메뉴 건너뛰기




Volumn 7, Issue 3, 2015, Pages 377-391

Angiogenesis and liver fibrosis

Author keywords

Angiogenesis; Chronic liver disease; Cirrhosis; Fibrogenesis; Hepatic stellate cells; Hypoxia; Liver fibrosis; Vascular endothelial growth factor

Indexed keywords


EID: 84928953152     PISSN: None     EISSN: 19485182     Source Type: Journal    
DOI: 10.4254/wjh.v7.i3.377     Document Type: Article
Times cited : (133)

References (147)
  • 1
    • 84856739946 scopus 로고    scopus 로고
    • Hypoxia-inducible factors in physiology and medicine
    • PMID: 22304911
    • Semenza GL. Hypoxia-inducible factors in physiology and medicine. Cell 2012; 148: 399-408 [PMID: 22304911 DOI:10.1016/j.cell.2012.01.021]
    • (2012) Cell , vol.148 , pp. 399-408
    • Semenza, G.L.1
  • 2
    • 79956328903 scopus 로고    scopus 로고
    • Molecular mechanisms and clinical applications of angiogenesis
    • PMID:21593862
    • Carmeliet P, Jain RK. Molecular mechanisms and clinical applications of angiogenesis. Nature 2011; 473: 298-307 [PMID:21593862 DOI: 10.1038/nature10144]
    • (2011) Nature , vol.473 , pp. 298-307
    • Carmeliet, P.1    Jain, R.K.2
  • 4
    • 59649112848 scopus 로고    scopus 로고
    • Regulation of angiogenesis by oxygen and metabolism
    • PMID: 19217420
    • Fraisl P, Mazzone M, Schmidt T, Carmeliet P. Regulation of angiogenesis by oxygen and metabolism. Dev Cell 2009; 16:167-179 [PMID: 19217420 DOI: 10.1016/j.devcel.2009.01.003]
    • (2009) Dev Cell , vol.16 , pp. 167-179
    • Fraisl, P.1    Mazzone, M.2    Schmidt, T.3    Carmeliet, P.4
  • 8
    • 71749091179 scopus 로고    scopus 로고
    • Angiogenesis in chronic hepatitis C is associated with inflammatory activity grade and fibrosis stage
    • PMID: 19592175
    • Gabriel A, Kukla M, Wilk M, Liszka Ł, Petelenz M, Musialik J. Angiogenesis in chronic hepatitis C is associated with inflammatory activity grade and fibrosis stage. Pathol Res Pract 2009; 205:758-764 [PMID: 19592175 DOI: 10.1016/j.prp.2009.06.007]
    • (2009) Pathol Res Pract , vol.205 , pp. 758-764
    • Gabriel, A.1    Kukla, M.2    Wilk, M.3    Liszka, Ł4    Petelenz, M.5    Musialik, J.6
  • 10
    • 84875273697 scopus 로고    scopus 로고
    • Hepatic angiogenesis and fibrosis are common features in morbidly obese patients
    • PMID: 23519653
    • Ciupińska-Kajor M, Hartleb M, Kajor M, Kukla M, Wylezoł M, Lange D, Liszka L. Hepatic angiogenesis and fibrosis are common features in morbidly obese patients. Hepatol Int 2013; 7: 233-240 [PMID: 23519653 DOI: 10.1007/s12072-011-9320-9]
    • (2013) Hepatol Int , vol.7 , pp. 233-240
    • Ciupińska-Kajor, M.1    Hartleb, M.2    Kajor, M.3    Kukla, M.4    Wylezoł, M.5    Lange, D.6    Liszka, L.7
  • 11
    • 65449167923 scopus 로고    scopus 로고
    • Antiangiogenic therapy: not just for cancer anymore?
    • PMID: 19330868
    • Shah VH, Bruix J. Antiangiogenic therapy: not just for cancer anymore? Hepatology 2009; 49: 1066-1068 [PMID: 19330868 DOI: 10.1002/hep.22872]
    • (2009) Hepatology , vol.49 , pp. 1066-1068
    • Shah, V.H.1    Bruix, J.2
  • 12
    • 77953506000 scopus 로고    scopus 로고
    • Angiogenesis: from chronic liver inflammation to hepatocellular carcinoma
    • PMID:20592752
    • Sanz-Cameno P, Trapero-Marugán M, Chaparro M, Jones EA, Moreno-Otero R. Angiogenesis: from chronic liver inflammation to hepatocellular carcinoma. J Oncol 2010; 2010: 272170 [PMID:20592752 DOI: 10.1155/2010/272170]
    • (2010) J Oncol , vol.2010 , pp. 272170
    • Sanz-Cameno, P.1    Trapero-Marugán, M.2    Chaparro, M.3    Jones, E.A.4    Moreno-Otero, R.5
  • 14
    • 84906535982 scopus 로고    scopus 로고
    • Roles for chemokines in liver disease
    • PMID: 25066692
    • Marra F, Tacke F. Roles for chemokines in liver disease. Gastroenterology 2014; 147: 577-594.e1 [PMID: 25066692 DOI:10.1053/j.gastro.2014.06.043]
    • (2014) Gastroenterology , vol.147 , pp. 577-594.e1
    • Marra, F.1    Tacke, F.2
  • 16
    • 84904238915 scopus 로고    scopus 로고
    • Neutrophil-derived cytokines involved in physiological and pathological angiogenesis
    • PMID: 24217606
    • Tecchio C, Cassatella MA. Neutrophil-derived cytokines involved in physiological and pathological angiogenesis. Chem Immunol Allergy 2014; 99: 123-137 [PMID: 24217606 DOI: 10.1159/000353358]
    • (2014) Chem Immunol Allergy , vol.99 , pp. 123-137
    • Tecchio, C.1    Cassatella, M.A.2
  • 17
    • 84904226806 scopus 로고    scopus 로고
    • Angiogenic and antiangiogenic chemokines
    • PMID: 24217604
    • Bosisio D, Salvi V, Gagliostro V, Sozzani S. Angiogenic and antiangiogenic chemokines. Chem Immunol Allergy 2014; 99:89-104 [PMID: 24217604 DOI: 10.1159/000353317]
    • (2014) Chem Immunol Allergy , vol.99 , pp. 89-104
    • Bosisio, D.1    Salvi, V.2    Gagliostro, V.3    Sozzani, S.4
  • 18
    • 0037284514 scopus 로고    scopus 로고
    • Chemokines in the pathogenesis of liver disease: so many players with poorly defined roles
    • Lond, PMID: 12519087
    • Simpson KJ, Henderson NC, Bone-Larson CL, Lukacs NW, Hogaboam CM, Kunkel SL. Chemokines in the pathogenesis of liver disease: so many players with poorly defined roles. Clin Sci (Lond) 2003; 104: 47-63 [PMID: 12519087 DOI: 10.1042/ CS20020137]
    • (2003) Clin Sci , vol.104 , pp. 47-63
    • Simpson, K.J.1    Henderson, N.C.2    Bone-Larson, C.L.3    Lukacs, N.W.4    Hogaboam, C.M.5    Kunkel, S.L.6
  • 19
    • 77955010960 scopus 로고    scopus 로고
    • Hypoxia: a link between fibrogenesis, angiogenesis, and carcinogenesis in liver disease
    • PMID: 20665378
    • Rosmorduc O, Housset C. Hypoxia: a link between fibrogenesis, angiogenesis, and carcinogenesis in liver disease. Semin Liver Dis 2010; 30: 258-270 [PMID: 20665378 DOI: 10.1055/s-0030-1255355]
    • (2010) Semin Liver Dis , vol.30 , pp. 258-270
    • Rosmorduc, O.1    Housset, C.2
  • 20
    • 65349175992 scopus 로고    scopus 로고
    • Reduced liver fibrosis in hypoxia-inducible factor-1alpha-deficient mice
    • PMID:19136383
    • Moon JO, Welch TP, Gonzalez FJ, Copple BL. Reduced liver fibrosis in hypoxia-inducible factor-1alpha-deficient mice. Am J Physiol Gastrointest Liver Physiol 2009; 296: G582-G592 [PMID:19136383 DOI: 10.1152/ajpgi.90368.2008]
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296 , pp. G582-G592
    • Moon, J.O.1    Welch, T.P.2    Gonzalez, F.J.3    Copple, B.L.4
  • 22
    • 75349086017 scopus 로고    scopus 로고
    • Hypoxia, angiogenesis and liver fibrogenesis in the progression of chronic liver diseases
    • PMID: 20082471
    • Paternostro C, David E, Novo E, Parola M. Hypoxia, angiogenesis and liver fibrogenesis in the progression of chronic liver diseases. World J Gastroenterol 2010; 16: 281-288 [PMID: 20082471 DOI:10.3748/wjg.v16.i3.281]
    • (2010) World J Gastroenterol , vol.16 , pp. 281-288
    • Paternostro, C.1    David, E.2    Novo, E.3    Parola, M.4
  • 23
    • 84875158140 scopus 로고    scopus 로고
    • HIFs, angiogenesis, and cancer
    • PMID: 23225225
    • Yang Y, Sun M, Wang L, Jiao B. HIFs, angiogenesis, and cancer. J Cell Biochem 2013; 114: 967-974 [PMID: 23225225 DOI: 10.1002/ jcb.24438]
    • (2013) J Cell Biochem , vol.114 , pp. 967-974
    • Yang, Y.1    Sun, M.2    Wang, L.3    Jiao, B.4
  • 24
    • 84856390541 scopus 로고    scopus 로고
    • Hypoxia and hypoxia inducible factors: diverse roles in liver diseases
    • PMID:22120903
    • Nath B, Szabo G. Hypoxia and hypoxia inducible factors: diverse roles in liver diseases. Hepatology 2012; 55: 622-633 [PMID:22120903 DOI: 10.1002/hep.25497]
    • (2012) Hepatology , vol.55 , pp. 622-633
    • Nath, B.1    Szabo, G.2
  • 25
    • 77955856027 scopus 로고    scopus 로고
    • Endothelial adherens junctions and the actin cytoskeleton: an 'infinity net'?
