Hepatic angiogenesis and fibrosis are common features in morbidly obese patients

Hepatology International

Volumn 7, Issue 1, 2013, Pages 233-240

  Ciupińska Kajor, Monika ^a   Hartleb, Marek ^a   Kajor, MacIej ^a   Kukla, Michał ^a   Wyleżoł, Mariusz ^b   Lange, Dariusz ^c   Liszka, Łukasz ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

^b MILITARY INSTITUTE OF AVIATION MEDICINE   (Poland)

^c INSTITUTE OF ONCOLOGY   (Poland)

Author keywords

Angiogenesis; Fibrosis; Morbid obesity; NAFLD

Indexed keywords

CD34 ANTIGEN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR 2;

ADULT; ANGIOGENESIS; APOPTOSIS; ARTICLE; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE CLASSIFICATION; DISEASE SEVERITY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER BIOPSY; LIVER CELL; LIVER FIBROSIS; MALE; MORBID OBESITY; NICK END LABELING; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL;

EID: 84875273697     PISSN: 19360533     EISSN: 19360541     Source Type: Journal    
DOI: 10.1007/s12072-011-9320-9     Document Type: Article

References (31)

1. S Parekh FA Anania 2007 Abnormal lipid and glucose metabolism in obesity: implications for nonalcoholic fatty liver disease Gastroenterology 132 2191 2207 17498512 10.1053/j.gastro.2007.03.055 1:CAS:528:DC%2BD2sXmsVyns7g%3D
2. P Angulo 2007 Obesity and nonalcoholic fatty liver disease Nutr Rev 65 57 63 10.1301/nr.2007.jun.S57-S63
3. G Tarantino 2007 Should nonalcoholic fatty liver disease be regarded as a hepatic illness only? World J Gastroenterol 13 4669 4672 17729388 1:CAS:528:DC%2BD2sXhtFyjsbbO
4. C Boza A Riquelme L Ibañez, et al. 2005 Predictors of nonalcoholic steatohepatitis (NASH) in obese patients undergoing gastric bypass Obes Surg 15 1148 1153 16197788 10.1381/0960892055002347
5. JS Lee D Semela J Iredale VH Shah 2007 Sinusoidal remodeling and angiogenesis: a new function for the liver-specific pericyte? Hepatology 45 817 825 17326208 10.1002/hep.21564 1:CAS:528:DC%2BD2sXjs1Gku7c%3D
6. J Medina P Sanz-Cameno L Garcia-Buey S Martin-Vilchez M Lopez-Cabrera R Moreno-Otero 2005 Evidence of angiogenesis in primary biliary cirrhosis: an immunohistochemical descriptive study J Hepatol 42 124 131 15629517 10.1016/j.jhep.2004.09.024 1:CAS:528:DC%2BD2MXksVOg
7. S Aleffi I Petrai C Bertolani, et al. 2005 Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells Hepatology 42 1339 1348 16317688 10.1002/hep.20965 1:CAS:528: DC%2BD2MXhtlGns7rK
8. DE Kleiner EM Brunt M Van Natta, et al. 2005 Design and validation of a histological scoring system for nonalcoholic fatty liver disease Hepatology 41 1313 1321 15915461 10.1002/hep.20701
9. V Ratziu P Giral F Charlotte, et al. 2000 Liver fibrosis in overweight patients Gastroenterology 118 1117 1123 10833486 10.1016/S0016-5085(00)70364-7 1:STN:280:DC%2BD3c3psFSntg%3D%3D
10. IR Willner B Waters SR Patil A Reuben J Morelli CA Riely 2001 Ninety patients with nonalcoholic steatohepatitis: Insulin resistance, familial tendency, and severity of disease Am J Gastroenterol 96 2957 2961 11693332 10.1111/j.1572-0241.2001.04667.x 1:STN:280:DC%2BD3MnjvVWqsQ%3D%3D
11. P Angulo 2002 Nonalcoholic fatty liver disease N Engl J Med 346 1221 1231 11961152 10.1056/NEJMra011775 1:CAS:528:DC%2BD38XivVOmsrY%3D
12. GA Abrams SS Kunde AJ Lazenby RH Clements 2004 Portal fibrosis and hepatic steatosis in morbidly obese subjects: a spectrum of nonalcoholic fatty liver disease Hepatology 40 475 483 15368453 10.1002/hep.20323
13. JB Dixon PS Bhathal PE O'Brien 2001 Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese Gastroenterology 121 91 100 11438497 10.1053/gast.2001.25540 1:CAS:528:DC%2BD3MXlt1ykt70%3D
