-
1
-
-
77956674635
-
Evidence for an alternative glycolytic pathway in rapidly proliferating cells
-
Vander Heiden MG, Locasale JW, Swanson KD, Sharfi H, Heffron GJ. Evidence for an alternative glycolytic pathway in rapidly proliferating cells. Science 2010, 329:1492-1499.
-
(2010)
Science
, vol.329
, pp. 1492-1499
-
-
Vander Heiden, M.G.1
Locasale, J.W.2
Swanson, K.D.3
Sharfi, H.4
Heffron, G.J.5
-
2
-
-
84873681470
-
Mitochondria in vascular health and disease
-
Michelakis ED, Dromparis P. Mitochondria in vascular health and disease. Annu Rev Physiol 2013, 75:95-126.
-
(2013)
Annu Rev Physiol
, vol.75
, pp. 95-126
-
-
Michelakis, E.D.1
Dromparis, P.2
-
4
-
-
31944452442
-
Mitochondrial transfer between cells can rescue aerobic respiration
-
Spees JL, Olson SD, Whitney MJ, Prockop DJ. Mitochondrial transfer between cells can rescue aerobic respiration. Proc Natl Acad Sci U S A 2006, 103:1283-1288.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 1283-1288
-
-
Spees, J.L.1
Olson, S.D.2
Whitney, M.J.3
Prockop, D.J.4
-
5
-
-
0037972522
-
Mitochondrial respiratory-chain diseases
-
DiMauro S, Schon EA. Mitochondrial respiratory-chain diseases. N Engl J Med 2003, 348:2656-2668.
-
(2003)
N Engl J Med
, vol.348
, pp. 2656-2668
-
-
DiMauro, S.1
Schon, E.A.2
-
6
-
-
0033118649
-
Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death
-
Duchen MR. Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death. J Physiol 1999, 516:1-17.
-
(1999)
J Physiol
, vol.516
, pp. 1-17
-
-
Duchen, M.R.1
-
7
-
-
0035229427
-
The mitochondrion in apoptosis: how Pandora's box opens
-
Zamzami NKG. The mitochondrion in apoptosis: how Pandora's box opens. Nat Rev Mol Cell Biol 2001, 2:67-71.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 67-71
-
-
Zamzami, N.K.G.1
-
8
-
-
33746016268
-
Mitochondria: more than just a powerhouse
-
McBride HM, Neuspiel M, Wasiak S. Mitochondria: more than just a powerhouse. Curr Biol 2006, 16:R551-R560.
-
(2006)
Curr Biol
, vol.16
, pp. R551-R560
-
-
McBride, H.M.1
Neuspiel, M.2
Wasiak, S.3
-
9
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
-
Liu X, Kim CN, Yang J, Jemmerson R, Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 1996, 86:147-157.
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
10
-
-
78651126508
-
A case of severe hypermetabolism of nonthyroid origin with a defect in the maintenance of mitochondrial respiratory control: a correlated clinical, biochemical, and morphological study
-
Luft R, Ikkos D, Palmieri G, Ernster L, Afzelius B. A case of severe hypermetabolism of nonthyroid origin with a defect in the maintenance of mitochondrial respiratory control: a correlated clinical, biochemical, and morphological study. J Clin Invest 1962, 41:1776-1804.
-
(1962)
J Clin Invest
, vol.41
, pp. 1776-1804
-
-
Luft, R.1
Ikkos, D.2
Palmieri, G.3
Ernster, L.4
Afzelius, B.5
-
11
-
-
23844558266
-
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine
-
Wallace DC. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet 2005, 39:359-407.
-
(2005)
Annu Rev Genet
, vol.39
, pp. 359-407
-
-
Wallace, D.C.1
-
12
-
-
0035142151
-
Mitochondrial medicine-molecular pathology of defective oxidative phosphorylation
-
Fosslien E. Mitochondrial medicine-molecular pathology of defective oxidative phosphorylation. Ann Clin Lab Sci 2001, 31:25-67.
-
(2001)
Ann Clin Lab Sci
, vol.31
, pp. 25-67
-
-
Fosslien, E.1
-
13
-
-
0033994409
-
Radicals and oxidative stress in diabetes
-
West IC. Radicals and oxidative stress in diabetes. Diabet Med 2000, 17:171-180.
-
(2000)
Diabet Med
, vol.17
, pp. 171-180
-
-
West, I.C.1
-
14
-
-
26444492154
-
Molecular basis of hepatitis C virus-associated hepatocarcinogenesis: lessons from animal model studies
-
Koike K. Molecular basis of hepatitis C virus-associated hepatocarcinogenesis: lessons from animal model studies. Clin Gastroenterol Hepatol 2005, 3:S132-S135.
-
(2005)
Clin Gastroenterol Hepatol
, vol.3
, pp. S132-S135
-
-
Koike, K.1
-
15
-
-
84866665390
-
Mitochondria and cancer
-
Wallace DC. Mitochondria and cancer. Nat Rev Cancer 2012, 12:685-698.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 685-698
-
-
Wallace, D.C.1
-
16
-
-
84872172513
-
Mitochondrial dysfunction and cancer metastasis
-
Chen EI. Mitochondrial dysfunction and cancer metastasis. J Bioenerg Biomembr 2012, 44:619-622.
-
(2012)
J Bioenerg Biomembr
, vol.44
, pp. 619-622
-
-
Chen, E.I.1
-
18
-
-
13844281067
-
The powerhouse takes control of the cell: is the mitochondrial permeability transition a viable therapeutic target against neuronal dysfunction and death?
-
Stavrovskaya IG, Kristal BS. The powerhouse takes control of the cell: is the mitochondrial permeability transition a viable therapeutic target against neuronal dysfunction and death? Free Radic Biol Med 2005, 38:687-697.
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 687-697
-
-
Stavrovskaya, I.G.1
Kristal, B.S.2
-
19
-
-
21744434763
-
Mitochondrial dysfunction as an initiating event in atherogenesis: a plausible hypothesis
-
Puddu P, Puddu GM, Galletti L, Cravero E, Muscari A. Mitochondrial dysfunction as an initiating event in atherogenesis: a plausible hypothesis. Cardiology 2005, 103:137-141.
-
(2005)
Cardiology
, vol.103
, pp. 137-141
-
-
Puddu, P.1
Puddu, G.M.2
Galletti, L.3
Cravero, E.4
Muscari, A.5
-
20
-
-
18044383110
-
Mitochondrial dysfunction in cardiovascular disease
-
Ballinger SW. Mitochondrial dysfunction in cardiovascular disease. Free Radic Biol Med 2005, 38:1278-1295.
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 1278-1295
-
-
Ballinger, S.W.1
-
21
-
-
0034960785
-
Mitochondrial dysfunction in cardiac disease: ischemia-reperfusion, aging, and heart failure
-
Lesnefsky EJ, Moghaddas S, Tandler B, Kerner J, Hoppel CL. Mitochondrial dysfunction in cardiac disease: ischemia-reperfusion, aging, and heart failure. J Mol Cell Cardiol 2001, 33:1065-1089.
-
(2001)
J Mol Cell Cardiol
, vol.33
, pp. 1065-1089
-
-
Lesnefsky, E.J.1
Moghaddas, S.2
Tandler, B.3
Kerner, J.4
Hoppel, C.L.5
-
22
-
-
33947512416
-
Mitochondrial dysfunction in atherosclerosis
-
Madamanchi NR, Runge MS. Mitochondrial dysfunction in atherosclerosis. Circ Res 2007, 100:460-473.
