메뉴 건너뛰기




Volumn 299, Issue 1, 2010, Pages

The role of epigenetics in the pathology of diabetic complications

Author keywords

Diabetes; Diabetic kidney disease; Hyperglycemia; Metabolic memory

Indexed keywords

DNA; MICRORNA;

EID: 77953860649     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00200.2010     Document Type: Review
Times cited : (270)

References (155)
  • 1
    • 0037093012 scopus 로고    scopus 로고
    • Effect of intensive therapy on the microvascular complications of type 1 diabetes mellitus
    • Writing Team DCCT/EDIC Research Group
    • Writing Team DCCT/EDIC Research Group. Effect of intensive therapy on the microvascular complications of type 1 diabetes mellitus. JAMA 287: 2563-2569, 2002.
    • (2002) JAMA , vol.287 , pp. 2563-2569
  • 2
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development, and progression of long-term complications in insulin-dependent diabetes mellitus
    • DCCT Research Group. The Diabetes Control and Complications Trial Research Group
    • DCCT Research Group. The effect of intensive treatment of diabetes on the development, and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med 329: 977-986, 1993.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 3
    • 49649122472 scopus 로고    scopus 로고
    • Moving AHEAD with an international human epigenome project
    • Human Epigenome Task Force
    • Human Epigenome Task Force. Moving AHEAD with an international human epigenome project. Nature 454: 711-715, 2008.
    • (2008) Nature , vol.454 , pp. 711-715
  • 4
    • 0142087597 scopus 로고    scopus 로고
    • Sustained effect of intensive treatment of type 1 diabetes mellitus on development, and progression of diabetic nephropathy: The Epidemiology of Diabetes Interventions and Complications (EDIC) study
    • EDIC Study
    • EDIC Study. Sustained effect of intensive treatment of type 1 diabetes mellitus on development, and progression of diabetic nephropathy: the Epidemiology of Diabetes Interventions and Complications (EDIC) study. JAMA 290: 2159-2167, 2003.
    • (2003) JAMA , vol.290 , pp. 2159-2167
  • 6
    • 55949117806 scopus 로고    scopus 로고
    • Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases
    • Aggarwal BB, Harikumar KB. Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases. Int J Biochem Cell Biol 41: 40-59, 2009.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 40-59
    • Aggarwal, B.B.1    Harikumar, K.B.2
  • 8
    • 0034802887 scopus 로고    scopus 로고
    • The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression
    • Ashburner BP, Westerheide SD, Baldwin AS Jr. The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Mol Cell Biol 21: 7065-7077, 2001.
    • (2001) Mol Cell Biol , vol.21 , pp. 7065-7077
    • Ashburner, B.P.1    Westerheide, S.D.2    Baldwin Jr., A.S.3
  • 12
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233, 2009.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 13
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications in diabetes
    • Baynes JW. Role of oxidative stress in development of complications in diabetes. Diabetes 40: 405-412, 1991.
    • (1991) Diabetes , vol.40 , pp. 405-412
    • Baynes, J.W.1
  • 16
    • 34249337761 scopus 로고    scopus 로고
    • Perceptions of epigenetics
    • Bird A. Perceptions of epigenetics. Nature 447: 396-398, 2007.
    • (2007) Nature , vol.447 , pp. 396-398
    • Bird, A.1
  • 17
    • 65549170303 scopus 로고    scopus 로고
    • Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail
    • Brasacchio D, Okabe J, Tikellis C, Balcerczyk A, George P, Baker EK, Calkin AC, Brownlee M, Cooper ME, El-Osta A. Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail. Diabetes 58: 1229-1236, 2009.
    • (2009) Diabetes , vol.58 , pp. 1229-1236
    • Brasacchio, D.1    Okabe, J.2    Tikellis, C.3    Balcerczyk, A.4    George, P.5    Baker, E.K.6    Calkin, A.C.7    Brownlee, M.8    Cooper, M.E.9    El-Osta, A.10
  • 19
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • DOI 10.1038/414813a
    • Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 414: 813-820, 2001. (Pubitemid 34000785)
    • (2001) Nature , vol.414 , Issue.6865 , pp. 813-820
    • Brownlee, M.1
  • 20
    • 20044376702 scopus 로고    scopus 로고
    • The pathobiology of diabetic complications: A unifying mechanism
    • DOI 10.2337/diabetes.54.6.1615
    • Brownlee M. The pathobiology of diabetic complications: a unifying mechanism. Diabetes 54: 1615-1625, 2005. (Pubitemid 40770750)
    • (2005) Diabetes , vol.54 , Issue.6 , pp. 1615-1625
    • Brownlee, M.1
  • 21
    • 0023950461 scopus 로고
    • Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications
    • Brownlee M, Cerami A, Vlassara H. Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications. N Engl J Med 318: 1315-1321, 1988.
    • (1988) N Engl J Med , vol.318 , pp. 1315-1321
    • Brownlee, M.1    Cerami, A.2    Vlassara, H.3
  • 22
    • 65449151412 scopus 로고    scopus 로고
    • Therapies for hyperglycaemia-induced diabetic complications: From animal models to clinical trials
    • Calcutt NA, Cooper ME, Kern TS, Schmidt AM. Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials. Nat Rev Drug Discov 8: 417-429, 2009.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 417-429
    • Calcutt, N.A.1    Cooper, M.E.2    Kern, T.S.3    Schmidt, A.M.4
  • 23
    • 48449098502 scopus 로고    scopus 로고
    • Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients
    • Ceriello A, Esposito K, Piconi L, Ihnat MA, Thorpe JE, Testa R, Boemi M, Giugliano D. Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients. Diabetes 57: 1349-1354, 2008.
    • (2008) Diabetes , vol.57 , pp. 1349-1354
    • Ceriello, A.1    Esposito, K.2    Piconi, L.3    Ihnat, M.A.4    Thorpe, J.E.5    Testa, R.6    Boemi, M.7    Giugliano, D.8
  • 24
    • 59749094860 scopus 로고    scopus 로고
    • Clinical review 2: The "metabolic memory": Is more than just tight glucose control necessary to prevent diabetic complications?
