-
1
-
-
34547619243
-
Mesenchymal stem cells in cancer: tumor-associated fibroblasts and cell-based delivery vehicles
-
Hall B, Dembinski J, Sasser AK, Studeny M, Andreeff M, Marini F. Mesenchymal stem cells in cancer: tumor-associated fibroblasts and cell-based delivery vehicles. Int J Hematol. 2007;86(1):8-16.
-
(2007)
Int J Hematol
, vol.86
, Issue.1
, pp. 8-16
-
-
Hall, B.1
Dembinski, J.2
Sasser, A.K.3
Studeny, M.4
Andreeff, M.5
Marini, F.6
-
2
-
-
33745713171
-
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
-
Degenhardt K, Mathew R, Beaudoin B, Bray K, Anderson D, Chen G, et al. Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell. 2006;10(1):51-64.
-
(2006)
Cancer Cell
, vol.10
, Issue.1
, pp. 51-64
-
-
Degenhardt, K.1
Mathew, R.2
Beaudoin, B.3
Bray, K.4
Anderson, D.5
Chen, G.6
-
3
-
-
34249863298
-
Autophagy suppresses tumor progression by limiting chromosomal instability
-
Mathew R, Kongara S, Beaudoin B, Karp CM, Bray K, Degenhardt K, et al. Autophagy suppresses tumor progression by limiting chromosomal instability. Genes Dev. 2007;21(11):1367-81.
-
(2007)
Genes Dev
, vol.21
, Issue.11
, pp. 1367-1381
-
-
Mathew, R.1
Kongara, S.2
Beaudoin, B.3
Karp, C.M.4
Bray, K.5
Degenhardt, K.6
-
4
-
-
84865147552
-
Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments
-
Wojtkowiak JW, Rothberg JM, Kumar V, Schramm KJ, Haller E, Proemsey JB, et al. Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments. Cancer Res. 2012;72(16):3938-47.
-
(2012)
Cancer Res
, vol.72
, Issue.16
, pp. 3938-3947
-
-
Wojtkowiak, J.W.1
Rothberg, J.M.2
Kumar, V.3
Schramm, K.J.4
Haller, E.5
Proemsey, J.B.6
-
5
-
-
79951847989
-
Principles and current strategies for targeting autophagy for cancer treatment
-
Amaravadi RK, Lippincott-Schwartz J, Yin XM, Weiss WA, Takebe N, Timmer W, et al. Principles and current strategies for targeting autophagy for cancer treatment. Clin Cancer Res. 2011;17(4):654-66.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.4
, pp. 654-666
-
-
Amaravadi, R.K.1
Lippincott-Schwartz, J.2
Yin, X.M.3
Weiss, W.A.4
Takebe, N.5
Timmer, W.6
-
6
-
-
78751556979
-
Autophagy as a therapeutic target in cancer
-
Chen N, Karantza V. Autophagy as a therapeutic target in cancer. Cancer Biol Ther. 2011;11(2):157-68.
-
(2011)
Cancer Biol Ther
, vol.11
, Issue.2
, pp. 157-168
-
-
Chen, N.1
Karantza, V.2
-
7
-
-
84864805916
-
Autophagy and cancer-issues we need to digest
-
Liu EY, Ryan KM. Autophagy and cancer-issues we need to digest. J Cell Sci. 2012;125(Pt 10):2349-58.
-
(2012)
J Cell Sci
, vol.125
, pp. 2349-2358
-
-
Liu, E.Y.1
Ryan, K.M.2
-
8
-
-
84861526009
-
Deconvoluting the context-dependent role for autophagy in cancer
-
White E. Deconvoluting the context-dependent role for autophagy in cancer. Nat Rev Cancer. 2012;12(6):401-10.
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.6
, pp. 401-410
-
-
White, E.1
-
9
-
-
48249156591
-
Autophagy: an emerging target for cancer therapy
-
Hoyer-Hansen M, Jaattela M. Autophagy: an emerging target for cancer therapy. Autophagy. 2008;4(5):574-80.
-
(2008)
Autophagy
, vol.4
, Issue.5
, pp. 574-580
-
-
Hoyer-Hansen, M.1
Jaattela, M.2
-
10
-
-
67650021571
-
Autophagy-A double-edged sword in oncology
-
Apel A, Zentgraf H, Buchler MW, Herr I. Autophagy-A double-edged sword in oncology. Int J Cancer. 2009;125(5):991-5.
-
(2009)
Int J Cancer
, vol.125
, Issue.5
, pp. 991-995
-
-
Apel, A.1
Zentgraf, H.2
Buchler, M.W.3
Herr, I.4
-
11
-
-
67549110195
-
A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy
-
Mercer CA, Kaliappan A, Dennis PB. A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy. Autophagy. 2009;5(5):649-62.
-
(2009)
Autophagy
, vol.5
, Issue.5
, pp. 649-662
-
-
Mercer, C.A.1
Kaliappan, A.2
Dennis, P.B.3
-
12
-
-
65249176304
-
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
-
Jung CH, Jun CB, Ro SH, Kim YM, Otto NM, Cao J, et al. ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol Biol Cell. 2009;20(7):1992-2003.
-
(2009)
Mol Biol Cell
, vol.20
, Issue.7
, pp. 1992-2003
-
-
Jung, C.H.1
Jun, C.B.2
Ro, S.H.3
Kim, Y.M.4
Otto, N.M.5
Cao, J.6
-
13
-
-
84879780600
-
Autophagy: shaping the tumor microenvironment and therapeutic response
-
Maes H, Rubio N, Garg AD, Agostinis P. Autophagy: shaping the tumor microenvironment and therapeutic response. Trends Mol Med. 2013;19(7):428-46.
-
(2013)
Trends Mol Med
, vol.19
, Issue.7
, pp. 428-446
-
-
Maes, H.1
Rubio, N.2
Garg, A.D.3
Agostinis, P.4
-
14
-
-
77950501014
-
mTOR regulation of autophagy
-
Jung CH, Ro SH, Cao J, Otto NM, Kim DH. mTOR regulation of autophagy. FEBS Lett. 2010;584(7):1287-95.
-
(2010)
FEBS Lett
, vol.584
, Issue.7
, pp. 1287-1295
-
-
Jung, C.H.1
Ro, S.H.2
Cao, J.3
Otto, N.M.4
Kim, D.H.5
-
15
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim J, Kundu M, Viollet B, Guan KL. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol. 2011;13(2):132-41.
-
(2011)
Nat Cell Biol
, vol.13
, Issue.2
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
16
-
-
51049118332
-
The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. 'Protein modifications: beyond the usual suspects' review series
-
Geng J, Klionsky DJ. The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. 'Protein modifications: beyond the usual suspects' review series. EMBO Rep. 2008;9(9):859-64.
