메뉴 건너뛰기




Volumn 6, Issue NOV, 2013, Pages

MicroRNAs in the pathophysiology and treatment of status epilepticus

Author keywords

Argonuate; Dicer; Epilepsy; Epileptogenesis; Hippocampal sclerosis; miRNA; Non coding RNA; RNA induced silencing complex

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; BIOLOGICAL MARKER; MICRORNA;

EID: 84888358607     PISSN: 16625099     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnmol.2013.00037     Document Type: Article
Times cited : (60)

References (138)
  • 1
    • 84855490109 scopus 로고    scopus 로고
    • Neuronal differentiation by TAp73 is mediated by microRNA34a regulation of synaptic protein targets
    • doi: 10.1073/pnas.1112061109
    • Agostini, M., Tucci, P., Killick, R., Candi, E., Sayan, B. S., Rivetti Cervo, P., et al. (2011). Neuronal differentiation by TAp73 is mediated by microRNA34a regulation of synaptic protein targets. Proc. Natl. Acad. Sci. U.S.A. 108, 21093-21098. doi: 10.1073/pnas.1112061109
    • (2011) Proc. Natl. Acad. Sci. U.S.A , vol.108 , pp. 21093-21098
    • Agostini, M.1    Tucci, P.2    Killick, R.3    Candi, E.4    Sayan, B.S.5    Rivetti, C.P.6
  • 2
    • 79953858598 scopus 로고    scopus 로고
    • Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
    • doi: 10.1038/nbt.1807
    • Alvarez-Erviti, L., Seow, Y., Yin, H., Betts, C., Lakhal, S., and Wood, M. J. (2011). Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes. Nat. Biotechnol. 29, 341-345. doi: 10.1038/nbt.1807
    • (2011) Nat. Biotechnol , vol.29 , pp. 341-345
    • Alvarez-Erviti, L.1    Seow, Y.2    Yin, H.3    Betts, C.4    Lakhal, S.5    Wood, M.J.6
  • 3
    • 84876046735 scopus 로고    scopus 로고
    • Oncomir miR-125b suppresses p14(ARF) to modulate p53-dependent and p53-independent apoptosis in prostate cancer
    • doi: 10.1371/journal.pone.0061064
    • Amir, S., Ma, A. H., Shi, X. B., Xue, L., Kung, H. J., and Devere White, R. W. (2013). Oncomir miR-125b suppresses p14(ARF) to modulate p53-dependent and p53-independent apoptosis in prostate cancer. PLoS ONE 8:e61064. doi: 10.1371/journal.pone.0061064
    • (2013) PLoS ONE , vol.8
    • Amir, S.1    Ma, A.H.2    Shi, X.B.3    Xue, L.4    Kung, H.J.5    Devere, W.R.W.6
  • 4
    • 77949549835 scopus 로고    scopus 로고
    • Expression pattern of miR-146a, an inflammation-associated microRNA, in experimental and human temporal lobe epilepsy
    • doi: 10.1111/j.1460-9568.2010.07122.x
    • Aronica, E., Fluiter, K., Iyer, A., Zurolo, E., Vreijling, J., Van Vliet, E. A., et al. (2010). Expression pattern of miR-146a, an inflammation-associated microRNA, in experimental and human temporal lobe epilepsy. Eur. J. Neurosci. 31, 1100--1107. doi: 10.1111/j.1460-9568.2010.07122.x
    • (2010) Eur. J. Neurosci , vol.31 , pp. 1100-1107
    • Aronica, E.1    Fluiter, K.2    Iyer, A.3    Zurolo, E.4    Vreijling, J.5    van Vliet, E.A.6
  • 5
    • 79953202200 scopus 로고    scopus 로고
    • Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma
    • doi: 10.1073/pnas.1019055108
    • Arroyo, J. D., Chevillet, J. R., Kroh, E. M., Ruf, I. K., Pritchard, C. C., Gibson, D. F., et al. (2011). Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proc. Natl. Acad. Sci. U.S.A. 108, 5003-5008. doi: 10.1073/pnas.1019055108
    • (2011) Proc. Natl. Acad. Sci. U.S.A , vol.108 , pp. 5003-5008
    • Arroyo, J.D.1    Chevillet, J.R.2    Kroh, E.M.3    Ruf, I.K.4    Pritchard, C.C.5    Gibson, D.F.6
  • 6
    • 84885956684 scopus 로고    scopus 로고
    • Expressions of tumor necrosis factor alpha and microRNA-155 in immature rat model of status epilepticus and children with mesial temporal lobe epilepsy
    • doi: 10.1007/s12031-013-0013-9
    • Ashhab, M. U., Omran, A., Kong, H., Gan, N., He, F., Peng, J., et al. (2013). Expressions of tumor necrosis factor alpha and microRNA-155 in immature rat model of status epilepticus and children with mesial temporal lobe epilepsy. J. Mol. Neurosci. 51, 950-958. doi: 10.1007/s12031-013-0013-9
    • (2013) J. Mol. Neurosci , vol.51 , pp. 950-958
    • Ashhab, M.U.1    Omran, A.2    Kong, H.3    Gan, N.4    He, F.5    Peng, J.6
  • 7
    • 49949116902 scopus 로고    scopus 로고
    • The impact of microRNAs on protein output
    • doi: 10.1038/nature07242
    • Baek, D., Villen, J., Shin, C., Camargo, F. D., Gygi, S. P., and Bartel, D. P. (2008). The impact of microRNAs on protein output. Nature 455, 64-71. doi: 10.1038/nature07242
    • (2008) Nature , vol.455 , pp. 64-71
    • Baek, D.1    Villen, J.2    Shin, C.3    Camargo, F.D.4    Gygi, S.P.5    Bartel, D.P.6
  • 8
    • 84860279695 scopus 로고    scopus 로고
    • MicroRNA let-7i is a promising serum biomarker for blast-induced traumatic brain injury
    • doi: 10.1089/neu.2011.2146
    • Balakathiresan, N., Bhomia, M., Chandran, R., Chavko, M., Mccarron, R. M., and Maheshwari, R. K. (2012). MicroRNA let-7i is a promising serum biomarker for blast-induced traumatic brain injury. J. Neurotrauma 29, 1379-1387. doi: 10.1089/neu.2011.2146
    • (2012) J. Neurotrauma , vol.29 , pp. 1379-1387
    • Balakathiresan, N.1    Bhomia, M.2    Chandran, R.3    Chavko, M.4    McCarron, R.M.5    Maheshwari, R.K.6
  • 9
    • 84866047835 scopus 로고    scopus 로고
    • MicroRNAs in cerebrospinal fluid as biomarker for disease course monitoring in primary central nervous system lymphoma
    • doi: 10.1007/s11060-012-0908-2
    • Baraniskin, A., Kuhnhenn, J., Schlegel, U., Schmiegel, W., Hahn, S., and Schroers, R. (2012). MicroRNAs in cerebrospinal fluid as biomarker for disease course monitoring in primary central nervous system lymphoma. J. Neurooncol. 109, 239-244. doi: 10.1007/s11060-012-0908-2
    • (2012) J. Neurooncol , vol.109 , pp. 239-244
    • Baraniskin, A.1    Kuhnhenn, J.2    Schlegel, U.3    Schmiegel, W.4    Hahn, S.5    Schroers, R.6
  • 10
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • doi: 10.1016/S0092-8674(04)00045-5
    • Bartel, D. P. (2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297. doi: 10.1016/S0092-8674(04)00045-5
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 11
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • doi: 10.1016/j.cell.2009.01.002
    • Bartel, D. P. (2009). MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233. doi: 10.1016/j.cell.2009.01.002
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 12
    • 84877308887 scopus 로고    scopus 로고
    • The DEAH-box helicase DHX36 mediates dendritic localization of the neuronal precursor-microRNA-134
    • doi: 10.1101/gad.211243.112
    • Bicker, S., Khudayberdiev, S., Weiss, K., Zocher, K., Baumeister, S., and Schratt, G. (2013). The DEAH-box helicase DHX36 mediates dendritic localization of the neuronal precursor-microRNA-134. Genes Dev. 27, 991-996. doi: 10.1101/gad.211243.112
    • (2013) Genes Dev , vol.27 , pp. 991-996
    • Bicker, S.1    Khudayberdiev, S.2    Weiss, K.3    Zocher, K.4    Baumeister, S.5    Schratt, G.6
  • 13
    • 84876386633 scopus 로고    scopus 로고
    • Assessing sample and miRNA profile quality in serum and plasma or other biofluids
    • doi: 10.1016/j.ymeth.2012.09.015
    • Blondal, T., Jensby Nielsen, S., Baker, A., Andreasen, D., Mouritzen, P., Wrang Teilum, M., et al. (2013). Assessing sample and miRNA profile quality in serum and plasma or other biofluids. Methods 59, S1-S6. doi: 10.1016/j.ymeth.2012.09.015
    • (2013) Methods , vol.59
    • Blondal, T.1    Jensby, N.S.2    Baker, A.3    Andreasen, D.4    Mouritzen, P.5    Wrang, T.M.6
  • 14
    • 33845370280 scopus 로고    scopus 로고
    • RNA polymerase III transcribes human microRNAs
    • doi: 10.1038/nsmb1167
    • Borchert, G. M., Lanier, W., and Davidson, B. L. (2006). RNA polymerase III transcribes human microRNAs. Nat. Struct. Mol. Biol. 13, 1097-1101. doi: 10.1038/nsmb1167
    • (2006) Nat. Struct. Mol. Biol , vol.13 , pp. 1097-1101
    • Borchert, G.M.1    Lanier, W.2    Davidson, B.L.3
  • 15
    • 84855189193 scopus 로고    scopus 로고
    • Cell signaling underlying epileptic behavior
    • doi: 10.3389/fnbeh.2011.00045
    • Bozzi, Y., Dunleavy, M., and Henshall, D. C. (2011). Cell signaling underlying epileptic behavior. Front. Behav. Neurosci. 5:45. doi: 10.3389/fnbeh.2011.00045
    • (2011) Front. Behav. Neurosci , vol.5 , pp. 45
    • Bozzi, Y.1    Dunleavy, M.2    Henshall, D.C.3
  • 16
    • 67651087321 scopus 로고    scopus 로고
    • Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications
    • doi: 10.1038/nrg2628
    • Brown, B. D., and Naldini, L. (2009). Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications. Nat. Rev. Genet. 10, 578-585. doi: 10.1038/nrg2628
    • (2009) Nat. Rev. Genet , vol.10 , pp. 578-585
    • Brown, B.D.1    Naldini, L.2
  • 17
    • 49349115993 scopus 로고    scopus 로고
    • RNAi-mediated reversible opening of the blood-brain barrier
    • doi: 10.1002/jgm.1211
    • Campbell, M., Kiang, A. S., Kenna, P. F., Kerskens, C., Blau, C., O'Dwyer, L., et al. (2008). RNAi-mediated reversible opening of the blood-brain barrier. J. Gene Med. 10, 930-947. doi: 10.1002/jgm.1211
    • (2008) J. Gene Med , vol.10 , pp. 930-947
    • Campbell, M.1    Kiang, A.S.2    Kenna, P.F.3    Kerskens, C.4    Blau, C.5    O'Dwyer, L.6
  • 18
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • doi: 10.1158/0008-5472.CAN-05-0137
    • Chan, J. A., Krichevsky, A. M., and Kosik, K. S. (2005). MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res. 65, 6029-6033. doi: 10.1158/0008-5472.CAN-05-0137
    • (2005) Cancer Res , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 19
    • 34249817549 scopus 로고    scopus 로고
    • Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
    • doi: 10.1016/j.molcel.2007.05.010
