Nature 1995; 378: 394-398.
    • (1995) Nature , vol.378 , pp. 394-398
    • Lee, K.F.1    Simon, H.2    Chen, H.3
  • 22
    • 0029879442 scopus 로고    scopus 로고
    • Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness
    • Lewis GD, Lofgren JA, McMurtrey AE, et al. Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness. Cancer Res 1996; 56: 1457-1465.
    • (1996) Cancer Res , vol.56 , pp. 1457-1465
    • Lewis, G.D.1    Lofgren, J.A.2    McMurtrey, A.E.3
  • 23
    • 0029965411 scopus 로고    scopus 로고
    • Epidermal growth factor-related peptides activate distinct subsets of ErbB receptors and differ in their biological activities
    • Beerli RR, Hynes NE. Epidermal growth factor-related peptides activate distinct subsets of ErbB receptors and differ in their biological activities. J Biol Chem 1996; 271: 6071-6076.
    • (1996) J Biol Chem , vol.271 , pp. 6071-6076
    • Beerli, R.R.1    Hynes, N.E.2
  • 24
    • 0033613354 scopus 로고    scopus 로고
    • Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells
    • Aguilar Z, Akita RW, Finn RS, et al. Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells. Oncogene 1999; 18: 6050-6062.
    • (1999) Oncogene , vol.18 , pp. 6050-6062
    • Aguilar, Z.1    Akita, R.W.2    Finn, R.S.3
  • 25
    • 0034660867 scopus 로고    scopus 로고
    • The extracellular region of heregulin is sufficient to promote mammary gland proliferation and tumorigenesis but not apoptosis
    • Weinstein EJ, Leder P. The extracellular region of heregulin is sufficient to promote mammary gland proliferation and tumorigenesis but not apoptosis. Cancer Res 2000; 60: 3856-3861.
    • (2000) Cancer Res , vol.60 , pp. 3856-3861
    • Weinstein, E.J.1    Leder, P.2
  • 26
    • 0029912447 scopus 로고    scopus 로고
    • NDF/heregulin induces persistence of terminal end buds and adenocarcinomas in the mammary glands of transgenic mice
    • Krane IM, Leder P. NDF/heregulin induces persistence of terminal end buds and adenocarcinomas in the mammary glands of transgenic mice. Oncogene 1996; 12: 1781-1788.
    • (1996) Oncogene , vol.12 , pp. 1781-1788
    • Krane, I.M.1    Leder, P.2
  • 27
    • 0034671927 scopus 로고    scopus 로고
    • Vascular endothelial growth factor upregulation via p21-activated kinase-1 signaling regulates heregulin-beta1-mediated angiogenesis
    • Bagheri-Yarmand R, Vadlamudi RK, Wang RA, et al. Vascular endothelial growth factor upregulation via p21-activated kinase-1 signaling regulates heregulin-beta1-mediated angiogenesis. J Biol Chem 2000; 275: 39451-39457.
    • (2000) J Biol Chem , vol.275 , pp. 39451-39457
    • Bagheri-Yarmand, R.1    Vadlamudi, R.K.2    Wang, R.A.3
  • 28
    • 0034691674 scopus 로고    scopus 로고
    • Heregulin selectively up-regulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis
    • Yen L, You XL, Al Moustafa AE, et al. Heregulin selectively up-regulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis. Oncogene 2000; 19: 3460-3469.
    • (2000) Oncogene , vol.19 , pp. 3460-3469
    • Yen, L.1    You, X.L.2    Al Moustafa, A.E.3
  • 29
    • 0030879101 scopus 로고    scopus 로고
    • Heregulin and agonistic anti-p185(c-erbB2) antibodies inhibit proliferation but increase invasiveness of breast cancer cells that overexpress p185(c-erbB2): Increased invasiveness may contribute to poor prognosis
    • Xu FJ, Stack S, Boyer C, et al. Heregulin and agonistic anti-p185(c-erbB2) antibodies inhibit proliferation but increase invasiveness of breast cancer cells that overexpress p185(c-erbB2): Increased invasiveness may contribute to poor prognosis. Clin Cancer Res 1997; 3: 1629-1634.
    • (1997) Clin Cancer Res , vol.3 , pp. 1629-1634
    • Xu, F.J.1    Stack, S.2    Boyer, C.3
  • 30
    • 0033106477 scopus 로고    scopus 로고
    • Heregulin beta1-activated phosphatidylinositol 3-kinase enhances aggregation of MCF-7 breast cancer cells independent of extracellular signal-regulated kinase
    • Tan M, Grijalva R, Yu D. Heregulin beta1-activated phosphatidylinositol 3-kinase enhances aggregation of MCF-7 breast cancer cells independent of extracellular signal-regulated kinase. Cancer Res 1999; 59: 1620-1625.
