메뉴 건너뛰기




Volumn 213, Issue C, 2014, Pages 279-316

Epigenetic mechanisms in epilepsy

Author keywords

Chromatin remodeling; DNA methylation; Epileptic encephalopathy; Gene regulation; Genetic epilepsy; Hippocampus; Histone code; Metabolism; Noncoding RNA; Temporal lobe epilepsy

Indexed keywords

ANTIARRHYTHMIC AGENT; ANTIHYPERTENSIVE AGENT; ANTISENSE OLIGONUCLEOTIDE; DNA; LONG UNTRANSLATED RNA;

EID: 84924987118     PISSN: 00796123     EISSN: 18757855     Source Type: Book Series    
DOI: 10.1016/B978-0-444-63326-2.00014-4     Document Type: Chapter
Times cited : (42)

References (209)
  • 1
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • Amir R.E., Van Den Veyver I.B., Wan M., Tran C.Q., Francke U., Zoghbi H.Y. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet. 1999, 23:185-188.
    • (1999) Nat. Genet. , vol.23 , pp. 185-188
    • Amir, R.E.1    Van Den Veyver, I.B.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 3
    • 78649972918 scopus 로고    scopus 로고
    • Homocysteine potentiates seizures and cell loss induced by pilocarpine treatment
    • Baldelli E., Leo G., Andreoli N., Fuxe K., Biagini G., Agnati L.F. Homocysteine potentiates seizures and cell loss induced by pilocarpine treatment. Neuromol. Med. 2010, 12:248-259.
    • (2010) Neuromol. Med. , vol.12 , pp. 248-259
    • Baldelli, E.1    Leo, G.2    Andreoli, N.3    Fuxe, K.4    Biagini, G.5    Agnati, L.F.6
  • 9
    • 84875129831 scopus 로고    scopus 로고
    • DNA methylation dynamics in health and disease
    • Bergman Y., Cedar H. DNA methylation dynamics in health and disease. Nat. Struct. Mol. Biol. 2013, 20:274-281.
    • (2013) Nat. Struct. Mol. Biol. , vol.20 , pp. 274-281
    • Bergman, Y.1    Cedar, H.2
  • 10
    • 0034799972 scopus 로고    scopus 로고
    • Genetics of the epilepsies
    • Berkovic S.F., Scheffer I.E. Genetics of the epilepsies. Epilepsia 2001, 42(Suppl. 5):16-23.
    • (2001) Epilepsia , vol.42 , pp. 16-23
    • Berkovic, S.F.1    Scheffer, I.E.2
  • 13
    • 0033753779 scopus 로고    scopus 로고
    • The DNA methyltransferases of mammals
    • Bestor T.H. The DNA methyltransferases of mammals. Hum. Mol. Genet. 2000, 9:2395-2402.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 2395-2402
    • Bestor, T.H.1
  • 14
    • 33646893456 scopus 로고    scopus 로고
    • Molecular genetics of Rett syndrome: when DNA methylation goes unrecognized
    • Bienvenu T., Chelly J. Molecular genetics of Rett syndrome: when DNA methylation goes unrecognized. Nat. Rev. Genet. 2006, 7:415-426.
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 415-426
    • Bienvenu, T.1    Chelly, J.2
  • 16
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A. DNA methylation patterns and epigenetic memory. Genes Dev. 2002, 16:6-21.
    • (2002) Genes Dev. , vol.16 , pp. 6-21
    • Bird, A.1
  • 17
    • 39149122180 scopus 로고    scopus 로고
    • The adenosine kinase hypothesis of epileptogenesis
    • Boison D. The adenosine kinase hypothesis of epileptogenesis. Prog. Neurobiol. 2008, 84:249-262.
    • (2008) Prog. Neurobiol. , vol.84 , pp. 249-262
    • Boison, D.1
  • 23
    • 84868593544 scopus 로고    scopus 로고
    • Kinetic analysis of iron-dependent histone demethylases: α-ketoglutarate substrate inhibition and potential relevance to the regulation of histone demethylation in cancer cells
    • Cascella B., Mirica L.M. Kinetic analysis of iron-dependent histone demethylases: α-ketoglutarate substrate inhibition and potential relevance to the regulation of histone demethylation in cancer cells. Biochemistry 2012, 51:8699-8701.
    • (2012) Biochemistry , vol.51 , pp. 8699-8701
    • Cascella, B.1    Mirica, L.M.2
  • 25
    • 79960117245 scopus 로고    scopus 로고
    • Hypothesis: environmental regulation of 5-hydroxymethylcytosine by oxidative stress
    • Chia N., Wang L., Lu X., Senut M.C., Brenner C., Ruden D.M. Hypothesis: environmental regulation of 5-hydroxymethylcytosine by oxidative stress. Epigenetics 2011, 6:853-856.
    • (2011) Epigenetics , vol.6 , pp. 853-856
    • Chia, N.1    Wang, L.2    Lu, X.3    Senut, M.C.4    Brenner, C.5    Ruden, D.M.6
  • 28
    • 84926361183 scopus 로고    scopus 로고
    • Neuroinflammation on the epigenetics of neural stem cells
    • InTech Europe, Rijeka, Croatia, D.L. Bonfanti (Ed.)
    • Das N.D., Chai Y.G. Neuroinflammation on the epigenetics of neural stem cells. Neural Stem Cells-New Perspectives 2013, InTech Europe, Rijeka, Croatia. D.L. Bonfanti (Ed.).
    • (2013) Neural Stem Cells-New Perspectives
    • Das, N.D.1    Chai, Y.G.2
  • 29
    • 84878505755 scopus 로고    scopus 로고
    • Functional analysis of histone demethylase Jmjd2b on lipopolysaccharide-treated murine neural stem cells (NSCs)
    • Das N.D., Choi M.R., et al. Functional analysis of histone demethylase Jmjd2b on lipopolysaccharide-treated murine neural stem cells (NSCs). Neurotox. Res. 2013, 23(2):154-165.
    • (2013) Neurotox. Res. , vol.23 , Issue.2 , pp. 154-165
    • Das, N.D.1    Choi, M.R.2
  • 31
    • 33646869229 scopus 로고    scopus 로고
    • Chromatin remodelling in mammalian differentiation: lessons from ATP-dependent remodellers
    • De La Serna I.L., Ohkawa Y., Imbalzano A.N. Chromatin remodelling in mammalian differentiation: lessons from ATP-dependent remodellers. Nat. Rev. Genet. 2006, 7:461-473.
    • (2006) Nat. Rev. Genet. , vol.7 , pp. 461-473
    • De La Serna, I.L.1    Ohkawa, Y.2    Imbalzano, A.N.3
  • 33
    • 59749089928 scopus 로고    scopus 로고
    • MiRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex
    • De Pietri Tonelli D., Pulvers J.N., Haffner C., Murchison E.P., Hannon G.J., Huttner W.B. miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex. Development 2008, 135:3911-3921.
    • (2008) Development , vol.135 , pp. 3911-3921
    • De Pietri Tonelli, D.1    Pulvers, J.N.2    Haffner, C.3    Murchison, E.P.4    Hannon, G.J.5    Huttner, W.B.6
  • 34
    • 79956330964 scopus 로고    scopus 로고
    • CpG islands and the regulation of transcription
    • Deaton A.M., Bird A. CpG islands and the regulation of transcription. Genes Dev. 2011, 25:1010-1022.