    • Ceriello A, Ihnat MA, Thorpe JE. Clinical review 2: the "metabolic memory": is more than just tight glucose control necessary to prevent diabetic complications? J Clin Endocrinol Metab 94: 410-415, 2009.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 410-415
    • Ceriello, A.1    Ihnat, M.A.2    Thorpe, J.E.3
  • 25
    • 0038607422 scopus 로고    scopus 로고
    • Covalent histone modifications underlie the developmental regulation of insulin gene transcription in pancreatic beta cells
    • Chakrabarti SK, Francis J, Ziesmann SM, Garmey JC, Mirmira RG. Covalent histone modifications underlie the developmental regulation of insulin gene transcription in pancreatic beta cells. J Biol Chem 278: 23617-23623, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 23617-23623
    • Chakrabarti, S.K.1    Francis, J.2    Ziesmann, S.M.3    Garmey, J.C.4    Mirmira, R.G.5
  • 26
    • 70749133081 scopus 로고    scopus 로고
    • Resistance of retinal inflammatory mediators to suppress after reinstitution of good glycemic control: Novel mechanism for metabolic memory
    • Chan PS, Kanwar M, Kowluru RA. Resistance of retinal inflammatory mediators to suppress after reinstitution of good glycemic control: novel mechanism for metabolic memory. J Diabetes Complications 24: 55-63, 2010.
    • (2010) J Diabetes Complications , vol.24 , pp. 55-63
    • Chan, P.S.1    Kanwar, M.2    Kowluru, R.A.3
  • 27
    • 65249093055 scopus 로고    scopus 로고
    • Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus
    • Chen H, Gu X, Su IH, Bottino R, Contreras JL, Tarakhovsky A, Kim SK. Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus. Genes Dev 23: 975-985, 2009.
    • (2009) Genes Dev , vol.23 , pp. 975-985
    • Chen, H.1    Gu, X.2    Su, I.H.3    Bottino, R.4    Contreras, J.L.5    Tarakhovsky, A.6    Kim, S.K.7
  • 29
    • 33845534203 scopus 로고    scopus 로고
    • The effect of intensive glycemic treatment on coronary artery calcification in type 1 diabetic participants of the diabetes control and complications trial/epidemiology of diabetes interventions and complications (DCCT/EDIC) study
    • DOI 10.2337/db06-0653
    • Cleary PA, Orchard TJ, Genuth S, Wong ND, Detrano R, Backlund JY, Zinman B, Jacobson A, Sun W, Lachin JM, Nathan DM. The effect of intensive glycemic treatment on coronary artery calcification in type 1 diabetic participants of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study. Diabetes 55: 3556-3565, 2006. (Pubitemid 44923617)
    • (2006) Diabetes , vol.55 , Issue.12 , pp. 3556-3565
    • Cleary, P.A.1    Orchard, T.J.2    Genuth, S.3    Wong, N.D.4    Detrano, R.5    Backlund, J.-Y.C.6    Zinman, B.7    Jacobson, A.8    Sun, W.9    Lachin, J.M.10    Nathan, D.M.11
  • 30
    • 33745191406 scopus 로고    scopus 로고
    • Reactive oxygen species signaling in vascular smooth muscle cells
    • DOI 10.1016/j.cardiores.2006.02.033, PII S0008636306001143
    • Clempus RE, Griendling KK. Reactive oxygen species signaling in vascular smooth muscle cells. Cardiovasc Res 71: 216-225, 2006. (Pubitemid 43913725)
    • (2006) Cardiovascular Research , vol.71 , Issue.2 , pp. 216-225
    • Clempus, R.E.1    Griendling, K.K.2
  • 31
    • 0036674992 scopus 로고    scopus 로고
    • Are lower fasting plasma glucose levels at diagnosis of type 2 diabetes associated with improved outcomes? UK prospective diabetes study 61
    • Colagiuri S, Cull CA, Holman RR. Are lower fasting plasma glucose levels at diagnosis of type 2 diabetes associated with improved outcomes? UK prospective diabetes study 61. Diabetes Care 25: 1410-1417, 2002.
    • (2002) Diabetes Care , vol.25 , pp. 1410-1417
    • Colagiuri, S.1    Cull, C.A.2    Holman, R.R.3
  • 32
    • 68349128481 scopus 로고    scopus 로고
    • Metabolic memory: Implications for diabetic vascular complications
    • Cooper ME. Metabolic memory: implications for diabetic vascular complications. Pediatr Diabetes 10: 343-346, 2009.
    • (2009) Pediatr Diabetes , vol.10 , pp. 343-346
    • Cooper, M.E.1
  • 33
    • 22144461002 scopus 로고    scopus 로고
    • MiRNAs, cancer, and stem cell division
    • DOI 10.1016/j.cell.2005.06.036, PII S0092867405006550
    • Croce CM, Calin GA. miRNAs, cancer, and stem cell division. Cell 122: 6-7, 2005. (Pubitemid 40977933)
    • (2005) Cell , vol.122 , Issue.1 , pp. 6-7
    • Croce, C.M.1    Calin, G.A.2
  • 34
    • 33644756809 scopus 로고    scopus 로고
    • Increased monocytic activity and biomarkers of inflammation in patients with type 1 diabetes
    • Devaraj S, Glaser N, Griffen S, Wang-Polagruto J, Miguelino E, Jialal I. Increased monocytic activity and biomarkers of inflammation in patients with type 1 diabetes. Diabetes 55: 774-779, 2006. (Pubitemid 43343235)
    • (2006) Diabetes , vol.55 , Issue.3 , pp. 774-779
    • Devaraj, S.1    Glaser, N.2    Griffen, S.3    Wang-Polagruto, J.4    Miguelino, E.5    Jialal, I.6
  • 35
    • 65249121864 scopus 로고    scopus 로고
    • Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation
    • Dhawan S, Tschen SI, Bhushan A. Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation. Genes Dev 23: 906-911, 2009.
    • (2009) Genes Dev , vol.23 , pp. 906-911
    • Dhawan, S.1    Tschen, S.I.2    Bhushan, A.3
  • 36
    • 70249106090 scopus 로고    scopus 로고
    • The epigenetic conductor a genomic orchestrator in chronic kidney disease complications?
    • Ekstrom TJ, Stenvinkel P. The epigenetic conductor: a genomic orchestrator in chronic kidney disease complications? J Nephrol 22: 442-449, 2009.
    • (2009) J Nephrol , vol.22 , pp. 442-449
    • Ekstrom, T.J.1    Stenvinkel, P.2
  • 37
    • 53349101264 scopus 로고    scopus 로고
    • Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia
    • El-Osta A, Brasacchio D, Yao D, Pocai A, Jones PL, Roeder RG, Cooper ME, Brownlee M. Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. J Exp Med 205: 2409-2417, 2008.
