MicroRNA networks direct neuronal development and plasticity

Cellular and Molecular Life Sciences

Volumn 69, Issue 1, 2012, Pages 89-102

  Olde Loohuis, N F M ^a   Kos, A ^a   Martens, G J M ^a   Van Bokhoven, H ^a   Nadif Kasri, N ^a   Aschrafi, A ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Learning and memory; MicroRNA; Neurological diseases; Neuronal development; Synapse

Indexed keywords

MICRORNA; MICRORNA 104; MICRORNA 106B; MICRORNA 107; MICRORNA 124; MICRORNA 125B; MICRORNA 128; MICRORNA 132; MICRORNA 133B; MICRORNA 134; MICRORNA 137; MICRORNA 138; MICRORNA 146A; MICRORNA 146B; MICRORNA 181B; MICRORNA 219; MICRORNA 29; MICRORNA 298; MICRORNA 29A; MICRORNA 29B 1; MICRORNA 323; MICRORNA 328; MICRORNA 34C; MICRORNA 375; MICRORNA 378; MICRORNA 379; MICRORNA 451; MICRORNA 9; UNCLASSIFIED DRUG;

BIOGENESIS; CELL COMPARTMENTALIZATION; CELL MATURATION; CELLULAR DISTRIBUTION; COMPLEX FORMATION; DISEASE ASSOCIATION; DROSOPHILA; GENE EXPRESSION REGULATION; GENETIC CODE; HUMAN; LEARNING; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; MOLECULAR INTERACTION; NERVE CELL DIFFERENTIATION; NERVE CELL LESION; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NERVE FIBER; NONHUMAN; PROMOTER REGION; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; WORKING MEMORY;

ANIMALS; BRAIN; GENE EXPRESSION REGULATION; HUMANS; MICE; MICRORNAS; MODELS, BIOLOGICAL; NERVOUS SYSTEM DISEASES; NEUROGENESIS; NEURONAL PLASTICITY; NEURONS; PROTEIN BIOSYNTHESIS; RATS;

EID: 84856215758     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-011-0788-1     Document Type: Review

References (127)

1. MK Belmonte G Allen A Beckel-Mitchener LM Boulanger RA Carper SJ Webb 2004 Autism and abnormal development of brain connectivity J Neurosci 24 42 9228 9231 15496656 1:CAS:528:DC%2BD2cXpsVWgsrw%3D (Pubitemid 39426157)
2. K Yashiro TT Riday KH Condon AC Roberts DR Bernardo R Prakash RJ Weinberg MD Ehlers BD Philpot 2009 Ube3a is required for experience-dependent maturation of the neocortex Nat Neurosci 12 6 777 783 19430469 1:CAS:528: DC%2BD1MXls1CmtrY%3D
3. M Costa-Mattioli WS Sossin E Klann N Sonenberg 2009 Translational control of long-lasting synaptic plasticity and memory 2 Neuron 61 1 10 26 19146809 1:CAS:528:DC%2BD1MXhtlCnurs%3D
4. SA Manakov SG Grant AJ Enright 2009 Reciprocal regulation of microRNA and mRNA profiles in neuronal development and synapse formation BMC Genom 10 419
5. V Ambros 2008 The evolution of our thinking about microRNAs Nat Med 14 1036 1040 18841144 1:CAS:528:DC%2BD1cXht1Slu7rF
6. NJ Martinez RI Gregory 2010 MicroRNA gene regulatory pathways in the establishment and maintenance of ESC identity Cell Stem Cell 7 1 31 35 20621047 1:CAS:528:DC%2BC3cXps12ktro%3D
7. J Kim A Krichevsky Y Grad GD Hayes KS Kosik GM Church G Ruvkun 2004 Identification of many microRNAs that copurify with polyribosomes in mammalian neurons Proc Natl Acad Sci USA 101 1 360 365 14691248 1:CAS:528: DC%2BD2cXjvFaltQ%3D%3D (Pubitemid 38084255)
8. J Krol I Loedige W Filipowicz 2010 The widespread regulation of microRNA biogenesis, function and decay Nat Rev Genet 11 597 610 20661255 1:CAS:528:DC%2BC3cXhtVCnurzF
9. VN Kim 2005 MicroRNA biogenesis: coordinated cropping and dicing Nat Rev Mol Cell Biol 6 376 15852042 1:CAS:528:DC%2BD2MXjvF2jsLg%3D
10. AM Denli BBJ Tops RHA Plasterk RF Ketting GJ Hannon 2004 Processing of primary microRNAs by the microprocessor complex Nature 432 231 235 15531879 1:CAS:528:DC%2BD2cXpsF2gtrY%3D (Pubitemid 39545854)
11. RI Gregory KP Yan G Amuthan T Chendrimada B Doratotaj N Cooch R Shiekhatter 2003 The microprocessor complex mediates the genesis of microRNAs Nature 432 235 240