-
(2008)
EMBO Rep
, vol.9
, Issue.9
, pp. 859-864
-
-
Geng, J.1
Klionsky, D.J.2
-
17
-
-
0038325675
-
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate
-
Mizushima N, Kuma A, Kobayashi Y, Yamamoto A, Matsubae M, Takao T, et al. Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate. J Cell Sci. 2003;116(Pt 9):1679-88.
-
(2003)
J Cell Sci
, vol.116
, pp. 1679-1688
-
-
Mizushima, N.1
Kuma, A.2
Kobayashi, Y.3
Yamamoto, A.4
Matsubae, M.5
Takao, T.6
-
18
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J. 2000;19(21):5720-8.
-
(2000)
EMBO J
, vol.19
, Issue.21
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
Noda, T.6
-
19
-
-
25444440875
-
The role of autophagy in cancer development and response to therapy
-
Kondo Y, Kanzawa T, Sawaya R, Kondo S. The role of autophagy in cancer development and response to therapy. Nat Rev Cancer. 2005;5(9):726-34.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.9
, pp. 726-734
-
-
Kondo, Y.1
Kanzawa, T.2
Sawaya, R.3
Kondo, S.4
-
20
-
-
73349129343
-
An overview of highly optically pure chloramphenicol bases: applications and modifications
-
Yang K, Fang H, Gong J, Su L, Xu W. An overview of highly optically pure chloramphenicol bases: applications and modifications. Mini Rev Med Chem. 2009;9(11):1329-41.
-
(2009)
Mini Rev Med Chem
, vol.9
, Issue.11
, pp. 1329-1341
-
-
Yang, K.1
Fang, H.2
Gong, J.3
Su, L.4
Xu, W.5
-
21
-
-
78649338141
-
Autophagy and the integrated stress response
-
Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Mol Cell. 2010;40(2):280-93.
-
(2010)
Mol Cell
, vol.40
, Issue.2
, pp. 280-293
-
-
Kroemer, G.1
Marino, G.2
Levine, B.3
-
22
-
-
34447506424
-
Detection and characterization of tumor hypoxia using pO2 histography
-
Vaupel P, Hockel M, Mayer A. Detection and characterization of tumor hypoxia using pO2 histography. Antioxid Redox Signal. 2007;9(8):1221-35.
-
(2007)
Antioxid Redox Signal
, vol.9
, Issue.8
, pp. 1221-1235
-
-
Vaupel, P.1
Hockel, M.2
Mayer, A.3
-
23
-
-
16844379943
-
Hypoxia and anemia: effects on tumor biology and treatment resistance
-
Vaupel P, Mayer A. Hypoxia and anemia: effects on tumor biology and treatment resistance. Transfus Clin Biol. 2005;12(1):5-10.
-
(2005)
Transfus Clin Biol
, vol.12
, Issue.1
, pp. 5-10
-
-
Vaupel, P.1
Mayer, A.2
-
24
-
-
0036021479
-
Hypoxia in breast cancer: pathogenesis, characterization and biological/therapeutic implications
-
Vaupel P, Briest S, Hockel M. Hypoxia in breast cancer: pathogenesis, characterization and biological/therapeutic implications. Wien Med Wochenschr. 2002;152(13-14):334-42.
-
(2002)
Wien Med Wochenschr
, vol.152
, Issue.13-14
, pp. 334-342
-
-
Vaupel, P.1
Briest, S.2
Hockel, M.3
-
25
-
-
1642565876
-
Tumor hypoxia and malignant progression
-
Vaupel P, Mayer A, Hockel M. Tumor hypoxia and malignant progression. Methods Enzymol. 2004;381:335-54.
-
(2004)
Methods Enzymol
, vol.381
, pp. 335-354
-
-
Vaupel, P.1
Mayer, A.2
Hockel, M.3
-
26
-
-
3142587028
-
Tumor microenvironmental physiology and its implications for radiation oncology
-
Vaupel P. Tumor microenvironmental physiology and its implications for radiation oncology. Semin Radiat Oncol. 2004;14(3):198-206.
-
(2004)
Semin Radiat Oncol
, vol.14
, Issue.3
, pp. 198-206
-
-
Vaupel, P.1
-
27
-
-
78649364332
-
Hypoxia-inducible factors and the response to hypoxic stress
-
Majmundar AJ, Wong WJ, Simon MC. Hypoxia-inducible factors and the response to hypoxic stress. Mol Cell. 2010;40(2):294-309.
-
(2010)
Mol Cell
, vol.40
, Issue.2
, pp. 294-309
-
-
Majmundar, A.J.1
Wong, W.J.2
Simon, M.C.3
-
28
-
-
77951228508
-
Hypoxia-induced autophagy: cell death or cell survival?
-
Mazure NM, Pouyssegur J. Hypoxia-induced autophagy: cell death or cell survival? Curr Opin Cell Biol. 2010;22(2):177-80.
-
(2010)
Curr Opin Cell Biol
, vol.22
, Issue.2
, pp. 177-180
-
-
Mazure, N.M.1
Pouyssegur, J.2
-
29
-
-
69449107689
-
Atypical BH3-domains of BNIP3 and BNIP3L lead to autophagy in hypoxia
-
Mazure NM, Pouyssegur J. Atypical BH3-domains of BNIP3 and BNIP3L lead to autophagy in hypoxia. Autophagy. 2009;5(6):868-9.
-
(2009)
Autophagy
, vol.5
, Issue.6
, pp. 868-869
-
-
Mazure, N.M.1
Pouyssegur, J.2
-
30
-
-
47049100413
-
Essential role for Nix in autophagic maturation of erythroid cells
-
Sandoval H, Thiagarajan P, Dasgupta SK, Schumacher A, Prchal JT, Chen M, et al. Essential role for Nix in autophagic maturation of erythroid cells. Nature. 2008;454(7201):232-5.
-
(2008)
Nature
, vol.454
, Issue.7201
, pp. 232-235
-
-
Sandoval, H.1
Thiagarajan, P.2
Dasgupta, S.K.3
Schumacher, A.4
Prchal, J.T.5
Chen, M.6
-
31
-
-
66349121718
-
Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains
-
Bellot G, Garcia-Medina R, Gounon P, Chiche J, Roux D, Pouyssegur J, et al. Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains. Mol Cell Biol. 2009;29(10):2570-81.
-
(2009)
Mol Cell Biol
, vol.29
, Issue.10
, pp. 2570-2581
-
-
Bellot, G.1
Garcia-Medina, R.2
Gounon, P.3
Chiche, J.4
Roux, D.5
Pouyssegur, J.6
-
32
-
-
36448940798
-
FoxO3 controls autophagy in skeletal muscle in vivo
-
Mammucari C, Milan G, Romanello V, Masiero E, Rudolf R, Del Piccolo P, et al. FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab. 2007;6(6):458-71.
