-
1
-
-
84882336972
-
Diabetes and vascular disease: Pathophysiology, clinical consequences, and medical therapy: Part I
-
[I] Paneni, F.; Beckman, J.A.; Creager, M.A.; Cosentino, F. Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I. Eur. Heart J., 2013, 34(31), 2436-2443.
-
(2013)
Eur. Heart J.
, vol.34
, Issue.31
, pp. 2436-2443
-
-
Paneni, F.1
Beckman, J.A.2
Creager, M.A.3
Cosentino, F.4
-
2
-
-
84882354610
-
Diabetes and vascular disease: Pathophysiology, clinical consequences, and medical therapy: Part II
-
Beckman, J.A.; Paneni, F.; Cosentino, F.; Creager, M.A. Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part II. Eur. Heart J., 2013, 34(31), 2444-2452.
-
(2013)
Eur. Heart J.
, vol.34
, Issue.31
, pp. 2444-2452
-
-
Beckman, J.A.1
Paneni, F.2
Cosentino, F.3
Creager, M.A.4
-
3
-
-
78349297565
-
Oxidative stress and diabetic complications
-
Giacco, F.; Brownlee, M. Oxidative stress and diabetic complications. Circ. Res., 2010, 107(9), 1058-1070.
-
(2010)
Circ. Res.
, vol.107
, Issue.9
, pp. 1058-1070
-
-
Giacco, F.1
Brownlee, M.2
-
4
-
-
58149301489
-
Intensive glycemic control and the prevention of cardiovascular events: Implications of the ACCORD, ADVANCE, and VA Diabetes Trials: A position statement of the American Diabetes Association and a Scientific Statement of the American College of Cardiology Foundation and the American Heart Association
-
American College of Cardiology, F.; American Heart, A
-
Skyler, J.S.; Bergenstal, R.; Bonow, R.O.; Buse, J.; Deedwania, P.; Gale, E.A.; Howard, B.V.; Kirkman, M.S.; Kosiborod, M.; Reaven, P.; Sherwin, R.S.; American Diabetes, A.; American College of Cardiology, F.; American Heart, A. Intensive glycemic control and the prevention of cardiovascular events: implications of the ACCORD, ADVANCE, and VA Diabetes Trials: a position statement of the American Diabetes Association and a Scientific Statement of the American College of Cardiology Foundation and the American Heart Association. J. Am. Coll. Cardiol., 2009, 53(3), 298-304.
-
(2009)
J. Am. Coll. Cardiol.
, vol.53
, Issue.3
, pp. 298-304
-
-
Skyler, J.S.1
Bergenstal, R.2
Bonow, R.O.3
Buse, J.4
Deedwania, P.5
Gale, E.A.6
Howard, B.V.7
Kirkman, M.S.8
Kosiborod, M.9
Reaven, P.10
Sherwin, R.S.11
American Diabetes, A.12
-
5
-
-
79960959816
-
Effect of intensive glucose lowering treatment on all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes: Meta-analysis of randomised controlled trials
-
Boussageon, R.; Bejan-Angoulvant, T.; Saadatian-Elahi, M.; Lafont, S.; Bergeonneau, C.; Kassai, B.; Erpeldinger, S.; Wright, J.M.; Gueyffier, F.; Cornu, C. Effect of intensive glucose lowering treatment on all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes: meta-analysis of randomised controlled trials. BMJ, 2011, 343, d4169.
-
(2011)
BMJ
, vol.343
-
-
Boussageon, R.1
Bejan-Angoulvant, T.2
Saadatian-Elahi, M.3
Lafont, S.4
Bergeonneau, C.5
Kassai, B.6
Erpeldinger, S.7
Wright, J.M.8
Gueyffier, F.9
Cornu, C.10
-
6
-
-
84890453991
-
2013 ESC/EASD guidelines on the management of diabetes and cardiovascular disease: Established knowledge and evidence gaps
-
Paneni, F. 2013 ESC/EASD guidelines on the management of diabetes and cardiovascular disease: Established knowledge and evidence gaps. Diab. Vasc. Dis. Res., 2014, 11(1), 5-10.
-
(2014)
Diab. Vasc. Dis. Res.
, vol.11
, Issue.1
, pp. 5-10
-
-
Paneni, F.1
-
7
-
-
45149131667
-
Simons-Morton, D.G.; Friedewald, W.T. Effects of intensive glucose lowering in type 2 diabetes
-
Gerstein, H.C.; Miller, M.E.; Byington, R.P.; Goff, D.C., Jr.; Bigger, J.T.; Buse, J.B.; Cushman, W.C.; Genuth, S.; Ismail-Beigi, F.; Grimm, R.H., Jr.; Probstfield, J.L.; Simons-Morton, D.G.; Friedewald, W.T. Effects of intensive glucose lowering in type 2 diabetes. N. Engl. J. Med., 2008, 358(24), 2545-2559.
-
(2008)
N. Engl. J. Med.
, vol.358
, Issue.24
, pp. 2545-2559
-
-
Gerstein, H.C.1
Miller, M.E.2
Byington, R.P.3
Goff, D.C.4
Bigger, J.T.5
Buse, J.B.6
Cushman, W.C.7
Genuth, S.8
Ismail-Beigi, F.9
Grimm, R.H.10
Probstfield, J.L.11
-
8
-
-
45149133036
-
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
-
Patel, A.; MacMahon, S.; Chalmers, J.; Neal, B.; Billot, L.; Woodward, M.; Marre, M.; Cooper, M.; Glasziou, P.; Grobbee, D.; Hamet, P.; Harrap, S.; Heller, S.; Liu, L.; Mancia, G.; Mogensen, C.E.; Pan, C.; Poulter, N.; Rodgers, A.; Williams, B.; Bompoint, S.; de Galan, B.E.; Joshi, R.; Travert, F. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N. Engl. J. Med., 2008, 358(24), 2560-2572.
-
(2008)
N. Engl. J. Med.
, vol.358
, Issue.24
, pp. 2560-2572
-
-
Patel, A.1
Macmahon, S.2
Chalmers, J.3
Neal, B.4
Billot, L.5
Woodward, M.6
Marre, M.7
Cooper, M.8
Glasziou, P.9
Grobbee, D.10
Hamet, P.11
Harrap, S.12
Heller, S.13
Liu, L.14
Mancia, G.15
Mogensen, C.E.16
Pan, C.17
Poulter, N.18
Rodgers, A.19
Williams, B.20
Bompoint, S.21
De Galan, B.E.22
Joshi, R.23
Travert, F.24
more..
-
9
-
-
58149389215
-
Glucose control and vascular complications in veterans with type 2 diabetes
-
Duckworth, W.; Abraira, C.; Moritz, T.; Reda, D.; Emanuele, N.; Reaven, P.D.; Zieve, F.J.; Marks, J.; Davis, S.N.; Hayward, R.; Warren, S.R.; Goldman, S.; McCarren, M.; Vitek, M. E.; Henderson, W.G.; Huang, G.D. Glucose control and vascular complications in veterans with type 2 diabetes. N. Engl. J. Med., 2009, 360(2), 129-139.
-
(2009)
N. Engl. J. Med.
, vol.360
, Issue.2
, pp. 129-139
-
-
Duckworth, W.1
Abraira, C.2
Moritz, T.3
Reda, D.4
Emanuele, N.5
Reaven, P.D.6
Zieve, F.J.7
Marks, J.8
Davis, S.N.9
Hayward, R.10
Warren, S.R.11
Goldman, S.12
McCarren, M.13
Vitek, M.E.14
Henderson, W.G.15
Huang, G.D.16
-
10
-
-
59749094860
-
Clinical review 2: The "metabolic memory": Is more than just tight glucose control necessary to prevent diabetic complications
-
Ceriello, A.; Ihnat, M.A.; Thorpe, J.E. Clinical review 2: The "metabolic memory": Is more than just tight glucose control necessary to prevent diabetic complications? J. Clin. Endocrinol. Metab., 2009, 94(2), 410-415.
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, Issue.2
, pp. 410-415
-
-
Ceriello, A.1
Ihnat, M.A.2
Thorpe, J.E.3
-
11
-
-
78650694320
-
Epigenetics: Mechanisms and implications for diabetic complications
-
Cooper, M.E.; El-Osta, A. Epigenetics: Mechanisms and implications for diabetic complications. Circ. Res., 2010, 107(12), 1403-1413.
-
(2010)
Circ. Res.
, vol.107
, Issue.12
, pp. 1403-1413
-
-
Cooper, M.E.1
El-Osta, A.2
-
12
-
-
84901197713
-
Insulin resistance, diabetes, and cardiovascular risk
-
Paneni, F.; Costantino, S.; Cosentino, F. Insulin resistance, diabetes, and cardiovascular risk. Curr. Atheroscl. Rep., 2014, 16(7), 419.
-
(2014)
Curr. Atheroscl. Rep.
, vol.16
, Issue.7
, pp. 419
-
-
Paneni, F.1
Costantino, S.2
Cosentino, F.3
-
13
-
-
84872081425
-
Protein kinase C-beta contributes to impaired endothelial insulin signaling in humans with diabetes mellitus
-
Tabit, C.E.; Shenouda, S.M.; Holbrook, M.; Fetterman, J.L.; Kiani, S.; Frame, A.A.; Kluge, M.A.; Held, A.; Dohadwala, M.M.; Gokce, N.; Farb, M.G.; Rosenzweig, J.; Ruderman, N.; Vita, J.A.; Hamburg, N.M. Protein kinase C-beta contributes to impaired endothelial insulin signaling in humans with diabetes mellitus. Circulation, 2013, 127(1), 86-95.
-
(2013)
Circulation
, vol.127
, Issue.1
, pp. 86-95
-
-
Tabit, C.E.1
Shenouda, S.M.2
Holbrook, M.3
Fetterman, J.L.4
Kiani, S.5
Frame, A.A.6
Kluge, M.A.7
Held, A.8
Dohadwala, M.M.9
Gokce, N.10
Farb, M.G.11
Rosenzweig, J.12
Ruderman, N.13
Vita, J.A.14
Hamburg, N.M.15
-
14
-
-
33846817351
-
Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc
-
Pinton, P.; Rimessi, A.; Marchi, S.; Orsini, F.; Migliaccio, E.; Giorgio, M.; Contursi, C.; Minucci, S.; Mantovani, F.; Wieckowski, M.R.; Del Sal, G.; Pelicci, P.G.; Rizzuto, R. Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc. Science, 2007, 315(5812), 659-663.