    • (2011) Genes Dev. , vol.25 , pp. 1010-1022
    • Deaton, A.M.1    Bird, A.2
  • 35
    • 79959829510 scopus 로고    scopus 로고
    • Histone arginine methylation
    • Di Lorenzo A., Bedford M.T. Histone arginine methylation. FEBS Lett. 2011, 585:2024-2031.
    • (2011) FEBS Lett. , vol.585 , pp. 2024-2031
    • Di Lorenzo, A.1    Bedford, M.T.2
  • 36
    • 77953429462 scopus 로고    scopus 로고
    • Brain function and chromatin plasticity
    • Dulac C. Brain function and chromatin plasticity. Nature 2010, 465:728-735.
    • (2010) Nature , vol.465 , pp. 728-735
    • Dulac, C.1
  • 39
    • 83455178102 scopus 로고    scopus 로고
    • Screening for compounds that modulate epigenetic regulation of the transcriptome: an overview
    • Eglen R.M., Reisine T. Screening for compounds that modulate epigenetic regulation of the transcriptome: an overview. J. Biomol. Screen. 2011, 16:1137-1152.
    • (2011) J. Biomol. Screen. , vol.16 , pp. 1137-1152
    • Eglen, R.M.1    Reisine, T.2
  • 40
    • 0037444461 scopus 로고    scopus 로고
    • Overlapping microarray profiles of dentate gyrus gene expression during development- and epilepsy-associated neurogenesis and axon outgrowth
    • Elliott R.C., Miles M.F., Lowenstein D.H. Overlapping microarray profiles of dentate gyrus gene expression during development- and epilepsy-associated neurogenesis and axon outgrowth. J. Neurosci. 2003, 23:2218-2227.
    • (2003) J. Neurosci. , vol.23 , pp. 2218-2227
    • Elliott, R.C.1    Miles, M.F.2    Lowenstein, D.H.3
  • 41
    • 81355142141 scopus 로고    scopus 로고
    • Non-coding RNAs in human disease
    • Esteller M. Non-coding RNAs in human disease. Nat. Rev. Genet. 2011, 12:861-874.
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 861-874
    • Esteller, M.1
  • 44
    • 84890559595 scopus 로고    scopus 로고
    • Long non-coding RNAs: new players in cell differentiation and development
    • Fatica A., Bozzoni I. Long non-coding RNAs: new players in cell differentiation and development. Nat. Rev. Genet. 2014, 15:7-21.
    • (2014) Nat. Rev. Genet. , vol.15 , pp. 7-21
    • Fatica, A.1    Bozzoni, I.2
  • 45
    • 34247469843 scopus 로고    scopus 로고
    • Epigenetic regulation of neural gene expression and neuronal function
    • Feng J., Fouse S., Fan G. Epigenetic regulation of neural gene expression and neuronal function. Pediatr. Res. 2007, 61:58R-63R.
    • (2007) Pediatr. Res. , vol.61 , pp. 58R-63R
    • Feng, J.1    Fouse, S.2    Fan, G.3
  • 46
    • 77950187447 scopus 로고    scopus 로고
    • Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
    • Feng J., Zhou Y., Campbell S.L., Le T., Li E., Sweatt J.D., Silva A.J., Fan G. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat. Neurosci. 2010, 13:423-430.
    • (2010) Nat. Neurosci. , vol.13 , pp. 423-430
    • Feng, J.1    Zhou, Y.2    Campbell, S.L.3    Le, T.4    Li, E.5    Sweatt, J.D.6    Silva, A.J.7    Fan, G.8
  • 47
    • 34248523169 scopus 로고    scopus 로고
    • Recovery of learning and memory is associated with chromatin remodelling
    • Fischer A., Sananbenesi F., Wang X., Dobbin M., Tsai L.H. Recovery of learning and memory is associated with chromatin remodelling. Nature 2007, 447:178-182.
    • (2007) Nature , vol.447 , pp. 178-182
    • Fischer, A.1    Sananbenesi, F.2    Wang, X.3    Dobbin, M.4    Tsai, L.H.5
  • 48
    • 58049198236 scopus 로고    scopus 로고
    • Talk is cheap-cross-talk in establishment, maintenance, and readout of chromatin modifications
    • Fischle W. Talk is cheap-cross-talk in establishment, maintenance, and readout of chromatin modifications. Genes Dev. 2008, 22:3375-3382.
    • (2008) Genes Dev. , vol.22 , pp. 3375-3382
    • Fischle, W.1
  • 49
    • 84864301890 scopus 로고    scopus 로고
    • The role of methyl-binding proteins in chromatin organization and epigenome maintenance
    • Fournier A., Sasai N., Nakao M., Defossez P.A. The role of methyl-binding proteins in chromatin organization and epigenome maintenance. Brief. Funct. Genomics 2012, 11:251-264.
    • (2012) Brief. Funct. Genomics , vol.11 , pp. 251-264
    • Fournier, A.1    Sasai, N.2    Nakao, M.3    Defossez, P.A.4
  • 51
    • 33847398443 scopus 로고    scopus 로고
    • Alpha thalassaemia-mental retardation, X linked
    • Gibbons R. Alpha thalassaemia-mental retardation, X linked. Orphanet J. Rare Dis. 2006, 1:15.
    • (2006) Orphanet J. Rare Dis. , vol.1 , pp. 15
    • Gibbons, R.1
  • 52
    • 15744401773 scopus 로고    scopus 로고
    • Eukaryotic cytosine methyltransferases
    • Goll M.G., Bestor T.H. Eukaryotic cytosine methyltransferases. Annu. Rev. Biochem. 2005, 74:481-514.
    • (2005) Annu. Rev. Biochem. , vol.74 , pp. 481-514
    • Goll, M.G.1    Bestor, T.H.2
  • 53
    • 84860388901 scopus 로고    scopus 로고
    • Active DNA demethylation by oxidation and repair
    • Gong Z., Zhu J.K. Active DNA demethylation by oxidation and repair. Cell Res. 2011, 21:1649-1651.
    • (2011) Cell Res. , vol.21 , pp. 1649-1651
    • Gong, Z.1    Zhu, J.K.2
  • 54
    • 33751099302 scopus 로고    scopus 로고
    • Potential new antiepileptogenic targets indicated by microarray analysis in a rat model for temporal lobe epilepsy
    • Gorter J.A., Van Vliet E.A., Aronica E., Breit T., Rauwerda H., Lopes Da Silva F.H., Wadman W.J. Potential new antiepileptogenic targets indicated by microarray analysis in a rat model for temporal lobe epilepsy. J. Neurosci. 2006, 26:11083-11110.
    • (2006) J. Neurosci. , vol.26 , pp. 11083-11110
    • Gorter, J.A.1    Van Vliet, E.A.2    Aronica, E.3    Breit, T.4    Rauwerda, H.5    Lopes Da Silva, F.H.6    Wadman, W.J.7
  • 56
    • 0842284006 scopus 로고    scopus 로고
    • Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis
    • Gouder N., Scheurer L., Fritschy J.M., Boison D. Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis. J. Neurosci. 2004, 24:692-701.
    • (2004) J. Neurosci. , vol.24 , pp. 692-701
    • Gouder, N.1    Scheurer, L.2    Fritschy, J.M.3    Boison, D.4
  • 57
    • 0035933337 scopus 로고    scopus 로고
    • Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpG [correction of non-CpA] sites
    • Gowher H., Jeltsch A. Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpG [correction of non-CpA] sites. J. Mol. Biol. 2001, 309:1201-1208.