-
(2007)
Cell Metab
, vol.6
, Issue.6
, pp. 458-471
-
-
Mammucari, C.1
Milan, G.2
Romanello, V.3
Masiero, E.4
Rudolf, R.5
Piccolo, P.6
-
33
-
-
84874192375
-
FOXO3A directs a protective autophagy program in haematopoietic stem cells
-
Warr MR, Binnewies M, Flach J, Reynaud D, Garg T, Malhotra R, et al. FOXO3A directs a protective autophagy program in haematopoietic stem cells. Nature. 2013;494(7437):323-7.
-
(2013)
Nature
, vol.494
, Issue.7437
, pp. 323-327
-
-
Warr, M.R.1
Binnewies, M.2
Flach, J.3
Reynaud, D.4
Garg, T.5
Malhotra, R.6
-
34
-
-
59449103444
-
Autophagy in mineralizing tissues: microenvironmental perspectives
-
Srinivas V, Bohensky J, Zahm AM, Shapiro IM. Autophagy in mineralizing tissues: microenvironmental perspectives. Cell Cycle. 2009;8(3):391-3.
-
(2009)
Cell Cycle
, vol.8
, Issue.3
, pp. 391-393
-
-
Srinivas, V.1
Bohensky, J.2
Zahm, A.M.3
Shapiro, I.M.4
-
36
-
-
68349135032
-
Regulation of autophagy through multiple independent hypoxic signaling pathways
-
Rouschop KM, Wouters BG. Regulation of autophagy through multiple independent hypoxic signaling pathways. Curr Mol Med. 2009;9(4):417-24.
-
(2009)
Curr Mol Med
, vol.9
, Issue.4
, pp. 417-424
-
-
Rouschop, K.M.1
Wouters, B.G.2
-
37
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumour regression
-
Pouyssegur J, Dayan F, Mazure NM. Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature. 2006;441(7092):437-43.
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 437-443
-
-
Pouyssegur, J.1
Dayan, F.2
Mazure, N.M.3
-
38
-
-
74949118681
-
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
-
Rouschop KM, van den Beucken T, Dubois L, Niessen H, Bussink J, Savelkouls K, et al. The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. J Clin Invest. 2010;120(1):127-41.
-
(2010)
J Clin Invest
, vol.120
, Issue.1
, pp. 127-141
-
-
Rouschop, K.M.1
Beucken, T.2
Dubois, L.3
Niessen, H.4
Bussink, J.5
Savelkouls, K.6
-
39
-
-
35448980704
-
Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation
-
Sato K, Tsuchihara K, Fujii S, Sugiyama M, Goya T, Atomi Y, et al. Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation. Cancer Res. 2007;67(20):9677-84.
-
(2007)
Cancer Res
, vol.67
, Issue.20
, pp. 9677-9684
-
-
Sato, K.1
Tsuchihara, K.2
Fujii, S.3
Sugiyama, M.4
Goya, T.5
Atomi, Y.6
-
41
-
-
33846244269
-
Role of autophagy in cancer: management of metabolic stress
-
Jin S, White E. Role of autophagy in cancer: management of metabolic stress. Autophagy. 2007;3(1):28-31.
-
(2007)
Autophagy
, vol.3
, Issue.1
, pp. 28-31
-
-
Jin, S.1
White, E.2
-
42
-
-
77957666080
-
Glutaminolysis yields a metabolic by-product that stimulates autophagy
-
Eng CH, Abraham RT. Glutaminolysis yields a metabolic by-product that stimulates autophagy. Autophagy. 2010;6(7):968-70.
-
(2010)
Autophagy
, vol.6
, Issue.7
, pp. 968-970
-
-
Eng, C.H.1
Abraham, R.T.2
-
43
-
-
53849119118
-
Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism
-
Liao XH, Majithia A, Huang X, Kimmel AR. Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism. Amino Acids. 2008;35(4):761-70.
-
(2008)
Amino Acids
, vol.35
, Issue.4
, pp. 761-770
-
-
Liao, X.H.1
Majithia, A.2
Huang, X.3
Kimmel, A.R.4
-
44
-
-
69249229790
-
Simian virus 40 small T antigen activates AMPK and triggers autophagy to protect cancer cells from nutrient deprivation
-
Kumar SH, Rangarajan A. Simian virus 40 small T antigen activates AMPK and triggers autophagy to protect cancer cells from nutrient deprivation. J Virol. 2009;83(17):8565-74.
-
(2009)
J Virol
, vol.83
, Issue.17
, pp. 8565-8574
-
-
Kumar, S.H.1
Rangarajan, A.2
-
45
-
-
77952241179
-
Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes
-
Marambio P, Toro B, Sanhueza C, Troncoso R, Parra V, Verdejo H, et al. Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes. Biochim Biophys Acta. 2010;1802(6):509-18.
-
(2010)
Biochim Biophys Acta
, vol.1802
, Issue.6
, pp. 509-518
-
-
Marambio, P.1
Toro, B.2
Sanhueza, C.3
Troncoso, R.4
Parra, V.5
Verdejo, H.6
-
46
-
-
77949542302
-
The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival
-
Kang R, Tang D, Schapiro NE, Livesey KM, Farkas A, Loughran P, et al. The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival. Cell Death Differ. 2010;17(4):666-76.
-
(2010)
Cell Death Differ
, vol.17
, Issue.4
, pp. 666-676
-
-
Kang, R.1
Tang, D.2
Schapiro, N.E.3
Livesey, K.M.4
Farkas, A.5
Loughran, P.6
-
47
-
-
77949817711
-
AMPK and SIRT1: a long-standing partnership?
-
Ruderman NB, Xu XJ, Nelson L, Cacicedo JM, Saha AK, Lan F, et al. AMPK and SIRT1: a long-standing partnership? Am J Physiol Endocrinol Metab. 2010;298(4):E751-760.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
, Issue.4
, pp. E751-760
-
-
Ruderman, N.B.1
Xu, X.J.2
Nelson, L.3
Cacicedo, J.M.4
Saha, A.K.5
Lan, F.6
-
48
-
-
43049139914
-
Inflammation and tumor microenvironments: defining the migratory itinerary of mesenchymal stem cells
-
Spaeth E, Klopp A, Dembinski J, Andreeff M, Marini F. Inflammation and tumor microenvironments: defining the migratory itinerary of mesenchymal stem cells. Gene Ther. 2008;15(10):730-8.
-
(2008)
Gene Ther
, vol.15
, Issue.10
, pp. 730-738
-
-
Spaeth, E.1
Klopp, A.2
Dembinski, J.3
Andreeff, M.4
Marini, F.5
-
49
-
-
0035901090
-
Inflammation and cancer: back to Virchow?
-
Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet. 2001;357(9255):539-45.
-
(2001)
Lancet
, vol.357
, Issue.9255
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
50
-
-
35648983903
-
Inflammation and cancer: an ancient link with novel potentials
-
Hussain SP, Harris CC. Inflammation and cancer: an ancient link with novel potentials. Int J Cancer. 2007;121(11):2373-80.
