-
1
-
-
0030867774
-
The ubiquitin system
-
Varshavsky, A. The ubiquitin system. Trends Biochem. Sci. 22, 383-387 (1997).
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 383-387
-
-
Varshavsky, A.1
-
2
-
-
0031603760
-
A function for monoubiquitination in the internalization of a G protein-coupled receptor
-
Terrell, J., Shih, S., Dunn, R. & Hicke, L. A function for monoubiquitination in the internalization of a G protein-coupled receptor. Mol. Cell 1, 193-202 (1998).
-
(1998)
Mol. Cell
, vol.1
, pp. 193-202
-
-
Terrell, J.1
Shih, S.2
Dunn, R.3
Hicke, L.4
-
3
-
-
0034616943
-
Cell cycle-regulated modification of the ribosome by a variant maltiubiquitin chain
-
Spence, J. et al. Cell cycle-regulated modification of the ribosome by a variant maltiubiquitin chain. Cell 102, 67-76 (2000).
-
(2000)
Cell
, vol.102
, pp. 67-76
-
-
Spence, J.1
-
4
-
-
0010586475
-
The 19S regulatory complex of the proteasome functions independently of proteolysis in nucleotide excision repair
-
Russell, S. J., Reed, S. H., Huang, W., Friedberg, E. C. & Johnston, S. A. The 19S regulatory complex of the proteasome functions independently of proteolysis in nucleotide excision repair. Mol. Cell 3, 687-695 (1999).
-
(1999)
Mol. Cell
, vol.3
, pp. 687-695
-
-
Russell, S.J.1
Reed, S.H.2
Huang, W.3
Friedberg, E.C.4
Johnston, S.A.5
-
5
-
-
0016751733
-
Isolation and characterization of protein A24, a 'histone-like' non-histone chromosomal protein
-
Goldknopf, I. L. et al. Isolation and characterization of protein A24, a 'histone-like' non-histone chromosomal protein. J. Biol. Chem. 250, 7182-7187 (1975).
-
(1975)
J. Biol. Chem.
, vol.250
, pp. 7182-7187
-
-
Goldknopf, I.L.1
-
6
-
-
0017601447
-
Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24
-
Goldknopf, I. L. & Busch, H. Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24. Proc. Natl Acad. Sci. USA 74, 864-868 (1977).
-
(1977)
Proc. Natl. Acad. Sci. USA
, vol.74
, pp. 864-868
-
-
Goldknopf, I.L.1
Busch, H.2
-
7
-
-
0017327721
-
Terminal sequence identity of ubiquitin and the nonhistone component of nuclear protein A24
-
Hunt, L. T. & Dayhoff, M. O. terminal sequence identity of ubiquitin and the nonhistone component of nuclear protein A24. Biochem. Biophys. Res. Commun. 74, 650-655 (1977).
-
(1977)
Biochem. Biophys. Res. Commun.
, vol.74
, pp. 650-655
-
-
Hunt, L.T.1
Dayhoff, M.O.2
-
8
-
-
0020055316
-
Selective arrangement of ubiquitinated and D1 protein-containing nucleosomes within the Drosophila genome
-
Levinger, L. & Varshavsky, A. Selective arrangement of ubiquitinated and D1 protein-containing nucleosomes within the Drosophila genome. Cell 28, 375-385 (1982).
-
(1982)
Cell
, vol.28
, pp. 375-385
-
-
Levinger, L.1
Varshavsky, A.2
-
9
-
-
0024505572
-
Ubiquitinated histone H2B is preferentially located in transcriptionally active chromatin
-
Nickel, B. E., Allis, C. D. & Davie, J. R. Ubiquitinated histone H2B is preferentially located in transcriptionally active chromatin. Biochemistry 28, 958-963 (1989).
-
(1989)
Biochemistry
, vol.28
, pp. 958-963
-
-
Nickel, B.E.1
Allis, C.D.2
Davie, J.R.3
-
10
-
-
0025341218
-
Level of ubiquitinated histone H2B in chromatin is coupled to ongoing transcription
-
Davie, J. R. & Murphy, L. C. Level of ubiquitinated histone H2B in chromatin is coupled to ongoing transcription. Biochemistry 29, 4752-4757 (1990).
-
(1990)
Biochemistry
, vol.29
, pp. 4752-4757
-
-
Davie, J.R.1
Murphy, L.C.2
-
11
-
-
0026024562
-
Timing of the appearance of ubiquitinated histones in developing new macronuclei of Tetrahymena thermophila
-
Davie, J. R., Lin, R. & Allis, C. D. Timing of the appearance of ubiquitinated histones in developing new macronuclei of Tetrahymena thermophila. Biochem. Cell Biol. 69, 66-71 (1991).
-
(1991)
Biochem. Cell Biol.
, vol.69
, pp. 66-71
-
-
Davie, J.R.1
Lin, R.2
Allis, C.D.3
-
12
-
-
0020478758
-
Regulation of histone acetylation in Tetrahymena macro- and micronuclei
-
Vavra, K. J., Allis, C. D. & Gorovsky, M. A. Regulation of histone acetylation in Tetrahymena macro- and micronuclei. J. Biol. Chem. 257, 2591-2598 (1982).
