Phosphorylation of the translation initiation factor eIf2α at serine 51 determines the cell fate decisions of Akt in response to oxidative stress

Cell Death and Disease

Volumn 6, Issue 1, 2015, Pages

  Rajesh, K ^a   Krishnamoorthy, J ^a   Kazimierczak, U ^a,b   Tenkerian, C ^a,c   Papadakis, A I ^d   Wang, S ^a   Huang, S ^d   Koromilas, A E ^a,c  

^a MCGILL UNIVERSITY   (Canada)

^b POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^c MCGILL UNIVERSITY   (Canada)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 2ALPHA; INITIATION FACTOR 2ALPHA SUBUNIT SERINE 51; INSULIN RECEPTOR SUBSTRATE 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROTEIN KINASE B; RAPAMYCIN; SERINE; UNCLASSIFIED DRUG; ACTIVATING TRANSCRIPTION FACTOR 4; ATF4 PROTEIN, MOUSE; EIF2AK4 PROTEIN, MOUSE; INITIATION FACTOR 2; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; OXIDIZING AGENT; PERK KINASE; PHOSPHOSERINE; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL FATE; CELL FUNCTION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; ERYTHROID PRECURSOR CELL; FIBROBLAST; FIBROSARCOMA; GENE LOSS; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SURVIVAL FACTOR; UPREGULATION; ANIMAL; BIOLOGICAL MODEL; CELL LINEAGE; DEFICIENCY; DRUG EFFECTS; GENE DELETION; METABOLISM; PHOSPHORYLATION;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; CELL DEATH; CELL LINEAGE; CELL SURVIVAL; EIF-2 KINASE; ENZYME ACTIVATION; EUKARYOTIC INITIATION FACTOR-2; GENE DELETION; HUMANS; MICE; MODELS, BIOLOGICAL; MULTIPROTEIN COMPLEXES; OXIDANTS; OXIDATIVE STRESS; PHOSPHORYLATION; PHOSPHOSERINE; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84927591752     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.554     Document Type: Article

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