Altered hippocampal gene expression prior to the onset of spontaneous seizures in the rat post-status epilepticus model

European Journal of Neuroscience

Volumn 14, Issue 9, 2001, Pages 1475-1484

  Hendriksen, H ^a   Datson, Nicole A ^c   Ghijsen, Wim E J M ^a   Van Vliet, Erwin A ^a   Lopes da Silva, Fernando H ^a,b   Gorter, Jan A ^a,b   Vreugdenhil, Erno ^c  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b STICHTING EPILEPSIE INSTELLINGEN NEDERLAND SEIN   (Netherlands)

^c LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Epileptogenesis; Hippocampus; Latent period; mRNA; SAGE; Tag

Indexed keywords

MESSENGER RNA; PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CELL LOSS; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE MODEL; EPILEPTIC STATE; EPILEPTOGENESIS; GENE EXPRESSION; GENETIC ANALYSIS; GLIA CELL; GLIOSIS; HIPPOCAMPUS; HISTOLOGY; IN SITU HYBRIDIZATION; LATENT PERIOD; MALE; MOSSY FIBER; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; RAT; RNA TRANSCRIPTION; SEIZURE; TIME;

ANIMALS; BASE SEQUENCE; CLUSTERIN; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ELECTROENCEPHALOGRAPHY; EPILEPSY; EPILEPSY, TEMPORAL LOBE; GENE EXPRESSION REGULATION; GENETIC MARKERS; GLYCOPROTEINS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE POTENTIALS; MOLECULAR CHAPERONES; NERVE DEGENERATION; NERVE REGENERATION; NERVE TISSUE PROTEINS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; STATUS EPILEPTICUS; TIME FACTORS; TRANSCRIPTION, GENETIC; TUBULIN; UP-REGULATION;

EID: 0035783957     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0953-816X.2001.01778.x     Document Type: Article

References (45)

