Human morbid genetics revisited: Relevance of epigenetics

Trends in Genetics

Volumn 17, Issue 3, 2001, Pages 142-146

  Petronis, A ^a  

^a CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASE COURSE; DISEASE TRANSMISSION; GENE EXPRESSION REGULATION; GENETIC DISORDER; HUMAN; MONOZYGOTIC TWINS; ONSET AGE; PRIORITY JOURNAL; REVIEW; SEX DIFFERENCE;

AGE OF ONSET; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETICS, MEDICAL; HUMANS; MALE; TWINS, MONOZYGOTIC;

EID: 0035283058     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-9525(00)02213-7     Document Type: Review

References (53)

1. The future of genetic studies of complex human diseases
2. Leaving Kansas ... finding genes in 1997
3. Migration patterns and breast carcinoma
4. Über den einfluß des genotypus auf das phänotypische auftreten eines einzelnen gens
5. A logic of disease
6. Inflammatory bowel disease
7. Late-onset schizophrenia and very-late-onset schizophrenia-like psychosis: An international consensus
8. Psychopathology in women and men: Focus on female hormones
9. Sex-based differences in gene transmission and gene expression
10. The genetics of asthma. Maternal effects in atopic disease
11. Patterns of maternal transmission in bipolar affective disorder
12. Higher risk of seizures in offspring of mothers than of fathers with epilepsy
13. Parental origin of diabetes-associated HLA types in sibling pairs with type I diabetes
14. Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect
15. The analysis of parental origin of alleles may detect susceptibility loci for complex disorders
16. Reproducibility and complications in gene searches: Linkage on chromosome 6, heterogeneity, association, and maternal inheritance in juvenile myoclonic epilepsy
17. Genetic studies of autistic disorder and chromosome 7
18. Age-dependent decline of symptoms of attention deficit hyperactivity disorder: Impact of remission definition and symptom type
19. Course of tic severity in Tourette syndrome: The first two decades
20. Full recovery from schizophrenia: The prognostic role of premorbid adjustment, symptoms at first admission, precipitating events and gender
21. Exploring and explaining epigenetic effects
22. Epigenetic effects in eukaryotic gene expression
23. DNA modification, differentiation, and transformation
24. Cytosine methylation and mammalian development
25. Mutagenic and epigenetic effects of DNA methylation
26. Epigenetic control of gene expression
27. Chromosomal elements conferring epigenetic inheritance
28. PCR-aided genomic sequencing of an X-linked CpG island: Methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability
29. Methylation dynamics, epigenetic fidelity and X chromosome structure
30. Epigenetic differences in genetically identical organisms
31. The inheritance of epigenetic defects
32. Are somatic cells inherently deficient in methylation metabolism? A proposed mechanism for DNA methylation loss, senescence and aging
33. Partial overlapping of binding sequences for steroid hormone receptors and DNaseI hypersensitive sites in the rabbit uteroglobin gene region
34. Histone acetylation decreased by estradiol in the MCF-7 human mammary cancer cell line
35. Increased acetylation of histones at an early stage of oestradiol-mediated gene activation in the liver of immature chicks
36. Transcriptional control by steroid hormones
37. Genomic sequencing reveals a positive correlation between the kinetics of strand-specific DNA demethylation of the overlapping estradiol/glucocorticoid - Receptor binding sites and the rate of avian vitellogenin mRNA synthesis
38. Sexually dimorphic DNA demethylation in the promoter of the Slp (sex-limited protein) gene in mouse liver
39. Genomic imprinting: Review and relevance to human diseases
40. Gametic imprinting in mammals
41. Mechanisms of genomic imprinting
42. Propagating epigenetic states through meiosis: Where Mendel's gene is more than a DNA moiety
43. The Drosophila Fab-7 chromosomal element conveys epigenetic inheritance during mitosis and meiosis
44. Epigenetic control of transgene expression and imprinting by genotype-specific modifiers
45. Inheritance of allelic blueprints for methylation patterns
46. A theory of the evolutionary origins of psychosis
47. Mouse A9 cells containing single human chromosomes for analysis of genomic imprinting
48. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
49. DNA methylation and histone deacetylation in the control of gene expression: Basic biochemistry to human development and disease
50. Methylation profiles of genomic DNA of mouse developmental brain detected by restriction landmark genomic scanning (RLGS) method
51. Establishment of methylation-sensitive-representational difference analysis and isolation of hypo- and hypermethylated genomic fragments in mouse liver tumors