    • (2001) J. Mol. Biol. , vol.309 , pp. 1201-1208
    • Gowher, H.1    Jeltsch, A.2
  • 58
    • 0028905178 scopus 로고
    • Seven novel mutations in the methylenetetrahydrofolate reductase gene and genotype/phenotype correlations in severe methylenetetrahydrofolate reductase deficiency
    • Goyette P., Frosst P., Rosenblatt D.S., Rozen R. Seven novel mutations in the methylenetetrahydrofolate reductase gene and genotype/phenotype correlations in severe methylenetetrahydrofolate reductase deficiency. Am. J. Hum. Genet. 1995, 56:1052-1059.
    • (1995) Am. J. Hum. Genet. , vol.56 , pp. 1052-1059
    • Goyette, P.1    Frosst, P.2    Rosenblatt, D.S.3    Rozen, R.4
  • 59
    • 84872601036 scopus 로고    scopus 로고
    • Histone acetylation: molecular mnemonics on the chromatin
    • Graff J., Tsai L.H. Histone acetylation: molecular mnemonics on the chromatin. Nat. Rev. Neurosci. 2013, 14:97-111.
    • (2013) Nat. Rev. Neurosci. , vol.14 , pp. 97-111
    • Graff, J.1    Tsai, L.H.2
  • 60
    • 40049102090 scopus 로고    scopus 로고
    • Inheritance of an epigenetic mark: the CpG DNA methyltransferase 1 is required for de novo establishment of a complex pattern of non-CpG methylation
    • Grandjean V., Yaman R., Cuzin F., Rassoulzadegan M. Inheritance of an epigenetic mark: the CpG DNA methyltransferase 1 is required for de novo establishment of a complex pattern of non-CpG methylation. PLoS One 2007, 2:e1136.
    • (2007) PLoS One , vol.2 , pp. e1136
    • Grandjean, V.1    Yaman, R.2    Cuzin, F.3    Rassoulzadegan, M.4
  • 64
    • 84859747269 scopus 로고    scopus 로고
    • G9a/GLP histone lysine dimethyltransferase complex activity in the hippocampus and the entorhinal cortex is required for gene activation and silencing during memory consolidation
    • Gupta-Agarwal S., Franklin A.V., Deramus T., Wheelock M., Davis R.L., Mcmahon L.L., Lubin F.D. G9a/GLP histone lysine dimethyltransferase complex activity in the hippocampus and the entorhinal cortex is required for gene activation and silencing during memory consolidation. J. Neurosci. 2012, 32:5440-5453.
    • (2012) J. Neurosci. , vol.32 , pp. 5440-5453
    • Gupta-Agarwal, S.1    Franklin, A.V.2    Deramus, T.3    Wheelock, M.4    Davis, R.L.5    Mcmahon, L.L.6    Lubin, F.D.7
  • 68
    • 84891476446 scopus 로고    scopus 로고
    • Cancer epigenetics: new therapies and new challenges
    • Hatzimichael E., Crook T. Cancer epigenetics: new therapies and new challenges. J Drug Deliv 2013, 2013:529312.
    • (2013) J Drug Deliv , vol.2013 , pp. 529312
    • Hatzimichael, E.1    Crook, T.2
  • 69
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: small RNAs with a big role in gene regulation
    • He L., Hannon G.J. MicroRNAs: small RNAs with a big role in gene regulation. Nat. Rev. Genet. 2004, 5:522-531.
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 71
    • 84874940821 scopus 로고    scopus 로고
    • Genetics of the epilepsies: where are we and where are we going?
    • Helbig I., Lowenstein D.H. Genetics of the epilepsies: where are we and where are we going?. Curr. Opin. Neurol. 2013, 26:179-185.
    • (2013) Curr. Opin. Neurol. , vol.26 , pp. 179-185
    • Helbig, I.1    Lowenstein, D.H.2
  • 73
    • 33745007605 scopus 로고    scopus 로고
    • Functional and selective RNA interference in developing axons and growth cones
    • Hengst U., Cox L.J., Macosko E.Z., Jaffrey S.R. Functional and selective RNA interference in developing axons and growth cones. J. Neurosci. 2006, 26:5727-5732.
    • (2006) J. Neurosci. , vol.26 , pp. 5727-5732
    • Hengst, U.1    Cox, L.J.2    Macosko, E.Z.3    Jaffrey, S.R.4
  • 74
    • 84888358607 scopus 로고    scopus 로고
    • MicroRNAs in the pathophysiology and treatment of status epilepticus
    • Henshall D.C. MicroRNAs in the pathophysiology and treatment of status epilepticus. Front. Mol. Neurosci. 2013, 6:37.
    • (2013) Front. Mol. Neurosci. , vol.6 , pp. 37
    • Henshall, D.C.1
  • 75
    • 0037678473 scopus 로고    scopus 로고
    • The genetics of febrile seizures and related epilepsy syndromes
    • Hirose S., Mohney R.P., Okada M., Kaneko S., Mitsudome A. The genetics of febrile seizures and related epilepsy syndromes. Brain Dev. 2003, 25:304-312.
    • (2003) Brain Dev. , vol.25 , pp. 304-312
    • Hirose, S.1    Mohney, R.P.2    Okada, M.3    Kaneko, S.4    Mitsudome, A.5
  • 76
    • 84868706939 scopus 로고    scopus 로고
    • Redox regulation of the epigenetic landscape in cancer: a role for metabolic reprogramming in remodeling the epigenome
    • Hitchler M.J., Domann F.E. Redox regulation of the epigenetic landscape in cancer: a role for metabolic reprogramming in remodeling the epigenome. Free Radic. Biol. Med. 2012, 53:2178-2187.
    • (2012) Free Radic. Biol. Med. , vol.53 , pp. 2178-2187
    • Hitchler, M.J.1    Domann, F.E.2
  • 77
    • 84889573275 scopus 로고    scopus 로고
    • Histone lysine demethylases as targets for anticancer therapy
    • Hojfeldt J.W., Agger K., Helin K. Histone lysine demethylases as targets for anticancer therapy. Nat. Rev. Drug Discov. 2013, 12:917-930.
    • (2013) Nat. Rev. Drug Discov. , vol.12 , pp. 917-930
    • Hojfeldt, J.W.1    Agger, K.2    Helin, K.3
  • 78
    • 80051733376 scopus 로고    scopus 로고
    • Conditional deletion of NRSF in forebrain neurons accelerates epileptogenesis in the kindling model
    • Hu X.L., Cheng X., Cai L., Tan G.H., Xu L., Feng X.Y., Lu T.J., Xiong H., Fei J., Xiong Z.Q. Conditional deletion of NRSF in forebrain neurons accelerates epileptogenesis in the kindling model. Cereb. Cortex. 2011, 21(9):2158-2165.
    • (2011) Cereb. Cortex. , vol.21 , Issue.9 , pp. 2158-2165
    • Hu, X.L.1    Cheng, X.2    Cai, L.3    Tan, G.H.4    Xu, L.5    Feng, X.Y.6    Lu, T.J.7    Xiong, H.8    Fei, J.9    Xiong, Z.Q.10
  • 79
    • 0033306577 scopus 로고    scopus 로고
    • Transcriptional repression by REST: recruitment of Sin3A and histone deacetylase to neuronal genes
    • Huang Y., Myers S.J., Dingledine R. Transcriptional repression by REST: recruitment of Sin3A and histone deacetylase to neuronal genes. Nat. Neurosci. 1999, 2:867-872.