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 2591-2598
-
-
Vavra, K.J.1
Allis, C.D.2
Gorovsky, M.A.3
-
13
-
-
0022444464
-
The active immunoglobulin κ chain gene is packaged by non-ubiquitin-conjugated nucleosomes
-
Huang, S. Y. et al. The active immunoglobulin κ chain gene is packaged by non-ubiquitin-conjugated nucleosomes. Proc. Natl Acad. Sci. USA 83, 3738-3742 (1986).
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 3738-3742
-
-
Huang, S.Y.1
-
14
-
-
0034730745
-
Ubiquitin-activating/conjugating activity of TAFII 250, a mediator of activation of gene expression in Drosophila
-
Pham, A. D. & Sauer, F. Ubiquitin-activating/conjugating activity of TAFII250, a mediator of activation of gene expression in Drosophila. Science 289, 2357-2360 (2000).
-
(2000)
Science
, vol.289
, pp. 2357-2360
-
-
Pham, A.D.1
Sauer, F.2
-
15
-
-
0010115729
-
Ubiquitination of histone H3 in elongating spermatids of rat testes
-
Chen, H. Y., Sun, J. M., Zhang, Y., Davie, J. R. & Meistrich, M. L. Ubiquitination of histone H3 in elongating spermatids of rat testes. J. Biol. Chem. 273, 13165-13169 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13165-13169
-
-
Chen, H.Y.1
Sun, J.M.2
Zhang, Y.3
Davie, J.R.4
Meistrich, M.L.5
-
16
-
-
0034695456
-
A Rad6-dependent ubiquitination of histone H2B in yeast
-
Robzyk, K., Recht, J. & Osley, M. A Rad6-dependent ubiquitination of histone H2B in yeast. Science 287, 501-504 (2000). Identified Rad6 as a Ub-conjugating enzyme for histone H2B in budding yeast and opened the way for genetic analysis of histone ubiquitylation.
-
(2000)
Science
, vol.287
, pp. 501-504
-
-
Robzyk, K.1
Recht, J.2
Osley, M.3
-
17
-
-
0036265403
-
The E2 ubiquitin conjugase Rad6 is required for the ArgR/Mcm1 repression of ARG1 transcription
-
Turner, S. D. et al. The E2 ubiquitin conjugase Rad6 is required for the ArgR/Mcm1 repression of ARG1 transcription. Mol. Cell. Biol. 22, 4011-4019 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4011-4019
-
-
Turner, S.D.1
-
18
-
-
0032814843
-
A general requirement for the Sin3-Rpd3 histone deacetylase complex in regulating silencing in Saccharomyces cerevisiae
-
Sun, Z. W. & Hampsey, M. A general requirement for the Sin3-Rpd3 histone deacetylase complex in regulating silencing in Saccharomyces cerevisiae. Genetics 152, 921-932 (1999).
-
(1999)
Genetics
, vol.152
, pp. 921-932
-
-
Sun, Z.W.1
Hampsey, M.2
-
19
-
-
0030758377
-
The ubiquitin-conjugating enzyme Rad6 (Ubc2) is required for silencing in Saccharomyces cerevisiae
-
Huang, H., Kahana, A., Gottschling, D. E., Prakash, L. & Liebman, S. W. The ubiquitin-conjugating enzyme Rad6 (Ubc2) is required for silencing in Saccharomyces cerevisiae. Mol. Cell. Biol. 17, 6693-6699 (1997).
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 6693-6699
-
-
Huang, H.1
Kahana, A.2
Gottschling, D.E.3
Prakash, L.4
Liebman, S.W.5
-
20
-
-
0031044789
-
Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast
-
Bryk, M. et al. Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast. Genes Dev. 11, 255-269 (1997).
-
(1997)
Genes Dev.
, vol.11
, pp. 255-269
-
-
Bryk, M.1
-
21
-
-
0036258095
-
Components of the SAGA histone acetyltransferase complex are required for repressed transcription of ARG1 in rich medium
-
Ricci, A. R., Genereaux, J. & Brandl, C. J. Components of the SAGA histone acetyltransferase complex are required for repressed transcription of ARG1 in rich medium. Mol. Cell. Biol. 22, 4033-4042 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4033-4042
-
-
Ricci, A.R.1
Genereaux, J.2
Brandl, C.J.3
-
22
-
-
0037019333
-
Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast
-
Sun, Z. W. & Allis, C. D. Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature 418, 104-108 (2002). Established that histone ubiquitylation is required for subsequent histone modifications that are important in gene silencing.
-
(2002)
Nature
, vol.418
, pp. 104-108
-
-
Sun, Z.W.1
Allis, C.D.2
-
23
-
-
0036682364
-
Gene silencing: Trans-histone regulatory pathway in chromatin
-
Briggs, S. D. et al. Gene silencing: Trans-histone regulatory pathway in chromatin. Nature 418, 496 (2002).