    • (1999) Cancer Res , vol.59 , pp. 1620-1625
    • Tan, M.1    Grijalva, R.2    Yu, D.3
  • 31
    • 0034293169 scopus 로고    scopus 로고
    • Heregulin regulates the acrin cytoskeleton and promotes invasive properties in breast cancer cell lines
    • Hijazi MM, Thompson EW, Tang C, et al. Heregulin regulates the acrin cytoskeleton and promotes invasive properties in breast cancer cell lines. Int J Oncol 2000; 17: 629-641.
    • (2000) Int J Oncol , vol.17 , pp. 629-641
    • Hijazi, M.M.1    Thompson, E.W.2    Tang, C.3
  • 32
    • 0026899636 scopus 로고
    • A ligand for the erbB-2 oncogene product (gp30) induces differentiation of human breast cancer cells
    • Bacus SS, Huberman E, Chin D, et al. A ligand for the erbB-2 oncogene product (gp30) induces differentiation of human breast cancer cells. Cell Growth Differ 1992; 3: 401-411.
    • (1992) Cell Growth Differ , vol.3 , pp. 401-411
    • Bacus, S.S.1    Huberman, E.2    Chin, D.3
  • 33
    • 0030768379 scopus 로고    scopus 로고
    • Neu differentiation factor induces ErbB2 down-regulation and apoptosis of ErbB2-overexpressing breast tumor cells
    • Daly JM, Jannot CB, Beerli RR, et al. Neu differentiation factor induces ErbB2 down-regulation and apoptosis of ErbB2-overexpressing breast tumor cells. Cancer Res 1997; 57: 3804-3811.
    • (1997) Cancer Res , vol.57 , pp. 3804-3811
    • Daly, J.M.1    Jannot, C.B.2    Beerli, R.R.3
  • 34
    • 0033965065 scopus 로고    scopus 로고
    • Anti-HER2 antibody and heregulin suppress growth of HER2-overexpressing human breast cancer cells through different mechanisms
    • Le XF, McWatters A, Wiener J, et al. Anti-HER2 antibody and heregulin suppress growth of HER2-overexpressing human breast cancer cells through different mechanisms. Clin Cancer Res 2000; 6: 260-270.
    • (2000) Clin Cancer Res , vol.6 , pp. 260-270
    • Le, X.F.1    McWatters, A.2    Wiener, J.3
  • 35
    • 10244279259 scopus 로고    scopus 로고
    • Heregulin induces in vivo proliferation and differentiation of mammary epithelium into secretory lobuloalveoli
    • Jones FE, Jerry DJ, Guarino BC, et al. Heregulin induces in vivo proliferation and differentiation of mammary epithelium into secretory lobuloalveoli. Cell Growth Differ 1996; 7: 1031-1038.
    • (1996) Cell Growth Differ , vol.7 , pp. 1031-1038
    • Jones, F.E.1    Jerry, D.J.2    Guarino, B.C.3
  • 36
    • 0030959526 scopus 로고    scopus 로고
    • An apoptosis-inducing isoform of neu differentiation factor (NDF) identified using a novel screen for dominant, apoptosis-inducing genes
    • Grimm S, Leder P. An apoptosis-inducing isoform of neu differentiation factor (NDF) identified using a novel screen for dominant, apoptosis-inducing genes. J Exp Med 1997; 185: 1137-1142.
    • (1997) J Exp Med , vol.185 , pp. 1137-1142
    • Grimm, S.1    Leder, P.2
  • 37
    • 0032547766 scopus 로고    scopus 로고
    • Neu differentiation factor (NDF): A dominant oncogene, causes apoptosis in vitro and in vivo
    • Grimm S, Weinstein EJ, Krane IM, Leder P. Neu differentiation factor (NDF): A dominant oncogene, causes apoptosis in vitro and in vivo. J Exp Med 1998; 188: 1535-1539.
    • (1998) J Exp Med , vol.188 , pp. 1535-1539
    • Grimm, S.1    Weinstein, E.J.2    Krane, I.M.3    Leder, P.4
  • 38
    • 0032558736 scopus 로고    scopus 로고
    • The oncogene heregulin induces apoptosis in breast epithelial cells and tumors
    • Weinstein EJ, Grimm S, Leder P. The oncogene heregulin induces apoptosis in breast epithelial cells and tumors. Oncogene 1998; 17: 2107-2113.
