-
1
-
-
0036568229
-
Interhelical hydrogen bonds and spatial motifs in membrane proteins: Polar clamps and serine zippers
-
ADAMIAN, L. & LIANG, J. (2002). Interhelical hydrogen bonds and spatial motifs in membrane proteins: Polar clamps and serine zippers. Proteins 47(2), 209-218.
-
(2002)
Proteins
, vol.47
, Issue.2
, pp. 209-218
-
-
Adamian, L.1
Liang, J.2
-
2
-
-
4444252927
-
Controlling the folding efficiency of an integral membrane protein
-
ALLEN, S., CURRAN, A., TEMPLER, R., MEIJBERG, W. & BOOTH, P. (2004). Controlling the folding efficiency of an integral membrane protein. Journal of Molecular Biology 342(4), 1293-1304.
-
(2004)
Journal of Molecular Biology
, vol.342
, Issue.4
, pp. 1293-1304
-
-
Allen, S.1
Curran, A.2
Templer, R.3
Meijberg, W.4
Booth, P.5
-
3
-
-
4444363179
-
Folding kinetics of an alpha helical membrane protein in phospholipid bilayer vesicles
-
ALLEN, S., CURRAN, A., TEMPLER, R., MEIJBERG, W. & BOOTH, P. (2004). Folding kinetics of an alpha helical membrane protein in phospholipid bilayer vesicles. Journal of Molecular Biology 342(4), 1279-1291.
-
(2004)
Journal of Molecular Biology
, vol.342
, Issue.4
, pp. 1279-1291
-
-
Allen, S.1
Curran, A.2
Templer, R.3
Meijberg, W.4
Booth, P.5
-
4
-
-
0015859467
-
Principles that govern the folding of protein chains
-
ANFINSEN, C. B. (1973). Principles that govern the folding of protein chains. Science 181(4096), 223-230.
-
(1973)
Science
, vol.181
, Issue.4096
, pp. 223-230
-
-
Anfinsen, C.B.1
-
5
-
-
84865328335
-
Architectural and thermodynamic principles underlying intramembrane protease function
-
BAKER, R.P. & URBAN, S. (2012). Architectural and thermodynamic principles underlying intramembrane protease function. Nature Chemical Biology 8(9), 759-768.
-
(2012)
Nature Chemical Biology
, vol.8
, Issue.9
, pp. 759-768
-
-
Baker, R.P.1
Urban, S.2
-
6
-
-
39349083915
-
Adapting proteostasis for disease intervention
-
BALCH, W. E., MORIMOTO, R. I., DILLIN, A. & KELLY, J.W. (2008). Adapting proteostasis for disease intervention. Science 319(5865), 916-919.
-
(2008)
Science
, vol.319
, Issue.5865
, pp. 916-919
-
-
Balch, W.E.1
Morimoto, R.I.2
Dillin, A.3
Kelly, J.W.4
-
7
-
-
39649096540
-
Protein selfassembly and lipid binding in the folding of the potassium channel KcsA
-
BARRERA, F. N., RENART, M. L., POVEDA, J. A., DE KRUIJFF, B., KILLIAN, J.A. & GONZ'LEZ-ROS, J.M. (2008). Protein selfassembly and lipid binding in the folding of the potassium channel KcsA. Biochemistry 47(7), 2123-2133.
-
(2008)
Biochemistry
, vol.47
, Issue.7
, pp. 2123-2133
-
-
Barrera, F.N.1
Renart, M.L.2
Poveda, J.A.3
De Kruijff, B.4
Killian, J.A.5
Gonz'Lez-Ros, J.M.6
-
8
-
-
0028825579
-
The membrane topology of the rat sarcoplasmic and endoplasmic reticulum calcium ATPases by in vitro translation scanning
-
BAYLE, D., WEEKS, D. & SACHS, G. (1995). The membrane topology of the rat sarcoplasmic and endoplasmic reticulum calcium ATPases by in vitro translation scanning. Journal of Biological Chemistry 270(43), 25678-25684.
-
(1995)
Journal of Biological Chemistry
, vol.270
, Issue.43
, pp. 25678-25684
-
-
Bayle, D.1
Weeks, D.2
Sachs, G.3
-
9
-
-
0035947372
-
Impairment of the ubiquitin-proteasome system by protein aggregation
-
BENCE, N. F., SAMPAT, R.M. & KOPITO, R. R. (2001). Impairment of the ubiquitin-proteasome system by protein aggregation. Science 292(5521), 1552-1555.
-
(2001)
Science
, vol.292
, Issue.5521
, pp. 1552-1555
-
-
Bence, N.F.1
Sampat, R.M.2
Kopito, R.R.3
-
10
-
-
84890954073
-
Repurposing diflunisal for familial amyloid polyneuropathy: A randomized clinical trial
-
BERK, J. L., SUHR, O. B., OBICI, L., SEKIJIMA, Y., ZELDENRUST, S. R., YAMASHITA, T., HENEGHAN, M. A., GOREVIC, P. D., LITCHY, W. J., WIESMAN, J. F., NORDH, E., CORATO, M., LOZZA, A., CORTESE, A., ROBINSON-PAPP, J., COLTON, T., RYBIN, D. V., BISBEE, A. B., ANDO, Y., IKEDA, S., SELDIN, D. C., MERLINI, G., SKINNER, M., KELLY, J.W., DYCK, P. J. & DIFLUNISAL TRIAL, C. (2013). Repurposing diflunisal for familial amyloid polyneuropathy: A randomized clinical trial. Journal of the American Medical Association 310(24), 2658-2667.
-
(2013)
Journal of the American Medical Association
, vol.310
, Issue.24
, pp. 2658-2667
-
-
Berk, J.L.1
Suhr, O.B.2
Obici, L.3
Sekijima, Y.4
Zeldenrust, S.R.5
Yamashita, T.6
Heneghan, M.A.7
Gorevic, P.D.8
Litchy, W.J.9
Wiesman, J.F.10
Nordh, E.11
Corato, M.12
Lozza, A.13
Cortese, A.14
Robinson-Papp, J.15
Colton, T.16
Rybin, D.V.17
Bisbee, A.B.18
Ando, Y.19
Ikeda, S.20
Seldin, D.C.21
Merlini, G.22
Skinner, M.23
Kelly, J.W.24
Dyck, P.J.25
Diflunisal Trial, C.26
more..
-
11
-
-
46449109015
-
Structure and energetics of the hydrogen-bonded backbone in protein folding
-
BOLEN, D.W. & ROSE, G. D. (2008). Structure and energetics of the hydrogen-bonded backbone in protein folding. Annual Review of Biochemistry 77, 339-362.
-
(2008)
Annual Review of Biochemistry
, vol.77
, pp. 339-362
-
-
Bolen, D.W.1
Rose, G.D.2
-
13
-
-
0029564596
-
Intermediates in the folding of the membrane protein bacteriorhodopsin
-
BOOTH, P. J., FLITSCH, S. L., STERN, L. J., GREENHALGH, D. A., KIM, P.S. & KHORANA, H. G. (1995). Intermediates in the folding of the membrane protein bacteriorhodopsin. Nature Structural Biology 2(2), 139-143.
