-
1
-
-
0036380377
-
A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology
-
T. Acker, and K.H. Plate A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology J Mol Med 80 2002 562 575
-
(2002)
J Mol Med
, vol.80
, pp. 562-575
-
-
Acker, T.1
Plate, K.H.2
-
2
-
-
0028035447
-
Regulation of cell proliferation under extreme and moderate hypoxia: The role of pyrimidine (deoxy)nucleotides
-
O. Amellem, M. Löffler, and E.O. Pettersen Regulation of cell proliferation under extreme and moderate hypoxia: the role of pyrimidine (deoxy)nucleotides Br. J. Cancer 70 1994 857 866
-
(1994)
Br. J. Cancer
, vol.70
, pp. 857-866
-
-
Amellem, O.1
Löffler, M.2
Pettersen, E.O.3
-
3
-
-
0032053823
-
The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
-
J.M. Brown, and A.J. Giaccia The unique physiology of solid tumors: opportunities (and problems) for cancer therapy Cancer Res. 58 1998 1408 1416
-
(1998)
Cancer Res.
, vol.58
, pp. 1408-1416
-
-
Brown, J.M.1
Giaccia, A.J.2
-
4
-
-
0035893396
-
Acute (cyclic) hypoxia enhances spontaneous metastasis of KHT murine tumors
-
R.A. Cairns, T. Kalliomaki, and R.P. Hill Acute (cyclic) hypoxia enhances spontaneous metastasis of KHT murine tumors Cancer Res 61 2001 8903 8908
-
(2001)
Cancer Res
, vol.61
, pp. 8903-8908
-
-
Cairns, R.A.1
Kalliomaki, T.2
Hill, R.P.3
-
5
-
-
0032842837
-
Hypoxia induces pivotal tumor angiogenesis control factors including p53, vascular endothelial growth factor and the NFκB-dependent inducible nitric oxide synthase and cyclooxygenase-2
-
V. Chiarugi, L. Magnelli, A. Chiarugi, and O. Gallo Hypoxia induces pivotal tumor angiogenesis control factors including p53, vascular endothelial growth factor and the NFκB-dependent inducible nitric oxide synthase and cyclooxygenase-2 J. Cancer Res. Clin. Oncol. 125 1999 525 528
-
(1999)
J. Cancer Res. Clin. Oncol.
, vol.125
, pp. 525-528
-
-
Chiarugi, V.1
Magnelli, L.2
Chiarugi, A.3
Gallo, O.4
-
6
-
-
0033808725
-
Oxygen regulation of gene expression: A study in opposites
-
C.T. D'Angio, and J.N. Finkelstein Oxygen regulation of gene expression: a study in opposites Mol Genet Metab 71 2000 371 380
-
(2000)
Mol Genet Metab
, vol.71
, pp. 371-380
-
-
D'Angio, C.T.1
Finkelstein, J.N.2
-
7
-
-
0037449777
-
Tyrosine phosphorylation of IκBα activates NF κb through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation
-
C. Fan, Q. Li, D. Ross, and J.F. Engelhardt Tyrosine phosphorylation of IκBα activates NF κB through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation J Biol Chem 278 2003 2072 2080
-
(2003)
J Biol Chem
, vol.278
, pp. 2072-2080
-
-
Fan, C.1
Li, Q.2
Ross, D.3
Engelhardt, J.F.4
-
8
-
-
0030067856
-
Hypoxic stress proteins: Survival of the fittest
-
A.J. Giaccia Hypoxic stress proteins: survival of the fittest Semin. Radiat. Oncol. 6 1996 46 58
-
(1996)
Semin. Radiat. Oncol.
, vol.6
, pp. 46-58
-
-
Giaccia, A.J.1
-
9
-
-
0030025773
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
-
T.G. Graeber, C. Osmanian, T. Jacks, D.E. Housman, C.J. Koch, and S.W. Lowe Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours Nature 379 1996 88 91
-
(1996)
Nature
, vol.379
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
Housman, D.E.4
Koch, C.J.5
Lowe, S.W.6
-
10
-
-
0002052681
-
Significance of hemoglobin concentration for treatment outcome
-
M. Molls P. Vaupel
-
C. Grau, and J. Overgaard Significance of hemoglobin concentration for treatment outcome M. Molls P. Vaupel Blood perfusion and microenvironment of human tumors 2000 101 112 Berlin, Heidelberg, New York: Springer
-
(2000)
Blood Perfusion and Microenvironment of Human Tumors
, pp. 101-112
-
-
Grau, C.1
Overgaard, J.2
-
11
-
-
0036359548
-
Hypoxia--a key regulatory factor in tumour growth
-
A.L. Harris Hypoxia--a key regulatory factor in tumour growth Nat Rev Cancer 2 2002 38 47
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
12
-
-
0035925098
-
Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
-
M. Höckel, and P. Vaupel Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects J Natl Cancer Inst 93 2001 266 276
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 266-276
-
-
Höckel, M.1
Vaupel, P.2
-
13
-
-
0029775242
-
Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
-
M. Höckel, K. Schlenger, B. Aral, M. Mitze, U. Schäffer, and P. Vaupel Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix Cancer Res. 56 1996 4509 4515
-
(1996)
Cancer Res.