1. Annegers, J.F., Hauser, W.A., Shirts, S.B. & Kurland, L.T. (1987) Factors prognostic of unprovoked seizures after febrile convulsions. N. Engl. J. Med., 316, 493-498.
2. Aronica, E., van Vliet, E.A., Hendriksen, H., Troost, D., Lopes da Silva, F.H. & Gorter, J.A. (2001a) Cystatin C, a cysteine protease inhibitor, is persistently upregulated in neurons and glia in a rat model of mesial temporal lobe epilepsy. Eur. J. Neurosci., 14, xxx-xxx.
3. Aronica, E., van Vliet, E.A., Mayboroda, O.A., Troost, D., Lopes da Silva, F.H. & Gorter, J.A. (2000) Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy. Eur. J. Neurosci., 12, 2333-2344.
4. Aronica, E., Yankaya, B., Troost, D., van Vliet, E.A., Lopes da Silva, F.H. & Gorter, J.A. (2001b) Induction of neonatal sodium channel II and III alpha isoform mRNAs in neurons and microglia after status epilepticus in the rat hippocampus. Eur. J. Neurosci., 13, 1261-1266.
5. Bennett, M.V., Pellegrini-Giampietro, D.E., Gorter, J.A., Aronica, E., Connor, J.A. & Zukin, R.S. (1996) The GluR2 hypothesis: Ca(++)-permeable AMPA receptors in delayed neurodegeneration. Cold Spring Harbor Symp. Quant. Biol., 61, 373-384.
6. Bertram, E.H. & Cornett, J. (1993) The ontogeny of seizures in a rat model of limbic epilepsy: Evidence for a kindling process in the development of chronic spontaneous seizures. Brain Res., 625, 295-300.
7. Bettuzzi, S., Hiipakka, R.A., Gilna, P. & Liao, S.T. (1989) Identification of an androgen-repressed mRNA in rat ventral prostate as coding for sulphated glycoprotein 2 by cDNA cloning and sequence analysis. Biochem. J., 257, 293-296.
8. Buzsaki, G., Freund, T.F., Bayardo, F. & Somogyi, P. (1989) Ischemia-induced changes in the electrical activity of the hippocampus. Exp. Brain Res., 78, 268-278.
9. Datson, N.A., van der Perk, J., de Kloet, E.R. & Vreugdenhil, E. (2001a) Identification of corticosteroid-responsive genes in rat hippocampus using serial analysis of gene expression. Eur. J. Neurosci., 14, 675-689.
10. Datson, N.A., van der Perk, J., de Kloet, E.R. & Vreugdenhil, E. (2001b) Expression profile of 30 000 genes in rat hippocampus using SAGE. Hippocampus, 11, 430-444.
11. Datson, N.A., van der Perk-de Jong, J., van den Berg, M.P., de Kloet, E.R. & Vreugdenhil, E. (1999) MicroSAGE: A modified procedure for serial analysis of gene expression in limited amounts of tissue. Nucl. Acids Res., 27, 1300-1307.
12. Du, F., Eid, T., Lothman, E.W., Kohler, C. & Schwarcz, R. (1995) Preferential neuronal loss in layer III of the medial entorhinal cortex in rat models of temporal lobe epilepsy. J. Neurosci., 15, 6301-6313.
13. Fernandez, G., Effenberger, O., Vinz, B., Steinlein, O., Elger, C.E., Dohring, W. & Heinze, H.J. (1998) Hippocampal malformation as a cause of familial febrile convulsions and subsequent hippocampal sclerosis. Neurology, 50, 909-917.
14. Ginzburg, I., Teichman, A., Griffin, W.S. & Littauer, U.Z. (1986) Differential expression of alpha-tubulin mRNA in rat cerebellum as revealed by in situ hybridization. FEBS Letts., 194, 161-164.
15. Gonçalves Pereira, P.M., Lucassen, P.J., van Vliet, E.A., Lopes da Silva, F.H. & Gorter, J.A. (2000) Spatio-temporal evolution of cell death in the hippocampus and entorhinal cortex in the post-status epilepticus model. Eur. J. Neurosci., 12, 210.
16. Gorter, J.A., Van Vliet, E.A., Aronica, E. & Lopes da Silva, F.H. (2001a) Progression of spontaneous seizures after status epilepticus is associated with mossy fibre sprouting and extensive bilateral loss of hilar parvalbumin and somatostatin-immunoreactive neurons. Eur. J. Neurosci., 13, 657-669.
17. Gorter, J.A., van Vliet, E.A., Aronica, E. & Lopes da Silva, F.H. (2001b) Long-lasting increased excitability differs in dentate gyrus versus CA1 in freely moving chronic epileptic rats after electrically induced status epilepticus. Hippocampus, in press.
18. Gunnersen, J.M., Spirkoska, V., Smith, P.E., Danks, R.A. & Tan, S.S. (2000) Growth and migration markers of rat C6 glioma cells identified by serial analysis of gene expression. Glia, 32, 146-154.
19. Hendriksen, H., Kamphuis, W. & Lopes da Silva, F.H. (1997) Changes in voltage-dependent calcium channel alpha1-subunit mRNA levels in the kindling model of epileptogenesis. Brain Res. Mol. Brain Res., 50, 257-266.
20. Hevroni, D., Rattner, A., Bundman, M., Lederfein, D., Gabarah, A., Mangelus, M., Silverman, M.A., Kedar, H., Naor, C., Kornuc, M., Hanoch, T., Seger, R., Theill, L.E., Nedivi, E., Richter-Levin, G. & Citri, Y. (1998) Hippocampal plasticity involves extensive gene induction and multiple cellular mechanisms. J. Mol. Neurosci., 10, 75-98.
21. Kamphuis, W., De Rijk, T.C., Talamini, L.M. & Lopes da Silva, F.H. (1994) Rat hippocampal kindling induces changes in the glutamate receptor mRNA expression patterns in dentate granule neurons. Eur. J. Neurosci., 6, 1119-1127.
