Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments

Cancer Research

Volumn 72, Issue 16, 2012, Pages 3938-3947

  Wojtkowiak, Jonathan W ^a   Rothberg, Jennifer M ^d   Kumar, Virendra ^a   Schramm, Karla J ^a   Haller, Edward ^b   Proemsey, Joshua B ^a   Lloyd, Mark C ^a   Sloane, Bonnie F ^c,d   Gillies, Robert J ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; AUTOPHAGY PROTEIN 5; BICARBONATE; CELL PROTEIN; PROTEIN BNIP3; PROTEIN LC3; PROTEIN LC3 II; UNCLASSIFIED DRUG;

ACIDOSIS; ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATG5 GENE; AUTOPHAGY; BNIP3 GENE; BREAST CARCINOMA; CANCER CELL CULTURE; CELL PH; CELL PROLIFERATION; CELL STIMULATION; CELL SURVIVAL; CELL VACUOLE; CONTROLLED STUDY; CYTOPLASM; DRUG SENSITIVITY; FEMALE; G1 PHASE CELL CYCLE CHECKPOINT; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR MICROENVIRONMENT;

ACIDOSIS; ANIMALS; AUTOPHAGY; BREAST NEOPLASMS; CELL HYPOXIA; CELL LINE, TUMOR; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; MICE; MICE, NUDE; MICROSCOPY, ELECTRON, TRANSMISSION; PANCREATIC NEOPLASMS; TUMOR MICROENVIRONMENT;

EID: 84865147552     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-3881     Document Type: Article

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