-
(2007)
Circ Res
, vol.100
, pp. 460-473
-
-
Madamanchi, N.R.1
Runge, M.S.2
-
23
-
-
77958511649
-
DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome
-
Mercer JR, Cheng KK, Figg N, Gorenne I, Mahmoudi M, Griffin J, Vidal-Puig A, Logan A, Murphy MP, Bennett M. DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome. Circ Res 2010, 107:1021-1031.
-
(2010)
Circ Res
, vol.107
, pp. 1021-1031
-
-
Mercer, J.R.1
Cheng, K.K.2
Figg, N.3
Gorenne, I.4
Mahmoudi, M.5
Griffin, J.6
Vidal-Puig, A.7
Logan, A.8
Murphy, M.P.9
Bennett, M.10
-
24
-
-
26044471868
-
Efficacy of levo carnitine and alpha lipoic acid in ameliorating the decline in mitochondrial enzymes during aging
-
Savitha S, Sivarajan K, Haripriya D, Kokilavani V, Panneerselvam C. Efficacy of levo carnitine and alpha lipoic acid in ameliorating the decline in mitochondrial enzymes during aging. Clin Nutr 2005, 24:794-800.
-
(2005)
Clin Nutr
, vol.24
, pp. 794-800
-
-
Savitha, S.1
Sivarajan, K.2
Haripriya, D.3
Kokilavani, V.4
Panneerselvam, C.5
-
25
-
-
32244431625
-
Aging as a mitochondria-mediated atavistic program: can aging be switched off?
-
Skulachev VP, Longo VD. Aging as a mitochondria-mediated atavistic program: can aging be switched off? Ann N Y Acad Sci 2005, 1057:145-164.
-
(2005)
Ann N Y Acad Sci
, vol.1057
, pp. 145-164
-
-
Skulachev, V.P.1
Longo, V.D.2
-
26
-
-
0027171266
-
Oxidants, antioxidants, and the degenerative diseases of aging
-
Ames BN, Shigenaga MK, Hagen TM. Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci U S A 1993, 90:7915-7922.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 7915-7922
-
-
Ames, B.N.1
Shigenaga, M.K.2
Hagen, T.M.3
-
27
-
-
0026671245
-
Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease
-
Corral-Debrinski M, Shoffner JM, Lott MT, Wallace DC. Association of mitochondrial DNA damage with aging and coronary atherosclerotic heart disease. Mutat Res 1992, 275:169-180.
-
(1992)
Mutat Res
, vol.275
, pp. 169-180
-
-
Corral-Debrinski, M.1
Shoffner, J.M.2
Lott, M.T.3
Wallace, D.C.4
-
28
-
-
27144492384
-
Mitochondrial dysfunction in bipolar disorder: evidence from magnetic resonance spectroscopy research
-
Stork C, Renshaw PF. Mitochondrial dysfunction in bipolar disorder: evidence from magnetic resonance spectroscopy research. Mol Psychiatry 2005, 10:900-919.
-
(2005)
Mol Psychiatry
, vol.10
, pp. 900-919
-
-
Stork, C.1
Renshaw, P.F.2
-
29
-
-
29544442825
-
Review of the literature on major mental disorders in adult patients with mitochondrial diseases
-
Fattal O, Budur K, Vaughan AJ, Franco K. Review of the literature on major mental disorders in adult patients with mitochondrial diseases. Psychosomatics 2006, 47:1-7.
-
(2006)
Psychosomatics
, vol.47
, pp. 1-7
-
-
Fattal, O.1
Budur, K.2
Vaughan, A.J.3
Franco, K.4
-
30
-
-
27644511756
-
Increased anxiety-like behaviors and mitochondrial dysfunction in mice with targeted mutation of the Bcl-2 gene: further support for the involvement of mitochondrial function in anxiety disorders
-
Einat H, Yuan P, Manji HK. Increased anxiety-like behaviors and mitochondrial dysfunction in mice with targeted mutation of the Bcl-2 gene: further support for the involvement of mitochondrial function in anxiety disorders. Behav Brain Res 2005, 165:172-180.
-
(2005)
Behav Brain Res
, vol.165
, pp. 172-180
-
-
Einat, H.1
Yuan, P.2
Manji, H.K.3
-
31
-
-
0034672602
-
Specific oxidative alterations in vastus lateralis muscle of patients with the diagnosis of chronic fatigue syndrome
-
Fulle S, Mecocci P, Fano G, Vecchiet I, Vecchini A, Racciotti D, et al. Specific oxidative alterations in vastus lateralis muscle of patients with the diagnosis of chronic fatigue syndrome. Free Radic Biol Med 2000, 29:1252-1259.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 1252-1259
-
-
Fulle, S.1
Mecocci, P.2
Fano, G.3
Vecchiet, I.4
Vecchini, A.5
Racciotti, D.6
-
33
-
-
84903304059
-
Oxidative stress and mitochondrial dysfunction in Alzheimer's disease
-
Wang X, Wang W, Li L, Perry G, Lee HG, Zhu X. Oxidative stress and mitochondrial dysfunction in Alzheimer's disease. Biochim Biophys Acta 2014, 1842:1240-1247.
-
(2014)
Biochim Biophys Acta
, vol.1842
, pp. 1240-1247
-
-
Wang, X.1
Wang, W.2
Li, L.3
Perry, G.4
Lee, H.G.5
Zhu, X.6
-
34
-
-
25444483357
-
Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology
-
Ross MF, Kelso GF, Blaikie FH, James AM, Cochemé HM, Filipovska A, Da Ros T, Hurd TR, Smith RAJ, Murphy MP. Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology. Biochemistry (Mosc) 2005, 70:273-283.
-
(2005)
Biochemistry (Mosc)
, vol.70
, pp. 273-283
-
-
Ross, M.F.1
Kelso, G.F.2
Blaikie, F.H.3
James, A.M.4
Cochemé, H.M.5
Filipovska, A.6
Da Ros, T.7
Hurd, T.R.8
Smith, R.A.J.9
Murphy, M.P.10
-
36
-
-
84877868017
-
Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis
-
Nieminen AI, Eskelinen VM, Haikala HM, Tervonen TA, Yan Y, Partanen JI, et al. Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis. Proc Natl Acad Sci U S A 2013, 110:E1839-E1848.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. E1839-E1848
-
-
Nieminen, A.I.1
Eskelinen, V.M.2
Haikala, H.M.3
Tervonen, T.A.4
Yan, Y.5
Partanen, J.I.6
-
37
-
-
2442460088
-
Role of mitochondrial membrane permeabilization in apoptosis and cancer
-
Henry-Mowatt J, Dive C, Martinou J-C, James D. Role of mitochondrial membrane permeabilization in apoptosis and cancer. Oncogene 2004, 23:2850-2860.
-
(2004)
Oncogene
, vol.23
, pp. 2850-2860
-
-
Henry-Mowatt, J.1
Dive, C.2
Martinou, J.-C.3
James, D.4
-
38
-
-
84927178253
-
-
N-Acetyl L-Cysteine and L-Cysteine Choline Esters, and (R)-[2-(2,2-Dimethyl-thiazolidine-4-carbonyloxy)-ethyl]trimethyl-ammonium chloride, for example; compounds may be used to inhibit oxidative stress-induced cell injury or death both in vivo and ex vivo;. USPTO, PCT/US2004/039739.