    • Chang, T. C., Wentzel, E. A., Kent, O. A., Ramachandran, K., Mullendore, M., Lee, K. H., et al. (2007). Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol. Cell. 26, 745-752. doi: 10.1016/j.molcel.2007.05.010
    • (2007) Mol. Cell , vol.26 , pp. 745-752
    • Chang, T.C.1    Wentzel, E.A.2    Kent, O.A.3    Ramachandran, K.4    Mullendore, M.5    Lee, K.H.6
  • 20
    • 53349177819 scopus 로고    scopus 로고
    • Characterization of microRNAs in serum: A novel class of biomarkers for diagnosis of cancer and other diseases
    • doi: 10.1038/cr.2008.282
    • Chen, X., Ba, Y., Ma, L., Cai, X., Yin, Y., Wang, K., et al. (2008). Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res. 18, 997-1006. doi: 10.1038/cr.2008.282
    • (2008) Cell Res , vol.18 , pp. 997-1006
    • Chen, X.1    Ba, Y.2    Ma, L.3    Cai, X.4    Yin, Y.5    Wang, K.6
  • 21
    • 32544434351 scopus 로고    scopus 로고
    • Status epilepticus: Pathophysiology and management in adults
    • doi: 10.1016/S14744422(06)70374-X
    • Chen, J. W., and Wasterlain, C. G. (2006). Status epilepticus: pathophysiology and management in adults. Lancet Neurol. 5, 246-256. doi: 10.1016/S14744422(06)70374-X
    • (2006) Lancet Neurol , vol.5 , pp. 246-256
    • Chen, J.W.1    Wasterlain, C.G.2
  • 22
    • 67749132423 scopus 로고    scopus 로고
    • Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps
    • doi: 10.1038/nature08170
    • Chi, S. W., Zang, J. B., Mele, A., and Darnell, R. B. (2009). Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 460, 479-486. doi: 10.1038/nature08170
    • (2009) Nature , vol.460 , pp. 479-486
    • Chi, S.W.1    Zang, J.B.2    Mele, A.3    Darnell, R.B.4
  • 23
    • 58149401820 scopus 로고    scopus 로고
    • Dendrites of mammalian neurons contain specialized P-body-like structures that respond to neuronal activation
    • doi: 10.1523/JNEUROSCI.4155-08.2008
    • Cougot, N., Bhattacharyya, S. N., Tapia-Arancibia, L., Bordonne, R., Filipowicz, W., Bertrand, E., et al. (2008). Dendrites of mammalian neurons contain specialized P-body-like structures that respond to neuronal activation. J. Neurosci. 28, 13793-13804. doi: 10.1523/JNEUROSCI.4155-08.2008
    • (2008) J. Neurosci , vol.28 , pp. 13793-13804
    • Cougot, N.1    Bhattacharyya, S.N.2    Tapia-Arancibia, L.3    Bordonne, R.4    Filipowicz, W.5    Bertrand, E.6
  • 24
    • 0032770526 scopus 로고    scopus 로고
    • Chronic epileptogenic cellular alterations in the limbic system after status epilepticus
    • doi: 10.1111/j.1528-1157.1999.tb00875.x
    • Coulter, D. A. (1999). Chronic epileptogenic cellular alterations in the limbic system after status epilepticus. Epilepsia 40, S23-S33. doi: 10.1111/j.1528-1157.1999.tb00875.x
    • (1999) Epilepsia , vol.40
    • Coulter, D.A.1
  • 25
    • 79959546069 scopus 로고    scopus 로고
    • Analytical aspects of microRNA in diagnostics: A review
    • doi: 10.1016/j.aca.2011.05.025
    • de Planell-Saguer, M., and Rodicio, M. C. (2011). Analytical aspects of microRNA in diagnostics: a review. Anal. Chim. Acta 699, 134-152. doi: 10.1016/j.aca.2011.05.025
    • (2011) Anal. Chim. Acta , vol.699 , pp. 134-152
    • de Planell-Saguer, M.1    Rodicio, M.C.2
  • 26
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells
    • doi: 10.1038/nmeth1079
    • Ebert, M. S., Neilson, J. R., and Sharp, P. A. (2007). MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat. Methods 4, 721-726. doi: 10.1038/nmeth1079
    • (2007) Nat. Methods , vol.4 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 27
    • 84860324470 scopus 로고    scopus 로고
    • Roles for microRNAs in conferring robustness to biological processes
    • doi: 10.1016/j.cell.2012. 04.005
    • Ebert, M. S., and Sharp, P. A. (2012). Roles for microRNAs in conferring robustness to biological processes. Cell 149, 515-524. doi: 10.1016/j.cell.2012. 04.005
    • (2012) Cell , vol.149 , pp. 515-524
    • Ebert, M.S.1    Sharp, P.A.2
  • 28
    • 75949101467 scopus 로고    scopus 로고
    • Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132
    • doi: 10.1016/j.neuron.2010.01.005
    • Edbauer, D., Neilson, J. R., Foster, K. A., Wang, C. F., Seeburg, D. P., Batterton, M. N., et al. (2010). Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132. Neuron 65, 373-384. doi: 10.1016/j.neuron.2010.01.005
    • (2010) Neuron , vol.65 , pp. 373-384
    • Edbauer, D.1    Neilson, J.R.2    Foster, K.A.3    Wang, C.F.4    Seeburg, D.P.5    Batterton, M.N.6
  • 29
    • 42249093319 scopus 로고    scopus 로고
    • LNA-mediated microRNA silencing in non-human primates
    • doi: 10.1038/nature06783
    • Elmen, J., Lindow, M., Schutz, S., Lawrence, M., Petri, A., Obad, S., et al. (2008). LNA-mediated microRNA silencing in non-human primates. Nature 452, 896-899. doi: 10.1038/nature06783
    • (2008) Nature , vol.452 , pp. 896-899
    • Elmen, J.1    Lindow, M.2    Schutz, S.3    Lawrence, M.4    Petri, A.5    Obad, S.6
  • 30
    • 76749107731 scopus 로고    scopus 로고
    • Apoptosis, Bcl-2 family proteins and caspases: The ABCs of seizure-damage and epileptogenesis
    • Engel, T., and Henshall, D. C. (2009). Apoptosis, Bcl-2 family proteins and caspases: the ABCs of seizure-damage and epileptogenesis? Int. J. Physiol. Pathophysiol. Pharmacol. 1, 97-115.
    • (2009) Int. J. Physiol. Pathophysiol. Pharmacol , vol.1 , pp. 97-115
    • Engel, T.1    Henshall, D.C.2
  • 31
    • 77952305771 scopus 로고    scopus 로고
    • Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma
    • doi: 10.1096/fj.09-145870
    • Engel, T., Murphy, B. M., Hatazaki, S., Jimenez-Mateos, E. M., Concannon, C. G., Woods, I., et al. (2010). Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma. FASEB J. 24, 853-861. doi: 10.1096/fj.09-145870
    • (2010) FASEB J , vol.24 , pp. 853-861
    • Engel, T.1    Murphy, B.M.2    Hatazaki, S.3    Jimenez-Mateos, E.M.4    Concannon, C.G.5    Woods, I.6
  • 33
    • 84874322294 scopus 로고    scopus 로고
    • CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures
    • doi: 10.1093/brain/aws337
    • Engel, T., Sanz-Rodgriguez, A., Jimenez-Mateos, E. M., Concannon, C. G., Jimenez-Pacheco, A., Moran, C., et al. (2013b). CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizures. Brain 136, 577-592. doi: 10.1093/brain/aws337
    • (2013) Brain , vol.136 , pp. 577-592
    • Engel, T.1    Sanz-Rodgriguez, A.2    Jimenez-Mateos, E.M.3    Concannon, C.G.4    Jimenez-Pacheco, A.5    Moran, C.6
  • 34
    • 77953629046 scopus 로고    scopus 로고
    • Regulation of mRNA translation and stability by microRNAs
    • doi: 10.1146/annurev-biochem-060308-103103
    • Fabian, M. R., Sonenberg, N., and Filipowicz, W. (2010). Regulation of mRNA translation and stability by microRNAs. Annu. Rev. Biochem. 79, 351-379. doi: 10.1146/annurev-biochem-060308-103103
    • (2010) Annu. Rev. Biochem , vol.79 , pp. 351-379
    • Fabian, M.R.1    Sonenberg, N.2    Filipowicz, W.3
  • 35
    • 84862173056 scopus 로고    scopus 로고
    • MiR-34a represses Numbl in murine neural progenitor cells and antagonizes neuronal differentiation
    • doi: 10.1371/journal.pone. 0038562
    • Fineberg, S. K., Datta, P., Stein, C. S., and Davidson, B. L. (2012). MiR-34a represses Numbl in murine neural progenitor cells and antagonizes neuronal differentiation. PLoS ONE 7:e38562. doi: 10.1371/journal.pone. 0038562
    • (2012) PLoS ONE , vol.7
    • Fineberg, S.K.1    Datta, P.2    Stein, C.S.3    Davidson, B.L.4
  • 36
    • 62649086993 scopus 로고    scopus 로고
    • Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels
    • doi: 10.1038/emboj.2009.10
    • Fiore, R., Khudayberdiev, S., Christensen, M., Siegel, G., Flavell, S. W., Kim, T. K., et al. (2009). Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels. EMBO J. 28, 697-710. doi: 10.1038/emboj.2009.10
    • (2009) EMBO J , vol.28 , pp. 697-710
    • Fiore, R.1    Khudayberdiev, S.2    Christensen, M.3    Siegel, G.4    Flavell, S.W.5    Kim, T.K.6
  • 37
    • 79958782004 scopus 로고    scopus 로고
    • MicroRNAs 10a and 10b are potent inducers of neuroblastoma cell differentiation through targeting of nuclear receptor corepressor 2
    • doi: 10.1038/cdd.2010.172
    • Foley, N. H., Bray, I., Watters, K. M., Das, S., Bryan, K., Bernas, T., et al. (2011). MicroRNAs 10a and 10b are potent inducers of neuroblastoma cell differentiation through targeting of nuclear receptor corepressor 2. Cell Death Differ. 18, 1089-1098. doi: 10.1038/cdd.2010.172
    • (2011) Cell Death Differ , vol.18 , pp. 1089-1098
    • Foley, N.H.1    Bray, I.2    Watters, K.M.3    Das, S.4    Bryan, K.5    Bernas, T.6
  • 38
    • 34848926206 scopus 로고    scopus 로고
    • Cholinergic dysfunction in temporal lobe epilepsy
    • doi: 10.1111/j.1528-1167.2007.01300.x
    • Friedman, A., Behrens, C. J., and Heinemann, U. (2007). Cholinergic dysfunction in temporal lobe epilepsy. Epilepsia 48(Suppl. 5), 126-130. doi: 10.1111/j.1528-1167.2007.01300.x
    • (2007) Epilepsia , vol.48 , Issue.5 SUPPL. , pp. 126-130
    • Friedman, A.1    Behrens, C.J.2    Heinemann, U.3
  • 39
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • doi: 10.1101/gr.082701.108
    • Friedman, R. C., Farh, K. K., Burge, C. B., and Bartel, D. P. (2009). Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 19, 92-105. doi: 10.1101/gr.082701.108
    • (2009) Genome Res , vol.19 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3    Bartel, D.P.4
  • 40
    • 34247168832 scopus 로고    scopus 로고
    • Neuroprotective strategies in status epilepticus
    • eds C. G. Wasterlain and D. M. Treiman (Cambridge: MIT Press
    • Fujikawa, D. G. (2006). Neuroprotective strategies in status epilepticus, in Status Epilepticus: Mechanisms and Management, eds C. G. Wasterlain and D. M. Treiman (Cambridge: MIT Press), 463-480.
