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Volumn 88, Issue 6, 2010, Pages 1273-1284

Neuroprotective effects of PDGF against oxidative stress and the signaling pathway involved

Author keywords

MAP kinase; Neuroprotection; Oxidative stress; PI3 K Akt kinase; Platelet derived growth factor

Indexed keywords

CASPASE 3; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROPIDIUM IODIDE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR;

EID: 77951607442     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22302     Document Type: Article
Times cited : (85)

References (49)
  • 2
    • 0028071936 scopus 로고
    • Platelet-derived growth factor receptor expression after neural grafting in a rat model of Parkinson's disease
    • Ballagi AE, Odin P, Othberg-Cederström A, Smits A, Duan WM, Lindvall O, Funa K. 1994. Platelet-derived growth factor receptor expression after neural grafting in a rat model of Parkinson's disease. Cell Transplant 3:453-460. (Pubitemid 24372205)
    • (1994) Cell Transplantation , vol.3 , Issue.6 , pp. 453-460
    • Ballagi, A.E.1    Odin, P.2    Othberg-Cederstrom, A.3    Smits, A.4    Duan, W.-M.5    Lindvall, O.6    Funa, K.7
  • 3
    • 2342565881 scopus 로고    scopus 로고
    • Advances in protein kinase B signalling: AKTion on multiple fronts
    • Brazil DP, Yang ZZ, Hemmings BA. 2004. Advances in protein kinase B signalling: AKTion on multiple fronts. Trends Biochem Sci 29:233-242.
    • (2004) Trends Biochem Sci , vol.29 , pp. 233-242
    • Brazil, D.P.1    Yang, Z.Z.2    Hemmings, B.A.3
  • 5
    • 0028862867 scopus 로고
    • PDGFs protect hippocampal neurons against energy deprivation and oxidative injury: Evidence for induction of antioxidant pathways
    • Cheng B, Mattson MP. 1995. PDGFs protect hippocampal neurons against energy deprivation and oxidative injury: evidence for induction of antioxidant pathways. J Neurosci 15:7095-7104.
    • (1995) J Neurosci , vol.15 , pp. 7095-7104
    • Cheng, B.1    Mattson, M.P.2
  • 8
    • 0032484019 scopus 로고    scopus 로고
    • CREB is a regulatory target for the protein kinase Akt/PKB
    • DOI 10.1074/jbc.273.49.32377
    • Du K, Montminy M. 1998. CREB is a regulatory target for the protein kinase Akt/PKB. J Biol Chem 273:32377-32379. (Pubitemid 28557606)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.49 , pp. 32377-32379
    • Du, K.1    Montminy, M.2
  • 10
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • Finkel T, Holbrook NJ. 2000. Oxidants, oxidative stress and the biology of ageing. Nature 408:239-247.
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 12
    • 0038394715 scopus 로고    scopus 로고
    • Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation
    • DOI 10.1038/ncb983
    • Haglund K, Sigismund S, Polo S, Szymkiewicz I, Di Fiore PP, Dikic I. 2003. Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation. Nat Cell Biol 5:461-466. (Pubitemid 36592270)
    • (2003) Nature Cell Biology , vol.5 , Issue.5 , pp. 461-466
    • Haglund, K.1    Sigismund, S.2    Polo, S.3    Szymkiewicz, I.4    Di Fiore, P.P.5    Dikic, I.6
  • 13
    • 0037090881 scopus 로고    scopus 로고
    • Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: A tool for temporally regulated gene activation/inactivation in the mouse
    • DOI 10.1006/dbio.2002.0597
    • Hayashi S, McMahon AP. 2002. Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: A tool for temporally regulated gene activation/inactivation in the mouse. Dev Biol 244:305-318. (Pubitemid 34450645)