-
(1995)
Nature Structural Biology
, vol.2
, Issue.2
, pp. 139-143
-
-
Booth, P.J.1
Flitsch, S.L.2
Stern, L.J.3
Greenhalgh, D.A.4
Kim, P.S.5
Khorana, H.G.6
-
14
-
-
28444488355
-
Solving the membrane protein folding problem
-
BOWIE, J. (2005). Solving the membrane protein folding problem. Nature 438(7068), 581-589.
-
(2005)
Nature
, vol.438
, Issue.7068
, pp. 581-589
-
-
Bowie, J.1
-
15
-
-
79551683006
-
Membrane protein folding: How important are hydrogen bonds?
-
BOWIE, J. U. (2011). Membrane protein folding: How important are hydrogen bonds? Current Opinion in Structural Biology 21 (1), 42-49.
-
(2011)
Current Opinion in Structural Biology
, vol.21
, Issue.1
, pp. 42-49
-
-
Bowie, J.U.1
-
16
-
-
33846901901
-
Intermediates: Ubiquitous species on folding energy landscapes?
-
BROCKWELL, D. J. & RADFORD, S. E. (2007). Intermediates: Ubiquitous species on folding energy landscapes?. Current Opinion in Structural Biology 17(1), 30-37.
-
(2007)
Current Opinion in Structural Biology
, vol.17
, Issue.1
, pp. 30-37
-
-
Brockwell, D.J.1
Radford, S.E.2
-
17
-
-
84870907436
-
Cleaning up: ER-Associated degradation to the rescue
-
BRODSKY, J. L. (2012). Cleaning up: ER-Associated degradation to the rescue. Cell 151(6), 1163-1167.
-
(2012)
Cell
, vol.151
, Issue.6
, pp. 1163-1167
-
-
Brodsky, J.L.1
-
18
-
-
79960711299
-
Protein folding and quality control in the endoplasmic reticulum: Recent lessons from yeast and mammalian cell systems
-
BRODSKY, J.L. & SKACH, W. R. (2011). Protein folding and quality control in the endoplasmic reticulum: Recent lessons from yeast and mammalian cell systems. Current Opinion in Cell Biology 23(4), 464-475.
-
(2011)
Current Opinion in Cell Biology
, vol.23
, Issue.4
, pp. 464-475
-
-
Brodsky, J.L.1
Skach, W.R.2
-
19
-
-
0030896451
-
Correcting temperature-sensitive protein folding defects
-
BROWN, C. R., HONG-BROWN, L.Q. & WELCH, W. J. (1997). Correcting temperature-sensitive protein folding defects. Journal of Clinical Investigation 99(6), 1432-1444.
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.6
, pp. 1432-1444
-
-
Brown, C.R.1
Hong-Brown, L.Q.2
Welch, W.J.3
-
20
-
-
84870901092
-
Curvature forces in membrane lipid-protein interactions
-
BROWN, M. F. (2012). Curvature forces in membrane lipid-protein interactions. Biochemistry 51(49), 9782-9795.
-
(2012)
Biochemistry
, vol.51
, Issue.49
, pp. 9782-9795
-
-
Brown, M.F.1
-
21
-
-
78649357985
-
Protein quality control in the cytosol and the endoplasmic reticulum: Brothers in arms
-
BUCHBERGER, A., BUKAU, B. & SOMMER, T. (2010). Protein quality control in the cytosol and the endoplasmic reticulum: Brothers in arms. Molecular Cell 40(2), 238-252.
-
(2010)
Molecular Cell
, vol.40
, Issue.2
, pp. 238-252
-
-
Buchberger, A.1
Bukau, B.2
Sommer, T.3
-
22
-
-
12844283314
-
Differential stability of biogenesis intermediates reveals a common pathway for aquaporin-1 topological maturation
-
BUCK, T.M. & SKACH, W. R. (2005). Differential stability of biogenesis intermediates reveals a common pathway for aquaporin-1 topological maturation. Journal of Biological Chemistry 280(1), 261-269.
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.1
, pp. 261-269
-
-
Buck, T.M.1
Skach, W.R.2
-
23
-
-
55549120907
-
Beta-barrel proteins that reside in the Escherichia coli outer membrane in vivo demonstrate varied folding behavior in vitro
-
BURGESS, N., DAO, T., STANLEY, A. & FLEMING, K. (2008). Beta-barrel proteins that reside in the Escherichia coli outer membrane in vivo demonstrate varied folding behavior in vitro. Journal of Biological Chemistry 283(39), 26748-26758.
-
(2008)
Journal of Biological Chemistry
, vol.283
, Issue.39
, pp. 26748-26758
-
-
Burgess, N.1
Dao, T.2
Stanley, A.3
Fleming, K.4
-
24
-
-
84856089134
-
Small-molecule proteostasis regulators for protein conformational diseases
-
CALAMINI, B., SILVA, M. C., MADOUX, F., HUTT, D. M., KHANNA, S., CHALFANT, M. A., SALDANHA, S. A., HODDER, P., TAIT, B. D., GARZA, D., BALCH, W.E. & MORIMOTO, R. I. (2012). Small-molecule proteostasis regulators for protein conformational diseases. Nature Chemical Biology 8(2), 185-196.
-
(2012)
Nature Chemical Biology
, vol.8
, Issue.2
, pp. 185-196
-
-
Calamini, B.1
Silva, M.C.2
Madoux, F.3
Hutt, D.M.4
Khanna, S.5
Chalfant, M.A.6
Saldanha, S.A.7
Hodder, P.8
Tait, B.D.9
Garza, D.10
Balch, W.E.11
Morimoto, R.I.12
-
25
-
-
0035872923
-
Quality control of transmembrane domain assembly in the tetraspanin CD82
-
CANNON, K.S. & CRESSWELL, P. (2001). Quality control of transmembrane domain assembly in the tetraspanin CD82. EMBO Journal 20(10), 2443-2453.
-
(2001)
EMBO Journal
, vol.20
, Issue.10
, pp. 2443-2453
-
-
Cannon, K.S.1
Cresswell, P.2
-
27
-
-
84857650575
-
Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state
-
CAO, Z., SCHLEBACH, J., PARK, C. & BOWIE, J. U. (2011). Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state. Biochimica et Biophysica Acta 1818(4), 1049-1054.
-
(2011)
Biochimica et Biophysica Acta
, vol.1818
, Issue.4
, pp. 1049-1054
-
-
Cao, Z.1
Schlebach, J.2
Park, C.3
Bowie, J.U.4
-
28
-
-
84868012854
-
Correction of F508del-CFTR trafficking by the sponge alkaloid latonduine is modulated by interaction with PARP
-
CARLILE, G.W., KEYZERS, R. A., TESKE, K. A., ROBERT, R., WILLIAMS, D. E., LININGTON, R. G., GRAY, C. A., CENTKO, R. M., YAN, L., ANJOS, S. M., SAMPSON, H. M., ZHANG, D., LIAO, J., HANRAHAN, J.W., ANDERSEN, R. J. & THOMAS, D. Y. (2012). Correction of F508del-CFTR trafficking by the sponge alkaloid latonduine is modulated by interaction with PARP. Chemical Biology 19(10), 1288-1299.