    • (1999) Nat. Neurosci. , vol.2 , pp. 867-872
    • Huang, Y.1    Myers, S.J.2    Dingledine, R.3
  • 80
    • 0036812485 scopus 로고    scopus 로고
    • Altered histone acetylation at glutamate receptor 2 and brain-derived neurotrophic factor genes is an early event triggered by status epilepticus
    • Huang Y., Doherty J.J., Dingledine R. Altered histone acetylation at glutamate receptor 2 and brain-derived neurotrophic factor genes is an early event triggered by status epilepticus. J. Neurosci. 2002, 22:8422-8428.
    • (2002) J. Neurosci. , vol.22 , pp. 8422-8428
    • Huang, Y.1    Doherty, J.J.2    Dingledine, R.3
  • 81
    • 84876694930 scopus 로고    scopus 로고
    • The role of genetics in the establishment and maintenance of the epigenome
    • Huidobro C., Fernandez A.F., Fraga M.F. The role of genetics in the establishment and maintenance of the epigenome. Cell. Mol. Life Sci. 2013, 70(9):1543-1573.
    • (2013) Cell. Mol. Life Sci. , vol.70 , Issue.9 , pp. 1543-1573
    • Huidobro, C.1    Fernandez, A.F.2    Fraga, M.F.3
  • 82
  • 83
    • 84875467145 scopus 로고    scopus 로고
    • Accumulation and loss of asymmetric non-CpG methylation during male germ-cell development
    • Ichiyanagi T., Ichiyanagi K., Miyake M., Sasaki H. Accumulation and loss of asymmetric non-CpG methylation during male germ-cell development. Nucleic Acids Res. 2013, 41:738-745.
    • (2013) Nucleic Acids Res. , vol.41 , pp. 738-745
    • Ichiyanagi, T.1    Ichiyanagi, K.2    Miyake, M.3    Sasaki, H.4
  • 86
    • 33745511260 scopus 로고    scopus 로고
    • Kainate exposure suppresses activation of GluR2 subunit promoter in primary cultured cerebral cortical neurons through induction of RE1-silencing transcription factor
    • Jia Y.H., Zhu X., Li S.Y., Ni J.H., Jia H.T. Kainate exposure suppresses activation of GluR2 subunit promoter in primary cultured cerebral cortical neurons through induction of RE1-silencing transcription factor. Neurosci. Lett. 2006, 403:103-108.
    • (2006) Neurosci. Lett. , vol.403 , pp. 103-108
    • Jia, Y.H.1    Zhu, X.2    Li, S.Y.3    Ni, J.H.4    Jia, H.T.5
  • 89
    • 84862208827 scopus 로고    scopus 로고
    • Crosstalk among epigenetic pathways regulates neurogenesis
    • Jobe E.M., Mcquate A.L., Zhao X. Crosstalk among epigenetic pathways regulates neurogenesis. Front. Neurosci. 2012, 6:59.
    • (2012) Front. Neurosci. , vol.6 , pp. 59
    • Jobe, E.M.1    Mcquate, A.L.2    Zhao, X.3
  • 90
    • 84875754667 scopus 로고    scopus 로고
    • Histone H4 Lysine 20 methylation: key player in epigenetic regulation of genomic integrity
    • Jørgensen S., Schotta G., Sørensen C.S. Histone H4 Lysine 20 methylation: key player in epigenetic regulation of genomic integrity. Nucleic Acids Res. 2013, 41:2797-2806.
    • (2013) Nucleic Acids Res. , vol.41 , pp. 2797-2806
    • Jørgensen, S.1    Schotta, G.2    Sørensen, C.S.3
  • 91
    • 84877092851 scopus 로고    scopus 로고
    • Comprehensive expression analyses of neural cell-type-specific miRNAs identify new determinants of the specification and maintenance of neuronal phenotypes
    • Jovicic A., Roshan R., Moisoi N., Pradervand S., Moser R., Pillai B., Luthi-Carter R. Comprehensive expression analyses of neural cell-type-specific miRNAs identify new determinants of the specification and maintenance of neuronal phenotypes. J. Neurosci. 2013, 33:5127-5137.
    • (2013) J. Neurosci. , vol.33 , pp. 5127-5137
    • Jovicic, A.1    Roshan, R.2    Moisoi, N.3    Pradervand, S.4    Moser, R.5    Pillai, B.6    Luthi-Carter, R.7
  • 92
    • 70350708160 scopus 로고    scopus 로고
    • Different timings of Dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system
    • Kawase-Koga Y., Otaegi G., Sun T. Different timings of Dicer deletion affect neurogenesis and gliogenesis in the developing mouse central nervous system. Dev. Dyn. 2009, 238:2800-2812.
    • (2009) Dev. Dyn. , vol.238 , pp. 2800-2812
    • Kawase-Koga, Y.1    Otaegi, G.2    Sun, T.3
  • 93
    • 53249130741 scopus 로고    scopus 로고
    • Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
    • Kazantsev A.G., Thompson L.M. Therapeutic application of histone deacetylase inhibitors for central nervous system disorders. Nat. Rev. Drug Discov. 2008, 7:854-868.
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 854-868
    • Kazantsev, A.G.1    Thompson, L.M.2
  • 94
  • 96
    • 44949246486 scopus 로고    scopus 로고
    • A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome
    • Khalil A.M., Faghihi M.A., Modarresi F., Brothers S.P., Wahlestedt C. A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome. PLoS One 2008, 3:e1486.
    • (2008) PLoS One , vol.3 , pp. e1486
    • Khalil, A.M.1    Faghihi, M.A.2    Modarresi, F.3    Brothers, S.P.4    Wahlestedt, C.5
  • 98
    • 77955051048 scopus 로고    scopus 로고
    • Role of histone acetylation in cell physiology and diseases: an update
    • Khan S.N., Khan A.U. Role of histone acetylation in cell physiology and diseases: an update. Clin. Chim. Acta 2010, 411:1401-1411.
    • (2010) Clin. Chim. Acta , vol.411 , pp. 1401-1411
    • Khan, S.N.1    Khan, A.U.2
  • 99
    • 0842324785 scopus 로고    scopus 로고
    • The nucleosome: from genomic organization to genomic regulation
    • Khorasanizadeh S. The nucleosome: from genomic organization to genomic regulation. Cell 2004, 116:259-272.
    • (2004) Cell , vol.116 , pp. 259-272
    • Khorasanizadeh, S.1
  • 103
    • 55349117504 scopus 로고    scopus 로고
    • Glucose transporter deficiency syndrome (GLUT1DS) and the ketogenic diet
    • Klepper J. Glucose transporter deficiency syndrome (GLUT1DS) and the ketogenic diet. Epilepsia 2008, 49(Suppl. 8):46-49.
    • (2008) Epilepsia , vol.49 , pp. 46-49
    • Klepper, J.1
  • 104
    • 84874547925 scopus 로고    scopus 로고
    • Regulatory mechanisms of long noncoding RNAs in vertebrate central nervous system development and function
    • Knauss J.L., Sun T. Regulatory mechanisms of long noncoding RNAs in vertebrate central nervous system development and function. Neuroscience 2013, 235:200-214.
    • (2013) Neuroscience , vol.235 , pp. 200-214
    • Knauss, J.L.1    Sun, T.2
  • 105
    • 79960108626 scopus 로고    scopus 로고
    • The methylation hypothesis: do epigenetic chromatin modifications play a role in epileptogenesis?
