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Volumn 38, Issue 5, 2003, Pages 660-667

Hepatocyte growth factor activates endothelial proangiogenic mechanisms relevant in chronic hepatitis C-associated neoangiogenesis

Author keywords

Cell proliferation; Chronic hepatitis C associated angiogenesis; Endothelial cell; Hepatocyte growth factor; Intercellular adhesion molecule; Vascular endothelial growth factor

Indexed keywords

BETA CATENIN; BETA3 INTEGRIN; CADHERIN; CELL ADHESION MOLECULE; RECEPTOR ANTIBODY; SCATTER FACTOR; THYMIDINE; TRITIUM; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR ANTIBODY;

EID: 0038555371     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(03)00053-9     Document Type: Article
Times cited : (50)

References (56)
  • 1
  • 2
    • 0031778206 scopus 로고    scopus 로고
    • Clinical significance of microvessel density and vascular endothelial growth factor expression in hepatocellular carcinoma and surrounding liver: Possible involvement of vascular endothelial growth factor in the angiogenesis of cirrhotic liver
    • El-Assal ON, Yamanoi A, Soda Y, Yamaguchi M, Igarashi M, Yamamoto A, et al. Clinical significance of microvessel density and vascular endothelial growth factor expression in hepatocellular carcinoma and surrounding liver: possible involvement of vascular endothelial growth factor in the angiogenesis of cirrhotic liver. Hepatology 1998;27:1554-1562.
    • (1998) Hepatology , vol.27 , pp. 1554-1562
    • El-Assal, O.N.1    Yamanoi, A.2    Soda, Y.3    Yamaguchi, M.4    Igarashi, M.5    Yamamoto, A.6
  • 4
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000;407:249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 6
    • 0025738047 scopus 로고
    • Hepatocyte growth factor-scatter factor: Mitogen, motogen and met
    • Gherardi E, Stroker M. Hepatocyte growth factor-scatter factor: mitogen, motogen and met. Cancer Cells 1991;3:227-232.
    • (1991) Cancer Cells , vol.3 , pp. 227-232
    • Gherardi, E.1    Stroker, M.2
  • 7
    • 0033065805 scopus 로고    scopus 로고
    • Expression of hepatocyte growth factor (HGF) and HGF receptor (c-met) proteins in liver diseases: An immunohistochemical study
    • Okano JI, Shiota G, Kawasaki H. Expression of hepatocyte growth factor (HGF) and HGF receptor (c-met) proteins in liver diseases: an immunohistochemical study. Liver 1999;19:151-159.
    • (1999) Liver , vol.19 , pp. 151-159
    • Okano, J.I.1    Shiota, G.2    Kawasaki, H.3
  • 8
    • 0031012852 scopus 로고    scopus 로고
    • Induction of hepatocyte growth factor activator messenger RNA in the liver following tissue injury and acute inflammation
    • Okajima A, Miyazawa K, Naitoh Y, Inoue K, Kitamura N. Induction of hepatocyte growth factor activator messenger RNA in the liver following tissue injury and acute inflammation. Hepatology 1997;25:97-102.
    • (1997) Hepatology , vol.25 , pp. 97-102
    • Okajima, A.1    Miyazawa, K.2    Naitoh, Y.3    Inoue, K.4    Kitamura, N.5
  • 9
    • 0026722243 scopus 로고
    • Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell mobility and growth
    • Bussolino F, DiRenzo MF, Ziche M, Bocchietto E, Olivero M, Naldini L, et al. Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell mobility and growth. J Cell Biol 1992;119:629-641.
    • (1992) J Cell Biol , vol.119 , pp. 629-641
    • Bussolino, F.1    DiRenzo, M.F.2    Ziche, M.3    Bocchietto, E.4    Olivero, M.5    Naldini, L.6
  • 11
    • 0032477844 scopus 로고    scopus 로고
    • Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor
    • Van Belle E, Witzenbichler B, Chen D, Silver M, Chang L, Schwall R, et al. Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor. Circulation 1998;97:381-390.