-
Sheu SS, Anders MW, Xu L, Sharma VK. N-Acetyl L-Cysteine and L-Cysteine Choline Esters, and (R)-[2-(2, 2-Dimethyl-thiazolidine-4-carbonyloxy)-ethyl]trimethyl-ammonium chloride, for example; compounds may be used to inhibit oxidative stress-induced cell injury or death both in vivo and ex vivo; 2009. USPTO, PCT/US2004/039739.
-
(2009)
-
-
Sheu, S.S.1
Anders, M.W.2
Xu, L.3
Sharma, V.K.4
-
39
-
-
29344446328
-
Targeting antioxidants to mitochondria: a new therapeutic direction
-
Sheu SS, Nauduri D, Anders MW. Targeting antioxidants to mitochondria: a new therapeutic direction. Biochim Biophys Acta 2006, 1762:256-265.
-
(2006)
Biochim Biophys Acta
, vol.1762
, pp. 256-265
-
-
Sheu, S.S.1
Nauduri, D.2
Anders, M.W.3
-
40
-
-
84858149988
-
Manganese superoxide dismutase, MnSOD and its mimics
-
Miriyala S, Spasojevic I, Tovmasyan A, Salvemini D, Vujaskovic Z, St Clair D, et al. Manganese superoxide dismutase, MnSOD and its mimics. Biochim Biophys Acta 2012, 1822:794-814.
-
(2012)
Biochim Biophys Acta
, vol.1822
, pp. 794-814
-
-
Miriyala, S.1
Spasojevic, I.2
Tovmasyan, A.3
Salvemini, D.4
Vujaskovic, Z.5
St Clair, D.6
-
41
-
-
84885789945
-
Late administration of Mn porphyrin-based SOD mimic enhances diabetic complications
-
Ali DK, Oriowo M, Tovmasyan A, Batinic-Haberle I, Benov L. Late administration of Mn porphyrin-based SOD mimic enhances diabetic complications. Redox Biol 2013, 1:457-466.
-
(2013)
Redox Biol
, vol.1
, pp. 457-466
-
-
Ali, D.K.1
Oriowo, M.2
Tovmasyan, A.3
Batinic-Haberle, I.4
Benov, L.5
-
42
-
-
79953791901
-
Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumors
-
Keir ST, Dewhirst MW, Kirkpatrick JP, Bigner DD, Batinic-Haberle I. Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumors. Curr Med Chem: Anti-Cancer Agents 2011, 11:202-212.
-
(2011)
Curr Med Chem: Anti-Cancer Agents
, vol.11
, pp. 202-212
-
-
Keir, S.T.1
Dewhirst, M.W.2
Kirkpatrick, J.P.3
Bigner, D.D.4
Batinic-Haberle, I.5
-
43
-
-
80051669546
-
Neuroprotective Efficacy from a Lipophilic Redox-Modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: Rodent Models of Ischemic Stroke and Subarachnoid Hemorrhage
-
Sheng H, Spasojevic I, Tse HM, Jung JY, Hong J, Zhang Z, et al. Neuroprotective Efficacy from a Lipophilic Redox-Modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: Rodent Models of Ischemic Stroke and Subarachnoid Hemorrhage. J Pharmacol Exp Ther 2011, 338:906-916.
-
(2011)
J Pharmacol Exp Ther
, vol.338
, pp. 906-916
-
-
Sheng, H.1
Spasojevic, I.2
Tse, H.M.3
Jung, J.Y.4
Hong, J.5
Zhang, Z.6
-
44
-
-
33748757219
-
Tailoring structure-function and targeting properties of ceramides by site-specific cationization
-
Szulc ZM, Bielawski J, Gracz H, Gustilo M, Mayroo N, Hannun YA, et al. Tailoring structure-function and targeting properties of ceramides by site-specific cationization. Bioorg Med Chem 2006, 14:7083-7104.
-
(2006)
Bioorg Med Chem
, vol.14
, pp. 7083-7104
-
-
Szulc, Z.M.1
Bielawski, J.2
Gracz, H.3
Gustilo, M.4
Mayroo, N.5
Hannun, Y.A.6
-
45
-
-
77954659146
-
Mitochondria-targeted penetrating cations as carriers of hydrophobic anions through lipid membranes
-
Rokitskaya TI, Sumbatyan NV, Tashlitsky VN, Korshunova GA, Antonenko YN, Skulachev VP. Mitochondria-targeted penetrating cations as carriers of hydrophobic anions through lipid membranes. Biochim Biophys Acta 2010, 1798:1698-1706.
-
(2010)
Biochim Biophys Acta
, vol.1798
, pp. 1698-1706
-
-
Rokitskaya, T.I.1
Sumbatyan, N.V.2
Tashlitsky, V.N.3
Korshunova, G.A.4
Antonenko, Y.N.5
Skulachev, V.P.6
-
46
-
-
41949083981
-
Mitochondria-penetrating peptides
-
Horton KL, Stewart KM, Fonseca SB, Guo Q, Kelley SO. Mitochondria-penetrating peptides. Chem Biol 2008, 15:375-382.
-
(2008)
Chem Biol
, vol.15
, pp. 375-382
-
-
Horton, K.L.1
Stewart, K.M.2
Fonseca, S.B.3
Guo, Q.4
Kelley, S.O.5
-
47
-
-
66249147509
-
Engineered apoptosis-inducing peptides with enhanced mitochondrial localization and potency
-
Horton KL, Kelley SO. Engineered apoptosis-inducing peptides with enhanced mitochondrial localization and potency. J Med Chem 2009, 52:3293-3299.
-
(2009)
J Med Chem
, vol.52
, pp. 3293-3299
-
-
Horton, K.L.1
Kelley, S.O.2
-
48
-
-
84883542016
-
Tuning the intracellular bacterial targeting of peptidic vectors
-
Lei EK, Pereira MP, Kelley SO. Tuning the intracellular bacterial targeting of peptidic vectors. Angew Chem Int Ed 2013, 52:9660-9663.
-
(2013)
Angew Chem Int Ed
, vol.52
, pp. 9660-9663
-
-
Lei, E.K.1
Pereira, M.P.2
Kelley, S.O.3
-
49
-
-
84896724395
-
Molecular vehicles for mitochondrial chemical biology and drug delivery
-
Rin Jean S, Tulumello DV, Wisnovsky SP, Lei EK, Pereira MP, Kelley SO. Molecular vehicles for mitochondrial chemical biology and drug delivery. ACS Chem Biol 2014, 9:323-333.
-
(2014)
ACS Chem Biol
, vol.9
, pp. 323-333
-
-
Rin Jean, S.1
Tulumello, D.V.2
Wisnovsky, S.P.3
Lei, E.K.4
Pereira, M.P.5
Kelley, S.O.6
-
50
-
-
84876485742
-
Cellular uptake and cytotoxicity of drug-peptide conjugates regulated by conjugation site
-
Zhang P, Cheetham AG, Lock LL, Cui H. Cellular uptake and cytotoxicity of drug-peptide conjugates regulated by conjugation site. Bioconjug Chem 2013, 24:604-613.
-
(2013)
Bioconjug Chem
, vol.24
, pp. 604-613
-
-
Zhang, P.1
Cheetham, A.G.2
Lock, L.L.3
Cui, H.4
-
52
-
-
79955385201
-
Rerouting chlorambucil to mitochondria combats drug deactivation and resistance in cancer cells
-
Fonseca Sonali B, Pereira Mark P, Mourtada R, Gronda M, Horton Kristin L, Hurren R, et al. Rerouting chlorambucil to mitochondria combats drug deactivation and resistance in cancer cells. Chem Biol 2011, 18:445-453.