-
(2002)
Nature
, vol.418
, pp. 496
-
-
Briggs, S.D.1
-
24
-
-
0035370439
-
Histone methylation versus histone acetylation: New insights into epigenetic regulation
-
Rice, J. C. & Allis, C. D. Histone methylation versus histone acetylation: new insights into epigenetic regulation. Curr. Opin. Cell. Biol. 13, 263-273 (2001).
-
(2001)
Curr. Opin. Cell. Biol.
, vol.13
, pp. 263-273
-
-
Rice, J.C.1
Allis, C.D.2
-
25
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl, B. D. & Allis, C. D. The language of covalent histone modifications. Nature 403, 41-45 (2000).
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
26
-
-
0019877051
-
Rapid turnover of the histone-ubiquitin conjugate, protein A24
-
Seale, R. L. Rapid turnover of the histone-ubiquitin conjugate, protein A24. Nucleic Acids Res. 9, 3151-3158 (1981).
-
(1981)
Nucleic Acids Res.
, vol.9
, pp. 3151-3158
-
-
Seale, R.L.1
-
27
-
-
0019877029
-
Metabolism of ubiquitinated histones
-
Wu, R. S., Kohn, K. W. & Bonner, W. M. Metabolism of ubiquitinated histones. J. Biol. Chem. 256, 5916-5920 (1981).
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 5916-5920
-
-
Wu, R.S.1
Kohn, K.W.2
Bonner, W.M.3
-
28
-
-
0025605089
-
Ubiquitin-mediated degradation of histone H3 does not require the substrate-binding ubiquitin protein ligase, E 3, or attachment of polyubiquitin chains
-
Haas, A., Reback, P. M., Pratt, G. & Rechsteiner M. Ubiquitin-mediated degradation of histone H3 does not require the substrate-binding ubiquitin protein ligase, E3, or attachment of polyubiquitin chains. J. Biol. Chem. 265, 21664-21669 (1990).
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 21664-21669
-
-
Haas, A.1
Reback, P.M.2
Pratt, G.3
Rechsteiner, M.4
-
29
-
-
0037134015
-
Recruitment of a 19S proteasome subcomplex to an activated promoter
-
Gonzalez, F., Delahodde, A., Kodadek, T. & Johnston, S. A. Recruitment of a 19S proteasome subcomplex to an activated promoter Science 296, 548-550 (2002). Showed that components of the 19S proteasome are recruited to a transcriptionally-active gene in yeast.
-
(2002)
Science
, vol.296
, pp. 548-550
-
-
Gonzalez, F.1
Delahodde, A.2
Kodadek, T.3
Johnston, S.A.4
-
30
-
-
0037108963
-
Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes
-
Hook, S. S., Orian, A., Cowley, S. M. & Eisenman, R. N. Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes. Proc. Natl Acad. Sci. USA 99, 13425-13430 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13425-13430
-
-
Hook, S.S.1
Orian, A.2
Cowley, S.M.3
Eisenman, R.N.4
-
31
-
-
0037179716
-
Active genes are tri-methylated at K4 of histone H3
-
Santos-Rosa, H. et al. Active genes are tri-methylated at K4 of histone H3. Nature 419, 407-411 (2002).
-
(2002)
Nature
, vol.419
, pp. 407-411
-
-
Santos-Rosa, H.1
-
32
-
-
0028108925
-
Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators
-
Chen, J. L., Attardi, L. D., Verrijzer, C. P., Yokomon, K. & Tjian, R. Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators. Cell 79, 93-105 (1994).
-
(1994)
Cell
, vol.79
, pp. 93-105
-
-
Chen, J.L.1
Attardi, L.D.2
Verrijzer, C.P.3
Yokomon, K.4
Tjian, R.5
-
33
-
-
0030598895
-
A deubiquitinating enzyme interacts with SIR4 and regulates silencing in S. cerevisiae
-
Moazed, D. & Johnson, D. A deubiquitinating enzyme interacts with SIR4 and regulates silencing in S. cerevisiae. Cell 86, 667-677 (1996).
-
(1996)
Cell
, vol.86
, pp. 667-677
-
-
Moazed, D.1
Johnson, D.2
-
34
-
-
0036318573
-
Molecular characterization of Saccharomyces cerevisiae TFIID
-
Sanders, S. L., Garbett, K. A. & Weil, P. A. Molecular characterization of Saccharomyces cerevisiae TFIID. Mol. Cell. Biol. 22, 6000-6013 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6000-6013
-
-
Sanders, S.L.1
Garbett, K.A.2
Weil, P.A.3
-
35
-
-
0036363646
-
Mechanisms of transcription-coupled DNA repair
-
Svejstrup, J. Q. Mechanisms of transcription-coupled DNA repair. Nature Rev. Mol. Cell. Biol. 3, 21-29 (2002).
-
(2002)
Nature Rev. Mol. Cell. Biol.