    • Kobow K., Blumcke I. The methylation hypothesis: do epigenetic chromatin modifications play a role in epileptogenesis?. Epilepsia 2011, 52(Suppl. 4):15-19.
    • (2011) Epilepsia , vol.52 , pp. 15-19
    • Kobow, K.1    Blumcke, I.2
  • 106
    • 84873133424 scopus 로고    scopus 로고
    • The emerging role of DNA methylation in epileptogenesis
    • Kobow K., Blumcke I. The emerging role of DNA methylation in epileptogenesis. Epilepsia 2012, 53(Suppl. 9):11-20.
    • (2012) Epilepsia , vol.53 , pp. 11-20
    • Kobow, K.1    Blumcke, I.2
  • 108
    • 84880469058 scopus 로고    scopus 로고
    • The methylation hypothesis of pharmacoresistance in epilepsy
    • Kobow K., El-Osta A., Blumcke I. The methylation hypothesis of pharmacoresistance in epilepsy. Epilepsia 2013, 54(Suppl. 2):41-47.
    • (2013) Epilepsia , vol.54 , pp. 41-47
    • Kobow, K.1    El-Osta, A.2    Blumcke, I.3
  • 111
    • 84875255103 scopus 로고    scopus 로고
    • Energy depletion in seizures: anaplerosis as a strategy for future therapies
    • Kovac S., Abramov A.Y., Walker M.C. Energy depletion in seizures: anaplerosis as a strategy for future therapies. Neuropharmacology 2013, 69:96-104.
    • (2013) Neuropharmacology , vol.69 , pp. 96-104
    • Kovac, S.1    Abramov, A.Y.2    Walker, M.C.3
  • 112
    • 0036591878 scopus 로고    scopus 로고
    • The many faces of histone lysine methylation
    • Lachner M., Jenuwein T. The many faces of histone lysine methylation. Curr. Opin. Cell Biol. 2002, 14:286-298.
    • (2002) Curr. Opin. Cell Biol. , vol.14 , pp. 286-298
    • Lachner, M.1    Jenuwein, T.2
  • 116
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li E., Bestor T.H., Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992, 69:915-926.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 117
    • 84869016176 scopus 로고    scopus 로고
    • Activity-dependent human brain coding/noncoding gene regulatory networks
    • Lipovich L., Dachet F., Cai J., Bagla S., Balan K., Jia H., Loeb J.A. Activity-dependent human brain coding/noncoding gene regulatory networks. Genetics 2012, 192:1133-1148.
    • (2012) Genetics , vol.192 , pp. 1133-1148
    • Lipovich, L.1    Dachet, F.2    Cai, J.3    Bagla, S.4    Balan, K.5    Jia, H.6    Loeb, J.A.7
  • 120
    • 84861895155 scopus 로고    scopus 로고
    • Neuronal conditional knockout of NRSF decreases vulnerability to seizures induced by pentylenetetrazol in mice
    • Liu M., Sheng Z., Cai L., Zhao K., Tian Y., Fei J. Neuronal conditional knockout of NRSF decreases vulnerability to seizures induced by pentylenetetrazol in mice. Acta Biochim. Biophys. Sin. 2012, 44:476-482.
    • (2012) Acta Biochim. Biophys. Sin. , vol.44 , pp. 476-482
    • Liu, M.1    Sheng, Z.2    Cai, L.3    Zhao, K.4    Tian, Y.5    Fei, J.6
  • 121
    • 39349105090 scopus 로고    scopus 로고
    • Expanding chemical biology of 2-oxoglutarate oxygenases
    • Loenarz C., Schofield C.J. Expanding chemical biology of 2-oxoglutarate oxygenases. Nat. Chem. Biol. 2008, 4:152-156.
    • (2008) Nat. Chem. Biol. , vol.4 , pp. 152-156
    • Loenarz, C.1    Schofield, C.J.2
  • 123
    • 84880917068 scopus 로고    scopus 로고
    • PIWI-interacting RNAs: from generation to transgenerational epigenetics
    • Luteijn M.J., Ketting R.F. PIWI-interacting RNAs: from generation to transgenerational epigenetics. Nat. Rev. Genet. 2013, 14:523-534.
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 523-534
    • Luteijn, M.J.1    Ketting, R.F.2
  • 124
  • 127
    • 34147158728 scopus 로고    scopus 로고
    • The Chd family of chromatin remodelers
    • Marfella C.G., Imbalzano A.N. The Chd family of chromatin remodelers. Mutat. Res. 2007, 618:30-40.
    • (2007) Mutat. Res. , vol.618 , pp. 30-40
    • Marfella, C.G.1    Imbalzano, A.N.2
  • 129
    • 27644589675 scopus 로고    scopus 로고
    • The diverse functions of histone lysine methylation
    • Martin C., Zhang Y. The diverse functions of histone lysine methylation. Nat. Rev. Mol. Cell Biol. 2005, 6:838-849.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 838-849
    • Martin, C.1    Zhang, Y.2
  • 130
    • 75749093015 scopus 로고    scopus 로고
    • Deregulation of H3K27 methylation in cancer
    • Martinez-Garcia E., Licht J.D. Deregulation of H3K27 methylation in cancer. Nat. Genet. 2010, 42:100-101.
    • (2010) Nat. Genet. , vol.42 , pp. 100-101
    • Martinez-Garcia, E.1    Licht, J.D.2
  • 131
    • 0242300612 scopus 로고    scopus 로고
    • DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation
    • Martinowich K., Hattori D., Wu H., Fouse S., He F., Hu Y., Fan G., Sun Y.E. DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation. Science 2003, 302:890-893.
    • (2003) Science , vol.302 , pp. 890-893
    • Martinowich, K.1    Hattori, D.2    Wu, H.3    Fouse, S.4    He, F.5    Hu, Y.6    Fan, G.7    Sun, Y.E.8
  • 132
    • 84869095296 scopus 로고    scopus 로고
    • Mechanisms of ketogenic diet action
    • Oxford University Press, Oxford, J.L. Noebels, M. Avoli, M.A. Rogawski, R.W. Olsen, A.V. Delgado-Escueta (Eds.)
    • Masino S.A., Rho J.M. Mechanisms of ketogenic diet action. Jasper's Basic Mechanisms of the Epilepsies (Contemporary Neurology Series) 2012, Oxford University Press, Oxford. fourth ed. J.L. Noebels, M. Avoli, M.A. Rogawski, R.W. Olsen, A.V. Delgado-Escueta (Eds.).
    • (2012) Jasper's Basic Mechanisms of the Epilepsies (Contemporary Neurology Series)
    • Masino, S.A.1    Rho, J.M.2
  • 135
    • 84871563384 scopus 로고    scopus 로고
    • MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
    • Mellen M., Ayata P., Dewell S., Kriaucionis S., Heintz N. MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell 2012, 151:1417-1430.
    • (2012) Cell , vol.151 , pp. 1417-1430
    • Mellen, M.1    Ayata, P.2    Dewell, S.3    Kriaucionis, S.4    Heintz, N.5
  • 136
    • 84863505435 scopus 로고    scopus 로고
    • Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a
    • Meng L., Person R.E., Beaudet A.L. Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a. Hum. Mol. Genet. 2012, 21:3001-3012.