-
(2007)
Int J Cancer
, vol.121
, Issue.11
, pp. 2373-2380
-
-
Hussain, S.P.1
Harris, C.C.2
-
51
-
-
53549102755
-
The tumor microenvironment and its role in promoting tumor growth
-
Whiteside TL. The tumor microenvironment and its role in promoting tumor growth. Oncogene. 2008;27(45):5904-12.
-
(2008)
Oncogene
, vol.27
, Issue.45
, pp. 5904-5912
-
-
Whiteside, T.L.1
-
52
-
-
79960122931
-
Dual roles of immune cells and their factors in cancer development and progression
-
Zamarron BF, Chen W. Dual roles of immune cells and their factors in cancer development and progression. Int J Biol Sci. 2011;7(5):651-8.
-
(2011)
Int J Biol Sci
, vol.7
, Issue.5
, pp. 651-658
-
-
Zamarron, B.F.1
Chen, W.2
-
53
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646-74.
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
54
-
-
84921635249
-
Autophagy is an inflammation-related defensive mechanism against disease
-
Joven J, Guirro M, Marine-Casado R, Rodriguez-Gallego E, Menendez JA. Autophagy is an inflammation-related defensive mechanism against disease. Adv Exp Med Biol. 2014;824:43-59.
-
(2014)
Adv Exp Med Biol
, vol.824
, pp. 43-59
-
-
Joven, J.1
Guirro, M.2
Marine-Casado, R.3
Rodriguez-Gallego, E.4
Menendez, J.A.5
-
55
-
-
77956400210
-
Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFkappaB activation in the tumor stromal microenvironment
-
Martinez-Outschoorn UE, Trimmer C, Lin Z, Whitaker-Menezes D, Chiavarina B, Zhou J, et al. Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFkappaB activation in the tumor stromal microenvironment. Cell Cycle. 2010;9(17):3515-33.
-
(2010)
Cell Cycle
, vol.9
, Issue.17
, pp. 3515-3533
-
-
Martinez-Outschoorn, U.E.1
Trimmer, C.2
Lin, Z.3
Whitaker-Menezes, D.4
Chiavarina, B.5
Zhou, J.6
-
56
-
-
77954162846
-
Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells
-
Martinez-Outschoorn UE, Balliet RM, Rivadeneira DB, Chiavarina B, Pavlides S, Wang C, et al. Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells. Cell Cycle. 2010;9(16):3256-76.
-
(2010)
Cell Cycle
, vol.9
, Issue.16
, pp. 3256-3276
-
-
Martinez-Outschoorn, U.E.1
Balliet, R.M.2
Rivadeneira, D.B.3
Chiavarina, B.4
Pavlides, S.5
Wang, C.6
-
57
-
-
77956399348
-
HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis
-
Chiavarina B, Whitaker-Menezes D, Migneco G, Martinez-Outschoorn UE, Pavlides S, Howell A, et al. HIF1-alpha functions as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis. Cell Cycle. 2010;9(17):3534-51.
-
(2010)
Cell Cycle
, vol.9
, Issue.17
, pp. 3534-3551
-
-
Chiavarina, B.1
Whitaker-Menezes, D.2
Migneco, G.3
Martinez-Outschoorn, U.E.4
Pavlides, S.5
Howell, A.6
-
58
-
-
79957902168
-
Cytokine production and inflammation drive autophagy in the tumor microenvironment: role of stromal caveolin-1 as a key regulator
-
Martinez-Outschoorn UE, Whitaker-Menezes D, Lin Z, Flomenberg N, Howell A, Pestell RG, et al. Cytokine production and inflammation drive autophagy in the tumor microenvironment: role of stromal caveolin-1 as a key regulator. Cell Cycle. 2011;10(11):1784-93.
-
(2011)
Cell Cycle
, vol.10
, Issue.11
, pp. 1784-1793
-
-
Martinez-Outschoorn, U.E.1
Whitaker-Menezes, D.2
Lin, Z.3
Flomenberg, N.4
Howell, A.5
Pestell, R.G.6
-
59
-
-
0036222549
-
Sensing the environment: a historical perspective on integrin signal transduction
-
Miranti CK, Brugge JS. Sensing the environment: a historical perspective on integrin signal transduction. Nat Cell Biol. 2002;4(4):E83-90.
-
(2002)
Nat Cell Biol
, vol.4
, Issue.4
, pp. E83-90
-
-
Miranti, C.K.1
Brugge, J.S.2
-
61
-
-
41449114759
-
Detachment-induced autophagy during anoikis and lumen formation in epithelial acini
-
Debnath J. Detachment-induced autophagy during anoikis and lumen formation in epithelial acini. Autophagy. 2008;4(3):351-3.
-
(2008)
Autophagy
, vol.4
, Issue.3
, pp. 351-353
-
-
Debnath, J.1
-
62
-
-
50849088969
-
Extracellular matrix regulation of autophagy
-
Lock R, Debnath J. Extracellular matrix regulation of autophagy. Curr Opin Cell Biol. 2008;20(5):583-8.
-
(2008)
Curr Opin Cell Biol
, vol.20
, Issue.5
, pp. 583-588
-
-
Lock, R.1
Debnath, J.2
-
63
-
-
78650850705
-
Regulation of autophagy by extracellular matrix glycoproteins in HeLa cells
-
Tuloup-Minguez V, Greffard A, Codogno P, Botti J. Regulation of autophagy by extracellular matrix glycoproteins in HeLa cells. Autophagy. 2011;7(1):27-39.
-
(2011)
Autophagy
, vol.7
, Issue.1
, pp. 27-39
-
-
Tuloup-Minguez, V.1
Greffard, A.2
Codogno, P.3
Botti, J.4
-
64
-
-
0037020196
-
The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini
-
Debnath J, Mills KR, Collins NL, Reginato MJ, Muthuswamy SK, Brugge JS. The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. Cell. 2002;111(1):29-40.
-
(2002)
Cell
, vol.111
, Issue.1
, pp. 29-40
-
-
Debnath, J.1
Mills, K.R.2
Collins, N.L.3
Reginato, M.J.4
Muthuswamy, S.K.5
Brugge, J.S.6
-
65
-
-
41449109334
-
Induction of autophagy during extracellular matrix detachment promotes cell survival
-
Fung C, Lock R, Gao S, Salas E, Debnath J. Induction of autophagy during extracellular matrix detachment promotes cell survival. Mol Biol Cell. 2008;19(3):797-806.
-
(2008)
Mol Biol Cell
, vol.19
, Issue.3
, pp. 797-806
-
-
Fung, C.1
Lock, R.2
Gao, S.3
Salas, E.4
Debnath, J.5
-
66
-
-
84883004080
-
IkappaB kinase complex (IKK) triggers detachment-induced autophagy in mammary epithelial cells independently of the PI3K-AKT-MTORC1 pathway
-
Chen N, Debnath J. IkappaB kinase complex (IKK) triggers detachment-induced autophagy in mammary epithelial cells independently of the PI3K-AKT-MTORC1 pathway. Autophagy. 2013;9(8):1214-27.