-
(2007)
Science
, vol.315
, Issue.5812
, pp. 659-663
-
-
Pinton, P.1
Rimessi, A.2
Marchi, S.3
Orsini, F.4
Migliaccio, E.5
Giorgio, M.6
Contursi, C.7
Minucci, S.8
Mantovani, F.9
Wieckowski, M.R.10
Del Sal, G.11
Pelicci, P.G.12
Rizzuto, R.13
-
15
-
-
22744447211
-
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis
-
Giorgio, M.; Migliaccio, E.; Orsini, F.; Paolucci, D.; Moroni, M.; Contursi, C.; Pelliccia, G.; Luzi, L.; Minucci, S.; Marcaccio, M.; Pinton, P.; Rizzuto, R.; Bernardi, P.; Paolucci, F.; Pelicci, P.G. Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis. Cell, 2005, 122(2), 221-233.
-
(2005)
Cell
, vol.122
, Issue.2
, pp. 221-233
-
-
Giorgio, M.1
Migliaccio, E.2
Orsini, F.3
Paolucci, D.4
Moroni, M.5
Contursi, C.6
Pelliccia, G.7
Luzi, L.8
Minucci, S.9
Marcaccio, M.10
Pinton, P.11
Rizzuto, R.12
Bernardi, P.13
Paolucci, F.14
Pelicci, P.G.15
-
16
-
-
34247596394
-
Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress
-
Camici, G.G.; Schiavoni, M.; Francia, P.; Bachschmid, M.; Martin-Padura, I.; Hersberger, M.; Tanner, F.C.; Pelicci, P.; Volpe, M.; Anversa, P.; Luscher, T.F.; Cosentino, F. Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress. Proc. Natl. Acad. Sci. USA, 2007, 104(12), 5217-5222.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, Issue.12
, pp. 5217-5222
-
-
Camici, G.G.1
Schiavoni, M.2
Francia, P.3
Bachschmid, M.4
Martin-Padura, I.5
Hersberger, M.6
Tanner, F.C.7
Pelicci, P.8
Volpe, M.9
Anversa, P.10
Luscher, T.F.11
Cosentino, F.12
-
17
-
-
14044254273
-
Diabetes induces p66shc gene expression in human peripheral blood mononuclear cells: Relationship to oxidative stress
-
Pagnin, E.; Fadini, G.; de Toni, R.; Tiengo, A.; Calo, L.; Avogaro, A. Diabetes induces p66shc gene expression in human peripheral blood mononuclear cells: relationship to oxidative stress. J. Clin. Endocrinol. Metab., 2005, 90(2), 1130-1136.
-
(2005)
J. Clin. Endocrinol. Metab.
, vol.90
, Issue.2
, pp. 1130-1136
-
-
Pagnin, E.1
Fadini, G.2
De Toni, R.3
Tiengo, A.4
Calo, L.5
Avogaro, A.6
-
18
-
-
84864210978
-
Gene silencing of the mitochondrial adaptor p66(Shc) suppresses vascular hyperglycemic memory in diabetes
-
Paneni, F.; Mocharla, P.; Akhmedov, A.; Costantino, S.; Osto, E.; Volpe, M.; Luscher, T.F.; Cosentino, F. Gene silencing of the mitochondrial adaptor p66(Shc) suppresses vascular hyperglycemic memory in diabetes. Circ. Res., 2012, 111(3), 278-289.
-
(2012)
Circ. Res.
, vol.111
, Issue.3
, pp. 278-289
-
-
Paneni, F.1
Mocharla, P.2
Akhmedov, A.3
Costantino, S.4
Osto, E.5
Volpe, M.6
Luscher, T.F.7
Cosentino, F.8
-
19
-
-
78650878363
-
NF-kappaB, inflammation, and metabolic disease
-
Baker, R.G.; Hayden, M.S.; Ghosh, S. NF-kappaB, inflammation, and metabolic disease. Cell Metab., 2011, 13(1), 11-22.
-
(2011)
Cell Metab.
, vol.13
, Issue.1
, pp. 11-22
-
-
Baker, R.G.1
Hayden, M.S.2
Ghosh, S.3
-
20
-
-
84857914467
-
Blockade of the nuclear factor-kappaB pathway in the endothelium prevents insulin resistance and prolongs life spans
-
Hasegawa, Y.; Saito, T.; Ogihara, T.; Ishigaki, Y.; Yamada, T.; Imai, J.; Uno, K.; Gao, J.; Kaneko, K.; Shimosawa, T.; Asano, T.; Fujita, T.; Oka, Y.; Katagiri, H. Blockade of the nuclear factor-kappaB pathway in the endothelium prevents insulin resistance and prolongs life spans. Circulation, 2012, 125(9), 1122-1133.
-
(2012)
Circulation
, vol.125
, Issue.9
, pp. 1122-1133
-
-
Hasegawa, Y.1
Saito, T.2
Ogihara, T.3
Ishigaki, Y.4
Yamada, T.5
Imai, J.6
Uno, K.7
Gao, J.8
Kaneko, K.9
Shimosawa, T.10
Asano, T.11
Fujita, T.12
Oka, Y.13
Katagiri, H.14
-
21
-
-
84907073942
-
P66(Shc)-induced redox changes drive endothelial insulin resistance
-
Paneni, F.; Costantino, S.; Cosentino, F. p66(Shc)-induced redox changes drive endothelial insulin resistance. Atherosclerosis, 2014, 236(2), 426-429.
-
(2014)
Atherosclerosis
, vol.236
, Issue.2
, pp. 426-429
-
-
Paneni, F.1
Costantino, S.2
Cosentino, F.3
-
22
-
-
84926674364
-
Targeting prolyl-isomerase Pin1 prevents mitochondrial oxidative stress and vascular dysfunction: Insights in patients with diabetes
-
Paneni, F.; Costantino, S.; Castello, L.; Battista, R.; Capretti, G.; Chiandotto, S.; D'Amario, D.; Scavone, G.; Villano, A.; Rustighi, A.; Crea, F.; Pitocco, D.; Lanza, G.; Volpe, M.; Del Sal, G.; Luscher, T.F.; Cosentino, F. Targeting prolyl-isomerase Pin1 prevents mitochondrial oxidative stress and vascular dysfunction: insights in patients with diabetes. Eur. Heart J., 2014, 10.1093/eurheartj/ehu179.
-
(2014)
Eur. Heart J
-
-
Paneni, F.1
Costantino, S.2
Castello, L.3
Battista, R.4
Capretti, G.5
Chiandotto, S.6
D'amario, D.7
Scavone, G.8
Villano, A.9
Rustighi, A.10
Crea, F.11
Pitocco, D.12
Lanza, G.13
Volpe, M.14
Del Sal, G.15
Luscher, T.F.16
Cosentino, F.17
-
23
-
-
73349092441
-
Histones: Annotating chromatin
-
Campos, E.I.; Reinberg, D. Histones: Annotating chromatin. Annu. Rev. Genet., 2009, 43, 559-599.
-
(2009)
Annu. Rev. Genet.
, vol.43
, pp. 559-599
-
-
Campos, E.I.1
Reinberg, D.2
-
24
-
-
1842411320
-
Crystal structure of the nucleosome core particle at 2.8 A resolution
-
Luger, K.; Mader, A.W.; Richmond, R.K.; Sargent, D.F.; Richmond, T.J. Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature, 1997, 389(6648), 251-260.
-
(1997)
Nature
, vol.389
, Issue.6648
, pp. 251-260
-
-
Luger, K.1
Mader, A.W.2
Richmond, R.K.3
Sargent, D.F.4
Richmond, T.J.5
-
25
-
-
33847070442
-
The role of chromatin during transcription
-
Li, B.; Carey, M.; Workman, J.L. The role of chromatin during transcription. Cell, 2007, 128(4), 707-719.
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 707-719
-
-
Li, B.1
Carey, M.2
Workman, J.L.3
-
26
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides, T. Chromatin modifications and their function. Cell, 2007, 128(4), 693-705.
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 693-705
-
-
Kouzarides, T.1
-
27
-
-
84876135208
-
The role of redox signaling in epigenetics and cardiovascular disease
-
Kim, G.H.; Ryan, J.J.; Archer, S.L. The role of redox signaling in epigenetics and cardiovascular disease. Antioxid. Redox Signal., 2013, 18(15), 1920-1936.
-
(2013)
Antioxid. Redox Signal.
, vol.18
, Issue.15
, pp. 1920-1936
-
-
Kim, G.H.1
Ryan, J.J.2
Archer, S.L.3
-
28
-
-
84884562282
-
Epigenetic signatures and vascular risk in type 2 diabetes: A clinical perspective
-
Paneni, F.; Costantino, S.; Volpe, M.; Luscher, T.F.; Cosentino, F. Epigenetic signatures and vascular risk in type 2 diabetes: A clinical perspective. Atherosclerosis, 2013, 230(2), 191-197.
-
(2013)
Atherosclerosis
, vol.230
, Issue.2
, pp. 191-197
-
-
Paneni, F.1
Costantino, S.2
Volpe, M.3
Luscher, T.F.4
Cosentino, F.5
-
29
-
-
33847032960
-
The mammalian epigenome
-
Bernstein, B.E.; Meissner, A.; Lander, E.S. The mammalian epigenome. Cell, 2007, 128(4), 669-681.
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 669-681
-
-
Bernstein, B.E.1
Meissner, A.2
Lander, E.S.3
-
30
-
-
0034625064
-
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a
-
Ramsahoye, B.H.; Biniszkiewicz, D.; Lyko, F.; Clark, V.; Bird, A.P.; Jaenisch, R. Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc. Natl. Acad. Sci. USA, 2000, 97(10), 5237-5242.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, Issue.10
, pp. 5237-5242
-
-
Ramsahoye, B.H.1
Biniszkiewicz, D.2
Lyko, F.3
Clark, V.4
Bird, A.P.5
Jaenisch, R.6
-
31
-
-
84862127099
-
Environmental exposures, epigenetics and cardiovascular disease
-
Baccarelli, A.; Ghosh, S. Environmental exposures, epigenetics and cardiovascular disease. Curr. Opin. Clin. Nutr. Metab. Care, 2012, 15(4), 323-329.
-
(2012)
Curr. Opin. Clin. Nutr. Metab. Care
, vol.15
, Issue.4
, pp. 323-329
-
-
Baccarelli, A.1
Ghosh, S.2
-
32
-
-
79957463780
-
Epigenetic modifications: Basic mechanisms and role in cardiovascular disease
-
Handy, D.E.; Castro, R.; Loscalzo, J. Epigenetic modifications: basic mechanisms and role in cardiovascular disease. Circulation, 2011, 123(19), 2145-2156.
-
(2011)
Circulation
, vol.123
, Issue.19
, pp. 2145-2156
-
-
Handy, D.E.1
Castro, R.2
Loscalzo, J.3
-
33
-
-
34848911647
-
DNA methylation: The nuts and bolts of repression
-
Miranda, T.B.; Jones, P.A. DNA methylation: the nuts and bolts of repression. J. Cell. Physiol., 2007, 213(2), 384-390.