    • (2012) Hum. Mol. Genet. , vol.21 , pp. 3001-3012
    • Meng, L.1    Person, R.E.2    Beaudet, A.L.3
  • 137
  • 138
    • 84890176335 scopus 로고    scopus 로고
    • RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination
    • Metzger M.B., Pruneda J.N., Klevit R.E., Weissman A.M. RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination. Biochim. Biophys. Acta 2014, 1843:47-60.
    • (2014) Biochim. Biophys. Acta , vol.1843 , pp. 47-60
    • Metzger, M.B.1    Pruneda, J.N.2    Klevit, R.E.3    Weissman, A.M.4
  • 139
    • 33847614418 scopus 로고    scopus 로고
    • Covalent modification of DNA regulates memory formation
    • Miller C.A., Sweatt J.D. Covalent modification of DNA regulates memory formation. Neuron 2007, 53:857-869.
    • (2007) Neuron , vol.53 , pp. 857-869
    • Miller, C.A.1    Sweatt, J.D.2
  • 141
    • 84855402974 scopus 로고    scopus 로고
    • Concise review: pluripotency and the transcriptional inactivation of the female mammalian X chromosome
    • Minkovsky A., Patel S., Plath K. Concise review: pluripotency and the transcriptional inactivation of the female mammalian X chromosome. Stem Cells 2012, 30:48-54.
    • (2012) Stem Cells , vol.30 , pp. 48-54
    • Minkovsky, A.1    Patel, S.2    Plath, K.3
  • 142
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • Molofsky A.V., Pardal R., Iwashita T., Park I.K., Clarke M.F., Morrison S.J. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 2003, 425:962-967.
    • (2003) Nature , vol.425 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3    Park, I.K.4    Clarke, M.F.5    Morrison, S.J.6
  • 143
    • 0037335034 scopus 로고    scopus 로고
    • How the ubiquitin-proteasome system controls transcription
    • Muratani M., Tansey W.P. How the ubiquitin-proteasome system controls transcription. Nat. Rev. Mol. Cell Biol. 2003, 4:192-201.
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 192-201
    • Muratani, M.1    Tansey, W.P.2
  • 144
    • 38349044361 scopus 로고    scopus 로고
    • Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation
    • Nelson E.D., Kavalali E.T., Monteggia L.M. Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation. J. Neurosci. 2008, 28:395-406.
    • (2008) J. Neurosci. , vol.28 , pp. 395-406
    • Nelson, E.D.1    Kavalali, E.T.2    Monteggia, L.M.3
  • 146
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M., Bell D.W., Haber D.A., Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999, 99:247-257.
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 148
    • 0033930737 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase 677C>T mutation and epilepsy
    • Ono H., Sakamoto A., Mizoguchi N., Sakura N. Methylenetetrahydrofolate reductase 677C>T mutation and epilepsy. J. Inherit. Metab. Dis. 2000, 23:525-526.
    • (2000) J. Inherit. Metab. Dis. , vol.23 , pp. 525-526
    • Ono, H.1    Sakamoto, A.2    Mizoguchi, N.3    Sakura, N.4
  • 149
    • 77950876088 scopus 로고    scopus 로고
    • REST is a key regulator in brain-specific homeobox gene expression during neuronal differentiation
    • Park S.Y., Kim J.B., Han Y.-M. REST is a key regulator in brain-specific homeobox gene expression during neuronal differentiation. J. Neurochem. 2007, 103:2565-2574.
    • (2007) J. Neurochem. , vol.103 , pp. 2565-2574
    • Park, S.Y.1    Kim, J.B.2    Han, Y.-M.3
  • 150
    • 8544253949 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress: cause and consequence of epileptic seizures
    • Patel M. Mitochondrial dysfunction and oxidative stress: cause and consequence of epileptic seizures. Free Radic. Biol. Med. 2004, 37:1951-1962.
    • (2004) Free Radic. Biol. Med. , vol.37 , pp. 1951-1962
    • Patel, M.1
  • 152
    • 0030763923 scopus 로고    scopus 로고
    • The GluR2 (GluR-B) hypothesis: Ca(2+)-permeable AMPA receptors in neurological disorders
    • Pellegrini-Giampietro D.E., Gorter J.A., Bennett M.V., Zukin R.S. The GluR2 (GluR-B) hypothesis: Ca(2+)-permeable AMPA receptors in neurological disorders. Trends Neurosci. 1997, 20:464-470.
    • (1997) Trends Neurosci. , vol.20 , pp. 464-470
    • Pellegrini-Giampietro, D.E.1    Gorter, J.A.2    Bennett, M.V.3    Zukin, R.S.4
  • 153
    • 84878236414 scopus 로고    scopus 로고
    • Expression patterns of miR-124, miR-134, miR-132, and miR-21 in an immature rat model and children with mesial temporal lobe epilepsy
    • Peng J., Omran A., Ashhab M.U., Kong H., Gan N., He F., Yin F. Expression patterns of miR-124, miR-134, miR-132, and miR-21 in an immature rat model and children with mesial temporal lobe epilepsy. J. Mol. Neurosci. 2013, 50:291-297.
    • (2013) J. Mol. Neurosci. , vol.50 , pp. 291-297
    • Peng, J.1    Omran, A.2    Ashhab, M.U.3    Kong, H.4    Gan, N.5    He, F.6    Yin, F.7
  • 154
    • 0035283058 scopus 로고    scopus 로고
    • Human morbid genetics revisited: relevance of epigenetics
    • Petronis A. Human morbid genetics revisited: relevance of epigenetics. Trends Genet. 2001, 17:142-146.
    • (2001) Trends Genet. , vol.17 , pp. 142-146
    • Petronis, A.1
  • 155
    • 0029827343 scopus 로고    scopus 로고
    • ATRX encodes a novel member of the SNF2 family of proteins: mutations point to a common mechanism underlying the ATR-X syndrome
    • Picketts D.J., Higgs D.R., Bachoo S., Blake D.J., Quarrell O.W., Gibbons R.J. ATRX encodes a novel member of the SNF2 family of proteins: mutations point to a common mechanism underlying the ATR-X syndrome. Hum. Mol. Genet. 1996, 5:1899-1907.
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 1899-1907
    • Picketts, D.J.1    Higgs, D.R.2    Bachoo, S.3    Blake, D.J.4    Quarrell, O.W.5    Gibbons, R.J.6
  • 157
    • 79957603217 scopus 로고    scopus 로고
    • Epilepsy genetics-past, present, and future
    • Poduri A., Lowenstein D. Epilepsy genetics-past, present, and future. Curr. Opin. Genet. Dev. 2011, 21:325-332.
    • (2011) Curr. Opin. Genet. Dev. , vol.21 , pp. 325-332
    • Poduri, A.1    Lowenstein, D.2
  • 159
    • 37549064016 scopus 로고    scopus 로고
    • Cerebral metabolic adaptation and ketone metabolism after brain injury
    • Prins M.L. Cerebral metabolic adaptation and ketone metabolism after brain injury. J. Cereb. Blood Flow Metab. 2008, 28:1-16.
    • (2008) J. Cereb. Blood Flow Metab. , vol.28 , pp. 1-16
    • Prins, M.L.1
  • 160
    • 77952887283 scopus 로고    scopus 로고
    • Epigenetic mechanisms underlying human epileptic disorders and the process of epileptogenesis
    • Qureshi I.A., Mehler M.F. Epigenetic mechanisms underlying human epileptic disorders and the process of epileptogenesis. Neurobiol. Dis. 2010, 39:53-60.