-
(2012)
Chemical Biology
, vol.19
, Issue.10
, pp. 1288-1299
-
-
Carlile, G.W.1
Keyzers, R.A.2
Teske, K.A.3
Robert, R.4
Williams, D.E.5
Linington, R.G.6
Gray, C.A.7
Centko, R.M.8
Yan, L.9
Anjos, S.M.10
Sampson, H.M.11
Zhang, D.12
Liao, J.13
Hanrahan, J.W.14
Andersen, R.J.15
Thomas, D.Y.16
-
29
-
-
84886391619
-
Nonfunctional NaV1 1 familial hemiplegic migraine mutant transformed into gain of function by partial rescue of folding defects
-
CESTÈLE, S., SCHIAVON, E., RUSCONI, R., FRANCESCHETTI, S. & MANTEGAZZA, M. (2013). Nonfunctional NaV1 1 familial hemiplegic migraine mutant transformed into gain of function by partial rescue of folding defects. Proceedings of the National Academy of Sciences of the United States of America 110(43), 17546-17551.
-
(2013)
Proceedings of the National Academy of Sciences of the United States of America
, vol.110
, Issue.43
, pp. 17546-17551
-
-
Cestèle, S.1
Schiavon, E.2
Rusconi, R.3
Franceschetti, S.4
Mantegazza, M.5
-
31
-
-
79958122250
-
The A391E mutation enhances FGFR3 activation in the absence of ligand
-
CHEN, F., DEGNIN, C., LAEDERICH, M., HORTON, W.A. & HRISTOVA, K. (2011). The A391E mutation enhances FGFR3 activation in the absence of ligand. Biochimica et Biophysica Acta 1808(8), 2045-2050.
-
(2011)
Biochimica et Biophysica Acta
, vol.1808
, Issue.8
, pp. 2045-2050
-
-
Chen, F.1
Degnin, C.2
Laederich, M.3
Horton, W.A.4
Hristova, K.5
-
32
-
-
0033609038
-
Topogenesis of cystic fibrosis transmembrane conductance regulator (CFTR): Regulation by the amino terminal transmembrane sequences
-
CHEN, M. & ZHANG, J. T. (1999). Topogenesis of cystic fibrosis transmembrane conductance regulator (CFTR): Regulation by the amino terminal transmembrane sequences. Biochemistry 38(17), 5471-5477.
-
(1999)
Biochemistry
, vol.38
, Issue.17
, pp. 5471-5477
-
-
Chen, M.1
Zhang, J.T.2
-
33
-
-
0025242929
-
Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis
-
CHENG, S. H., GREGORY, R. J., MARSHALL, J., PAUL, S., SOUZA, D.W., WHITE, G. A., O'RIORDAN, C.R. & SMITH, A.E. (1990). Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis. Cell 63(4), 827-834.
-
(1990)
Cell
, vol.63
, Issue.4
, pp. 827-834
-
-
Cheng, S.H.1
Gregory, R.J.2
Marshall, J.3
Paul, S.4
Souza, D.W.5
White, G.A.6
O'Riordan, C.R.7
Smith, A.E.8
-
34
-
-
0346727128
-
Therapeutic approaches to protein-misfolding diseases
-
COHEN, F.E. & KELLY, J.W. (2003). Therapeutic approaches to protein-misfolding diseases. Nature 426(6968), 905-909.
-
(2003)
Nature
, vol.426
, Issue.6968
, pp. 905-909
-
-
Cohen, F.E.1
Kelly, J.W.2
-
35
-
-
84861653381
-
A chaperone trap contributes to the onset of cystic fibrosis
-
COPPINGER, J. A., HUTT, D. M., RAZVI, A., KOULOV, A. V., PANKOW, S., YATES, J. R. III & BALCH, W. E. (2012). A chaperone trap contributes to the onset of cystic fibrosis. PLoS ONE 7(5), e37682.
-
(2012)
PLoS ONE
, vol.7
, Issue.5
, pp. e37682
-
-
Coppinger, J.A.1
Hutt, D.M.2
Razvi, A.3
Koulov, A.V.4
Pankow, S.5
Yates, J.R.6
Balch, W.E.7
-
38
-
-
77957922696
-
The contribution of a covalently bound cofactor to the folding and thermodynamic stability of an integral membrane protein
-
CURNOW, P. & BOOTH, P. J. (2010). The contribution of a covalently bound cofactor to the folding and thermodynamic stability of an integral membrane protein. Journal of Molecular Biology 403(4), 630-642.
-
(2010)
Journal of Molecular Biology
, vol.403
, Issue.4
, pp. 630-642
-
-
Curnow, P.1
Booth, P.J.2
-
39
-
-
80052144339
-
Stable folding core in the folding transition state of an alpha-helical integral membrane protein
-
CURNOW, P., DI BARTOLO, N. D., MORETON, K. M., AJOJE, O. O., SAGGESE, N.P. & BOOTH, P. J. (2011). Stable folding core in the folding transition state of an alpha-helical integral membrane protein. Proceedings of the National Academy of Sciences of the United States of America 108(34), 14133-14138.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.34
, pp. 14133-14138
-
-
Curnow, P.1
Bartolo N D, D.I.2
Moreton, K.M.3
Ajoje, O.O.4
Saggese, N.P.5
Booth, P.J.6
-
41
-
-
84896799648
-
Folding of synthetic homogeneous glycoproteins in the presence of a glycoprotein folding sensor enzyme
-
DEDOLA, S., IZUMI, M., MAKIMURA, Y., SEKO, A., KANAMORI, A., SAKONO, M., ITO, Y. & KAJIHARA, Y. (2014). Folding of synthetic homogeneous glycoproteins in the presence of a glycoprotein folding sensor enzyme. Angewandte Chemie International Edition English 53(11), 2883-2887.
-
(2014)
Angewandte Chemie International Edition English
, vol.53
, Issue.11
, pp. 2883-2887
-
-
Dedola, S.1
Izumi, M.2
Makimura, Y.3
Seko, A.4
Kanamori, A.5
Sakono, M.6
Ito, Y.7
Kajihara, Y.8
-
42
-
-
84899424468
-
The Sec translocon mediated protein transport in prokaryotes and eukaryotes
-
DENKS, K., VOGT, A., SACHELARU, I., PETRIMAN, N. A., KUDVA, R. & KOCH, H. G. (2014). The Sec translocon mediated protein transport in prokaryotes and eukaryotes. Molecular Membrane Biology 31(2-3), 58-84.
-
(2014)
Molecular Membrane Biology
, vol.31
, Issue.2-3
, pp. 58-84
-
-
Denks, K.1
Vogt, A.2
Sachelaru, I.3
Petriman, N.A.4
Kudva, R.5
Koch, H.G.6
-
43
-
-
0026781952
-
Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive
-
DENNING, G. M., ANDERSON, M. P., AMARA, J. F., MARSHALL, J., SMITH, A.E. &WELSH, M. J. (1992). Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive. Nature 358(6389), 761-764.
-
(1992)
Nature
, vol.358
, Issue.6389
, pp. 761-764
-
-
Denning, G.M.1
Anderson, M.P.2
Amara, J.F.3
Marshall, J.4
Smith, A.E.5
Welsh, M.J.6
-
44
-
-
79959961077
-
Stepwise insertion and inversion of a type II signal anchor sequence in the ribosome-Sec61 translocon complex
-
DEVARANENI, P. K., CONTI, B., MATSUMURA, Y., YANG, Z., JOHNSON, A.E. & SKACH, W. R. (2011). Stepwise insertion and inversion of a type II signal anchor sequence in the ribosome-Sec61 translocon complex. Cell 146(1), 134-147.