    • (1998) Circulation , vol.97 , pp. 381-390
    • Van Belle, E.1    Witzenbichler, B.2    Chen, D.3    Silver, M.4    Chang, L.5    Schwall, R.6
  • 13
    • 0029085510 scopus 로고
    • Functional properties of human vascular endothelial cadherin (7B4/Cadherin-5), an endothelial-specific cadherin
    • Breviario F, Caveda L, Corada M, Martin-Padura I, Navarro P, Golay J, et al. Functional properties of human vascular endothelial cadherin (7B4/Cadherin-5), an endothelial-specific cadherin. Arterioscler Thromb Vasc Biol 1995;15:1229-1239.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 1229-1239
    • Breviario, F.1    Caveda, L.2    Corada, M.3    Martin-Padura, I.4    Navarro, P.5    Golay, J.6
  • 14
    • 0029816130 scopus 로고    scopus 로고
    • Inhibition of cultured cell growth by vascular endothelial cadherin (cadherin-5/VE-cadherin)
    • Caveda L, Martin-Padura I, Navarro P, Breviario F, Corada M, Gulino D, et al. Inhibition of cultured cell growth by vascular endothelial cadherin (cadherin-5/VE-cadherin). J Clin Invest 1996;98:886-893.
    • (1996) J Clin Invest , vol.98 , pp. 886-893
    • Caveda, L.1    Martin-Padura, I.2    Navarro, P.3    Breviario, F.4    Corada, M.5    Gulino, D.6
  • 15
    • 0031040539 scopus 로고    scopus 로고
    • Chemokines: Leucocyte recruitment and activation cytokines
    • Adams DH, Lloyd AR. Chemokines: leucocyte recruitment and activation cytokines. Lancet 1997;349:490-495.
    • (1997) Lancet , vol.349 , pp. 490-495
    • Adams, D.H.1    Lloyd, A.R.2
  • 16
  • 18
    • 0033121275 scopus 로고    scopus 로고
    • The role of αv integrins during angiogenesis: Insights into potential mechanisms of action and clinical development
    • Eliceiri BP, Cheresh DA. The role of αv integrins during angiogenesis: insights into potential mechanisms of action and clinical development. J Clin Invest 1999;103:1227-1230.
    • (1999) J Clin Invest , vol.103 , pp. 1227-1230
    • Eliceiri, B.P.1    Cheresh, D.A.2
  • 19
    • 0029965462 scopus 로고    scopus 로고
    • Transient functional expression of αvβ3 on vascular cells during wound repair
    • Clark RAF, Tonnesen MG, Gailit J, Cheresh DA. Transient functional expression of αvβ3 on vascular cells during wound repair. Am J Pathol 1996;148:1407-1421.
    • (1996) Am J Pathol , vol.148 , pp. 1407-1421
    • Clark, R.A.F.1    Tonnesen, M.G.2    Gailit, J.3    Cheresh, D.A.4
  • 20
    • 15844420283 scopus 로고    scopus 로고
    • Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3
    • Brooks PC, Stromblad S, Sanders LC, von Schalscha TL, Aimes RT, Stetler-Stevenson WG, et al. Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3. Cell 1996;85:683-693.
    • (1996) Cell , vol.85 , pp. 683-693
    • Brooks, P.C.1    Stromblad, S.2    Sanders, L.C.3    Von Schalscha, T.L.4    Aimes, R.T.5    Stetler-Stevenson, W.G.6
  • 21
    • 0027008419 scopus 로고
    • Basic FGF and TGF-β differentially modulate integrin expression of human microvascular endothelial cells
    • Enenstein J, Waleh NS, Kramer RH. Basic FGF and TGF-β differentially modulate integrin expression of human microvascular endothelial cells. Exp Cell Res 1992;203:499-503.
    • (1992) Exp Cell Res , vol.203 , pp. 499-503
    • Enenstein, J.1    Waleh, N.S.2    Kramer, R.H.3
  • 22
    • 0026395163 scopus 로고
    • The vascular endothelial growth family: Identification of a fourth molecular species and characterization of alternative splicing of RNA
    • Houck KA, Ferrara N, Winer J, Cachianes G, Li B, Leung DW. The vascular endothelial growth family: identification of a fourth molecular species and characterization of alternative splicing of RNA. Mol Endocrinol 1991;5:1806-1814.