, vol.3
, pp. 21-29
-
-
Svejstrup, J.Q.1
-
36
-
-
0037007036
-
Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro
-
Lee, K. B., Wang, D., Lippard, S. J. & Sharp, P. A. Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro Proc. Natl Acad. Sci. USA 99, 4239-4244 (2002) Provided biochemical evidence that DNA-damage-dependent ubiquitylation of RNA polymerase II is coupled to transcription.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 4239-4244
-
-
Lee, K.B.1
Wang, D.2
Lippard, S.J.3
Sharp, P.A.4
-
37
-
-
0032827035
-
Rsp5 ubiquitin-protein ligase mediates DNA damage-induced degradation of the large subunit of RNA polymerase II in Saccharomyces cerevisiae
-
Beaudenon, S. L., Huacani, M. R., Wang, G., McDonnell, D. P. & Huibregtse, J. M. Rsp5 ubiquitin-protein ligase mediates DNA damage-induced degradation of the large subunit of RNA polymerase II in Saccharomyces cerevisiae. Mol. Cell. Biol. 19, 6972-6979 (1999)
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6972-6979
-
-
Beaudenon, S.L.1
Huacani, M.R.2
Wang, G.3
McDonnell, D.P.4
Huibregtse, J.M.5
-
38
-
-
0030888109
-
The large subunit of RNA polymerase II is a substrate of the Rsp5 ubiquitin-protein ligase
-
Huibregtse, J. M., Yang, J. C. & Beaudenon, S. L. The large subunit of RNA polymerase II is a substrate of the Rsp5 ubiquitin-protein ligase. Proc. Natl Acad. Sci. USA 94, 3656-3661 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3656-3661
-
-
Huibregtse, J.M.1
Yang, J.C.2
Beaudenon, S.L.3
-
39
-
-
0034307008
-
Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription
-
Komamitsky, P., Cho, E. J. & Buratowski, S. Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors dunng transcript on. Genes Dev. 14, 2452-2460 (2000).
-
(2000)
Genes Dev.
, vol.14
, pp. 2452-2460
-
-
Komamitsky, P.1
Cho, E.J.2
Buratowski, S.3
-
40
-
-
0032991645
-
Ubiquitination of RNA polymerase II large subunit signaled by phosphorylation of carboxylterminal domain
-
Mitsui, A. & Sharp, P. A. Ubiquitination of RNA polymerase II large subunit signaled by phosphorylation of carboxylterminal domain. Proc. Natl Acad. Sci. USA 96, 6054-6059 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 6054-6059
-
-
Mitsui, A.1
Sharp, P.A.2
-
41
-
-
0029953663
-
Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptors
-
Imhof, M. O. & McDonnell, D. P. Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptors. Mol. Cell. Biol. 16, 2594-2605 (1996).
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2594-2605
-
-
Imhof, M.O.1
McDonnell, D.P.2
-
42
-
-
0037148786
-
A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage
-
Woudstra, E. C. et al. A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage. Nature 415, 929-933 (2002).
-
(2002)
Nature
, vol.415
, pp. 929-933
-
-
Woudstra, E.C.1
-
43
-
-
0030840464
-
STATs and gene regulation
-
Darnell, J. E., Jr. STATs and gene regulation Science 277, 1630-1635 (1997).
-
(1997)
Science
, vol.277
, pp. 1630-1635
-
-
Darnell J.E., Jr.1
-
44
-
-
0034681260
-
Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans
-
Brown, M. S., Ye, J., Rawson, R. B. & Goldstein, J. L. Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans. Cell 100, 391-398 (2000).
-
(2000)
Cell
, vol.100
, pp. 391-398
-
-
Brown, M.S.1
Ye, J.2
Rawson, R.B.3
Goldstein, J.L.4
-
45
-
-
0027980321
-
The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB
-
Palombella, V. J., Rando, O. J. Goldberg, A. L. & Maniatis, T. The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB. Cell 78, 773-785 (1994).
-
(1994)
Cell
, vol.78
, pp. 773-785
-
-
Palombella, V.J.1
Rando, O.J.2
Goldberg, A.L.3
Maniatis, T.4
-
46
-
-
0034268493
-
Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing
-
Hoppe, T. et al. Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing. Cell 102, 577-586 (2000).
-
(2000)
Cell
, vol.102
, pp. 577-586
-
-
Hoppe, T.1
-
47
-
-
0035977095
-
Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone
-
Rape, M. et al. Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone. Cell 107, 667-677 (2001).
-
(2001)
Cell
, vol.107
, pp. 667-677
-
-
Rape, M.1
-
48
-
-
0036318221
-
Pondering the promyelocytic leukemia protein (PML) puzzle: Possible functions for PML nL clear bodies
-
Borden, K. L. Pondering the promyelocytic leukemia protein (PML) puzzle: possible functions for PML nL clear bodies. Mol. Cell. Biol. 22, 5259-5269 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 5259-5269
-
-
Borden, K.L.1
-
49
-
-
0037498052
-
Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus
-
Muller, S., Matunis, M. J. & Dejean, A. Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus. EMBO J. 17, 61-70 (1998).