-
(2011)
Chem Biol
, vol.18
, pp. 445-453
-
-
Fonseca Sonali, B.1
Pereira Mark, P.2
Mourtada, R.3
Gronda, M.4
Horton Kristin, L.5
Hurren, R.6
-
53
-
-
84888286676
-
Targeting mitochondrial DNA with a platinum-based anticancer agent
-
Wisnovsky Simon P, Wilson Justin J, Radford Robert J, Pereira Mark P, Chan Maria R, Laposa Rebecca R, et al. Targeting mitochondrial DNA with a platinum-based anticancer agent. Chem Biol 2013, 20:1323-1328.
-
(2013)
Chem Biol
, vol.20
, pp. 1323-1328
-
-
Wisnovsky Simon, P.1
Wilson Justin, J.2
Radford Robert, J.3
Pereira Mark, P.4
Chan Maria, R.5
Laposa Rebecca, R.6
-
54
-
-
79952578695
-
Maximizing the therapeutic window of an antimicrobial drug by imparting mitochondrial sequestration in human cells
-
Pereira MP, Kelley SO. Maximizing the therapeutic window of an antimicrobial drug by imparting mitochondrial sequestration in human cells. J Am Chem Soc 2011, 133:3260-3263.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 3260-3263
-
-
Pereira, M.P.1
Kelley, S.O.2
-
55
-
-
0035895888
-
Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties
-
Kelso GF, Porteous CM, Coulter CV, Hughes G, Porteous WK, Ledgerwood EC, et al. Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties. J Biol Chem 2001, 276:4588-4596.
-
(2001)
J Biol Chem
, vol.276
, pp. 4588-4596
-
-
Kelso, G.F.1
Porteous, C.M.2
Coulter, C.V.3
Hughes, G.4
Porteous, W.K.5
Ledgerwood, E.C.6
-
56
-
-
0348136710
-
Mitochondria-targeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants
-
Jauslin ML, Meier T, Smith RAJ, Murphy MP. Mitochondria-targeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants. FASEB J 2003, 17:1972-1974.
-
(2003)
FASEB J
, vol.17
, pp. 1972-1974
-
-
Jauslin, M.L.1
Meier, T.2
Smith, R.A.J.3
Murphy, M.P.4
-
57
-
-
21744450416
-
Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury
-
Adlam VJ, Harrison JC, Porteous CM, James AM, Smith RAJ, Murphy MP, et al. Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury. FASEB J 2005, 19:1088-1095.
-
(2005)
FASEB J
, vol.19
, pp. 1088-1095
-
-
Adlam, V.J.1
Harrison, J.C.2
Porteous, C.M.3
James, A.M.4
Smith, R.A.J.5
Murphy, M.P.6
-
58
-
-
84878817212
-
Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death
-
Cheng G, Zielonka J, McAllister D, Mackinnon A, Joseph J, Dwinell M, et al. Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death. BMC Cancer 2013, 13:285.
-
(2013)
BMC Cancer
, vol.13
, pp. 285
-
-
Cheng, G.1
Zielonka, J.2
McAllister, D.3
Mackinnon, A.4
Joseph, J.5
Dwinell, M.6
-
59
-
-
84868005297
-
A mitochondria-targeted macrocyclic Mn(II) superoxide dismutase mimetic
-
Kelso GF, Maroz A, Cocheme HM, Logan A, Prime TA, Peskin AV, et al. A mitochondria-targeted macrocyclic Mn(II) superoxide dismutase mimetic. Chem Biol 2012, 19:1237-1246.
-
(2012)
Chem Biol
, vol.19
, pp. 1237-1246
-
-
Kelso, G.F.1
Maroz, A.2
Cocheme, H.M.3
Logan, A.4
Prime, T.A.5
Peskin, A.V.6
-
60
-
-
21244448078
-
Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic: insights into the interaction of ebselen with mitochondria
-
Filipovska A, Kelso GF, Brown SE, Beer SM, Smith RA, Murphy MP. Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic: insights into the interaction of ebselen with mitochondria. J Biol Chem 2005, 280:24113-24126.
-
(2005)
J Biol Chem
, vol.280
, pp. 24113-24126
-
-
Filipovska, A.1
Kelso, G.F.2
Brown, S.E.3
Beer, S.M.4
Smith, R.A.5
Murphy, M.P.6
-
61
-
-
0037025274
-
Selective targeting of synthetic antioxidants to mitochondria: towards a mitochondrial medicine for neurodegenerative diseases?
-
Dessolin J, Schuler M, Quinart A, De Giorgi F, Ghosez L, Ichas F. Selective targeting of synthetic antioxidants to mitochondria: towards a mitochondrial medicine for neurodegenerative diseases? Eur J Pharmacol 2002, 447:155-161.
-
(2002)
Eur J Pharmacol
, vol.447
, pp. 155-161
-
-
Dessolin, J.1
Schuler, M.2
Quinart, A.3
De Giorgi, F.4
Ghosez, L.5
Ichas, F.6
-
62
-
-
23444440170
-
Mitochondria superoxide dismutase mimetic inhibits peroxide-induced oxidative damage and apoptosis: role of mitochondrial superoxide
-
Dhanasekaran A, Kotamraju S, Karunakaran C, Kalivendi SV, Thomas S, Joseph J, et al. Mitochondria superoxide dismutase mimetic inhibits peroxide-induced oxidative damage and apoptosis: role of mitochondrial superoxide. Free Radic Biol Med 2005, 39:567-583.
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 567-583
-
-
Dhanasekaran, A.1
Kotamraju, S.2
Karunakaran, C.3
Kalivendi, S.V.4
Thomas, S.5
Joseph, J.6
-
63
-
-
0346814090
-
Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone
-
Murphy MP, Echtay KS, Blaikie FH, Asin-Cayuela J, Cocheme HM, Green K, et al. Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone. J Biol Chem 2003, 278:48534-48545.
-
(2003)
J Biol Chem
, vol.278
, pp. 48534-48545
-
-
Murphy, M.P.1
Echtay, K.S.2
Blaikie, F.H.3
Asin-Cayuela, J.4
Cocheme, H.M.5
Green, K.6
-
64
-
-
67349152289
-
Mitochondria-targeted (2-hydroxyamino-vinyl)-triphenyl-phosphonium releases NO(.) and protects mouse embryonic cells against irradiation-induced apoptosis
-
Belikova NA, Jiang J, Stoyanovsky DA, Glumac A, Bayir H, Greenberger JS, et al. Mitochondria-targeted (2-hydroxyamino-vinyl)-triphenyl-phosphonium releases NO(.) and protects mouse embryonic cells against irradiation-induced apoptosis. FEBS Lett 2009, 583:1945-1950.
-
(2009)
FEBS Lett
, vol.583
, pp. 1945-1950
-
-
Belikova, N.A.1
Jiang, J.2
Stoyanovsky, D.A.3
Glumac, A.4
Bayir, H.5
Greenberger, J.S.6
-
65
-
-
39649108431
-
Activation of NO donors in mitochondria: peroxidase metabolism of (2-hydroxyamino-vinyl)-triphenyl-phosphonium by cytochrome c releases NO and protects cells against apoptosis
-
Stoyanovsky DA, Vlasova II, Belikova NA, Kapralov A, Tyurin V, Greenberger JS, et al. Activation of NO donors in mitochondria: peroxidase metabolism of (2-hydroxyamino-vinyl)-triphenyl-phosphonium by cytochrome c releases NO and protects cells against apoptosis. FEBS Lett 2008, 582:725-728.