    • (2008) J Exp Med , vol.205 , pp. 2409-2417
    • El-Osta, A.1    Brasacchio, D.2    Yao, D.3    Pocai, A.4    Jones, P.L.5    Roeder, R.G.6    Cooper, M.E.7    Brownlee, M.8
  • 38
    • 0023641117 scopus 로고
    • Progression of incipient diabetic retinopathy during good glycemic control
    • Engerman RL, Kern TS. Progression of incipient diabetic retinopathy during good glycemic control. Diabetes 36: 808-812, 1987.
    • (1987) Diabetes , vol.36 , pp. 808-812
    • Engerman, R.L.1    Kern, T.S.2
  • 39
    • 8844281536 scopus 로고    scopus 로고
    • H2A.Z alters the nucleosome surface to promote HP1alpha-mediated chromatin fiber folding
    • DOI 10.1016/j.molcel.2004.10.023, PII S1097276504006495
    • Fan JY, Rangasamy D, Luger K, Tremethick DJ. H2A.Z alters the nucleosome surface to promote HP1alpha-mediated chromatin fiber folding. Mol Cell 16: 655-661, 2004. (Pubitemid 39531887)
    • (2004) Molecular Cell , vol.16 , Issue.4 , pp. 655-661
    • Fan, J.Y.1    Rangasamy, D.2    Luger, K.3    Tremethick, D.J.4
  • 41
  • 42
    • 63049138876 scopus 로고    scopus 로고
    • Polycomb proteins remain bound to chromatin and DNA during DNA replication in vitro
    • Francis NJ, Follmer NE, Simon MD, Aghia G, Butler JD. Polycomb proteins remain bound to chromatin and DNA during DNA replication in vitro. Cell 137: 110-122, 2009.
    • (2009) Cell , vol.137 , pp. 110-122
    • Francis, N.J.1    Follmer, N.E.2    Simon, M.D.3    Aghia, G.4    Butler, J.D.5
  • 43
  • 44
    • 77749264372 scopus 로고    scopus 로고
    • Renal failure increases cardiac histone H3 acetylation, dimethylation, and phosphorylation and the induction of cardiomyopathy-related genes in type 2 diabetes
    • Gaikwad AB, Sayyed SG, Lichtnekert J, Tikoo K, Anders HJ. Renal failure increases cardiac histone H3 acetylation, dimethylation, and phosphorylation and the induction of cardiomyopathy-related genes in type 2 diabetes. Am J Pathol 176: 1079-1083, 2010.
    • (2010) Am J Pathol , vol.176 , pp. 1079-1083
    • Gaikwad, A.B.1    Sayyed, S.G.2    Lichtnekert, J.3    Tikoo, K.4    Anders, H.J.5
  • 45
    • 2142653519 scopus 로고    scopus 로고
    • DNMT3B interacts with hSNF2H chromatin remodeling enzyme, HDACs 1 and 2, and components of the histone methylation system
    • Geiman TM, Sankpal UT, Robertson AK, Zhao Y, Zhao Y, Robertson KD. DNMT3B interacts with hSNF2H chromatin remodeling enzyme, HDACs 1 and 2, and components of the histone methylation system. Biochem Biophys Res Commun 318: 544-555, 2004.
    • (2004) Biochem Biophys Res Commun , vol.318 , pp. 544-555
    • Geiman, T.M.1    Sankpal, U.T.2    Robertson, A.K.3    Zhao, Y.4    Zhao, Y.5    Robertson, K.D.6
  • 48
    • 24944496184 scopus 로고    scopus 로고
    • Role of histone and transcription factor acetylation in diabetes pathogenesis
    • Gray SG, De Meyts P. Role of histone and transcription factor acetylation in diabetes pathogenesis. Diabetes Metab Res Rev 21: 416-433, 2005.
    • (2005) Diabetes Metab Res Rev , vol.21 , pp. 416-433
    • Gray, S.G.1    De Meyts, P.2
  • 49
    • 33646239638 scopus 로고    scopus 로고
    • Histone H3 variants and their potential role in indexing mammalian genomes: The "H3 barcode hypothesis"
    • Hake SB, Allis CD. Histone H3 variants and their potential role in indexing mammalian genomes: the "H3 barcode hypothesis". Proc Natl Acad Sci USA 103: 6428-6435, 2006.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6428-6435
    • Hake, S.B.1    Allis, C.D.2
  • 53
    • 0035937419 scopus 로고    scopus 로고
    • Histone acetyltransferase complexes stabilize swi/snf binding to promoter nucleosomes
    • Hassan AH, Neely KE, Workman JL. Histone acetyltransferase complexes stabilize swi/snf binding to promoter nucleosomes. Cell 104: 817-827, 2001.
    • (2001) Cell , vol.104 , pp. 817-827
    • Hassan, A.H.1    Neely, K.E.2    Workman, J.L.3
  • 54
    • 53549088061 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors
    • Haumaitre C, Lenoir O, Scharfmann R. Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors. Mol Cell Biol 28: 6373-6383, 2008.
    • (2008) Mol Cell Biol , vol.28 , pp. 6373-6383
    • Haumaitre, C.1    Lenoir, O.2    Scharfmann, R.3
  • 55
    • 77953841166 scopus 로고    scopus 로고
    • Role of microRNAs in obesity and the metabolic syndrome
    • Heneghan HM, Miller N, Kerin MJ. Role of microRNAs in obesity and the metabolic syndrome. Obes Rev, 2009.
    • (2009) Obes Rev
    • Heneghan, H.M.1    Miller, N.2    Kerin, M.J.3
  • 56
    • 2942746179 scopus 로고    scopus 로고
    • Histone variants, nucleosome assembly and epigenetic inheritance
    • Henikoff S, Furuyama T, Ahmad K. Histone variants, nucleosome assembly and epigenetic inheritance. Trends Genet 20: 320-326, 2004.
    • (2004) Trends Genet , vol.20 , pp. 320-326
    • Henikoff, S.1    Furuyama, T.2    Ahmad, K.3
  • 57
    • 55749104549 scopus 로고    scopus 로고
    • Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury
    • Ho J, Ng KH, Rosen S, Dostal A, Gregory RI, Kreidberg JA. Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury. J Am Soc Nephrol 19: 2069-2075, 2008.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 2069-2075
    • Ho, J.1    Ng, K.H.2    Rosen, S.3    Dostal, A.4    Gregory, R.I.5    Kreidberg, J.A.6
  • 60
    • 34249302408 scopus 로고    scopus 로고
    • Hypothesis: The 'metabolic memory', the new challenge of diabetes
    • Ihnat MA, Thorpe JE, Ceriello A. Hypothesis: the 'metabolic memory', the new challenge of diabetes. Diabet Med 24: 582-586, 2007.