    • (2006) Status Epilepticus: Mechanisms and Management , pp. 463-480
    • Fujikawa, D.G.1
  • 41
    • 84857968441 scopus 로고    scopus 로고
    • The majority of microRNAs detectable in serum and saliva is concentrated in exosomes
    • doi: 10.1371/journal.pone.0030679
    • Gallo, A., Tandon, M., Alevizos, I., and Illei, G. G. (2012). The majority of microRNAs detectable in serum and saliva is concentrated in exosomes. PLoS ONE 7:e30679. doi: 10.1371/journal.pone.0030679
    • (2012) PLoS ONE , vol.7
    • Gallo, A.1    Tandon, M.2    Alevizos, I.3    Illei, G.G.4
  • 42
    • 84881141692 scopus 로고    scopus 로고
    • Intravenous ketamine for the treatment of refractory status epilepticus: A retrospective multicenter study
    • doi: 10.1111/epi.12247
    • Gaspard, N., Foreman, B., Judd, L. M., Brenton, J. N., Nathan, B. R., Mccoy, B. M., et al. (2013). Intravenous ketamine for the treatment of refractory status epilepticus: a retrospective multicenter study. Epilepsia 54, 1498-1503. doi: 10.1111/epi.12247
    • (2013) Epilepsia , vol.54 , pp. 1498-1503
    • Gaspard, N.1    Foreman, B.2    Judd, L.M.3    Brenton, J.N.4    Nathan, B.R.5    McCoy, B.M.6
  • 43
    • 33751099302 scopus 로고    scopus 로고
    • Potential new antiepileptogenic targets indicated by microarray analysis in a rat model for temporal lobe epilepsy
    • doi: 10.1523/JNEUROSCI.2766-06.2006
    • Gorter, J. A., Van Vliet, E. A., Aronica, E., Breit, T., Rauwerda, H., Lopes Da Silva, F. H., et al. (2006). Potential new antiepileptogenic targets indicated by microarray analysis in a rat model for temporal lobe epilepsy. J. Neurosci. 26, 11083-11110. doi: 10.1523/JNEUROSCI.2766-06.2006
    • (2006) J. Neurosci , vol.26 , pp. 11083-11110
    • Gorter, J.A.1    van Vliet, E.A.2    Aronica, E.3    Breit, T.4    Rauwerda, H.5    Lopes Da Silva, F.H.6
  • 44
    • 9144225636 scopus 로고    scopus 로고
    • The microprocessor complex mediates the genesis of microRNAs
    • doi: 10.1038/nature03120
    • Gregory, R. I., Yan, K. P., Amuthan, G., Chendrimada, T., Doratotaj, B., Cooch, N., et al. (2004). The microprocessor complex mediates the genesis of microRNAs. Nature 432, 235-240. doi: 10.1038/nature03120
    • (2004) Nature , vol.432 , pp. 235-240
    • Gregory, R.I.1    Yan, K.P.2    Amuthan, G.3    Chendrimada, T.4    Doratotaj, B.5    Cooch, N.6
  • 45
    • 77955644289 scopus 로고    scopus 로고
    • Mammalian microRNAs predominantly act to decrease target mRNA levels
    • doi: 10.1038/nature09267
    • Guo, H., Ingolia, N. T., Weissman, J. S., and Bartel, D. P. (2010). Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466, 835-840. doi: 10.1038/nature09267
    • (2010) Nature , vol.466 , pp. 835-840
    • Guo, H.1    Ingolia, N.T.2    Weissman, J.S.3    Bartel, D.P.4
  • 46
    • 84871297324 scopus 로고    scopus 로고
    • Regulated microRNAs in the CSF of patients with multiple sclerosis: A case-control study
    • doi: 10.1212/WNL.0b013e3182759621
    • Haghikia, A., Hellwig, K., Baraniskin, A., Holzmann, A., Decard, B. F., Thum, T., et al. (2012). Regulated microRNAs in the CSF of patients with multiple sclerosis: a case-control study. Neurology 79, 2166-2170. doi: 10.1212/WNL.0b013e3182759621
    • (2012) Neurology , vol.79 , pp. 2166-2170
    • Haghikia, A.1    Hellwig, K.2    Baraniskin, A.3    Holzmann, A.4    Decard, B.F.5    Thum, T.6
  • 47
    • 78649739197 scopus 로고    scopus 로고
    • Transgenic miR132 alters neuronal spine density and impairs novel object recognition memory
    • doi: 10.1371/journal.pone.0015497
    • Hansen, K. F., Sakamoto, K., Wayman, G. A., Impey, S., and Obrietan, K. (2010). Transgenic miR132 alters neuronal spine density and impairs novel object recognition memory. PLoS ONE 5:e15497. doi: 10.1371/journal.pone.0015497
    • (2010) PLoS ONE , vol.5
    • Hansen, K.F.1    Sakamoto, K.2    Wayman, G.A.3    Impey, S.4    Obrietan, K.5
  • 48
    • 84862922523 scopus 로고    scopus 로고
    • Cell-type-based analysis of microRNA profiles in the mouse brain
    • doi: 10.1016/j.neuron.2011.11.010
    • He, M., Liu, Y., Wang, X., Zhang, M. Q., Hannon, G. J., and Huang, Z. J. (2012). Cell-type-based analysis of microRNA profiles in the mouse brain. Neuron 73, 35-48. doi: 10.1016/j.neuron.2011.11.010
    • (2012) Neuron , vol.73 , pp. 35-48
    • He, M.1    Liu, Y.2    Wang, X.3    Zhang, M.Q.4    Hannon, G.J.5    Huang, Z.J.6
  • 49
    • 20444467290 scopus 로고    scopus 로고
    • A microRNA polycistron as a potential human oncogene
    • doi: 10.1038/nature03552
    • He, L., Thomson, J. M., Hemann, M. T., Hernando-Monge, E., Mu, D., Goodson, S., et al. (2005). A microRNA polycistron as a potential human oncogene. Nature 435, 828-833. doi: 10.1038/nature03552
    • (2005) Nature , vol.435 , pp. 828-833
    • He, L.1    Thomson, J.M.2    Hemann, M.T.3    Hernando-Monge, E.4    Mu, D.5    Goodson, S.6
  • 50
    • 84879708097 scopus 로고    scopus 로고
    • Contribution of apoptosis-associated signaling pathways to epileptogenesis: Lessons from Bcl-2 family knockouts
    • doi: 10.3389/fncel.2013.00110
    • Henshall, D. C., and Engel, T. (2013). Contribution of apoptosis-associated signaling pathways to epileptogenesis: lessons from Bcl-2 family knockouts. Front. Cell Neurosci. 7:110. doi: 10.3389/fncel.2013.00110.
