Selective targeting of a redox-active ubiquinone to mitochondria within cells: Antioxidant and antiapoptotic properties

Journal of Biological Chemistry

Volumn 276, Issue 7, 2001, Pages 4588-4596

  Kelso, Geoffrey F ^a   Porteous, Carolyn M ^a   Coulter, Carolyn V ^a   Hughes, Gillian ^a   Porteous, William K ^a   Ledgerwood, Elizabeth C ^a   Smith, Robin A J ^a   Murphy, Michael P ^a,b  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANTS; BIOLOGICAL MEMBRANES; CARBON; CELLS; HYDROGEN PEROXIDE; LIPIDS; TUMORS;

MITOCHONDRIAL FUNCTIONS;

BIOCHEMISTRY;

CATION; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; STAUROSPORINE; TRIPHENYLPHOSPHINE; TUMOR NECROSIS FACTOR ALPHA; UBIQUINONE; ANTIOXIDANT; DRUG DERIVATIVE; MITOQUINOL; MITOQUINONE; MULTIENZYME COMPLEX; ORGANOPHOSPHORUS COMPOUND;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; COVALENT BOND; HUMAN; HUMAN CELL; LIPID BILAYER; LIPID PEROXIDATION; LIPOPHILICITY; MAMMAL CELL; MEMBRANE DAMAGE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN; ACTIVE TRANSPORT; ANIMAL; CATTLE; CELL CULTURE; CELL SURVIVAL; DRUG EFFECT; ELECTRON TRANSPORT; LEUKEMIA CELL LINE; METABOLISM; MITOCHONDRION;

ANIMALIA; MAMMALIA;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BIOLOGICAL TRANSPORT, ACTIVE; CATTLE; CELL SURVIVAL; ELECTRON TRANSPORT; HUMANS; HYDROGEN PEROXIDE; JURKAT CELLS; MITOCHONDRIA; MULTIENZYME COMPLEXES; ORGANOPHOSPHORUS COMPOUNDS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; TUMOR CELLS, CULTURED; UBIQUINONE;

EID: 0035895888     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009093200     Document Type: Article

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