-
(2007)
J. Cell. Physiol.
, vol.213
, Issue.2
, pp. 384-390
-
-
Miranda, T.B.1
Jones, P.A.2
-
34
-
-
42549126341
-
Epigenetic regulation of vascular endothelial gene expression
-
Matouk, C.C.; Marsden, P.A. Epigenetic regulation of vascular endothelial gene expression. Circ. Res., 2008, 102(8), 873-887.
-
(2008)
Circ. Res.
, vol.102
, Issue.8
, pp. 873-887
-
-
Matouk, C.C.1
Marsden, P.A.2
-
35
-
-
73249133400
-
Epigenetics: A molecular link between environmental factors and type 2 diabetes
-
Ling, C.; Groop, L. Epigenetics: A molecular link between environmental factors and type 2 diabetes. Diabetes, 2009, 58(12), 2718-2725.
-
(2009)
Diabetes
, vol.58
, Issue.12
, pp. 2718-2725
-
-
Ling, C.1
Groop, L.2
-
36
-
-
77956095231
-
Active DNA demethylation: Many roads lead to Rome
-
Wu, S.C.; Zhang, Y. Active DNA demethylation: many roads lead to Rome. Nat. Rev. Mol. Cell. Biol., 2010, 11(9), 607-620.
-
(2010)
Nat. Rev. Mol. Cell. Biol.
, vol.11
, Issue.9
, pp. 607-620
-
-
Wu, S.C.1
Zhang, Y.2
-
37
-
-
84870152439
-
5-Methylcytosine DNA demethylation: More than losing a methyl group
-
Franchini, D.M.; Schmitz, K.M.; Petersen-Mahrt, S.K. 5-Methylcytosine DNA demethylation: more than losing a methyl group. Annu. Rev. Genet., 2012, 46, 419-441.
-
(2012)
Annu. Rev. Genet.
, vol.46
, pp. 419-441
-
-
Franchini, D.M.1
Schmitz, K.M.2
Petersen-Mahrt, S.K.3
-
38
-
-
84886860116
-
TET enzymes, TDG and the dynamics of DNA demethylation
-
Kohli, R.M.; Zhang, Y. TET enzymes, TDG and the dynamics of DNA demethylation. Nature, 2013, 502(7472), 472-479.
-
(2013)
Nature
, vol.502
, Issue.7472
, pp. 472-479
-
-
Kohli, R.M.1
Zhang, Y.2
-
39
-
-
27644589675
-
The diverse functions of histone lysine methylation
-
Martin, C.; Zhang, Y. The diverse functions of histone lysine methylation. Nat. Rev. Mol. Cell Biol., 2005, 6(11), 838-849.
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, Issue.11
, pp. 838-849
-
-
Martin, C.1
Zhang, Y.2
-
40
-
-
0035839136
-
Translating the histone code
-
Jenuwein, T.; Allis, C.D. Translating the histone code. Science, 2001, 293(5532), 1074-1080.
-
(2001)
Science
, vol.293
, Issue.5532
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
41
-
-
34547890019
-
Functions of site-specific histone acetylation and deacetylation
-
Shahbazian, M.D.; Grunstein, M. Functions of site-specific histone acetylation and deacetylation. Annu. Rev. Biochem., 2007, 76, 75-100.
-
(2007)
Annu. Rev. Biochem.
, vol.76
, pp. 75-100
-
-
Shahbazian, M.D.1
Grunstein, M.2
-
42
-
-
57749170458
-
The many roles of histone deacetylases in development and physiology: Implications for disease and therapy
-
Haberland, M.; Montgomery, R.L.; Olson, E.N. The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat. Rev. Genet., 2009, 10(1), 32-42.
-
(2009)
Nat. Rev. Genet.
, vol.10
, Issue.1
, pp. 32-42
-
-
Haberland, M.1
Montgomery, R.L.2
Olson, E.N.3
-
43
-
-
84862182267
-
Epigenetic regulation in obesity
-
Lavebratt, C.; Almgren, M.; Ekstrom, T.J. Epigenetic regulation in obesity. Int. J. Obes., 2012, 36(6), 757-765.
-
(2012)
Int. J. Obes.
, vol.36
, Issue.6
, pp. 757-765
-
-
Lavebratt, C.1
Almgren, M.2
Ekstrom, T.J.3
-
44
-
-
33748451151
-
Anticancer activities of histone deacetylase inhibitors
-
Bolden, J.E.; Peart, M.J.; Johnstone, R.W. Anticancer activities of histone deacetylase inhibitors. Nat. Rev. Drug Discov., 2006, 5(9), 769-784.
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, Issue.9
, pp. 769-784
-
-
Bolden, J.E.1
Peart, M.J.2
Johnstone, R.W.3
-
45
-
-
0344407016
-
Histone deacetylases: Unique players in shaping the epigenetic histone code
-
Thiagalingam, S.; Cheng, K.H.; Lee, H.J.; Mineva, N.; Thiagalingam, A.; Ponte, J.F. Histone deacetylases: unique players in shaping the epigenetic histone code. Ann. NY Acad. Sci., 2003, 983, 84-100.
-
(2003)
Ann. NY Acad. Sci.
, vol.983
, pp. 84-100
-
-
Thiagalingam, S.1
Cheng, K.H.2
Lee, H.J.3
Mineva, N.4
Thiagalingam, A.5
Ponte, J.F.6
-
46
-
-
24144475284
-
Reversing histone methylation
-
Bannister, A.J.; Kouzarides, T. Reversing histone methylation. Nature, 2005, 436(7054), 1103-1106.
-
(2005)
Nature
, vol.436
, Issue.7054
, pp. 1103-1106
-
-
Bannister, A.J.1
Kouzarides, T.2
-
47
-
-
11144332565
-
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
-
Shi, Y.; Lan, F.; Matson, C.; Mulligan, P.; Whetstine, J.R.; Cole, P.A.; Casero, R.A.; Shi, Y. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell, 2004, 119(7), 941-953.
-
(2004)
Cell
, vol.119
, Issue.7
, pp. 941-953
-
-
Shi, Y.1
Lan, F.2
Matson, C.3
Mulligan, P.4
Whetstine, J.R.5
Cole, P.A.6
Casero, R.A.7
Shi, Y.8
-
48
-
-
24144462170
-
LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription
-
Metzger, E.; Wissmann, M.; Yin, N.; Muller, J.M.; Schneider, R.; Peters, A.H.; Gunther, T.; Buettner, R.; Schule, R. LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription. Nature, 2005, 437(7057), 436-439.
-
(2005)
Nature
, vol.437
, Issue.7057
, pp. 436-439
-
-
Metzger, E.1
Wissmann, M.2
Yin, N.3
Muller, J.M.4
Schneider, R.5
Peters, A.H.6
Gunther, T.7
Buettner, R.8
Schule, R.9
-
49
-
-
77953860649
-
The role of epigenetics in the pathology of diabetic complications
-
Villeneuve, L.M.; Natarajan, R. The role of epigenetics in the pathology of diabetic complications. Am. J. Physiol. Renal Physiol., 2010, 299(1), F14-25.
-
(2010)
Am. J. Physiol. Renal Physiol.
, vol.299
, Issue.1
, pp. F14-F25
-
-
Villeneuve, L.M.1
Natarajan, R.2
-
50
-
-
33646124469
-
Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases
-
Whetstine, J.R.; Nottke, A.; Lan, F.; Huarte, M.; Smolikov, S.; Chen, Z.; Spooner, E.; Li, E.; Zhang, G.; Colaiacovo, M.; Shi, Y. Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases. Cell, 2006, 125(3), 467-481.
-
(2006)
Cell
, vol.125
, Issue.3
, pp. 467-481
-
-
Whetstine, J.R.1
Nottke, A.2
Lan, F.3
Huarte, M.4
Smolikov, S.5
Chen, Z.6
Spooner, E.7
Li, E.8
Zhang, G.9
Colaiacovo, M.10
Shi, Y.11
-
51
-
-
64749111074
-
Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
-
Tateishi, K.; Okada, Y.; Kallin, E. M.; Zhang, Y. Role of Jhdm2a in regulating metabolic gene expression and obesity resistance. Nature, 2009, 458(7239), 757-761.
-
(2009)
Nature
, vol.458
, Issue.7239
, pp. 757-761
-
-
Tateishi, K.1
Okada, Y.2
Kallin, E.M.3
Zhang, Y.4
-
52
-
-
0034458963
-
Genomic targeting of methylated DNA: Influence of methylation on transcription, replication, chromatin structure, and histone acetylation
-
Schubeler, D.; Lorincz, M.C.; Cimbora, D.M.; Telling, A.; Feng, Y.Q.; Bouhassira, E.E.; Groudine, M. Genomic targeting of methylated DNA: influence of methylation on transcription, replication, chromatin structure, and histone acetylation. Mol. Cell. Biol., 2000, 20(24), 9103-9112.
-
(2000)
Mol. Cell. Biol.
, vol.20
, Issue.24
, pp. 9103-9112
-
-
Schubeler, D.1
Lorincz, M.C.2
Cimbora, D.M.3
Telling, A.4
Feng, Y.Q.5
Bouhassira, E.E.6
Groudine, M.7
-
53
-
-
67349190247
-
Linking DNA methylation and histone modification: Patterns and paradigms
-
Cedar, H.; Bergman, Y. Linking DNA methylation and histone modification: patterns and paradigms. Nat. Rev. Genet., 2009, 10(5), 295-304.
-
(2009)
Nat. Rev. Genet.
, vol.10
, Issue.5
, pp. 295-304
-
-
Cedar, H.1
Bergman, Y.2
-
54
-
-
77950624912
-
Epigenetic mechanisms in the development of type 2 diabetes
-
Pinney, S.E.; Simmons, R.A. Epigenetic mechanisms in the development of type 2 diabetes. Trends Endocrinol. Metab., 2010, 21(4), 223-229.
-
(2010)
Trends Endocrinol. Metab.
, vol.21
, Issue.4
, pp. 223-229
-
-
Pinney, S.E.1
Simmons, R.A.2
-
55
-
-
33847065486
-
The epigenomics of cancer
-
Jones, P.A.; Baylin, S.B. The epigenomics of cancer. Cell, 2007, 128(4), 683-692.
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
56
-
-
79955055958
-
Epigenetics in cardiovascular disease
-
Shirodkar, A.V.; Marsden, P.A. Epigenetics in cardiovascular disease. Curr. Opin. Cardiol., 2011, 26(3), 209-215.
-
(2011)
Curr. Opin. Cardiol.
, vol.26
, Issue.3
, pp. 209-215
-
-
Shirodkar, A.V.1
Marsden, P.A.2
-
57
-
-
3142672297
-
DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein
-
Lund, G.; Andersson, L.; Lauria, M.; Lindholm, M.; Fraga, M.F.; Villar-Garea, A.; Ballestar, E.; Esteller, M.; Zaina, S. DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E. J. Biol. Chem., 2004, 279(28), 29147-29154.