    • (2013) Front. Cell Neurosci , vol.7 , pp. 110
    • Henshall, D.C.1    Engel, T.2
  • 51
    • 74249123570 scopus 로고    scopus 로고
    • The miR-34 family in cancer and apoptosis
    • doi: 10.1038/cdd.2009.56
    • Hermeking, H. (2010). The miR-34 family in cancer and apoptosis. Cell Death Differ. 17, 193-199. doi: 10.1038/cdd.2009.56
    • (2010) Cell Death Differ , vol.17 , pp. 193-199
    • Hermeking, H.1
  • 52
    • 84866481943 scopus 로고    scopus 로고
    • MicroRNA expression profile of the hippocampus in a rat model of temporal lobe epilepsy and miR-34a-targeted neuroprotection against hippocampal neurone cell apoptosis post-status epilepticus
    • doi: 10.1186/14712202-13-115
    • Hu, K., Xie, Y. Y., Zhang, C., Ouyang, D. S., Long, H. Y., Sun, D. N., et al. (2012). MicroRNA expression profile of the hippocampus in a rat model of temporal lobe epilepsy and miR-34a-targeted neuroprotection against hippocampal neurone cell apoptosis post-status epilepticus. BMC Neurosci. 13:115. doi: 10.1186/14712202-13-115
    • (2012) BMC Neurosci , vol.13 , pp. 115
    • Hu, K.1    Xie, Y.Y.2    Zhang, C.3    Ouyang, D.S.4    Long, H.Y.5    Sun, D.N.6
  • 53
    • 78650837680 scopus 로고    scopus 로고
    • Expression profile of microRNAs in rat hippocampus following lithium-pilocarpine-induced status epilepticus
    • doi: 10.1016/j.neulet.2010. 11.040
    • Hu, K., Zhang, C., Long, L., Long, X., Feng, L., Li, Y., et al. (2011). Expression profile of microRNAs in rat hippocampus following lithium-pilocarpine-induced status epilepticus. Neurosci. Lett. 488, 252-257. doi: 10.1016/j.neulet.2010. 11.040
    • (2011) Neurosci. Lett , vol.488 , pp. 252-257
    • Hu, K.1    Zhang, C.2    Long, L.3    Long, X.4    Feng, L.5    Li, Y.6
  • 54
    • 57849130395 scopus 로고    scopus 로고
    • Detection of microRNA expression in human peripheral blood microvesicles
    • doi: 10.1371/journal.pone.0003694
    • Hunter, M. P., Ismail, N., Zhang, X., Aguda, B. D., Lee, E. J., Yu, L., et al. (2008). Detection of microRNA expression in human peripheral blood microvesicles. PLoS ONE 3:e3694. doi: 10.1371/journal.pone.0003694
    • (2008) PLoS ONE , vol.3
    • Hunter, M.P.1    Ismail, N.2    Zhang, X.3    Aguda, B.D.4    Lee, E.J.5    Yu, L.6
  • 55
    • 84879604742 scopus 로고    scopus 로고
    • Evidence for miR-181 involvement in neuroinflammatory responses of astrocytes
    • doi: 10.1002/glia.22483
    • Hutchison, E. R., Kawamoto, E. M., Taub, D. D., Lal, A., Abdelmohsen, K., Zhang, Y., et al. (2013). Evidence for miR-181 involvement in neuroinflammatory responses of astrocytes. Glia 61, 1018-28. doi: 10.1002/glia.22483
    • (2013) Glia , vol.61 , pp. 1018-1028
    • Hutchison, E.R.1    Kawamoto, E.M.2    Taub, D.D.3    Lal, A.4    Abdelmohsen, K.5    Zhang, Y.6
  • 56
    • 84866369867 scopus 로고    scopus 로고
    • MicroRNA-146a: A key regulator of astrocyte-mediated inflammatory response
    • doi: 10.1371/journal.pone.0044789
    • Iyer, A., Zurolo, E., Prabowo, A., Fluiter, K., Spliet, W. G., Van Rijen, P. C., et al. (2012). MicroRNA-146a: a key regulator of astrocyte-mediated inflammatory response. PLoS ONE 7:e44789. doi: 10.1371/journal.pone.0044789
    • (2012) PLoS ONE , vol.7
    • Iyer, A.1    Zurolo, E.2    Prabowo, A.3    Fluiter, K.4    Spliet, W.G.5    van Rijen, P.C.6
  • 58
    • 80054998780 scopus 로고    scopus 로고
    • miRNA Expression profile after status epilepticus and hippocampal neuroprotection by targeting miR-132
    • doi: 10.1016/j.ajpath.2011.07.036
    • Jimenez-Mateos, E. M., Bray, I., Sanz-Rodriguez, A., Engel, T., Mckiernan, R. C., Mouri, G., et al. (2011). miRNA Expression profile after status epilepticus and hippocampal neuroprotection by targeting miR-132. Am. J. Pathol. 179, 2519-2532. doi: 10.1016/j.ajpath.2011.07.036
    • (2011) Am. J. Pathol , vol.179 , pp. 2519-2532
    • Jimenez-Mateos, E.M.1    Bray, I.2    Sanz-Rodriguez, A.3    Engel, T.4    McKiernan, R.C.5    Mouri, G.6
  • 59
    • 84863715734 scopus 로고    scopus 로고
    • Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects
    • doi: 10.1038/nm.2834
    • Jimenez-Mateos, E. M., Engel, T., Merino-Serrais, P., Mckiernan, R. C., Tanaka, K., Mouri, G., et al. (2012). Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects. Nat. Med. 18, 1087-1094. doi: 10.1038/nm.2834
    • (2012) Nat. Med , vol.18 , pp. 1087-1094
    • Jimenez-Mateos, E.M.1    Engel, T.2    Merino-Serrais, P.3    McKiernan, R.C.4    Tanaka, K.5    Mouri, G.6
  • 60
    • 56349130733 scopus 로고    scopus 로고
    • Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways
    • doi: 10.1016/j.nbd.2008.08.008
    • Jimenez-Mateos, E. M., Hatazaki, S., Johnson, M. B., Bellver-Estelles, C., Mouri, G., Bonner, C., et al. (2008). Hippocampal transcriptome after status epilepticus in mice rendered seizure damage-tolerant by epileptic preconditioning features suppressed calcium and neuronal excitability pathways. Neurobiol. Dis. 32, 442-453. doi: 10.1016/j.nbd.2008.08.008
    • (2008) Neurobiol. Dis , vol.32 , pp. 442-453
    • Jimenez-Mateos, E.M.1    Hatazaki, S.2    Johnson, M.B.3    Bellver-Estelles, C.4    Mouri, G.5    Bonner, C.6
  • 61
    • 84877092851 scopus 로고    scopus 로고
    • Comprehensive expression analyses of neural cell-type-specific miRNAs identify new determinants of the specification and maintenance of neuronal phenotypes
    • doi: 10.1523/JNEUROSCI.0600-12.2013
    • Jovicic, A., Roshan, R., Moisoi, N., Pradervand, S., Moser, R., Pillai, B., et al. (2013). Comprehensive expression analyses of neural cell-type-specific miRNAs identify new determinants of the specification and maintenance of neuronal phenotypes. J. Neurosci. 33, 5127-5137. doi: 10.1523/JNEUROSCI.0600-12.2013
    • (2013) J. Neurosci , vol.33 , pp. 5127-5137
    • Jovicic, A.1    Roshan, R.2    Moisoi, N.3    Pradervand, S.4    Moser, R.5    Pillai, B.6
  • 62
    • 0141631876 scopus 로고    scopus 로고
    • A microRNA array reveals extensive regulation of microRNAs during brain development
    • doi: 10.1261/rna.5980303
    • Krichevsky, A. M., King, K. S., Donahue, C. P., Khrapko, K., and Kosik, K. S. (2003). A microRNA array reveals extensive regulation of microRNAs during brain development. RNA 9, 1274-1281. doi: 10.1261/rna.5980303
    • (2003) RNA , vol.9 , pp. 1274-1281
    • Krichevsky, A.M.1    King, K.S.2    Donahue, C.P.3    Khrapko, K.4    Kosik, K.S.5
  • 63
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • doi: 10.1038/nrg2843
    • Krol, J., Loedige, I., and Filipowicz, W. (2010). The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 11, 597-610. doi: 10.1038/nrg2843
    • (2010) Nat. Rev. Genet , vol.11 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 64
    • 28444469246 scopus 로고    scopus 로고
    • Silencing of microRNAs in vivo with 'antagomirs'
    • doi: 10.1038/nature04303
    • Krutzfeldt, J., Rajewsky, N., Braich, R., Rajeev, K. G., Tuschl, T., Manoharan, M., et al. (2005). Silencing of microRNAs in vivo with 'antagomirs'. Nature 438, 685-689. doi: 10.1038/nature04303
    • (2005) Nature , vol.438 , pp. 685-689
    • Krutzfeldt, J.1    Rajewsky, N.2    Braich, R.3    Rajeev, K.G.4    Tuschl, T.5    Manoharan, M.6
  • 65
    • 58149232589 scopus 로고    scopus 로고
    • How do seizures stop?
    • doi: 10.1111/j.1528-1167.2008.01669.x
    • Lado, F. A., and Moshe, S. L. (2008). How do seizures stop? Epilepsia 49, 1651-1664. doi: 10.1111/j.1528-1167.2008.01669.x
    • (2008) Epilepsia , vol.49 , pp. 1651-1664
    • Lado, F.A.1    Moshe, S.L.2
  • 66
    • 0037197803 scopus 로고    scopus 로고
    • Identification of tissue-specific microRNAs from mouse
    • doi: 10.1016/S0960-9822(02)00809-6
    • Lagos-Quintana, M., Rauhut, R., Yalcin, A., Meyer, J., Lendeckel, W., and Tuschl, T. (2002). Identification of tissue-specific microRNAs from mouse. Curr. Biol. 12, 735-739. doi: 10.1016/S0960-9822(02)00809-6
    • (2002) Curr. Biol , vol.12 , pp. 735-739
    • Lagos-Quintana, M.1    Rauhut, R.2    Yalcin, A.3    Meyer, J.4    Lendeckel, W.5    Tuschl, T.6
  • 67
    • 77956270890 scopus 로고    scopus 로고
    • Transcriptome analysis of the hippocampal CA1 pyramidal cell region after kainic acid-induced status epilepticus in juvenile rats
    • doi: 10.1371/journal.pone.0010733
    • Lauren, H. B., Lopez-Picon, F. R., Brandt, A. M., Rios-Rojas, C. J., and Holopainen, I. E. (2010). Transcriptome analysis of the hippocampal CA1 pyramidal cell region after kainic acid-induced status epilepticus in juvenile rats. PLoS ONE 5:e10733. doi: 10.1371/journal.pone.0010733
    • (2010) PLoS ONE , vol.5
    • Lauren, H.B.1    Lopez-Picon, F.R.2    Brandt, A.M.3    Rios-Rojas, C.J.4    Holopainen, I.E.5
  • 68
    • 64349101658 scopus 로고    scopus 로고
    • MicroRNA-125b is a novel negative regulator of p53
    • doi: 10.1101/gad.1767609
    • Le, M. T., Teh, C., Shyh-Chang, N., Xie, H., Zhou, B., Korzh, V., et al. (2009). MicroRNA-125b is a novel negative regulator of p53. Genes Dev. 23, 862-876. doi: 10.1101/gad.1767609