, vol.56
, pp. 4509-4515
-
-
Höckel, M.1
Schlenger, K.2
Aral, B.3
Mitze, M.4
Schäffer, U.5
Vaupel, P.6
-
15
-
-
0028268629
-
Hypoxia causes the activation of nuclear factor κb through the phosphorylation of IκBα on tyrosine residues
-
A. Koong, E. Chen, and A. Giaccia Hypoxia causes the activation of nuclear factor κB through the phosphorylation of IκBα on tyrosine residues Cancer Res. 54 1994 1425 1430
-
(1994)
Cancer Res.
, vol.54
, pp. 1425-1430
-
-
Koong, A.1
Chen, E.2
Giaccia, A.3
-
16
-
-
0036837864
-
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha
-
C. Koumenis, C. Naczki, M. Koritzinsky, S. Rastani, A. Diehl, and N. Sonenberg Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha Mol Cell Biol 22 2002 7405 7416
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7405-7416
-
-
Koumenis, C.1
Naczki, C.2
Koritzinsky, M.3
Rastani, S.4
Diehl, A.5
Sonenberg, N.6
-
17
-
-
0037374289
-
Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1
-
B. Krishnamachary, S. Berg-Dixon, B. Kelly, F. Agani, D. Feldser, and G. Ferreira Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1 Cancer Res 63 2003 1138 1143
-
(2003)
Cancer Res
, vol.63
, pp. 1138-1143
-
-
Krishnamachary, B.1
Berg-Dixon, S.2
Kelly, B.3
Agani, F.4
Feldser, D.5
Ferreira, G.6
-
18
-
-
0032771749
-
Molecular analysis of selected cell cycle regulatory proteins during aerobic and hypoxic maintenance of human ovarian carcinoma cells
-
A. Krtolica, N.A. Krucher, and J.W. Ludlow Molecular analysis of selected cell cycle regulatory proteins during aerobic and hypoxic maintenance of human ovarian carcinoma cells Br. J. Cancer 80 1999 1875 1883
-
(1999)
Br. J. Cancer
, vol.80
, pp. 1875-1883
-
-
Krtolica, A.1
Krucher, N.A.2
Ludlow, J.W.3
-
19
-
-
0036210708
-
The response of c-Jun/AP-1 to chronic hypoxia is hypoxia-inducible factor 1α dependent
-
K.R. Laderoute, J.M. Calaoagan, C. Gustafson-Brown, A.M. Knapp, G.-C. Li, and H.L. Mendonca The response of c-Jun/AP-1 to chronic hypoxia is hypoxia-inducible factor 1α dependent Mol Cell Biol 22 2002 2515 2523
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2515-2523
-
-
Laderoute, K.R.1
Calaoagan, J.M.2
Gustafson-Brown, C.3
Knapp, A.M.4
Li, G.-C.5
Mendonca, H.L.6
-
20
-
-
0035812284
-
Transcriptional response to hypoxia in human tumors
-
A. Lal, H. Peters, B. St Croix, Z.A. Haroon, M.W. Dewhirst, and R.L. Strausberg Transcriptional response to hypoxia in human tumors J Natl Cancer Inst 93 2001 1337 1343
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1337-1343
-
-
Lal, A.1
Peters, H.2
St Croix, B.3
Haroon, Z.A.4
Dewhirst, M.W.5
Strausberg, R.L.6
-
21
-
-
18544384240
-
Hypoxia enhances the expression of autocrine motility factor and the motility of human pancreatic cancer cells
-
H. Niizeki, M. Kobayashi, I. Horiuchi, N. Akakura, J. Chen, and J. Wang Hypoxia enhances the expression of autocrine motility factor and the motility of human pancreatic cancer cells Br J Cancer 86 2002 1914 1919
-
(2002)
Br J Cancer
, vol.86
, pp. 1914-1919
-
-
Niizeki, H.1
Kobayashi, M.2
Horiuchi, I.3
Akakura, N.4
Chen, J.5
Wang, J.6
-
22
-
-
0037478437
-
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
-
S. Pennacchietti, P. Michieli, M. Galluzzo, M. Mazzone, S. Giordano, and P.M. Comoglio Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene Cancer Cell 3 2003 347 361
-
(2003)
Cancer Cell
, vol.3
, pp. 347-361
-
-
Pennacchietti, S.1
Michieli, P.2
Galluzzo, M.3
Mazzone, M.4
Giordano, S.5
Comoglio, P.M.6
-
23
-
-
0028841622
-
The genomic response of tumor cells to hypoxia and reoxygenation. Differential activation of transcription factors AP-1 and NF-kB
-
R.A. Rupec, and P.A. Baeuerle The genomic response of tumor cells to hypoxia and reoxygenation. Differential activation of transcription factors AP-1 and NF-kB Eur. J. Biochem. 234 1995 632 640
-
(1995)
Eur. J. Biochem.
