메뉴 건너뛰기




Volumn 136, Issue 1, 2009, Pages

Liver Cell-Derived Microparticles Activate Hedgehog Signaling and Alter Gene Expression in Hepatic Endothelial Cells

Author keywords

[No Author keywords available]

Indexed keywords

MORPHOGEN; PLATELET DERIVED GROWTH FACTOR; SONIC HEDGEHOG PROTEIN; PLATELET DERIVED GROWTH FACTOR BB; PLATELET-DERIVED GROWTH FACTOR BB;

EID: 59849085125     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2008.09.066     Document Type: Article
Times cited : (193)

References (34)
  • 2
    • 34047175876 scopus 로고    scopus 로고
    • Vascular endothelial dysfunction in cirrhosis
    • Iwakiri Y., and Groszmann R.J. Vascular endothelial dysfunction in cirrhosis. J Hepatol 46 (2007) 927-934
    • (2007) J Hepatol , vol.46 , pp. 927-934
    • Iwakiri, Y.1    Groszmann, R.J.2
  • 3
    • 35948964347 scopus 로고    scopus 로고
    • Hepatic stellate cells and liver fibrosis
    • Moreira R.K. Hepatic stellate cells and liver fibrosis. Arch Pathol Lab Med 131 (2007) 1728-1734
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 1728-1734
    • Moreira, R.K.1
  • 4
    • 48549088729 scopus 로고    scopus 로고
    • PDGF signaling through ephrin-b2 regulates hepatic vascular structure and function
    • Semela D., Das A., Langer D., et al. PDGF signaling through ephrin-b2 regulates hepatic vascular structure and function. Gastroenterology 135 (2008) 671-679
    • (2008) Gastroenterology , vol.135 , pp. 671-679
    • Semela, D.1    Das, A.2    Langer, D.3
  • 5
    • 4644226671 scopus 로고    scopus 로고
    • Hedgehog signaling is essential for endothelial tube formation during vasculogenesis
    • Vokes S.A., Yatskievych T.A., Heimark R.L., et al. Hedgehog signaling is essential for endothelial tube formation during vasculogenesis. Development 131 (2004) 4371-4380
    • (2004) Development , vol.131 , pp. 4371-4380
    • Vokes, S.A.1    Yatskievych, T.A.2    Heimark, R.L.3
  • 6
    • 77649099284 scopus 로고    scopus 로고
    • Sonic hedgehog regulates angiogenesis and myogenesis during post-natal skeletal muscle regeneration
    • Straface G., Aprahamian T., Flex A., et al. Sonic hedgehog regulates angiogenesis and myogenesis during post-natal skeletal muscle regeneration. J Cell Mol Med (2008)
    • (2008) J Cell Mol Med
    • Straface, G.1    Aprahamian, T.2    Flex, A.3
  • 7
    • 33744466786 scopus 로고    scopus 로고
    • Topical sonic hedgehog gene therapy accelerates wound healing in diabetes by enhancing endothelial progenitor cell-mediated microvascular remodeling
    • Asai J., Takenaka H., Kusano K.F., et al. Topical sonic hedgehog gene therapy accelerates wound healing in diabetes by enhancing endothelial progenitor cell-mediated microvascular remodeling. Circulation 113 (2006) 2413-2424
    • (2006) Circulation , vol.113 , pp. 2413-2424
    • Asai, J.1    Takenaka, H.2    Kusano, K.F.3
  • 8
    • 50249151525 scopus 로고    scopus 로고
    • The hedgehog pathway regulates remodeling responses to biliary obstruction in rats
    • Omenetti A., Popov Y., Jung Y., et al. The hedgehog pathway regulates remodeling responses to biliary obstruction in rats. Gut 57 (2008) 1275-1282
    • (2008) Gut , vol.57 , pp. 1275-1282
    • Omenetti, A.1    Popov, Y.2    Jung, Y.3
  • 10
    • 33244463974 scopus 로고    scopus 로고
    • Hedgehog lipid modifications are required for Hedgehog stabilization in the extracellular matrix
    • Callejo A., Torroja C., Quijada L., et al. Hedgehog lipid modifications are required for Hedgehog stabilization in the extracellular matrix. Development 133 (2006) 471-483
    • (2006) Development , vol.133 , pp. 471-483
    • Callejo, A.1    Torroja, C.2    Quijada, L.3
  • 11
    • 34548474286 scopus 로고    scopus 로고
    • Shh carried by microparticles corrects endothelial injury through nitric oxide release
    • Agouni A., Mostefai H.A., Porro C., et al. Shh carried by microparticles corrects endothelial injury through nitric oxide release. FASEB J 21 (2007) 2735-2741
    • (2007) FASEB J , vol.21 , pp. 2735-2741
    • Agouni, A.1    Mostefai, H.A.2    Porro, C.3
  • 12
    • 33745280126 scopus 로고    scopus 로고
    • The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in C. elegans
    • Liegeois S., Benedetto A., Garnier J.M., et al. The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in C. elegans. Cell Biol 173 (2006) 949-961
