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Volumn 7, Issue 11, 2014, Pages 1008-1027

Involvement of the antioxidant effect and anti-inflammatory response in butyrate-inhibited vascular smooth muscle cell proliferation

Author keywords

Butyrate; Glutathione peroxidase; Inflammation; NF B; Proliferation; Vascular smooth muscle cells

Indexed keywords

BUTYRIC ACID; CYCLOOXYGENASE 2; GLUTATHIONE PEROXIDASE 3; I KAPPA B ALPHA; I KAPPA B BETA; INDUCIBLE NITRIC OXIDE SYNTHASE; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; TRANSCRIPTION FACTOR RELA; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84910037370     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph7111008     Document Type: Article
Times cited : (40)

References (58)
  • 1
    • 0036851826 scopus 로고    scopus 로고
    • Vascular proliferation and atherosclerosis: New perspectives and therapeutic strategies
    • Dzau, V.J.; Braun-Dullaeus, R.C.; Sedding, D.G. Vascular proliferation and atherosclerosis: New perspectives and therapeutic strategies. Nat. Med. 2002, 8, 1249-1256.
    • (2002) Nat. Med , vol.8 , pp. 1249-1256
    • Dzau, V.J.1    Braun-Dullaeus, R.C.2    Sedding, D.G.3
  • 2
    • 0037421540 scopus 로고    scopus 로고
    • State of the art in coronary intervention
    • Holmes, D.R., Jr. State of the art in coronary intervention. Am. J. Cardiol. 2003, 91, 50A-53A.
    • (2003) Am. J. Cardiol , vol.91 , pp. 50A-53A
    • Holmes, D.R.1
  • 3
    • 4043112624 scopus 로고    scopus 로고
    • Gene- and cell-based therapies for cardiovascular diseases: Current status and future directions
    • Melo, L.G.; Gnecchi, M.; Pachori, A.S.; Wang, K.; Dzau, V.J. Gene- and cell-based therapies for cardiovascular diseases: Current status and future directions. Eur. Heart. J. Suppl. 2004, 6, E24-E35.
    • (2004) Eur. Heart. J. Suppl , vol.6 , pp. E24-E35
    • Melo, L.G.1    Gnecchi, M.2    Pachori, A.S.3    Wang, K.4    Dzau, V.J.5
  • 4
    • 33750716498 scopus 로고    scopus 로고
    • Insights into the pathogenesis and intervention of atherosclerosis
    • Ranganna, K.; Yatsu, F.M.; Mathew, O.P. Insights into the pathogenesis and intervention of atherosclerosis. Vasc. Dis. Prev. 2006, 3, 375-390.
    • (2006) Vasc. Dis. Prev , vol.3 , pp. 375-390
    • Ranganna, K.1    Yatsu, F.M.2    Mathew, O.P.3
  • 5
    • 33750698351 scopus 로고    scopus 로고
    • Butyrate, a small pleiotropic molecule with multiple cellular and molecular actions: Its role as an anti-atherogenic agent
    • Ranganna, K.; Yatsu, F.M.; Hayes, B.E. Butyrate, a small pleiotropic molecule with multiple cellular and molecular actions: Its role as an anti-atherogenic agent. Recent Res. Dev. Mol. Cell. Biochem. 2005, 2, 123-151.
    • (2005) Recent Res. Dev. Mol. Cell. Biochem. , vol.2 , pp. 123-151
    • Ranganna, K.1    Yatsu, F.M.2    Hayes, B.E.3
  • 6
    • 68349091525 scopus 로고    scopus 로고
    • Epigenetic control of gene expression
    • Ekström, T.J. Epigenetic control of gene expression. Biochim. Biophys. Acta 2009, 1790, 845-846.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 845-846
    • Ekström, T.J.1
  • 7
    • 59749094084 scopus 로고    scopus 로고
    • Epigenetic histone acetylation modifiers in vascular remodeling: New targets for therapy in cardiovascular disease
    • Pons, D.; de Vries, F.R.; van den Elsen, P.J.; Heijmans, B.T.; Quax, P.H.; Jukema, J.W. Epigenetic histone acetylation modifiers in vascular remodeling: New targets for therapy in cardiovascular disease. Eur. Heart J. 2009, 30, 266-277.