    • (2007) Diabet Med , vol.24 , pp. 582-586
    • Ihnat, M.A.1    Thorpe, J.E.2    Ceriello, A.3
  • 62
    • 68349110863 scopus 로고    scopus 로고
    • Epigenetics in hyperhomocysteinemic states. A special focus on uremia
    • Ingrosso D, Perna AF. Epigenetics in hyperhomocysteinemic states. A special focus on uremia. Biochim Biophys Acta 1790: 892-899, 2009.
    • (2009) Biochim Biophys Acta , vol.1790 , pp. 892-899
    • Ingrosso, D.1    Perna, A.F.2
  • 63
    • 0031883161 scopus 로고    scopus 로고
    • Protein kinase C activation and its role in the development of vascular complications in diabetes mellitus
    • Ishii H, Koya D, King GL. Protein kinase C activation and its role in the development of vascular complications in diabetes mellitus. J Mol Med 76: 21-31, 1998.
    • (1998) J Mol Med , vol.76 , pp. 21-31
    • Ishii, H.1    Koya, D.2    King, G.L.3
  • 64
    • 0842308109 scopus 로고    scopus 로고
    • Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: Role of tyrosine nitration
    • Ito K, Hanazawa T, Tomita K, Barnes PJ, Adcock IM. Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration. Biochem Biophys Res Commun 315: 240-245, 2004.
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 240-245
    • Ito, K.1    Hanazawa, T.2    Tomita, K.3    Barnes, P.J.4    Adcock, I.M.5
  • 65
    • 36849073739 scopus 로고    scopus 로고
    • Hyperhomocysteinemia, DNA methylation and vascular disease
    • Jamaluddin MS, Yang X, Wang H. Hyperhomocysteinemia, DNA methylation and vascular disease. Clin Chem Lab Med 45: 1660-1666, 2007.
    • (2007) Clin Chem Lab Med , vol.45 , pp. 1660-1666
    • Jamaluddin, M.S.1    Yang, X.2    Wang, H.3
  • 66
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • Jenuwein T, Allis CD. Translating the histone code. Science 293: 1074-1080, 2001.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 68
    • 70349337337 scopus 로고    scopus 로고
    • MicroRNAs and their role in progressive kidney diseases
    • Kato M, Arce L, Natarajan R. MicroRNAs and their role in progressive kidney diseases. Clin J Am Soc Nephrol 4: 1255-1266, 2009.
    • (2009) Clin J Am Soc Nephrol , vol.4 , pp. 1255-1266
    • Kato, M.1    Arce, L.2    Natarajan, R.3
  • 70
    • 33847682663 scopus 로고    scopus 로고
    • MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors
    • Kato M, Zhang J, Wang M, Lanting L, Yuan H, Rossi J, Natarajan R. MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors. Proc Natl Acad Sci USA 104: 3432-3437, 2007.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 3432-3437
    • Kato, M.1    Zhang, J.2    Wang, M.3    Lanting, L.4    Yuan, H.5    Rossi, J.6    Natarajan, R.7
  • 71
    • 33845524077 scopus 로고    scopus 로고
    • Diabetes-induced extracellular matrix protein expression is mediated by transcription coactivator p300
    • Kaur H, Chen S, Xin X, Chiu J, Khan ZA, Chakrabarti S. Diabetes-induced extracellular matrix protein expression is mediated by transcription coactivator p300. Diabetes 55: 3104-3111, 2006.
    • (2006) Diabetes , vol.55 , pp. 3104-3111
    • Kaur, H.1    Chen, S.2    Xin, X.3    Chiu, J.4    Khan, Z.A.5    Chakrabarti, S.6
  • 75
    • 49449117005 scopus 로고    scopus 로고
    • The role of inflammatory cytokines in diabetes and its complications
    • King GL. The role of inflammatory cytokines in diabetes and its complications. J Periodontol 79: 1527-1534, 2008.
    • (2008) J Periodontol , vol.79 , pp. 1527-1534
    • King, G.L.1
  • 76
    • 11144355550 scopus 로고    scopus 로고
    • SWRred not shaken; mixing the histones
    • Korber P, Horz W. SWRred not shaken; mixing the histones. Cell 117: 5-7, 2004.
    • (2004) Cell , vol.117 , pp. 5-7
    • Korber, P.1    Horz, W.2
  • 77
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell 128: 693-705, 2007.
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 78
    • 0037342855 scopus 로고    scopus 로고
    • Effect of reinstitution of good glycemic control on retinal oxidative stress and nitrative stress in diabetic rats
    • Kowluru RA. Effect of reinstitution of good glycemic control on retinal oxidative stress and nitrative stress in diabetic rats. Diabetes 52: 818-823, 2003.
    • (2003) Diabetes , vol.52 , pp. 818-823
    • Kowluru, R.A.1
  • 79
    • 4444335298 scopus 로고    scopus 로고
    • Reversal of hyperglycemia and diabetic nephropathy: Effect of reinstitution of good metabolic control on oxidative stress in the kidney of diabetic rats
    • Kowluru RA, Abbas SN, Odenbach S. Reversal of hyperglycemia and diabetic nephropathy: effect of reinstitution of good metabolic control on oxidative stress in the kidney of diabetic rats. J Diabetes Complications 18: 282-288, 2004.
    • (2004) J Diabetes Complications , vol.18 , pp. 282-288
    • Kowluru, R.A.1    Abbas, S.N.2    Odenbach, S.3
  • 80
    • 12944302088 scopus 로고    scopus 로고
    • Re-institution of good metabolic control in diabetic rats and activation of caspase-3 and nuclear transcriptional factor (NF-kappaB) in the retina
    • Kowluru RA, Chakrabarti S, Chen S. Re-institution of good metabolic control in diabetic rats and activation of caspase-3 and nuclear transcriptional factor (NF-kappaB) in the retina. Acta Diabetol 41: 194-199, 2004.