12. R Yi Y Qin IG Macara BR Cullen 2003 Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs Genes Dev 17 3011 3016 14681208 1:CAS:528:DC%2BD2cXhs1Shsg%3D%3D (Pubitemid 38040764)
13. C Gwizdek B Ossareh-Nazari AM Brownawell A Doglio E Bertrand IG Macara C Dargemont 2002 Exportin-5 mediates nuclear export of minihelix-containing RNAs J Biol Chem 278 8 5505 5508 12509441 (Pubitemid 36800789)
14. JE Babiarz JG Ruby Y Wang DP Bartel R Blelloch 2008 Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs Genes Dev 22 20 2773 2785 18923076 1:CAS:528:DC%2BD1cXht12ht73M
15. E Berezikov WJ Chung J Willis E Cuppen EC Lai 2007 Mammalian mirtron genes Mol Cell 28 2 328 336 17964270 1:CAS:528:DC%2BD2sXhtlShtr7J (Pubitemid 47600007)
16. K Okamura JW Hagen H Duan DM Tyler EC Lai 2007 The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila Cell 130 1 89 100 17599402 1:CAS:528:DC%2BD2sXotlGmtrY%3D (Pubitemid 47031325)
17. JG Ruby CH Jan DP Bartel 2007 Intronic microRNA precursors that bypass Drosha processing Nature 448 7149 83 86 17589500 1:CAS:528:DC%2BD2sXnt1entL8%3D (Pubitemid 47037009)
18. A Grishok Ae Pasquinelli D Conte N Li S Parrish I Ha DL Baillie A Fire G Ruvkun CC Mello 2001 Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing Cell 106 1 23 34 11461699 1:CAS:528:DC%2BD3MXlsVCqtrw%3D (Pubitemid 32709955)
19. RF Ketting SE Fischer E Bernstein T Sijen GJ Hannon Plasterk RH 2001 Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans Genes Dev 15 20 2654 2659 11641272 1:CAS:528:DC%2BD3MXnvVWksLY%3D (Pubitemid 32988876)
20. G Hutvagner J Mclachlan AE Pasquinelli E Balint T Tuschl PD Zamore 2001 A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA Science 293 5531 834 838 11452083 1:CAS:528:DC%2BD3MXlvVKksb4%3D (Pubitemid 32743968)
21. S Roush FJ Slack 2008 The let-7 family of microRNAs Trends Cell Biol 18 10 505 516 18774294 1:CAS:528:DC%2BD1cXhtFOlsbfE
22. Z Mourelatos J Dostie S Paushkin 2002 miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs Genes Dev 16 720 728 11914277 1:CAS:528:DC%2BD38XisVaju7c%3D (Pubitemid 34274041)
23. P Jin DC Zarnescu S Ceman M Nakamoto J Mowrey TA Jongens DL Nelson K Moses ST Warren 2004 Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway Nat Neurosci 7 2 113 117 14703574 1:CAS:528:DC%2BD2cXmvVGmtA%3D%3D (Pubitemid 38129786)
24. SM Hammond S Boettcher AA Caudy R Kobayashi GJ Hannon 2001 Argonaute2, a link between genetic and biochemical analysis of RNAi Science 293 5532 1146 1150 11498593 1:CAS:528:DC%2BD3MXmtVWqtLo%3D (Pubitemid 32758097)
25. D Cifuentes H Xue DW Taylor H Patnode Y Mishima S Cheloufi E Ma S Mane GJ Hannon ND Lawson SA Wolfe AJ Giraldez 2010 A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity Science 328 5986 1694 1698 20448148 1:CAS:528:DC%2BC3cXnvVektbs%3D
26. E Huntzinger E Izaurralde 2011 Gene silencing by microRNAs: contributions of translational repression and mRNA decay Nat Rev Genet 12 2 99 110 21245828 1:CAS:528:DC%2BC3MXmsVelsw%3D%3D
27. M Wakiyama K Takimoto O Ohara S Yokoyama 2007 Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system Genes Dev 21 1857 1862 17671087 1:CAS:528:DC%2BD2sXps1alsr4%3D (Pubitemid 47204925)
28. G Mathonnet MR Fabion YV Svitkin A Parsyan L Huck T Murata S Biffo WC Merrich E Darzynkiewicz RS Pillai W Filipowicz TF Duchaine N Sonenberg 2007 MicroRNA inhibition of translation initiating in vitro by targeting the cap-binding complex eIF4F Science 317 1764 1767 17656684 1:CAS:528: DC%2BD2sXhtVGmsLbO (Pubitemid 47461843)
29. N Sonenberg TE Dever 2003 Eukaryotic translation initiation factors and regulators Curr Opin Struct Biol 13 1 56 63 12581660 1:CAS:528: DC%2BD3sXhtVGmsbc%3D (Pubitemid 36170255)