-
(2011)
Cell
, vol.146
, Issue.1
, pp. 134-147
-
-
Devaraneni, P.K.1
Conti, B.2
Matsumura, Y.3
Yang, Z.4
Johnson, A.E.5
Skach, W.R.6
-
45
-
-
36749104299
-
A common mechanism of PLP/DM20 misfolding causes cysteine-mediated endoplasmic reticulum retention in oligodendrocytes and Pelizaeus-Merzbacher disease
-
DHAUNCHAK, A.S. & NAVE, K. A. (2007). A common mechanism of PLP/DM20 misfolding causes cysteine-mediated endoplasmic reticulum retention in oligodendrocytes and Pelizaeus-Merzbacher disease. Proceedings of the National Academy of Sciences of the United States of America 104(45), 17813-17818.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.45
, pp. 17813-17818
-
-
Dhaunchak, A.S.1
Nave, K.A.2
-
46
-
-
84869761071
-
The protein-folding problem, 50 years on
-
DILL, K.A. & MACCALLUM, J. L. (2012). The protein-folding problem, 50 years on. Science 338(6110), 1042-1046.
-
(2012)
Science
, vol.338
, Issue.6110
, pp. 1042-1046
-
-
Dill, K.A.1
MacCallum, J.L.2
-
47
-
-
81055141521
-
Physical limits of cells and proteomes
-
DILL, K. A., GHOSH, K. & SCHMIT, J. D. (2011). Physical limits of cells and proteomes. Proceedings of the National Academy of Sciences of the United States of America 108(44), 17876-17882.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.44
, pp. 17876-17882
-
-
Dill, K.A.1
Ghosh, K.2
Schmit, J.D.3
-
48
-
-
3843102625
-
Sequence context modulates the stability of a GxxxG-mediated transmembrane helix-helix dimer
-
DOURA, A. K., KOBUS, F. J., DUBROVSKY, L., HIBBARD, E. & FLEMING, K. G. (2004). Sequence context modulates the stability of a GxxxG-mediated transmembrane helix-helix dimer. Journal of Molecular Biology 341(4), 991-998.
-
(2004)
Journal of Molecular Biology
, vol.341
, Issue.4
, pp. 991-998
-
-
Doura, A.K.1
Kobus, F.J.2
Dubrovsky, L.3
Hibbard, E.4
Fleming, K.G.5
-
49
-
-
77955018405
-
Characterization of membrane protein non-native states 2 the SDS-unfolded states of rhodopsin
-
DUTTA, A., KIM, T. Y., MOELLER, M., WU, J., ALEXIEV, U. & KLEIN-SEETHARAMAN, J. (2010). Characterization of membrane protein non-native states. 2. The SDS-unfolded states of rhodopsin. Biochemistry 49(30), 6329-6340.
-
(2010)
Biochemistry
, vol.49
, Issue.30
, pp. 6329-6340
-
-
Dutta, A.1
Kim, T.Y.2
Moeller, M.3
Wu, J.4
Alexiev, U.5
Klein-Seetharaman, J.6
-
50
-
-
84901398808
-
VX-809 and related corrector compounds exhibit secondary activity stabilizing active F508del-CFTR after its partial rescue to the cell surface
-
ECKFORD, P. D., RAMJEESINGH, M., MOLINSKI, S., PASYK, S., DEKKERS, J. F., LI, C., AHMADI, S., IP, W., CHUNG, T. E., DU, K., YEGER, H., BEEKMAN, J., GONSKA, T. & BEAR, C. E. (2014). VX-809 and related corrector compounds exhibit secondary activity stabilizing active F508del-CFTR after its partial rescue to the cell surface. Chemical Biology, 21(5), 666-678.
-
(2014)
Chemical Biology
, vol.21
, Issue.5
, pp. 666-678
-
-
Eckford, P.D.1
Ramjeesingh, M.2
Molinski, S.3
Pasyk, S.4
Dekkers, J.F.5
Li, C.6
Ahmadi, S.7
Ip, W.8
Chung, T.E.9
Du, K.10
Yeger, H.11
Beekman, J.12
Gonska, T.13
Bear, C.E.14
-
52
-
-
84872194587
-
Limitation of individual folding resources in the ER leads to outcomes distinct from the unfolded protein response
-
ELETTO, D., MAGANTY, A., ELETTO, D., DERSH, D., MAKAREWICH, C., BISWAS, C., PATON, J. C., PATON, A.W., DOROUDGAR, S., GLEMBOTSKI, C.C. & ARGON, Y. (2012). Limitation of individual folding resources in the ER leads to outcomes distinct from the unfolded protein response. Journal of Cell Science 125(Pt 20), 4865-4875.
-
(2012)
Journal of Cell Science
, vol.125
, pp. 4865-4875
-
-
Eletto, D.1
Maganty, A.2
Eletto, D.3
Dersh, D.4
Makarewich, C.5
Biswas, C.6
Paton, J.C.7
Paton, A.W.8
Doroudgar, S.9
Glembotski, C.C.10
Argon, Y.11
-
54
-
-
0019464222
-
The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis
-
ENGELMAN, D.M. & STEITZ, T. A. (1981). The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis. Cell 23(2), 411-422.
-
(1981)
Cell
, vol.23
, Issue.2
, pp. 411-422
-
-
Engelman, D.M.1
Steitz, T.A.2
-
55
-
-
0242657348
-
Membrane protein folding: Beyond the two stage model
-
ENGELMAN, D. M., CHEN, Y., CHIN, C. N., CURRAN, A. R., DIXON, A. M., DUPUY, A. D., LEE, A. S., LEHNERT, U., MATTHEWS, E. E., RESHETNYAK, Y. K., SENES, A. & POPOT, J. L. (2003). Membrane protein folding: Beyond the two stage model. FEBS Letters 555(1), 122-125.
-
(2003)
FEBS Letters
, vol.555
, Issue.1
, pp. 122-125
-
-
Engelman, D.M.1
Chen, Y.2
Chin, C.N.3
Curran, A.R.4
Dixon, A.M.5
Dupuy, A.D.6
Lee, A.S.7
Lehnert, U.8
Matthews, E.E.9
Reshetnyak, Y.K.10
Senes, A.11
Popot, J.L.12
-
56
-
-
84885095437
-
Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness during stress
-
ESCUSA-TORET, S., VONK, W. I. & FRYDMAN, J. (2013). Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness during stress. Nature Cellular Biology 15(10), 1231-1243.
-
(2013)
Nature Cellular Biology
, vol.15
, Issue.10
, pp. 1231-1243
-
-
Escusa-Toret, S.1
Vonk, W.I.2
Frydman, J.3
-
57
-
-
0344687314
-
Side-chain contributions to membrane protein structure and stability
-
FAHAM, S., YANG, D., BARE, E., YOHANNAN, S., WHITELEGGE, J. & BOWIE, J. (2004). Side-chain contributions to membrane protein structure and stability. Journal of Molecular Biology 335(1), 297-305.