    • (1991) Mol Endocrinol , vol.5 , pp. 1806-1814
    • Houck, K.A.1    Ferrara, N.2    Winer, J.3    Cachianes, G.4    Li, B.5    Leung, D.W.6
  • 23
    • 0027249239 scopus 로고
    • Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelial cells
    • Quinn TP, Peters KG, De Vries C, Ferrara N, Williams LT. Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelial cells. Proc Natl Acad Sci USA 1993;90:7533-7537.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7533-7537
    • Quinn, T.P.1    Peters, K.G.2    De Vries, C.3    Ferrara, N.4    Williams, L.T.5
  • 24
  • 25
    • 0034220181 scopus 로고    scopus 로고
    • The growth inhibition of hepatoma by gene transfer of antisense vascular endothelial growth factor
    • Kang MA, Kim KY, Seol JY, Kim KC, Nam MJ. The growth inhibition of hepatoma by gene transfer of antisense vascular endothelial growth factor. J Gene Med 2000;2:289-296.
    • (2000) J Gene Med , vol.2 , pp. 289-296
    • Kang, M.A.1    Kim, K.Y.2    Seol, J.Y.3    Kim, K.C.4    Nam, M.J.5
  • 26
    • 2642607848 scopus 로고    scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor-mediated permeability occurs through disorganization of endothelial junctional proteins
    • Kevil CG, Payne DK, Mire E, Alexander JS. Vascular permeability factor/vascular endothelial growth factor-mediated permeability occurs through disorganization of endothelial junctional proteins. J Biol Chem. 1998;273:15099-15103.
    • (1998) J Biol Chem , vol.273 , pp. 15099-15103
    • Kevil, C.G.1    Payne, D.K.2    Mire, E.3    Alexander, J.S.4
  • 27
    • 0017785902 scopus 로고
    • Acute and chronic hepatitis revisited
    • International Group. Acute and chronic hepatitis revisited. Lancet 1977;2:914-919.
    • (1977) Lancet , vol.2 , pp. 914-919
  • 29
    • 0032482216 scopus 로고    scopus 로고
    • Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TAPA-1 and CD151/PETA-3 with alpha3 beta1 integrin localized at endothelial lateral junctions
    • Yáñez-Mo M, Alfranca A, Cabanas C, Marazuela M, Tejedor R, Ursa MA, et al. Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TAPA-1 and CD151/PETA-3 with alpha3 beta1 integrin localized at endothelial lateral junctions. J Cell Biol 1998;141:791-804.
    • (1998) J Cell Biol , vol.141 , pp. 791-804
    • Yáñez-Mo, M.1    Alfranca, A.2    Cabanas, C.3    Marazuela, M.4    Tejedor, R.5    Ursa, M.A.6
  • 30
    • 15844420283 scopus 로고    scopus 로고
    • Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3
    • Brooks PC, Stromblad S, Sanders LC, von Schalscha TL, Aimes RT, Stetler-Stevenson WG, et al. Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. Cell 1996;85:683-693.
    • (1996) Cell , vol.85 , pp. 683-693
    • Brooks, P.C.1    Stromblad, S.2    Sanders, L.C.3    Von Schalscha, T.L.4    Aimes, R.T.5    Stetler-Stevenson, W.G.6
  • 31
    • 0027225675 scopus 로고
    • Down-regulation of intercellular adhesion molecule 1 on hepatocytes in viral chronic hepatitis treated with interferon alpha-2b
    • García-Monzón C, García-Buey L, García-Sánchez A, Pajares JM, Moreno-Otero R. Down-regulation of intercellular adhesion molecule 1 on hepatocytes in viral chronic hepatitis treated with interferon alpha-2b. Gastroenterology 1993;105:462-469.
    • (1993) Gastroenterology , vol.105 , pp. 462-469
    • García-Monzón, C.1    García-Buey, L.2    García-Sánchez, A.3    Pajares, J.M.4    Moreno-Otero, R.5
  • 32
    • 0034745356 scopus 로고    scopus 로고
    • Rac recruits high-affinity integrin αvβ3 to lamellipodia in endothelial cell migration
    • Kiosses WB, Shattil SJ, Pampori N, Schwartz MA. Rac recruits high-affinity integrin αvβ3 to lamellipodia in endothelial cell migration. Nat Cell Biol 2001;3:316-320.