30. M Bak A Silahtaroglu M Meller 2008 MicroRNA expression in the adult mouse central nervous system RNA 14 432 444 18230762 1:CAS:528:DC%2BD1cXivFaqs7g%3D (Pubitemid 351397808)
31. X He Q Zhang Y Liu X Pan 2007 Cloning and identification of novel microRNAs from rat hippocampus Acta Biochim Biophys Sin 39 9 708 714 17805466 1:CAS:528:DC%2BD2sXhtF2hsbzL (Pubitemid 47437948)
32. L Olsen M Klausen L Helboe FC Nielsen T Werge 2009 MicroRNAs show mutually exclusive expression patterns in the brain of adult male rats PLoS One 4 10 1 7
33. G Lugli VI Torvik J Larson NR Smalheiser 2008 Expression of microRNAs and their precursors in synaptic fractions of adult mouse forebrain J Neurochem 106 650 661 18410515 1:CAS:528:DC%2BD1cXovFWgtL0%3D
34. MJ Kye T Liu SF Levy 2007 Somatodendritic microRNAs identified by laser capture and multiplex RT-PCR RNA 13 1224 1234 17592044 1:CAS:528: DC%2BD2sXos1GhsL0%3D (Pubitemid 47080468)
35. U Hengst LJ Cox EZ Macosko SR Jaffrey 2006 Functional and selective RNA interference in developing axons and growth cones J Neurosci 26 21 5727 5732 16723529 1:CAS:528:DC%2BD28XlsVOjtr4%3D (Pubitemid 44315264)
36. O Natera-Naranjo A Aschrafi AE Gioio BB Kaplan 2010 Identification and quantitative analyses of microRNAs located in the distal axons of sympathetic neurons RNA 16 8 1516 1529 20584895 1:CAS:528:DC%2BC3cXhtVCltL3N
37. A Aschrafi AD Schwechter MG Mameza O Natera-Naranjo AE Gioio BB Kaplan 2008 MicroRNA-338 regulates local cytochrome c oxidase IV mRNA levels and oxidative phosphorylation in the axons of sympathetic neurons J Neurosci 28 47 12581 12590 19020050 1:CAS:528:DC%2BD1cXhsVGmtLfM
38. BB Kaplan AE Gioio M Hillefors A Aschrafi 2009 Axonal protein synthesis and the regulation of local mitochondrial function Results Probl Cell Differ 48 225 242 19343315 1:CAS:528:DC%2BC3cXhsF2rtLrN
39. LJ Cox U Hengst NG Gurskaya KA Lukyanov SR Jaffrey 2008 Intra-axonal translation and retrograde trafficking of CREB promotes neuronal survival Nat Cell Biol 10 2 149 159 18193038 1:CAS:528:DC%2BD1cXhs1Kiu78%3D (Pubitemid 351194044)
40. DS Campbell CE Holt 2001 Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation Neuron 32 6 1013 1026 11754834 1:CAS:528:DC%2BD38XitlahsA%3D%3D (Pubitemid 34075393)
41. DS Campbell AG Regan JS Lopez D Tannahill WA Harris CE Holt 2001 Semaphorin 3A elicits stage-dependent collapse, turning, and branching in Xenopus retinal growth cones J Neurosci 21 21 8538 8547 11606642 1:CAS:528:DC%2BD3MXnvVeqsb0%3D (Pubitemid 33051452)
42. KM Leung FP Horck AC Lin R Allison N Standart CE Holt 2006 Asymmetrical beta-actin mRNA translation in growth cones mediates attractive turning to netrin-1 Nat Neurosci 9 10 1247 1256 16980963 1:CAS:528:DC%2BD28XhtVSgu7fI (Pubitemid 44454266)
43. GL Ming ST Wong J Henley XB Yuan HJ Song NC Spitzer MM Poo 2002 Adaptation in the chemotactic guidance of nerve growth cones Nature 417 6887 411 418 11986620 1:CAS:528:DC%2BD38XjvVersrg%3D (Pubitemid 34563528)
44. X Zhang MM Poo 2002 Localized synaptic potentiation by BDNF requires local protein synthesis in the developing axon Neuron 36 4 675 688 12441056 1:CAS:528:DC%2BD38Xpt1Kgs7o%3D (Pubitemid 35350850)
45. A Aschrafi O Natera-Naranjo AE Gioio BB Kaplan 2010 Regulation of axonal trafficking of cytochrome c oxidase IV mRNA Mol Cell Neurosci 43 4 422 430 20144716 1:CAS:528:DC%2BC3cXjtVSgtr4%3D
46. Y Zhang K Tohyama JK Winterbottom NS Haque M Schachner AR Lieberman PN Anderson 2001 Correlation between putative inhibitory molecules at the dorsal root entry zone and failure of dorsal root axonal regeneration Mol Cell Neurosci 17 3 444 459 11273641 1:CAS:528:DC%2BD3MXitFymtL0%3D (Pubitemid 32289848)