    • (2010) Neurobiol. Dis. , vol.39 , pp. 53-60
    • Qureshi, I.A.1    Mehler, M.F.2
  • 161
    • 84864126183 scopus 로고    scopus 로고
    • Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease
    • Qureshi I.A., Mehler M.F. Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease. Nat. Rev. Neurosci. 2012, 13:528-541.
    • (2012) Nat. Rev. Neurosci. , vol.13 , pp. 528-541
    • Qureshi, I.A.1    Mehler, M.F.2
  • 162
    • 68949151925 scopus 로고    scopus 로고
    • Loss of the putative catalytic domain of HDAC4 leads to reduced thermal nociception and seizures while allowing normal bone development
    • Rajan I., Savelieva K.V., Ye G.L., Wang C.Y., Malbari M.M., Friddle C., Lanthorn T.H., Zhang W. Loss of the putative catalytic domain of HDAC4 leads to reduced thermal nociception and seizures while allowing normal bone development. PLoS One 2009, 4:e6612.
    • (2009) PLoS One , vol.4 , pp. e6612
    • Rajan, I.1    Savelieva, K.V.2    Ye, G.L.3    Wang, C.Y.4    Malbari, M.M.5    Friddle, C.6    Lanthorn, T.H.7    Zhang, W.8
  • 163
    • 70350787254 scopus 로고    scopus 로고
    • Epileptogenesis in the immature brain: emerging mechanisms
    • Rakhade S.N., Jensen F.E. Epileptogenesis in the immature brain: emerging mechanisms. Nat. Rev. Neurol. 2009, 5:380-391.
    • (2009) Nat. Rev. Neurol. , vol.5 , pp. 380-391
    • Rakhade, S.N.1    Jensen, F.E.2
  • 164
    • 84860371870 scopus 로고    scopus 로고
    • Combinatorial complexity in chromatin structure and function: revisiting the histone code
    • Rando O.J. Combinatorial complexity in chromatin structure and function: revisiting the histone code. Curr. Opin. Genet. Dev. 2012, 22:148-155.
    • (2012) Curr. Opin. Genet. Dev. , vol.22 , pp. 148-155
    • Rando, O.J.1
  • 165
    • 0019318994 scopus 로고
    • DNA methylation and gene function
    • Razin A., Riggs A.D. DNA methylation and gene function. Science 1980, 210:604-610.
    • (1980) Science , vol.210 , pp. 604-610
    • Razin, A.1    Riggs, A.D.2
  • 166
    • 34249279527 scopus 로고    scopus 로고
    • Stability and flexibility of epigenetic gene regulation in mammalian development
    • Reik W. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 2007, 447:425-432.
    • (2007) Nature , vol.447 , pp. 425-432
    • Reik, W.1
  • 167
    • 84861904178 scopus 로고    scopus 로고
    • Genome regulation by long noncoding RNAs
    • Rinn J.L., Chang H.Y. Genome regulation by long noncoding RNAs. Annu. Rev. Biochem. 2012, 81:145-166.
    • (2012) Annu. Rev. Biochem. , vol.81 , pp. 145-166
    • Rinn, J.L.1    Chang, H.Y.2
  • 168
    • 84876686460 scopus 로고    scopus 로고
    • From neural development to cognition: unexpected roles for chromatin
    • Ronan J.L., Wu W., Crabtree G.R. From neural development to cognition: unexpected roles for chromatin. Nat. Rev. Genet. 2013, 14:347-359.
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 347-359
    • Ronan, J.L.1    Wu, W.2    Crabtree, G.R.3
  • 170
    • 84880935246 scopus 로고    scopus 로고
    • Status epilepticus triggers early and late alterations in brain-derived neurotrophic factor and NMDA glutamate receptor Grin2b DNA methylation levels in the hippocampus
    • Ryley Parrish R., Albertson A.J., Buckingham S.C., Hablitz J.J., Mascia K.L., Davis Haselden W., Lubin F.D. Status epilepticus triggers early and late alterations in brain-derived neurotrophic factor and NMDA glutamate receptor Grin2b DNA methylation levels in the hippocampus. Neuroscience 2013, 248C:602-619.
    • (2013) Neuroscience , vol.248 C , pp. 602-619
    • Ryley Parrish, R.1    Albertson, A.J.2    Buckingham, S.C.3    Hablitz, J.J.4    Mascia, K.L.5    Davis Haselden, W.6    Lubin, F.D.7
  • 171
    • 84874815449 scopus 로고    scopus 로고
    • SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus
    • Saharan S., Jhaveri D.J., Bartlett P.F. SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus. J. Neurosci. Res. 2013, 91:642-659.
    • (2013) J. Neurosci. Res. , vol.91 , pp. 642-659
    • Saharan, S.1    Jhaveri, D.J.2    Bartlett, P.F.3
  • 172
    • 0035887598 scopus 로고    scopus 로고
    • Decreased glutamate receptor 2 expression and enhanced epileptogenesis in immature rat hippocampus after perinatal hypoxia-induced seizures
    • Sanchez R.M., Koh S., Rio C., Wang C., Lamperti E.D., Sharma D., Corfas G., Jensen F.E. Decreased glutamate receptor 2 expression and enhanced epileptogenesis in immature rat hippocampus after perinatal hypoxia-induced seizures. J. Neurosci. 2001, 21:8154-8163.
    • (2001) J. Neurosci. , vol.21 , pp. 8154-8163
    • Sanchez, R.M.1    Koh, S.2    Rio, C.3    Wang, C.4    Lamperti, E.D.5    Sharma, D.6    Corfas, G.7    Jensen, F.E.8
  • 173
    • 84871139031 scopus 로고    scopus 로고
    • Naturally occurring carboxypeptidase A6 mutations: effect on enzyme function and association with epilepsy
    • Sapio M.R., Salzmann A., Vessaz M., Crespel A., Lyons P.J., Malafosse A., Fricker L.D. Naturally occurring carboxypeptidase A6 mutations: effect on enzyme function and association with epilepsy. J. Biol. Chem. 2012, 287:42900-42909.
    • (2012) J. Biol. Chem. , vol.287 , pp. 42900-42909
    • Sapio, M.R.1    Salzmann, A.2    Vessaz, M.3    Crespel, A.4    Lyons, P.J.5    Malafosse, A.6    Fricker, L.D.7
  • 175
    • 78650329157 scopus 로고    scopus 로고
    • Neuroscience: Angelman syndrome connections
    • Scheiffele P., Beg A.A. Neuroscience: Angelman syndrome connections. Nature 2010, 468:907-908.
    • (2010) Nature , vol.468 , pp. 907-908
    • Scheiffele, P.1    Beg, A.A.2
  • 178
    • 77955082451 scopus 로고    scopus 로고
    • ARX spectrum disorders: making inroads into the molecular pathology
    • Shoubridge C., Fullston T., Gecz J. ARX spectrum disorders: making inroads into the molecular pathology. Hum. Mutat. 2010, 31:889-900.
    • (2010) Hum. Mutat. , vol.31 , pp. 889-900
    • Shoubridge, C.1    Fullston, T.2    Gecz, J.3
  • 179
    • 84874194072 scopus 로고    scopus 로고
    • DNA methylation: roles in mammalian development
    • Smith Z.D., Meissner A. DNA methylation: roles in mammalian development. Nat. Rev. Genet. 2013, 14:204-220.