-
(2004)
E. J. Biol. Chem.
, vol.279
, Issue.28
, pp. 29147-29154
-
-
Lund, G.1
Andersson, L.2
Lauria, M.3
Lindholm, M.4
Fraga, M.F.5
Villar-Garea, A.6
Ballestar, E.7
Esteller, M.8
Zaina, S.9
-
58
-
-
0037326196
-
Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): Transcriptional coactivator and metabolic regulator
-
Puigserver, P.; Spiegelman, B.M. Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. Endocr. Rev., 2003, 24(1), 78-90.
-
(2003)
Endocr. Rev.
, vol.24
, Issue.1
, pp. 78-90
-
-
Puigserver, P.1
Spiegelman, B.M.2
-
59
-
-
39049137496
-
Role of PPAR in cardiovascular diseases
-
Das, S.K.; Chakrabarti, R. Role of PPAR in cardiovascular diseases. Recent Pat. Cardiovasc. Drug Discov., 2006, 1(2), 193-209.
-
(2006)
Recent Pat. Cardiovasc. Drug Discov.
, vol.1
, Issue.2
, pp. 193-209
-
-
Das, S.K.1
Chakrabarti, R.2
-
60
-
-
41149172495
-
Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion
-
Ling, C.; Del Guerra, S.; Lupi, R.; Ronn, T.; Granhall, C.; Luthman, H.; Masiello, P.; Marchetti, P.; Groop, L.; Del Prato, S. Epigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretion. Diabetologia, 2008, 51(4), 615-622.
-
(2008)
Diabetologia
, vol.51
, Issue.4
, pp. 615-622
-
-
Ling, C.1
Del Guerra, S.2
Lupi, R.3
Ronn, T.4
Granhall, C.5
Luthman, H.6
Masiello, P.7
Marchetti, P.8
Groop, L.9
Del Prato, S.10
-
61
-
-
74049085411
-
Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones
-
Fish, J.E.; Yan, M.S.; Matouk, C.C.; St Bernard, R.; Ho, J.J.; Gavryushova, A.; Srivastava, D.; Marsden, P.A. Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones. J. Biol. Chem., 2010, 285(2), 810-826.
-
(2010)
J. Biol. Chem.
, vol.285
, Issue.2
, pp. 810-826
-
-
Fish, J.E.1
Yan, M.S.2
Matouk, C.C.3
St Bernard, R.4
Ho, J.J.5
Gavryushova, A.6
Srivastava, D.7
Marsden, P.A.8
-
62
-
-
33749494456
-
Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells
-
Chen, H.; Yan, Y.; Davidson, T.L.; Shinkai, Y.; Costa, M. Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells. Cancer Res., 2006, 66(18), 9009-9016.
-
(2006)
Cancer Res.
, vol.66
, Issue.18
, pp. 9009-9016
-
-
Chen, H.1
Yan, Y.2
Davidson, T.L.3
Shinkai, Y.4
Costa, M.5
-
63
-
-
35549008884
-
SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase
-
Mattagajasingh, I.; Kim, C.S.; Naqvi, A.; Yamamori, T.; Hoffman, T.A.; Jung, S.B.; DeRicco, J.; Kasuno, K.; Irani, K. SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase. Proc. Natl. Acad. Sci. USA, 2007, 104(37), 14855-14860.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, Issue.37
, pp. 14855-14860
-
-
Mattagajasingh, I.1
Kim, C.S.2
Naqvi, A.3
Yamamori, T.4
Hoffman, T.A.5
Jung, S.B.6
Dericco, J.7
Kasuno, K.8
Irani, K.9
-
64
-
-
24744438447
-
Epigenetic basis for the transcriptional hyporesponsiveness of the human inducible nitric oxide synthase gene in vascular endothelial cells
-
Chan, G.C.; Fish, J.E.; Mawji, I.A.; Leung, D.D.; Rachlis, A.C.; Marsden, P.A. Epigenetic basis for the transcriptional hyporesponsiveness of the human inducible nitric oxide synthase gene in vascular endothelial cells. J. Immunol., 2005, 175(6), 3846-3861.
-
(2005)
J. Immunol.
, vol.175
, Issue.6
, pp. 3846-3861
-
-
Chan, G.C.1
Fish, J.E.2
Mawji, I.A.3
Leung, D.D.4
Rachlis, A.C.5
Marsden, P.A.6
-
65
-
-
79957487252
-
Epigenetic mechanisms in diabetic vascular complications
-
Reddy, M.A.; Natarajan, R. Epigenetic mechanisms in diabetic vascular complications. Cardiovasc. Res., 2011, 90(3), 421-429.
-
(2011)
Cardiovasc. Res.
, vol.90
, Issue.3
, pp. 421-429
-
-
Reddy, M.A.1
Natarajan, R.2
-
66
-
-
81255162523
-
Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands
-
O'Hagan, H.M.; Wang, W.; Sen, S.; Destefano Shields, C.; Lee, S.S.; Zhang, Y.W.; Clements, E.G.; Cai, Y.; Van Neste, L.; Easwaran, H.; Casero, R.A.; Sears, C.L.; Baylin, S.B. Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands. Cancer Cell, 2011, 20(5), 606-619.
-
(2011)
Cancer Cell
, vol.20
, Issue.5
, pp. 606-619
-
-
O'hagan, H.M.1
Wang, W.2
Sen, S.3
Destefano Shields, C.4
Lee, S.S.5
Zhang, Y.W.6
Clements, E.G.7
Cai, Y.8
Van Neste, L.9
Easwaran, H.10
Casero, R.A.11
Sears, C.L.12
Baylin, S.B.13
-
67
-
-
11844286970
-
Nutrition and aberrant DNA methylation patterns in atherosclerosis: More than just hyperhomocysteinemia
-
Zaina, S.; Lindholm, M.W.; Lund, G. Nutrition and aberrant DNA methylation patterns in atherosclerosis: more than just hyperhomocysteinemia? J. Nutr., 2005, 135(1), 5-8.
-
(2005)
J. Nutr.
, vol.135
, Issue.1
, pp. 5-8
-
-
Zaina, S.1
Lindholm, M.W.2
Lund, G.3
-
68
-
-
67249155691
-
High fat diet-induced obesity modifies the methylation pattern of leptin promoter in rats
-
Milagro, F.I.; Campion, J.; Garcia-Diaz, D.F.; Goyenechea, E.; Paternain, L.; Martinez, J.A. High fat diet-induced obesity modifies the methylation pattern of leptin promoter in rats. J. Physiol. Biochem., 2009, 65(1), 1-9.
-
(2009)
J. Physiol. Biochem.
, vol.65
, Issue.1
, pp. 1-9
-
-
Milagro, F.I.1
Campion, J.2
Garcia-Diaz, D.F.3
Goyenechea, E.4
Paternain, L.5
Martinez, J.A.6
-
69
-
-
0032846947
-
Local hypomethylation in atherosclerosis found in rabbit ec-SOD gene
-
Laukkanen, M.O.; Mannermaa, S.; Hiltunen, M.O.; Aittomaki, S.; Airenne, K.; Janne, J.; Yla-Herttuala, S. Local hypomethylation in atherosclerosis found in rabbit ec-SOD gene. Arterioscler. Thromb. Vasc. Biol., 1999, 19(9), 2171-2178.
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, Issue.9
, pp. 2171-2178
-
-
Laukkanen, M.O.1
Mannermaa, S.2
Hiltunen, M.O.3
Aittomaki, S.4
Airenne, K.5
Janne, J.6
Yla-Herttuala, S.7
-
70
-
-
34250303104
-
Genome-wide analysis of histone lysine methylation variations caused by diabetic conditions in human monocytes
-
Miao, F.; Wu, X.; Zhang, L.; Yuan, Y.C.; Riggs, A.D.; Natarajan, R. Genome-wide analysis of histone lysine methylation variations caused by diabetic conditions in human monocytes. J. Biol. Chem., 2007, 282(18), 13854-13863.
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.18
, pp. 13854-13863
-
-
Miao, F.1
Wu, X.2
Zhang, L.3
Yuan, Y.C.4
Riggs, A.D.5
Natarajan, R.6
-
71
-
-
58149345088
-
Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: An epigenetic study in diabetes
-
Miao, F.; Smith, D.D.; Zhang, L.; Min, A.; Feng, W.; Natarajan, R. Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: An epigenetic study in diabetes. Diabetes, 2008, 57(12), 3189-3198.
-
(2008)
Diabetes
, vol.57
, Issue.12
, pp. 3189-3198
-
-
Miao, F.1
Smith, D.D.2
Zhang, L.3
Min, A.4
Feng, W.5
Natarajan, R.6
-
72
-
-
33750589423
-
Enhanced proatherogenic responses in macrophages and vascular smooth muscle cells derived from diabetic db/db mice
-
Li, S.L.; Reddy, M.A.; Cai, Q.; Meng, L.; Yuan, H.; Lanting, L.; Natarajan, R. Enhanced proatherogenic responses in macrophages and vascular smooth muscle cells derived from diabetic db/db mice. Diabetes, 2006, 55(9), 2611-2619.
-
(2006)
Diabetes
, vol.55
, Issue.9
, pp. 2611-2619
-
-
Li, S.L.1
Reddy, M.A.2
Cai, Q.3
Meng, L.4
Yuan, H.5
Lanting, L.6
Natarajan, R.7
-
73
-
-
0033037930
-
Hyperglycemia-induced activation of nuclear transcription factor kappaB in vascular smooth muscle cells
-
Yerneni, K.K.; Bai, W.; Khan, B.V.; Medford, R.M.; Natarajan, R. Hyperglycemia-induced activation of nuclear transcription factor kappaB in vascular smooth muscle cells. Diabetes, 1999, 48(4), 855-864.
-
(1999)
Diabetes
, vol.48
, Issue.4
, pp. 855-864
-
-
Yerneni, K.K.1
Bai, W.2
Khan, B.V.3
Medford, R.M.4
Natarajan, R.5
-
74
-
-
65549170303
-
Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail
-
Brasacchio, D.; Okabe, J.; Tikellis, C.; Balcerczyk, A.; George, P.; Baker, E.K.; Calkin, A.C.; Brownlee, M.; Cooper, M.E.; El-Osta, A. Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail. Diabetes, 2009, 58(5), 1229-1236.
-
(2009)
Diabetes
, vol.58
, Issue.5
, pp. 1229-1236
-
-
Brasacchio, D.1
Okabe, J.2
Tikellis, C.3
Balcerczyk, A.4
George, P.5
Baker, E.K.6
Calkin, A.C.7
Brownlee, M.8
Cooper, M.E.9
El-Osta, A.10
-
75
-
-
64549158030
-
Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemiaJ. Exp. Med
-
El-Osta, A.; Brasacchio, D.; Yao, D.; Pocai, A.; Jones, P.L.; Roeder, R.G.; Cooper, M.E.; Brownlee, M. Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. J. Exp. Med., 2008, 205(10), 2409-2417.
