Pivotal role of Akt activation in mitochondrial protection and cell survival by poly(ADP-ribose)polymerase-1 inhibition in oxidative stress

Journal of Biological Chemistry

Volumn 280, Issue 42, 2005, Pages 35767-35775

  Tapodi, Antal ^a   Debreceni, Balazs ^a   Hanto, Katalin ^a   Bognar, Zita ^a   Wittmann, Istvan ^a   Gallyas Jr , Ferenc ^a   Varbiro, Gabor ^a   Sumegi, Balazs ^a  

^a UNIVERSITY OF PÉCS   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DNA; ENZYME INHIBITION; ENZYMES; OXIDATION; RNA;

AKT ACTIVATION; MITOCHONDRIAL MEMBRANES; OXIDATIVE STRESS; PI3-KINASE INHIBITORS;

ACTIVATION ANALYSIS;

2 MORPHOLINO 8 PHENYLCHROMONE; ADENOSINE TRIPHOSPHATE; HYDROGEN PEROXIDE; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; SINGLE STRANDED DNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WORTMANNIN;

ARTICLE; CATALYSIS; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DNA STRAND BREAKAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; INFLAMMATION; MEMBRANE POTENTIAL; MICROSCOPY; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NECROSIS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACETYLCYSTEINE; BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; HYDROGEN PEROXIDE; LIVER; MEMBRANE POTENTIALS; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; MODELS, BIOLOGICAL; NECROSIS; OXIDATIVE STRESS; PHOSPHORYLATION; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; TIME FACTORS;

EID: 27444446861     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M507075200     Document Type: Article

References (59)