-
(1998)
EMBO J.
, vol.17
, pp. 61-70
-
-
Muller, S.1
Matunis, M.J.2
Dejean, A.3
-
50
-
-
0035576878
-
PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies
-
Sachdev, S. et al. PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies. Genes Dev. 15, 3088-3103 (2001). Established a solid connection between SUMO-modification of a transcription factor, transcriptional regulation and PML-body formation.
-
(2001)
Genes Dev.
, vol.15
, pp. 3088-3103
-
-
Sachdev, S.1
-
51
-
-
0036809115
-
SUHO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization
-
Ross, S., Best, J. L., Zon, L. I. & Gill, G. SUHO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization. Mol. Cell 10, 831-842 (2002).
-
(2002)
Mol. Cell
, vol.10
, pp. 831-842
-
-
Ross, S.1
Best, J.L.2
Zon, L.I.3
Gill, G.4
-
52
-
-
0036792683
-
Transcription factor Sp3 is silenced through SUMO modification by PIAS1
-
Sapetschnig, A. et al. Transcription factor Sp3 is silenced through SUMO modification by PIAS1. EMBO J. 21, 5206-5215 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 5206-5215
-
-
Sapetschnig, A.1
-
53
-
-
0037088588
-
Covalent attachment of the SUMO-1 protein to the negative regulatory domain of the c-Myb transcription factor modifies its stability and transactivation capacity
-
Bies, J., Markus, J. & Wolff, L. Covalent attachment of the SUMO-1 protein to the negative regulatory domain of the c-Myb transcription factor modifies its stability and transactivation capacity. J. Biol. Chem. 277, 8999-9009 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8999-9009
-
-
Bies, J.1
Markus, J.2
Wolff, L.3
-
54
-
-
0036826887
-
PIAS1 and PIASxα function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription
-
Nishida, T. & Yasuda, H. PIAS1 and PIASxα function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription. J. Biol. Chem. 277, 41311-41317 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 41311-41317
-
-
Nishida, T.1
Yasuda, H.2
-
55
-
-
0037022564
-
Members of the PIAS family act as SUMO ligases for c-Jun and p 53 and repress p53 activity
-
Schmidt, D. & Muller, S. Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity. Proc. Natl Acad. Sci. USA 99, 2872-2877 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 2872-2877
-
-
Schmidt, D.1
Muller, S.2
-
56
-
-
0037064083
-
Transcriptional activity of CCAAT/enhancer-binding proteins is controlled by a conserved inhibitory domain that is a target for sumoylation
-
Kim, J., Cantwell, C. A., Johnson, P. F., Pfan, C. M. & Williams, S. C. Transcriptional activity of CCAAT/enhancer-binding proteins is controlled by a conserved inhibitory domain that is a target for sumoylation. J. Biol. Chem. 277, 38037-38044 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38037-38044
-
-
Kim, J.1
Cantwell, C.A.2
Johnson, P.F.3
Pfan, C.M.4
Williams, S.C.5
-
57
-
-
0037034807
-
Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors
-
Ostendorff, H. P. et al. Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors. Nature 416, 99-103 (2002).
-
(2002)
Nature
, vol.416
, pp. 99-103
-
-
Ostendorff, H.P.1
-
58
-
-
0034604341
-
Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Mel30)-mediated inactivation of the transcription factor Met4
-
Kaiser, P., Flick, K., Wittenberg, C. & Reed, S. I. Regulation of transcription by ubiquitination without proteolysis: Cdc34/SCF(Mel30)-mediated inactivation of the transcription factor Met4. Cell 102, 303-314 (2000).
-
(2000)
Cell
, vol.102
, pp. 303-314
-
-
Kaiser, P.1
Flick, K.2
Wittenberg, C.3
Reed, S.I.4
-
60
-
-
0036348150
-
Dual regulation of the met4 transcription factor by ubiquitin-dependent degradation and inhibition of promoter recruitment
-
Kuras, L. et al. Dual regulation of the met4 transcription factor by ubiquitin-dependent degradation and inhibition of promoter recruitment. Mol. Cell 10, 69-80 (2002). Showed that the yeast transcription factor Met4 can be either inactivated or destroyed by Met30-dependent ubiquitylation, depending on nutrients.
-
(2002)
Mol. Cell
, vol.10
, pp. 69-80
-
-
Kuras, L.1
-
61
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis, P. Wnt signaling and cancer. Genes Dev. 14, 1837-1851 (2000).
-
(2000)
Genes Dev.
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
62
-
-
0030978351
-
β-catenin is a target for the ubiquitin-proteasome pathway
-
Aberle, H., Bauer, A., Stappert, J. Kispert, A. & Kemler, R. β-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 16, 3797-3804 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 3797-3804
-
-
Aberle, H.1
Bauer, A.2
Stappert, J.3
Kispert, A.4
Kemler, R.5
-
63
-
-
0029683606
-
The axis-inducing activity, stability, and subcellular distribution of β-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3
-
Yost, C. et al. The axis-inducing activity, stability, and subcellular distribution of β-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3, Genes Dev. 10, 1443-1454 (1996).