-
(2013)
Autophagy
, vol.9
, Issue.8
, pp. 1214-1227
-
-
Chen, N.1
Debnath, J.2
-
67
-
-
84855465222
-
Role of autophagy in angiogenesis in aortic endothelial cells
-
Du J, Teng RJ, Guan T, Eis A, Kaul S, Konduri GG, et al. Role of autophagy in angiogenesis in aortic endothelial cells. Am J Physiol Cell Physiol. 2012;302(2):C383-391.
-
(2012)
Am J Physiol Cell Physiol
, vol.302
, Issue.2
, pp. C383-391
-
-
Du, J.1
Teng, R.J.2
Guan, T.3
Eis, A.4
Kaul, S.5
Konduri, G.G.6
-
68
-
-
83955162908
-
High mobility group box 1 promotes endothelial cell angiogenic behavior in vitro and improves muscle perfusion in vivo in response to ischemic injury
-
Sachdev U, Cui X, Hong G, Namkoong S, Karlsson JM, Baty CJ, et al. High mobility group box 1 promotes endothelial cell angiogenic behavior in vitro and improves muscle perfusion in vivo in response to ischemic injury. J Vasc Surg. 2012;55(1):180-91.
-
(2012)
J Vasc Surg
, vol.55
, Issue.1
, pp. 180-191
-
-
Sachdev, U.1
Cui, X.2
Hong, G.3
Namkoong, S.4
Karlsson, J.M.5
Baty, C.J.6
-
69
-
-
78649242978
-
HMGB1: a novel Beclin 1-binding protein active in autophagy
-
Kang R, Livesey KM, Zeh HJ, Loze MT, Tang D. HMGB1: a novel Beclin 1-binding protein active in autophagy. Autophagy. 2010;6(8):1209-11.
-
(2010)
Autophagy
, vol.6
, Issue.8
, pp. 1209-1211
-
-
Kang, R.1
Livesey, K.M.2
Zeh, H.J.3
Loze, M.T.4
Tang, D.5
-
70
-
-
79961101955
-
Cancer cells metabolically fertilize the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors
-
Martinez-Outschoorn UE, Lin Z, Trimmer C, Flomenberg N, Wang C, Pavlides S, et al. Cancer cells metabolically fertilize the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: implications for PET imaging of human tumors. Cell Cycle. 2011;10(15):2504-20.
-
(2011)
Cell Cycle
, vol.10
, Issue.15
, pp. 2504-2520
-
-
Martinez-Outschoorn, U.E.1
Lin, Z.2
Trimmer, C.3
Flomenberg, N.4
Wang, C.5
Pavlides, S.6
-
71
-
-
84862886876
-
Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production
-
Capparelli C, Guido C, Whitaker-Menezes D, Bonuccelli G, Balliet R, Pestell TG, et al. Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production. Cell Cycle. 2012;11(12):2285-302.
-
(2012)
Cell Cycle
, vol.11
, Issue.12
, pp. 2285-2302
-
-
Capparelli, C.1
Guido, C.2
Whitaker-Menezes, D.3
Bonuccelli, G.4
Balliet, R.5
Pestell, T.G.6
-
72
-
-
84865800743
-
Autophagy is a protective mechanism for human melanoma cells under acidic stress
-
Marino ML, Pellegrini P, Di Lernia G, Djavaheri-Mergny M, Brnjic S, Zhang X, et al. Autophagy is a protective mechanism for human melanoma cells under acidic stress. J Biol Chem. 2012;287(36):30664-76.
-
(2012)
J Biol Chem
, vol.287
, Issue.36
, pp. 30664-30676
-
-
Marino, M.L.1
Pellegrini, P.2
Lernia, G.3
Djavaheri-Mergny, M.4
Brnjic, S.5
Zhang, X.6
-
73
-
-
0037376877
-
Angiogenesis and apoptosis
-
Folkman J. Angiogenesis and apoptosis. Semin Cancer Biol. 2003;13(2):159-67.
-
(2003)
Semin Cancer Biol
, vol.13
, Issue.2
, pp. 159-167
-
-
Folkman, J.1
-
74
-
-
12944303650
-
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
-
Lum JJ, Bauer DE, Kong M, Harris MH, Li C, Lindsten T, et al. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell. 2005;120(2):237-48.
-
(2005)
Cell
, vol.120
, Issue.2
, pp. 237-248
-
-
Lum, J.J.1
Bauer, D.E.2
Kong, M.3
Harris, M.H.4
Li, C.5
Lindsten, T.6
-
75
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
Qu X, Yu J, Bhagat G, Furuya N, Hibshoosh H, Troxel A, et al. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest. 2003;112(12):1809-20.
-
(2003)
J Clin Invest
, vol.112
, Issue.12
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
Furuya, N.4
Hibshoosh, H.5
Troxel, A.6
-
76
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
Yue Z, Jin S, Yang C, Levine AJ, Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci U S A. 2003;100(25):15077-82.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.25
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
77
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H, et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature. 1999;402(6762):672-6.
-
(1999)
Nature
, vol.402
, Issue.6762
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
-
78
-
-
61649086413
-
Regulation of HMGB1 release by autophagy
-
Thorburn J, Frankel AE, Thorburn A. Regulation of HMGB1 release by autophagy. Autophagy. 2009;5(2):247-9.
-
(2009)
Autophagy
, vol.5
, Issue.2
, pp. 247-249
-
-
Thorburn, J.1
Frankel, A.E.2
Thorburn, A.3
-
79
-
-
69949106925
-
The double-edged sword of autophagy modulation in cancer
-
White E, DiPaola RS. The double-edged sword of autophagy modulation in cancer. Clin Cancer Res. 2009;15(17):5308-16.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.17
, pp. 5308-5316
-
-
White, E.1
DiPaola, R.S.2
-
80
-
-
42449123761
-
Expansion and evolution of cell death programmes
-
Degterev A, Yuan J. Expansion and evolution of cell death programmes. Nat Rev Mol Cell Biol. 2008;9(5):378-90.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.5
, pp. 378-390
-
-
Degterev, A.1
Yuan, J.2
-
81
-
-
84861684979
-
Autophagy is a survival force via suppression of necrotic cell death
-
Shen HM, Codogno P. Autophagy is a survival force via suppression of necrotic cell death. Exp Cell Res. 2012;318(11):1304-8.
-
(2012)
Exp Cell Res
, vol.318
, Issue.11
, pp. 1304-1308
-
-
Shen, H.M.1
Codogno, P.2
-
82
-
-
58149380360
-
PARP-1 is involved in autophagy induced by DNA damage
-
Munoz-Gamez JA, Rodriguez-Vargas JM, Quiles-Perez R, Aguilar-Quesada R, Martin-Oliva D, de Murcia G, et al. PARP-1 is involved in autophagy induced by DNA damage. Autophagy. 2009;5(1):61-74.