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 204-220
    • Smith, Z.D.1    Meissner, A.2
  • 180
    • 23444437474 scopus 로고    scopus 로고
    • Inhibition of histone deacetylation by trichostatin A intensifies the transcriptions of neuronal c-fos and c-jun genes after kainate stimulation
    • Sng J.C., Taniura H., Yoneda Y. Inhibition of histone deacetylation by trichostatin A intensifies the transcriptions of neuronal c-fos and c-jun genes after kainate stimulation. Neurosci. Lett. 2005, 386:150-155.
    • (2005) Neurosci. Lett. , vol.386 , pp. 150-155
    • Sng, J.C.1    Taniura, H.2    Yoneda, Y.3
  • 181
    • 33645059712 scopus 로고    scopus 로고
    • Histone modifications in kainate-induced status epilepticus
    • Sng J.C., Taniura H., Yoneda Y. Histone modifications in kainate-induced status epilepticus. Eur. J. Neurosci. 2006, 23:1269-1282.
    • (2006) Eur. J. Neurosci. , vol.23 , pp. 1269-1282
    • Sng, J.C.1    Taniura, H.2    Yoneda, Y.3
  • 183
    • 84870184296 scopus 로고    scopus 로고
    • Genetic deletion of Gadd45b, a regulator of active DNA demethylation, enhances long-term memory and synaptic plasticity
    • Sultan F.A., Wang J., Tront J., Liebermann D.A., Sweatt J.D. Genetic deletion of Gadd45b, a regulator of active DNA demethylation, enhances long-term memory and synaptic plasticity. J. Neurosci. 2012, 32:17059-17066.
    • (2012) J. Neurosci. , vol.32 , pp. 17059-17066
    • Sultan, F.A.1    Wang, J.2    Tront, J.3    Liebermann, D.A.4    Sweatt, J.D.5
  • 186
    • 77951583810 scopus 로고    scopus 로고
    • Epigenetic regulation of TLR4 gene expression in intestinal epithelial cells for the maintenance of intestinal homeostasis
    • Takahashi K., Sugi Y., Hosono A., Kaminogawa S. Epigenetic regulation of TLR4 gene expression in intestinal epithelial cells for the maintenance of intestinal homeostasis. J. Immunol. 2009, 183:6522-6529.
    • (2009) J. Immunol. , vol.183 , pp. 6522-6529
    • Takahashi, K.1    Sugi, Y.2    Hosono, A.3    Kaminogawa, S.4
  • 187
    • 38049025837 scopus 로고    scopus 로고
    • PR-Set7-dependent lysine methylation ensures genome replication and stability through S phase
    • Tardat M., Murr R., Herceg Z., Sardet C., Julien E. PR-Set7-dependent lysine methylation ensures genome replication and stability through S phase. J. Cell Biol. 2007, 179:1413-1426.
    • (2007) J. Cell Biol. , vol.179 , pp. 1413-1426
    • Tardat, M.1    Murr, R.2    Herceg, Z.3    Sardet, C.4    Julien, E.5
  • 188
    • 3042589127 scopus 로고    scopus 로고
    • Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures
    • Tsankova N.M., Kumar A., Nestler E.J. Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures. J. Neurosci. 2004, 24:5603-5610.
    • (2004) J. Neurosci. , vol.24 , pp. 5603-5610
    • Tsankova, N.M.1    Kumar, A.2    Nestler, E.J.3
  • 193
    • 36749026906 scopus 로고    scopus 로고
    • Switching from repression to activation: microRNAs can up-regulate translation
    • Vasudevan S., Tong Y., Steitz J.A. Switching from repression to activation: microRNAs can up-regulate translation. Science 2007, 318:1931-1934.
    • (2007) Science , vol.318 , pp. 1931-1934
    • Vasudevan, S.1    Tong, Y.2    Steitz, J.A.3
  • 194
    • 34848863567 scopus 로고    scopus 로고
    • New roles for interleukin-1 beta in the mechanisms of epilepsy
    • Vezzani A., Baram T.Z. New roles for interleukin-1 beta in the mechanisms of epilepsy. Epilepsy Curr. 2007, 7:45-50.
    • (2007) Epilepsy Curr. , vol.7 , pp. 45-50
    • Vezzani, A.1    Baram, T.Z.2
  • 199
    • 84856998951 scopus 로고    scopus 로고
    • The long arm of long noncoding RNAs: roles as sensors regulating gene transcriptional programs
    • Wang X., Song X., Glass C.K., Rosenfeld M.G. The long arm of long noncoding RNAs: roles as sensors regulating gene transcriptional programs. Cold Spring Harb. Perspect. Biol. 2011, 3:a003756.
    • (2011) Cold Spring Harb. Perspect. Biol. , vol.3 , pp. a003756
    • Wang, X.1    Song, X.2    Glass, C.K.3    Rosenfeld, M.G.4
  • 200
    • 84870856116 scopus 로고    scopus 로고
    • Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum
    • Wang T., Pan Q., Lin L., Szulwach K.E., Song C.X., He C., Wu H., Warren S.T., Jin P., Duan R., Li X. Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum. Hum. Mol. Genet. 2012, 21:5500-5510.
    • (2012) Hum. Mol. Genet. , vol.21 , pp. 5500-5510
    • Wang, T.1    Pan, Q.2    Lin, L.3    Szulwach, K.E.4    Song, C.X.5    He, C.6    Wu, H.7    Warren, S.T.8    Jin, P.9    Duan, R.10    Li, X.11
  • 201
  • 203
    • 77956095231 scopus 로고    scopus 로고
    • Active DNA demethylation: many roads lead to Rome
    • Wu S.C., Zhang Y. Active DNA demethylation: many roads lead to Rome. Nat. Rev. Mol. Cell Biol. 2010, 11:607-620.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 607-620
    • Wu, S.C.1    Zhang, Y.2
  • 204
    • 46349105014 scopus 로고    scopus 로고
    • Cooperation between EZH2, NSPc1-mediated histone H2A ubiquitination and Dnmt1 in HOX gene silencing
    • Wu X., Gong Y., Yue J., Qiang B., Yuan J., Peng X. Cooperation between EZH2, NSPc1-mediated histone H2A ubiquitination and Dnmt1 in HOX gene silencing. Nucleic Acids Res. 2008, 36:3590-3599.
    • (2008) Nucleic Acids Res. , vol.36 , pp. 3590-3599
    • Wu, X.1    Gong, Y.2    Yue, J.3    Qiang, B.4    Yuan, J.5    Peng, X.6
  • 205
    • 2942592402 scopus 로고    scopus 로고
    • The effects of brain-derived neurotrophic factor (BDNF) administration on kindling induction, Trk expression and seizure-related morphological changes
    • Xu B., Michalski B., Racine R.J., Fahnestock M. The effects of brain-derived neurotrophic factor (BDNF) administration on kindling induction, Trk expression and seizure-related morphological changes. Neuroscience 2004, 126:521-531.
    • (2004) Neuroscience , vol.126 , pp. 521-531
    • Xu, B.1    Michalski, B.2    Racine, R.J.3    Fahnestock, M.4
  • 207
    • 0344442779 scopus 로고    scopus 로고
    • Transcriptional regulation by histone ubiquitination and deubiquitination
    • Zhang Y. Transcriptional regulation by histone ubiquitination and deubiquitination. Genes Dev. 2003, 17:2733-2740.
    • (2003) Genes Dev. , vol.17 , pp. 2733-2740
    • Zhang, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.