-
(2004)
Journal of Molecular Biology
, vol.335
, Issue.1
, pp. 297-305
-
-
Faham, S.1
Yang, D.2
Bare, E.3
Yohannan, S.4
Whitelegge, J.5
Bowie, J.6
-
58
-
-
0033018496
-
Accelerated transport and maturation of lysosomal alphagalactosidase A in Fabry lymphoblasts by an enzyme inhibitor
-
FAN, J. Q., ISHII, S., ASANO, N. & SUZUKI, Y. (1999). Accelerated transport and maturation of lysosomal alphagalactosidase A in Fabry lymphoblasts by an enzyme inhibitor. Nature Medicine 5(1), 112-115.
-
(1999)
Nature Medicine
, vol.5
, Issue.1
, pp. 112-115
-
-
Fan, J.Q.1
Ishii, S.2
Asano, N.3
Suzuki, Y.4
-
59
-
-
84883465161
-
Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: Not just from the endoplasmic reticulum to the Golgi
-
FARINHA, C. M., MATOS, P. & AMARAL, M. D. (2013). Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: Not just from the endoplasmic reticulum to the Golgi. FEBS Journal 280(18), 4396-4406.
-
(2013)
FEBS Journal
, vol.280
, Issue.18
, pp. 4396-4406
-
-
Farinha, C.M.1
Matos, P.2
Amaral, M.D.3
-
60
-
-
84881536447
-
Quality control of integral membrane proteins by assembly-dependent membrane integration
-
FEIGE, M. J. & HENDERSHOT, L.M. (2013). Quality control of integral membrane proteins by assembly-dependent membrane integration. Molecular Cell 51(3), 297-309.
-
(2013)
Molecular Cell
, vol.51
, Issue.3
, pp. 297-309
-
-
Feige, M.J.1
Hendershot, L.M.2
-
61
-
-
0037085464
-
The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-A-gogo-related gene (HERG) mutations
-
FICKER, E., OBEJERO-PAZ, C. A., ZHAO, S. & BROWN, A.M. (2002). The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-A-gogo-related gene (HERG) mutations. Journal of Biological Chemistry 277(7), 4989-4998.
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.7
, pp. 4989-4998
-
-
Ficker, E.1
Obejero-Paz, C.A.2
Zhao, S.3
Brown, A.M.4
-
62
-
-
78649878713
-
Unfolding free energy of a two-domain transmembrane sugar transport protein
-
FINDLAY, H. E., RUTHERFORD, N. G., HENDERSON, P. J. & BOOTH, P. J. (2010). Unfolding free energy of a two-domain transmembrane sugar transport protein. Proceedings of the National Academy of Sciences of the United States of America 107 (43), 18451-18456.
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, Issue.43
, pp. 18451-18456
-
-
Findlay, H.E.1
Rutherford, N.G.2
Henderson, P.J.3
Booth, P.J.4
-
63
-
-
0036408542
-
Standardizing the free energy change of transmembrane helix-helix interactions
-
FLEMING, K. G. (2002). Standardizing the free energy change of transmembrane helix-helix interactions. Journal of Molecular Biology 323(3), 563-571.
-
(2002)
Journal of Molecular Biology
, vol.323
, Issue.3
, pp. 563-571
-
-
Fleming, K.G.1
-
64
-
-
84901986762
-
Energetics of membrane protein folding
-
FLEMING, K.G. (2014). Energetics of membrane protein folding. Annual Review of Biophysics 43, 233-255.
-
(2014)
Annual Review of Biophysics
, vol.43
, pp. 233-255
-
-
Fleming, K.G.1
-
66
-
-
0030777759
-
The effect of point mutations on the free energy of transmembrane alpha-helix dimerization
-
FLEMING, K. G., ACKERMAN, A.L. & ENGELMAN, D.M. (1997). The effect of point mutations on the free energy of transmembrane alpha-helix dimerization. Journal of Molecular Biolology 272(2), 266-275.
-
(1997)
Journal of Molecular Biolology
, vol.272
, Issue.2
, pp. 266-275
-
-
Fleming, K.G.1
Ackerman, A.L.2
Engelman, D.M.3
-
67
-
-
12544257563
-
Glycan-independent role of calnexin in the intracellular retention of Charcot-Marie-Tooth 1A Gas3/PMP22 mutants
-
FONTANINI, A., CHIES, R., SNAPP, E. L., FERRARINI, M., FABRIZI, G.M. & BRANCOLINI, C. (2005). Glycan-independent role of calnexin in the intracellular retention of Charcot-Marie-Tooth 1A Gas3/PMP22 mutants. Journal of Biological Chemistry 280(3), 2378-2387.
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.3
, pp. 2378-2387
-
-
Fontanini, A.1
Chies, R.2
Snapp, E.L.3
Ferrarini, M.4
Fabrizi, G.M.5
Brancolini, C.6
-
68
-
-
0344874551
-
Emerging role for autophagy in the removal of aggresomes in Schwann cells
-
FORTUN, J., DUNN, W. A., JOY, S., LI, J. & NOTTERPEK, L. (2003). Emerging role for autophagy in the removal of aggresomes in Schwann cells. Journal of Neuroscience 23(33), 10672-10680.
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.33
, pp. 10672-10680
-
-
Fortun, J.1
Dunn, W.A.2
Joy, S.3
Li, J.4
Notterpek, L.5
-
69
-
-
15244340084
-
Impaired proteasome activity and accumulation of ubiquitinated substrates in a hereditary neuropathy model
-
FORTUN, J., LI, J., GO, J., FENSTERMAKER, A., FLETCHER, B. S. & NOTTERPEK, L. (2005). Impaired proteasome activity and accumulation of ubiquitinated substrates in a hereditary neuropathy model. Journal of Neurochemistry 92(6), 1531-1541.
-
(2005)
Journal of Neurochemistry
, vol.92
, Issue.6
, pp. 1531-1541
-
-
Fortun, J.1
Li, J.2
Go, J.3
Fenstermaker, A.4
Fletcher, B.S.5
Notterpek, L.6
-
70
-
-
0028175016
-
Topological frustration in multispanning E. Coli inner membrane proteins
-
GAFVELIN, G. & VON HEIJNE, G. (1994). Topological 'frustration' in multispanning E. coli inner membrane proteins. Cell 77(3), 401-412.
-
(1994)
Cell
, vol.77
, Issue.3
, pp. 401-412
-
-
Gafvelin, G.1
Von Heijne, G.2
-
71
-
-
79551609332
-
BAG3 mediates chaperone-based aggresome-Targeting and selective autophagy of misfolded proteins
-
GAMERDINGER, M., KAYA, A. M., WOLFRUM, U., CLEMENT, A.M. & BEHL, C. (2011). BAG3 mediates chaperone-based aggresome-Targeting and selective autophagy of misfolded proteins. EMBO Reports 12(2), 149-156.
-
(2011)
EMBO Reports
, vol.12
, Issue.2
, pp. 149-156
-
-
Gamerdinger, M.1
Kaya, A.M.2
Wolfrum, U.3
Clement, A.M.4
Behl, C.5
-
72
-
-
0344466781
-
Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera
-
GARCIA-MATA, R., BEBOK, Z., SORSCHER, E. J. & SZTUL, E. S. (1999). Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera. Journal of Cell Biology 146(6), 1239-1254.