    • (2009) Genes Dev , vol.23 , pp. 862-876
    • Le, M.T.1    Teh, C.2    Shyh-Chang, N.3    Xie, H.4    Zhou, B.5    Korzh, V.6
  • 69
    • 0141843656 scopus 로고    scopus 로고
    • The nuclear RNase III Drosha initiates microRNA processing
    • doi: 10.1038/nature01957
    • Lee, Y., Ahn, C., Han, J., Choi, H., Kim, J., Yim, J., et al. (2003). The nuclear RNase III Drosha initiates microRNA processing. Nature 425, 415-419. doi: 10.1038/nature01957
    • (2003) Nature , vol.425 , pp. 415-419
    • Lee, Y.1    Ahn, C.2    Han, J.3    Choi, H.4    Kim, J.5    Yim, J.6
  • 70
    • 59449090590 scopus 로고    scopus 로고
    • The CREB/CRE transcriptional pathway: Protection against oxidative stress-mediated neuronal cell death
    • doi: 10.1111/j.1471-4159.2008.05864.x
    • Lee, B., Cao, R., Choi, Y. S., Cho, H. Y., Rhee, A. D., Hah, C. K., et al. (2009). The CREB/CRE transcriptional pathway: protection against oxidative stress-mediated neuronal cell death. J. Neurochem. 108, 1251-1265. doi: 10.1111/j.1471-4159.2008.05864.x
    • (2009) J. Neurochem , vol.108 , pp. 1251-1265
    • Lee, B.1    Cao, R.2    Choi, Y.S.3    Cho, H.Y.4    Rhee, A.D.5    Hah, C.K.6
  • 71
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • doi: 10.1038/sj.emboj.7600385
    • Lee, Y., Kim, M., Han, J., Yeom, K. H., Lee, S., Baek, S. H., et al. (2004). MicroRNA genes are transcribed by RNA polymerase II. EMBO J. 23, 4051-4060. doi: 10.1038/sj.emboj.7600385
    • (2004) EMBO J , vol.23 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3    Yeom, K.H.4    Lee, S.5    Baek, S.H.6
  • 72
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • doi: 10.1038/nature 03315
    • Lim, L. P., Lau, N. C., Garrett-Engele, P., Grimson, A., Schelter, J. M., Castle, J., et al. (2005). Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433, 769-773. doi: 10.1038/nature 03315
    • (2005) Nature , vol.433 , pp. 769-773
    • Lim, L.P.1    Lau, N.C.2    Garrett-Engele, P.3    Grimson, A.4    Schelter, J.M.5    Castle, J.6
  • 73
    • 73949091031 scopus 로고    scopus 로고
    • Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures
    • doi: 10.1038/jcbfm.2009.186
    • Liu, D. Z., Tian, Y., Ander, B. P., Xu, H., Stamova, B. S., Zhan, X., et al. (2010). Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizures. J. Cereb. Blood Flow Metab. 30, 92-101. doi: 10.1038/jcbfm.2009.186
    • (2010) J. Cereb. Blood Flow Metab , vol.30 , pp. 92-101
    • Liu, D.Z.1    Tian, Y.2    Ander, B.P.3    Xu, H.4    Stamova, B.S.5    Zhan, X.6
  • 74
    • 77957337142 scopus 로고    scopus 로고
    • Functional, metabolic, and synaptic changes after seizures as potential targets for antiepileptic therapy
    • doi: 10.1016/j.yebeh.2010.06.035
    • Loscher, W., and Kohling, R. (2010). Functional, metabolic, and synaptic changes after seizures as potential targets for antiepileptic therapy. Epilepsy Behav. 19, 105-113. doi: 10.1016/j.yebeh.2010.06.035
    • (2010) Epilepsy Behav , vol.19 , pp. 105-113
    • Loscher, W.1    Kohling, R.2
  • 75
    • 23844501276 scopus 로고    scopus 로고
    • Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent manner
    • doi: 10.1111/j.1471-4159.2005.03224.x
    • Lugli, G., Larson, J., Martone, M. E., Jones, Y., and Smalheiser, N. R. (2005). Dicer and eIF2c are enriched at postsynaptic densities in adult mouse brain and are modified by neuronal activity in a calpain-dependent manner. J. Neurochem. 94, 896-905. doi: 10.1111/j.1471-4159.2005.03224.x
    • (2005) J. Neurochem , vol.94 , pp. 896-905
    • Lugli, G.1    Larson, J.2    Martone, M.E.3    Jones, Y.4    Smalheiser, N.R.5
  • 76
    • 35748942529 scopus 로고    scopus 로고
    • Gene and protein expression in experimental status epilepticus
    • doi: 10.1111/j.15281167.2007.01342.x
    • Lukasiuk, K., and Pitkanen, A. (2007). Gene and protein expression in experimental status epilepticus. Epilepsia 48(Suppl. 8), 28-32. doi: 10.1111/j.15281167.2007.01342.x
    • (2007) Epilepsia , vol.48 , Issue.8 SUPPL. , pp. 28-32
    • Lukasiuk, K.1    Pitkanen, A.2
  • 77
    • 77950517876 scopus 로고    scopus 로고
    • Ischemic preconditioning regulates expression of microRNAs and a predicted target, MeCP2, in mouse cortex
    • doi: 10.1038/jcbfm.2009.253
    • Lusardi, T. A., Farr, C. D., Faulkner, C. L., Pignataro, G., Yang, T., Lan, J., et al. (2010). Ischemic preconditioning regulates expression of microRNAs and a predicted target, MeCP2, in mouse cortex. J. Cereb. Blood Flow Metab. 30, 744-756. doi: 10.1038/jcbfm.2009.253
    • (2010) J. Cereb. Blood Flow Metab , vol.30 , pp. 744-756
    • Lusardi, T.A.1    Farr, C.D.2    Faulkner, C.L.3    Pignataro, G.4    Yang, T.5    Lan, J.6
  • 78
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • doi: 10.1038/nature06174
    • Ma, L., Teruya-Feldstein, J., and Weinberg, R. A. (2007). Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449, 682-688. doi: 10.1038/nature06174
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 79
    • 78650560147 scopus 로고    scopus 로고
    • microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus
    • doi: 10.1073/pnas.1015691107
    • Magill, S. T., Cambronne, X. A., Luikart, B. W., Lioy, D. T., Leighton, B. H., Westbrook, G.L., et al. (2010). microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus. Proc. Natl. Acad. Sci. U.S.A. 107, 20382-20387. doi: 10.1073/pnas.1015691107
    • (2010) Proc. Natl. Acad. Sci. U.S.A , vol.107 , pp. 20382-20387
    • Magill, S.T.1    Cambronne, X.A.2    Luikart, B.W.3    Lioy, D.T.4    Leighton, B.H.5    Westbrook, G.L.6
  • 80
    • 84869096277 scopus 로고    scopus 로고
    • Blood-brain barrier dysfunction and epilepsy: Pathophysiologic role and therapeutic approaches
    • doi: 10.1111/j.1528-1167.2012.03637.x
    • Marchi, N., Granata, T., Ghosh, C., and Janigro, D. (2012). Blood-brain barrier dysfunction and epilepsy: pathophysiologic role and therapeutic approaches. Epilepsia 53, 1877-1886. doi: 10.1111/j.1528-1167.2012.03637.x
    • (2012) Epilepsia , vol.53 , pp. 1877-1886
    • Marchi, N.1    Granata, T.2    Ghosh, C.3    Janigro, D.4
  • 81
    • 84890114703 scopus 로고    scopus 로고
    • Nrf2 defense pathway: Experimental evidence for its protective role in epilepsy
    • doi: 10.1002/ana.23940 [Epub ahead of print]
    • Mazzuferi, M., Kumar, G., Van Eyll, J., Danis, B., Foerch, P., and Kaminski, R. M. (2013). Nrf2 defense pathway: experimental evidence for its protective role in epilepsy. Ann. Neurol. doi: 10.1002/ana.23940 [Epub ahead of print].
    • (2013) Ann. Neurol
    • Mazzuferi, M.1    Kumar, G.2    van Eyll, J.3    Danis, B.4    Foerch, P.5    Kaminski, R.M.6
  • 82
    • 80052587330 scopus 로고    scopus 로고
    • Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy
    • doi: 10.1002/ana.22479
    • McClelland, S., Flynn, C., Dube, C., Richichi, C., Zha, Q., Ghestem, A., et al. (2011). Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy. Ann. Neurol. 70, 454-464. doi: 10.1002/ana.22479
    • (2011) Ann. Neurol , vol.70 , pp. 454-464
    • McClelland, S.1    Flynn, C.2    Dube, C.3    Richichi, C.4    Zha, Q.5    Ghestem, A.6
  • 83
    • 79957784825 scopus 로고    scopus 로고
    • Analysis of circulating microRNA: Preanalytical and analytical challenges
    • doi: 10.1373/clinchem.2010. 157198
    • McDonald, J. S., Milosevic, D., Reddi, H. V., Grebe, S. K., and Algeciras-Schimnich, A. (2011). Analysis of circulating microRNA: preanalytical and analytical challenges. Clin. Chem. 57, 833-840. doi: 10.1373/clinchem.2010. 157198
    • (2011) Clin. Chem , vol.57 , pp. 833-840
    • McDonald, J.S.1    Milosevic, D.2    Reddi, H.V.3    Grebe, S.K.4    Algeciras-Schimnich, A.5
  • 84
    • 84864796082 scopus 로고    scopus 로고
    • Expression profiling the microRNA response to epileptic preconditioning identifies miR-184 as a modulator of seizure-induced neuronal death
    • doi: 10.1016/j.expneurol.2012.06.029
    • McKiernan, R. C., Jimenez-Mateos, E. M., Sano, T., Bray, I., Stallings, R. L., Simon, R. P., et al. (2012). Expression profiling the microRNA response to epileptic preconditioning identifies miR-184 as a modulator of seizure-induced neuronal death. Exp. Neurol. 237, 346-354. doi: 10.1016/j.expneurol.2012.06.029
    • (2012) Exp. Neurol , vol.237 , pp. 346-354
    • McKiernan, R.C.1    Jimenez-Mateos, E.M.2    Sano, T.3    Bray, I.4    Stallings, R.L.5    Simon, R.P.6
  • 85
    • 84864934256 scopus 로고    scopus 로고
    • MicroRNAs shape the neuronal landscape
    • doi: 10.1016/j.neuron.2012.07.005
    • McNeill, E., and Van Vactor, D. (2012). MicroRNAs shape the neuronal landscape. Neuron 75, 363-379. doi: 10.1016/j.neuron.2012.07.005
    • (2012) Neuron , vol.75 , pp. 363-379
    • McNeill, E.1    van Vactor, D.2
  • 86
    • 0026007064 scopus 로고
    • Excitotoxicity and epileptic brain damage
    • doi: 10.1016/0920-1211(91)90095-W
    • Meldrum, B. (1991). Excitotoxicity and epileptic brain damage. Epilepsy Res. 10, 55-61. doi: 10.1016/0920-1211(91)90095-W