    • (2009) Eur. Heart J , vol.30 , pp. 266-277
    • Pons, D.1    de Vries, F.R.2    van den Elsen, P.J.3    Heijmans, B.T.4    Quax, P.H.5    Jukema, J.W.6
  • 9
    • 84910102995 scopus 로고    scopus 로고
    • Emerging Epigenetic Therapy for Vascular Proliferative Diseases
    • Parthasarathy, S., Ed.; InTech: Rijeka, Croatia
    • Ranganna, K.; Yatsu, F.M.; Mathew, O.P. Emerging Epigenetic Therapy for Vascular Proliferative Diseases. Atherogenesis; Parthasarathy, S., Ed.; InTech: Rijeka, Croatia, 2011.
    • (2011) Atherogenesis
    • Ranganna, K.1    Yatsu, F.M.2    Mathew, O.P.3
  • 10
    • 78649904991 scopus 로고    scopus 로고
    • Butyrate, an HDAC inhibitor, stimulates interplay between different posttranslational modifications of histone H3 and differently alters G1- specific cell cycle proteins in vascular smooth muscle cells
    • Mathew, O.P.; Ranganna, K.; Yatsu, F.M. Butyrate, an HDAC inhibitor, stimulates interplay between different posttranslational modifications of histone H3 and differently alters G1- specific cell cycle proteins in vascular smooth muscle cells. Biomed. Pharmacother. 2010, 64, 733-740.
    • (2010) Biomed. Pharmacother. , vol.64 , pp. 733-740
    • Mathew, O.P.1    Ranganna, K.2    Yatsu, F.M.3
  • 12
    • 35748982083 scopus 로고    scopus 로고
    • Involvement of glutathione/glutathione S-transferase antioxidant system in butyrate-inhibited vascular smooth muscle cell proliferation
    • Ranganna, K.; Mathew, O.P.; Yatsu, F.M.; Yousefipour, Z.; Hayes, B.E.; Milton, S.G. Involvement of glutathione/glutathione S-transferase antioxidant system in butyrate-inhibited vascular smooth muscle cell proliferation. FEBS J. 2007, 274, 5962-5978.
    • (2007) FEBS J , vol.274 , pp. 5962-5978
    • Ranganna, K.1    Mathew, O.P.2    Yatsu, F.M.3    Yousefipour, Z.4    Hayes, B.E.5    Milton, S.G.6
  • 13
    • 0344897251 scopus 로고    scopus 로고
    • Gene expression profile of butyrate-inhibited vascular smooth muscle cell proliferation
    • Ranganna, K.; Yousefipour, Z.; Yatsu, F.M.; Milton, S.G.; Hayes, B.E. Gene expression profile of butyrate-inhibited vascular smooth muscle cell proliferation. Mol. Cell. Biochem. 2003, 254, 21-36.
    • (2003) Mol. Cell. Biochem. , vol.254 , pp. 21-36
    • Ranganna, K.1    Yousefipour, Z.2    Yatsu, F.M.3    Milton, S.G.4    Hayes, B.E.5
  • 14
    • 0025171918 scopus 로고
    • Protection against free radical injury by selenoenzymes
    • Burk, R.F. Protection against free radical injury by selenoenzymes. Pharmacol. Ther. 1990, 45, 383-385.
    • (1990) Pharmacol. Ther , vol.45 , pp. 383-385
    • Burk, R.F.1
  • 15
    • 0034489653 scopus 로고    scopus 로고
    • The glutathione peroxidases
    • Arthur, J.R. The glutathione peroxidases. Cell. Mol. Life. Sci. 2000, 57, 1825-1835.
    • (2000) Cell. Mol. Life. Sci. , vol.57 , pp. 1825-1835
    • Arthur, J.R.1
  • 16
    • 33750629812 scopus 로고    scopus 로고
    • Glutathione peroxidases and redox-regulated transcription factors
    • Brigelius-Flohé, R. Glutathione peroxidases and redox-regulated transcription factors. Biol. Chem. 2006, 387, 1329-1335.
