Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2

PLoS Genetics

Volumn 8, Issue 6, 2012, Pages

  Baker, Brooke M ^a   Nargund, Amrita M ^a   Sun, Tiffany ^a   Haynes, Cole M ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR ASSOCIATED WITH STRESS 1 PROTEIN; CHAPERONE; INITIATION FACTOR 2ALPHA; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GCN2; UNCLASSIFIED DRUG; ABC TRANSPORTER; ATFS 1 PROTEIN, C ELEGANS; ATFS-1 PROTEIN, C ELEGANS; CAENORHABDITIS ELEGANS PROTEIN; HAF 1 PROTEIN, C ELEGANS; HAF-1 PROTEIN, C ELEGANS; PROTEIN KINASE R;

ARTICLE; CAENORHABDITIS ELEGANS; CELL PROTECTION; CELL STRESS; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; INTRACELLULAR SIGNALING; LIFE EXTENSION; MITOCHONDRION; NONHUMAN; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; TRANSLATION REGULATION; ANIMAL; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGICAL STRESS; PHYSIOLOGY; PROTEIN FOLDING; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

ANIMALIA; CAENORHABDITIS ELEGANS;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; EIF-2 KINASE; MITOCHONDRIA; MOLECULAR CHAPERONES; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTEIN FOLDING; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS; UNFOLDED PROTEIN RESPONSE;

EID: 84864065342     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002760     Document Type: Article

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