    • (1991) Epilepsy Res , vol.10 , pp. 55-61
    • Meldrum, B.1
  • 87
    • 79952717616 scopus 로고    scopus 로고
    • Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing
    • doi: 10.1073/pnas.1014720108
    • Melo, S., Villanueva, A., Moutinho, C., Davalos, V., Spizzo, R., Ivan, C., et al. (2011). Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. Proc. Natl. Acad. Sci. U.S.A. 108, 4394-4399. doi: 10.1073/pnas.1014720108
    • (2011) Proc. Natl. Acad. Sci. U.S.A , vol.108 , pp. 4394-4399
    • Melo, S.1    Villanueva, A.2    Moutinho, C.3    Davalos, V.4    Spizzo, R.5    Ivan, C.6
  • 88
    • 34548687035 scopus 로고    scopus 로고
    • mir-29 regulates Mcl-1 protein expression and apoptosis
    • doi: 10.1038/sj.onc.1210436
    • Mott, J. L., Kobayashi, S., Bronk, S. F., and Gores, G. J. (2007). mir-29 regulates Mcl-1 protein expression and apoptosis. Oncogene 26, 6133-6140. doi: 10.1038/sj.onc.1210436
    • (2007) Oncogene , vol.26 , pp. 6133-6140
    • Mott, J.L.1    Kobayashi, S.2    Bronk, S.F.3    Gores, G.J.4
  • 89
    • 77950111923 scopus 로고    scopus 로고
    • Neuronal activity rapidly induces transcription of the CREB-regulated microRNA-132, in vivo
    • doi: 10.1002/hipo.20646
    • Nudelman, A. S., Dirocco, D. P., Lambert, T. J., Garelick, M. G., Le, J., Nathanson, N. M., et al. (2010). Neuronal activity rapidly induces transcription of the CREB-regulated microRNA-132, in vivo. Hippocampus 20, 492-498. doi: 10.1002/hipo.20646
    • (2010) Hippocampus , vol.20 , pp. 492-498
    • Nudelman, A.S.1    Dirocco, D.P.2    Lambert, T.J.3    Garelick, M.G.4    Le, J.5    Nathanson, N.M.6
  • 90
    • 79953202455 scopus 로고    scopus 로고
    • Silencing of microRNA families by seed-targeting tiny LNAs
    • doi: 10.1038/ng.786
    • Obad, S., Dos Santos, C. O., Petri, A., Heidenblad, M., Broom, O., Ruse, C., et al. (2011). Silencing of microRNA families by seed-targeting tiny LNAs. Nat. Genet. 43, 371-378. doi: 10.1038/ng.786
    • (2011) Nat. Genet , vol.43 , pp. 371-378
    • Obad, S.1    Dos Santos, C.O.2    Petri, A.3    Heidenblad, M.4    Broom, O.5    Ruse, C.6
  • 91
    • 84863723513 scopus 로고    scopus 로고
    • Interleukin-1beta and microRNA-146a in an immature rat model and children with mesial temporal lobe epilepsy
    • doi: 10.1111/j.1528-1167.2012.03540.x
    • Omran, A., Peng, J., Zhang, C., Xiang, Q. L., Xue, J., Gan, N., et al. (2012). Interleukin-1beta and microRNA-146a in an immature rat model and children with mesial temporal lobe epilepsy. Epilepsia 53, 1215-1224. doi: 10.1111/j.1528-1167.2012.03540.x
    • (2012) Epilepsia , vol.53 , pp. 1215-1224
    • Omran, A.1    Peng, J.2    Zhang, C.3    Xiang, Q.L.4    Xue, J.5    Gan, N.6
  • 92
    • 84858005054 scopus 로고    scopus 로고
    • miR-181 targets multiple Bcl-2 family members and influences apoptosis and mitochondrial function in astrocytes
    • doi: 10.1016/j.mito.2011.09.001
    • Ouyang, Y. B., Lu, Y., Yue, S., and Giffard, R. G. (2012). miR-181 targets multiple Bcl-2 family members and influences apoptosis and mitochondrial function in astrocytes. Mitochondrion 12, 213-219. doi: 10.1016/j.mito.2011.09.001
    • (2012) Mitochondrion , vol.12 , pp. 213-219
    • Ouyang, Y.B.1    Lu, Y.2    Yue, S.3    Giffard, R.G.4
  • 93
    • 78650179351 scopus 로고    scopus 로고
    • Niemann-Pick type C fibroblasts have a distinct microRNA profile related to lipid metabolism and certain cellular components
    • doi: 10.1016/j.bbrc.2010.11.026
    • Ozsait, B., Komurcu-Bayrak, E., Levula, M., Erginel-Unaltuna, N., Kahonen, M., Rai, M., et al. (2010). Niemann-Pick type C fibroblasts have a distinct microRNA profile related to lipid metabolism and certain cellular components. Biochem. Biophys. Res. Commun. 403, 316-321. doi: 10.1016/j.bbrc.2010.11.026
    • (2010) Biochem. Biophys. Res. Commun , vol.403 , pp. 316-321
    • Ozsait, B.1    Komurcu-Bayrak, E.2    Levula, M.3    Erginel-Unaltuna, N.4    Kahonen, M.5    Rai, M.6
  • 94
    • 58149215802 scopus 로고    scopus 로고
    • miR-29 miRNAs activate p53 by targeting p85 alpha and CDC42
    • doi: 10.1038/nsmb.1533
    • Park, S. Y., Lee, J. H., Ha, M., Nam, J. W., and Kim, V. N. (2009). miR-29 miRNAs activate p53 by targeting p85 alpha and CDC42. Nat. Struct. Mol. Biol. 16, 23-29. doi: 10.1038/nsmb.1533
    • (2009) Nat. Struct. Mol. Biol , vol.16 , pp. 23-29
    • Park, S.Y.1    Lee, J.H.2    Ha, M.3    Nam, J.W.4    Kim, V.N.5
  • 95
    • 84861653416 scopus 로고    scopus 로고
    • miR-132 enhances dendritic morphogenesis, spine density, synaptic integration, and survival of newborn olfactory bulb neurons
    • doi: 10.1371/journal.pone.0038174
    • Pathania, M., Torres-Reveron, J., Yan, L., Kimura, T., Lin, T. V., Gordon, V., et al. (2012). miR-132 enhances dendritic morphogenesis, spine density, synaptic integration, and survival of newborn olfactory bulb neurons. PLoS ONE 7:e38174. doi: 10.1371/journal.pone.0038174
    • (2012) PLoS ONE , vol.7
    • Pathania, M.1    Torres-Reveron, J.2    Yan, L.3    Kimura, T.4    Lin, T.V.5    Gordon, V.6
  • 96
    • 84878236414 scopus 로고    scopus 로고
    • Expression Patterns of miR-124, miR-134, miR-132, and miR-21 in an immature rat model and children with mesial temporal lobe epilepsy
    • doi: 10.1007/s12031-013-9953-3
    • Peng, J., Omran, A., Ashhab, M. U., Kong, H., Gan, N., He, F., et al. (2013). Expression Patterns of miR-124, miR-134, miR-132, and miR-21 in an immature rat model and children with mesial temporal lobe epilepsy. J. Mol. Neurosci. 50, 291-297. doi: 10.1007/s12031-013-9953-3
    • (2013) J. Mol. Neurosci , vol.50 , pp. 291-297
    • Peng, J.1    Omran, A.2    Ashhab, M.U.3    Kong, H.4    Gan, N.5    He, F.6
  • 97
    • 84855986489 scopus 로고    scopus 로고
    • Expression profiling of synaptic microRNAs from the adult rat brain identifies regional differences and seizure-induced dynamic modulation
    • doi: 10.1016/j.brainres.2011.12.001
    • Pichardo-Casas, I., Goff, L. A., Swerdel, M. R., Athie, A., Davila, J., Ramos-Brossier, M., et al. (2012). Expression profiling of synaptic microRNAs from the adult rat brain identifies regional differences and seizure-induced dynamic modulation. Brain Res. 1436, 20-33. doi: 10.1016/j.brainres.2011.12.001
    • (2012) Brain Res , vol.1436 , pp. 20-33
    • Pichardo-Casas, I.1    Goff, L.A.2    Swerdel, M.R.3    Athie, A.4    Davila, J.5    Ramos-Brossier, M.6
  • 98
    • 78751488401 scopus 로고    scopus 로고
    • Mechanisms of epileptogenesis and potential treatment targets
    • doi: 10.1016/S14744422(10)70310-0
    • Pitkanen, A., and Lukasiuk, K. (2011a). Mechanisms of epileptogenesis and potential treatment targets. Lancet Neurol. 10, 173-186. doi: 10.1016/S14744422(10)70310-0
    • (2011) Lancet Neurol , vol.10 , pp. 173-186
    • Pitkanen, A.1    Lukasiuk, K.2
  • 99
    • 80054806792 scopus 로고    scopus 로고
    • Molecular biomarkers of epileptogenesis
    • doi: 10.2217/bmm.11.67
    • Pitkanen, A., and Lukasiuk, K. (2011b). Molecular biomarkers of epileptogenesis. Biomark. Med. 5, 629-633. doi: 10.2217/bmm.11.67
    • (2011) Biomark. Med , vol.5 , pp. 629-633
    • Pitkanen, A.1    Lukasiuk, K.2
  • 100
    • 34249822779 scopus 로고    scopus 로고
    • Transcriptional activation of miR-34a contributes to p53-mediated apoptosis
    • doi: 10.1016/j.molcel.2007.05.017
    • Raver-Shapira, N., Marciano, E., Meiri, E., Spector, Y., Rosenfeld, N., Moskovits, N., et al. (2007). Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Mol. Cell. 26, 731-743. doi: 10.1016/j.molcel.2007.05.017
    • (2007) Mol. Cell , vol.26 , pp. 731-743
    • Raver-Shapira, N.1    Marciano, E.2    Meiri, E.3    Spector, Y.4    Rosenfeld, N.5    Moskovits, N.6
  • 101
    • 84872160034 scopus 로고    scopus 로고
    • Changes in microRNA expression in the whole hippocampus and hippocampal synaptoneurosome fraction following pilocarpine induced status epilepticus
    • doi: 10.1371/journal.pone.0053464
    • Risbud, R. M., and Porter, B. E. (2013). Changes in microRNA expression in the whole hippocampus and hippocampal synaptoneurosome fraction following pilocarpine induced status epilepticus. PLoS ONE 8:e53464. doi: 10.1371/journal.pone.0053464
    • (2013) PLoS ONE , vol.8
    • Risbud, R.M.1    Porter, B.E.2
  • 102
    • 84864878892 scopus 로고    scopus 로고
    • Dendritic spines: From structure to in vivo function
    • doi: 10.1038/embor.2012.102
    • Rochefort, N. L., and Konnerth, A. (2012). Dendritic spines: from structure to in vivo function. EMBO Rep. 13, 699-708. doi: 10.1038/embor.2012.102
    • (2012) EMBO Rep , vol.13 , pp. 699-708
    • Rochefort, N.L.1    Konnerth, A.2
  • 103
    • 78650965343 scopus 로고    scopus 로고
    • MicroRNA-134 plasma levels before and after treatment for bipolar mania
    • doi: 10.1016/j.jpsychires.2010.04.028