    • (2006) Biol. Chem. , vol.387 , pp. 1329-1335
    • Brigelius-Flohé, R.1
  • 19
    • 0037376674 scopus 로고    scopus 로고
    • Oxidant signals and oxidative stress
    • Finkel, T. Oxidant signals and oxidative stress. Curr. Opin. Cell Biol. 2003, 15, 247-254.
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 247-254
    • Finkel, T.1
  • 21
    • 84867916343 scopus 로고    scopus 로고
    • Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation
    • Wheeler, M.L.; Defranco, A.L. Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation. J Immunol. 2012, 189, 4405-4416.
    • (2012) J Immunol. , vol.189 , pp. 4405-4416
    • Wheeler, M.L.1    Defranco, A.L.2
  • 22
    • 18044377400 scopus 로고    scopus 로고
    • Adenosine-dependent induction of glutathione peroxidase 1 in human primary endothelial cells and protection against oxidative stress
    • Zhang, Y.; Handy, D.E.; Loscalzo, J. Adenosine-dependent induction of glutathione peroxidase 1 in human primary endothelial cells and protection against oxidative stress. Circ. Res. 2005, 96, 831-837.
    • (2005) Circ. Res. , vol.96 , pp. 831-837
    • Zhang, Y.1    Handy, D.E.2    Loscalzo, J.3
  • 23
    • 0035940411 scopus 로고    scopus 로고
    • Overexpression of cellular glutathione peroxidase rescues homocyst(e)ine-induced endothelial dysfunction
    • Weiss, N.; Zhang, Y.Y.; Heydrick, S.; Bierl, C.; Loscalzo, J. Overexpression of cellular glutathione peroxidase rescues homocyst(e)ine-induced endothelial dysfunction. Proc. Natl. Acad. Sci. USA 2001, 98, 12503-12508.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 12503-12508
    • Weiss, N.1    Zhang, Y.Y.2    Heydrick, S.3    Bierl, C.4    Loscalzo, J.5
  • 24
    • 0141642104 scopus 로고    scopus 로고
    • Glutathione peroxidase overexpression inhibits cytochrome C release and proapoptotic mediators to protect neurons from experimental stroke
    • Hoehn, B.; Yenari, M.A.; Sapolsky, R.M.; Steinberg, G.K. Glutathione peroxidase overexpression inhibits cytochrome C release and proapoptotic mediators to protect neurons from experimental stroke. Stroke 2003, 34, 2489-2494.
    • (2003) Stroke , vol.34 , pp. 2489-2494
    • Hoehn, B.1    Yenari, M.A.2    Sapolsky, R.M.3    Steinberg, G.K.4
  • 26
    • 33745779644 scopus 로고    scopus 로고
    • Glutathione peroxidase 4 protects cortical neurons from oxidative injury and amyloid toxicity
    • Ran, Q.; Gu, M.; Van Remmen, H.; Strong, R.; Roberts, J.L.; Richardson, A. Glutathione peroxidase 4 protects cortical neurons from oxidative injury and amyloid toxicity. J. Neurosci. Res. 2006, 84, 202-208.
    • (2006) J. Neurosci. Res. , vol.84 , pp. 202-208
    • Ran, Q.1    Gu, M.2    Van Remmen, H.3    Strong, R.4    Roberts, J.L.5    Richardson, A.6
  • 27
    • 8544263882 scopus 로고    scopus 로고
    • Overexpression of phospholipid-hydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation-induced expression of interstitial collagenase/matrix metalloproteinase-1 by suppression of phosphatidylcholine hydroperoxide-mediated NFkappaB activation and interleukin-6 release
    • Wenk, J.; Schüller, J.; Hinrichs, C.; Syrovets, T.; Azoitei, N.; Podda, M.; Wlaschek, M.; Brenneisen, P.; Schneider, L.A.; Sabiwalsky, A.; et al. Overexpression of phospholipid-hydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation-induced expression of interstitial collagenase/matrix metalloproteinase-1 by suppression of phosphatidylcholine hydroperoxide-mediated NFkappaB activation and interleukin-6 release. J. Biol. Chem. 2004, 279, 45634-45642.