47. S Hanz E Perlson D Willis JQ Zheng R Massarwa JJ Huerta M Koltzenburg M Kohler J Van-Minnen JL Twiss M Fainzilber 2003 Axoplasmic importins enable retrograde injury signaling in lesioned nerve Neuron 40 6 1095 1104 14687545 1:CAS:528:DC%2BD2cXhtVGrug%3D%3D (Pubitemid 38032787)
48. S Schacher F Wu 2002 Synapse formation in the absence of cell bodies requires protein synthesis J Neurosci 22 5 1831 1839 11880512 1:CAS:528:DC%2BD38XhvValurs%3D (Pubitemid 35386301)
49. V Beaumont N Zhong R Fletcher RC Froemke RS Zucker 2001 Phosphorylation and local presynaptic protein synthesis in calcium- and calcineurin-dependent induction of crayfish long-term facilitation Neuron 32 3 489 501 11709159 1:CAS:528:DC%2BD3MXovVeht70%3D (Pubitemid 33082049)
50. KC Martin A Casadio H Zhu E Yaping JC Rose M Chen CH Bailey ER Kandel 1997 Synapse-specific, long-term facilitation of aplysia sensory to motor synapses: a function for local protein synthesis in memory storage Cell 91 7 927 938 9428516 1:CAS:528:DyaK1cXjtVKjtQ%3D%3D (Pubitemid 28028772)
51. K Si M Giustetto A Etkin R Hsu AM Janisiewicz MC Miniaci JH Kim H Zhu ER Kandel 2003 A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia Cell 115 7 893 904 14697206 1:CAS:528:DC%2BD2cXhsFCnuw%3D%3D (Pubitemid 38058500)
52. DO Wang SM Kim Y Zhao H Hwang SK Miura WS Sossin KC Martin 2009 Synapse- and stimulus-specific local translation during long-term neuronal plasticity Science 324 5934 1536 1540 19443737 1:CAS:528:DC%2BD1MXnsFOrsLg%3D
53. JF Guzowski GL Lyford GD Stevenson FP Houston JL Mcgaugh PF Worley CA Barnes 2000 Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory J Neurosci 20 11 3993 4001 10818134 1:CAS:528:DC%2BD3cXjsFeltb4%3D (Pubitemid 30365669)
54. MA Sutton HT Ito P Cressy C Kempf JC Woo EM Schuman 2006 Miniature neurotransmission stabilizes synaptic function via tonic suppression of local dendritic protein synthesis Cell 125 4 785 799 16713568 1:CAS:528: DC%2BD28XltlSkt7Y%3D
55. PW Vanderklish GM Edelman 2005 Differential translation and fragile X syndrome Genes Brain Behavior 4 6 360 384 1:CAS:528:DC%2BD2MXhtVemt73E (Pubitemid 41192448)
56. MA Sutton EM Schuman 2006 Dendritic protein synthesis, synaptic plasticity, and memory Cell 127 49 58 17018276 1:CAS:528:DC%2BD28XhtFSitr%2FO (Pubitemid 44466643)
57. M Costa-Mattioli WS Sossin E Klann N Sonenberg 2009 Translational control of long-lasting synaptic plasticity and memory Neuron 61 10 26 19146809 1:CAS:528:DC%2BD1MXhtlCnurs%3D
58. JD Richter E Klann 2009 Making synaptic plasticity and memory last: mechanisms of translational regulation Genes Dev 23 1 11 19136621 1:CAS:528:DC%2BD1MXptFWlsg%3D%3D
59. CR Bramham DG Wells 2007 Dendritic mRNA: transport, translation and function Nat Neurosci 8 776 789 1:CAS:528:DC%2BD2sXhtVKht7%2FK (Pubitemid 47462112)
60. A Aschrafi BA Cunningham GM Edelman PW Vanderklish 2005 The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain PNAS 102 6 2180 2185 15684045 1:CAS:528:DC%2BD2MXhvFGqs7c%3D (Pubitemid 40262032)
61. F Smart A Aschrafi A Atkins GC Owens J Pilotte BA Cunningham PW Vanderklish 2007 Two isoforms of the cold-inducible mRNA-binding protein RBM3 localize to dendrites and promote translation J Neurochem 101 5 1367 1379 17403028 1:CAS:528:DC%2BD2sXmsFensLg%3D (Pubitemid 46718826)
62. ER Kandel 2001 The molecular biology of memory storage: a dialog between genes and synapses Biosci Rep 21 5 477 522
63. DO Wang KC Martin RS Zukin 2010 Spatially restricting gene expression by local translation at synapses Trends Neurosci 33 4 173 182 20303187 1:CAS:528:DC%2BC3cXksVejs7w%3D