    • PMID: 20377920
    • Lampugnani MG. Endothelial adherens junctions and the actin cytoskeleton: an 'infinity net'? J Biol 2010; 9: 16 [PMID: 20377920 DOI: 10.1186/jbiol232]
    • (2010) J Biol , vol.9 , pp. 16
    • Lampugnani, M.G.1
  • 26
    • 1842632667 scopus 로고    scopus 로고
    • Endothelial cell-cell junctions: happy together
    • PMID: 15071551
    • Dejana E. Endothelial cell-cell junctions: happy together. Nat Rev Mol Cell Biol 2004; 5: 261-270 [PMID: 15071551 DOI: 10.1038/ nrm1357]
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 261-270
    • Dejana, E.1
  • 27
    • 17244376204 scopus 로고    scopus 로고
    • Molecular basis of mechanical modulation of endothelial cell migration
    • PMID: 15769679
    • Chien S, Li S, Shiu YT, Li YS. Molecular basis of mechanical modulation of endothelial cell migration. Front Biosci 2005; 10:1985-2000 [PMID: 15769679 DOI: 10.2741/1673]
    • (2005) Front Biosci , vol.10 , pp. 1985-2000
    • Chien, S.1    Li, S.2    Shiu, Y.T.3    Li, Y.S.4
  • 28
    • 84875406320 scopus 로고    scopus 로고
    • Current concepts on the role of nitric oxide in portal hypertension
    • PMID: 23555159
    • Hu LS, George J, Wang JH. Current concepts on the role of nitric oxide in portal hypertension. World J Gastroenterol 2013; 19:1707-1717 [PMID: 23555159 DOI: 10.3748/wjg.v19.i11.1707]
    • (2013) World J Gastroenterol , vol.19 , pp. 1707-1717
    • Hu, L.S.1    George, J.2    Wang, J.H.3
  • 29
    • 84868486023 scopus 로고    scopus 로고
    • Angiopoietins in angiogenesis
    • PMID: 22922303
    • Fagiani E, Christofori G. Angiopoietins in angiogenesis. Cancer Lett 2013; 328: 18-26 [PMID: 22922303 DOI: 10.1016/ j.canlet.2012.08.018]
    • (2013) Cancer Lett , vol.328 , pp. 18-26
    • Fagiani, E.1    Christofori, G.2
  • 30
    • 84866183545 scopus 로고    scopus 로고
    • Matrix metalloproteinases in vascular physiology and disease
    • PMID:22896663
    • Siefert SA, Sarkar R. Matrix metalloproteinases in vascular physiology and disease. Vascular 2012; 20: 210-216 [PMID:22896663 DOI: 10.1258/vasc.2011.201202]
    • (2012) Vascular , vol.20 , pp. 210-216
    • Siefert, S.A.1    Sarkar, R.2
  • 31
    • 72949119124 scopus 로고    scopus 로고
    • Integrins in cancer: biological implications and therapeutic opportunities
    • PMID: 20029421
    • Desgrosellier JS, Cheresh DA. Integrins in cancer: biological implications and therapeutic opportunities. Nat Rev Cancer 2010; 10: 9-22 [PMID: 20029421 DOI: 10.1038/nrc2748]
    • (2010) Nat Rev Cancer , vol.10 , pp. 9-22
    • Desgrosellier, J.S.1    Cheresh, D.A.2
  • 32
    • 0036734093 scopus 로고    scopus 로고
    • A reevaluation of integrins as regulators of angiogenesis
    • PMID: 12205444
    • Hynes RO. A reevaluation of integrins as regulators of angiogenesis. Nat Med 2002; 8: 918-921 [PMID: 12205444 DOI:10.1038/nm0902-918]
    • (2002) Nat Med , vol.8 , pp. 918-921
    • Hynes, R.O.1
  • 33
    • 0035813126 scopus 로고    scopus 로고
    • Membrane type 1-matrix metalloproteinase is activated during migration of human endothelial cells and modulates endothelial motility and matrix remodeling
    • PMID: 11448964
    • Gálvez BG, Matías-Román S, Albar JP, Sánchez-Madrid F, Arroyo AG. Membrane type 1-matrix metalloproteinase is activated during migration of human endothelial cells and modulates endothelial motility and matrix remodeling. J Biol Chem 2001; 276:37491-37500 [PMID: 11448964 DOI: 10.1074/jbc.M104094200]
    • (2001) J Biol Chem , vol.276 , pp. 37491-37500
    • Gálvez, B.G.1    Matías-Román, S.2    Albar, J.P.3    Sánchez-Madrid, F.4    Arroyo, A.G.5
  • 34
    • 0037699954 scopus 로고    scopus 로고
    • The biology of VEGF and its receptors
    • PMID: 12778165
    • Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med 2003; 9: 669-676 [PMID: 12778165 DOI:10.1038/nm0603-669]
    • (2003) Nat Med , vol.9 , pp. 669-676
    • Ferrara, N.1    Gerber, H.P.2    LeCouter, J.3
  • 36
    • 84901630184 scopus 로고    scopus 로고
    • Angiogenic factors as potential drug target: efficacy and limitations of anti-angiogenic therapy
    • PMID: 24836679
    • Gacche RN, Meshram RJ. Angiogenic factors as potential drug target: efficacy and limitations of anti-angiogenic therapy. Biochim Biophys Acta 2014; 1846: 161-179 [PMID: 24836679 DOI:10.1016/j.bbcan.2014.05.002]
    • (2014) Biochim Biophys Acta , vol.1846 , pp. 161-179
    • Gacche, R.N.1    Meshram, R.J.2
  • 37
    • 33845529437 scopus 로고    scopus 로고
    • Pro-angiogenic cytokines and their role in tumor angiogenesis
    • PMID: 17006765
    • Neufeld G, Kessler O. Pro-angiogenic cytokines and their role in tumor angiogenesis. Cancer Metastasis Rev 2006; 25: 373-385 [PMID: 17006765 DOI: 10.1007/s10555-006-9011-5]
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 373-385
    • Neufeld, G.1    Kessler, O.2
  • 39
    • 84897428198 scopus 로고    scopus 로고
    • Neuropilins: role in signalling, angiogenesis and disease
    • PMID: 24217602
    • Zachary I. Neuropilins: role in signalling, angiogenesis and disease. Chem Immunol Allergy 2014; 99: 37-70 [PMID: 24217602 DOI: 10.1159/000354169]
    • (2014) Chem Immunol Allergy , vol.99 , pp. 37-70
    • Zachary, I.1
  • 40
    • 0038376002 scopus 로고    scopus 로고
    • Molecular regulation of vessel maturation
    • PMID: 12778167
    • Jain RK. Molecular regulation of vessel maturation. Nat Med 2003; 9: 685-693 [PMID: 12778167 DOI: 10.1038/nm0603-685]
    • (2003) Nat Med , vol.9 , pp. 685-693
    • Jain, R.K.1
  • 41
    • 0035972251 scopus 로고    scopus 로고
    • Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis
    • PMID: 11331305
    • Hellström M, Gerhardt H, Kalén M, Li X, Eriksson U, Wolburg H, Betsholtz C. Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol 2001; 153: 543-553 [PMID: 11331305 DOI: 10.1083/jcb.153.3.543]