    • (2004) J. Biol. Chem. , vol.279 , pp. 45634-45642
    • Wenk, J.1    Schüller, J.2    Hinrichs, C.3    Syrovets, T.4    Azoitei, N.5    Podda, M.6    Wlaschek, M.7    Brenneisen, P.8    Schneider, L.A.9    Sabiwalsky, A.10
  • 28
    • 33745138558 scopus 로고    scopus 로고
    • Potential contribution of NF-kappaB in neuronal cell death in the glutathione peroxidase-1 knockout mouse in response to ischemiareperfusion injury
    • Crack, P.J.; Taylor, J.M.; Ali, U.; Mansell, A.; Hertzog, P.J. Potential contribution of NF-kappaB in neuronal cell death in the glutathione peroxidase-1 knockout mouse in response to ischemiareperfusion injury. Stroke 2006, 37, 1533-1538.
    • (2006) Stroke , vol.37 , pp. 1533-1538
    • Crack, P.J.1    Taylor, J.M.2    Ali, U.3    Mansell, A.4    Hertzog, P.J.5
  • 29
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signaling
    • Hayden, M.S.; Ghosh, S. Shared principles in NF-kappaB signaling. Cell 2008, 132, 344-362.
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 30
    • 33750435582 scopus 로고    scopus 로고
    • NF-kappaB and the immune response
    • Hayden, M.S.; West, A.P.; Ghosh, S. NF-kappaB and the immune response. Oncogene 2006, 25, 6758-6580.
    • (2006) Oncogene , vol.25
    • Hayden, M.S.1    West, A.P.2    Ghosh, S.3
  • 31
    • 33750466230 scopus 로고    scopus 로고
    • Introduction to NF-kappaB: Players, pathways, perspectives
    • Gilmore, T.D. Introduction to NF-kappaB: players, pathways, perspectives. Oncogene 2006, 25, 6680-6684.
    • (2006) Oncogene , vol.25 , pp. 6680-6684
    • Gilmore, T.D.1
  • 32
    • 1642464788 scopus 로고    scopus 로고
    • Inhibition of basal and interleukin-1-induced VCAM-1 expression by phospholipid hydroperoxide glutathione peroxidase and 15-lipoxygenase in rabbit aortic smooth muscle cells
    • Banning, A.; Schnurr, K.; Böl, G.F.; Kupper, D.; Müller-Schmehl, K.; Viita, H.; Ylä- Herttuala, S.; Brigelius-Flohé, R. Inhibition of basal and interleukin-1-induced VCAM-1 expression by phospholipid hydroperoxide glutathione peroxidase and 15-lipoxygenase in rabbit aortic smooth muscle cells. Free Radic. Biol. Med. 2004, 36, 135-144.
    • (2004) Free Radic. Biol. Med. , vol.36 , pp. 135-144
    • Banning, A.1    Schnurr, K.2    Böl, G.F.3    Kupper, D.4    Müller-Schmehl, K.5    Viita, H.6    Ylä-Herttuala, S.7    Brigelius-Flohé, R.8
  • 33
    • 0030702951 scopus 로고    scopus 로고
    • Interleukin-1-induced nuclear factor kB activation is inhibited by overexpression of phospholipid hydroperoxide glutathione peroxidase in a human endothelial cell line
    • Brigelius-Flohé, R.; Friedrichs, B.; Maurer, S.; Schultz, M.; Streicher, R. Interleukin-1-induced nuclear factor kB activation is inhibited by overexpression of phospholipid hydroperoxide glutathione peroxidase in a human endothelial cell line. Biochem. J. 1997, 328, 199-203.