    • (2002) Developmental Biology , vol.244 , Issue.2 , pp. 305-318
    • Hayashi, S.1    McMahon, A.P.2
  • 14
    • 0032875460 scopus 로고    scopus 로고
    • Mechanism of action and in vivo role of platelet-derived growth factor
    • Heldin CH, Westermark B. 1999. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev 79:1283-1316. (Pubitemid 29473317)
    • (1999) Physiological Reviews , vol.79 , Issue.4 , pp. 1283-1316
    • Heldin, C.-H.1    Westermark, B.2
  • 20
    • 33750509827 scopus 로고    scopus 로고
    • Loss of T-cell protein tyrosine phosphatase induces recycling of the platelet-derived growth factor (PDGF) β-receptor but not the PDGF α-receptor
    • DOI 10.1091/mbc.E06-04-0306
    • Karlsson S, Kowanetz K, Sandin A, Persson C, Östman A, Heldin CH, Hellberg C. 2006. Loss of t-cell protein tyrosine phosphatase induces recycling of the Platelet-Derived Growth Factor (PDGF) β-receptor but not the PDGF α-receptor. Mol Biol Cell 17:4846-4855. (Pubitemid 44665753)
    • (2006) Molecular Biology of the Cell , vol.17 , Issue.11 , pp. 4846-4855
    • Karlsson, S.1    Kowanetz, K.2    Sandin, A.3    Persson, C.4    Ostman, A.5    Heldin, C.-H.6    Hellberg, C.7
  • 21
    • 33845999302 scopus 로고    scopus 로고
    • Alix facilitates the interaction between c-Cbl and platelet-derived growth factor β-receptor and thereby modulates receptor down-regulation
    • DOI 10.1074/jbc.M608489200
    • Lennartsson J, Wardega P, Engström U, Hellman U, Heldin CH. 2006. Alix facilitates the interaction between c-Cbl and platelet-derived growth factor β-receptor and thereby modulates receptor down-regulation. J Biol Chem 281:39152-39158. (Pubitemid 46041875)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.51 , pp. 39152-39158
    • Lennartsson, J.1    Wardega, P.2    Engstrom, U.3    Hellman, U.4    Heldin, C.-H.5
  • 22
    • 0033032444 scopus 로고    scopus 로고
    • Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation
    • Matsura T, Kai M, Fujii Y, Ito H, Yamada K. 1999. Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation. Free Radic Res 30:73-83. (Pubitemid 29129415)
    • (1999) Free Radical Research , vol.30 , Issue.1 , pp. 73-83
    • Matsura, T.1    Kai, M.2    Fujii, Y.3    Ito, H.4    Yamada, K.5
  • 23
    • 0024678458 scopus 로고
    • Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress
    • Murphy TH, Miyamoto M, Sastre A, Schnaar RL, Coyle JT. 1989. Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron 2:1547-1558.
    • (1989) Neuron , vol.2 , pp. 1547-1558
    • Murphy, T.H.1    Miyamoto, M.2    Sastre, A.3    Schnaar, R.L.4    Coyle, J.T.5
  • 24
    • 33646077406 scopus 로고    scopus 로고
    • Vitamin e protected cultured cortical neurons from oxidative stress-induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase
    • Numakawa Y, Numakawa T, Matsumoto T, Yagasaki Y, Kumamaru E, Kunugi H, Taguchi T, Niki E. 2006. Vitamin E protected cultured cortical neurons from oxidative stress-induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. J Neurochem 97:1191-1202.
    • (2006) J Neurochem , vol.97 , pp. 1191-1202
    • Numakawa, Y.1    Numakawa, T.2    Matsumoto, T.3    Yagasaki, Y.4    Kumamaru, E.5    Kunugi, H.6    Taguchi, T.7    Niki, E.8
  • 27
    • 0030062706 scopus 로고    scopus 로고
    • Protective effect of platelet-derived growth factor against 6-hydroxydopamine-induced lesion of rat dopaminergic neurons in culture
    • DOI 10.1016/0304-3940(96)12326-0