    • (2004) Acta Diabetol , vol.41 , pp. 194-199
    • Kowluru, R.A.1    Chakrabarti, S.2    Chen, S.3
  • 81
    • 34547858127 scopus 로고    scopus 로고
    • Metabolic memory phenomenon and accumulation of peroxynitrite in retinal capillaries
    • Kowluru RA, Kanwar M, Kennedy A. Metabolic memory phenomenon and accumulation of peroxynitrite in retinal capillaries. Exp Diabetes Res 2007: 21976, 2007.
    • (2007) Exp Diabetes Res , vol.2007 , pp. 21976
    • Kowluru, R.A.1    Kanwar, M.2    Kennedy, A.3
  • 83
    • 67650474314 scopus 로고    scopus 로고
    • Transcriptional regulation through noncoding RNAs and epigenetic modifications
    • Kurokawa R, Rosenfeld MG, Glass CK. Transcriptional regulation through noncoding RNAs and epigenetic modifications. RNA Biol 6: 233-236, 2009.
    • (2009) RNA Biol , vol.6 , pp. 233-236
    • Kurokawa, R.1    Rosenfeld, M.G.2    Glass, C.K.3
  • 84
    • 17044392996 scopus 로고    scopus 로고
    • Role of protein methylation in regulation of transcription
    • Lee DY, Teyssier C, Strahl BD, Stallcup MR. Role of protein methylation in regulation of transcription. Endocr Rev 26: 147-170, 2005.
    • (2005) Endocr Rev , vol.26 , pp. 147-170
    • Lee, D.Y.1    Teyssier, C.2    Strahl, B.D.3    Stallcup, M.R.4
  • 85
    • 33750589423 scopus 로고    scopus 로고
    • Enhanced proatherogenic responses in macrophages and vascular smooth muscle cells derived from diabetic db/db mice
    • Li SL, Reddy MA, Cai Q, Meng L, Yuan H, Lanting L, Natarajan R. Enhanced proatherogenic responses in macrophages and vascular smooth muscle cells derived from diabetic db/db mice. Diabetes 55: 2611-2619, 2006.
    • (2006) Diabetes , vol.55 , pp. 2611-2619
    • Li, S.L.1    Reddy, M.A.2    Cai, Q.3    Meng, L.4    Yuan, H.5    Lanting, L.6    Natarajan, R.7
  • 86
    • 55549140173 scopus 로고    scopus 로고
    • Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-kappaB-dependent inflammatory genes. Relevance to diabetes and inflammation
    • Li Y, Reddy MA, Miao F, Shanmugam N, Yee JK, Hawkins D, Ren B, Natarajan R. Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-kappaB-dependent inflammatory genes. Relevance to diabetes and inflammation. J Biol Chem 283: 26771-26781, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 26771-26781
    • Li, Y.1    Reddy, M.A.2    Miao, F.3    Shanmugam, N.4    Yee, J.K.5    Hawkins, D.6    Ren, B.7    Natarajan, R.8
  • 87
    • 69449106304 scopus 로고    scopus 로고
    • SIRT1 and insulin resistance
    • Liang F, Kume S, Koya D. SIRT1 and insulin resistance. Nat Rev 5: 367-373, 2009.
    • (2009) Nat Rev , vol.5 , pp. 367-373
    • Liang, F.1    Kume, S.2    Koya, D.3
  • 89
    • 73249133400 scopus 로고    scopus 로고
    • Epigenetics: A molecular link between environmental factors and type 2 diabetes
    • Ling C, Groop L. Epigenetics: a molecular link between environmental factors and type 2 diabetes. Diabetes 58: 2718-2725, 2009.
    • (2009) Diabetes , vol.58 , pp. 2718-2725
    • Ling, C.1    Groop, L.2
  • 91
    • 58149345617 scopus 로고    scopus 로고
    • Immunopathogenic interaction of environmental triggers and genetic susceptibility in diabetes is epigenetics the missing link?
    • Litherland SA. Immunopathogenic interaction of environmental triggers and genetic susceptibility in diabetes: is epigenetics the missing link? Diabetes 57: 3184-3186, 2008.
    • (2008) Diabetes , vol.57 , pp. 3184-3186
    • Litherland, S.A.1
  • 92
    • 44449134663 scopus 로고    scopus 로고
    • Gene-environment interactions and epigenetic basis of human diseases
    • Liu L, Li Y, Tollefsbol TO. Gene-environment interactions and epigenetic basis of human diseases. Curr Issues Mol Biol 10: 25-36, 2008.
    • (2008) Curr Issues Mol Biol , vol.10 , pp. 25-36
    • Liu, L.1    Li, Y.2    Tollefsbol, T.O.3
  • 93
    • 1842411320 scopus 로고    scopus 로고
    • Crystal structure of the nucleosome core particle at 2.8 A resolution
    • Luger K, Mader AW, Richmond RK, Sargent DF, Richmond TJ. Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature 389: 251-260, 1997.
    • (1997) Nature , vol.389 , pp. 251-260
    • Luger, K.1    Mader, A.W.2    Richmond, R.K.3    Sargent, D.F.4    Richmond, T.J.5
  • 95
    • 0037380161 scopus 로고    scopus 로고
    • Recent advances in understanding chromatin remodeling by Swi/Snf complexes
    • Martens JA, Winston F. Recent advances in understanding chromatin remodeling by Swi/Snf complexes. Curr Opin Genet Dev 13: 136-142, 2003.
    • (2003) Curr Opin Genet Dev , vol.13 , pp. 136-142
    • Martens, J.A.1    Winston, F.2
  • 96
    • 27644589675 scopus 로고    scopus 로고
    • The diverse functions of histone lysine methylation
    • Martin C, Zhang Y. The diverse functions of histone lysine methylation. Nat Rev Mol Cell Biol 6: 838-849, 2005.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 838-849
    • Martin, C.1    Zhang, Y.2
  • 99
    • 2342423022 scopus 로고    scopus 로고
    • In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions
    • Miao F, Gonzalo IG, Lanting L, Natarajan R. In vivo chromatin remodeling events leading to inflammatory gene transcription under diabetic conditions. J Biol Chem 279: 18091-18097, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 18091-18097
    • Miao, F.1    Gonzalo, I.G.2    Lanting, L.3    Natarajan, R.4
  • 100
    • 58149345088 scopus 로고    scopus 로고
    • Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: An epigenetic study in diabetes
    • Miao F, Smith DD, Zhang L, Min A, Feng W, Natarajan R. Lymphocytes from patients with type 1 diabetes display a distinct profile of chromatin histone H3 lysine 9 dimethylation: an epigenetic study in diabetes. Diabetes 57: 3189-3198, 2008.