-
(1999)
Journal of Cell Biology
, vol.146
, Issue.6
, pp. 1239-1254
-
-
Garcia-Mata, R.1
Bebok, Z.2
Sorscher, E.J.3
Sztul, E.S.4
-
73
-
-
0036303981
-
Hassles with taking out the garbage: Aggravating aggresomes
-
GARCIA-MATA, R., GAO, Y. S. & SZTUL, E. (2002). Hassles with taking out the garbage: Aggravating aggresomes. Traffic 3(6), 388-396.
-
(2002)
Traffic
, vol.3
, Issue.6
, pp. 388-396
-
-
Garcia-Mata, R.1
Gao, Y.S.2
Sztul, E.3
-
74
-
-
84899126341
-
Outer membrane beta-barrel protein folding is physically controlled by periplasmic lipid head groups and BamA
-
GESSMANN, D., CHUNG, Y. H., DANOFF, E. J., PLUMMER, A. M., SANDLIN, C.W., ZACCAI, N.R. & FLEMING, K. G. (2014). Outer membrane beta-barrel protein folding is physically controlled by periplasmic lipid head groups and BamA. Proceedings of the National Academy of Sciences of the United States of America 111(16), 5878-5883.
-
(2014)
Proceedings of the National Academy of Sciences of the United States of America
, vol.111
, Issue.16
, pp. 5878-5883
-
-
Gessmann, D.1
Chung, Y.H.2
Danoff, E.J.3
Plummer, A.M.4
Sandlin, C.W.5
Zaccai, N.R.6
Fleming, K.G.7
-
75
-
-
84893329888
-
The back and forth of cargo exit from the endoplasmic reticulum
-
GEVA, Y. & SCHULDINER, M. (2014). The back and forth of cargo exit from the endoplasmic reticulum. Current Biology 24 (3), R130-R136.
-
(2014)
Current Biology
, vol.24
, Issue.3
, pp. R130-R136
-
-
Geva, Y.1
Schuldiner, M.2
-
77
-
-
78650217130
-
Cellular proteomes have broad distributions of protein stability
-
GHOSH, K. & DILL, K. (2010). Cellular proteomes have broad distributions of protein stability. Biophysical Journal 99(12), 3996-4002.
-
(2010)
Biophysical Journal
, vol.99
, Issue.12
, pp. 3996-4002
-
-
Ghosh, K.1
Dill, K.2
-
78
-
-
33644850056
-
Progressive disruption of cellular protein folding in models of polyglutamine diseases
-
GIDALEVITZ, T., BEN-ZVI, A., HO, K. H., BRIGNULL, H.R. & MORIMOTO, R. I. (2006). Progressive disruption of cellular protein folding in models of polyglutamine diseases. Science 311(5766), 1471-1474.
-
(2006)
Science
, vol.311
, Issue.5766
, pp. 1471-1474
-
-
Gidalevitz, T.1
Ben-Zvi, A.2
Ho, K.H.3
Brignull, H.R.4
Morimoto, R.I.5
-
79
-
-
77749319656
-
A cellular perspective on conformational disease: The role of genetic background and proteostasis networks
-
GIDALEVITZ, T., KIKIS, E.A. & MORIMOTO, R. I. (2010). A cellular perspective on conformational disease: The role of genetic background and proteostasis networks. Current Opinion in Structural Biology 20(1), 23-32.
-
(2010)
Current Opinion in Structural Biology
, vol.20
, Issue.1
, pp. 23-32
-
-
Gidalevitz, T.1
Kikis, E.A.2
Morimoto, R.I.3
-
80
-
-
0032512412
-
Cysteine residues of photoreceptor peripherin/rds: Role in subunit assembly and autosomal dominant retinitis pigmentosa
-
GOLDBERG, A. F., LOEWEN, C. J. & MOLDAY, R. S. (1998). Cysteine residues of photoreceptor peripherin/rds: Role in subunit assembly and autosomal dominant retinitis pigmentosa. Biochemistry 37(2), 680-685.
-
(1998)
Biochemistry
, vol.37
, Issue.2
, pp. 680-685
-
-
Goldberg, A.F.1
Loewen, C.J.2
Molday, R.S.3
-
81
-
-
33645211009
-
Mechanisms of pharmacological rescue of trafficking-defective hERG mutant channels in human long QT syndrome
-
GONG, Q., JONES, M.A. & ZHOU, Z. (2006). Mechanisms of pharmacological rescue of trafficking-defective hERG mutant channels in human long QT syndrome. Journal of Biological Chemistry 281(7), 4069-4074.
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.7
, pp. 4069-4074
-
-
Gong, Q.1
Jones, M.A.2
Zhou, Z.3
-
82
-
-
0035969998
-
Polar side chains drive the association of model transmembrane peptides
-
GRATKOWSKI, H., LEAR, J.D. & DEGRADO, W. F. (2001). Polar side chains drive the association of model transmembrane peptides. Proceedings of the National Academy of Sciences of the United States of America 98(3), 880-885.
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.3
, pp. 880-885
-
-
Gratkowski, H.1
Lear, J.D.2
Degrado, W.F.3
-
83
-
-
84897107417
-
Relative domain folding and stability of a membrane transport protein
-
HARRIS, N. J., FINDLAY, H. E., SIMMS, J., LIU, X. & BOOTH, P. J. (2014). Relative domain folding and stability of a membrane transport protein. Journal of Molecular Biology 426(8), 1812-1825.
-
(2014)
Journal of Molecular Biology
, vol.426
, Issue.8
, pp. 1812-1825
-
-
Harris, N.J.1
Findlay, H.E.2
Simms, J.3
Liu, X.4
Booth, P.J.5
-
84
-
-
56949102246
-
Pathogenic activation of receptor tyrosine kinases in mammalian membranes
-
HE, L. & HRISTOVA, K. (2008). Pathogenic activation of receptor tyrosine kinases in mammalian membranes. Journal of Molecular Biology 384(5), 1130-1142.
-
(2008)
Journal of Molecular Biology
, vol.384
, Issue.5
, pp. 1130-1142
-
-
He, L.1
Hristova, K.2
-
85
-
-
84866623060
-
Flagging and docking: Dual roles for N-glycans in protein quality control and cellular proteostasis
-
HEBERT, D.N. & MOLINARI, M. (2012). Flagging and docking: Dual roles for N-glycans in protein quality control and cellular proteostasis. Trends in Biochemical Sciences 37(10), 404-410.
-
(2012)
Trends in Biochemical Sciences
, vol.37
, Issue.10
, pp. 404-410
-
-
Hebert, D.N.1
Molinari, M.2
-
86
-
-
0042815085
-
Cooperation of transmembrane segments during the integration of a doublespanning protein into the ER membrane
-
HEINRICH, S.U. & RAPOPORT, T. A. (2003). Cooperation of transmembrane segments during the integration of a doublespanning protein into the ER membrane. EMBO Journal 22(14), 3654-3663.
-
(2003)
EMBO Journal
, vol.22
, Issue.14
, pp. 3654-3663
-
-
Heinrich, S.U.1
Rapoport, T.A.2
-
87
-
-
0034697967
-
The Sec61p complex mediates the integration of a membrane protein by allowing lipid partitioning of the transmembrane domain
-
HEINRICH, S. U., MOTHES, W., BRUNNER, J. & RAPOPORT, T. A. (2000). The Sec61p complex mediates the integration of a membrane protein by allowing lipid partitioning of the transmembrane domain. Cell 102(2), 233-244.