    • Pietz K, Odin P, Funa K, Lindvall O. 1996. Protective effect of platelet-derived growth factor against 6-hydroxydopamine-induced lesion of rat dopaminergic neurons in culture. Neurosci Lett 204:101-104. (Pubitemid 26054456)
    • (1996) Neuroscience Letters , vol.204 , Issue.1-2 , pp. 101-104
    • Pietza, K.1    Odin, P.2    Funa, K.3    Lindvall, O.4
  • 28
    • 28044473866 scopus 로고    scopus 로고
    • Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family
    • Reigstad LJ, Varhaug JE, Lillehaug JR. 2005. Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family. FEBS J 272:5723-5741.
    • (2005) FEBS J , vol.272 , pp. 5723-5741
    • Reigstad, L.J.1    Varhaug, J.E.2    Lillehaug, J.R.3
  • 29
    • 0001952829 scopus 로고    scopus 로고
    • Redox signaling: Hydrogen peroxide as intracellular messenger
    • Rhee SG. 1999. Redox signaling: hydrogen peroxide as intracellular messenger. Exp Mol Med 31:53-59. (Pubitemid 29326708)
    • (1999) Experimental and Molecular Medicine , vol.31 , Issue.2 , pp. 53-59
    • Rhee, S.G.1
  • 30
    • 41149134840 scopus 로고    scopus 로고
    • GSK-3beta down-regulates the transcription factor Nrf2 after oxidant damage: Relevance to exposure of neuronal cells to oxidative stress
    • DOI 10.1111/j.1471-4159.2007.05124.x
    • Rojo AI, Sagarra MR, Cuadrado A. 2008. GSK-3beta down-regulates the transcription factor Nrf2 after oxidant damage: relevance to exposure of neuronal cells to oxidative stress. J Neurochem 105:192-202. (Pubitemid 351441636)
    • (2008) Journal of Neurochemistry , vol.105 , Issue.1 , pp. 192-202
    • Rojo, A.I.1    Sagarra, M.R.D.2    Cuadrado, A.3
  • 32
    • 84907036679 scopus 로고
    • Is apoptosis mediated by reactive oxygen species?
    • Sarafian TA, Bredesen DE. 1994. Is apoptosis mediated by reactive oxygen species? Free Radic Res 21:1-8.
    • (1994) Free Radic Res , vol.21 , pp. 1-8
    • Sarafian, T.A.1    Bredesen, D.E.2
  • 35
    • 0029761008 scopus 로고    scopus 로고
    • Free radical-independent protection by nerve growth factor and Bcl-2 of PC12 cells from hydrogen peroxide-triggered apoptosis
    • Satoh T, Sakai N, Enokido Y, Uchiyama Y, Hatanaka H. 1996. Free radical-independent protection by nerve growth factor and Bcl-2 of PC12 cells from hydrogen peroxide-triggered apoptosis. J Biochem 120:540-546. (Pubitemid 26331643)
    • (1996) Journal of Biochemistry , vol.120 , Issue.3 , pp. 540-546
    • Satoh, T.1    Sakai, N.2    Enokido, Y.3    Uchiyama, Y.4    Hatanaka, H.5
  • 36
    • 34547663611 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3-kinase/protein kinase B pathway by a vanadyl compound mediates its neuroprotective effect in mouse brain ischemia
    • DOI 10.1016/j.neuroscience.2007.05.040, PII S0306452207006707
    • Shioda N, Ishigami T, Han F, Moriguchi S, Shibuya M, Iwabuchi Y, Fukunaga K. 2007. Activation of phosphatidylinositol 3-kinase/protein kinase B pathway by a vanadyl compound mediates its neuroprotective effect in mouse brain ischemia. Neuroscience 148:221-229. (Pubitemid 47211622)
    • (2007) Neuroscience , vol.148 , Issue.1 , pp. 221-229
    • Shioda, N.1    Ishigami, T.2    Han, F.3    Moriguchi, S.4    Shibuya, M.5    Iwabuchi, Y.6    Fukunaga, K.7
  • 37
    • 0035937513 scopus 로고    scopus 로고
    • In vivo PDGF beta receptor activation in the dorsocaudal brain-stem of the rat prevents hypoxia-induced apoptosis via activation of Akt and BAD