    • Rong, H., Liu, T. B., Yang, K. J., Yang, H. C., Wu, D. H., Liao, C. P., et al. (2011). MicroRNA-134 plasma levels before and after treatment for bipolar mania. J. Psychiatr. Res. 45, 92-95. doi: 10.1016/j.jpsychires.2010.04.028
    • (2011) J. Psychiatr. Res , vol.45 , pp. 92-95
    • Rong, H.1    Liu, T.B.2    Yang, K.J.3    Yang, H.C.4    Wu, D.H.5    Liao, C.P.6
  • 104
    • 80052982365 scopus 로고    scopus 로고
    • Management of refractory status epilepticus in adults: Still more questions than answers
    • doi: 10.1016/S1474-4422(11)70187-9
    • Rossetti, A. O., and Lowenstein, D. H. (2011). Management of refractory status epilepticus in adults: still more questions than answers. Lancet Neurol. 10, 922-930. doi: 10.1016/S1474-4422(11)70187-9
    • (2011) Lancet Neurol , vol.10 , pp. 922-930
    • Rossetti, A.O.1    Lowenstein, D.H.2
  • 106
    • 34547922786 scopus 로고    scopus 로고
    • Competing interactions between micro-RNAs determine neural progenitor survival and proliferation after ethanol exposure: Evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium
    • doi: 10.1523/JNEUROSCI.1269-07.2007
    • Sathyan, P., Golden, H. B., and Miranda, R. C. (2007). Competing interactions between micro-RNAs determine neural progenitor survival and proliferation after ethanol exposure: evidence from an ex vivo model of the fetal cerebral cortical neuroepithelium. J. Neurosci. 27, 8546-8557. doi: 10.1523/JNEUROSCI.1269-07.2007
    • (2007) J. Neurosci , vol.27 , pp. 8546-8557
    • Sathyan, P.1    Golden, H.B.2    Miranda, R.C.3
  • 107
    • 77956263239 scopus 로고    scopus 로고
    • MicroRNAs as effectors of brain function with roles in ischemia and injury, neuroprotection, and neurodegeneration
    • doi: 10.1038/jcbfm.2010.101
    • Saugstad, J. A. (2010). MicroRNAs as effectors of brain function with roles in ischemia and injury, neuroprotection, and neurodegeneration. J. Cereb. Blood Flow Metab. 30, 1564-1576. doi: 10.1038/jcbfm.2010.101
    • (2010) J. Cereb. Blood Flow Metab , vol.30 , pp. 1564-1576
    • Saugstad, J.A.1
  • 108
    • 78549278078 scopus 로고    scopus 로고
    • Serum microRNAs as a novel class of biomarkers: A comprehensive review of the literature
    • doi: 10.1016/j.exphem.2010.10.004
    • Scholer, N., Langer, C., Dohner, H., Buske, C., and Kuchenbauer, F. (2010). Serum microRNAs as a novel class of biomarkers: a comprehensive review of the literature. Exp. Hematol. 38, 1126-1130. doi: 10.1016/j.exphem.2010.10.004
    • (2010) Exp. Hematol , vol.38 , pp. 1126-1130
    • Scholer, N.1    Langer, C.2    Dohner, H.3    Buske, C.4    Kuchenbauer, F.5
  • 109
    • 70450248489 scopus 로고    scopus 로고
    • microRNAs at the synapse
    • doi: 10.1038/nrn2763
    • Schratt, G. (2009). microRNAs at the synapse. Nat. Rev. Neurosci. 10, 842-849. doi: 10.1038/nrn2763
    • (2009) Nat. Rev. Neurosci , vol.10 , pp. 842-849
    • Schratt, G.1
  • 110
    • 31144479591 scopus 로고    scopus 로고
    • A brain-specific microRNA regulates dendritic spine development
    • doi: 10.1038/nature04367
    • Schratt, G. M., Tuebing, F., Nigh, E. A., Kane, C. G., Sabatini, M. E., Kiebler, M., et al. (2006). A brain-specific microRNA regulates dendritic spine development. Nature 439, 283-289. doi: 10.1038/nature04367
    • (2006) Nature , vol.439 , pp. 283-289
    • Schratt, G.M.1    Tuebing, F.2    Nigh, E.A.3    Kane, C.G.4    Sabatini, M.E.5    Kiebler, M.6
  • 111
    • 4644253753 scopus 로고    scopus 로고
    • A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain
    • doi: 10.1101/gr.2743304
    • Seitz, H., Royo, H., Bortolin, M. L., Lin, S. P., Ferguson-Smith, A. C., and Cavaille, J. (2004). A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain. Genome Res. 14, 1741-1748. doi: 10.1101/gr.2743304
    • (2004) Genome Res , vol.14 , pp. 1741-1748
    • Seitz, H.1    Royo, H.2    Bortolin, M.L.3    Lin, S.P.4    Ferguson-Smith, A.C.5    Cavaille, J.6
  • 112
    • 49949117302 scopus 로고    scopus 로고
    • Widespread changes in protein synthesis induced by microRNAs
    • doi: 10.1038/nature07228
    • Selbach, M., Schwanhausser, B., Thierfelder, N., Fang, Z., Khanin, R., and Rajewsky, N. (2008). Widespread changes in protein synthesis induced by microRNAs. Nature 455, 58-63. doi: 10.1038/nature07228
    • (2008) Nature , vol.455 , pp. 58-63
    • Selbach, M.1    Schwanhausser, B.2    Thierfelder, N.3    Fang, Z.4    Khanin, R.5    Rajewsky, N.6
  • 113
    • 1942494040 scopus 로고    scopus 로고
    • Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
    • doi: 10.1186/gb-2004-5-3-r13
    • Sempere, L. F., Freemantle, S., Pitha-Rowe, I., Moss, E., Dmitrovsky, E., and Ambros, V. (2004). Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol. 5, R13. doi: 10.1186/gb-2004-5-3-r13
    • (2004) Genome Biol , vol.5
    • Sempere, L.F.1    Freemantle, S.2    Pitha-Rowe, I.3    Moss, E.4    Dmitrovsky, E.5    Ambros, V.6
  • 114
    • 0037130455 scopus 로고    scopus 로고
    • Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3
    • doi: 10.1016/S0896-6273(02)00768-7
    • Shahbazian, M., Young, J., Yuva-Paylor, L., Spencer, C., Antalffy, B., Noebels, J., et al. (2002). Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3. Neuron 35, 243-254. doi: 10.1016/S0896-6273(02)00768-7
    • (2002) Neuron , vol.35 , pp. 243-254
    • Shahbazian, M.1    Young, J.2    Yuva-Paylor, L.3    Spencer, C.4    Antalffy, B.5    Noebels, J.6
  • 115
    • 71749084011 scopus 로고    scopus 로고
    • MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase
    • doi: 10.1016/j.immuni.2009.09.019
    • Shaked, I., Meerson, A., Wolf, Y., Avni, R., Greenberg, D., Gilboa-Geffen, A., et al. (2009). MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase. Immunity 31, 965-973. doi: 10.1016/j.immuni.2009.09.019
    • (2009) Immunity , vol.31 , pp. 965-973
    • Shaked, I.1    Meerson, A.2    Wolf, Y.3    Avni, R.4    Greenberg, D.5    Gilboa-Geffen, A.6
  • 116
    • 84872293448 scopus 로고    scopus 로고
    • Hippocampal microRNA-132 mediates stress-inducible cognitive deficits through its acetylcholinesterase target
    • doi: 10.1007/s00429-011-0376-z
    • Shaltiel, G., Hanan, M., Wolf, Y., Barbash, S., Kovalev, E., Shoham, S., et al. (2013). Hippocampal microRNA-132 mediates stress-inducible cognitive deficits through its acetylcholinesterase target. Brain Struct. Funct. 218, 59-72. doi: 10.1007/s00429-011-0376-z
    • (2013) Brain Struct. Funct , vol.218 , pp. 59-72
    • Shaltiel, G.1    Hanan, M.2    Wolf, Y.3    Barbash, S.4    Kovalev, E.5    Shoham, S.6
  • 117
    • 49449096792 scopus 로고    scopus 로고
    • A small molecule enhances RNA interference and promotes microRNA processing
    • doi: 10.1038/nbt.1481
    • Shan, G., Li, Y., Zhang, J., Li, W., Szulwach, K. E., Duan, R., et al. (2008). A small molecule enhances RNA interference and promotes microRNA processing. Nat. Biotechnol. 26, 933-940. doi: 10.1038/nbt.1481
    • (2008) Nat. Biotechnol , vol.26 , pp. 933-940
    • Shan, G.1    Li, Y.2    Zhang, J.3    Li, W.4    Szulwach, K.E.5    Duan, R.6
  • 118
    • 77954067476 scopus 로고    scopus 로고
    • Comprehensive survey of human brain microRNA by deep sequencing
    • doi: 10.1186/1471-2164-11-409
    • Shao, N. Y., Hu, H. Y., Yan, Z., Xu, Y., Hu, H., Menzel, C., et al. (2010). Comprehensive survey of human brain microRNA by deep sequencing. BMC Genomics 11:409. doi: 10.1186/1471-2164-11-409
    • (2010) BMC Genomics , vol.11 , pp. 409
    • Shao, N.Y.1    Hu, H.Y.2    Yan, Z.3    Xu, Y.4    Hu, H.5    Menzel, C.6
  • 119
    • 53049107572 scopus 로고    scopus 로고
    • hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells
    • doi: 10.1016/j.brainres.2008.07.085
    • Shi, L., Cheng, Z., Zhang, J., Li, R., Zhao, P., Fu, Z., et al. (2008). hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells. Brain Res. 1236, 185-193. doi: 10.1016/j.brainres.2008.07.085
    • (2008) Brain Res , pp. 185-193
    • Shi, L.1    Cheng, Z.2    Zhang, J.3    Li, R.4    Zhao, P.5    Fu, Z.6
  • 120
    • 80053597247 scopus 로고    scopus 로고
    • Super-refractory status epilepticus: An approach to therapy in this difficult clinical situation
    • doi: 10.1111/j.15281167.2011.03238.x
    • Shorvon, S. (2011). Super-refractory status epilepticus: an approach to therapy in this difficult clinical situation. Epilepsia 52(Suppl. 8), 53-56. doi: 10.1111/j.15281167.2011.03238.x
    • (2011) Epilepsia , vol.52 , Issue.8 SUPPL. , pp. 53-56
    • Shorvon, S.1
  • 121
    • 66949168048 scopus 로고    scopus 로고
    • A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis
    • doi: 10.1038/ncb1876
    • Siegel, G., Obernosterer, G., Fiore, R., Oehmen, M., Bicker, S., Christensen, M., et al. (2009). A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. Nat. Cell Biol. 11, 705-716. doi: 10.1038/ncb1876
    • (2009) Nat. Cell Biol , vol.11 , pp. 705-716
    • Siegel, G.1    Obernosterer, G.2    Fiore, R.3    Oehmen, M.4    Bicker, S.5    Christensen, M.6
  • 122
    • 84857132739 scopus 로고    scopus 로고