    • (2006) Cell Biol , vol.173 , pp. 949-961
    • Liegeois, S.1    Benedetto, A.2    Garnier, J.M.3
  • 13
    • 34247369797 scopus 로고    scopus 로고
    • Hedgehog-mediated mesenchymal-epithelial interactions modulate hepatic response to bile duct ligation
    • Omenetti A., Yang L., Li Y.X., et al. Hedgehog-mediated mesenchymal-epithelial interactions modulate hepatic response to bile duct ligation. Lab Invest 87 (2007) 499-514
    • (2007) Lab Invest , vol.87 , pp. 499-514
    • Omenetti, A.1    Yang, L.2    Li, Y.X.3
  • 14
    • 19944434048 scopus 로고    scopus 로고
    • Measuring circulating cell-derived microparticles
    • Jy W., Horstman L.L., Jimenez J.J., et al. Measuring circulating cell-derived microparticles. J Thromb Haemost 2 (2004) 1842-1851
    • (2004) J Thromb Haemost , vol.2 , pp. 1842-1851
    • Jy, W.1    Horstman, L.L.2    Jimenez, J.J.3
  • 15
    • 34047111681 scopus 로고    scopus 로고
    • Circulating microparticles: pathophysiology and clinical implications
    • Piccin A., and Murphy W.G. Circulating microparticles: pathophysiology and clinical implications. Blood Rev 21 (2007) 157-171
    • (2007) Blood Rev , vol.21 , pp. 157-171
    • Piccin, A.1    Murphy, W.G.2
  • 16
    • 0035877018 scopus 로고    scopus 로고
    • Proteomic analysis of dendritic cell-derived exosomes
    • Thery C., Boussac M., Veron P., et al. Proteomic analysis of dendritic cell-derived exosomes. J Immunol 166 (2001) 7309-7318
    • (2001) J Immunol , vol.166 , pp. 7309-7318
    • Thery, C.1    Boussac, M.2    Veron, P.3
  • 17
    • 0033767690 scopus 로고    scopus 로고
    • Exosome: from internal vesicle of the multivesicular body to intercellular signaling device
    • Denzer K., Kleijmeer M.J., Heijnen H.F., et al. Exosome: from internal vesicle of the multivesicular body to intercellular signaling device. J Cell Sci 113 (2000) 3365-3374
    • (2000) J Cell Sci , vol.113 , pp. 3365-3374
    • Denzer, K.1    Kleijmeer, M.J.2    Heijnen, H.F.3
  • 18
    • 0030796417 scopus 로고    scopus 로고
    • Silymarin retards collagen accumulation in early and advanced biliary fibrosis secondary to complete bile duct obliteration in rats
    • Boigk G., Stroedter L., Herbst H., et al. Silymarin retards collagen accumulation in early and advanced biliary fibrosis secondary to complete bile duct obliteration in rats. Hepatology 26 (1997) 643-649
    • (1997) Hepatology , vol.26 , pp. 643-649
    • Boigk, G.1    Stroedter, L.2    Herbst, H.3
  • 19
    • 0347379916 scopus 로고    scopus 로고
    • Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein jinase B/Akt
    • Liu S., Premont R.T., Kontos C.D., et al. Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein jinase B/Akt. J Biol Chem 278 (2003) 49929-49935
    • (2003) J Biol Chem , vol.278 , pp. 49929-49935
    • Liu, S.1    Premont, R.T.2    Kontos, C.D.3
  • 20
    • 0026341256 scopus 로고
    • Characterization of fat-storing cell lines derived from normal and CCl4-cirrhotic livers
    • Greenwel P., Schwartz M., Rosas M., et al. Characterization of fat-storing cell lines derived from normal and CCl4-cirrhotic livers. Lab Invest 65 (1991) 644-653
    • (1991) Lab Invest , vol.65 , pp. 644-653
    • Greenwel, P.1    Schwartz, M.2    Rosas, M.3
  • 21
    • 0032442997 scopus 로고    scopus 로고
    • Primary culture of cholangiocytes from normal mouse liver
    • Yahagi K., Ishii M., Kobayashi K., et al. Primary culture of cholangiocytes from normal mouse liver. In Vitro Cell Dev Biol Anim 34 (1998) 512-514
    • (1998) In Vitro Cell Dev Biol Anim , vol.34 , pp. 512-514
    • Yahagi, K.1    Ishii, M.2    Kobayashi, K.3
  • 22
    • 0029989258 scopus 로고    scopus 로고
    • B lymphocytes secrete antigen-presenting vesicles
    • Raposo G., Nijman H.W., Stoorvogel W., et al. B lymphocytes secrete antigen-presenting vesicles. J Exp Med 183 (1996) 1161-1172
    • (1996) J Exp Med , vol.183 , pp. 1161-1172
    • Raposo, G.1    Nijman, H.W.2    Stoorvogel, W.3
  • 23
    • 34247619364 scopus 로고    scopus 로고
    • Gene expression profiles during hepatic stellate cell activation in culture and in vivo
    • De Minicis S., Seki E., Uchinami H., et al. Gene expression profiles during hepatic stellate cell activation in culture and in vivo. Gastroenterology 132 (2007) 1937-1946