    • (2008) Diabetes , vol.57 , pp. 3189-3198
    • Miao, F.1    Smith, D.D.2    Zhang, L.3    Min, A.4    Feng, W.5    Natarajan, R.6
  • 101
    • 42149086543 scopus 로고    scopus 로고
    • Histone methylation patterns are cell-type specific in human monocytes and lymphocytes and well maintained at core genes
    • Miao F, Wu X, Zhang L, Riggs AD, Natarajan R. Histone methylation patterns are cell-type specific in human monocytes and lymphocytes and well maintained at core genes. J Immunol 180: 2264-2269, 2008.
    • (2008) J Immunol , vol.180 , pp. 2264-2269
    • Miao, F.1    Wu, X.2    Zhang, L.3    Riggs, A.D.4    Natarajan, R.5
  • 102
    • 34250303104 scopus 로고    scopus 로고
    • Genome-wide analysis of histone lysine methylation variations caused by diabetic conditions in human monocytes
    • Miao F, Wu X, Zhang L, Yuan YC, Riggs AD, Natarajan R. Genome-wide analysis of histone lysine methylation variations caused by diabetic conditions in human monocytes. J Biol Chem 282: 13854-13863, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 13854-13863
    • Miao, F.1    Wu, X.2    Zhang, L.3    Yuan, Y.C.4    Riggs, A.D.5    Natarajan, R.6
  • 103
  • 105
    • 65349144503 scopus 로고    scopus 로고
    • Epigenetic and microRNA-mediated regulation in diabetes
    • Muhonen P, Holthofer H. Epigenetic and microRNA-mediated regulation in diabetes. Nephrol Dial Transplant 24: 1088-1096, 2009.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 1088-1096
    • Muhonen, P.1    Holthofer, H.2
  • 106
    • 37349051445 scopus 로고    scopus 로고
    • The human insulin gene displays transcriptionally active epigenetic marks in islet-derived mesenchymal precursor cells in the absence of insulin expression
    • Mutskov V, Raaka BM, Felsenfeld G, Gershengorn MC. The human insulin gene displays transcriptionally active epigenetic marks in islet-derived mesenchymal precursor cells in the absence of insulin expression. Stem Cells 25: 3223-3233, 2007.
    • (2007) Stem Cells , vol.25 , pp. 3223-3233
    • Mutskov, V.1    Raaka, B.M.2    Felsenfeld, G.3    Gershengorn, M.C.4
  • 109
    • 44349191553 scopus 로고    scopus 로고
    • Epigenetic inheritance of cell differentiation status
    • Ng RK, Gurdon JB. Epigenetic inheritance of cell differentiation status. Cell Cycle 7: 1173-1177, 2008.
    • (2008) Cell Cycle , vol.7 , pp. 1173-1177
    • Ng, R.K.1    Gurdon, J.B.2
  • 110
    • 0036846539 scopus 로고    scopus 로고
    • Selective interaction between the chromatin-remodeling factor BRG1 and the heterochromatin-associated protein HP1alpha
    • Nielsen AL, Sanchez C, Ichinose H, Cervino M, Lerouge T, Chambon P, Losson R. Selective interaction between the chromatin-remodeling factor BRG1 and the heterochromatin-associated protein HP1alpha. EMBO J 21: 5797-5806, 2002.
    • (2002) EMBO J , vol.21 , pp. 5797-5806
    • Nielsen, A.L.1    Sanchez, C.2    Ichinose, H.3    Cervino, M.4    Lerouge, T.5    Chambon, P.6    Losson, R.7
  • 111
    • 69449107940 scopus 로고    scopus 로고
    • Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-β1-induced renal injury
    • Noh H, Oh EY, Seo JY, Yu MR, Kim YO, Ha H, Lee HB. Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-β1-induced renal injury. Am J Physiol Renal Physiol 297: F729-F739, 2009.
    • (2009) Am J Physiol Renal Physiol , vol.297
    • Noh, H.1    Oh, E.Y.2    Seo, J.Y.3    Yu, M.R.4    Kim, Y.O.5    Ha, H.6    Lee, H.B.7
  • 112
    • 45549097738 scopus 로고    scopus 로고
    • Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1
    • Park JH, Stoffers DA, Nicholls RD, Simmons RA. Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1. J Clin Invest 118: 2316-2324, 2008.
    • (2008) J Clin Invest , vol.118 , pp. 2316-2324
    • Park, J.H.1    Stoffers, D.A.2    Nicholls, R.D.3    Simmons, R.A.4
  • 114
    • 67649497933 scopus 로고    scopus 로고
    • Effects of prior intensive insulin therapy on cardiac autonomic nervous system function in type 1 diabetes mellitus: The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study (DCCT/EDIC)
    • Pop-Busui R, Low PA, Waberski BH, Martin CL, Albers JW, Feldman EL, Sommer C, Cleary PA, Lachin JM, Herman WH. Effects of prior intensive insulin therapy on cardiac autonomic nervous system function in type 1 diabetes mellitus: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study (DCCT/EDIC). Circulation 119: 2886-2893, 2009.
    • (2009) Circulation , vol.119 , pp. 2886-2893
    • Pop-Busui, R.1    Low, P.A.2    Waberski, B.H.3    Martin, C.L.4    Albers, J.W.5    Feldman, E.L.6    Sommer, C.7    Cleary, P.A.8    Lachin, J.M.9    Herman, W.H.10
  • 116
    • 35148819250 scopus 로고    scopus 로고
    • microRNAs and the regulation of glucose and lipid metabolism
    • Poy MN, Spranger M, Stoffel M. microRNAs and the regulation of glucose and lipid metabolism. Diabetes Obes Metab 9, Suppl 2: 67-73, 2007.
    • (2007) Diabetes Obes Metab , vol.9 , Issue.SUPPL. 2 , pp. 67-73
    • Poy, M.N.1    Spranger, M.2    Stoffel, M.3
  • 118
    • 48249127629 scopus 로고    scopus 로고
    • From fibrosis to sclerosis: Mechanisms of glomerulosclerosis in diabetic nephropathy
    • Qian Y, Feldman E, Pennathur S, Kretzler M, Brosius FC, 3rd. From fibrosis to sclerosis: mechanisms of glomerulosclerosis in diabetic nephropathy. Diabetes 57: 1439-1445, 2008.