    • (2001) Nat Cell Biol , vol.3 , pp. 316-320
    • Kiosses, W.B.1    Shattil, S.J.2    Pampori, N.3    Schwartz, M.A.4
  • 33
    • 0032857478 scopus 로고    scopus 로고
    • Hepatocellular hypoxia-induced vascular endothelial growth factor expression and angiogenesis in experimental biliary cirrhosis
    • Rosmorduc O, Wendum D, Corpechot C, Galy B, Sebbagh N, Raleigh J, et al. Hepatocellular hypoxia-induced vascular endothelial growth factor expression and angiogenesis in experimental biliary cirrhosis. Am J Pathol 1999;155:1065-1073.
    • (1999) Am J Pathol , vol.155 , pp. 1065-1073
    • Rosmorduc, O.1    Wendum, D.2    Corpechot, C.3    Galy, B.4    Sebbagh, N.5    Raleigh, J.6
  • 34
    • 0033071015 scopus 로고    scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor mRNA expression in patients with chronic hepatitis C and hepatocellular carcinoma
    • Shimoda K, Mori M, Shibuta K, Banner BF, Barnard GF. Vascular endothelial growth factor/vascular permeability factor mRNA expression in patients with chronic hepatitis C and hepatocellular carcinoma. Int J Oncol 1999;14:353-359.
    • (1999) Int J Oncol , vol.14 , pp. 353-359
    • Shimoda, K.1    Mori, M.2    Shibuta, K.3    Banner, B.F.4    Barnard, G.F.5
  • 35
    • 12644304863 scopus 로고    scopus 로고
    • CVH induced by hepatitis C but not hepatitis B virus infection correlates with increased liver angiogenesis
    • Mazzanti R, Messerini L, Monsacchi L, Buzzelli G, Zignego AL, Foschi M, et al. CVH induced by hepatitis C but not hepatitis B virus infection correlates with increased liver angiogenesis. Hepatology 1997;25:229-234.
    • (1997) Hepatology , vol.25 , pp. 229-234
    • Mazzanti, R.1    Messerini, L.2    Monsacchi, L.3    Buzzelli, G.4    Zignego, A.L.5    Foschi, M.6
  • 36
    • 0025820031 scopus 로고
    • Morphological changes of hepatic microcirculation in experimental rat cirrhosis: A scanning electron microscopic study
    • Haratake J, Hisaoka M, Yamamoto O, Horie A. Morphological changes of hepatic microcirculation in experimental rat cirrhosis: a scanning electron microscopic study. Hepatology 1991;13:952-956.
    • (1991) Hepatology , vol.13 , pp. 952-956
    • Haratake, J.1    Hisaoka, M.2    Yamamoto, O.3    Horie, A.4
  • 37
    • 0032504607 scopus 로고    scopus 로고
    • Up-regulation of vascular endothelial growth factor induced by hepatocyte growth factor/scatter factor stimulation in human glioma cells
    • Moriyama T, Kataoka H, Hamasuna R, Yokogami K, Uehara H, Kawano H, et al. Up-regulation of vascular endothelial growth factor induced by hepatocyte growth factor/scatter factor stimulation in human glioma cells. Biochem Biophys Res Commun 1998;249:73-77.
    • (1998) Biochem Biophys Res Commun , vol.249 , pp. 73-77
    • Moriyama, T.1    Kataoka, H.2    Hamasuna, R.3    Yokogami, K.4    Uehara, H.5    Kawano, H.6
  • 38
    • 0032900187 scopus 로고    scopus 로고
    • Hepatocyte growth factor increases expression of vascular endothelial growth factor and plasminogen activator inhibitor-1 in human keratinocytes and the vascular endothelial growth factor receptor flk-1 in human endothelial cells
    • Wojta J, Kaun C, Breuss JM, Koshelnick Y, Beckmann R, Hattey E, et al. Hepatocyte growth factor increases expression of vascular endothelial growth factor and plasminogen activator inhibitor-1 in human keratinocytes and the vascular endothelial growth factor receptor flk-1 in human endothelial cells. Lab Invest 1999;79:427-438.
