Regulation of HMGB1 release by autophagy

Autophagy

Volumn 5, Issue 2, 2009, Pages 247-249

  Thorburn, Jacqueline ^b   Frankel, Arthur E ^b   Thorburn, Andrew ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

Apoptosis; Autophagy; Diphtheria toxin; Glioblastoma; HMGB1

Indexed keywords

CASPASE; DIPHTHERIA TOXIN; EPIDERMAL GROWTH FACTOR; HIGH MOBILITY GROUP B1 PROTEIN;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; ENZYME ACTIVATION; FRAGMENTATION REACTION; GLIOBLASTOMA; HUMAN; IMMUNE RESPONSE; PROTEIN SECRETION;

EID: 61649086413     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.5.2.7552     Document Type: Article

References (22)

1. García-Escudero V, Gargini R. Autophagy induction as an efficient strategy to eradicate tumors. Autophagy 2008; 4:923-5.
2. Lin MH, Liu SY, Liu YC. Autophagy induction by a natural ingredient of areca nut. Autophagy 2008; 4:967-8.
3. Turcotte S, Sutphin PD, Giaccia AJ. Targeted therapy for the loss of von Hippel-Lindau in renal cell carcinoma: a novel molecule that induces autophagic cell death. Autophagy 2008; 4:944-6.
4. Roca H, Varsos ZS, Mizutani K, Pienta KJ. CCL2, survivin and autophagy: new links with implications in human cancer. Autophagy 2008; 4:969-71.
5. Hou W, Han J, Lu C, Goldstein LA, Rabinowich H. Enhancement of tumor-TRAIL susceptibility by modulation of autophagy. Autophagy 2008; 4:940-3.
6. Park MA, Zhang G, Norris J, Hylemon PB, Fisher PB, Grant S, Dent P. Regulation of autophagy by ceramide-CD95-PERK signaling. Autophagy 2008; 4:929-31.
7. Kroemer G, Levine B. Autophagic cell death: the story of a misnomer. Nat Rev Mol Cell Biol 2008; 9:1004-10.
8. Hippert MM, O'Toole PS, Thorburn A. Autophagy and cancer: good bad or both? Cancer Res 2006; 66:9349-51.
9. Amaravadi RK, Thompson CB. The roles of therapy-induced autophagy and necrosis in cancer treatment. Clin Cancer Res 2007; 13:7271-9.
10. Høyer-Hansen M, Jäättelä M. Autophagy: an emerging target for cancer therapy. Autophagy 2008; 4:574-80.
11. Thorburn J, Horita H, Redzic J, Hansen K, Frankel AE, Thorburn A. Autophagy regulates selective HMGB1 release in tumor cells that are destined to die. Cell Death Differ 2009; 16:175-83.
12. Pastan I, Hassan R, Fitzgerald DJ, Kreitman RJ. Immunotoxin therapy of cancer. Nat Rev Cancer 2006; 6:559-65.
13. Thorburn A, Thorburn J, Frankel AE. Induction of apoptosis by tumor cell-targeted toxins. Apoptosis 2004; 9:19-25.
14. Horita H, Frankel AE, Thorburn A. Acute myeloid leukemia-targeted toxins kill tumor cells by cell type-specific mechanisms and synergize with TRAIL to allow manipulation of the extent and mechanism of tumor cell death. Leukemia 2008; 22:652-5.
15. Kimura S, Noda T, Yoshimori T. Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy 2007; 3:452-60.
16. Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Overvatn A, Bjorkoy G, Johansen T. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 2007; 282:24131-45.
17. Mercer CA, Kaliappan A, Dennis PB. Macroautophagy-dependent, intralysosomal cleavage of a betaine homocysteine methyltransferase fusion protein requires stable multimerization. Autophagy 2008; 4:185-94.
18. Thorburn A. Studying autophagy's relationship to cell death. Autophagy 2008; 4:391-4.
19. Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 2002; 418:191-5.
20. Kazama H, Ricci JE, Herndon JM, Hoppe G, Green DR, Ferguson TA. Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein. Immunity 2008; 29:21-32.
21. Apetoh L, Ghiringhelli F, Tesniere A, Obeid M, Ortiz C, Criollo A, Mignot G, Maiuri MC, Ullrich E, Saulnier P, Yang H, Amigorena S, Ryffel B, Barrat FJ, Saftig P, Levi F, Lidereau R, Nogues C, Mira JP, Chompret A, Joulin V, Clavel-Chapelon F, Bourhis J, Andre F, Delaloge S, Tursz T, Kroemer G, Zitvogel L. Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med 2007; 13:1050-9.
22. Zitvogel L, Apetoh L, Ghiringhelli F, Kroemer G. Immunological aspects of cancer chemotherapy. Nat Rev Immunol 2008; 8:59-73.