-
(1996)
Genes Dev.
, vol.10
, pp. 1443-1454
-
-
Yost, C.1
-
64
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt, Y., Maya, R., Kazaz, A & Oren, M. Mdm2 promotes the rapid degradation of p53. Nature 387, 296-299 (1997).
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
65
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell, P. H. et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399, 271-275 (1999).
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
-
66
-
-
0034708774
-
2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway. Role of the transcription activation and DNA binding of AhR
-
Ma, Q. & Baldwin, K. T. 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway. Role of the transcription activation and DNA binding of AhR. J. Biol. Chem. 275, 8432-8438 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8432-8438
-
-
Ma, Q.1
Baldwin, K.T.2
-
67
-
-
0033257926
-
Ubiquitin-dependent degradation of TGF-β-activated Smad2
-
Lo, R. S. & Massague, J. Ubiquitin-dependent degradation of TGF-β-activated Smad2. Nature Cell. Biol. 1, 472-478 (1999).
-
(1999)
Nature Cell. Biol.
, vol.1
, pp. 472-478
-
-
Lo, R.S.1
Massague, J.2
-
68
-
-
0000413462
-
Regulation of interferon-γ-activated STAT1 by the ubiquitin-proteasome pathway
-
Kim, T. K. & Maniatis, T. Regulation of interferon-γ-activated STAT1 by the ubiquitin-proteasome pathway. Science 273, 1717-1719 (1996).
-
(1996)
Science
, vol.273
, pp. 1717-1719
-
-
Kim, T.K.1
Maniatis, T.2
-
69
-
-
0035937480
-
An internal region of the RpoH heat shock transcription factor is critical for rapid degradation by the FtsH protease
-
Bertani, D., Oppenheim, A. B. & Narbemaus, F. An internal region of the RpoH heat shock transcription factor is critical for rapid degradation by the FtsH protease. FEBS Lett. 493, 17-20 (2001).
-
(2001)
FEBS Lett.
, vol.493
, pp. 17-20
-
-
Bertani, D.1
Oppenheim, A.B.2
Narbemaus, F.3
-
70
-
-
0032989449
-
Regulation of RpoS proteolysis in Escherichia coli: The response regulator RssB is a recognition factor that interacts with the turnover element in RpoS
-
Becker, G., Klauck, E. & Hengge-Aronis, R. Regulation of RpoS proteolysis in Escherichia coli: the response regulator RssB is a recognition factor that interacts with the turnover element in RpoS. Proc. Natl Acad. Sci. USA 96, 6439-6444 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 6439-6444
-
-
Becker, G.1
Klauck, E.2
Hengge-Aronis, R.3
-
71
-
-
0033081027
-
Destruction of Myc by ubiquitin-mediated proteolysis: Cancer-associated and transforming mutations stabilize Myc
-
Salghetti, S. E., Kim, S. Y. & Tansey, W. P. Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc. EMBO J. 18, 717-726 (1999).
-
(1999)
EMBO J.
, vol.18
, pp. 717-726
-
-
Salghetti, S.E.1
Kim, S.Y.2
Tansey, W.P.3
-
72
-
-
0034724166
-
Functional overlap of sequences that activate transcription and signal ubiquitin-mediated proteolysis
-
Salghetti, S. E., Muratani, M., Wijnen, H., Futcher, B. & Tansey, W. P. Functional overlap of sequences that activate transcription and signal ubiquitin-mediated proteolysis. Proc. Natl Acad. Sci. USA 97, 3118-3123 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 3118-3123
-
-
Salghetti, S.E.1
Muratani, M.2
Wijnen, H.3
Futcher, B.4
Tansey, W.P.5
-
73
-
-
0033571527
-
Proteasome-mediated degradation of transcriptional activators correlates with activation domain potency in viva
-
Molinari, E., Gilman, M. & Natesan, S. Proteasome-mediated degradation of transcriptional activators correlates with activation domain potency in viva. EMBO J. 18, 6439-6447 (1999).
-
(1999)
EMBO J.
, vol.18
, pp. 6439-6447
-
-
Molinari, E.1
Gilman, M.2
Natesan, S.3
-
74
-
-
0036678409
-
Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase
-
Brower C. S. et al. Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase. Proc. Natl Acad. Sci. USA 99, 10353-10358 (2002). Established that Ub-ligase activity is directly associated with the RNA polymerase II holoenzyme.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 10353-10358
-
-
Brower, C.S.1
-
75
-
-
0035339092
-
Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase
-
Chi, Y. et al. Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase. Genes Dev. 15, 1078-1092 (2001). Showed that the yeast transcription factor GCN4 is marked for destruction by a kinase that is present in the RNA polymerase II holoenzyme.
-
(2001)
Genes Dev.