1. Xia, Y., Khatchikian, G., and Zweier, J. L. (1996) J. Biol. Chem. 271, 10096-10102
2. Turners, J. F., and Bovanis, A. (1980) Biochem. J. 156, 434-444
3. Rowe, G. T., Manson, N. H., Caplan, M., and Hess, M. L. (1983) Circ. Res. 53, 584-591
4. Batandier, C., Leverve, X., and Fontaine, E. (2004) J. Biol. Chem. 279, 17197-17204
5. Lu, S., Nishimura, K., Hossain, M. A., Jisaka, M., Nagaya, T., and Yokota, K. (2004) Appl. Biochem. Biotechnol. 118, 133-153
6. McCord, J. M. (1987) Fed. Proc. 46, 2402-2406
7. Werner, E. (2004) J. Cell Sci. 117, 143-153
8. Martin, D., Saunas, M., Fujita, N., Tsuruo, T., and Cuadrado, A. (2002) J. Biol. Chem. 277, 42943-42952
9. D'Amours, D., Desnoyers, S., D'Silva, I., and Poirier, G. G. (1999) Biochem. J. 342, 249-268
10. de Murcia, G., and Menissier de Murcia, J. (1994) Trends Biochem. Sci. 19, 172-176
11. Althaus, F. R., Kleczkowska, H. E., Malanga, M., Muntener, C. R., Pleschke, J. M., Ebner, M., and Auer, B. (1999) Mol. Cell. Biochem. 193, 5-11
12. Berger, N. A. (1985) Radiat. Res. 101, 4-15
13. Jagtap, P., and Szabo, C. (2005) Nat. Rev. Drug Discov. 4, 421-440
14. Oleinick, N. L., and Evans, H. H. (1985) Radiat. Res. 101, 29-46
15. Ha, H. C., and Snyder, S. H. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 13978-13982
16. Zingarelli, B., Salzman, A. L., and Szabo, C. (1998) Circ. Res. 83, 85-94
17. Eliasson, M. J., Sampei, K., Mandir, A. S., Hum, P. D., Traystman, R. J., Bao, J., Pieper, A., Wang, Z. Q., Dawson, T. M., Snyder, S. H., and Dawson, V. L. (1997) Nat. Med. 3, 1089-1095
18. Endres, M., Wang, Z. Q., Namura, S., Waeber, C., and Moskowitz, M. A. (1997) J Cereb. Blood Flow Metab. 17, 1143-1151
19. Liaudet, L., Pacher, P., Mabley, J. G., Virag, L., Soriano, F. G., Hasko, G., and Szabo, C. (2002) Am. J. Respir. Crit. Care Med. 165, 372-377
20. Soriano, F. G., Liaudet, L., Szabo, E., Virag, L., Mabley, J. G., Pacher, P., and Szabo, C. (2002) Shock 17, 286-292
21. Szabo, C., Lim, L. H., Cuzzocrea, S., Getting, S. J., Zingarelli, B., Flower, R. J., Salzman, A. L., and Perretti, M. (1997) J. Exp. Med. 186, 1041-1049
22. Pieper, A. A., Brat, D. J., Krug, D. K., Watkins, C. C., Gupta, A., Blackshaw, S., Verma, A., Wang, Z. Q., and Snyder, S. H. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 3059-3064
23. Masutani, M., Suzuki, H., Kamada, N., Watanabe, M., Ueda, O., Nozaki, T., Jishage, K.-i., Watanabe, T., Sugimoto, T., Nakagama, H., Ochiya, T., and Sugimura, T. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 2301-2304
24. Burkart, V., Wang, Z. Q., Radons, J., Heller, B., Herceg, Z., Stingl, L., Wagner, E. F., and Kolb, H. (1999) Nat Med. 5, 314-319
25. Veres, B., Radnai, B., Gallyas, F., Jr., Varbiro, G., Berente, Z., Osz, E., and Sumegi, B. (2004) J. Pharmacol. Exp. Ther. 310, 247-255
26. Palfi, A., Toth, A., Kulcsar, G., Hanto, K., Deres, P., Bartha, E., Halmosi, R., Szabados, E., Czopf, L., Kalai, T., Hideg, K., Sumegi, B., and Toth, K (June, 2005) J. Pharmacol. Exp. Ther. 10.1124/jpet.105.088336
27. Murriel, C. L., Churchill, E., Inagaki, K., Szweda, L. I., and Mochly-Rosen, D. (2004) J. Biol. Chem. 279, 47985-47991
28. Halmosi, R., Berente, Z., Osz, E., Toth, K., Literati-Nagy, P., and Sumegi, B. (2001) Mol. Pharmacol. 59, 1497-1505
29. Du, L., Zhang, X., Han, Y. Y., Burke, N. A., Kochanek, P. M., Watkins, S. C., Graham, S. H., Carcillo, J. A., Szabo, C., and Clark, R. S. (2003) J. Biol. Chem. 278, 18426-18433
30. Veres, B., Gallyas, F., Jr., Varbiro, G., Berente, Z., Osz, E., Szekeres, G., Szabo, C., and Sumegi, B. (2003) Biochem. Pharmacol. 65, 1373-1382
31. Scheid, M. P., and Woodgett, J. R. (2001) Nat. Rev Mol. Cell Biol. 2, 760-768
32. Virag, L., Salzman, A. L., and Szabo, C (1998) J. Immunol. 161, 3753-3759
33. Hong, S. J., Dawson, T. M., and Dawson, V. L. (2004) Trends Pharmacol. Sci. 25, 259-264
34. Kim, J. W., Won, J., Sohn, S., and Joe, C. O. (2000) J. Cell Sci. 113, 955-961
35. Xiao, C. Y., Chen, M., Zsengeller, Z., Li, H., Kiss, L., Kollai, M., and Szabo, C. (2005) J. Pharmacol. Exp. Ther. 312, 891-898
36. Shah, G. M., Poirier, D., Duchaine, C., Brochu, G., Desnoyers, S., Lagueux, J., Verreault, A., Hoflack, J.-C., Kirkland, J. B., and Poirier, G. G. (1995) Anal. Biochem. 227, 1-13
37. Virag, L., and Szabo, C. (2002) Pharmacol. Rev. 54, 375-429
38. Kannan, P., Yu, Y., Wankhade, S., and Tainsky, M. A. (1999) Nucleic Acids Res. 27, 866-874
39. Cervellera, M. N., and Sala, A. (2000) J. Biol. Chem. 275, 10692-10696
40. Nie, J., Sakamoto, S., Song, D., Qu, Z., Ota, K., and Taniguchi, T. (1998) FEBS Lett. 424, 27-32
41. Oei, S. L., Griesenbeck, J., Schweiger, M., Babich, V., Kropotov, A., and Tomilin, N. (1997) Biochem. Biophys. Res. Commun. 240, 108-111
42. Butler, A. J., and Ordahl, C. P. (1999) Mol. Cell. Biol. 19, 296-306
43. Hassa, P. O., Covic, M., Hasan, S., Imhof, R., and Hottiger, M. O. (2001) J. Biol. Chem. 276, 45588-45597
44. Ullrich, O., Distel, A., Eyupoglu, I. Y., and Nitsch, R. (2001) Nat. Cell Biol. 3, 1035-1042
45. Kameoka, M., Ota, K., Tetsuka, T., Tanaka, Y., Itaya, A., Okamoto, T., and Yoshihara, K. (2000) Biochem. J. 346, 641-649
46. Chang, W. J., and Alvarez-Gonzalez, R. (2001) J. Biol. Chem. 276, 47664-47670
47. Wesierska-Gadek, J., and Schmid, G. (2001) Cell. Mol. Biol. Lett. 6, 117-140
48. Amstad, P. A., Krupitza, G., and Cerutti, P. A. (1992) Cancer Res. 52, 3952-3960
49. Muller, W. E., and Zahn, R. K. (1976) Mol. Cell. Biochem. 12, 147-159
50. Taniguchi, T., Suzuki, S., and Shizuta, Y. (1985) Biochem. Biophys. Res. Commun. 127, 526-532
51. Esposito, G., Ligresti, A., Izzo, A. A., Bisogno, T., Ruvo, M., Di Rosa, M., Di Marzo, V., and Iuvone, T. (2002) J. Biol. Chem. 277, 50348-50354
52. Cui, Q. L., Zheng, W. H., Quirion, R., and Almazan, G. (2005) J. Biol. Chem. 280, 8918-8928
53. Vlahos, C. J., Matter, W. F., Hui, K. Y., and Brown, R. F. (1994) J. Biol. Chem. 269, 5241-5248
54. Powis, G., Bonjouklian, R., Berggren, M. M., Gallegos, A., Abraham, R., Ashendel, C., Zalkow, L., Matter, W. F., Dodge, J., and Grindey, G. (1994) Cancer Res. 54, 2419-2423
55. Hanke, J. H., Gardner, J. P., Dow, R. L., Changelian, P. S., Brissette, W. H., Weringer, E. J., Pollok, B. A., and Connelly, P. A. (1996) J. Biol. Chem. 271, 695-701
56. Alano, C. C., Ying, W., and Swanson, R. A. (2004) J. Biol. Chem. 279, 18895-18902
57. Yu, S. W., Wang, H., Poitras, M. F., Coombs, C., Bowers, W. J., Federoff, H. J., Poirier, G. G., Dawson, T. M., and Dawson, V. L. (2002) Science 297, 259-263
58. Komjati, K., Mabley, J. G., Virag, L., Southan, G. J., Salzman, A. L., and Szabo, C. (2004) Int. J. Mol. Med. 13, 373-382
59. Chen, M., Zsengeller, Z., Xiao, C. Y., and Szabo, C. (2004) Cardiovasc. Res. 63, 682-688