    • Intramuscular versus intravenous therapy for prehospital status epilepticus
    • doi: 10.1056/NEJMoa1107494
    • Silbergleit, R., Durkalski, V., Lowenstein, D., Conwit, R., Pancioli, A., Palesch, Y., et al. (2012). Intramuscular versus intravenous therapy for prehospital status epilepticus. N. Engl. J. Med. 366, 591-600. doi: 10.1056/NEJMoa1107494
    • (2012) N. Engl. J. Med , vol.366 , pp. 591-600
    • Silbergleit, R.1    Durkalski, V.2    Lowenstein, D.3    Conwit, R.4    Pancioli, A.5    Palesch, Y.6
  • 123
    • 84869088933 scopus 로고    scopus 로고
    • Finding a better drug for epilepsy: Preclinical screening strategies and experimental trial design
    • doi: 10.1111/j.1528-1167.2012.03541.x
    • Simonato, M., Loscher, W., Cole, A. J., Dudek, F. E., Engel, J. Jr., Kaminski, R. M., et al. (2012). Finding a better drug for epilepsy: preclinical screening strategies and experimental trial design. Epilepsia 53, 1860-1867. doi: 10.1111/j.1528-1167.2012.03541.x
    • (2012) Epilepsia , vol.53 , pp. 1860-1867
    • Simonato, M.1    Loscher, W.2    Cole, A.J.3    Dudek, F.E.4    Engel Jr., J.5    Kaminski, R.M.6
  • 124
    • 84858782897 scopus 로고    scopus 로고
    • Inhibition of microRNA function by antimiR oligonucleotides
    • doi: 10.1186/1758907X-3-1
    • Stenvang, J., Petri, A., Lindow, M., Obad, S., and Kauppinen, S. (2012). Inhibition of microRNA function by antimiR oligonucleotides. Silence 3, 1. doi: 10.1186/1758907X-3-1
    • (2012) Silence , vol.3 , pp. 1
    • Stenvang, J.1    Petri, A.2    Lindow, M.3    Obad, S.4    Kauppinen, S.5
  • 125
    • 84878437092 scopus 로고    scopus 로고
    • Ketamine use in the treatment of refractory status epilepticus
    • doi: 10.1016/j.eplepsyres.2013. 01.007
    • Synowiec, A. S., Singh, D. S., Yenugadhati, V., Valeriano, J. P., Schramke, C. J., and Kelly, K. M. (2013). Ketamine use in the treatment of refractory status epilepticus. Epilepsy Res. 105, 183-188. doi: 10.1016/j.eplepsyres.2013. 01.007
    • (2013) Epilepsy Res , vol.105 , pp. 183-188
    • Synowiec, A.S.1    Singh, D.S.2    Yenugadhati, V.3    Valeriano, J.P.4    Schramke, C.J.5    Kelly, K.M.6
  • 126
    • 0041593430 scopus 로고    scopus 로고
    • The etiology and diagnosis of status epilepticus
    • doi: 10.1006/ebeh.2001.0195
    • Tatum Iv, W. O., French, J. A., Benbadis, S. R., and Kaplan, P. W. (2001). The etiology and diagnosis of status epilepticus. Epilepsy Behav. 2, 311-317. doi: 10.1006/ebeh.2001.0195
    • (2001) Epilepsy Behav , vol.2 , pp. 311-317
    • Tatum, I.W.O.1    French, J.A.2    Benbadis, S.R.3    Kaplan, P.W.4
  • 127
    • 84876032850 scopus 로고    scopus 로고
    • Protective neuronal induction of ATF5 in endoplasmic reticulum stress induced by status epilepticus
    • doi: 10.1093/brain/awt044
    • Torres-Peraza, J. F., Engel, T., Martin-Ibanez, R., Sanz-Rodriguez, A., Fernandez-Fernandez, M. R., Esgleas, M., et al. (2013). Protective neuronal induction of ATF5 in endoplasmic reticulum stress induced by status epilepticus. Brain 136, 1161-1176. doi: 10.1093/brain/awt044
    • (2013) Brain , vol.136 , pp. 1161-1176
    • Torres-Peraza, J.F.1    Engel, T.2    Martin-Ibanez, R.3    Sanz-Rodriguez, A.4    Fernandez-Fernandez, M.R.5    Esgleas, M.6
  • 128
    • 80052381608 scopus 로고    scopus 로고
    • Characterization of extracellular circulating microRNA
    • doi: 10.1093/nar/gkr254
    • Turchinovich, A., Weiz, L., Langheinz, A., and Burwinkel, B. (2011). Characterization of extracellular circulating microRNA. Nucleic Acids Res. 39, 7223-7233. doi: 10.1093/nar/gkr254
    • (2011) Nucleic Acids Res , vol.39 , pp. 7223-7233
    • Turchinovich, A.1    Weiz, L.2    Langheinz, A.3    Burwinkel, B.4
  • 129
    • 78651369895 scopus 로고    scopus 로고
    • The role of inflammation in epilepsy
    • doi: 10.1038/nrneurol.2010.178
    • Vezzani, A., French, J., Bartfai, T., and Baram, T. Z. (2011). The role of inflammation in epilepsy. Nat. Rev. Neurol. 7, 31-40. doi: 10.1038/nrneurol.2010.178
    • (2011) Nat. Rev. Neurol , vol.7 , pp. 31-40
    • Vezzani, A.1    French, J.2    Bartfai, T.3    Baram, T.Z.4
  • 130
    • 28044439909 scopus 로고    scopus 로고
    • A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis
    • doi: 10.1073/pnas.0508448102
    • Vo, N., Klein, M. E., Varlamova, O., Keller, D. M., Yamamoto, T., Goodman, R. H., et al. (2005). A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc. Natl. Acad. Sci. U.S.A. 102, 16426-16431. doi: 10.1073/pnas.0508448102
    • (2005) Proc. Natl. Acad. Sci. U.S.A , vol.102 , pp. 16426-16431
    • Vo, N.1    Klein, M.E.2    Varlamova, O.3    Keller, D.M.4    Yamamoto, T.5    Goodman, R.H.6
  • 131
    • 0034625010 scopus 로고    scopus 로고
    • Potent and nontoxic antisense oligonucleotides containing locked nucleic acids
    • doi: 10.1073/pnas.97.10.5633
    • Wahlestedt, C., Salmi, P., Good, L., Kela, J., Johnsson, T., Hokfelt, T., et al. (2000). Potent and nontoxic antisense oligonucleotides containing locked nucleic acids. Proc. Natl. Acad. Sci. U.S.A. 97, 5633-5638. doi: 10.1073/pnas.97.10.5633
    • (2000) Proc. Natl. Acad. Sci. U.S.A , vol.97 , pp. 5633-5638
    • Wahlestedt, C.1    Salmi, P.2    Good, L.3    Kela, J.4    Johnsson, T.5    Hokfelt, T.6
  • 132
    • 71549115197 scopus 로고    scopus 로고
    • Global expression profiling in epileptogenesis: Does it add to the confusion?
    • doi: 10.1111/j.1750-3639.2008.00254.x
    • Wang, Y. Y., Smith, P., Murphy, M., and Cook, M. (2010). Global expression profiling in epileptogenesis: does it add to the confusion? Brain Pathol. 20, 1-16. doi: 10.1111/j.1750-3639.2008.00254.x
    • (2010) Brain Pathol , vol.20 , pp. 1-16
    • Wang, Y.Y.1    Smith, P.2    Murphy, M.3    Cook, M.4
  • 133
    • 79952282998 scopus 로고    scopus 로고
    • Let-7/miR98 regulate Fas and Fas-mediated apoptosis
    • doi: 10.1038/gene.2010.53
    • Wang, S., Tang, Y., Cui, H., Zhao, X., Luo, X., Pan, W., et al. (2011). Let-7/miR98 regulate Fas and Fas-mediated apoptosis. Genes Immun. 12, 149-154. doi: 10.1038/gene.2010.53
    • (2011) Genes Immun , vol.12 , pp. 149-154
    • Wang, S.1    Tang, Y.2    Cui, H.3    Zhao, X.4    Luo, X.5    Pan, W.6
  • 134
    • 79961075823 scopus 로고    scopus 로고
    • Molecular basis of self-sustaining seizures and pharmacoresistance during status epilepticus: The receptor trafficking hypothesis revisited
    • doi: 10.1111/j.1528-1167.2009.02375.x
    • Wasterlain, C. G., Liu, H., Naylor, D. E., Thompson, K. W., Suchomelova, L., Niquet, J., et al. (2009). Molecular basis of self-sustaining seizures and pharmacoresistance during status epilepticus: the receptor trafficking hypothesis revisited. Epilepsia 50(Suppl. 12), 16-18. doi: 10.1111/j.1528-1167.2009.02375.x
    • (2009) Epilepsia , vol.50 , Issue.12 SUPPL. , pp. 16-18
    • Wasterlain, C.G.1    Liu, H.2    Naylor, D.E.3    Thompson, K.W.4    Suchomelova, L.5    Niquet, J.6
  • 135
    • 48249095979 scopus 로고    scopus 로고
    • An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP
    • doi: 10.1073/pnas.0803072105
    • Wayman, G. A., Davare, M., Ando, H., Fortin, D., Varlamova, O., Cheng, H. Y., et al. (2008). An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP. Proc. Natl. Acad. Sci. U.S.A. 105, 9093-9098. doi: 10.1073/pnas.0803072105
    • (2008) Proc. Natl. Acad. Sci. U.S.A , vol.105 , pp. 9093-9098
    • Wayman, G.A.1    Davare, M.2    Ando, H.3    Fortin, D.4    Varlamova, O.5    Cheng, H.Y.6
  • 136
    • 80054818124 scopus 로고    scopus 로고
    • miR-497 and miR-302b regulate ethanol-induced neuronal cell death through BCL2 protein and cyclin D2
    • doi: 10.1074/jbc.M111.235531
    • Yadav, S., Pandey, A., Shukla, A., Talwelkar, S. S., Kumar, A., Pant, A. B., et al. (2011). miR-497 and miR-302b regulate ethanol-induced neuronal cell death through BCL2 protein and cyclin D2. J. Biol. Chem. 286, 37347-37357. doi: 10.1074/jbc.M111.235531
    • (2011) J. Biol. Chem , vol.286 , pp. 37347-37357
    • Yadav, S.1    Pandey, A.2    Shukla, A.3    Talwelkar, S.S.4    Kumar, A.5    Pant, A.B.6
  • 137
    • 77549088509 scopus 로고    scopus 로고
    • miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia
    • doi: 10.1016/j.nbd.2009.12.021
    • Yin, K. J., Deng, Z., Huang, H., Hamblin, M., Xie, C., Zhang, J., et al. (2010). miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia. Neurobiol. Dis. 38, 17-26. doi: 10.1016/j.nbd.2009.12.021
    • (2010) Neurobiol. Dis , vol.38 , pp. 17-26
    • Yin, K.J.1    Deng, Z.2    Huang, H.3    Hamblin, M.4    Xie, C.5    Zhang, J.6
  • 138
    • 81955164885 scopus 로고    scopus 로고
    • Decreased CREB levels suppress epilepsy
    • doi: 10.1016/j.nbd.2011.08.009
    • Zhu, X., Han, X., Blendy, J. A., and Porter, B. E. (2012). Decreased CREB levels suppress epilepsy. Neurobiol. Dis. 45, 253-263. doi: 10.1016/j.nbd.2011.08.009
    • (2012) Neurobiol. Dis , vol.45 , pp. 253-263
    • Zhu, X.1    Han, X.2    Blendy, J.A.3    Porter, B.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.