-
(2009)
Autophagy
, vol.5
, Issue.1
, pp. 61-74
-
-
Munoz-Gamez, J.A.1
Rodriguez-Vargas, J.M.2
Quiles-Perez, R.3
Aguilar-Quesada, R.4
Martin-Oliva, D.5
Murcia, G.6
Menissier de Murcia, J.7
Almendros, A.8
Ruiz de Almodovar, M.9
Oliver, F.J.10
-
83
-
-
4644324186
-
NF-kappaB functions as a tumour promoter in inflammation-associated cancer
-
Pikarsky E, Porat RM, Stein I, Abramovitch R, Amit S, Kasem S, et al. NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature. 2004;431(7007):461-6.
-
(2004)
Nature
, vol.431
, Issue.7007
, pp. 461-466
-
-
Pikarsky, E.1
Porat, R.M.2
Stein, I.3
Abramovitch, R.4
Amit, S.5
Kasem, S.6
-
84
-
-
35848970794
-
Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease
-
Massey DC, Parkes M. Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease. Autophagy. 2007;3(6):649-51.
-
(2007)
Autophagy
, vol.3
, Issue.6
, pp. 649-651
-
-
Massey, D.C.1
Parkes, M.2
-
85
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
-
Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature. 2008;456(7219):264-8.
-
(2008)
Nature
, vol.456
, Issue.7219
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
Uematsu, S.4
Yang, B.G.5
Satoh, T.6
-
86
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature. 2011;469(7329):221-5.
-
(2011)
Nature
, vol.469
, Issue.7329
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
87
-
-
79952184583
-
Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
-
Bulua AC, Simon A, Maddipati R, Pelletier M, Park H, Kim KY, et al. Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS). J Exp Med. 2011;208(3):519-33.
-
(2011)
J Exp Med
, vol.208
, Issue.3
, pp. 519-533
-
-
Bulua, A.C.1
Simon, A.2
Maddipati, R.3
Pelletier, M.4
Park, H.5
Kim, K.Y.6
-
88
-
-
19944432390
-
Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity
-
Walmsley SR, Print C, Farahi N, Peyssonnaux C, Johnson RS, Cramer T, et al. Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity. J Exp Med. 2005;201(1):105-15.
-
(2005)
J Exp Med
, vol.201
, Issue.1
, pp. 105-115
-
-
Walmsley, S.R.1
Print, C.2
Farahi, N.3
Peyssonnaux, C.4
Johnson, R.S.5
Cramer, T.6
-
89
-
-
79958056694
-
Inflammation-associated autophagy-related programmed necrotic death of human neutrophils characterized by organelle fusion events
-
Mihalache CC, Yousefi S, Conus S, Villiger PM, Schneider EM, Simon HU. Inflammation-associated autophagy-related programmed necrotic death of human neutrophils characterized by organelle fusion events. J Immunol. 2011;186(11):6532-42.
-
(2011)
J Immunol
, vol.186
, Issue.11
, pp. 6532-6542
-
-
Mihalache, C.C.1
Yousefi, S.2
Conus, S.3
Villiger, P.M.4
Schneider, E.M.5
Simon, H.U.6
-
90
-
-
82155192305
-
Hypoxia affects dendritic cell survival: role of the hypoxia-inducible factor-1alpha and lipopolysaccharide
-
Naldini A, Morena E, Pucci A, Miglietta D, Riboldi E, Sozzani S, et al. Hypoxia affects dendritic cell survival: role of the hypoxia-inducible factor-1alpha and lipopolysaccharide. J Cell Physiol. 2012;227(2):587-95.
-
(2012)
J Cell Physiol
, vol.227
, Issue.2
, pp. 587-595
-
-
Naldini, A.1
Morena, E.2
Pucci, A.3
Miglietta, D.4
Riboldi, E.5
Sozzani, S.6
-
91
-
-
34548700796
-
Unveiling the roles of autophagy in innate and adaptive immunity
-
Levine B, Deretic V. Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol. 2007;7(10):767-77.
-
(2007)
Nat Rev Immunol
, vol.7
, Issue.10
, pp. 767-777
-
-
Levine, B.1
Deretic, V.2
-
92
-
-
34447629523
-
Innate and adaptive immunity through autophagy
-
Schmid D, Munz C. Innate and adaptive immunity through autophagy. Immunity. 2007;27(1):11-21.
-
(2007)
Immunity
, vol.27
, Issue.1
, pp. 11-21
-
-
Schmid, D.1
Munz, C.2
-
93
-
-
33846461678
-
A critical role for the autophagy gene Atg5 in T cell survival and proliferation
-
Pua HH, Dzhagalov I, Chuck M, Mizushima N, He YW. A critical role for the autophagy gene Atg5 in T cell survival and proliferation. J Exp Med. 2007;204(1):25-31.
-
(2007)
J Exp Med
, vol.204
, Issue.1
, pp. 25-31
-
-
Pua, H.H.1
Dzhagalov, I.2
Chuck, M.3
Mizushima, N.4
He, Y.W.5
-
94
-
-
78650643194
-
Macroautophagy regulates energy metabolism during effector T cell activation
-
Hubbard VM, Valdor R, Patel B, Singh R, Cuervo AM, Macian F. Macroautophagy regulates energy metabolism during effector T cell activation. J Immunol. 2010;185(12):7349-57.
-
(2010)
J Immunol
, vol.185
, Issue.12
, pp. 7349-7357
-
-
Hubbard, V.M.1
Valdor, R.2
Patel, B.3
Singh, R.4
Cuervo, A.M.5
Macian, F.6
-
95
-
-
79955540204
-
Temporal regulation of intracellular organelle homeostasis in T lymphocytes by autophagy
-
Jia W, He YW. Temporal regulation of intracellular organelle homeostasis in T lymphocytes by autophagy. J Immunol. 2011;186(9):5313-22.
-
(2011)
J Immunol
, vol.186
, Issue.9
, pp. 5313-5322
-
-
Jia, W.1
He, Y.W.2
-
96
-
-
84908218156
-
Autophagy: an adaptive metabolic response to stress shaping the antitumor immunity
-
Viry E, Paggetti J, Baginska J, Mgrditchian T, Berchem G, Moussay E, et al. Autophagy: an adaptive metabolic response to stress shaping the antitumor immunity. Biochem Pharmacol. 2014;92(1):31-42.
-
(2014)
Biochem Pharmacol
, vol.92
, Issue.1
, pp. 31-42
-
-
Viry, E.1
Paggetti, J.2
Baginska, J.3
Mgrditchian, T.4
Berchem, G.5
Moussay, E.6
-
97
-
-
80053634368
-
The dynamic nature of autophagy in cancer
-
Kimmelman AC. The dynamic nature of autophagy in cancer. Genes Dev. 2011;25(19):1999-2010.