64. MM Poon SH Choi CAM Jamieson DH Geschwind KC Martin 2006 Identification of process-localized mRNAs from cultured rodent hippocampal neurons J Neurosci 26 51 13390 13399 17182790 1:CAS:528:DC%2BD2sXjvVCgtw%3D%3D (Pubitemid 46011650)
65. J Zhong T Zhang LM Bloch 2006 Dendritic mRNAs encode diversified functionalities in hippocampal pyramidal neurons BMC Neurosci 7 17 16503994
66. EW Khandjian ME Huot S Tremblay L Davidovic R Mazroui B Bardoni 2004 Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles Proc Natl Acad Sci 101 36 13357 13362 15329415 1:CAS:528:DC%2BD2cXnvFemsLw%3D (Pubitemid 39209670)
67. TH Davis TL Cuellar SM Koch AJ Barker BD Harfe MT Mcmanus EM Ullian 2008 Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus J Neurosci 28 17 4322 4330 18434510 1:CAS:528: DC%2BD1cXlsVWgsrs%3D
68. D De Pietri Tonelli JM Pulvers C Haffner EP Murchison GJ Hannon WB Huttner 2008 MiRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex Development 135 3911 3921 18997113
69. A Schaefer D O'carroll CL Tan D Hillman M Sugimori R Llinas P Greengard 2007 Cerebellar neurodegeneration in the absence of microRNAs J Exp Med 204 7 1553 1558 17606634 1:CAS:528:DC%2BD2sXnslylsr8%3D (Pubitemid 47048023)
70. KL Stark B Xu A Bagchi WS Lai H Liu R Hsu X Wan P Pavlidis AA Mills M Karayiorgou JA Gogos 2008 Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model Nat Genet 40 6 751 760 18469815 1:CAS:528:DC%2BD1cXmsVejsL0%3D (Pubitemid 351748862)
71. S Banjernee P Neveu KS Kosik 2009 A coordinated local translation control point at the synapse involving relief from silencing and MOV10 degradation Neuron 64 871 884
72. CS Park SJ Tang 2009 Regulation of microRNA expression by induction of bidirectional synaptic plasticity J Neurosci 38 50 56 1:CAS:528: DC%2BD1MXksFGhuro%3D
73. K Wibrand D Panja A Tiron ML Ofte KO Skaftnesmo CS Lee JTG Pena T Tuschl CR Bramham 2010 Differential regulation of mature and precursor microRNA expression by NMDA and metabotropic glutamate receptor activation during LTP in the adult dentate gyrus in vivo Eur J Neurosci 31 636 645 20384810
74. ST Magill XA Cambronne BW Luikart DT Lioy BH Leighton GL Westbrook G Mandel RH Goodman 2010 microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus PNAS 107 47 20382 20387 21059906 1:CAS:528:DC%2BC3cXhsFaju7fO
75. LC Cheng E Pastrana M Tavazoie F Doetsch 2009 miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche Nat Neurosci 12 4 399 408 19287386 1:CAS:528:DC%2BD1MXjtFCis70%3D
76. D Edbauer JR Neilson KA Foster CF Wang DP Seeburg MN Batterton T Tada BM Dolan PA Sharp M Sheng 2010 Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132 Neuron 65 3 373 384 20159450 1:CAS:528:DC%2BC3cXlt1Kmt70%3D
77. N Vo ME Klein O Varlamova DM Keller T Yamamoto RH Goodman S Impey 2005 A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis PNAS 102 45 16426 16431 16260724 1:CAS:528:DC%2BD2MXht1CgurjI (Pubitemid 41688930)
78. GM Schratt F Tuebing EA Nigh CG Kane ME Sabatini M Kiebler ME Greenberg 2006 A brain-specific microRNA regulates dendritic spine development Nature 439 16 283 289 16421561 1:CAS:528:DC%2BD28XkvF2mtA%3D%3D (Pubitemid 43128846)
79. J Gao WY Wang YW Mao J Graff JS Guan L Pan G Mak D Kim SC Su LH Tsai 2010 A novel pathway regulates memory and plasticity via SIRT1 and miR-134 Nature 466 7310 1105 1109 20622856 1:CAS:528:DC%2BC3cXos1aisLY%3D
80. Smrt RD, Szulwach KE, Pfeiffer RL, Li X, Guo W, Pathania M, Teng ZQ, Luo Y, Bordey A, Peng J, Zhao X (2010) MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase Mind Bomb-1. Stem cells 28(6):1060-1070