    • (1998) Oncogene , vol.17 , pp. 2107-2113
    • Weinstein, E.J.1    Grimm, S.2    Leder, P.3
  • 39
    • 0033542379 scopus 로고    scopus 로고
    • NDF/heregulin-induced cell cycle changes and apoptosis in breast tumour cells: Role of P13 kinase and p38 MAP kinase pathways
    • Daly JM, Olayioye MA, Wong AM, et al. NDF/heregulin-induced cell cycle changes and apoptosis in breast tumour cells: Role of P13 kinase and p38 MAP kinase pathways. Oncogene 1999; 18: 3440-3451.
    • (1999) Oncogene , vol.18 , pp. 3440-3451
    • Daly, J.M.1    Olayioye, M.A.2    Wong, A.M.3
  • 40
    • 0033227253 scopus 로고    scopus 로고
    • Constitutive expression of Heregulin induces apoptosis in an erbB-2 over-expressing breast cancer cell line SKBr-3
    • Guerra-Vladusic FK, Scott G, Weaver V, et al. Constitutive expression of Heregulin induces apoptosis in an erbB-2 over-expressing breast cancer cell line SKBr-3. Int J Oncol 1999; 15: 883-892.
    • (1999) Int J Oncol , vol.15 , pp. 883-892
    • Guerra-Vladusic, F.K.1    Scott, G.2    Weaver, V.3
  • 41
    • 0035857113 scopus 로고    scopus 로고
    • Heregulin-induced apoptosis is mediated by down-regulation of Bcl-2 and activation of caspase-7 and is potentiated by impairment of protein kinase C alpha activity
    • Le XF, Marcelli M, McWarrers A, et al. Heregulin-induced apoptosis is mediated by down-regulation of Bcl-2 and activation of caspase-7 and is potentiated by impairment of protein kinase C alpha activity. Oncogene 2001; 20: 8258-8269.
    • (2001) Oncogene , vol.20 , pp. 8258-8269
    • Le, X.F.1    Marcelli, M.2    McWarrers, A.3
  • 42
    • 0032713438 scopus 로고    scopus 로고
    • The outcome of heregulin-induced activation of ovarian cancer cells depends on the relative levels of HER-2 and HER-3 expression
    • Xu FJ, Yu YH, Le XF, et al. The outcome of heregulin-induced activation of ovarian cancer cells depends on the relative levels of HER-2 and HER-3 expression. Clin Cancer Res 1999; 5: 3653-3660.
    • (1999) Clin Cancer Res , vol.5 , pp. 3653-3660
    • Xu, F.J.1    Yu, Y.H.2    Le, X.F.3
  • 43
    • 0032581532 scopus 로고    scopus 로고
    • Increased expression of c-erbB-2 in hormone-dependent breast cancer cells inhibits cell growth and induces differentiation
    • Giani C, Casalini P, Pupa SM, et al. Increased expression of c-erbB-2 in hormone-dependent breast cancer cells inhibits cell growth and induces differentiation. Oncogene 1998; 17: 425-432.
    • (1998) Oncogene , vol.17 , pp. 425-432
    • Giani, C.1    Casalini, P.2    Pupa, S.M.3
  • 44
    • 0029928763 scopus 로고    scopus 로고
    • Signal transduction pathways induced by heregulin in MDA-MB-453 breast cancer cells
    • Sepp-Lorenzino L, Eberhard I, Ma Z, et al. Signal transduction pathways induced by heregulin in MDA-MB-453 breast cancer cells. Oncogene 1996; 12: 1679-1687.
    • (1996) Oncogene , vol.12 , pp. 1679-1687
    • Sepp-Lorenzino, L.1    Eberhard, I.2    Ma, Z.3
  • 45
    • 0034967966 scopus 로고    scopus 로고
    • HER4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells
    • Sartor CI, Zhou H, Kozlowska E, et al. HER4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells. Mol Cell Biol 2001; 21: 4265-4275.
    • (2001) Mol Cell Biol , vol.21 , pp. 4265-4275
    • Sartor, C.I.1    Zhou, H.2    Kozlowska, E.3
  • 46
    • 0035515236 scopus 로고    scopus 로고
    • Signaling molecules implicated in heregulin induction of growth arrest and apoptosis
    • Guerra-Vladusic FK, Vladusic EA, Tsai MS, Lupu R. Signaling molecules implicated in heregulin induction of growth arrest and apoptosis. Oncol Rep 2001; 8: 1203-1214.
    • (2001) Oncol Rep , vol.8 , pp. 1203-1214
    • Guerra-Vladusic, F.K.1    Vladusic, E.A.2    Tsai, M.S.3    Lupu, R.4
  • 47
    • 0028022750 scopus 로고
    • A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
    • Rouse J, Cohen P, Trigon S, et al. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell 1994; 78: 1027-1037.