-
(2008)
FEBS Lett
, vol.582
, pp. 725-728
-
-
Stoyanovsky, D.A.1
Vlasova, I.I.2
Belikova, N.A.3
Kapralov, A.4
Tyurin, V.5
Greenberger, J.S.6
-
66
-
-
84897388046
-
Targeting mitochondrial cardiolipin and the cytochrome c/cardiolipin complex to promote electron transport and optimize mitochondrial ATP synthesis
-
Birk AV, Chao WM, Bracken C, Warren JD, Szeto HH. Targeting mitochondrial cardiolipin and the cytochrome c/cardiolipin complex to promote electron transport and optimize mitochondrial ATP synthesis. Br J Pharmacol 2014, 171:2017-2028.
-
(2014)
Br J Pharmacol
, vol.171
, pp. 2017-2028
-
-
Birk, A.V.1
Chao, W.M.2
Bracken, C.3
Warren, J.D.4
Szeto, H.H.5
-
67
-
-
84900872269
-
Mito-DCA: a mitochondria targeted molecular scaffold for efficacious delivery of metabolic modulator dichloroacetate
-
Pathak RK, Marrache S, Harn DA, Dhar S. Mito-DCA: a mitochondria targeted molecular scaffold for efficacious delivery of metabolic modulator dichloroacetate. ACS Chem Biol 2014, 9:1178-1187.
-
(2014)
ACS Chem Biol
, vol.9
, pp. 1178-1187
-
-
Pathak, R.K.1
Marrache, S.2
Harn, D.A.3
Dhar, S.4
-
68
-
-
84889241501
-
A selective mitochondrial-targeted chlorambucil with remarkable cytotoxicity in breast and pancreatic cancers
-
Millard M, Gallagher JD, Olenyuk BZ, Neamati N. A selective mitochondrial-targeted chlorambucil with remarkable cytotoxicity in breast and pancreatic cancers. J Med Chem 2013, 56:9170-9179.
-
(2013)
J Med Chem
, vol.56
, pp. 9170-9179
-
-
Millard, M.1
Gallagher, J.D.2
Olenyuk, B.Z.3
Neamati, N.4
-
69
-
-
84855960363
-
Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore
-
Chalmers S, Caldwell ST, Quin C, Prime TA, James AM, Cairns AG, Murphy MP, McCarron JG, Hartley RC. Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore. J Am Chem Soc 2012, 134:758-761.
-
(2012)
J Am Chem Soc
, vol.134
, pp. 758-761
-
-
Chalmers, S.1
Caldwell, S.T.2
Quin, C.3
Prime, T.A.4
James, A.M.5
Cairns, A.G.6
Murphy, M.P.7
McCarron, J.G.8
Hartley, R.C.9
-
70
-
-
84901684125
-
The synthesis and functional evaluation of a mitochondria-targeted hydrogen sulfide donor, (10-oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy)decyl)triphenylphosphonium bromide (AP39)
-
Le Trionnaire S, Perry A, Szczesny B, Szabo C, Winyard PG, Whatmore JL, et al. The synthesis and functional evaluation of a mitochondria-targeted hydrogen sulfide donor, (10-oxo-10-(4-(3-thioxo-3H-1, 2-dithiol-5-yl)phenoxy)decyl)triphenylphosphonium bromide (AP39). MedChemComm 2014, 5:728-736.
-
(2014)
MedChemComm
, vol.5
, pp. 728-736
-
-
Le Trionnaire, S.1
Perry, A.2
Szczesny, B.3
Szabo, C.4
Winyard, P.G.5
Whatmore, J.L.6
-
71
-
-
80155167926
-
Mitochondria-targeted small molecule therapeutics and probes
-
Smith RA, Hartley RC, Murphy MP. Mitochondria-targeted small molecule therapeutics and probes. Antioxid Redox Signal 2011, 15:3021-3038.
-
(2011)
Antioxid Redox Signal
, vol.15
, pp. 3021-3038
-
-
Smith, R.A.1
Hartley, R.C.2
Murphy, M.P.3
-
72
-
-
84880568313
-
Multifunctional nanoparticles for drug delivery and molecular imaging
-
Bao G, Mitragotri S, Tong S. Multifunctional nanoparticles for drug delivery and molecular imaging. Annu Rev Biomed Eng 2013, 15:253-282.
-
(2013)
Annu Rev Biomed Eng
, vol.15
, pp. 253-282
-
-
Bao, G.1
Mitragotri, S.2
Tong, S.3
-
73
-
-
84883215550
-
Nanocarriers for tracking and treating diseases
-
Marrache S, Pathak RK, Darley KL, Choi JH, Zaver D, Kolishetti N, Dhar S. Nanocarriers for tracking and treating diseases. Curr Med Chem 2013, 20:3500-3514.
-
(2013)
Curr Med Chem
, vol.20
, pp. 3500-3514
-
-
Marrache, S.1
Pathak, R.K.2
Darley, K.L.3
Choi, J.H.4
Zaver, D.5
Kolishetti, N.6
Dhar, S.7
-
74
-
-
61849153021
-
Impact of nanotechnology on drug delivery
-
Farokhzad OC, Langer R. Impact of nanotechnology on drug delivery. ACS Nano 2009, 3:16-20.
-
(2009)
ACS Nano
, vol.3
, pp. 16-20
-
-
Farokhzad, O.C.1
Langer, R.2
-
75
-
-
60549109846
-
Immunocompatibility properties of lipid-polymer hybrid nanoparticles with heterogeneous surface functional groups
-
Salvador-Morales C, Zhang L, Langer R, Farokhzad OC. Immunocompatibility properties of lipid-polymer hybrid nanoparticles with heterogeneous surface functional groups. Biomaterials 2009, 30:2231-2240.
-
(2009)
Biomaterials
, vol.30
, pp. 2231-2240
-
-
Salvador-Morales, C.1
Zhang, L.2
Langer, R.3
Farokhzad, O.C.4
-
76
-
-
77956434412
-
Nanotechnology in drug delivery and tissue engineering: from discovery to applications
-
Shi J, Votruba AR, Farokhzad OC, Langer R. Nanotechnology in drug delivery and tissue engineering: from discovery to applications. Nano Lett 2010, 10:3223-3230.
-
(2010)
Nano Lett
, vol.10
, pp. 3223-3230
-
-
Shi, J.1
Votruba, A.R.2
Farokhzad, O.C.3
Langer, R.4
-
77
-
-
84867089289
-
Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics
-
Marrache S, Dhar S. Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics. Proc Natl Acad Sci 2012, 109:16288-16293.
-
(2012)
Proc Natl Acad Sci
, vol.109
, pp. 16288-16293
-
-
Marrache, S.1
Dhar, S.2
-
78
-
-
0031683986
-
Micellar delivery system for dequalinium-a lipophilic cationic drug with anticarcinoma activity
-
Weissig V, Lizano C, Torchilin VP. Micellar delivery system for dequalinium-a lipophilic cationic drug with anticarcinoma activity. J Liposome Res 1998, 8:391-400.
-
(1998)
J Liposome Res
, vol.8
, pp. 391-400
-
-
Weissig, V.1
Lizano, C.2
Torchilin, V.P.3
-
79
-
-
84855601316
-
From serendipity to mitochondria-targeted nanocarriers
-
Weissig V. From serendipity to mitochondria-targeted nanocarriers. Pharm Res 2011, 28:2657-2668.