81. G Siegel G Obernosterer R Fiore M Oehman S Bicker M Christensen S Khydayberdiev PF Leuschner CJL Busch C Kane K Hubel F Dekker C Hedberg B Rengarajan C Drepper H Waldmann S Kauppinen ME Greenberg A Draguhn M Rehmsmeier J Martinez G Schratt 2009 A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis Nat Cell Biol 11 705 716 19465924 1:CAS:528:DC%2BD1MXms1als7k%3D
82. M Lagos-Quintana R Rauhut A Yalcin J Meyer W Lendeckel T Tuschl 2002 Identification of tissue-specific microRNAs from mouse Curr Biol 12 9 735 739 12007417 1:CAS:528:DC%2BD38XjsFygtb4%3D (Pubitemid 34455427)
83. J Silber AD Lim C Petritsch AI Persson AK Maunakea M Yu SR Vanderberg DG Ginzinger CD James JF Costello G Bergers WA Weiss A Alvarez-Buylla JG Hodgson 2008 miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells BMC Med 6 14 18577219
84. JY Yu KH Chung M Deo RC Thompson DL Turner 2008 MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation Exp Cell Res 314 2618 2633 18619591 1:CAS:528:DC%2BD1cXpslWlsbc%3D
85. S Impey M Davare A Lasiek D Fortin H Ando O Varlamova K Obrietan TR Soderling RH Goodman GA Wayman 2010 An activity-induced microRNA controls dendritic spine formation by regulating Rac1-PAK signaling Mol Cell Neurosci 43 146 156 19850129 1:CAS:528:DC%2BD1MXhs1Wgu7bI
86. Y Lee C Ahn J Han H Choi J Kim J Yim J Lee P Provost O Radmark S Kim VN Kim 2003 The nuclear RNase III Drosha initiates microRNA processing Nature 425 415 419 14508493 1:CAS:528:DC%2BD3sXnsV2kt7s%3D (Pubitemid 37187272)
87. A Schenck B Bardoni C Langmann N Harden JL Mandel A Giangrande 2003 CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein Neuron 38 6 887 898 12818175 1:CAS:528:DC%2BD3sXltFanu7g%3D (Pubitemid 36782381)
88. I Napoli V Mercaldo PP Boyl B Eleuteri F Zalfa S De Rubeis D Di Marino E Mohr M Massimi M Falconi W Witke M Costa-Mattioli N Sonenberg T Achsel C Bagni 2008 The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP Cell 134 6 1042 1054 18805096 1:CAS:528: DC%2BD1cXht1Sns7rJ
89. R Fiore S Khudayberdiev M Christensen G Siegel SW Flavell TK Kim ME Greenberg G Schratt 2009 Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels EMBO J 28 6 697 710 19197241 1:CAS:528:DC%2BD1MXhsVCrtrc%3D
90. M Christensen LA Larsen S Kauppinen G Schratt 2010 Recombinant adeno-associated virus-mediated microRNA delivery into the postnatal mouse brain reveals a role for miR-134 in dendritogenesis in vivo Front Neural Circuits 3 16 20126250
91. AM Krichevsky KC Sonntag O Isacson KS Kosik 2006 Specific microRNAs modulate embryonic stem cell-derived neurogenesis Stem Cells 24 4 857 864 16357340 1:CAS:528:DC%2BD28XhtFKiu73F (Pubitemid 44464719)
92. C Zhao G Sun S Li Y Shi 2009 A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination Nat Struct Mol Biol 16 4 365 371 19330006 1:CAS:528:DC%2BD1MXjslart70%3D
93. M Shibata D Kurokawa H Nakao T Ohmura S Aizawa 2008 MicroRNA-9 modulates Cajal-Retzius cell differentiation by suppressing Foxg1 expression in mouse medial pallium J Neurosci 28 41 10415 10421 18842901 1:CAS:528: DC%2BD1cXht1GksLfE
94. M Shibata H Nakao H Kiyonari T Abe S Aizawa 2011 MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors J Neurosci 31 9 3407 3422 21368052 1:CAS:528:DC%2BC3MXjtVahurw%3D
95. Ig Bruno R Karam L Huang A Bhardwaj CH Lou EY Shum HW Song MA Corbett WD Gifford J Gecz SL Pfaff MF Wilkinson 2011 Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay Mol Cell 42 4 500 510 21596314 1:CAS:528:DC%2BC3MXmsVChtbg%3D
96. MJ Parsons CH Grimm JL Paya-Cano K Sugden W Nietfeld H Lehrach LC Schalkwyk 2008 Using hippocampal microRNA expression differences between mouse inbred strains to characterise miRNA function Mammalian Genome 19 552 560 18594913 1:CAS:528:DC%2BD1cXhsVCksr%2FN