-
(2000)
Cell
, vol.102
, Issue.2
, pp. 233-244
-
-
Heinrich, S.U.1
Mothes, W.2
Brunner, J.3
Rapoport, T.A.4
-
88
-
-
0242551561
-
Inter-helical hydrogen bond formation during membrane protein integration into the ER membrane
-
HERMANSSON, M. & VON HEIJNE, G. (2003). Inter-helical hydrogen bond formation during membrane protein integration into the ER membrane. Journal of Molecular Biology 334(4), 803-809.
-
(2003)
Journal of Molecular Biology
, vol.334
, Issue.4
, pp. 803-809
-
-
Hermansson, M.1
Von Heijne, G.2
-
89
-
-
13444262028
-
Recognition of transmembrane helices by the endoplasmic reticulum translocon
-
HESSA, T., KIM, H., BIHLMAIER, K., LUNDIN, C., BOEKEL, J., ANDERSSON, H., NILSSON, I., WHITE, S.H. & VON HEIJNE, G. (2005). Recognition of transmembrane helices by the endoplasmic reticulum translocon. Nature 433(7024), 377-381.
-
(2005)
Nature
, vol.433
, Issue.7024
, pp. 377-381
-
-
Hessa, T.1
Kim, H.2
Bihlmaier, K.3
Lundin, C.4
Boekel, J.5
Andersson, H.6
Nilsson, I.7
White, S.H.8
Von Heijne, G.9
-
90
-
-
37249037182
-
Molecular code for transmembrane-helix recognition by the Sec61 translocon
-
HESSA, T., MEINDL-BEINKER, N. M., BERNSEL, A., KIM, H., SATO, Y., LERCH-BADER, M., NILSSON, I., WHITE, S.H. & VON HEIJNE, G. (2007). Molecular code for transmembrane-helix recognition by the Sec61 translocon. Nature 450(7172), 1026-1030.
-
(2007)
Nature
, vol.450
, Issue.7172
, pp. 1026-1030
-
-
Hessa, T.1
Meindl-Beinker, N.M.2
Bernsel, A.3
Kim, H.4
Sato, Y.5
Lerch-Bader, M.6
Nilsson, I.7
White, S.H.8
Von Heijne, G.9
-
91
-
-
79960590320
-
Dramatic destabilization of transmembrane helix interactions by features of natural membrane environments
-
HONG, H. & BOWIE, J. U. (2011). Dramatic destabilization of transmembrane helix interactions by features of natural membrane environments. Journal of the American Chemical Society 133(29), 11389-11398.
-
(2011)
Journal of the American Chemical Society
, vol.133
, Issue.29
, pp. 11389-11398
-
-
Hong, H.1
Bowie, J.U.2
-
93
-
-
61849083035
-
Methods for measuring the thermodynamic stability of membrane proteins
-
HONG, H., JOH, N., BOWIE, J. & TAMM, L. (2009). Methods for measuring the thermodynamic stability of membrane proteins. Methods in Enzymology 455, 213-236.
-
(2009)
Methods in Enzymology
, vol.455
, pp. 213-236
-
-
Hong, H.1
Joh, N.2
Bowie, J.3
Tamm, L.4
-
94
-
-
78650553544
-
Method to measure strong protein-protein interactions in lipid bilayers using a steric trap
-
HONG, H., BLOIS, T. M., CAO, Z. & BOWIE, J. U. (2010). Method to measure strong protein-protein interactions in lipid bilayers using a steric trap. Proceedings of the National Academy of Sciences of the United States of America 107(46), 19802-19807.
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, Issue.46
, pp. 19802-19807
-
-
Hong, H.1
Blois, T.M.2
Cao, Z.3
Bowie, J.U.4
-
95
-
-
84857648264
-
Mechanisms for quality control of misfolded transmembrane proteins
-
HOUCK, S.A. & CYR, D.M. (2012). Mechanisms for quality control of misfolded transmembrane proteins. Biochimica et Biophysica Acta 1818(4), 1108-1114.
-
(2012)
Biochimica et Biophysica Acta
, vol.1818
, Issue.4
, pp. 1108-1114
-
-
Houck, S.A.1
Cyr, D.M.2
-
96
-
-
0019887931
-
Refolding of an integral membrane protein. Denaturation, renaturation, and reconstitution of intact bacteriorhodopsin and two proteolytic fragments
-
HUANG, K. S., BAYLEY, H., LIAO, M. J., LONDON, E. & KHORANA, H. G. (1981). Refolding of an integral membrane protein. Denaturation, renaturation, and reconstitution of intact bacteriorhodopsin and two proteolytic fragments. Journal of Biological Chemistry 256(8), 3802-3809.
-
(1981)
Journal of Biological Chemistry
, vol.256
, Issue.8
, pp. 3802-3809
-
-
Huang, K.S.1
Bayley, H.2
Liao, M.J.3
London, E.4
Khorana, H.G.5
-
97
-
-
77749246164
-
The transition state for folding of an outer membrane protein
-
HUYSMANS, G. H., BALDWIN, S. A., BROCKWELL, D. J. & RADFORD, S. E. (2010). The transition state for folding of an outer membrane protein. Proceedings of the National Academy of Sciences of the United States of America 107(9), 4099-4104.
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, Issue.9
, pp. 4099-4104
-
-
Huysmans, G.H.1
Baldwin, S.A.2
Brockwell, D.J.3
Radford, S.E.4
-
98
-
-
84856710960
-
Malleability of the folding mechanism of the outer membrane protein PagP: Parallel pathways and the effect of membrane elasticity
-
HUYSMANS, G. H., RADFORD, S. E., BALDWIN, S.A. & BROCKWELL, D. J. (2012). Malleability of the folding mechanism of the outer membrane protein PagP: Parallel pathways and the effect of membrane elasticity. Journal of Molecular Biology 416 (3), 453-464.
-
(2012)
Journal of Molecular Biology
, vol.416
, Issue.3
, pp. 453-464
-
-
Huysmans, G.H.1
Radford, S.E.2
Baldwin, S.A.3
Brockwell, D.J.4
-
99
-
-
0033515036
-
Structure and function in rhodopsin: Further elucidation of the role of the intradiscal cysteines, Cys-110,-185, and-187, in rhodopsin folding and function
-
HWA, J., REEVES, P. J., KLEIN-SEETHARAMAN, J., DAVIDSON, F. & KHORANA, H. G. (1999). Structure and function in rhodopsin: Further elucidation of the role of the intradiscal cysteines, Cys-110,-185, and-187, in rhodopsin folding and function. Proceedings of the National Academy of Sciences of the United States of America 96(5), 1932-1935.
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.5
, pp. 1932-1935
-
-
Hwa, J.1
Reeves, P.J.2
Klein-Seetharaman, J.3
Davidson, F.4
Khorana, H.G.5
-
100
-
-
78649770531
-
Why are polar residues within the membrane core evolutionary conserved?
-
ILLERGARD, K., KAUKO, A. & ELOFSSON, A. (2011). Why are polar residues within the membrane core evolutionary conserved? Proteins 79(1), 79-91.