    • (2007) Gastroenterology , vol.132 , pp. 1937-1946
    • De Minicis, S.1    Seki, E.2    Uchinami, H.3
  • 24
    • 36549011761 scopus 로고    scopus 로고
    • Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells
    • Yang L., Wang Y., Mao H., et al. Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells. J Hepatol 48 (2008) 98-106
    • (2008) J Hepatol , vol.48 , pp. 98-106
    • Yang, L.1    Wang, Y.2    Mao, H.3
  • 25
    • 4644371414 scopus 로고    scopus 로고
    • Rat liver sinusoidal endothelial cell phenotype is maintained by paracrine and autocrine regulation
    • DeLeve L.D., Wang X., Hu L., et al. Rat liver sinusoidal endothelial cell phenotype is maintained by paracrine and autocrine regulation. Am J Physiol Gastrointest Liver Physiol 287 (2004) G757-G763
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287
    • DeLeve, L.D.1    Wang, X.2    Hu, L.3
  • 26
    • 0030822858 scopus 로고    scopus 로고
    • Regulation of inducible nitric oxide synthase and nitric oxide during hepatic injury and fibrogenesis
    • Rockey D.C., and Chung J.J. Regulation of inducible nitric oxide synthase and nitric oxide during hepatic injury and fibrogenesis. Am J Physiol 273 (1997) G124-G130
    • (1997) Am J Physiol , vol.273
    • Rockey, D.C.1    Chung, J.J.2
  • 27
    • 2942742564 scopus 로고    scopus 로고
    • Novel lipid modifications of secreted protein signals
    • Mann R.K., and Beachy P.A. Novel lipid modifications of secreted protein signals. Annu Rev Biochem 73 (2004) 891-923
    • (2004) Annu Rev Biochem , vol.73 , pp. 891-923
    • Mann, R.K.1    Beachy, P.A.2
  • 28
    • 38949218488 scopus 로고    scopus 로고
    • Patched, the receptor of Hedgehog, is a lipoprotein receptor
    • Callejo A., Culi J., and Guerrero I. Patched, the receptor of Hedgehog, is a lipoprotein receptor. Proc Natl Acad Sci U S A 105 (2008) 912-917
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 912-917
    • Callejo, A.1    Culi, J.2    Guerrero, I.3
  • 29
    • 0033802650 scopus 로고    scopus 로고
    • Pulmonary dysfunction in chronic liver disease
    • Fallon M.B., and Abrams G.A. Pulmonary dysfunction in chronic liver disease. Hepatology 32 (2000) 859-865
    • (2000) Hepatology , vol.32 , pp. 859-865
    • Fallon, M.B.1    Abrams, G.A.2
  • 30
    • 48949104124 scopus 로고    scopus 로고
    • Serum levels of soluble vascular cell adhesion molecule are related to hyperdynamic circulation in patients with liver cirrhosis
    • Lo Iacono O., Rincon D., Hernando A., et al. Serum levels of soluble vascular cell adhesion molecule are related to hyperdynamic circulation in patients with liver cirrhosis. Liver Int 28 (2008) 1129-1135
    • (2008) Liver Int , vol.28 , pp. 1129-1135
    • Lo Iacono, O.1    Rincon, D.2    Hernando, A.3
  • 31
    • 52949112610 scopus 로고    scopus 로고
    • Circulating vascular endothelial growth factor and its soluble receptors in patients with liver cirrhosis
    • Jaroszewicz J., Januszkiewicz M., Flisiak R., et al. Circulating vascular endothelial growth factor and its soluble receptors in patients with liver cirrhosis. Cytokine 44 (2008) 14-17
    • (2008) Cytokine , vol.44 , pp. 14-17
    • Jaroszewicz, J.1    Januszkiewicz, M.2    Flisiak, R.3
  • 32
    • 51349168307 scopus 로고    scopus 로고
    • SEC prevent rat stellate cell activation and promote reversion to quiescence
    • Deleve L.D., Wang X., Guo Y., et al. SEC prevent rat stellate cell activation and promote reversion to quiescence. Hepatology 48 (2008) 920-930
    • (2008) Hepatology , vol.48 , pp. 920-930
    • Deleve, L.D.1    Wang, X.2    Guo, Y.3
  • 33
    • 13144298531 scopus 로고    scopus 로고
    • Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors
    • Olsen C.L., Hsu P.P., Glienke J., et al. Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors. BMC Cancer 4 (2004) 43
    • (2004) BMC Cancer , vol.4 , pp. 43
    • Olsen, C.L.1    Hsu, P.P.2    Glienke, J.3
  • 34
    • 35848949969 scopus 로고    scopus 로고
    • Vascular deterioration in cirrhosis: the big picture
    • Bosch J. Vascular deterioration in cirrhosis: the big picture. J Clin Gastroenterol 41 (2007) S247-S253
    • (2007) J Clin Gastroenterol , vol.41
    • Bosch, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.