-
(2011)
Pharm Res
, vol.28
, pp. 2657-2668
-
-
Weissig, V.1
-
80
-
-
0141763942
-
DQAsome-mediated delivery of plasmid DNA toward mitochondria in living cells
-
D'Souza GG, Rammohan R, Cheng SM, Torchilin VP, Weissig V. DQAsome-mediated delivery of plasmid DNA toward mitochondria in living cells. J Control Release 2003, 92:189-197.
-
(2003)
J Control Release
, vol.92
, pp. 189-197
-
-
D'Souza, G.G.1
Rammohan, R.2
Cheng, S.M.3
Torchilin, V.P.4
Weissig, V.5
-
81
-
-
69949176886
-
Cell-selective mitochondrial targeting: A new approach for cancer therapy
-
Vaidya B, Paliwal R, Rai S, Khatri K, Goyal AK, Mishra N, et al. Cell-selective mitochondrial targeting: A new approach for cancer therapy. Cancer Ther 2009, 7:141-148.
-
(2009)
Cancer Ther
, vol.7
, pp. 141-148
-
-
Vaidya, B.1
Paliwal, R.2
Rai, S.3
Khatri, K.4
Goyal, A.K.5
Mishra, N.6
-
82
-
-
33847017288
-
Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging
-
Tomalia DA, Reyna LA, Svenson S. Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging. Biochem Soc Trans 2007, 35:61-67.
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 61-67
-
-
Tomalia, D.A.1
Reyna, L.A.2
Svenson, S.3
-
83
-
-
33646563152
-
Amine terminated G-6 PAMAM dendrimer and its interaction with DNA probed by Hoechst 33258
-
Choi YS, Cho TS, Kim JM, Han SW, Kim SK. Amine terminated G-6 PAMAM dendrimer and its interaction with DNA probed by Hoechst 33258. Biophys Chem 2006, 121:142-149.
-
(2006)
Biophys Chem
, vol.121
, pp. 142-149
-
-
Choi, Y.S.1
Cho, T.S.2
Kim, J.M.3
Han, S.W.4
Kim, S.K.5
-
84
-
-
84859827353
-
Surface conjugation of triphenylphosphonium to target poly(amidoamine) dendrimers to mitochondria
-
Biswas S, Dodwadkar NS, Piroyan A, Torchilin VP. Surface conjugation of triphenylphosphonium to target poly(amidoamine) dendrimers to mitochondria. Biomaterials 2012, 33:4773-4782.
-
(2012)
Biomaterials
, vol.33
, pp. 4773-4782
-
-
Biswas, S.1
Dodwadkar, N.S.2
Piroyan, A.3
Torchilin, V.P.4
-
85
-
-
84898062781
-
Mitochondrial targeting dendrimer allows efficient and safe gene delivery
-
Wang X, Shao N, Zhang Q, Cheng Y. Mitochondrial targeting dendrimer allows efficient and safe gene delivery. J Mater Chem B 2014, 2:2546-2553.
-
(2014)
J Mater Chem B
, vol.2
, pp. 2546-2553
-
-
Wang, X.1
Shao, N.2
Zhang, Q.3
Cheng, Y.4
-
86
-
-
84886095036
-
Mitochondrial delivery of doxorubicin by triphenylphosphonium-functionalized hyperbranched nanocarriers results in rapid and severe cytotoxicity
-
Theodossiou T, Sideratou Z, Katsarou M, Tsiourvas D. Mitochondrial delivery of doxorubicin by triphenylphosphonium-functionalized hyperbranched nanocarriers results in rapid and severe cytotoxicity. Pharm Res 2013, 30:2832-2842.
-
(2013)
Pharm Res
, vol.30
, pp. 2832-2842
-
-
Theodossiou, T.1
Sideratou, Z.2
Katsarou, M.3
Tsiourvas, D.4
-
87
-
-
84884272360
-
Peptide-based carbon nanotubes for mitochondrial targeting
-
Battigelli A, Russier J, Venturelli E, Fabbro C, Petronilli V, Bernardi P, et al. Peptide-based carbon nanotubes for mitochondrial targeting. Nanoscale 2013, 5:9110-9117.
-
(2013)
Nanoscale
, vol.5
, pp. 9110-9117
-
-
Battigelli, A.1
Russier, J.2
Venturelli, E.3
Fabbro, C.4
Petronilli, V.5
Bernardi, P.6
-
88
-
-
84886753316
-
Enhanced cytotoxicity to cancer cells by mitochondria-targeting MWCNTs containing platinum(IV) prodrug of cisplatin
-
Yoong SL, Wong BS, Zhou QL, Chin CF, Li J, Venkatesan T, et al. Enhanced cytotoxicity to cancer cells by mitochondria-targeting MWCNTs containing platinum(IV) prodrug of cisplatin. Biomaterials 2014, 35:748-759.
-
(2014)
Biomaterials
, vol.35
, pp. 748-759
-
-
Yoong, S.L.1
Wong, B.S.2
Zhou, Q.L.3
Chin, C.F.4
Li, J.5
Venkatesan, T.6
-
89
-
-
42349094203
-
Nanoparticles in medicine: therapeutic applications and developments
-
Zhang L, Gu FX, Chan JM, Wang AZ, Langer RS, Farokhzad OC. Nanoparticles in medicine: therapeutic applications and developments. Clin Pharmacol Ther 2008, 83:761-769.
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 761-769
-
-
Zhang, L.1
Gu, F.X.2
Chan, J.M.3
Wang, A.Z.4
Langer, R.S.5
Farokhzad, O.C.6
-
90
-
-
84856638259
-
Clinical development of liposome-based drugs: formulation, characterization, and therapeutic efficacy
-
Chang HI, Yeh MK. Clinical development of liposome-based drugs: formulation, characterization, and therapeutic efficacy. Int J Nanomedicine 2012, 7:49-60.
-
(2012)
Int J Nanomedicine
, vol.7
, pp. 49-60
-
-
Chang, H.I.1
Yeh, M.K.2
-
91
-
-
2442421428
-
Transferrin-modified liposomes equipped with a pH-sensitive fusogenic peptide: an artificial viral-like delivery system
-
Kakudo T, Chaki S, Nakase I, Akaji K, Kawakami T, Maruyama K, et al. Transferrin-modified liposomes equipped with a pH-sensitive fusogenic peptide: an artificial viral-like delivery system. Biochemistry 2004, 43:5618-5628.
-
(2004)
Biochemistry
, vol.43
, pp. 5618-5628
-
-
Kakudo, T.1
Chaki, S.2
Nakase, I.3
Akaji, K.4
Kawakami, T.5
Maruyama, K.6
-
92
-
-
0347988269
-
Fourier transformed spectral bio-imaging for studying the intracellular fate of liposomes
-
Huth U, Wieschollek A, Garini Y, Schubert R, Peschka-Suss R. Fourier transformed spectral bio-imaging for studying the intracellular fate of liposomes. Cytometry 2004, 57A:10-21.
-
(2004)
Cytometry
, vol.57 A
, pp. 10-21
-
-
Huth, U.1
Wieschollek, A.2
Garini, Y.3
Schubert, R.4
Peschka-Suss, R.5
-
93
-
-
33847618832
-
Mitochondrial drug delivery and mitochondrial disease therapy-an approach to liposome-based delivery targeted to mitochondria
-
Yamada Y, Akita H, Kogure K, Kamiya H, Harashima H. Mitochondrial drug delivery and mitochondrial disease therapy-an approach to liposome-based delivery targeted to mitochondria. Mitochondrion 2007, 7:63-71.