-
(2008)
J. Exp. Med.
, vol.205
, Issue.10
, pp. 2409-2417
-
-
El-Osta, A.1
Brasacchio, D.2
Yao, D.3
Pocai, A.4
Jones, P.L.5
Roeder, R.G.6
Cooper, M.E.7
Brownlee, M.8
-
76
-
-
84929045419
-
Transcriptional regulation by the Set7 lysine methyltransferase
-
Keating, S.T.; El-Osta, A. Transcriptional regulation by the Set7 lysine methyltransferase. Epigenetics, 2013, 8(4), 361-372.
-
(2013)
Epigenetics
, vol.8
, Issue.4
, pp. 361-372
-
-
Keating, S.T.1
El-Osta, A.2
-
77
-
-
55549140173
-
Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-kappaB-dependent inflammatory genes. Relevance to diabetes and inflammation
-
Li, Y.; Reddy, M.A.; Miao, F.; Shanmugam, N.; Yee, J.K.; Hawkins, D.; Ren, B.; Natarajan, R. Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-kappaB-dependent inflammatory genes. Relevance to diabetes and inflammation. J. Biol. Chem., 2008, 283(39), 26771-26781.
-
(2008)
J. Biol. Chem.
, vol.283
, Issue.39
, pp. 26771-26781
-
-
Li, Y.1
Reddy, M.A.2
Miao, F.3
Shanmugam, N.4
Yee, J.K.5
Hawkins, D.6
Ren, B.7
Natarajan, R.8
-
78
-
-
84924627239
-
Adverse Epigenetic signatures by histone methyltransferase set7 contribute to vascular dysfunction in patients with type 2 diabetes
-
Paneni, F.; Costantino, S.; Battista, R.; Castello, L.; Capretti, G.; Chiandotto, S.; Scavone, G.; Villano, A.; Pitocco, D.; Lanza, G.; Volpe, M.; Luscher, T.F.; Cosentino, F. Adverse Epigenetic signatures by histone methyltransferase set7 contribute to vascular dysfunction in patients with type 2 diabetes. Circ. Cardiovasc. Genet., 2014, 8(1), 150-158.
-
(2014)
Circ. Cardiovasc. Genet.
, vol.8
, Issue.1
, pp. 150-158
-
-
Paneni, F.1
Costantino, S.2
Battista, R.3
Castello, L.4
Capretti, G.5
Chiandotto, S.6
Scavone, G.7
Villano, A.8
Pitocco, D.9
Lanza, G.10
Volpe, M.11
Luscher, T.F.12
Cosentino, F.13
-
79
-
-
48249127225
-
Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes
-
Villeneuve, L.M.; Reddy, M.A.; Lanting, L.L.; Wang, M.; Meng, L.; Natarajan, R. Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes. Proc. Natl. Acad. Sci. USA, 2008, 105(26), 9047-9052.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, Issue.26
, pp. 9047-9052
-
-
Villeneuve, L.M.1
Reddy, M.A.2
Lanting, L.L.3
Wang, M.4
Meng, L.5
Natarajan, R.6
-
80
-
-
2342423022
-
In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions
-
Miao, F.; Gonzalo, I.G.; Lanting, L.; Natarajan, R. In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions. J. Biol. Chem., 2004, 279(17), 18091-18097.
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.17
, pp. 18091-18097
-
-
Miao, F.1
Gonzalo, I.G.2
Lanting, L.3
Natarajan, R.4
-
81
-
-
66349101373
-
Protective role of SIRT1 in diabetic vascular dysfunction. Arterioscler
-
Orimo, M.; Minamino, T.; Miyauchi, H.; Tateno, K.; Okada, S.; Moriya, J.; Komuro, I. Protective role of SIRT1 in diabetic vascular dysfunction. Arterioscler. Thromb. Vasc. Biol., 2009, 29(6), 889-894.
-
(2009)
Thromb. Vasc. Biol.
, vol.29
, Issue.6
, pp. 889-894
-
-
Orimo, M.1
Minamino, T.2
Miyauchi, H.3
Tateno, K.4
Okada, S.5
Moriya, J.6
Komuro, I.7
-
82
-
-
84878225283
-
SIRT1, p66Shc, and Set7/9 in vascular hyperglycemic memory
-
Paneni, F.; Volpe, M.; Luscher, T.F.; Cosentino, F. SIRT1, p66Shc, and Set7/9 in vascular hyperglycemic memory: Bringing all the strands together. Diabetes, 2013, 62(6), 1800-1807.
-
(2013)
Bringing All the Strands Together. Diabetes
, vol.62
, Issue.6
, pp. 1800-1807
-
-
Paneni, F.1
Volpe, M.2
Luscher, T.F.3
Cosentino, F.4
-
83
-
-
84926637230
-
Cosentino, F. Molecular mechanisms of vascular dysfunction and cardiovascular biomarkers in type 2 diabetes
-
Paneni, F.; Costantino, S.; Cosentino, F. Molecular mechanisms of vascular dysfunction and cardiovascular biomarkers in type 2 diabetes. Cardiovasc. Diagn. Ther., 2014, 4(4), 324-332.
-
(2014)
Cardiovasc. Diagn. Ther.
, vol.4
, Issue.4
, pp. 324-332
-
-
Paneni, F.1
Costantino, S.2
-
84
-
-
84862095921
-
Primary prevention of atherosclerosis: A clinical challenge for the reversal of epigenetic mechanisms?
-
Napoli, C.; Crudele, V.; Soricelli, A.; Al-Omran, M.; Vitale, N.; Infante, T.; Mancini, F.P. Primary prevention of atherosclerosis: a clinical challenge for the reversal of epigenetic mechanisms? Circulation, 2012, 125(19), 2363-2373.
-
(2012)
Circulation
, vol.125
, Issue.19
, pp. 2363-2373
-
-
Napoli, C.1
Crudele, V.2
Soricelli, A.3
Al-Omran, M.4
Vitale, N.5
Infante, T.6
Mancini, F.P.7
-
85
-
-
84860263532
-
Nutrition, epigenetics, and metabolic syndrome. Antioxid
-
Wang, J.; Wu, Z.; Li, D.; Li, N.; Dindot, S.V.; Satterfield, M.C.; Bazer, F.W.; Wu, G. Nutrition, epigenetics, and metabolic syndrome. Antioxid. Redox Signal., 2012, 17(2), 282-301.
-
(2012)
Redox Signal.
, vol.17
, Issue.2
, pp. 282-301
-
-
Wang, J.1
Wu, Z.2
Li, D.3
Li, N.4
Dindot, S.V.5
Satterfield, M.C.6
Bazer, F.W.7
Wu, G.8
-
86
-
-
79955627138
-
A sustained dietary change increases epigenetic variation in isogenic mice
-
Li, C.C.; Cropley, J.E.; Cowley, M.J.; Preiss, T.; Martin, D.I.; Suter, C.M. A sustained dietary change increases epigenetic variation in isogenic mice. PLoS Genet., 2011, 7(4), e1001380.
-
(2011)
Plos Genet
, vol.7
, Issue.4
-
-
Li, C.C.1
Cropley, J.E.2
Cowley, M.J.3
Preiss, T.4
Martin, D.I.5
Suter, C.M.6
-
87
-
-
84862776863
-
Zheng, L. Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets
-
Li, J.; Huang, J.; Li, J.S.; Chen, H.; Huang, K.; Zheng, L. Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets. J. Hepatol., 2012, 56(4), 900-907.
-
(2012)
J. Hepatol.
, vol.56
, Issue.4
, pp. 900-907
-
-
Li, J.1
Huang, J.2
Li, J.S.3
Chen, H.4
Huang, K.5
-
88
-
-
70350313230
-
Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice
-
Dunn, G.A.; Bale, T.L. Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice. Endocrinology, 2009, 150(11), 4999-5009.
-
(2009)
Endocrinology
, vol.150
, Issue.11
, pp. 4999-5009
-
-
Dunn, G.A.1
Bale, T.L.2
-
89
-
-
84856558597
-
Heritable transmission of diabetic metabolic memory in zebrafish correlates with DNA hypomethylation and aberrant gene expression
-
Olsen, A.S.; Sarras, M.P., Jr.; Leontovich, A.; Intine, R.V. Heritable transmission of diabetic metabolic memory in zebrafish correlates with DNA hypomethylation and aberrant gene expression. Diabetes, 2012, 61(2), 485-491.
-
(2012)
Diabetes
, vol.61
, Issue.2
, pp. 485-491
-
-
Olsen, A.S.1
Sarras, M.P.2
Leontovich, A.3
Intine, R.V.4
-
90
-
-
0020658546
-
Excessive obesity in offspring of Pima Indian women with diabetes during pregnancy
-
Pettitt, D.J.; Baird, H.R.; Aleck, K.A.; Bennett, P.H.; Knowler, W.C. Excessive obesity in offspring of Pima Indian women with diabetes during pregnancy. N. Engl. J. Med., 1983, 308(5), 242-245.
-
(1983)
N. Engl. J. Med.
, vol.308
, Issue.5
, pp. 242-245
-
-
Pettitt, D.J.1
Baird, H.R.2
Aleck, K.A.3
Bennett, P.H.4
Knowler, W.C.5
-
91
-
-
84880146957
-
Epigenetics of gestational diabetes mellitus and offspring health: The time for action is in early stages of life
-
Lehnen, H.; Zechner, U.; Haaf, T. Epigenetics of gestational diabetes mellitus and offspring health: the time for action is in early stages of life. Mol. Hum. Reprod., 2013, 19(7), 415-422.
-
(2013)
Mol. Hum. Reprod.
, vol.19
, Issue.7
, pp. 415-422
-
-
Lehnen, H.1
Zechner, U.2
Haaf, T.3
-
92
-
-
80052572090
-
Hungry in the womb: What are the consequences? Lessons from the Dutch famine
-
Roseboom, T.J.; Painter, R.C.; van Abeelen, A.F.; Veenendaal, M.V.; de Rooij, S.R. Hungry in the womb: what are the consequences? Lessons from the Dutch famine. Maturitas, 2011, 70(2), 141-145.
-
(2011)
Maturitas
, vol.70
, Issue.2
, pp. 141-145
-
-
Roseboom, T.J.1
Painter, R.C.2
Van Abeelen, A.F.3
Veenendaal, M.V.4
De Rooij, S.R.5
-
93
-
-
74549159893
-
The epigenome: Archive of the prenatal environment
-
Heijmans, B.T.; Tobi, E.W.; Lumey, L.H.; Slagboom, P.E. The epigenome: archive of the prenatal environment. Epigenetics, 2009, 4(8), 526-531.