    • (2001) J Cell Biol , vol.153 , pp. 543-553
    • Hellström, M.1    Gerhardt, H.2    Kalén, M.3    Li, X.4    Eriksson, U.5    Wolburg, H.6    Betsholtz, C.7
  • 42
    • 0037007226 scopus 로고    scopus 로고
    • Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors
    • PMID: 11927558
    • Goumans MJ, Valdimarsdottir G, Itoh S, Rosendahl A, Sideras P, ten Dijke P. Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors. EMBO J 2002; 21:1743-1753 [PMID: 11927558 DOI: 10.1093/emboj/21.7.1743]
    • (2002) EMBO J , vol.21 , pp. 1743-1753
    • Goumans, M.J.1    Valdimarsdottir, G.2    Itoh, S.3    Rosendahl, A.4    Sideras, P.5    ten Dijke, P.6
  • 44
    • 2342637066 scopus 로고    scopus 로고
    • Angiogenesis in chronic inflammatory liver disease
    • PMID: 15122744
    • Medina J, Arroyo AG, Sánchez-Madrid F, Moreno-Otero R. Angiogenesis in chronic inflammatory liver disease. Hepatology 2004; 39: 1185-1195 [PMID: 15122744 DOI: 10.1002/hep.20193]
    • (2004) Hepatology , vol.39 , pp. 1185-1195
    • Medina, J.1    Arroyo, A.G.2    Sánchez-Madrid, F.3    Moreno-Otero, R.4
  • 46
    • 79751508907 scopus 로고    scopus 로고
    • Angiopoietin-like proteins:emerging targets for treatment of obesity and related metabolic diseases
    • PMID: 21182596
    • Kadomatsu T, Tabata M, Oike Y. Angiopoietin-like proteins:emerging targets for treatment of obesity and related metabolic diseases. FEBS J 2011; 278: 559-564 [PMID: 21182596 DOI:10.1111/j.1742-4658.2010.07979.x]
    • (2011) FEBS J , vol.278 , pp. 559-564
    • Kadomatsu, T.1    Tabata, M.2    Oike, Y.3
  • 47
    • 34447106967 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha expression in experimental cirrhosis: correlation with vascular endothelial growth factor expression and angiogenesis
    • PMID: 17614845
    • Bozova S, Elpek GO. Hypoxia-inducible factor-1alpha expression in experimental cirrhosis: correlation with vascular endothelial growth factor expression and angiogenesis. APMIS 2007; 115:795-801 [PMID: 17614845 DOI: 10.1111/j.1600-0463.2007. apm_610.x]
    • (2007) APMIS , vol.115 , pp. 795-801
    • Bozova, S.1    Elpek, G.O.2
  • 48
    • 84875259878 scopus 로고    scopus 로고
    • Angiogenesis: a phenomenon which aggravates chronic liver disease progression
    • Kukla M. Angiogenesis: a phenomenon which aggravates chronic liver disease progression. Hepatology Int 2013; 7: 4-12 [DOI:10.1007/s12072-012-9391-2]
    • (2013) Hepatology Int , vol.7 , pp. 4-12
    • Kukla, M.1
  • 49
    • 39749170639 scopus 로고    scopus 로고
    • Myofibroblast - like cells and liver fibrogenesis: Emerging concepts in a rapidly moving scenario
    • PMID: 18022682
    • Parola M, Marra F, Pinzani M. Myofibroblast - like cells and liver fibrogenesis: Emerging concepts in a rapidly moving scenario. Mol Aspects Med 2008; 29: 58-66 [PMID: 18022682 DOI: 10.1016/ j.mam.2007.09.002]
    • (2008) Mol Aspects Med , vol.29 , pp. 58-66
    • Parola, M.1    Marra, F.2    Pinzani, M.3
  • 50
    • 3543098600 scopus 로고    scopus 로고
    • Liver fibrosis: from the bench to clinical targets
    • PMID: 15115333
    • Pinzani M, Rombouts K. Liver fibrosis: from the bench to clinical targets. Dig Liver Dis 2004; 36: 231-242 [PMID: 15115333 DOI:10.1016/j.dld.2004.01.003]
    • (2004) Dig Liver Dis , vol.36 , pp. 231-242
    • Pinzani, M.1    Rombouts, K.2
  • 52
    • 75149195964 scopus 로고    scopus 로고
    • Detection of characteristic sub pathway network for angiogenesis based on the comprehensive pathway network
    • PMID: 20122205
    • Huang Y, Li S. Detection of characteristic sub pathway network for angiogenesis based on the comprehensive pathway network. BMC Bioinformatics 2010; 11 Suppl 1: S32 [PMID: 20122205 DOI:10.1186/1471-2105-11-S1-S32]
    • (2010) BMC Bioinformatics , vol.11 , pp. S32
    • Huang, Y.1    Li, S.2
  • 53
    • 44349157832 scopus 로고    scopus 로고
    • Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
    • PMID: 18500244
    • Dewhirst MW, Cao Y, Moeller B. Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response. Nat Rev Cancer 2008; 8: 425-437 [PMID: 18500244 DOI: 10.1038/nrc2397]
    • (2008) Nat Rev Cancer , vol.8 , pp. 425-437
    • Dewhirst, M.W.1    Cao, Y.2    Moeller, B.3
  • 54
  • 56
    • 33846980834 scopus 로고    scopus 로고
    • The complex functions of mast cells in chronic human liver diseases
    • PMID: 17103041
    • Franceschini B, Ceva-Grimaldi G, Russo C, Dioguardi N, Grizzi F. The complex functions of mast cells in chronic human liver diseases. Dig Dis Sci 2006; 51: 2248-2256 [PMID: 17103041 DOI:10.1007/s10620-006-9082-8]
    • (2006) Dig Dis Sci , vol.51 , pp. 2248-2256
    • Franceschini, B.1    Ceva-Grimaldi, G.2    Russo, C.3    Dioguardi, N.4    Grizzi, F.5
  • 57
    • 32244447827 scopus 로고    scopus 로고
    • Angiogenesis and inflammation face off
    • PMID: 16462798
    • Imhof BA, Aurrand-Lions M. Angiogenesis and inflammation face off. Nat Med 2006; 12: 171-172 [PMID: 16462798 DOI: 10.1038/ nm0206-171]
    • (2006) Nat Med , vol.12 , pp. 171-172
    • Imhof, B.A.1    Aurrand-Lions, M.2
  • 58
    • 4444289142 scopus 로고    scopus 로고
    • Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes
    • PMID: 15362042
    • Safadi R, Ohta M, Alvarez CE, Fiel MI, Bansal M, Mehal WZ, Friedman SL. Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes. Gastroenterology 2004; 127: 870-882 [PMID: 15362042 DOI:10.1053/j.gastro.2004.04.062]
    • (2004) Gastroenterology , vol.127 , pp. 870-882
    • Safadi, R.1    Ohta, M.2    Alvarez, C.E.3    Fiel, M.I.4    Bansal, M.5    Mehal, W.Z.6    Friedman, S.L.7
  • 59
    • 15244356690 scopus 로고    scopus 로고
    • Mechanisms of disease: Mechanisms of hepatic fibrosis and therapeutic implications
    • PMID: 16265071