97. NR Smalheiser G Lugli AL Lenon JM Davis VI Torvik J Larson 2010 Olfactory discrimination training up-regulates and reorganizes expression of microRNAs in adult mouse hippocampus ASN Neuro 2 1 39 48 1:CAS:528:DC%2BC3cXivFSnsLg%3D
98. W Konopka A Kiryk M Novak M Herwerth JR Parkitna M Wawrzyniak A Kowarsch P Michaluk J Dzwonek T Arnsperger G Wilczynski M Merkenschlager FJ Theis G Kohr L Kaczmarek G Schutz 2010 MicroRNA loss enhances learning and memory in mice J Neurosci 30 44 14835 14842 21048142 1:CAS:528:DC%2BC3cXhsVGqtbjF
99. JG Hunsberger DR Austin G Chen HK Manji 2009 MicroRNAs in mental health: from biological underpinnings to potential therapies Neuromol Med 11 3 173 182 1:CAS:528:DC%2BD1MXhtF2jsrfL
100. DE Kuhn GJ Nuovo AV Terry Jr MM Martin GE Malana SE Sansom AP Pleister WD Beck E Head DS Feldman TS Elton 2010 Chromosome 21-derived microRNAs provide an etiological basis for aberrant protein expression in human Down syndrome brains J Biol Chem 285 2 1529 1543 19897480 1:CAS:528:DC%2BC3cXkvFCl
101. KE Szulwach X Li RD Smrt Y Li Y Luo L Lin NJ Santistevan W Li X Zhao P Jin 2010 Cross talk between microRNA and epigenetic regulation in adult neurogenesis J Cell Biol 189 1 127 141 20368621 1:CAS:528:DC%2BC3cXks1CntLw%3D
102. K Abu-Elneel T Liu FS Gazzaniga Y Nishimura DP Wall DH Geschwind K Lao SK Kosik 2008 Heterogeneous dysregulation of microRNAs across the autism spectrum Neurogenetics 9 153 161 18563458 1:CAS:528:DC%2BD1cXnvVOhsrk%3D
103. R Zhou P Yuan Y Wang JG Hunsberger A Elkahloun Y Wei P Damschroder-Williams J Du G Chen HK Manji 2009 Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers Neuropsychopharmacology 34 6 1395 1405 18704095 1:CAS:528: DC%2BD1MXksFagu7g%3D
104. H Tan H Li P Jin 2009 RNA-mediated pathogenesis in fragile X-associated disorders Neurosci Lett 466 2 103 108 19631721 1:CAS:528:DC%2BD1MXhtlWhu7rO
105. XL Xu Y Li F Wang FB Gao 2008 The steady-state level of the nervous-system-specific microRNA-124a is regulated by dFMR1 in Drosophila J Neurosci 28 46 11883 11889 19005053 1:CAS:528:DC%2BD1cXhsVarurnN
106. DO Perkins CD Jeffries LF Jarskog JM Thomson K Woods MA Newman JS Parker J Jin SM Hammond 2007 microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder Genome Biol 8 2
107. NJ Beveridge PA Tooney AP Carroll E Gardiner N Bowden RJ Scott N Tran I Dedova MJ Cairns 2008 Dysregulation of miRNA 181b in the temporal cortex in schizophrenia Hum Mol Genet 17 8 1156 1168 18184693 1:CAS:528: DC%2BD1cXktlSktbg%3D (Pubitemid 351494187)
108. J Kocerha MA Faghihi MA Lopez-Toledano J Huang AJ Ramsey MG Caron N Sales D Willoughby J Elmen HF Hansen H Orum S Kauppinen PJ Kenny C Wahlestedt 2009 MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction PNAS 106 9 3507 3512 19196972 1:CAS:528:DC%2BD1MXivFGks7w%3D
109. J Krützfeldt N Rajewsky R Braich KG Rajeev T Tuschl M Manoharan M Stoffel 2005 Silencing of microRNAs in vivo with 'antagomirs' Nature 438 7068 685 689 16258535
110. MA Faghihi M Zhang J Huang F Modarresi MA Van Der Brug MA Nalls MR Cookson G St-Laurent C Wahlestedt 2010 Evidence for natural antisense transcript-mediated inhibition of microRNA function Genome Biol 11 5
111. SS Hebert B De Strooper 2009 Alterations of the microRNA network cause neurodegenerative disease Trends Neurosci 32 4 199 206 19268374 1:CAS:528:DC%2BD1MXkt1Skt7k%3D
112. J Kim K Inoue J Ishii WB Vanti SV Voronov E Murchinson G Hannon A Albeliovish 2007 A microRNA feedback circuit in midbrain dopamine neurons Science 317 5842 1220 1224 17761882 1:CAS:528:DC%2BD2sXps12ms7Y%3D