-
(2009)
Epigenetics
, vol.4
, Issue.8
, pp. 526-531
-
-
Heijmans, B.T.1
Tobi, E.W.2
Lumey, L.H.3
Slagboom, P.E.4
-
94
-
-
45549083182
-
Prenatal nutritional deficiency and risk of adult schizophrenia
-
Brown, A.S.; Susser, E.S. Prenatal nutritional deficiency and risk of adult schizophrenia. Schizophr. Bull., 2008, 34(6), 1054-1063.
-
(2008)
Schizophr. Bull.
, vol.34
, Issue.6
, pp. 1054-1063
-
-
Brown, A.S.1
Susser, E.S.2
-
95
-
-
81055125033
-
Homocysteine promotes human endothelial cell dysfunction via site-specific epigenetic regulation of p66shc
-
Kim, C.S.; Kim, Y.R.; Naqvi, A.; Kumar, S.; Hoffman, T.A.; Jung, S.B.; Kumar, A.; Jeon, B. H.; McNamara, D.M.; Irani, K. Homocysteine promotes human endothelial cell dysfunction via site-specific epigenetic regulation of p66shc. Cardiovasc. Res., 2011, 92(3), 466-475.
-
(2011)
Cardiovasc. Res.
, vol.92
, Issue.3
, pp. 466-475
-
-
Kim, C.S.1
Kim, Y.R.2
Naqvi, A.3
Kumar, S.4
Hoffman, T.A.5
Jung, S.B.6
Kumar, A.7
Jeon, B.H.8
McNamara, D.M.9
Irani, K.10
-
96
-
-
84878107564
-
The potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation
-
Krishna, S.M.; Dear, A.; Craig, J.M.; Norman, P.E.; Golledge, J. The potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation. Atherosclerosis, 2013, 228(2), 295-305.
-
(2013)
Atherosclerosis
, vol.228
, Issue.2
, pp. 295-305
-
-
Krishna, S.M.1
Dear, A.2
Craig, J.M.3
Norman, P.E.4
Golledge, J.5
-
97
-
-
0034703084
-
Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylation
-
Yi, P.; Melnyk, S.; Pogribna, M.; Pogribny, I.P.; Hine, R.J.; James, S.J. Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylation. J. Biol. Chem., 2000, 275(38), 29318-29323.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.38
, pp. 29318-29323
-
-
Yi, P.1
Melnyk, S.2
Pogribna, M.3
Pogribny, I.P.4
Hine, R.J.5
James, S.J.6
-
98
-
-
84862111486
-
Folate and DNA methylation
-
Ly, A.; Hoyt, L.; Crowell, J.; Kim, Y.I. Folate and DNA methylation. Antioxid. Redox Signal., 2012, 17(2), 302-326.
-
(2012)
Antioxid. Redox Signal.
, vol.17
, Issue.2
, pp. 302-326
-
-
Ly, A.1
Hoyt, L.2
Crowell, J.3
Kim, Y.I.4
-
99
-
-
0031816123
-
Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women
-
Jacob, R.A.; Gretz, D.M.; Taylor, P.C.; James, S.J.; Pogribny, I.P.; Miller, B.J.; Henning, S. M.; Swendseid, M.E. Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women. J. Nutr., 1998, 128(7), 1204-1212.
-
(1998)
J. Nutr.
, vol.128
, Issue.7
, pp. 1204-1212
-
-
Jacob, R.A.1
Gretz, D.M.2
Taylor, P.C.3
James, S.J.4
Pogribny, I.P.5
Miller, B.J.6
Henning, S.M.7
Swendseid, M.E.8
-
100
-
-
79959209876
-
Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism
-
Advani, A.; Huang, Q.; Thai, K.; Advani, S.L.; White, K.E.; Kelly, D.J.; Yuen, D.A.; Connelly, K.A.; Marsden, P.A.; Gilbert, R.E. Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism. Am. J. Pathol., 2011, 178(5), 2205-2214.
-
(2011)
Am. J. Pathol.
, vol.178
, Issue.5
, pp. 2205-2214
-
-
Advani, A.1
Huang, Q.2
Thai, K.3
Advani, S.L.4
White, K.E.5
Kelly, D.J.6
Yuen, D.A.7
Connelly, K.A.8
Marsden, P.A.9
Gilbert, R.E.10
-
101
-
-
84886405768
-
The histone deacetylase inhibitor vorinostat prevents TNFalpha-induced necroptosis by regulating multiple signaling pathways
-
Wang, D.; Zhao, M.; Chen, G.; Cheng, X.; Han, X.; Lin, S.; Zhang, X.; Yu, X. The histone deacetylase inhibitor vorinostat prevents TNFalpha-induced necroptosis by regulating multiple signaling pathways. Apoptosis, 2013, 18(11), 1348-1362.
-
(2013)
Apoptosis
, vol.18
, Issue.11
, pp. 1348-1362
-
-
Wang, D.1
Zhao, M.2
Chen, G.3
Cheng, X.4
Han, X.5
Lin, S.6
Zhang, X.7
Yu, X.8
-
102
-
-
84895923936
-
Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy
-
Xie, M.; Kong, Y.; Tan, W.; May, H.; Battiprolu, P.K.; Pedrozo, Z.; Wang, Z.V.; Morales, C.; Luo, X.; Cho, G.; Jiang, N.; Jessen, M.E.; Warner, J.J.; Lavandero, S.; Gillette, T.G.; Turer, A.T.; Hill, J.A. Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy. Circulation, 2014, 129(10), 1139-1151.
-
(2014)
Circulation
, vol.129
, Issue.10
, pp. 1139-1151
-
-
Xie, M.1
Kong, Y.2
Tan, W.3
May, H.4
Battiprolu, P.K.5
Pedrozo, Z.6
Wang, Z.V.7
Morales, C.8
Luo, X.9
Cho, G.10
Jiang, N.11
Jessen, M.E.12
Warner, J.J.13
Lavandero, S.14
Gillette, T.G.15
Turer, A.T.16
Hill, J.A.17
-
103
-
-
84872066410
-
Do diabetes, metabolic syndrome or their association equally affect biventricular function? A tissue Doppler study
-
Paneni, F.; Gregori, M.; Tocci, G.; Palano, F.; Ciavarella, G.M.; Pignatelli, G.; Marra, A.; Sciarretta, S.; Ferrucci, A.; Volpe, M. Do diabetes, metabolic syndrome or their association equally affect biventricular function? A tissue Doppler study. Hypertens. Res., 2013, 36(1), 36-42.
-
(2013)
Hypertens. Res.
, vol.36
, Issue.1
, pp. 36-42
-
-
Paneni, F.1
Gregori, M.2
Tocci, G.3
Palano, F.4
Ciavarella, G.M.5
Pignatelli, G.6
Marra, A.7
Sciarretta, S.8
Ferrucci, A.9
Volpe, M.10
-
104
-
-
56549128210
-
Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure
-
Gallo, P.; Latronico, M.V.; Gallo, P.; Grimaldi, S.; Borgia, F.; Todaro, M.; Jones, P.; Gallinari, P.; De Francesco, R.; Ciliberto, G.; Steinkuhler, C.; Esposito, G.; Condorelli, G. Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure. Cardiovasc. Res., 2008, 80(3), 416-424.
-
(2008)
Cardiovasc. Res.
, vol.80
, Issue.3
, pp. 416-424
-
-
Gallo, P.1
Latronico, M.V.2
Gallo, P.3
Grimaldi, S.4
Borgia, F.5
Todaro, M.6
Jones, P.7
Gallinari, P.8
De Francesco, R.9
Ciliberto, G.10
Steinkuhler, C.11
Esposito, G.12
Condorelli, G.13
-
105
-
-
69449107940
-
Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury
-
Noh, H.; Oh, E.Y.; Seo, J.Y.; Yu, M.R.; Kim, Y.O.; Ha, H.; Lee, H.B. Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury. Am. J. Physiol. Renal Physiol., 2009, 297(3), F729-739.
-
(2009)
Am. J. Physiol. Renal Physiol.
, vol.297
, Issue.3
, pp. F729-F739
-
-
Noh, H.1
Oh, E.Y.2
Seo, J.Y.3
Yu, M.R.4
Kim, Y.O.5
Ha, H.6
Lee, H.B.7
-
106
-
-
84863349101
-
Inhibition of histone deacetylases preserves myocardial performance and prevents cardiac remodeling through stimulation of endogenous angiomyogenesis
-
Zhang, L.; Qin, X.; Zhao, Y.; Fast, L.; Zhuang, S.; Liu, P.; Cheng, G.; Zhao, T.C. Inhibition of histone deacetylases preserves myocardial performance and prevents cardiac remodeling through stimulation of endogenous angiomyogenesis. J. Pharmacol. Exp. Ther., 2012, 341(1), 285-293.
-
(2012)
J. Pharmacol. Exp. Ther.
, vol.341
, Issue.1
, pp. 285-293
-
-
Zhang, L.1
Qin, X.2
Zhao, Y.3
Fast, L.4
Zhuang, S.5
Liu, P.6
Cheng, G.7
Zhao, T.C.8
-
107
-
-
35548942629
-
Inhibition of histone deacetylases triggers pharmacologic preconditioning effects against myocardial ischemic injury
-
Zhao, T.C.; Cheng, G.; Zhang, L.X.; Tseng, Y.T.; Padbury, J.F. Inhibition of histone deacetylases triggers pharmacologic preconditioning effects against myocardial ischemic injury. Cardiovasc. Res., 2007, 76(3), 473-481.
-
(2007)
Cardiovasc. Res.
, vol.76
, Issue.3
, pp. 473-481
-
-
Zhao, T.C.1
Cheng, G.2
Zhang, L.X.3
Tseng, Y.T.4
Padbury, J.F.5
-
108
-
-
84901300519
-
Anti-inflammatory effect of sodium butyrate preconditioning during myocardial ischemia/reperfusion
-
Hu, X.; Zhang, K.; Xu, C.; Chen, Z.; Jiang, H. Anti-inflammatory effect of sodium butyrate preconditioning during myocardial ischemia/reperfusion. Exp. Ther. Med., 2014, 8(1), 229-232.
-
(2014)
Exp. Ther. Med.
, vol.8
, Issue.1
, pp. 229-232
-
-
Hu, X.1
Zhang, K.2
Xu, C.3
Chen, Z.4
Jiang, H.5
-
109
-
-
84910037370
-
Involvement of the Antioxidant effect and anti-inflammatory response in butyrate-inhibited vascular smooth muscle cell proliferation
-
Mathew, O.P.; Ranganna, K.; Milton, S.G. Involvement of the Antioxidant effect and anti-inflammatory response in butyrate-inhibited vascular smooth muscle cell proliferation. Pharmaceuticals (Basel), 2014, 7(11), 1008-1027.