    • Simakajornboon N, Szerlip NJ, Gozal E, Anonetapipat JW, Gozal D. 2001. In vivo PDGF beta receptor activation in the dorsocaudal brain-stem of the rat prevents hypoxia-induced apoptosis via activation of Akt and BAD. Brain Res 895:111-118.
    • (2001) Brain Res , vol.895 , pp. 111-118
    • Simakajornboon, N.1    Szerlip, N.J.2    Gozal, E.3    Anonetapipat, J.W.4    Gozal, D.5
  • 38
    • 0031909492 scopus 로고    scopus 로고
    • Expression of platelet-derived growth factor after intrastriatal ibotenic acid injury
    • DOI 10.1007/s002210050338
    • Sjöborg M, Pietz K, Ahgren A, Yamada N, Lindvall O, Funa K, Odin P. 1998. Expression of platelet-derived growth factor after intrastriatal ibotenic acid injury. Exp Brain Res 119:245-250. (Pubitemid 28098517)
    • (1998) Experimental Brain Research , vol.119 , Issue.2 , pp. 245-250
    • Sjoborg, M.1    Pietz, K.2    Ahgren, A.3    Yamada, N.4    Lindvall, O.5    Funa, K.6    Odin, P.7
  • 44
    • 17444372418 scopus 로고    scopus 로고
    • Platelet-derived growth factor-BB pretreatment attenuates excitotoxic death in cultured hippocampal neurons
    • Tseng HC, Dichter MA. 2005. Platelet-derived growth factor-BB pretreatment attenuates excitotoxic death in cultured hippocampal neurons. Neurobiol Dis 19:77-83.
    • (2005) Neurobiol Dis , vol.19 , pp. 77-83
    • Tseng, H.C.1    Dichter, M.A.2
  • 46
    • 47249083512 scopus 로고    scopus 로고
    • Differential modulation of Akt/ GSK-3β pathway regulates apoptotic and cytoprotective signaling responses
    • Venugopalan DN, Olanow CW. 2008. Differential modulation of Akt/ GSK-3β pathway regulates apoptotic and cytoprotective signaling responses. J Biol Chem 283:15469-15478.
    • (2008) J Biol Chem , vol.283 , pp. 15469-15478
    • Venugopalan, D.N.1    Olanow, C.W.2
  • 47
    • 57049093954 scopus 로고    scopus 로고
    • Comprehensive dissection of PDGF-PDGFR signaling pathways in PDGFR genetically defined cells
    • DOI 10.1371/journal.pone.0003794
    • Wu E, Palmer N, Tian Z, Moseman AP, Galdzicki M, Wang X, Berger B, Zhang H, Kohane IS. 2008. Comprehensive dissection of PDGF-PDGFR signaling pathways in PDGFR genetically defined cells. PLoS One 3:e3794. (Pubitemid 352761159)
    • (2008) PLoS ONE , vol.3 , Issue.11
    • Wu, E.1    Palmer, N.2    Tian, Z.3    Moseman, A.P.4    Galdzicki, M.5    Wang, X.6    Berger, B.7    Zhang, H.8    Kohane, I.S.9
  • 48
    • 0026012736 scopus 로고
    • PDGF A-chain gene is expressed by mammalian neurons during development and in maturity
    • Yeh HJ, Ruit KG, Wang YX, Parks WC, Snider WD, Deuel TF. 1991. PDGF A-chain gene is expressed by mammalian neurons during development and in maturity. Cell 64:209-216.
    • (1991) Cell , vol.64 , pp. 209-216
    • Yeh, H.J.1    Ruit, K.G.2    Wang, Y.X.3    Parks, W.C.4    Snider, W.D.5    Deuel, T.F.6
  • 49
    • 0141818115 scopus 로고    scopus 로고
    • Hypoxia induces an autocrine-paracrine survival pathway via platelet-derived growth factor (PDGF)-B/PDGF-β receptor/ phosphatidylinositol 3-kinase/Akt signaling in RN46A neuronal cells
    • Zhang SX, Gozal D, Sachleben LR Jr, Rane M, Klein JB, Gozal E. 2003. Hypoxia induces an autocrine-paracrine survival pathway via platelet-derived growth factor (PDGF)-B/PDGF-β receptor/phosphatidylinositol 3-kinase/Akt signaling in RN46A neuronal cells. FASEB J 17:1709-1711.
    • (2003) FASEB J , vol.17 , pp. 1709-1711
    • Zhang, S.X.1    Gozal, D.2    Sachleben Jr., L.R.3    Rane, M.4    Klein, J.B.5    Gozal, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.