, vol.15
, pp. 1078-1092
-
-
Chi, Y.1
-
76
-
-
0028937199
-
A kinase-cyclin pair in the RNA polymerase II holoenzyme
-
Liao, S. M. et al. A kinase-cyclin pair in the RNA polymerase II holoenzyme Nature 374, 193-196 (1995)
-
(1995)
Nature
, vol.374
, pp. 193-196
-
-
Liao, S.M.1
-
77
-
-
0035336896
-
Transcriptional activation: Risky business
-
Tansey, W. P. Transcriptional activation: risky business. Genes Dev. 15, 1045-1050 (2001)
-
(2001)
Genes Dev.
, vol.15
, pp. 1045-1050
-
-
Tansey, W.P.1
-
79
-
-
0035979738
-
Regulation of transcriptional activation domain function by ubiquitin
-
Salghetti, S. E., Caudy, A. A., Chenoweth, J. G. & Tansey, W. P. Regulation of transcriptional activation domain function by ubiquitin. Science 293, 1651-1653 (2001). Showed that ubiquitylation of a transcription factor bearing the prototypical VP16 activation domain can be required for transcriptional activation.
-
(2001)
Science
, vol.293
, pp. 1651-1653
-
-
Salghetti, S.E.1
Caudy, A.A.2
Chenoweth, J.G.3
Tansey, W.P.4
-
80
-
-
0035853037
-
RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: A negative feedback circuit
-
Xie, Y. & Varshavsky, A. RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuit. Proc. Natl Acad. Sci. USA 98, 3056-3061 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 3056-3061
-
-
Xie, Y.1
Varshavsky, A.2
-
81
-
-
0032867676
-
The 26S proteasome: A molecular machine designed for controlled proteolysis
-
Voges, D., Zwickl, P. & Baumeister, W. The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu. Rev. Biochem. 68, 1015-1068 (1999).
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 1015-1068
-
-
Voges, D.1
Zwickl, P.2
Baumeister, W.3
-
82
-
-
0026681291
-
Alterations in a yeast protein resembling HIV Tat-binding protein relieve requirement for an acidic activation domain in GAL4
-
Swaffield, J. C., Bromberg, J. F. & Johnston, S. A. Alterations in a yeast protein resembling HIV Tat-binding protein relieve requirement for an acidic activation domain in GAL4. Nature 357, 698-700 (1992).
-
(1992)
Nature
, vol.357
, pp. 698-700
-
-
Swaffield, J.C.1
Bromberg, J.F.2
Johnston, S.A.3
-
83
-
-
0030464067
-
Isolation and characterization of SUG 2. A novel ATPase family component of the yeast 26S proteasome
-
Russell, S. J., Sathyanarayana, U. G. & Johnston, S. A. Isolation and characterization of SUG2. A novel ATPase family component of the yeast 26S proteasome. J. Biol. Chem. 271, 32810-32817 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 32810-32817
-
-
Russell, S.J.1
Sathyanarayana, U.G.2
Johnston, S.A.3
-
84
-
-
0028890360
-
A highly conserved ATPase protein as a mediator between acidic activation domains and the TATA-binding protein
-
Swaffield, J. C., Melcher, K. & Johnston, S. A. A highly conserved ATPase protein as a mediator between acidic activation domains and the TATA-binding protein. Nature 374, 88-91 (1995).
-
(1995)
Nature
, vol.374
, pp. 88-91
-
-
Swaffield, J.C.1
Melcher, K.2
Johnston, S.A.3
-
85
-
-
0032404015
-
Proteasome-mediated degradation of the vitamin D receptor (VDR) and a putative role for SUG1 interaction with the AF-2 domain of VDR
-
Masuyama, H. & MacDonald, P. N. Proteasome-mediated degradation of the vitamin D receptor (VDR) and a putative role for SUG1 interaction with the AF-2 domain of VDR J. Cell. Biochem. 71, 429-440 (1998).
-
(1998)
J. Cell. Biochem.
, vol.71
, pp. 429-440
-
-
Masuyama, H.1
MacDonald, P.N.2
-
86
-
-
0012316186
-
Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1
-
vom Baur, E. et al. Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1. EMBO J. 15, 110-124 (1996).
-
(1996)
EMBO J.
, vol.15
, pp. 110-124
-
-
Vom Baur, E.1
-
87
-
-
0029739021
-
Mammalian Sug1 and c-Fos in the nuclear 26S proteasome
-
Wang, W., Chevray, P. M. & Nathans, D. Mammalian Sug1 and c-Fos in the nuclear 26S proteasome. Proc. Natl Acad. Sci. USA 93, 8236-8240 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8236-8240
-
-
Wang, W.1
Chevray, P.M.2
Nathans, D.3
-
88
-
-
0028930848
-
GAL4 interacts with TATA-binding protein and coactivators
-
Melcher, K. & Johnston, S. A. GAL4 interacts with TATA-binding protein and coactivators. Mol. Cell. Biol. 15, 2839-2848 (1995).
