Energy depletion in seizures: Anaplerosis as a strategy for future therapies

Neuropharmacology

Volumn 69, Issue , 2013, Pages 96-104

  Kovac, Stjepana ^a,b   Abramov, Andrey Y ^a   Walker, Matthew C ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Anaplerosis; ATP; Ketogenic diet; Pyruvate; Seizure; TCA cycle

Indexed keywords

2 OXOGLUTARIC ACID; ACETYL COENZYME A; ADENOSINE TRIPHOSPHATE; CITRATE SYNTHASE; MALIC ACID; OXALOACETIC ACID; PYRUVATE CARBOXYLASE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUCCINIC ACID; SUCCINYL COENZYME A;

CELL DEATH; CITRIC ACID CYCLE; COGNITIVE DEFECT; EPILEPSY; EPILEPTOGENESIS; GENE MUTATION; HUMAN; KETOGENIC DIET; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; REVIEW; SEIZURE; TRANSLATIONAL RESEARCH;

ADENOSINE TRIPHOSPHATE; ANIMALS; CITRIC ACID CYCLE; ENERGY METABOLISM; HUMANS; KETOGENIC DIET; NEURONS; PYRUVIC ACID; SEIZURES;

EID: 84875255103     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.05.012     Document Type: Review

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