-
(2007)
Mitochondrion
, vol.7
, pp. 63-71
-
-
Yamada, Y.1
Akita, H.2
Kogure, K.3
Kamiya, H.4
Harashima, H.5
-
94
-
-
38349036163
-
MITO-Porter: a liposome-based carrier system for delivery of macromolecules into mitochondria via membrane fusion
-
Yamada Y, Akita H, Kamiya H, Kogure K, Yamamoto T, Shinohara Y, et al. MITO-Porter: a liposome-based carrier system for delivery of macromolecules into mitochondria via membrane fusion. Biochim Biophys Acta 2008, 1778:423-432.
-
(2008)
Biochim Biophys Acta
, vol.1778
, pp. 423-432
-
-
Yamada, Y.1
Akita, H.2
Kamiya, H.3
Kogure, K.4
Yamamoto, T.5
Shinohara, Y.6
-
95
-
-
52049115848
-
Organelle-targeted nanocarriers: specific delivery of liposomal ceramide to mitochondria enhances its cytotoxicity in vitro and in vivo
-
Boddapati SV, D'Souza GGM, Erdogan S, Torchilin VP, Weissig V. Organelle-targeted nanocarriers: specific delivery of liposomal ceramide to mitochondria enhances its cytotoxicity in vitro and in vivo. Nano Lett 2008, 8:2559-2563.
-
(2008)
Nano Lett
, vol.8
, pp. 2559-2563
-
-
Boddapati, S.V.1
D'Souza, G.G.M.2
Erdogan, S.3
Torchilin, V.P.4
Weissig, V.5
-
96
-
-
22144455351
-
Mitochondriotropic liposomes
-
Boddapati SV, Tongcharoensirikul P, Hanson RN, D'Souza GGM, Torchilin VP, Weissig V. Mitochondriotropic liposomes. J Liposome Res 2005, 15:49-58.
-
(2005)
J Liposome Res
, vol.15
, pp. 49-58
-
-
Boddapati, S.V.1
Tongcharoensirikul, P.2
Hanson, R.N.3
D'Souza, G.G.M.4
Torchilin, V.P.5
Weissig, V.6
-
97
-
-
84861604566
-
Intracellular delivery of redox cycler-doxorubicin to the mitochondria of cancer cell by folate receptor targeted mitocancerotropic liposomes
-
Malhi SS, Budhiraja A, Arora S, Chaudhari KR, Nepali K, Kumar R, et al. Intracellular delivery of redox cycler-doxorubicin to the mitochondria of cancer cell by folate receptor targeted mitocancerotropic liposomes. Int J Pharm 2012, 432:63-74.
-
(2012)
Int J Pharm
, vol.432
, pp. 63-74
-
-
Malhi, S.S.1
Budhiraja, A.2
Arora, S.3
Chaudhari, K.R.4
Nepali, K.5
Kumar, R.6
-
98
-
-
84882824819
-
In Vitro assessment of the utility of stearyl triphenyl phosphonium modified liposomes in overcoming the resistance of ovarian carcinoma Ovcar-3 cells to paclitaxel
-
Solomon MA, Shah AA, D'Souza GGM. In Vitro assessment of the utility of stearyl triphenyl phosphonium modified liposomes in overcoming the resistance of ovarian carcinoma Ovcar-3 cells to paclitaxel. Mitochondrion 2013, 13:464-472.
-
(2013)
Mitochondrion
, vol.13
, pp. 464-472
-
-
Solomon, M.A.1
Shah, A.A.2
D'Souza, G.G.M.3
-
99
-
-
79957908426
-
The use of mitochondrial targeting resveratrol liposomes modified with a dequalinium polyethylene glycol-distearoylphosphatidyl ethanolamine conjugate to induce apoptosis in resistant lung cancer cells
-
Wang X-X, Li Y-B, Yao H-J, Ju R-J, Zhang Y, Li R-J, et al. The use of mitochondrial targeting resveratrol liposomes modified with a dequalinium polyethylene glycol-distearoylphosphatidyl ethanolamine conjugate to induce apoptosis in resistant lung cancer cells. Biomaterials 2011, 32:5673-5687.
-
(2011)
Biomaterials
, vol.32
, pp. 5673-5687
-
-
Wang, X.-X.1
Li, Y.-B.2
Yao, H.-J.3
Ju, R.-J.4
Zhang, Y.5
Li, R.-J.6
-
100
-
-
84860662855
-
Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo
-
Biswas S, Dodwadkar NS, Deshpande PP, Torchilin VP. Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo. J Control Release 2012, 159:393-402.
-
(2012)
J Control Release
, vol.159
, pp. 393-402
-
-
Biswas, S.1
Dodwadkar, N.S.2
Deshpande, P.P.3
Torchilin, V.P.4
-
101
-
-
84875236608
-
The anticancer efficacy of paclitaxel liposomes modified with mitochondrial targeting conjugate in resistant lung cancer
-
Zhou J, Zhao W-Y, Ma X, Ju R-J, Li X-Y, Li N, et al. The anticancer efficacy of paclitaxel liposomes modified with mitochondrial targeting conjugate in resistant lung cancer. Biomaterials 2013, 34:3626-3638.
-
(2013)
Biomaterials
, vol.34
, pp. 3626-3638
-
-
Zhou, J.1
Zhao, W.-Y.2
Ma, X.3
Ju, R.-J.4
Li, X.-Y.5
Li, N.6
-
102
-
-
82755182721
-
A novel mitotropic oligolysine nanocarrier: Targeted delivery of covalently bound D-Luciferin to cell mitochondria
-
Theodossiou TA, Sideratou Z, Tsiourvas D, Paleos CM. A novel mitotropic oligolysine nanocarrier: Targeted delivery of covalently bound D-Luciferin to cell mitochondria. Mitochondrion 2011, 11:982-986.
-
(2011)
Mitochondrion
, vol.11
, pp. 982-986
-
-
Theodossiou, T.A.1
Sideratou, Z.2
Tsiourvas, D.3
Paleos, C.M.4
-
103
-
-
84858652159
-
Targeted polymeric therapeutic nanoparticles: design, development and clinical translation
-
Kamaly N, Xiao Z, Valencia PM, Radovic-Moreno AF, Farokhzad OC. Targeted polymeric therapeutic nanoparticles: design, development and clinical translation. Chem Soc Rev 2012, 41:2971-3010.
-
(2012)
Chem Soc Rev
, vol.41
, pp. 2971-3010
-
-
Kamaly, N.1
Xiao, Z.2
Valencia, P.M.3
Radovic-Moreno, A.F.4
Farokhzad, O.C.5
-
104
-
-
84883136637
-
Ex vivo programming of dendritic cells by mitochondria-targeted nanoparticles to produce interferon-gamma for cancer immunotherapy
-
Marrache S, Tundup S, Harn DA, Dhar S. Ex vivo programming of dendritic cells by mitochondria-targeted nanoparticles to produce interferon-gamma for cancer immunotherapy. ACS Nano 2013, 7:7392-7402.