    • Friedman SL. Mechanisms of disease: Mechanisms of hepatic fibrosis and therapeutic implications. Nat Clin Pract Gastroenterol Hepatol 2004; 1: 98-105 [PMID: 16265071 DOI: 10.1038/ ncpgasthep0055]
    • (2004) Nat Clin Pract Gastroenterol Hepatol , vol.1 , pp. 98-105
    • Friedman, S.L.1
  • 61
    • 33747611690 scopus 로고    scopus 로고
    • Transcriptional regulation of stellate cell activation
    • PMID:16958680
    • Friedman SL. Transcriptional regulation of stellate cell activation. J Gastroenterol Hepatol 2006; 21 Suppl 3: S79-S83 [PMID:16958680 DOI: 10.1111/j.1440-1746.2006.04585.x]
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. S79-S83
    • Friedman, S.L.1
  • 62
    • 1842426689 scopus 로고    scopus 로고
    • Regulatory role of vHL/HIF-1alpha in hypoxia-induced VEGF production in hepatic stellate cells
    • PMID: 15063765
    • Wang YQ, Luk JM, Ikeda K, Man K, Chu AC, Kaneda K, Fan ST. Regulatory role of vHL/HIF-1alpha in hypoxia-induced VEGF production in hepatic stellate cells. Biochem Biophys Res Commun 2004; 317: 358-362 [PMID: 15063765 DOI: 10.1016/ j.bbrc.2004.03.050]
    • (2004) Biochem Biophys Res Commun , vol.317 , pp. 358-362
    • Wang, Y.Q.1    Luk, J.M.2    Ikeda, K.3    Man, K.4    Chu, A.C.5    Kaneda, K.6    Fan, S.T.7
  • 63
    • 84892553453 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ interrupts angiogenic signal transduction by transrepression of platelet-derived growth factor-β receptor in hepatic stellate cells
    • PMID: 24259663
    • Zhang F, Kong D, Chen L, Zhang X, Lian N, Zhu X, Lu Y, Zheng S. Peroxisome proliferator-activated receptor-γ interrupts angiogenic signal transduction by transrepression of platelet-derived growth factor-β receptor in hepatic stellate cells. J Cell Sci 2014; 127:305-314 [PMID: 24259663 DOI: 10.1242/jcs.128306]
    • (2014) J Cell Sci , vol.127 , pp. 305-314
    • Zhang, F.1    Kong, D.2    Chen, L.3    Zhang, X.4    Lian, N.5    Zhu, X.6    Lu, Y.7    Zheng, S.8
  • 65
    • 84877015934 scopus 로고    scopus 로고
    • Chemokines in tissue fibrosis
    • PMID: 23159607
    • Sahin H, Wasmuth HE. Chemokines in tissue fibrosis. Biochim Biophys Acta 2013; 1832: 1041-1048 [PMID: 23159607 DOI:10.1016/j.bbadis.2012.11.004]
    • (2013) Biochim Biophys Acta , vol.1832 , pp. 1041-1048
    • Sahin, H.1    Wasmuth, H.E.2
  • 66
    • 55449105228 scopus 로고    scopus 로고
    • Chemokines as mediators of neovascularization
    • PMID: 18757292
    • Keeley EC, Mehrad B, Strieter RM. Chemokines as mediators of neovascularization. Arterioscler Thromb Vasc Biol 2008; 28:1928-1936 [PMID: 18757292 DOI: 10.1161/ATVBAHA.108.162925]
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1928-1936
    • Keeley, E.C.1    Mehrad, B.2    Strieter, R.M.3
  • 68
    • 4344688204 scopus 로고    scopus 로고
    • Platelet factor 4 disrupts the intracellular signalling cascade induced by vascular endothelial growth factor by both KDR dependent and independent mechanisms
    • PMID: 15291808
    • Sulpice E, Contreres JO, Lacour J, Bryckaert M, Tobelem G. Platelet factor 4 disrupts the intracellular signalling cascade induced by vascular endothelial growth factor by both KDR dependent and independent mechanisms. Eur J Biochem 2004; 271: 3310-3318 [PMID: 15291808 DOI: 10.1111/j.1432-1033.2004.04263.x]
    • (2004) Eur J Biochem , vol.271 , pp. 3310-3318
    • Sulpice, E.1    Contreres, J.O.2    Lacour, J.3    Bryckaert, M.4    Tobelem, G.5
  • 74
    • 42349084337 scopus 로고    scopus 로고
    • Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signalling pathways: novel insights into visfatin-induced angiogenesis
    • PMID: 18093986
    • Adya R, Tan BK, Punn A, Chen J, Randeva HS. Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signalling pathways: novel insights into visfatin-induced angiogenesis. Cardiovasc Res 2008; 78: 356-365 [PMID: 18093986 DOI: 10.1093/cvr/cvm111]
    • (2008) Cardiovasc Res , vol.78 , pp. 356-365
    • Adya, R.1    Tan, B.K.2    Punn, A.3    Chen, J.4    Randeva, H.S.5
  • 75
    • 74749094447 scopus 로고    scopus 로고
    • Identification of chemerin receptor (ChemR23) in human endothelial cells:chemerin-induced endothelial angiogenesis
    • PMID: 20044979
    • Kaur J, Adya R, Tan BK, Chen J, Randeva HS. Identification of chemerin receptor (ChemR23) in human endothelial cells:chemerin-induced endothelial angiogenesis. Biochem Biophys Res Commun 2010; 391: 1762-1768 [PMID: 20044979 DOI: 10.1016/ j.bbrc.2009.12.150]
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 1762-1768
    • Kaur, J.1    Adya, R.2    Tan, B.K.3    Chen, J.4    Randeva, H.S.5
  • 76
    • 57249115900 scopus 로고    scopus 로고
    • Induction of angiogenesis by murine resistin: putative role of PI3-kinase and NO-dependent pathways
    • PMID: 18722482
    • Robertson SA, Rae CJ, Graham A. Induction of angiogenesis by murine resistin: putative role of PI3-kinase and NO-dependent pathways. Regul Pept 2009; 152: 41-47 [PMID: 18722482 DOI:10.1016/j.regpep.2008.07.008]
    • (2009) Regul Pept , vol.152 , pp. 41-47
    • Robertson, S.A.1    Rae, C.J.2    Graham, A.3
  • 77
    • 1442354888 scopus 로고    scopus 로고
    • Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis
    • PMID: 14983034
    • Bråkenhielm E, Veitonmäki N, Cao R, Kihara S, Matsuzawa Y, Zhivotovsky B, Funahashi T, Cao Y. Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis. Proc Natl Acad Sci USA 2004; 101:2476-2481 [PMID: 14983034 DOI: 10.1073/pnas.0308671100]
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 2476-2481
    • Bråkenhielm, E.1    Veitonmäki, N.2    Cao, R.3    Kihara, S.4    Matsuzawa, Y.5    Zhivotovsky, B.6    Funahashi, T.7    Cao, Y.8
  • 78
    • 82855168116 scopus 로고    scopus 로고
    • Potential role of leptin, adiponectin and three novel adipokines--visfatin, chemerin and vaspin--in chronic hepatitis
    • PMID: 21738955