    • (1999) Lab Invest , vol.79 , pp. 427-438
    • Wojta, J.1    Kaun, C.2    Breuss, J.M.3    Koshelnick, Y.4    Beckmann, R.5    Hattey, E.6
  • 39
    • 0009993110 scopus 로고    scopus 로고
    • Disruption of cadherin-related junctions triggers autocrine expression of vascular endothelial growth factor in bovine aortic endothelial cells: Effects on cell proliferation and death resistance
    • Castilla MA, Arroyo MV, Aceituno E, Aragoncillo P, Gonzalez-Pacheco FR, Texeiro E, et al. Disruption of cadherin-related junctions triggers autocrine expression of vascular endothelial growth factor in bovine aortic endothelial cells: effects on cell proliferation and death resistance. Circ Res 1999;85:1132-1138.
    • (1999) Circ Res , vol.85 , pp. 1132-1138
    • Castilla, M.A.1    Arroyo, M.V.2    Aceituno, E.3    Aragoncillo, P.4    Gonzalez-Pacheco, F.R.5    Texeiro, E.6
  • 40
    • 0035102323 scopus 로고    scopus 로고
    • Hepatocyte growth factor enhances vascular endothelial growth factor-induced angiogenesis in vitro and in vivo
    • Xin X, Yang S, Ingle G, Zlot C, Rangell L, Kowalski J, et al. Hepatocyte growth factor enhances vascular endothelial growth factor-induced angiogenesis in vitro and in vivo. Am J Pathol 2001;158:1111-1120.
    • (2001) Am J Pathol , vol.158 , pp. 1111-1120
    • Xin, X.1    Yang, S.2    Ingle, G.3    Zlot, C.4    Rangell, L.5    Kowalski, J.6
  • 41
    • 0032440723 scopus 로고    scopus 로고
    • Distinct signal transduction pathways are utilized during the tube formation and survival phases of in vitro angiogenesis
    • Ilan N, Mahooti S, Madri JA. Distinct signal transduction pathways are utilized during the tube formation and survival phases of in vitro angiogenesis. J Cell Sci 1998;111:3621-3631.
    • (1998) J Cell Sci , vol.111 , pp. 3621-3631
    • Ilan, N.1    Mahooti, S.2    Madri, J.A.3
  • 42
    • 0034905295 scopus 로고    scopus 로고
    • Hepatocyte growth factor modulates vascular endothelial-cadherin expression in human endothelial cells
    • Martin TA, Mansel R, Jiang WG. Hepatocyte growth factor modulates vascular endothelial-cadherin expression in human endothelial cells. Clin Cancer Res 2001;7:734-737.
    • (2001) Clin Cancer Res , vol.7 , pp. 734-737
    • Martin, T.A.1    Mansel, R.2    Jiang, W.G.3
  • 43
    • 0030926845 scopus 로고    scopus 로고
    • Characterization of the interactions of α-catenin with alpha-actinin and β-catenin/plakoglobin
    • Nieset JE, Redfield AR, Jin F, Knudsen KA, Johnson KR, Wheelock MJ. Characterization of the interactions of α-catenin with alpha-actinin and β-catenin/plakoglobin. J Cell Sci 1997;110:1013-1022.
    • (1997) J Cell Sci , vol.110 , pp. 1013-1022
    • Nieset, J.E.1    Redfield, A.R.2    Jin, F.3    Knudsen, K.A.4    Johnson, K.R.5    Wheelock, M.J.6
  • 44
    • 0033597718 scopus 로고    scopus 로고
    • Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis
    • Carmeliet P, Lampugnani MG, Moons L, Breviario F, Compernolle V, Bono F, et al. Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis. Cell 1999;98:147-157.
    • (1999) Cell , vol.98 , pp. 147-157
    • Carmeliet, P.1    Lampugnani, M.G.2    Moons, L.3    Breviario, F.4    Compernolle, V.5    Bono, F.6
  • 45
    • 0036315009 scopus 로고    scopus 로고
    • Hepatocyte growth factor enhances endothelial cell barrier function and cortical cytoskeletal rearrangement: Potential role of glycogen synthase kinase-3beta
    • Liu F, Schaphorst KL, Verin AD, Jacobs K, Birukova A, Day RM, et al. Hepatocyte growth factor enhances endothelial cell barrier function and cortical cytoskeletal rearrangement: potential role of glycogen synthase kinase-3beta. FASEB J 2002;16:950-962.
