Autophagy is a protective mechanism for human melanoma cells under acidic stress

Journal of Biological Chemistry

Volumn 287, Issue 36, 2012, Pages 30664-30676

  Marino, Maria Lucia ^a   Pellegrini, Paola ^b   Di Lernia, Giuseppe ^b   Djavaheri Mergny, Mojgan ^c   Brnjic, Slavica ^b   Zhang, Xiaonan ^b   Hägg, Maria ^b   Linder, Stig ^b   Fais, Stefano ^a   Codogno, Patrice ^d   De Milito, Angelo ^a,b  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b KAROLINSKA INSTITUTE   (Sweden)

^c INSTITUT BERGONIÉ   (France)

^d INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC CONDITIONS; ACIDIC ENVIRONMENT; ADAPTATION MECHANISM; AMP-ACTIVATED PROTEIN KINASE; ATP CONTENT; AUTOPHAGY; BAFILOMYCIN; CANCER CELLS; CATABOLIC PATHWAY; CULTURE CONDITIONS; IMMUNOBLOT ANALYSIS; LYSOSOMAL DEGRADATION; MAMMALIAN TARGET; MELANOMA CELLS; METABOLIC STRESS; OXIDATIVE PHOSPHORYLATION; PH CONDITION; PH REGULATION; SIGNALING PATHWAYS; SOLID TUMORS; STRESS-INDUCED; THERAPEUTIC STRATEGY; THERAPEUTIC TARGETS; TUMOR PROGRESSIONS;

AMINO ACIDS; BIOELECTRIC POTENTIALS; CELL CULTURE; CHEMOTHERAPY; DEGRADATION; DERMATOLOGY; GENES; GLUCOSE; METABOLISM; ONCOLOGY; PATHOLOGY; PH; PHOSPHORYLATION; TUMORS;

CELLS;

ADENOSINE TRIPHOSPHATE; BAFILOMYCIN A1; CELL PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN LC3 II; S6 KINASE; UNCLASSIFIED DRUG;

ACIDIFICATION; ACIDITY; ADAPTATION; AMINO ACID TRANSPORT; ARTICLE; ATG5 GENE; AUTOPHAGY; CELL SURVIVAL; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE; GENE SILENCING; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; MELANOMA CELL; NUTRIENT UPTAKE; PH; PRIORITY JOURNAL;

AMP-ACTIVATED PROTEIN KINASES; AUTOPHAGY; CELL HYPOXIA; CELL LINE, TUMOR; HUMANS; HYDROGEN-ION CONCENTRATION; LYSOSOMES; MELANOMA; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; PHOSPHORYLATION; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; STRESS, PHYSIOLOGICAL; TOR SERINE-THREONINE KINASES;

MAMMALIA;

EID: 84865800743     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.339127     Document Type: Article

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