    • Kukla M, Mazur W, Bułdak RJ, Zwirska-Korczala K. Potential role of leptin, adiponectin and three novel adipokines--visfatin, chemerin and vaspin--in chronic hepatitis. Mol Med 2011; 17: 1397-1410 [PMID: 21738955 DOI: 10.2119/molmed.2010.00105]
    • (2011) Mol Med , vol.17 , pp. 1397-1410
    • Kukla, M.1    Mazur, W.2    Bułdak, R.J.3    Zwirska-Korczala, K.4
  • 79
    • 48349147074 scopus 로고    scopus 로고
    • The role of adipokines in liver fibrosis
    • PMID: 18602801
    • Bertolani C, Marra F. The role of adipokines in liver fibrosis. Pathophysiology 2008; 15: 91-101 [PMID: 18602801 DOI:10.1016/j.pathophys.2008.05.001]
    • (2008) Pathophysiology , vol.15 , pp. 91-101
    • Bertolani, C.1    Marra, F.2
  • 80
    • 84869861336 scopus 로고    scopus 로고
    • Functional and structural features of adipokine family
    • PMID: 23022179
    • Raucci R, Rusolo F, Sharma A, Colonna G, Castello G, Costantini S. Functional and structural features of adipokine family. Cytokine 2013; 61: 1-14 [PMID: 23022179 DOI: 10.1016/j.cyto.2012.08.036]
    • (2013) Cytokine , vol.61 , pp. 1-14
    • Raucci, R.1    Rusolo, F.2    Sharma, A.3    Colonna, G.4    Castello, G.5    Costantini, S.6
  • 81
    • 70349980165 scopus 로고    scopus 로고
    • Vaspin can not inhibit TNF-alpha-induced inflammation of human umbilical vein endothelial cells
    • PMID:19801900
    • Fu BD, Yamawaki H, Okada M, Hara Y. Vaspin can not inhibit TNF-alpha-induced inflammation of human umbilical vein endothelial cells. J Vet Med Sci 2009; 71: 1201-1207 [PMID:19801900 DOI: 10.1292/jvms.71.1201]
    • (2009) J Vet Med Sci , vol.71 , pp. 1201-1207
    • Fu, B.D.1    Yamawaki, H.2    Okada, M.3    Hara, Y.4
  • 83
    • 77950343252 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
    • PMID: 20303879
    • Hotamisligil GS. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 2010; 140: 900-917 [PMID: 20303879 DOI: 10.1016/j.cell.2010.02.034]
    • (2010) Cell , vol.140 , pp. 900-917
    • Hotamisligil, G.S.1
  • 87
    • 67349196781 scopus 로고    scopus 로고
    • Elevated hepatic iron: a confounding factor in chronic hepatitis C
    • PMID: 19393721
    • Isom HC, McDevitt EI, Moon MS. Elevated hepatic iron: a confounding factor in chronic hepatitis C. Biochim Biophys Acta 2009; 1790: 650-662 [PMID: 19393721 DOI: 10.1016/ j.bbagen.2009.04.009]
    • (2009) Biochim Biophys Acta , vol.1790 , pp. 650-662
    • Isom, H.C.1    McDevitt, E.I.2    Moon, M.S.3
  • 90
    • 79952708723 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in liver disease
    • PMID: 21145844
    • Malhi H, Kaufman RJ. Endoplasmic reticulum stress in liver disease. J Hepatol 2011; 54: 795-809 [PMID: 21145844 DOI:10.1016/j.jhep.2010.11.005]
    • (2011) J Hepatol , vol.54 , pp. 795-809
    • Malhi, H.1    Kaufman, R.J.2
  • 91
    • 80052003590 scopus 로고    scopus 로고
    • Primary prophylaxis against gastric variceal bleeding:is there a sticky solution at last?
    • PMID: 22179988
    • Tripathi D. Primary prophylaxis against gastric variceal bleeding:is there a sticky solution at last? Hepatology 2011; 54: 1094-1096 [PMID: 22179988 DOI: 10.1002/hep.24499]
    • (2011) Hepatology , vol.54 , pp. 1094-1096
    • Tripathi, D.1
  • 92
    • 84901011336 scopus 로고    scopus 로고
    • Neuropilin regulation of angiogenesis, arteriogenesis, and vascular permeability
    • PMID: 24521511
    • Plein A, Fantin A, Ruhrberg C. Neuropilin regulation of angiogenesis, arteriogenesis, and vascular permeability. Microcirculation 2014; 21:315-323 [PMID: 24521511 DOI: 10.1111/micc.12124]
    • (2014) Microcirculation , vol.21 , pp. 315-323
    • Plein, A.1    Fantin, A.2    Ruhrberg, C.3
  • 94
    • 80051990926 scopus 로고    scopus 로고
    • Neuropilin and liver fibrosis: hitting three birds with one stone?
    • PMID:22179987
    • Troeger JS, Schwabe RF. Neuropilin and liver fibrosis: hitting three birds with one stone? Hepatology 2011; 54: 1091-1093 [PMID:22179987 DOI: 10.1002/hep.24484]
    • (2011) Hepatology , vol.54 , pp. 1091-1093
    • Troeger, J.S.1    Schwabe, R.F.2
  • 97
    • 4043169060 scopus 로고    scopus 로고
    • Microvessel density and clinicopathological characteristics in hepatitis C virus and hepatitis B virus related hepatocellular carcinoma
    • PMID: 15280410
    • Messerini L, Novelli L, Comin CE. Microvessel density and clinicopathological characteristics in hepatitis C virus and hepatitis B virus related hepatocellular carcinoma. J Clin Pathol 2004; 57:867-871 [PMID: 15280410 DOI: 10.1136/jcp.2003.015784]
    • (2004) J Clin Pathol , vol.57 , pp. 867-871
    • Messerini, L.1    Novelli, L.2    Comin, C.E.3
  • 98
    • 34848880488 scopus 로고    scopus 로고
    • Liver angiogenesis as a risk factor for hepatocellular carcinoma development in hepatitis C virus cirrhotic patients
    • PMID: 17854145
    • Mazzanti R, Messerini L, Comin CE, Fedeli L, Ganne-Carrie N, Beaugrand M. Liver angiogenesis as a risk factor for hepatocellular carcinoma development in hepatitis C virus cirrhotic patients. World J Gastroenterol 2007; 13: 5009-5014 [PMID: 17854145]
    • (2007) World J Gastroenterol , vol.13 , pp. 5009-5014
    • Mazzanti, R.1    Messerini, L.2    Comin, C.E.3    Fedeli, L.4    Ganne-Carrie, N.5    Beaugrand, M.6
  • 99
    • 71749116710 scopus 로고    scopus 로고
    • Leptin, neopterin and hepatocyte growth factor as markers of fibrosis and inflammatory activity in chronic hepatitis C
    • Zwirska-Korczala K, Kukla M, Ziołkowski A. Leptin, neopterin and hepatocyte growth factor as markers of fibrosis and inflammatory activity in chronic hepatitis C. Exp Clin Hep 2005; 1:60-65
    • (2005) Exp Clin Hep , vol.1 , pp. 60-65
    • Zwirska-Korczala, K.1    Kukla, M.2    Ziołkowski, A.3
  • 102
    • 84860644762 scopus 로고    scopus 로고
    • Angiogenic activity of hepatitis B and C viruses