-
(2011)
Genes Dev
, vol.25
, Issue.19
, pp. 1999-2010
-
-
Kimmelman, A.C.1
-
98
-
-
84869147050
-
Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation
-
Wang RC, Wei Y, An Z, Zou Z, Xiao G, Bhagat G, et al. Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation. Science. 2012;338(6109):956-9.
-
(2012)
Science
, vol.338
, Issue.6109
, pp. 956-959
-
-
Wang, R.C.1
Wei, Y.2
An, Z.3
Zou, Z.4
Xiao, G.5
Bhagat, G.6
-
99
-
-
34547132328
-
Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3
-
Marino G, Salvador-Montoliu N, Fueyo A, Knecht E, Mizushima N, Lopez-Otin C. Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3. J Biol Chem. 2007;282(25):18573-83.
-
(2007)
J Biol Chem
, vol.282
, Issue.25
, pp. 18573-18583
-
-
Marino, G.1
Salvador-Montoliu, N.2
Fueyo, A.3
Knecht, E.4
Mizushima, N.5
Lopez-Otin, C.6
-
100
-
-
33745751085
-
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
-
Liang C, Feng P, Ku B, Dotan I, Canaani D, Oh BH, et al. Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol. 2006;8(7):688-99.
-
(2006)
Nat Cell Biol
, vol.8
, Issue.7
, pp. 688-699
-
-
Liang, C.1
Feng, P.2
Ku, B.3
Dotan, I.4
Canaani, D.5
Oh, B.H.6
-
101
-
-
34848899280
-
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
-
Takahashi Y, Coppola D, Matsushita N, Cualing HD, Sun M, Sato Y, et al. Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis. Nat Cell Biol. 2007;9(10):1142-51.
-
(2007)
Nat Cell Biol
, vol.9
, Issue.10
, pp. 1142-1151
-
-
Takahashi, Y.1
Coppola, D.2
Matsushita, N.3
Cualing, H.D.4
Sun, M.5
Sato, Y.6
-
102
-
-
79955377420
-
Autophagy-deficient mice develop multiple liver tumors
-
Takamura A, Komatsu M, Hara T, Sakamoto A, Kishi C, Waguri S, et al. Autophagy-deficient mice develop multiple liver tumors. Genes Dev. 2011;25(8):795-800.
-
(2011)
Genes Dev
, vol.25
, Issue.8
, pp. 795-800
-
-
Takamura, A.1
Komatsu, M.2
Hara, T.3
Sakamoto, A.4
Kishi, C.5
Waguri, S.6
-
103
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
-
Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, Lennerz JK, et al. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature. 2008;456(7219):259-63.
-
(2008)
Nature
, vol.456
, Issue.7219
, pp. 259-263
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
Miyoshi, H.4
Loh, J.5
Lennerz, J.K.6
-
104
-
-
61649114427
-
A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease
-
Cadwell K, Patel KK, Komatsu M, Virgin HW, Stappenbeck TS. A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease. Autophagy. 2009;5(2):250-2.
-
(2009)
Autophagy
, vol.5
, Issue.2
, pp. 250-252
-
-
Cadwell, K.1
Patel, K.K.2
Komatsu, M.3
Virgin, H.W.4
Stappenbeck, T.S.5
-
105
-
-
84875995650
-
Paradoxical role of autophagy in the dysplastic and tumor-forming stages of hepatocarcinoma development in rats
-
Sun K, Guo XL, Zhao QD, Jing YY, Kou XR, Xie XQ, et al. Paradoxical role of autophagy in the dysplastic and tumor-forming stages of hepatocarcinoma development in rats. Cell Death Dis. 2013;4:e501.
-
(2013)
Cell Death Dis
, vol.4
, pp. e501
-
-
Sun, K.1
Guo, X.L.2
Zhao, Q.D.3
Jing, Y.Y.4
Kou, X.R.5
Xie, X.Q.6
-
106
-
-
79955469013
-
Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis
-
Altman BJ, Jacobs SR, Mason EF, Michalek RD, MacIntyre AN, Coloff JL, et al. Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis. Oncogene. 2011;30(16):1855-67.
-
(2011)
Oncogene
, vol.30
, Issue.16
, pp. 1855-1867
-
-
Altman, B.J.1
Jacobs, S.R.2
Mason, E.F.3
Michalek, R.D.4
MacIntyre, A.N.5
Coloff, J.L.6
-
107
-
-
79952228407
-
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
-
Guo JY, Chen HY, Mathew R, Fan J, Strohecker AM, Karsli-Uzunbas G, et al. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev. 2011;25(5):460-70.
-
(2011)
Genes Dev
, vol.25
, Issue.5
, pp. 460-470
-
-
Guo, J.Y.1
Chen, H.Y.2
Mathew, R.3
Fan, J.4
Strohecker, A.M.5
Karsli-Uzunbas, G.6
-
108
-
-
79960401862
-
Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis
-
Wei H, Wei S, Gan B, Peng X, Zou W, Guan JL. Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis. Genes Dev. 2011;25(14):1510-27.
-
(2011)
Genes Dev
, vol.25
, Issue.14
, pp. 1510-1527
-
-
Wei, H.1
Wei, S.2
Gan, B.3
Peng, X.4
Zou, W.5
Guan, J.L.6
-
109
-
-
77953289524
-
Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model
-
Li J, Hou N, Faried A, Tsutsumi S, Kuwano H. Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model. Eur J Cancer. 2010;46(10):1900-9.
-
(2010)
Eur J Cancer
, vol.46
, Issue.10
, pp. 1900-1909
-
-
Li, J.1
Hou, N.2
Faried, A.3
Tsutsumi, S.4
Kuwano, H.5
-
110
-
-
79952244140
-
Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells
-
Liu D, Yang Y, Liu Q, Wang J. Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells. Med Oncol. 2011;28(1):105-11.
-
(2011)
Med Oncol
, vol.28
, Issue.1
, pp. 105-111
-
-
Liu, D.1
Yang, Y.2
Liu, Q.3
Wang, J.4
-
111
-
-
77951212660
-
Autophagy and metastasis: another double-edged sword
-
Kenific CM, Thorburn A, Debnath J. Autophagy and metastasis: another double-edged sword. Curr Opin Cell Biol. 2010;22(2):241-5.
-
(2010)
Curr Opin Cell Biol
, vol.22
, Issue.2
, pp. 241-245
-
-
Kenific, C.M.1
Thorburn, A.2
Debnath, J.3
-
112
-
-
34347404887
-
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis
-
Karantza-Wadsworth V, Patel S, Kravchuk O, Chen G, Mathew R, Jin S, et al. Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes Dev. 2007;21(13):1621-35.
-
(2007)
Genes Dev
, vol.21
, Issue.13
, pp. 1621-1635
-
-
Karantza-Wadsworth, V.1
Patel, S.2
Kravchuk, O.3
Chen, G.4
Mathew, R.5
Jin, S.6
-
113
-
-
79952728102
-
The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance
-
Mortensen M, Soilleux EJ, Djordjevic G, Tripp R, Lutteropp M, Sadighi-Akha E, et al. The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance. J Exp Med. 2011;208(3):455-67.