    • (2008) Diabetes , vol.57 , pp. 1439-1445
    • Qian, Y.1    Feldman, E.2    Pennathur, S.3    Kretzler, M.4    Brosius III, F.C.5
  • 119
    • 33646557031 scopus 로고    scopus 로고
    • Epigenetics: Unfinished symphony
    • Qiu J. Epigenetics: unfinished symphony. Nature 441: 143-145, 2006.
    • (2006) Nature , vol.441 , pp. 143-145
    • Qiu, J.1
  • 120
    • 61549093719 scopus 로고    scopus 로고
    • Role of Src tyrosine kinase in the atherogenic effects of the 12/15-lipoxygenase pathway in vascular smooth muscle cells
    • Reddy MA, Sahar S, Villeneuve LM, Lanting L, Natarajan R. Role of Src tyrosine kinase in the atherogenic effects of the 12/15-lipoxygenase pathway in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 29: 387-393, 2009.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 387-393
    • Reddy, M.A.1    Sahar, S.2    Villeneuve, L.M.3    Lanting, L.4    Natarajan, R.5
  • 122
    • 0025067393 scopus 로고
    • Overexpression of fibronectin induced by diabetes or high glucose: Phenomenon with a memory
    • Roy S, Sala R, Cagliero E, Lorenzi M. Overexpression of fibronectin induced by diabetes or high glucose: phenomenon with a memory. Proc Natl Acad Sci USA 87: 404-408, 1990.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 404-408
    • Roy, S.1    Sala, R.2    Cagliero, E.3    Lorenzi, M.4
  • 123
    • 33846019277 scopus 로고    scopus 로고
    • Methylation of lysine 4 on histone H3: Intricacy of writing and reading a single epigenetic mark
    • Ruthenburg AJ, Allis CD, Wysocka J. Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark. Mol Cell 25: 15-30, 2007.
    • (2007) Mol Cell , vol.25 , pp. 15-30
    • Ruthenburg, A.J.1    Allis, C.D.2    Wysocka, J.3
  • 124
    • 2442691703 scopus 로고    scopus 로고
    • Temporal recruitment of transcription factors and SWI/SNF chromatin-remodeling enzymes during adipogenic induction of the peroxisome proliferator-activated receptor gamma nuclear hormone receptor
    • Salma N, Xiao H, Mueller E, Imbalzano AN. Temporal recruitment of transcription factors and SWI/SNF chromatin-remodeling enzymes during adipogenic induction of the peroxisome proliferator-activated receptor gamma nuclear hormone receptor. Mol Cell Biol 24: 4651-4663, 2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 4651-4663
    • Salma, N.1    Xiao, H.2    Mueller, E.3    Imbalzano, A.N.4
  • 125
    • 4344685735 scopus 로고    scopus 로고
    • Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly
    • Sarraf SA, Stancheva I. Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly. Mol Cell 15: 595-605, 2004.
    • (2004) Mol Cell , vol.15 , pp. 595-605
    • Sarraf, S.A.1    Stancheva, I.2
  • 126
    • 77952983571 scopus 로고    scopus 로고
    • Progressive glomerulosclerosis in type 2 diabetes is associated with renal histone H3K9 and H3K23 acetylation, H3K4 dimethylation and phosphorylation at serine 10
    • In press
    • Sayyed SG, Gaikwad AB, Lichtnekert J, Kulkarni O, Eulberg D, Klussmann S, Tikoo K, Anders HJ. Progressive glomerulosclerosis in type 2 diabetes is associated with renal histone H3K9 and H3K23 acetylation, H3K4 dimethylation and phosphorylation at serine 10. Nephrol Dial Transplant. In press.
    • Nephrol Dial Transplant
    • Sayyed, S.G.1    Gaikwad, A.B.2    Lichtnekert, J.3    Kulkarni, O.4    Eulberg, D.5    Klussmann, S.6    Tikoo, K.7    Anders, H.J.8
  • 127
    • 0028068046 scopus 로고
    • Cellular receptors for advanced glycation end products. Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions
    • Schmidt AM, Hori O, Brett J, Yan SD, Wautier JL, Stern D. Cellular receptors for advanced glycation end products. Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions. Arterioscler Thromb 14: 1521-1528, 1994.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1521-1528
    • Schmidt, A.M.1    Hori, O.2    Brett, J.3    Yan, S.D.4    Wautier, J.L.5    Stern, D.6
  • 128
    • 1442325581 scopus 로고    scopus 로고
    • Molecular mechanisms of high glucose-induced cyclooxygenase-2 expression in monocytes
    • Shanmugam N, Gaw Gonzalo IT, Natarajan R. Molecular mechanisms of high glucose-induced cyclooxygenase-2 expression in monocytes. Diabetes 53: 795-802, 2004.
    • (2004) Diabetes , vol.53 , pp. 795-802
    • Shanmugam, N.1    Gaw Gonzalo, I.T.2    Natarajan, R.3
  • 129
    • 0029076281 scopus 로고
    • Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-beta as a key mediator
    • Sharma K, Ziyadeh FN. Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-beta as a key mediator. Diabetes 44: 1139-1146, 1995.
    • (1995) Diabetes , vol.44 , pp. 1139-1146
    • Sharma, K.1    Ziyadeh, F.N.2
  • 132
    • 35349006314 scopus 로고    scopus 로고
    • Histone lysine demethylases: Emerging roles in development, physiology and disease
    • Shi Y. Histone lysine demethylases: emerging roles in development, physiology and disease. Nat Rev Genet 8: 829-833, 2007.
    • (2007) Nat Rev Genet , vol.8 , pp. 829-833
    • Shi, Y.1
  • 134
    • 33846025127 scopus 로고    scopus 로고
    • Dynamic regulation of histone lysine methylation by demethylases
    • Shi Y, Whetstine JR. Dynamic regulation of histone lysine methylation by demethylases. Mol Cell 25: 1-14, 2007.
    • (2007) Mol Cell , vol.25 , pp. 1-14
    • Shi, Y.1    Whetstine, J.R.2
  • 136
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • Strahl BD, Allis CD. The language of covalent histone modifications. Nature 403: 41-45, 2000.
    • (2000) Nature , vol.403 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 137
    • 33645460906 scopus 로고    scopus 로고
    • Diabetic nephropathy: A frontier for personalized medicine
    • Susztak K, Bottinger EP. Diabetic nephropathy: a frontier for personalized medicine. J Am Soc Nephrol 17: 361-367, 2006.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 361-367
    • Susztak, K.1    Bottinger, E.P.2
  • 138
    • 64749111074 scopus 로고    scopus 로고
    • Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
    • Tateishi K, Okada Y, Kallin EM, Zhang Y. Role of Jhdm2a in regulating metabolic gene expression and obesity resistance. Nature 458: 757-761, 2009.