    • (1994) Cell , vol.78 , pp. 1027-1037
    • Rouse, J.1    Cohen, P.2    Trigon, S.3
  • 48
    • 0035212589 scopus 로고    scopus 로고
    • The ups and downs of MEK kinase interactions
    • Hagemann C, Blank JL. The ups and downs of MEK kinase interactions. Cell Signal 2001; 13: 863-875.
    • (2001) Cell Signal , vol.13 , pp. 863-875
    • Hagemann, C.1    Blank, J.L.2
  • 49
    • 0032573378 scopus 로고    scopus 로고
    • Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases
    • Caron E, Hall A. Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases. Science 1998; 282: 1717-1721.
    • (1998) Science , vol.282 , pp. 1717-1721
    • Caron, E.1    Hall, A.2
  • 50
    • 0032518818 scopus 로고    scopus 로고
    • CD66-mediated phagocytosis of Opa52 Neisseria gonorrhoeae requires a Src-like tyrosine kinase- and Rac1-dependent signalling pathway
    • Hauck CR, Meyer TF, Lang F, Gulbins E. CD66-mediated phagocytosis of Opa52 Neisseria gonorrhoeae requires a Src-like tyrosine kinase- and Rac1-dependent signalling pathway. EMBOJ 1998; 17: 443-454.
    • (1998) EMBOJ , vol.17 , pp. 443-454
    • Hauck, C.R.1    Meyer, T.F.2    Lang, F.3    Gulbins, E.4
  • 51
    • 0032609465 scopus 로고    scopus 로고
    • Making the connection: Coupling of stress-activated ERK/MAPK (extracellular-signal-regulated kinase/mitogen-activated protein kinase) core signalling modules to extracellular stimuli and biological responses
    • Kyriakis JM. Making the connection: Coupling of stress-activated ERK/MAPK (extracellular-signal-regulated kinase/mitogen-activated protein kinase) core signalling modules to extracellular stimuli and biological responses. Biochem Soc Symp 1999; 64: 29-48.
    • (1999) Biochem Soc Symp , vol.64 , pp. 29-48
    • Kyriakis, J.M.1
  • 53
    • 0035923665 scopus 로고    scopus 로고
    • SP600125: An anthrapyrazolone inhibitor of Jun N-terminal kinase
    • Bennett BL, Sasaki DT, Murray BW, et al. SP600125: An anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci USA 2001; 98: 13681-13686.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13681-13686
    • Bennett, B.L.1    Sasaki, D.T.2    Murray, B.W.3
  • 54
    • 0033574434 scopus 로고    scopus 로고
    • Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents
    • Gibson S, Widmann C, Johnson GL. Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents. J Biol Chem 1999; 274: 10916-10922.
    • (1999) J Biol Chem , vol.274 , pp. 10916-10922
    • Gibson, S.1    Widmann, C.2    Johnson, G.L.3
  • 55
    • 0030458602 scopus 로고    scopus 로고
    • A role for Jun-N-terminal kinase in anoikis; Suppression by Bcl-2 and crmA
    • Frisch SM, Vuori K, Kelaita D, Sicks S. A role for Jun-N-terminal kinase in anoikis; Suppression by Bcl-2 and crmA. J Biol Chem 1996; 135: 1377-1382.
    • (1996) J Biol Chem , vol.135 , pp. 1377-1382
    • Frisch, S.M.1    Vuori, K.2    Kelaita, D.3    Sicks, S.4
  • 59
    • 0033499801 scopus 로고    scopus 로고
    • Bcl-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M
    • Yamamoto K, Ichijo H, Korsmeyer, SJ. Bcl-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M. Mol Cell Biol 1999; 19: 8469-8478.
    • (1999) Mol Cell Biol , vol.19 , pp. 8469-8478
    • Yamamoto, K.1    Ichijo, H.2    Korsmeyer, S.J.3
  • 60
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry NA, Lazebnik Y. Caspases: Enemies within. Science 1998; 281: 1312-1316.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.A.1    Lazebnik, Y.2
  • 61
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A, Dixit VM. Death receptors: Signaling and modulation. Science 1998; 281: 1305-1308.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 62
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR, Reed JC. Mitochondria and apoptosis. Science 1998; 281: 1309-1312.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 63
    • 0034610743 scopus 로고    scopus 로고
    • Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid
    • Nakagawa T, Zhu H, Morishima N, et al. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid. Nature 2000; 403: 98-103.
    • (2000) Nature , vol.403 , pp. 98-103
    • Nakagawa, T.1    Zhu, H.2    Morishima, N.3
  • 67
    • 0034634596 scopus 로고    scopus 로고
    • Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex
    • Bourbon NA, Yun J, Kester M. Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex. J Biol Chem 2000; 275: 35617-35623.
    • (2000) J Biol Chem , vol.275 , pp. 35617-35623
    • Bourbon, N.A.1    Yun, J.2    Kester, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.