    • PMID: 22182803
    • Vrancken K, Paeshuyse J, Liekens S. Angiogenic activity of hepatitis B and C viruses. Antivir Chem Chemother 2012; 22:159-170 [PMID: 22182803 DOI: 10.3851/IMP1987]
    • (2012) Antivir Chem Chemother , vol.22 , pp. 159-170
    • Vrancken, K.1    Paeshuyse, J.2    Liekens, S.3
  • 103
    • 84901596453 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 and its role in viral carcinogenesis
    • PMID: 24698149
    • Cuninghame S, Jackson R, Zehbe I. Hypoxia-inducible factor 1 and its role in viral carcinogenesis. Virology 2014; 456-457:370-383 [PMID: 24698149 DOI: 10.1016/j.virol.2014.02.027]
    • (2014) Virology , vol.456-457 , pp. 370-383
    • Cuninghame, S.1    Jackson, R.2    Zehbe, I.3
  • 104
    • 34648830896 scopus 로고    scopus 로고
    • Hepatitis C virus stabilizes hypoxia-inducible factor 1alpha and stimulates the synthesis of vascular endothelial growth factor
    • PMID: 17626077
    • Nasimuzzaman M, Waris G, Mikolon D, Stupack DG, Siddiqui A. Hepatitis C virus stabilizes hypoxia-inducible factor 1alpha and stimulates the synthesis of vascular endothelial growth factor. J Virol 2007; 81: 10249-10257 [PMID: 17626077 DOI: 10.1128/ JVI.00763-07]
    • (2007) J Virol , vol.81 , pp. 10249-10257
    • Nasimuzzaman, M.1    Waris, G.2    Mikolon, D.3    Stupack, D.G.4    Siddiqui, A.5
  • 105
    • 16244405250 scopus 로고    scopus 로고
    • Hepatitis C virus, ER stress, and oxidative stress
    • PMID:15817385
    • Tardif KD, Waris G, Siddiqui A. Hepatitis C virus, ER stress, and oxidative stress. Trends Microbiol 2005; 13: 159-163 [PMID:15817385 DOI: 10.1016/j.tim.2005.02.004]
    • (2005) Trends Microbiol , vol.13 , pp. 159-163
    • Tardif, K.D.1    Waris, G.2    Siddiqui, A.3
  • 106
    • 84860683318 scopus 로고    scopus 로고
    • Hepatitis C virus core protein upregulates the expression of vascular endothelial growth factor via the nuclear factor-κB/hypoxia-inducible factor-1α axis under hypoxic conditions
    • PMID:22221855
    • Abe M, Koga H, Yoshida T, Masuda H, Iwamoto H, Sakata M, Hanada S, Nakamura T, Taniguchi E, Kawaguchi T, Yano H, Torimura T, Ueno T, Sata M. Hepatitis C virus core protein upregulates the expression of vascular endothelial growth factor via the nuclear factor-κB/hypoxia-inducible factor-1α axis under hypoxic conditions. Hepatol Res 2012; 42: 591-600 [PMID:22221855 DOI: 10.1111/j.1872-034X.2011.00953.x]
    • (2012) Hepatol Res , vol.42 , pp. 591-600
    • Abe, M.1    Koga, H.2    Yoshida, T.3    Masuda, H.4    Iwamoto, H.5    Sakata, M.6    Hanada, S.7    Nakamura, T.8    Taniguchi, E.9    Kawaguchi, T.10    Yano, H.11    Torimura, T.12    Ueno, T.13    Sata, M.14
  • 109
    • 77249149954 scopus 로고    scopus 로고
    • Hepatitis C virus infection reduces hepatocellular polarity in a vascular endothelial growth factor-dependent manner
    • PMID: 19944696
    • Mee CJ, Farquhar MJ, Harris HJ, Hu K, Ramma W, Ahmed A, Maurel P, Bicknell R, Balfe P, McKeating JA. Hepatitis C virus infection reduces hepatocellular polarity in a vascular endothelial growth factor-dependent manner. Gastroenterology 2010; 138:1134-1142 [PMID: 19944696 DOI: 10.1053/j.gastro.2009.11.047]
    • (2010) Gastroenterology , vol.138 , pp. 1134-1142
    • Mee, C.J.1    Farquhar, M.J.2    Harris, H.J.3    Hu, K.4    Ramma, W.5    Ahmed, A.6    Maurel, P.7    Bicknell, R.8    Balfe, P.9    McKeating, J.A.10
  • 110
    • 66149084790 scopus 로고    scopus 로고
    • Hepatitis C virus core protein triggers hepatic angiogenesis by a mechanism including multiple pathways
    • PMID: 19235829
    • Hassan M, Selimovic D, Ghozlan H, Abdel-kader O. Hepatitis C virus core protein triggers hepatic angiogenesis by a mechanism including multiple pathways. Hepatology 2009; 49: 1469-1482 [PMID: 19235829 DOI: 10.1002/hep.22849]
    • (2009) Hepatology , vol.49 , pp. 1469-1482
    • Hassan, M.1    Selimovic, D.2    Ghozlan, H.3    Abdel-kader, O.4
  • 111
    • 79251516703 scopus 로고    scopus 로고
    • Regulation of mucosal addressin cell adhesion molecule 1 expression in human and mice by vascular adhesion protein 1 amine oxidase activity
    • PMID: 21225644
    • Liaskou E, Karikoski M, Reynolds GM, Lalor PF, Weston CJ, Pullen N, Salmi M, Jalkanen S, Adams DH. Regulation of mucosal addressin cell adhesion molecule 1 expression in human and mice by vascular adhesion protein 1 amine oxidase activity. Hepatology 2011; 53: 661-672 [PMID: 21225644 DOI: 10.1002/hep.24085]
    • (2011) Hepatology , vol.53 , pp. 661-672
    • Liaskou, E.1    Karikoski, M.2    Reynolds, G.M.3    Lalor, P.F.4    Weston, C.J.5    Pullen, N.6    Salmi, M.7    Jalkanen, S.8    Adams, D.H.9
  • 116
    • 84870523040 scopus 로고    scopus 로고
    • Differential functions of C- and N-terminal hepatitis B x protein in liver cells treated with doxorubicin in normoxic or hypoxic condition
    • PMID: 23209654
    • Chau DK, Chen GG, Zhang H, Leung BC, Chun S, Lai PB. Differential functions of C- and N-terminal hepatitis B x protein in liver cells treated with doxorubicin in normoxic or hypoxic condition. PLoS One 2012; 7: e50118 [PMID: 23209654 DOI:10.1371/journal.pone.0050118]
    • (2012) PLoS One , vol.7 , pp. e50118
    • Chau, D.K.1    Chen, G.G.2    Zhang, H.3    Leung, B.C.4    Chun, S.5    Lai, P.B.6
  • 117
    • 84864587705 scopus 로고    scopus 로고
    • Hepatitis B virus X protein upregulates mTOR signaling through IKKβ to increase cell proliferation and VEGF production in hepatocellular carcinoma
    • PMID: 22848663
    • Yen CJ, Lin YJ, Yen CS, Tsai HW, Tsai TF, Chang KY, Huang WC, Lin PW, Chiang CW, Chang TT. Hepatitis B virus X protein upregulates mTOR signaling through IKKβ to increase cell proliferation and VEGF production in hepatocellular carcinoma. PLoS One 2012; 7: e41931 [PMID: 22848663 DOI: 10.1371/ journal.pone.0041931.]