    • (1997) Biochem. J , vol.328 , pp. 199-203
    • Brigelius-Flohé, R.1    Friedrichs, B.2    Maurer, S.3    Schultz, M.4    Streicher, R.5
  • 36
    • 84866539217 scopus 로고    scopus 로고
    • Differential cellular and molecular effects of butyrate and trichostatin A on vascular smooth muscle cells
    • Milton, S.G.; Mathew, O.P.; Yatsu, F.M.; Ranganna, K. Differential cellular and molecular effects of butyrate and trichostatin A on vascular smooth muscle cells. Pharmaceuticals 2012, 5, 925-943.
    • (2012) Pharmaceuticals , vol.5 , pp. 925-943
    • Milton, S.G.1    Mathew, O.P.2    Yatsu, F.M.3    Ranganna, K.4
  • 38
    • 67649211166 scopus 로고    scopus 로고
    • Senenomethionine stimulates expression of glutathione peroxidase 1 and 3 and growth of bovine mammary epithelial cell in primary culture
    • Miranda, S.G.; Wang, Y.J.; Purdie, N.G.; Osborne, V.R.; Coomber, B.L.; Cant, J.P. Senenomethionine stimulates expression of glutathione peroxidase 1 and 3 and growth of bovine mammary epithelial cell in primary culture. J. Diary Sci. 2009, 92, 2670-2683.
    • (2009) J. Diary Sci. , vol.92 , pp. 2670-2683
    • Miranda, S.G.1    Wang, Y.J.2    Purdie, N.G.3    Osborne, V.R.4    Coomber, B.L.5    Cant, J.P.6
  • 39
    • 84875763680 scopus 로고    scopus 로고
    • Targeting cellular antioxidant enzymes for targeting atherosclerotin vascular disease
    • Kang, D.H.; Kang, S.W. Targeting cellular antioxidant enzymes for targeting atherosclerotin vascular disease. Biomol. Ther. 2013, 21, 89-96.
    • (2013) Biomol. Ther , vol.21 , pp. 89-96
    • Kang, D.H.1    Kang, S.W.2
  • 40
    • 84862488588 scopus 로고    scopus 로고
    • Low serum dlutathione peroxidase activity is associated with cardiovascular mortality in individuals with low HDLc's
    • Buijsse, B.; Lee, D-H.; Steffen, L.; Erickson, R.R.; Luepker, R.V.; Jacobs, D.R., Jr.; Holtzman, J.L. Low serum dlutathione peroxidase activity is associated with cardiovascular mortality in individuals with low HDLc's. PloS ONE 2012, 7, e38901.
    • (2012) PloS ONE , vol.7
    • Buijsse, B.1    Lee, D.-H.2    Steffen, L.3    Erickson, R.R.4    Luepker, R.V.5    Jacobs, D.R.6    Holtzman, J.L.7
  • 42
    • 35348916616 scopus 로고    scopus 로고
    • Molecular biology of glutathione peroxidase 4: From genomic structure to developmental expression and neural function
    • Savaskan, N.E.; Ufer, C.; Kühn, H.; Borchert, A. Molecular biology of glutathione peroxidase 4: from genomic structure to developmental expression and neural function. Biol. Chem. 2007, 388, 1007-1017.
    • (2007) Biol. Chem. , vol.388 , pp. 1007-1017
    • Savaskan, N.E.1    Ufer, C.2    Kühn, H.3    Borchert, A.4
  • 43
    • 38149060000 scopus 로고    scopus 로고
    • Suppression of atherogenesis by overexpression of glutathione peroxidase-4 in apolipoprotein E-deficient mice
    • Guo, Z.; Ran, Q.; Roberts, L.J., 2nd.; Zhou, L.; Richardson, A.; Sharan, C.; Wu, D.; Yang, H. Suppression of atherogenesis by overexpression of glutathione peroxidase-4 in apolipoprotein E-deficient mice. Free Radic. Biol. Med. 2008, 44, 343-352.
    • (2008) Free Radic. Biol. Med. , vol.44 , pp. 343-352
    • Guo, Z.1    Ran, Q.2    Roberts, L.J.3    Zhou, L.4    Richardson, A.5    Sharan, C.6    Wu, D.7    Yang, H.8
  • 44
    • 33745822021 scopus 로고    scopus 로고
    • The role of phospholipid hydroperoxide glutathione peroxidase isoforms in murine embryogenesis
    • Borchert, A.; Wang, C.C.; Ufer, C.; Schiebel, H.; Savaskan, N.E.; Kuhn, H. The role of phospholipid hydroperoxide glutathione peroxidase isoforms in murine embryogenesis. J. Biol. Chem. 2006, 28, 19655-19664.