22. Kawai, J., Shinagawa, A., Shibata, K., Yoshino, M., Itoh, M., Ishii, Y., Arakawa, T., Hara, A., Fukunishi, Y., Konno, H., Adachi, J., Fukuda, S., Aizawa, K., Izawa, M., Nishi, K., Kiyosawa, H., Kondo, S., Yamanaka, I., Saito, T., Okazaki, Y., Gojobori, T., Bono, H., Kasukawa, T., Saito, R., Kadota, K., Matsuda, H.A., Ashburner, M., Batalov, S., Casavant, T., Fleischmann, W., Gaasterland, T., Gissi, C., King, B., Kochiwa, H., Kuehl, P., Lewis, S., Matsuo, Y., Nikaido, I., Pesole, G., Quackenbush, J., Schriml, L.M., Staubli, F., Suzuki, R., Tomita, M., Wagner, L., Washio, T., Sakai, K., Okido, T., Furuno, M., Aono, H., Baldarelli, R., Barsh, G., Blake, J., Boffelli, D., Bojunga, N., Carninci, P., de Bonaldo, M.F., Brownstein, M.J., Bult, C., Fletcher, C., Fujita, M., Gariboldi, M., Gustincich, S., Hill, D., Hofmann, M., Hume, D.A., Kamiya, M., Lee, N.H., Lyons, P., Marchionni, L., Mashima, J., Mazzarelli, J., Mombaerts, P., Nordone, P., Ring, B., Ringwald, M., Rodriguez, I., Sakamoto, N., Sasaki, H., Sato, K., Schonbach, C., Seya, T., Shibata, Y., Storch, K.F., Suzuki, H., Toyo-oka, K., Wang, K.H., Weitz, C., Whittaker, C., Wilming, L., Wynshaw-Boris, A., Yoshida, K., Hasegawa, Y., Kawaji, H., Kohtsuki, S. & Hayashizaki, Y. (2001) Functional annotation of a full-length mouse cDNA collection. The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium. Functional annotation meeting. Nature, 409, 685-690.
23. Kenzelmann, M. & Muhlemann, K. (1999) Substantially enhanced cloning efficiency of SAGE (Serial Analysis of Gene Expression) by adding a heating step to the original protocol. Nucl. Acids Res., 27, 917-918.
24. Khrestchatisky, M., Ferhat, L., Charton, G., Bernard, A., Pollard, H., Represa, A. & Ben-Ari, Y. (1995) Molecular correlates between reactive and developmental plasticity in the rat hippocampus. J. Neurobiol., 26, 426-436.
25. Kingham, P.J. & Pocock, J.M. (2001) Microglial secreted cathepsin B induces neuronal apoptosis. J. Neurochem., 76, 1475-1484.
26. Lalioti, M.D., Mirotsou, M., Buresi, C., Peitsch, M.C., Rossier, C., Ouazzani, R., Baldy-Moulinier, M., Bottani, A., Malafosse, A. & Antonarakis, S.E. (1997) Identification of mutations in cystatin B, the gene responsible for the Unverricht-Lundborg type of progressive myoclonus epilepsy (EPM1). Am. J. Hum. Genet., 60, 342-351.
27. Lemischka, I.R., Farmer, S., Racaniello, V.R. & Sharp, P.A. (1981) Nucleotide sequence and evolution of a mammalian alpha-tubulin messenger RNA. J. Mol. Biol., 151, 101-120.
28. Lopes da Silva, F.H., Kamphuis, W., Titulaer, M., Vreugdenhil, M. & Wadman, W.J. (1995) An experimental model of progressive epilepsy: The development of kindling of the hippocampus of the rat. Ital. J. Neurol. Sci., 16, 45-57.
29. McNamara, J.O. & Puranam, R.S. (1998) Epilepsy genetics: An abundance of riches for biologists. Curr. Biol., 8, R168-R170.
30. Nissinen, J., Halonen, T., Koivisto, E. & Pitkanen, A. (2000) A new model of chronic temporal lobe epilepsy induced by electrical stimulation of the amygdala in rat. Epilepsy Res., 38, 177-205.
31. Nitatori, T., Sato, N., Waguri, S., Karasawa, Y., Araki, H., Shibanai, K., Kominami, E. & Uchiyama, Y. (1995) Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J. Neurosci., 15, 1001-1011.
32. Noebels, J.L., Sutherland, M.L., Nahm, W.K. & DiPasquale, E. (1996) Molecular and cellular plasticity in developing epileptic brain. Cold Spring Harbor Symp. Quant. Biol., 61, 319-326.
33. Pellegrini-Giampietro, D.E., Gorter, J.A., Bennett, M.V. & Zukin, R.S. (1997) The GluR2 (GluR-B) hypothesis: Ca(2+)-permeable AMPA receptors in neurological disorders. Trends Neurosci., 20, 464-470.
34. Pennacchio, L.A., Lehesjoki, A.E., Stone, N.E., Willour, V.L., Virtaneva, K., Miao, J., D'Amato, E., Ramirez, L., Faham, M., Koskiniemi, M., Warrington, J.A., Norio, R., de la Chapelle, A., Cox, D.R. & Myers, R.M. (1996) Mutations in the gene encoding cystatin B in progressive myoclonus epilepsy (EPM1). Science, 271, 1731-1734.
35. Pulsinelli, W.A. (1985) Selective neuronal vulnerability: Morphological and molecular characteristics. Prog. Brain Res., 63, 29-37.
36. Puranam, R.S. & McNamara, J.O. (1999) Seizure disorders in mutant mice: Relevance to human epilepsies. Curr. Opin. Neurobiol., 9, 281-287.
37. Sloviter, R.S. (1982) A simplified Timm stain procedure compatible with formaldehyde fixation and routine paraffin embedding of rat brain. Brain Res. Bull., 8, 771-774.
38. Sloviter, R.S. & Pedley, T.A. (1998) Subtle hippocampal malformation: Importance in febrile seizures and development of epilepsy [editorial; comment]. Neurology, 50, 846-849.
39. Steward, O., Torre, E.R., Tomasulo, R. & Lothman, E. (1991) Neuronal activity up-regulates astroglial gene expression. Proc. Natl. Acad. Sci. USA, 88 , 6819-6823.
40. Sun, Q. (1989) Growth stimulation of 3T3 fibroblasts by cystatin. Exp. Cell Res., 180, 150-160.
41. Velculescu, V.E., Zhang, L., Vogelstein, B. & Kinzler, K.W. (1995) Serial analysis of gene expression. Science, 270, 484-487.
42. Velculescu, V.E., Zhang, L., Zhou, W., Vogelstein, J., Basrai, M.A., Bassett, D.E. Jr, Hieter, P., Vogelstein, B. & Kinzler, K.W. (1997) Characterization of the yeast transcriptome. Cell, 88, 243-251.
43. Welle, S., Bhatt, K. & Thornton, C.A. (1999) Inventory of high-abundance mRNAs in skeletal muscle of normal men. Genome Res., 9, 506-513.
44. Yamashima, T. (2000) Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates. Prog. Neurobiol., 62, 273-295.
45. Zhang, L., Zhou, W., Velculescu, V.E., Kern, S.E., Hruban, R.H., Hamilton, S.R., Vogelstein, B. & Kinzler, K.W. (1997) Gene expression profiles in normal and cancer cells. Science, 276, 1268-1272.