14. JP Ong H Elariny R Collantes, et al. 2005 Predictors of nonalcoholic steatohepatitis and advanced fibrosis in morbidly obese patients Obes Surg 15 310 315 15826462 10.1381/0960892053576820
15. PM Gholam L Flacbaum JT Machan DA Charney S Kotler 2007 Nonalcoholic fatty liver disease in severely obese subjects Am J Gastroenterol 102 399 408 17311652 10.1111/j.1572-0241.2006.01041.x 1:CAS:528:DC%2BD2sXivF2ksb0%3D
16. HL Huang WY Lin LT Lee HH Wang WJ Lee KC Huang 2007 Metabolic syndrome is related to nonalcoholic steatohepatitis in severely obese subjects Obes Surg 17 1457 1463 18219772 10.1007/s11695-008-9423-0
17. MI Minervini K Ruppert P Fontes, et al. 2009 Liver biopsy findings from healthy potential liver donors: reasons for disqualification, silent diseases and correlation with liver injury tests J Hepatol 50 501 510 19155086 10.1016/j.jhep.2008.10.030
18. JY Lee KM Kim SG Lee, et al. 2007 Prevalence and risk factors of non-alcoholic fatty liver disease in potential living liver donors in Korea: a review of 589 consecutive liver biopsies in a single center J Hepatol 47 239 244 17400323 10.1016/j.jhep.2007.02.007
19. G Marchesini E Bugianesi G Forlani, et al. 2003 Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome Hepatology 37 917 923 12668987 10.1053/jhep.2003.50161
20. CK Ryan LA Johnson BI Germin A Marcos 2002 One hundred consecutive hepatic biopsies in the workup of living donors for right lobe liver transplantation Liver Transpl 8 1114 1122 12474149 10.1053/jlts.2002.36740
21. F Angelico M Del Ben R Conti, et al. 2003 Non-alcoholic fatty liver syndrome: a hepatic consequence of common metabolic diseases J Gastroenterol Hepatol 18 588 594 12702052 10.1046/j.1440-1746.2003.02958.x
22. AE Feldstein A Canbay P Angulo, et al. 2003 Hepatocyte apoptosis and Fas expression are prominent features of human nonalcoholic steatohepatitis Gastroenterology 125 437 443 12891546 10.1016/S0016-5085(03)00907-7
23. PS Ribeiro H Cortez-Pinto S Solá, et al. 2004 Hepatocyte apoptosis, expression of death receptors, and activation of NF-kappaB in the liver of nonalcoholic and alcoholic steatohepatitis patients Am J Gastroenterol 99 1708 1717 15330907 10.1111/j.1572-0241.2004.40009.x 1:CAS:528: DC%2BD2cXos1egtbo%3D
24. P Mofrad MJ Contos M Haque, et al. 2003 Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT value Hepatology 37 1286 1292 12774006 10.1053/jhep.2003.50229
25. M Machado P Marques-Vidal H Corez-Pinto 2006 Hepatic histology in obese patients undergoing bariatric surgery J Hepatol 45 600 606 16899321 10.1016/j.jhep.2006.06.013
26. TC Schreuder BJ Verwer CM van Nieuwkerk CJ Mulder 2008 Nonalcoholic fatty liver disease: an overview of current insights in pathogenesis, diagnosis and treatment World J Gastroenterol 14 2474 2486 18442193 10.3748/wjg.14.2474 1:CAS:528:DC%2BD1cXptlWgs7s%3D
27. P Angulo JC Keach KP Batts KD Lindor 1999 Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis Hepatology 30 1356 1362 10573511 10.1002/hep.510300604 1:STN:280:DC%2BD3c%2Fkt1ejtQ%3D%3D
28. P Sorrentino G Tarantino P Conca, et al. 2004 Silent non-alcoholic fatty liver disease-a clinical-histological study J Hepatol 41 751 757 15519647 10.1016/j.jhep.2004.07.010 1:CAS:528:DC%2BD2cXptFKku7Y%3D
29. E Fassio E Alvarez N Dominguez G Landeira C Longo 2004 Natural history of nonalcoholic steatohepatitis: a longitudinal study of repeat liver biopsies Hepatology 40 820 826 15382171
30. KS Park YS Lee HW Park, et al. 2004 Factors associated or related to with pathological severity of nonalcoholic fatty liver disease Korean J Intern Med 19 19 26 15053039
31. M Fernandez D Semela J Bruix I Colle M Pinzani J Bosch 2009 Angiogenesis in liver disease J Hepatol 50 604 620 19157625 10.1016/j.jhep.2008.12.011 1:CAS:528:DC%2BD1MXhs1ekt7g%3D