-
(2014)
Pharmaceuticals (Basel)
, vol.7
, Issue.11
, pp. 1008-1027
-
-
Mathew, O.P.1
Ranganna, K.2
Milton, S.G.3
-
110
-
-
77955984513
-
HDAC inhibition attenuates inflammatory, hypertrophic, and hypertensive responses in spontaneously hypertensive rats
-
Cardinale, J.P.; Sriramula, S.; Pariaut, R.; Guggilam, A.; Mariappan, N.; Elks, C.M.; Francis, J. HDAC inhibition attenuates inflammatory, hypertrophic, and hypertensive responses in spontaneously hypertensive rats. Hypertension, 2010, 56(3), 437-444.
-
(2010)
Hypertension
, vol.56
, Issue.3
, pp. 437-444
-
-
Cardinale, J.P.1
Sriramula, S.2
Pariaut, R.3
Guggilam, A.4
Mariappan, N.5
Elks, C.M.6
Francis, J.7
-
111
-
-
84881334001
-
Potential roles of HDAC inhibitors in mitigating ischemia-induced brain damage and facilitating endogenous regeneration and recovery
-
Fessler, E.B.; Chibane, F.L.; Wang, Z.; Chuang, D.M. Potential roles of HDAC inhibitors in mitigating ischemia-induced brain damage and facilitating endogenous regeneration and recovery. Curr. Pharm. Des., 2013, 19(28), 5105-5120.
-
(2013)
Curr. Pharm. Des.
, vol.19
, Issue.28
, pp. 5105-5120
-
-
Fessler, E.B.1
Chibane, F.L.2
Wang, Z.3
Chuang, D.M.4
-
112
-
-
84876196303
-
Valproic acid attenuates ischemia-reperfusion injury in the rat brain through inhibition of oxidative stress and inflammation
-
Suda, S.; Katsura, K.; Kanamaru, T.; Saito, M.; Katayama, Y. Valproic acid attenuates ischemia-reperfusion injury in the rat brain through inhibition of oxidative stress and inflammation. Eur. J. Pharmacol., 2013, 707(1-3), 26-31.
-
(2013)
Eur. J. Pharmacol.
, vol.707
, Issue.1-3
, pp. 26-31
-
-
Suda, S.1
Katsura, K.2
Kanamaru, T.3
Saito, M.4
Katayama, Y.5
-
113
-
-
84925424159
-
Resveratrol and obesity: Can resveratrol relieve metabolic disturbances?
-
de Ligt, M.; Timmers, S.; Schrauwen, P. Resveratrol and obesity: Can resveratrol relieve metabolic disturbances? Biochim. Biophys. Acta, 2014, 10.1016/j.bbadis.2014.11.012.
-
(2014)
Biochim. Biophys. Acta
-
-
De Ligt, M.1
Timmers, S.2
Schrauwen, P.3
-
114
-
-
84860477354
-
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
-
Price, N.L.; Gomes, A.P.; Ling, A.J.; Duarte, F.V.; Martin-Montalvo, A.; North, B.J.; Agarwal, B.; Ye, L.; Ramadori, G.; Teodoro, J.S.; Hubbard, B.P.; Varela, A.T.; Davis, J. G.; Varamini, B.; Hafner, A.; Moaddel, R.; Rolo, A.P.; Coppari, R.; Palmeira, C.M.; de Cabo, R.; Baur, J. A.; Sinclair, D.A. SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function. Cell Metab., 2012, 15(5), 675-690.
-
(2012)
Cell Metab.
, vol.15
, Issue.5
, pp. 675-690
-
-
Price, N.L.1
Gomes, A.P.2
Ling, A.J.3
Duarte, F.V.4
Martin-Montalvo, A.5
North, B.J.6
Agarwal, B.7
Ye, L.8
Ramadori, G.9
Teodoro, J.S.10
Hubbard, B.P.11
Varela, A.T.12
Davis, J.G.13
Varamini, B.14
Hafner, A.15
Moaddel, R.16
Rolo, A.P.17
Coppari, R.18
Palmeira, C.M.19
De Cabo, R.20
Baur, J.A.21
Sinclair, D.A.22
more..
-
115
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha
-
Lagouge, M.; Argmann, C.; Gerhart-Hines, Z.; Meziane, H.; Lerin, C.; Daussin, F.; Messadeq, N.; Milne, J.; Lambert, P.; Elliott, P.; Geny, B.; Laakso, M.; Puigserver, P.; Auwerx, J. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell, 2006, 127(6), 1109-1122.
-
(2006)
Cell
, vol.127
, Issue.6
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
Daussin, F.6
Messadeq, N.7
Milne, J.8
Lambert, P.9
Elliott, P.10
Geny, B.11
Laakso, M.12
Puigserver, P.13
Auwerx, J.14
-
116
-
-
34548821582
-
Silencing insulin resistance through SIRT1
-
Zabolotny, J.M.; Kim, Y.B. Silencing insulin resistance through SIRT1. Cell Metab., 2007, 6(4), 247-249.
-
(2007)
Cell Metab.
, vol.6
, Issue.4
, pp. 247-249
-
-
Zabolotny, J.M.1
Kim, Y.B.2
-
117
-
-
80455143206
-
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
-
Timmers, S.; Konings, E.; Bilet, L.; Houtkooper, R.H.; van de Weijer, T.; Goossens, G.H.; Hoeks, J.; van der Krieken, S.; Ryu, D.; Kersten, S.; Moonen-Kornips, E.; Hesselink, M.K.; Kunz, I.; Schrauwen-Hinderling, V.B.; Blaak, E.E.; Auwerx, J.; Schrauwen, P. Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab., 2011, 14(5), 612-622.
-
(2011)
Cell Metab.
, vol.14
, Issue.5
, pp. 612-622
-
-
Timmers, S.1
Konings, E.2
Bilet, L.3
Houtkooper, R.H.4
Van De Weijer, T.5
Goossens, G.H.6
Hoeks, J.7
Van Der Krieken, S.8
Ryu, D.9
Kersten, S.10
Moonen-Kornips, E.11
Hesselink, M.K.12
Kunz, I.13
Schrauwen-Hinderling, V.B.14
Blaak, E.E.15
Auwerx, J.16
Schrauwen, P.17
-
118
-
-
33644878762
-
Polyphenolic compounds from red grapes acutely improve endothelial function in patients with coronary heart disease
-
Lekakis, J.; Rallidis, L.S.; Andreadou, I.; Vamvakou, G.; Kazantzoglou, G.; Magiatis, P.; Skaltsounis, A.L.; Kremastinos, D.T. Polyphenolic compounds from red grapes acutely improve endothelial function in patients with coronary heart disease. Eur. J. Cardiovasc. Prev. Rehabil., 2005, 12(6), 596-600.
-
(2005)
Eur. J. Cardiovasc. Prev. Rehabil.
, vol.12
, Issue.6
, pp. 596-600
-
-
Lekakis, J.1
Rallidis, L.S.2
Andreadou, I.3
Vamvakou, G.4
Kazantzoglou, G.5
Magiatis, P.6
Skaltsounis, A.L.7
Kremastinos, D.T.8
-
119
-
-
84950170835
-
Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure
-
Wong, R.H.; Howe, P.R.; Buckley, J.D.; Coates, A.M.; Kunz, I.; Berry, N.M. Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure. Nutr. Metab. Cardiovasc. Dis., 2011, 21(11), 851-856.
-
(2011)
Nutr. Metab. Cardiovasc. Dis.
, vol.21
, Issue.11
, pp. 851-856
-
-
Wong, R.H.1
Howe, P.R.2
Buckley, J.D.3
Coates, A.M.4
Kunz, I.5
Berry, N.M.6
-
120
-
-
77749254621
-
Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy
-
Sulaiman, M.; Matta, M.J.; Sunderesan, N.R.; Gupta, M.P.; Periasamy, M.; Gupta, M. Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy. Am. J. Physiol. Heart Circ. Physiol., 2010, 298(3), H833-843.
-
(2010)
Am. J. Physiol. Heart Circ. Physiol.
, vol.298
, Issue.3
, pp. H833-H843
-
-
Sulaiman, M.1
Matta, M.J.2
Sunderesan, N.R.3
Gupta, M.P.4
Periasamy, M.5
Gupta, M.6
-
121
-
-
77958026411
-
Resveratrol improves left ventricular diastolic relaxation in type 2 diabetes by inhibiting oxidative/nitrative stress: In vivo demonstration with magnetic resonance imaging
-
Zhang, H.; Morgan, B.; Potter, B.J.; Ma, L.; Dellsperger, K.C.; Ungvari, Z.; Zhang, C. Resveratrol improves left ventricular diastolic relaxation in type 2 diabetes by inhibiting oxidative/nitrative stress: In vivo demonstration with magnetic resonance imaging. Am. J. Physiol. Heart Circ. Physiol., 2010, 299(4), H985-994.
-
(2010)
Am. J. Physiol. Heart Circ. Physiol.
, vol.299
, Issue.4
, pp. H985-H994
-
-
Zhang, H.1
Morgan, B.2
Potter, B.J.3
Ma, L.4
Dellsperger, K.C.5
Ungvari, Z.6
Zhang, C.7
-
122
-
-
84892820006
-
Potential of resveratrol in the treatment of heart failure
-
Raj, P.; Louis, X.L.; Thandapilly, S.J.; Movahed, A.; Zieroth, S.; Netticadan, T. Potential of resveratrol in the treatment of heart failure. Life Sci., 2014, 95(2), 63-71.
-
(2014)
Life Sci.
, vol.95
, Issue.2
, pp. 63-71
-
-
Raj, P.1
Louis, X.L.2
Thandapilly, S.J.3
Movahed, A.4
Zieroth, S.5
Netticadan, T.6
-
123
-
-
84875431034
-
High-dose resveratrol supplementation in obese men: An investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition
-
Poulsen, M.M.; Vestergaard, P.F.; Clasen, B.F.; Radko, Y.; Christensen, L.P.; Stodkilde-Jorgensen, H.; Moller, N.; Jessen, N.; Pedersen, S.B.; Jorgensen, J.O. High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition. Diabetes, 2013, 62(4), 1186-1195.
-
(2013)
Diabetes
, vol.62
, Issue.4
, pp. 1186-1195
-
-
Poulsen, M.M.1
Vestergaard, P.F.2
Clasen, B.F.3
Radko, Y.4
Christensen, L.P.5
Stodkilde-Jorgensen, H.6
Moller, N.7
Jessen, N.8
Pedersen, S.B.9
Jorgensen, J.O.10
-
124
-
-
84555188488
-
Sirtuin 1-mediated cellular metabolic memory of high glucose via the LKB1/AMPK/ROS pathway and therapeutic effects of metformin
-
Zheng, Z.; Chen, H.; Li, J.; Li, T.; Zheng, B.; Zheng, Y.; Jin, H.; He, Y.; Gu, Q.; Xu, X. Sirtuin 1-mediated cellular metabolic memory of high glucose via the LKB1/AMPK/ROS pathway and therapeutic effects of metformin. Diabetes, 2012, 61(1), 217-228.