    • (2012) PLoS One , vol.7 , pp. e41931
    • Yen, C.J.1    Lin, Y.J.2    Yen, C.S.3    Tsai, H.W.4    Tsai, T.F.5    Chang, K.Y.6    Huang, W.C.7    Lin, P.W.8    Chiang, C.W.9    Chang, T.T.10
  • 118
    • 79956014865 scopus 로고    scopus 로고
    • The purpose of the HIF-1/PHD feedback loop: to limit mTOR-induced HIF-1α
    • PMID: 21521942
    • Demidenko ZN, Blagosklonny MV. The purpose of the HIF-1/PHD feedback loop: to limit mTOR-induced HIF-1α. Cell Cycle 2011; 10: 1557-1562 [PMID: 21521942 DOI: 10.4161/cc.10.10.15789]
    • (2011) Cell Cycle , vol.10 , pp. 1557-1562
    • Demidenko, Z.N.1    Blagosklonny, M.V.2
  • 120
    • 40849145756 scopus 로고    scopus 로고
    • The management of portal hypertension: rational basis, available treatments and future options
    • PMID: 18304681
    • Bosch J, Berzigotti A, Garcia-Pagan JC, Abraldes JG. The management of portal hypertension: rational basis, available treatments and future options. J Hepatol 2008; 48 Suppl 1: S68-S92 [PMID: 18304681 DOI: 10.1016/j.jhep.2008.01.021]
    • (2008) J Hepatol , vol.48 , pp. S68-S92
    • Bosch, J.1    Berzigotti, A.2    Garcia-Pagan, J.C.3    Abraldes, J.G.4
  • 121
    • 1542347683 scopus 로고    scopus 로고
    • Anti-VEGF receptor-2 monoclonal antibody prevents portalsystemic collateral vessel formation in portal hypertensive mice
    • PMID: 14988842
    • Fernandez M, Vizzutti F, Garcia-Pagan JC, Rodes J, Bosch J. Anti-VEGF receptor-2 monoclonal antibody prevents portalsystemic collateral vessel formation in portal hypertensive mice. Gastroenterology 2004; 126: 886-894 [PMID: 14988842 DOI:10.1053/j.gastro.2003.12.012]
    • (2004) Gastroenterology , vol.126 , pp. 886-894
    • Fernandez, M.1    Vizzutti, F.2    Garcia-Pagan, J.C.3    Rodes, J.4    Bosch, J.5
  • 122
    • 77955853856 scopus 로고    scopus 로고
    • Hepatic endothelial dysfunction and abnormal angiogenesis: new targets in the treatment of portal hypertension
    • PMID: 20561700
    • Bosch J, Abraldes JG, Fernández M, García-Pagán JC. Hepatic endothelial dysfunction and abnormal angiogenesis: new targets in the treatment of portal hypertension. J Hepatol 2010; 53: 558-567 [PMID: 20561700 DOI: 10.1016/j.jhep.2010.03.021]
    • (2010) J Hepatol , vol.53 , pp. 558-567
    • Bosch, J.1    Abraldes, J.G.2    Fernández, M.3    García-Pagán, J.C.4
  • 124
    • 65449130742 scopus 로고    scopus 로고
    • Beneficial effects of sorafenib on splanchnic, intrahepatic, and portocollateral circulations in portal hypertensive and cirrhotic rats
    • PMID: 19137587
    • Mejias M, Garcia-Pras E, Tiani C, Miquel R, Bosch J, Fernandez M. Beneficial effects of sorafenib on splanchnic, intrahepatic, and portocollateral circulations in portal hypertensive and cirrhotic rats. Hepatology 2009; 49: 1245-1256 [PMID: 19137587 DOI: 10.1002/ hep.22758]
    • (2009) Hepatology , vol.49 , pp. 1245-1256
    • Mejias, M.1    Garcia-Pras, E.2    Tiani, C.3    Miquel, R.4    Bosch, J.5    Fernandez, M.6
  • 125
    • 33645240442 scopus 로고    scopus 로고
    • Ascorbic acid improves the intrahepatic endothelial dysfunction of patients with cirrhosis and portal hypertension
    • PMID:16496307
    • Hernández-Guerra M, García-Pagán JC, Turnes J, Bellot P, Deulofeu R, Abraldes JG, Bosch J. Ascorbic acid improves the intrahepatic endothelial dysfunction of patients with cirrhosis and portal hypertension. Hepatology 2006; 43: 485-491 [PMID:16496307 DOI: 10.1002/hep.21080]
    • (2006) Hepatology , vol.43 , pp. 485-491
    • Hernández-Guerra, M.1    García-Pagán, J.C.2    Turnes, J.3    Bellot, P.4    Deulofeu, R.5    Abraldes, J.G.6    Bosch, J.7
  • 126
    • 33745941120 scopus 로고    scopus 로고
    • The eNOS cofactor tetrahydrobiopterin improves endothelial dysfunction in livers of rats with CCl4 cirrhosis
    • PMID:16799985
    • Matei V, Rodríguez-Vilarrupla A, Deulofeu R, Colomer D, Fernández M, Bosch J, Garcia-Pagán JC. The eNOS cofactor tetrahydrobiopterin improves endothelial dysfunction in livers of rats with CCl4 cirrhosis. Hepatology 2006; 44: 44-52 [PMID:16799985 DOI: 10.1002/hep.21228]
    • (2006) Hepatology , vol.44 , pp. 44-52
    • Matei, V.1    Rodríguez-Vilarrupla, A.2    Deulofeu, R.3    Colomer, D.4    Fernández, M.5    Bosch, J.6    Garcia-Pagán, J.C.7
  • 127
    • 79952438097 scopus 로고    scopus 로고
    • Hemodynamic assessment of the development of portal-systemic collaterals in portal hypertensive rats
    • PMID:20635149
    • Chan CC, Tsai SC, Cheng LY, Lee FY, Lin HC. Hemodynamic assessment of the development of portal-systemic collaterals in portal hypertensive rats. Dig Dis Sci 2011; 56: 417-424 [PMID:20635149 DOI: 10.1007/s10620-010-1302-6]
    • (2011) Dig Dis Sci , vol.56 , pp. 417-424
    • Chan, C.C.1    Tsai, S.C.2    Cheng, L.Y.3    Lee, F.Y.4    Lin, H.C.5
  • 128
    • 53349156840 scopus 로고    scopus 로고
    • Rapamycin prevents mesenteric neo-angiogenesis and reduces splanchnic blood flow in portal hypertensive mice
    • PMID:18564143
    • Geerts AM, Vanheule E, Van Vlierberghe H, Leybaert L, Van Steenkiste C, De Vos M, Colle I. Rapamycin prevents mesenteric neo-angiogenesis and reduces splanchnic blood flow in portal hypertensive mice. Hepatol Res 2008; 38: 1130-1139 [PMID:18564143 DOI: 10.1111/j.1872-034X.2008.00369.x]
    • (2008) Hepatol Res , vol.38 , pp. 1130-1139
    • Geerts, A.M.1    Vanheule, E.2    Van Vlierberghe, H.3    Leybaert, L.4    Van Steenkiste, C.5    De Vos, M.6    Colle, I.7
  • 130
    • 84863520977 scopus 로고    scopus 로고
    • Cannabinoid receptor 2 agonist ameliorates mesenteric angiogenesis and portosystemic collaterals in cirrhotic rats
    • PMID:22290687
    • Huang HC, Wang SS, Hsin IF, Chang CC, Lee FY, Lin HC, Chuang CL, Lee JY, Hsieh HG, Lee SD. Cannabinoid receptor 2 agonist ameliorates mesenteric angiogenesis and portosystemic collaterals in cirrhotic rats. Hepatology 2012; 56: 248-258 [PMID:22290687 DOI: 10.1002/hep.25625]
    • (2012) Hepatology , vol.56 , pp. 248-258
    • Huang, H.C.1    Wang, S.S.2    Hsin, I.F.3    Chang, C.C.4    Lee, F.Y.5    Lin, H.C.6    Chuang, C.L.7    Lee, J.Y.8    Hsieh, H.G.9    Lee, S.D.10
  • 131
    • 66749106254 scopus 로고    scopus 로고