113. MA Lewis E Quint AM Glazier H Fuchs MH De Angelis C Langford S Van Dongen C Abreu-Goodger M Piipari N Redshaw T Dalmay MA Moreno-Pelayo AJ Enright KP Steel 2009 An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice Nat Genet 41 5 614 618 19363478 1:CAS:528:DC%2BD1MXksVels70%3D
114. JF Abelson KY Kwan BJ O'roak DY Baek AA Stillman TM Morgan CA Mathews DL Pauls MR Rašin M Gunel NR Davis AG Ercan-Sencicek DH Guez JA Spertus JF Leckman LS Dure R Kurlan HS Singer DL Gilbert A Farhi A Louvi RP Lifton N Sestan MW State 2005 Sequence variants in SLITRK1 are associated with Tourette's syndrome Science 310 5746 317 320 16224024 1:CAS:528:DC%2BD2MXhtV2hurvP (Pubitemid 41457198)
115. P Rajasethupathy F Fiumara R Sheridan D Betel SV Puthanveettil JJ Russo C Sander T Tuschl E Kandel 2009 Characterization of small RNAs in Aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB Neuron 63 6 803 817 19778509 1:CAS:528:DC%2BD1MXhsVCjsrbM
116. H Kawashima T Numakawa E Kumamaru N Adachi H Mizuno M Ninomiya H Kunugi K Hashido 2010 Glucocorticoid attenuates brain-derived neurotrophic factor-dependent upregulation of glutamate receptors via the suppression of microRNA-132 expression Neuroscience 165 4 1301 1311 19958814 1:CAS:528:DC%2BC3cXnsFWnsA%3D%3D
117. Gaughwin P, Ciesla M, Yang H, Lim B, Brundin P (2011) Stage-specific modulation of cortical neuronal development by mmu-miR-134. Cerebral Cortex 21(8):1857-1869
118. K Abdelmohsen ER Hutchison EK Lee Y Kuwano MM Kim K Masuda S Srikantan SS Subaran BS Marasa MP Mattson M Gorospe 2010 miR-375 inhibits differentiation of neurites by lowering HuD levels Mol Cell Biol 30 17 4197 4210 20584986 1:CAS:528:DC%2BC3cXhtFyhtrfM
119. AN Packer Y Xing SQ Harper L Jones BL Davidson 2008 The bifunctional microRNA miR-9/miR-9*regulates REST and CoREST and is downregulated in Huntington's disease J Neurosci 28 53 14341 14346 19118166 1:CAS:528: DC%2BD1MXnsF2huw%3D%3D
120. M Shioya S Obayashi H Tabunoki K Arima Y Saito T Ishida J Satoh 2010 Aberrant microRNA expression in the brains of neurodegenerative diseases: miR-29a decreased in Alzheimer disease brains targets neurone navigator 3 Neuropathol Appl Neurobiol 36 4 320 330 20202123 1:CAS:528:DC%2BC3cXot1artL4%3D
121. SS Hébert K Horré L Nicolaï AS Papadopoulou W Mandemakers AN Silahtaroglu S Kauppinen A Delacourte B De Strooper 2008 Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression PNAS 105 17 6415 6420 18434550 (Pubitemid 351758360)
122. WX Wang BW Rajeev AJ Stromberg N Ren G Tang Q Huang I Rigoutsos PT Nelson 2008 The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1 J Neurosci 28 5 1213 1223 18234899 (Pubitemid 351186356)
123. RG Urdinguio AF Fernandez P Lopez-Nieva S Rossi D Huertas M Kulis CG Liu C Croce GA Calin M Esteller 2010 Disrupted microRNA expression caused by Mecp2 loss in a mouse model of Rett syndrome Epigenetics 5 7
124. V Boissonneault I Plante S Rivest P Provost 2009 MicroRNA-298 and microRNA-328 regulate expression of mouse beta-amyloid precursor protein-converting enzyme 1 J Biol Chem 284 4 1971 1981 18986979 1:CAS:528:DC%2BD1MXlvFaksw%3D%3D
125. Montag J, Hitt R, Opitz L, Schulz-Schaeffer W.J, Hunsmann G, Motzkus D (2009) Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease. Mol Neurodegen 4:36-42
126. E Huntzinger E Izaurralde 2011 Gene silencing by microRNAs: contributions of translational repression and mRNA decay Nat Rev Genet 12 2 99 110 21245828 1:CAS:528:DC%2BC3MXmsVelsw%3D%3D
127. S Vasudevan Y Tong JA Steitz 2007 Switching from repression to activation: microRNAs can up-regulate translation Science 318 1931 1934 18048652 1:CAS:528:DC%2BD2sXhsVGjsLbK