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2839-2848
-
-
Melcher, K.1
Johnston, S.A.2
-
89
-
-
0032711876
-
Multiple mammalian proteasomal ATPases, but not proteasome itself, are associated with TATA-binding protein and a novel transcriptional activator, TIP120
-
Makino, Y. et al. Multiple mammalian proteasomal ATPases, but not proteasome itself, are associated with TATA-binding protein and a novel transcriptional activator, TIP120, Genes Cells 4, 529-539 (1999)
-
(1999)
Genes Cells
, vol.4
, pp. 529-539
-
-
Makino, Y.1
-
90
-
-
0030739911
-
The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG 1, a subunit of the 26S proteasome and putative transcription factor
-
Weeda, G. et al. The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor. Nucleic Acids Res. 25, 2274-2283 (1997).
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 2274-2283
-
-
Weeda, G.1
-
91
-
-
0028282551
-
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II
-
Kim, Y. J., Bjorklund, S., Li, Y., Sayre, M. H. & Kornberg, R. D. A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II. Cell 77, 599-608 (1994).
-
(1994)
Cell
, vol.77
, pp. 599-608
-
-
Kim, Y.J.1
Bjorklund, S.2
Li, Y.3
Sayre, M.H.4
Kornberg, R.D.5
-
92
-
-
0035971226
-
Evidence that proteolysis of Gal4 cannot explain the transcriptional effects of proteasome ATPase mutations
-
Russell, S. J. & Johnston, S. A. Evidence that proteolysis of Gal4 cannot explain the transcriptional effects of proteasome ATPase mutations. J. Biol. Chem. 276, 9825-9831 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9825-9831
-
-
Russell, S.J.1
Johnston, S.A.2
-
93
-
-
0035947238
-
The particle of the proteasome is required for efficient transcription elongation by RNA polymerase II
-
Ferdous, A., Gonzalez, F., Sun, L. Kodadek, T. & Johnston, S. A. The 19S regulatory particle of the proteasome is required for efficient transcription elongation by RNA polymerase II. Mol. Cell 7, 981-991 (2001).
-
(2001)
Mol. Cell
, vol.7
, pp. 981-991
-
-
Ferdous, A.1
Gonzalez, F.2
Sun, L.3
Kodadek, T.4
Johnston, S.A.5
-
94
-
-
0029880348
-
Three functional classes of transcriptional activation domain
-
Blau, J. et al. Three functional classes of transcriptional activation domain. Mol. Cell. Biol. 16, 2044-2055 (1996).
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2044-2055
-
-
Blau, J.1
-
95
-
-
0033791447
-
Proteasomal proteomics: Identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes
-
Verma, R. et al. Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes. Mol. Biol. Cell 11, 3425-3439 (2000).
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 3425-3439
-
-
Verma, R.1
-
96
-
-
0031881688
-
The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain
-
Myers, L. C. et al. The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain. Genes Dev. 12, 45-54 (1998).
-
(1998)
Genes Dev.
, vol.12
, pp. 45-54
-
-
Myers, L.C.1
-
97
-
-
0030796436
-
SUG1, a component of the 26S proteasome, is an ATPase stimulated by specific RNAs
-
Makino, Y. et al. SUG1, a component of the 26S proteasome, is an ATPase stimulated by specific RNAs. J. Biol. Chem. 272, 23201-23205 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23201-23205
-
-
Makino, Y.1
-
98
-
-
0036469287
-
Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex
-
Albert, T. K. et al. Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex. EMBO J. 21, 355-364 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 355-364
-
-
Albert, T.K.1
-
99
-
-
0029084914
-
Elongin (SIII): A multisubunit regulator of elongation by RNA polymerase II
-
Aso, T., Lane, W. S., Conaway, J. W. & Conaway, R. C. Elongin (SIII): a multisubunit regulator of elongation by RNA polymerase II. Science 269, 1439-1443 (1995).
-
(1995)
Science
, vol.269
, pp. 1439-1443
-
-
Aso, T.1
Lane, W.S.2
Conaway, J.W.3
Conaway, R.C.4
-
100
-
-
0036123253
-
Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex
-
Mueller, C. L. & Jaehning, J. A. Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex. Mol. Cell. Biol. 22, 1971-1980 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1971-1980
-
-
Mueller, C.L.1
Jaehning, J.A.2
-
101
-
-
0028907874
-
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase
-
Huibregtse, J. M., Scheffner, M., Beaudenon, S. & Howley, P. M. A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc. Natl Acad. Sci. USA 92, 2563-2567 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 2563-2567
-
-
Huibregtse, J.M.1
Scheffner, M.2
Beaudenon, S.3
Howley, P.M.4
-
102
-
-
0032500682
-
TOM1p, a yeast hect-domain protein which mediates transcriptional regulation through the ADA/SAGA coactivator complexes
-
Saleh, A. et al. TOM1p, a yeast hect-domain protein which mediates transcriptional regulation through the ADA/SAGA coactivator complexes. J. Mol. Biol. 282, 933-946 (1998).
-
(1998)
J. Mol. Biol.
, vol.282
, pp. 933-946
-
-
Saleh, A.1
|