-
(2013)
ACS Nano
, vol.7
, pp. 7392-7402
-
-
Marrache, S.1
Tundup, S.2
Harn, D.A.3
Dhar, S.4
-
105
-
-
78149260773
-
Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy
-
Kolishetti N, Dhar S, Valencia P, Lin L, Karnik R, Lippard SJ, Langer R, Farokhzad OC. Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy. Proc Natl Acad Sci U S A 2010, 107:17939-17944.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 17939-17944
-
-
Kolishetti, N.1
Dhar, S.2
Valencia, P.3
Lin, L.4
Karnik, R.5
Lippard, S.J.6
Langer, R.7
Farokhzad, O.C.8
-
106
-
-
84882585441
-
Critical evaluation of biodegradable polymers used in nanodrugs
-
Marin E, Briceno MI, Caballero-George C. Critical evaluation of biodegradable polymers used in nanodrugs. Int J Nanomedicine 2013, 8:3071-3090.
-
(2013)
Int J Nanomedicine
, vol.8
, pp. 3071-3090
-
-
Marin, E.1
Briceno, M.I.2
Caballero-George, C.3
-
107
-
-
84863416277
-
Design and evaluation of multifunctional nanocarriers for selective delivery of coenzyme Q10 to mitochondria
-
Sharma A, Soliman GM, Al-Hajaj N, Sharma R, Maysinger D, Kakkar A. Design and evaluation of multifunctional nanocarriers for selective delivery of coenzyme Q10 to mitochondria. Biomacromolecules 2012, 13:239-252.
-
(2012)
Biomacromolecules
, vol.13
, pp. 239-252
-
-
Sharma, A.1
Soliman, G.M.2
Al-Hajaj, N.3
Sharma, R.4
Maysinger, D.5
Kakkar, A.6
-
108
-
-
0037965634
-
Delivery of bioactive molecules to mitochondria in vivo
-
Smith RA, Porteous CM, Gane AM, Murphy MP. Delivery of bioactive molecules to mitochondria in vivo. Proc Natl Acad Sci U S A 2003, 100:5407-5412.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 5407-5412
-
-
Smith, R.A.1
Porteous, C.M.2
Gane, A.M.3
Murphy, M.P.4
-
109
-
-
84867071692
-
Mitochondria-targeted drug delivery
-
In:, Editors name: Ajit S. Narang, Ram I. Mahato Publisher: CRC Press.
-
Weissig V, D'Souza GGM. Mitochondria-targeted drug delivery. In: Targeted Delivery of Small Macromolecular Drugs. 2010, 255-273. Editors name: Ajit S. Narang, Ram I. Mahato Publisher: CRC Press.
-
(2010)
Targeted Delivery of Small Macromolecular Drugs
, pp. 255-273
-
-
Weissig, V.1
D'Souza, G.G.M.2
-
110
-
-
33747484566
-
Targeting dinitrophenol to mitochondria: Limitations to the development of a self-limiting mitochondrial protonophore
-
Blaikie FH, Brown SE, Samuelsson LM, Brand MD, Smith RAJ, Murphy MP. Targeting dinitrophenol to mitochondria: Limitations to the development of a self-limiting mitochondrial protonophore. Biosci Rep 2006, 26:231-243.
-
(2006)
Biosci Rep
, vol.26
, pp. 231-243
-
-
Blaikie, F.H.1
Brown, S.E.2
Samuelsson, L.M.3
Brand, M.D.4
Smith, R.A.J.5
Murphy, M.P.6
-
111
-
-
71849094328
-
Targeting mitochondrial biogenesis for preventing and treating insulin resistance in diabetes and obesity: Hope from natural mitochondrial nutrients
-
Liu JK, Shen WL, Zhao BL, Wang Y, Wertz K, Weber P, et al. Targeting mitochondrial biogenesis for preventing and treating insulin resistance in diabetes and obesity: Hope from natural mitochondrial nutrients. Adv Drug Deliv Rev 2009, 61:1343-1352.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 1343-1352
-
-
Liu, J.K.1
Shen, W.L.2
Zhao, B.L.3
Wang, Y.4
Wertz, K.5
Weber, P.6
-
112
-
-
77649188789
-
Small mitochondria-targeting molecules as anti-cancer agents
-
Wang F, Ogasawara MA, Huang P. Small mitochondria-targeting molecules as anti-cancer agents. Mol Aspects Med 2010, 31:75-92.
-
(2010)
Mol Aspects Med
, vol.31
, pp. 75-92
-
-
Wang, F.1
Ogasawara, M.A.2
Huang, P.3
-
113
-
-
77953250583
-
ApoE3 mediated poly(butyl) cyanoacrylate nanoparticles containing curcumin: Study of enhanced activity of curcumin against beta amyloid induced cytotoxicity using in vitro cell culture model
-
Mulik RS, Monkkonen J, Juvonen RO, Mahadik KR, Paradkar AR. ApoE3 mediated poly(butyl) cyanoacrylate nanoparticles containing curcumin: Study of enhanced activity of curcumin against beta amyloid induced cytotoxicity using in vitro cell culture model. Mol Pharm 2010, 7:815-825.
-
(2010)
Mol Pharm
, vol.7
, pp. 815-825
-
-
Mulik, R.S.1
Monkkonen, J.2
Juvonen, R.O.3
Mahadik, K.R.4
Paradkar, A.R.5
-
114
-
-
1542364225
-
Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro
-
Ono K, Hasegawa K, Naiki H, Yamada M. Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro. J Neurosci Res 2004, 75:742-750.
-
(2004)
J Neurosci Res
, vol.75
, pp. 742-750
-
-
Ono, K.1
Hasegawa, K.2
Naiki, H.3
Yamada, M.4
-
115
-
-
33745067215
-
Novel neuroprotective, neuritogenic and anti-amyloidogenic properties of 2,4-dinitrophenol: the gentle face of Janus
-
De Felice FG, Ferreira ST. Novel neuroprotective, neuritogenic and anti-amyloidogenic properties of 2, 4-dinitrophenol: the gentle face of Janus. IUBMB Life 2006, 58:185-191.
-
(2006)
IUBMB Life
, vol.58
, pp. 185-191
-
-
De Felice, F.G.1
Ferreira, S.T.2
-
116
-
-
78650548783
-
Stimulation of anti-tumor immunity by photodynamic therapy
-
Mroz P, Hashmi JT, Huang YY, Lange N, Hamblin MR. Stimulation of anti-tumor immunity by photodynamic therapy. Expert Rev Clin Immunol 2011, 7:75-91.
-
(2011)
Expert Rev Clin Immunol
, vol.7
, pp. 75-91
-
-
Mroz, P.1
Hashmi, J.T.2
Huang, Y.Y.3
Lange, N.4
Hamblin, M.R.5
-
117
-
-
84871731761
-
Immune stimulating photoactive hybrid nanoparticles for metastatic breast cancer
-
Marrache S, Choi JH, Tundup S, Zaver D, Harn DA, Dhar S. Immune stimulating photoactive hybrid nanoparticles for metastatic breast cancer. Integr Biol (Camb) 2013, 5:215-223.
-
(2013)
Integr Biol (Camb)
, vol.5
, pp. 215-223
-
-
Marrache, S.1
Choi, J.H.2
Tundup, S.3
Zaver, D.4
Harn, D.A.5
Dhar, S.6
-
118
-
-
84904640080
-
Detouring of cisplatin to access mitochondrial genome for overcoming resistance
-
Marrache S, Pathak RK, Dhar S. Detouring of cisplatin to access mitochondrial genome for overcoming resistance. Proc Natl Acad Sci USA. 2014, 111: 10444-10449.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 10444-10449
-
-
Marrache, S.1
Pathak, R.K.2
Dhar, S.3
|