    • Epidemiology and natural history of nonalcoholic fatty liver disease (NAFLD)
    • PMID: 19381118
    • Bellentani S, Marino M. Epidemiology and natural history of nonalcoholic fatty liver disease (NAFLD). Ann Hepatol 2009; 8 Suppl 1:S4-S8 [PMID: 19381118]
    • (2009) Ann Hepatol , vol.8 , pp. S4-S8
    • Bellentani, S.1    Marino, M.2
  • 132
    • 40149088797 scopus 로고    scopus 로고
    • The blind men 'see' the elephant-the many faces of fatty liver disease
    • PMID:18240340
    • Sanal MG. The blind men 'see' the elephant-the many faces of fatty liver disease. World J Gastroenterol 2008; 14: 831-844 [PMID:18240340 DOI: 10.3748/wjg.14.831]
    • (2008) World J Gastroenterol , vol.14 , pp. 831-844
    • Sanal, M.G.1
  • 133
    • 4043170647 scopus 로고    scopus 로고
    • Hepatic microvascular dysfunction during evolution of dietary steatohepatitis in mice
    • PMID: 15368443
    • McCuskey RS, Ito Y, Robertson GR, McCuskey MK, Perry M, Farrell GC. Hepatic microvascular dysfunction during evolution of dietary steatohepatitis in mice. Hepatology 2004; 40: 386-393 [PMID: 15368443 DOI: 10.1002/hep.20302]
    • (2004) Hepatology , vol.40 , pp. 386-393
    • McCuskey, R.S.1    Ito, Y.2    Robertson, G.R.3    McCuskey, M.K.4    Perry, M.5    Farrell, G.C.6
  • 135
    • 79960745146 scopus 로고    scopus 로고
    • Hypoxia-inducible transcription factor 2α promotes steatohepatitis through augmenting lipid accumulation, inflammation, and fibrosis
    • PMID:21538443
    • Qu A, Taylor M, Xue X, Matsubara T, Metzger D, Chambon P, Gonzalez FJ, Shah YM. Hypoxia-inducible transcription factor 2α promotes steatohepatitis through augmenting lipid accumulation, inflammation, and fibrosis. Hepatology 2011; 54: 472-483 [PMID:21538443 DOI: 10.1002/hep.24400]
    • (2011) Hepatology , vol.54 , pp. 472-483
    • Qu, A.1    Taylor, M.2    Xue, X.3    Matsubara, T.4    Metzger, D.5    Chambon, P.6    Gonzalez, F.J.7    Shah, Y.M.8
  • 136
    • 84896032568 scopus 로고    scopus 로고
    • HIF-1α and HIF-2α are critically involved in hypoxiainduced lipid accumulation in hepatocytes through reducing PGC-1α-mediated fatty acid β-oxidation
    • PMID: 24503013
    • Liu Y, Ma Z, Zhao C, Wang Y, Wu G, Xiao J, McClain CJ, Li X, Feng W. HIF-1α and HIF-2α are critically involved in hypoxiainduced lipid accumulation in hepatocytes through reducing PGC-1α-mediated fatty acid β-oxidation. Toxicol Lett 2014; 226: 117-123 [PMID: 24503013 DOI: 10.1016/j.toxlet.2014.01.033]
    • (2014) Toxicol Lett , vol.226 , pp. 117-123
    • Liu, Y.1    Ma, Z.2    Zhao, C.3    Wang, Y.4    Wu, G.5    Xiao, J.6    McClain, C.J.7    Li, X.8    Feng, W.9
  • 137
    • 77952536851 scopus 로고    scopus 로고
    • Incisor degeneration in rats induced by vascular endothelial growth factor/ fibroblast growth factor receptor tyrosine kinase inhibition
    • PMID: 20100840
    • Fletcher AM, Bregman CL, Woicke J, Salcedo TW, Zidell RH, Janke HE, Fang H, Janusz WJ, Schulze GE, Mense MG. Incisor degeneration in rats induced by vascular endothelial growth factor/ fibroblast growth factor receptor tyrosine kinase inhibition. Toxicol Pathol 2010; 38: 267-279 [PMID: 20100840 DOI: 10.1177/0192623309357950]
    • (2010) Toxicol Pathol , vol.38 , pp. 267-279
    • Fletcher, A.M.1    Bregman, C.L.2    Woicke, J.3    Salcedo, T.W.4    Zidell, R.H.5    Janke, H.E.6    Fang, H.7    Janusz, W.J.8    Schulze, G.E.9    Mense, M.G.10
  • 140
    • 84875592099 scopus 로고    scopus 로고
    • Cross talk between toll-like receptor-4 signaling and angiotensin-II in liver fibrosis development in the rat model of non-alcoholic steatohepatitis
    • PMID: 23301938
    • Shirai Y, Yoshiji H, Noguchi R, Kaji K, Aihara Y, Douhara A, Moriya K, Namisaki T, Kawaratani H, Fukui H. Cross talk between toll-like receptor-4 signaling and angiotensin-II in liver fibrosis development in the rat model of non-alcoholic steatohepatitis. J Gastroenterol Hepatol 2013; 28: 723-730 [PMID: 23301938 DOI:10.1111/jgh.12112]
    • (2013) J Gastroenterol Hepatol , vol.28 , pp. 723-730
    • Shirai, Y.1    Yoshiji, H.2    Noguchi, R.3    Kaji, K.4    Aihara, Y.5    Douhara, A.6    Moriya, K.7    Namisaki, T.8    Kawaratani, H.9    Fukui, H.10
  • 142
  • 144
    • 84886826434 scopus 로고    scopus 로고
    • Direct renin inhibitor, aliskiren, attenuates the progression of non-alcoholic steatohepatitis in the rat model
    • PMID: 23448275
    • Aihara Y, Yoshiji H, Noguchi R, Kaji K, Namisaki T, Shirai Y, Douhara A, Moriya K, Kawaratani H, Fukui H. Direct renin inhibitor, aliskiren, attenuates the progression of non-alcoholic steatohepatitis in the rat model. Hepatol Res 2013; 43: 1241-1250 [PMID: 23448275 DOI: 10.1111/hepr.12081]
    • (2013) Hepatol Res , vol.43 , pp. 1241-1250
    • Aihara, Y.1    Yoshiji, H.2    Noguchi, R.3    Kaji, K.4    Namisaki, T.5    Shirai, Y.6    Douhara, A.7    Moriya, K.8    Kawaratani, H.9    Fukui, H.10
  • 145
    • 0035991447 scopus 로고    scopus 로고
    • Inhibition of reninangiotensin system attenuates liver enzyme-altered preneoplastic lesions and fibrosis development in rats
    • PMID: 12076858
    • Yoshiji H, Yoshii J, Ikenaka Y, Noguchi R, Tsujinoue H, Nakatani T, Imazu H, Yanase K, Kuriyama S, Fukui H. Inhibition of reninangiotensin system attenuates liver enzyme-altered preneoplastic lesions and fibrosis development in rats. J Hepatol 2002; 37: 22-30 [PMID: 12076858 DOI: 10.1016/S0168-8278(02)00104-6]
    • (2002) J Hepatol , vol.37 , pp. 22-30
    • Yoshiji, H.1    Yoshii, J.2    Ikenaka, Y.3    Noguchi, R.4    Tsujinoue, H.5    Nakatani, T.6    Imazu, H.7    Yanase, K.8    Kuriyama, S.9    Fukui, H.10
  • 146
    • 84860865386 scopus 로고    scopus 로고
    • Effects of long term ethanol consumption mediated oxidative stress on neovessel generation in liver
    • PMID: 22394347
    • Das SK, Mukherjee S, Vasudevan DM. Effects of long term ethanol consumption mediated oxidative stress on neovessel generation in liver. Toxicol Mech Methods 2012; 22: 375-382 [PMID: 22394347 DOI: 10.3109/15376516.2012.666651]
    • (2012) Toxicol Mech Methods , vol.22 , pp. 375-382
    • Das, S.K.1    Mukherjee, S.2    Vasudevan, D.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.