, vol.234
, pp. 632-640
-
-
Rupec, R.A.1
Baeuerle, P.A.2
-
24
-
-
0034901463
-
Hypoxia-inducible factor 1: Oxygen homeostasis and disease pathophysiology
-
G.L. Semenza Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology Trends Mol Med 7 2001 345 350
-
(2001)
Trends Mol Med
, vol.7
, pp. 345-350
-
-
Semenza, G.L.1
-
25
-
-
0036216692
-
HIF-1 and tumor progression: Pathophysiology and therapeutics
-
G.L. Semenza HIF-1 and tumor progression: pathophysiology and therapeutics Trends Mol Med 8 2002 S62 S67
-
(2002)
Trends Mol Med
, vol.8
-
-
Semenza, G.L.1
-
26
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
G.L. Semenza Targeting HIF-1 for cancer therapy Nat Rev Cancer 3 2003 721 732
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
27
-
-
0028950645
-
Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL
-
S. Shimizu, Y. Eguchi, H. Kosaka, W. Kamiike, H. Matsuda, and Y. Tsujimoto Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL Nature 374 1995 811 813
-
(1995)
Nature
, vol.374
, pp. 811-813
-
-
Shimizu, S.1
Eguchi, Y.2
Kosaka, H.3
Kamiike, W.4
Matsuda, H.5
Tsujimoto, Y.6
-
28
-
-
0033515883
-
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition
-
M.S. Soengas, R.M. Alarcon, H. Yoshida, A.J. Giaccia, R. Hakem, and T.W. Mak Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition Science 284 1999 156 159
-
(1999)
Science
, vol.284
, pp. 156-159
-
-
Soengas, M.S.1
Alarcon, R.M.2
Yoshida, H.3
Giaccia, A.J.4
Hakem, R.5
Mak, T.W.6
-
29
-
-
0033914534
-
A pathway of neuronal apoptosis induced by hypoxia/reoxygenation: Roles of nuclear factor-κB and Bcl-2
-
M. Tamatani, N. Mitsuda, H. Matsuzaki, H. Okado, S. Miyake, and M.P. Vitek A pathway of neuronal apoptosis induced by hypoxia/reoxygenation: roles of nuclear factor-κB and Bcl-2 J Neurochem 75 2000 683 693
-
(2000)
J Neurochem
, vol.75
, pp. 683-693
-
-
Tamatani, M.1
Mitsuda, N.2
Matsuzaki, H.3
Okado, H.4
Miyake, S.5
Vitek, M.P.6
-
30
-
-
0038350531
-
Impact of haemoglobin levels on the outcome of cancers treated with chemotherapy
-
S.-P. Van Belle, and V. Cocquyt Impact of haemoglobin levels on the outcome of cancers treated with chemotherapy Crit Rev Oncol/Hematol 47 2003 1 11
-
(2003)
Crit Rev Oncol/Hematol
, vol.47
, pp. 1-11
-
-
Van Belle, S.-P.1
Cocquyt, V.2
-
32
-
-
0024408986
-
Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
-
P. Vaupel, F. Kallinowski, and P. Okunieff Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review Cancer Res. 49 1989 6449 6465
-
(1989)
Cancer Res.
, vol.49
, pp. 6449-6465
-
-
Vaupel, P.1
Kallinowski, F.2
Okunieff, P.3
-
33
-
-
0035677961
-
Treatment resistance of solid tumors: Role of hypoxia and anemia
-
P. Vaupel, O. Thews, and M. Hoeckel Treatment resistance of solid tumors: role of hypoxia and anemia Med Oncol 18 2001 243 259
-
(2001)
Med Oncol
, vol.18
, pp. 243-259
-
-
Vaupel, P.1
Thews, O.2
Hoeckel, M.3
-
34
-
-
1642565876
-
Tumor hypoxia and malignant progression
-
P. Vaupel, A. Mayer, and M. Höckel Tumor hypoxia and malignant progression Methods Enzymol 381 2004 335 354
-
(2004)
Methods Enzymol
, vol.381
, pp. 335-354
-
-
Vaupel, P.1
Mayer, A.2
Höckel, M.3
|