    • (2006) J. Biol. Chem. , vol.28 , pp. 19655-19664
    • Borchert, A.1    Wang, C.C.2    Ufer, C.3    Schiebel, H.4    Savaskan, N.E.5    Kuhn, H.6
  • 45
    • 0035176943 scopus 로고    scopus 로고
    • The oxidative modification hypothesis of atherosclerosis: Does it hold for humans?
    • Witztum, J.L.; Steinberg, D. The oxidative modification hypothesis of atherosclerosis: Does it hold for humans? Trends Cardiovasc. Med. 2001, 11, 93-102.
    • (2001) Trends Cardiovasc. Med. , vol.11 , pp. 93-102
    • Witztum, J.L.1    Steinberg, D.2
  • 46
    • 0027534090 scopus 로고
    • Smooth muscle cells and the pathogenesis of the lesions of atherosclerosis
    • Raines, E.W.; Ross, R. Smooth muscle cells and the pathogenesis of the lesions of atherosclerosis. Br. Heart J. 1993, 69, S30-S37.
    • (1993) Br. Heart J. , vol.69 , pp. S30-S37
    • Raines, E.W.1    Ross, R.2
  • 47
    • 0033821778 scopus 로고    scopus 로고
    • Overexpression of PHGPx inhibits hydroperoxide-induced oxidation, NFkappaB activation and apoptosis and affects oxLDL-mediated proliferation of rabbit aortic smooth muscle cells
    • Brigelius-Flohé, R.; Maurer, S.; Lötzer, K.; Böl, G.; Kallionpää, H.; Lehtolainen, P.; Viita, H.; Ylä-Herttuala, S. Overexpression of PHGPx inhibits hydroperoxide-induced oxidation, NFkappaB activation and apoptosis and affects oxLDL-mediated proliferation of rabbit aortic smooth muscle cells. Atherosclerosis 2000, 152, 307-316.
    • (2000) Atherosclerosis , vol.152 , pp. 307-316
    • Brigelius-Flohé, R.1    Maurer, S.2    Lötzer, K.3    Böl, G.4    Kallionpää, H.5    Lehtolainen, P.6    Viita, H.7    Ylä-Herttuala, S.8
  • 48
    • 11244270281 scopus 로고    scopus 로고
    • Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis
    • Ran, Q.; Liang, H.; Gu, M.; Qi, W.; Walter, C.A.; Roberts, L.J., 2nd.; Herman, B.; Richardson, A.; Van Remmen, H. Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis. J. Biol. Chem. 2004, 279, 55137-55146.
    • (2004) J. Biol. Chem. , vol.279 , pp. 55137-55146
    • Ran, Q.1    Liang, H.2    Gu, M.3    Qi, W.4    Walter, C.A.5    Roberts, L.J.6    Herman, B.7    Richardson, A.8    Van Remmen, H.9
  • 49
    • 84856641109 scopus 로고    scopus 로고
    • NF-κB, the first quarter-century: Remarkable progress and outstanding questions
    • Hayden, M.S.; Ghosh, S. NF-κB, the first quarter-century: Remarkable progress and outstanding questions. Genes Dev. 2012, 26, 203-234.
    • (2012) Genes Dev. , vol.26 , pp. 203-234
    • Hayden, M.S.1    Ghosh, S.2
  • 50
    • 0037851769 scopus 로고    scopus 로고
    • IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide
    • Yang, F.; Tang, E.; Guan, K.; Wang, C.Y. IKK beta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide. J. Immunol. 2003, 170, 5630-5635.
