Mammalian target of rapamycin mediates the angiogenic effects of leptin in human hepatic stellate cells

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 301, Issue 2, 2011, Pages

  Aleffi, Sara ^a   Navari, Nadia ^a   Delogu, Wanda ^a   Galastri, Sara ^a   Novo, Erica ^b   Rombouts, Krista ^a   Pinzani, Massimo ^a   Parola, Maurizio ^b   Marra, Fabio ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

Hepatic fibrosis; Hypoxia inducible factor; NADP(H) oxidase; Platelet derived growth factor

Indexed keywords

ACETYLCYSTEINE; DIPHENYLIODONIUM SALT; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PLATELET DERIVED GROWTH FACTOR; RAPAMYCIN; RAPTOR PROTEIN; REACTIVE OXYGEN METABOLITE; RECOMBINANT LEPTIN; S6 KINASE; THREONINE; TUBERIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MEDIATOR; MYOFIBROBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; STELLATE CELL;

CELL LINE; CELL MOVEMENT; HEP G2 CELLS; HEPATIC STELLATE CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LEPTIN; LIVER; NADPH OXIDASE; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; REACTIVE OXYGEN SPECIES; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79958069908     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00047.2010     Document Type: Article

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