-
(2011)
J Exp Med
, vol.208
, Issue.3
, pp. 455-467
-
-
Mortensen, M.1
Soilleux, E.J.2
Djordjevic, G.3
Tripp, R.4
Lutteropp, M.5
Sadighi-Akha, E.6
-
114
-
-
84876893671
-
FIP200 is required for maintenance and differentiation of postnatal neural stem cells
-
Wang C, Liang CC, Bian ZC, Zhu Y, Guan JL. FIP200 is required for maintenance and differentiation of postnatal neural stem cells. Nat Neurosci. 2013;16(5):532-42.
-
(2013)
Nat Neurosci
, vol.16
, Issue.5
, pp. 532-542
-
-
Wang, C.1
Liang, C.C.2
Bian, Z.C.3
Zhu, Y.4
Guan, J.L.5
-
115
-
-
0037062934
-
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
-
Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature. 2002;418(6894):191-5.
-
(2002)
Nature
, vol.418
, Issue.6894
, pp. 191-195
-
-
Scaffidi, P.1
Misteli, T.2
Bianchi, M.E.3
-
116
-
-
78649704325
-
Autophagy and metabolism
-
Rabinowitz JD, White E. Autophagy and metabolism. Science. 2010;330(6009):1344-8.
-
(2010)
Science
, vol.330
, Issue.6009
, pp. 1344-1348
-
-
Rabinowitz, J.D.1
White, E.2
-
117
-
-
79961116194
-
A critical role for autophagy in pancreatic cancer
-
Yang S, Kimmelman AC. A critical role for autophagy in pancreatic cancer. Autophagy. 2011;7(8):912-3.
-
(2011)
Autophagy
, vol.7
, Issue.8
, pp. 912-913
-
-
Yang, S.1
Kimmelman, A.C.2
-
118
-
-
84879517225
-
One cell, multiple roles: contribution of mesenchymal stem cells to tumor development in tumor microenvironment
-
Yang X, Hou J, Han Z, Wang Y, Hao C, Wei L, et al. One cell, multiple roles: contribution of mesenchymal stem cells to tumor development in tumor microenvironment. Cell & bioscience. 2013;3(1):5.
-
(2013)
Cell & bioscience
, vol.3
, Issue.1
, pp. 5
-
-
Yang, X.1
Hou, J.2
Han, Z.3
Wang, Y.4
Hao, C.5
Wei, L.6
-
119
-
-
0036738149
-
Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins
-
Konopleva M, Konoplev S, Hu W, Zaritskey AY, Afanasiev BV, Andreeff M. Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins. Leukemia. 2002;16(9):1713-24.
-
(2002)
Leukemia
, vol.16
, Issue.9
, pp. 1713-1724
-
-
Konopleva, M.1
Konoplev, S.2
Hu, W.3
Zaritskey, A.Y.4
Afanasiev, B.V.5
Andreeff, M.6
-
120
-
-
34250788040
-
Bone marrow stromal cells prevent apoptosis of lymphoma cells by upregulation of anti-apoptotic proteins associated with activation of NF-kappaB (RelB/p52) in non-Hodgkin's lymphoma cells
-
Lwin T, Hazlehurst LA, Li Z, Dessureault S, Sotomayor E, Moscinski LC, et al. Bone marrow stromal cells prevent apoptosis of lymphoma cells by upregulation of anti-apoptotic proteins associated with activation of NF-kappaB (RelB/p52) in non-Hodgkin's lymphoma cells. Leukemia. 2007;21(7):1521-31.
-
(2007)
Leukemia
, vol.21
, Issue.7
, pp. 1521-1531
-
-
Lwin, T.1
Hazlehurst, L.A.2
Li, Z.3
Dessureault, S.4
Sotomayor, E.5
Moscinski, L.C.6
-
121
-
-
0038717067
-
Bone marrow stromal-derived soluble factors and direct cell contact contribute to de novo drug resistance of myeloma cells by distinct mechanisms
-
Nefedova Y, Landowski TH, Dalton WS. Bone marrow stromal-derived soluble factors and direct cell contact contribute to de novo drug resistance of myeloma cells by distinct mechanisms. Leukemia. 2003;17(6):1175-82.
-
(2003)
Leukemia
, vol.17
, Issue.6
, pp. 1175-1182
-
-
Nefedova, Y.1
Landowski, T.H.2
Dalton, W.S.3
-
122
-
-
33846255324
-
Human mesenchymal stem cells isolated from bone marrow and lymphoid organs support tumor B-cell growth: role of stromal cells in follicular lymphoma pathogenesis
-
Ame-Thomas P, Maby-El Hajjami H, Monvoisin C, Jean R, Monnier D, Caulet-Maugendre S, et al. Human mesenchymal stem cells isolated from bone marrow and lymphoid organs support tumor B-cell growth: role of stromal cells in follicular lymphoma pathogenesis. Blood. 2007;109(2):693-702.
-
(2007)
Blood
, vol.109
, Issue.2
, pp. 693-702
-
-
Ame-Thomas, P.1
Maby-El Hajjami, H.2
Monvoisin, C.3
Jean, R.4
Monnier, D.5
Caulet-Maugendre, S.6
-
123
-
-
79960046702
-
Activation of autophagy in mesenchymal stem cells provides tumor stromal support
-
Sanchez CG, Penfornis P, Oskowitz AZ, Boonjindasup AG, Cai DZ, Dhule SS, et al. Activation of autophagy in mesenchymal stem cells provides tumor stromal support. Carcinogenesis. 2011;32(7):964-72.
-
(2011)
Carcinogenesis
, vol.32
, Issue.7
, pp. 964-972
-
-
Sanchez, C.G.1
Penfornis, P.2
Oskowitz, A.Z.3
Boonjindasup, A.G.4
Cai, D.Z.5
Dhule, S.S.6
-
124
-
-
80052697287
-
The role of autophagy in cancer: therapeutic implications
-
Yang ZJ, Chee CE, Huang S, Sinicrope FA. The role of autophagy in cancer: therapeutic implications. Mol Cancer Ther. 2011;10(9):1533-41.
-
(2011)
Mol Cancer Ther
, vol.10
, Issue.9
, pp. 1533-1541
-
-
Yang, Z.J.1
Chee, C.E.2
Huang, S.3
Sinicrope, F.A.4
-
125
-
-
73449120372
-
Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review
-
Ruiz-Irastorza G, Ramos-Casals M, Brito-Zeron P, Khamashta MA. Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review. Ann Rheum Dis. 2010;69(1):20-8.
-
(2010)
Ann Rheum Dis
, vol.69
, Issue.1
, pp. 20-28
-
-
Ruiz-Irastorza, G.1
Ramos-Casals, M.2
Brito-Zeron, P.3
Khamashta, M.A.4
|