    • (2009) Nature , vol.458 , pp. 757-761
    • Tateishi, K.1    Okada, Y.2    Kallin, E.M.3    Zhang, Y.4
  • 139
    • 33646486601 scopus 로고    scopus 로고
    • Histone lysine demethylases and their impact on epigenetics
    • Trojer P, Reinberg D. Histone lysine demethylases and their impact on epigenetics. Cell 125: 213-217, 2006.
    • (2006) Cell , vol.125 , pp. 213-217
    • Trojer, P.1    Reinberg, D.2
  • 140
  • 141
    • 0033527448 scopus 로고    scopus 로고
    • The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter
    • Vanden Berghe W, De Bosscher K, Boone E, Plaisance S, Haegeman G. The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter. J Biol Chem 274: 32091-32098, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 32091-32098
    • Vanden Berghe, W.1    De Bosscher, K.2    Boone, E.3    Plaisance, S.4    Haegeman, G.5
  • 143
    • 48249127225 scopus 로고    scopus 로고
    • Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes
    • Villeneuve LM, Reddy MA, Lanting LL, Wang M, Meng L, Natarajan R. Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes. Proc Natl Acad Sci USA 105: 9047-9052, 2008.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 9047-9052
    • Villeneuve, L.M.1    Reddy, M.A.2    Lanting, L.L.3    Wang, M.4    Meng, L.5    Natarajan, R.6
  • 144
    • 57349186092 scopus 로고    scopus 로고
    • MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy
    • Wang Q, Wang Y, Minto AW, Wang J, Shi Q, Li X, Quigg RJ. MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy. FASEB J 22: 4126-4135, 2008.
    • (2008) FASEB J , vol.22 , pp. 4126-4135
    • Wang, Q.1    Wang, Y.2    Minto, A.W.3    Wang, J.4    Shi, Q.5    Li, X.6    Quigg, R.J.7
  • 146
    • 49449111246 scopus 로고    scopus 로고
    • PARP activation and the alteration of vasoactive factors and extracellular matrix protein in retina and kidney in diabetes
    • Xu B, Chiu J, Feng B, Chen S, Chakrabarti S. PARP activation and the alteration of vasoactive factors and extracellular matrix protein in retina and kidney in diabetes. Diabetes Metab Res Rev 24: 404-412, 2008.
    • (2008) Diabetes Metab Res Rev , vol.24 , pp. 404-412
    • Xu, B.1    Chiu, J.2    Feng, B.3    Chen, S.4    Chakrabarti, S.5
  • 148
    • 33845976704 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal transition induced by TGF-beta1 in human renal epithelial cells
    • Yoshikawa M, Hishikawa K, Marumo T, Fujita T. Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal transition induced by TGF-beta1 in human renal epithelial cells. J Am Soc Nephrol 18: 58-65, 2007.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 58-65
    • Yoshikawa, M.1    Hishikawa, K.2    Marumo, T.3    Fujita, T.4
  • 149
    • 72449210573 scopus 로고    scopus 로고
    • Hyperhomocysteinemia promotes inflammatory monocyte generation and accelerates atherosclerosis in transgenic cystathionine beta-synthase-deficient mice
    • Zhang D, Jiang X, Fang P, Yan Y, Song J, Gupta S, Schafer AI, Durante W, Kruger WD, Yang X, Wang H. Hyperhomocysteinemia promotes inflammatory monocyte generation and accelerates atherosclerosis in transgenic cystathionine beta-synthase-deficient mice. Circulation 120: 1893-1902, 2009.
    • (2009) Circulation , vol.120 , pp. 1893-1902
    • Zhang, D.1    Jiang, X.2    Fang, P.3    Yan, Y.4    Song, J.5    Gupta, S.6    Schafer, A.I.7    Durante, W.8    Kruger, W.D.9    Yang, X.10    Wang, H.11
  • 150
    • 68949129008 scopus 로고    scopus 로고
    • Sirtuin 1 functionally and physically interacts with disruptor of telomeric silencing-1 to regulate alpha-ENaC transcription in collecting duct
    • Zhang D, Li S, Cruz P, Kone BC. Sirtuin 1 functionally and physically interacts with disruptor of telomeric silencing-1 to regulate alpha-ENaC transcription in collecting duct. J Biol Chem 284: 20917-20926, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 20917-20926
    • Zhang, D.1    Li, S.2    Cruz, P.3    Kone, B.C.4
  • 151
    • 58349113159 scopus 로고    scopus 로고
    • Epigenetics and the control of epithelial sodium channel expression in collecting duct
    • Zhang D, Yu ZY, Cruz P, Kong Q, Li S, Kone BC. Epigenetics and the control of epithelial sodium channel expression in collecting duct. Kidney Int 75: 260-267, 2009.
    • (2009) Kidney Int , vol.75 , pp. 260-267
    • Zhang, D.1    Yu, Z.Y.2    Cruz, P.3    Kong, Q.4    Li, S.5    Kone, B.C.6
  • 152
    • 33745873838 scopus 로고    scopus 로고
    • Dot1a-AF9 complex mediates histone H3 Lys-79 hypermethylation and repression of ENaCalpha in an aldosterone-sensitive manner
    • Zhang W, Xia X, Reisenauer MR, Hemenway CS, Kone BC. Dot1a-AF9 complex mediates histone H3 Lys-79 hypermethylation and repression of ENaCalpha in an aldosterone-sensitive manner. J Biol Chem 281: 18059-18068, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 18059-18068
    • Zhang, W.1    Xia, X.2    Reisenauer, M.R.3    Hemenway, C.S.4    Kone, B.C.5
  • 154
    • 0035883954 scopus 로고    scopus 로고
    • Transcription regulation by histone methylation: Interplay between different covalent modifications of the core histone tails
    • Zhang Y, Reinberg D. Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails. Genes Dev 15: 2343-2360, 2001.
    • (2001) Genes Dev , vol.15 , pp. 2343-2360
    • Zhang, Y.1    Reinberg, D.2
  • 155
    • 0037407935 scopus 로고    scopus 로고
    • Overview: Combating diabetic nephropathy
    • Ziyadeh FN, Sharma K. Overview: combating diabetic nephropathy. J Am Soc Nephrol 14: 1355-1357, 2003.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1355-1357
    • Ziyadeh, F.N.1    Sharma, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.