-
(2012)
Diabetes
, vol.61
, Issue.1
, pp. 217-228
-
-
Zheng, Z.1
Chen, H.2
Li, J.3
Li, T.4
Zheng, B.5
Zheng, Y.6
Jin, H.7
He, Y.8
Gu, Q.9
Xu, X.10
-
125
-
-
84891275812
-
Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1
-
Arunachalam, G.; Samuel, S.M.; Marei, I.; Ding, H.; Triggle, C.R. Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1. Br. J. Pharmacol., 2014, 171(2), 523-535.
-
(2014)
Br. J. Pharmacol.
, vol.171
, Issue.2
, pp. 523-535
-
-
Arunachalam, G.1
Samuel, S.M.2
Marei, I.3
Ding, H.4
Triggle, C.R.5
-
126
-
-
81855198988
-
The cardioprotective effects of metformin
-
El Messaoudi, S.; Rongen, G.A.; de Boer, R.A.; Riksen, N.P. The cardioprotective effects of metformin. Curr. Opin. Lipidol., 2011, 22(6), 445-453.
-
(2011)
Curr. Opin. Lipidol.
, vol.22
, Issue.6
, pp. 445-453
-
-
El Messaoudi, S.1
Rongen, G.A.2
De Boer, R.A.3
Riksen, N.P.4
-
127
-
-
84898607351
-
Effect of metformin on left ventricular function after acute myocardial infarction in patients without diabetes: The GIPS-III randomized clinical trial
-
Lexis, C.P.; van der Horst, I.C.; Lipsic, E.; Wieringa, W.G.; de Boer, R.A.; van den Heuvel, A.F.; van der Werf, H.W.; Schurer, R.A.; Pundziute, G.; Tan, E.S.; Nieuwland, W.; Willemsen, H.M.; Dorhout, B.; Molmans, B.H.; vanderHorstSchrivers, A.N.; Wolffenbuttel, B.H.; ter Horst, G.J.; van Rossum, A.C.; Tijssen, J.G.; Hillege, H.L.; de Smet, B.J.; van der Harst, P.; van Veldhuisen, D.J.; Investigators, G.I. Effect of metformin on left ventricular function after acute myocardial infarction in patients without diabetes: The GIPS-III randomized clinical trial. JAMA, 2014, 311(15), 1526-1535.
-
(2014)
JAMA
, vol.311
, Issue.15
, pp. 1526-1535
-
-
Lexis, C.P.1
Van Der Horst, I.C.2
Lipsic, E.3
Wieringa, W.G.4
De Boer, R.A.5
Van Den Heuvel, A.F.6
Van Der Werf, H.W.7
Schurer, R.A.8
Pundziute, G.9
Tan, E.S.10
Nieuwland, W.11
Willemsen, H.M.12
Dorhout, B.13
Molmans, B.H.14
Vanderhorstschrivers, A.N.15
Wolffenbuttel, B.H.16
Ter Horst, G.J.17
Van Rossum, A.C.18
Tijssen, J.G.19
Hillege, H.L.20
De Smet, B.J.21
Van Der Harst, P.22
Van Veldhuisen, D.J.23
Investigators, G.I.24
more..
-
128
-
-
67649710879
-
Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 modulate beta-cell chromatin structure
-
Kim, S.J.; Nian, C.; McIntosh, C.H. Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 modulate beta-cell chromatin structure. J. Biol. Chem., 2009, 284(19), 12896-12904.
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.19
, pp. 12896-12904
-
-
Kim, S.J.1
Nian, C.2
McIntosh, C.H.3
-
129
-
-
82255181804
-
Glucagon-like peptide 1 inhibits the sirtuin deacetylase SirT1 to stimulate pancreatic beta-cell mass expansion
-
Bastien-Dionne, P.O.; Valenti, L.; Kon, N.; Gu, W.; Buteau, J. Glucagon-like peptide 1 inhibits the sirtuin deacetylase SirT1 to stimulate pancreatic beta-cell mass expansion. Diabetes, 2011, 60(12), 3217-3222.
-
(2011)
Diabetes
, vol.60
, Issue.12
, pp. 3217-3222
-
-
Bastien-Dionne, P.O.1
Valenti, L.2
Kon, N.3
Gu, W.4
Buteau, J.5
-
130
-
-
79954618658
-
The PPAR-RXR transcriptional complex in the vasculature: Energy in the balance
-
Plutzky, J. The PPAR-RXR transcriptional complex in the vasculature: Energy in the balance. Circ. Res., 2011, 108(8), 1002-1016.
-
(2011)
Circ. Res.
, vol.108
, Issue.8
, pp. 1002-1016
-
-
Plutzky, J.1
-
131
-
-
61449133232
-
Currying the heart: Curcumin and cardioprotection
-
Srivastava, G.; Mehta, J.L. Currying the heart: curcumin and cardioprotection. J. Cardiovasc. Pharmacol. Ther., 2009, 14(1), 22-27.
-
(2009)
J. Cardiovasc. Pharmacol. Ther.
, vol.14
, Issue.1
, pp. 22-27
-
-
Srivastava, G.1
Mehta, J.L.2
-
132
-
-
80052146116
-
Natural p300-specific histone acetyltransferase inhibitor, curcumin, in addition to angiotensin-converting enzyme inhibitor, exerts beneficial effects on left ventricular systolic function after myocardial infarction in rats
-
Sunagawa, Y.; Morimoto, T.; Wada, H.; Takaya, T.; Katanasaka, Y.; Kawamura, T.; Yanagi, S.; Marui, A.; Sakata, R.; Shimatsu, A.; Kimura, T.; Kakeya, H.; Fujita, M.; Hasegawa, K. A natural p300-specific histone acetyltransferase inhibitor, curcumin, in addition to angiotensin-converting enzyme inhibitor, exerts beneficial effects on left ventricular systolic function after myocardial infarction in rats. Circ. J., 2011, 75(9), 2151-2159.
-
(2011)
Circ. J.
, vol.75
, Issue.9
, pp. 2151-2159
-
-
Sunagawa, Y.1
Morimoto, T.2
Wada, H.3
Takaya, T.4
Katanasaka, Y.5
Kawamura, T.6
Yanagi, S.7
Marui, A.8
Sakata, R.9
Shimatsu, A.10
Kimura, T.11
Kakeya, H.12
Fujita, M.13
Hasegawa, K.A.14
-
133
-
-
84865142686
-
Dietary curcumin inhibits atherosclerosis by affecting the expression of genes involved in leukocyte adhesion and transendothelial migration
-
Coban, D.; Milenkovic, D.; Chanet, A.; Khallou-Laschet, J.; Sabbe, L.; Palagani, A.; Vanden Berghe, W.; Mazur, A.; Morand, C. Dietary curcumin inhibits atherosclerosis by affecting the expression of genes involved in leukocyte adhesion and transendothelial migration. Mol. Nutr. Food Res., 2012, 56(8), 1270-1281.
-
(2012)
Mol. Nutr. Food Res.
, vol.56
, Issue.8
, pp. 1270-1281
-
-
Coban, D.1
Milenkovic, D.2
Chanet, A.3
Khallou-Laschet, J.4
Sabbe, L.5
Palagani, A.6
Vanden Berghe, W.7
Mazur, A.8
Morand, C.9
-
134
-
-
84883456347
-
Targeted delivery of curcumin for treating type 2 diabetes
-
Maradana, M.R.; Thomas, R.; O'Sullivan, B.J. Targeted delivery of curcumin for treating type 2 diabetes. Mol. Nutr. Food Res., 2013, 57(9), 1550-1556.
-
(2013)
Mol. Nutr. Food Res.
, vol.57
, Issue.9
, pp. 1550-1556
-
-
Maradana, M.R.1
Thomas, R.2
O'sullivan, B.J.3
-
135
-
-
77956058729
-
Epigenetics and cardiovascular disease
-
Ordovas, J.M.; Smith, C.E. Epigenetics and cardiovascular disease. Nat. Rev. Cardiol., 2010, 7(9), 510-519.
-
(2010)
Nat. Rev. Cardiol.
, vol.7
, Issue.9
, pp. 510-519
-
-
Ordovas, J.M.1
Smith, C.E.2
-
136
-
-
60449114341
-
Early growth response factor-1 is associated with intraluminal thrombus formation in human abdominal aortic aneurysm
-
Shin, I.S.; Kim, J.M.; Kim, K.L.; Jang, S.Y.; Jeon, E.S.; Choi, S.H.; Kim, D.K.; Suh, W.; Kim, Y.W. Early growth response factor-1 is associated with intraluminal thrombus formation in human abdominal aortic aneurysm. J. Am. Coll. Cardiol., 2009, 53(9), 792-799.
-
(2009)
J. Am. Coll. Cardiol.
, vol.53
, Issue.9
, pp. 792-799
-
-
Shin, I.S.1
Kim, J.M.2
Kim, K.L.3
Jang, S.Y.4
Jeon, E.S.5
Choi, S.H.6
Kim, D.K.7
Suh, W.8
Kim, Y.W.9
-
137
-
-
59449086815
-
Early growth response-1 regulates angiopoietin-1-induced endothelial cell proliferation, migration, and differentiation
-
Abdel-Malak, N.A.; Mofarrahi, M.; Mayaki, D.; Khachigian, L.M.; Hussain, S.N. Early growth response-1 regulates angiopoietin-1-induced endothelial cell proliferation, migration, and differentiation. Arterioscler. Thromb. Vasc. Biol., 2009, 29(2), 209-216.
-
(2009)
Arterioscler. Thromb. Vasc. Biol.
, vol.29
, Issue.2
, pp. 209-216
-
-
Abdel-Malak, N.A.1
Mofarrahi, M.2
Mayaki, D.3
Khachigian, L.M.4
Hussain, S.N.5
-
138
-
-
77649175503
-
Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription. Arterioscler
-
Wang, B.; Chen, J.; Santiago, F.S.; Janes, M.; Kavurma, M.M.; Chong, B.H.; Pimanda, J.E.; Khachigian, L.M. Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription. Arterioscler. Thromb. Vasc. Biol., 2010, 30(3), 536-545.
-
(2010)
Thromb. Vasc. Biol.
, vol.30
, Issue.3
, pp. 536-545
-
-
Wang, B.1
Chen, J.2
Santiago, F.S.3
Janes, M.4
Kavurma, M.M.5
Chong, B.H.6
Pimanda, J.E.7
Khachigian, L.M.8
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