    • (2002) FASEB J , vol.16 , pp. 950-962
    • Liu, F.1    Schaphorst, K.L.2    Verin, A.D.3    Jacobs, K.4    Birukova, A.5    Day, R.M.6
  • 46
    • 0032862259 scopus 로고    scopus 로고
    • Hepatocyte growth factor/scatter factor decreases the expression of occludin and transendothelial resistance (TER) and increases paracellular permeability in human vascular endothelial cells
    • Jiang WG, Martin TA, Matsumoto K, Nakamura T, Mansel RE. Hepatocyte growth factor/scatter factor decreases the expression of occludin and transendothelial resistance (TER) and increases paracellular permeability in human vascular endothelial cells. J Cell Physiol 1999;181:319-329.
    • (1999) J Cell Physiol , vol.181 , pp. 319-329
    • Jiang, W.G.1    Martin, T.A.2    Matsumoto, K.3    Nakamura, T.4    Mansel, R.E.5
  • 47
    • 0028670833 scopus 로고
    • Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • Brooks PC, Montgomery AM, Rosenfeld M, Reisfeld RA, Hu T, Klier G, et al. Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 1994;79:1157-1164.
    • (1994) Cell , vol.79 , pp. 1157-1164
    • Brooks, P.C.1    Montgomery, A.M.2    Rosenfeld, M.3    Reisfeld, R.A.4    Hu, T.5    Klier, G.6
  • 48
    • 0028362876 scopus 로고
    • Requirement of vascular integrin αvβ3 for angiogenesis
    • Brooks PC, Clark RA, Cheresh DA. Requirement of vascular integrin αvβ3 for angiogenesis. Science 1994;264:569-571.
    • (1994) Science , vol.264 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 51
    • 0029925079 scopus 로고    scopus 로고
    • Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization
    • Hammes HP, Brownlee M, Jonczyk A, Sutter A, Preissner KT. Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization. Nat Med 1996;2:529-533.
    • (1996) Nat Med , vol.2 , pp. 529-533
    • Hammes, H.P.1    Brownlee, M.2    Jonczyk, A.3    Sutter, A.4    Preissner, K.T.5
  • 52
    • 15844420283 scopus 로고    scopus 로고
    • Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3
    • Brooks PC, Stromblad S, Sanders LC, von Schalscha TL, Aimes RT, Stetler-Stevenson WG, et al. Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3. Cell 1996;85:683-693.
    • (1996) Cell , vol.85 , pp. 683-693
    • Brooks, P.C.1    Stromblad, S.2    Sanders, L.C.3    Von Schalscha, T.L.4    Aimes, R.T.5    Stetler-Stevenson, W.G.6
  • 53
    • 0035793037 scopus 로고    scopus 로고
    • Disruption of matrix metalloproteinase 2 binding to integrin αvβ3 by an organic molecule inhibits angiogenesis and tumor growth in vivo
    • Silletti S, Kessler T, Goldberg J, Boger DL, Cheresh DA. Disruption of matrix metalloproteinase 2 binding to integrin αvβ3 by an organic molecule inhibits angiogenesis and tumor growth in vivo. Proc Natl Acad Sci USA 2001;98:119-124.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 119-124
    • Silletti, S.1    Kessler, T.2    Goldberg, J.3    Boger, D.L.4    Cheresh, D.A.5
  • 54
    • 0032498640 scopus 로고    scopus 로고
    • Integrin αvβ3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis
    • Eliceiri BP, Klemke R, Stromblad S, Cheresh DA. Integrin αvβ3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis. J Cell Biol 1998;140:1255-1263.
    • (1998) J Cell Biol , vol.140 , pp. 1255-1263
    • Eliceiri, B.P.1    Klemke, R.2    Stromblad, S.3    Cheresh, D.A.4
  • 55
    • 0030814976 scopus 로고    scopus 로고
    • Alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF
    • Schneller M, Vuori K, Ruoslahti E. Alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF. EMBO J 1997;16:5600-5607.
    • (1997) EMBO J , vol.16 , pp. 5600-5607
    • Schneller, M.1    Vuori, K.2    Ruoslahti, E.3
  • 56
    • 0033558087 scopus 로고    scopus 로고
    • Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2
    • Soldi R, Mitola S, Strasly M, Defilippi P, Tarone G, Bussolino F. Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2. EMBO J 1999;18:882-892.
    • (1999) EMBO J , vol.18 , pp. 882-892
    • Soldi, R.1    Mitola, S.2    Strasly, M.3    Defilippi, P.4    Tarone, G.5    Bussolino, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.