    • (2003) J. Immunol. , vol.170 , pp. 5630-5635
    • Yang, F.1    Tang, E.2    Guan, K.3    Wang, C.Y.4
  • 51
    • 39049183044 scopus 로고    scopus 로고
    • Regulation and function of IKK and IKK-related kinases
    • Häcker, H.; Karin, M. Regulation and function of IKK and IKK-related kinases. Sci. STKE 2006, 2006, re13.
    • (2006) Sci. STKE , vol.2006
    • Häcker, H.1    Karin, M.2
  • 53
    • 33750457370 scopus 로고    scopus 로고
    • Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway
    • Perkins, N.D. Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway. Oncogene. 2006, 25, 6717-6730.
    • (2006) Oncogene. , vol.25 , pp. 6717-6730
    • Perkins, N.D.1
  • 54
    • 78651445615 scopus 로고    scopus 로고
    • How natural dietary antioxidants in fruits, vegetables and legumes promote vascular health
    • Wang, S.; Melnyk, J.; Tsao, R.; Marcone, M.F. How natural dietary antioxidants in fruits, vegetables and legumes promote vascular health. Food Res. Intl. 2011, 44, 14-22.
    • (2011) Food Res. Intl , vol.44 , pp. 14-22
    • Wang, S.1    Melnyk, J.2    Tsao, R.3    Marcone, M.F.4
  • 55
    • 84862827382 scopus 로고    scopus 로고
    • ulforaphane suppresses vascular adhesion molecule-1 expression in TNF-α-stimulated mouse vascular smooth muscle cells: Involvement of the MAPK, NF-κB and AP-1 signaling pathways
    • Kim, J.Y.; Park, H.J.; Um, S.H.; Sohn, E.H.; Kim, B.O.; Moon, E.Y.; Rhee, D.K.; Pyo, S. ulforaphane suppresses vascular adhesion molecule-1 expression in TNF-α-stimulated mouse vascular smooth muscle cells: involvement of the MAPK, NF-κB and AP-1 signaling pathways. Vascul. Pharmacol. 2012, 56, 131-141.
    • (2012) Vascul. Pharmacol. , vol.56 , pp. 131-141
    • Kim, J.Y.1    Park, H.J.2    Um, S.H.3    Sohn, E.H.4    Kim, B.O.5    Moon, E.Y.6    Rhee, D.K.7    Pyo, S.8
  • 56
    • 68149145788 scopus 로고    scopus 로고
    • Molecular targets of nutraceuticals derived from dietary spices: Potential role in suppression of inflammation and tumorigenesis
    • Aggarwal, B.B.; Van Kuiken, M.E.; Iyer, L.H.; Harikumar, K.B.; Sung, B. Molecular targets of nutraceuticals derived from dietary spices: potential role in suppression of inflammation and tumorigenesis. Exp. Biol. Med. 2009, 234, 825-849.
    • (2009) Exp. Biol. Med. , vol.234 , pp. 825-849
    • Aggarwal, B.B.1    Van Kuiken, M.E.2    Iyer, L.H.3    Harikumar, K.B.4    Sung, B.5
  • 57
    • 80054980812 scopus 로고    scopus 로고
    • Regulation of inflammation by short chain fatty acids
    • Vinolo, M.A.; Rodrigues, H.G.; Nachbar, R.T.; Curi, R. Regulation of inflammation by short chain fatty acids. Nutrients 2011, 3, 858-876.
    • (2011) Nutrients , vol.3 , pp. 858-876
    • Vinolo, M.A.1    Rodrigues, H.G.2    Nachbar, R.T.3    Curi, R.4
  • 58
    • 84857833863 scopus 로고    scopus 로고
    • Butyrate attenuates lipopolysaccharide-induced inflammation in intestinal cells and Crohn's mucosa through modulation of antioxidant defense machinery
    • Russo, I.; Luciani, A.; De Cicco, P.; Troncone, E.; Ciacci, C. Butyrate attenuates lipopolysaccharide-induced inflammation in intestinal cells and Crohn's mucosa through modulation of antioxidant defense machinery. PLoS One 2012, 7, e32841.
    • (2012) PLoS One , vol.7
    • Russo, I.1    Luciani, A.2    De Cicco, P.3    Troncone, E.4    Ciacci, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.