-
(2011)
Proteins
, vol.79
, Issue.1
, pp. 79-91
-
-
Illergard, K.1
Kauko, A.2
Elofsson, A.3
-
101
-
-
84891357083
-
Restoration of testis function in hypogonadotropic hypogonadal mice harboring a misfolded GnRHR mutant by pharmacoperone drug therapy
-
JANOVICK, J. A., STEWART, M. D., JACOB, D., MARTIN, L. D., DENG, J. M., STEWART, C. A., WANG, Y., CORNEA, A., CHAVALI, L., LOPEZ, S., MITALIPOV, S., KANG, E., LEE, H. S., MANNA, P. R., STOCCO, D. M., BEHRINGER, R.R. & CONN, P.M. (2013). Restoration of testis function in hypogonadotropic hypogonadal mice harboring a misfolded GnRHR mutant by pharmacoperone drug therapy. Proceedings of the National Academy of Sciences of the United States of America 110(52), 21030-21035.
-
(2013)
Proceedings of the National Academy of Sciences of the United States of America
, vol.110
, Issue.52
, pp. 21030-21035
-
-
Janovick, J.A.1
Stewart, M.D.2
Jacob, D.3
Martin, L.D.4
Deng, J.M.5
Stewart, C.A.6
Wang, Y.7
Cornea, A.8
Chavali, L.9
Lopez, S.10
Mitalipov, S.11
Kang, E.12
Lee, H.S.13
Manna, P.R.14
Stocco, D.M.15
Behringer, R.R.16
Conn, P.M.17
-
102
-
-
0037122769
-
Energetic landscape of alpha-lytic protease optimizes longevity through kinetic stability
-
JASWAL, S. S., SOHL, J. L., DAVIS, J.H. & AGARD, D. A. (2002). Energetic landscape of alpha-lytic protease optimizes longevity through kinetic stability. Nature 415(6869), 343-346.
-
(2002)
Nature
, vol.415
, Issue.6869
, pp. 343-346
-
-
Jaswal, S.S.1
Sohl, J.L.2
Davis, J.H.3
Agard, D.A.4
-
103
-
-
84885579356
-
Membrane proteins can have high kinetic stability
-
JEFFERSON, R. E., BLOIS, T.M. & BOWIE, J. U. (2013). Membrane proteins can have high kinetic stability. Journal of the American Chemical Society 135(40), 15183-15190.
-
(2013)
Journal of the American Chemical Society
, vol.135
, Issue.40
, pp. 15183-15190
-
-
Jefferson, R.E.1
Blois, T.M.2
Bowie, J.U.3
-
105
-
-
46249089993
-
Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins
-
JOH, N., MIN, A., FAHAM, S., WHITELEGGE, J., YANG, D., WOODS, V. & BOWIE, J. (2008). Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins. Nature 453(7199), 1266-1270.
-
(2008)
Nature
, vol.453
, Issue.7199
, pp. 1266-1270
-
-
Joh, N.1
Min, A.2
Faham, S.3
Whitelegge, J.4
Yang, D.5
Woods, V.6
Bowie, J.7
-
106
-
-
68249144241
-
Similar energetic contributions of packing in the core of membrane and water-soluble proteins
-
American Chemical Society
-
JOH, N. H., OBERAI, A., YANG, D., WHITELEGGE, J.P. & BOWIE, J. U. (2009). Similar energetic contributions of packing in the core of membrane and water-soluble proteins. Journal of the American Chemical Society 131(31), 10846-10847.
-
(2009)
Journal of the
, vol.131
, Issue.31
, pp. 10846-10847
-
-
Joh, N.H.1
Oberai, A.2
Yang, D.3
Whitelegge, J.P.4
Bowie, J.U.5
-
108
-
-
0032576605
-
Aggresomes: A cellular response to misfolded proteins
-
JOHNSTON, J. A., WARD, C.L. & KOPITO, R. R. (1998). Aggresomes: A cellular response to misfolded proteins. Journal of Cell Biology 143(7), 1883-1898.
-
(1998)
Journal of Cell Biology
, vol.143
, Issue.7
, pp. 1883-1898
-
-
Johnston, J.A.1
Ward, C.L.2
Kopito, R.R.3
-
109
-
-
0036733778
-
Cytoplasmic dynein/dynactin mediates the assembly of aggresomes
-
JOHNSTON, J. A., ILLING, M.E. & KOPITO, R. R. (2002). Cytoplasmic dynein/dynactin mediates the assembly of aggresomes. Cell Motility and the Cytoskeleton 53(1), 26-38.
-
(2002)
Cell Motility and the Cytoskeleton
, vol.53
, Issue.1
, pp. 26-38
-
-
Johnston, J.A.1
Illing, M.E.2
Kopito, R.R.3
-
110
-
-
80355148479
-
Specialization of endoplasmic reticulum chaperones for the folding and function of myelin glycoproteins P0 and PMP22
-
JUNG, J., COE, H. & MICHALAK, M. (2011). Specialization of endoplasmic reticulum chaperones for the folding and function of myelin glycoproteins P0 and PMP22. FASEB Journal 25(11), 3929-3937.
-
(2011)
FASEB Journal
, vol.25
, Issue.11
, pp. 3929-3937
-
-
Jung, J.1
Coe, H.2
Michalak, M.3
-
111
-
-
50649116818
-
Misfolded proteins partition between two distinct quality control compartments
-
KAGANOVICH, D., KOPITO, R. & FRYDMAN, J. (2008). Misfolded proteins partition between two distinct quality control compartments. Nature 454(7208), 1088-1095.
-
(2008)
Nature
, vol.454
, Issue.7208
, pp. 1088-1095
-
-
Kaganovich, D.1
Kopito, R.2
Frydman, J.3
-
112
-
-
77949351438
-
Modularity of the Hrd1 ERAD complex underlies its diverse client range
-
KANEHARA, K., XIE, W. & NG, D. T. (2010). Modularity of the Hrd1 ERAD complex underlies its diverse client range. Journal of Cell Biology 188(5), 707-716.
-
(2010)
Journal of Cell Biology
, vol.188
, Issue.5
, pp. 707-716
-
-
Kanehara, K.1
Xie, W.2
Ng, T.3
-
113
-
-
0037180396
-
The Tenth Membrane Region of Band 3 Is Initially Exposed to the Luminal Side of the Endoplasmic Reticulum and Then Integrated into A Partially Folded Band 3 Intermediate
-
KANKI, T., SAKAGUCHI, M., KITAMURA, A., SATO, T., MIHARA, K. & HAMASAKI, N. (2002). The tenth membrane region of band 3 is initially exposed to the luminal side of the endoplasmic reticulum and then integrated into a partially folded band 3 intermediate. Biochemistry 41(47), 13973-13981.
-
(2002)
Biochemistry
, vol.41
, Issue.47
, pp. 13973-13981
-
-
Kanki, T.1
Sakaguchi, M.2
Kitamura, A.3
Sato, T.4
Mihara, K.5
Hamasaki, N.6
-
114
-
-
0037129978
-
The amino terminus of opsin translocates posttranslationally as efficiently as cotranslationally
-
KANNER, E. M., KLEIN, I. K., FRIEDLANDER, M. & SIMON, S.M. (2002). The amino terminus of opsin translocates 'posttranslationally' as efficiently as cotranslationally. Biochemistry 41(24), 7707-7715.
-
(2002)
Biochemistry
, vol.41
, Issue.24
, pp. 7707-7715
-
-
Kanner, E.M.1
Klein, I.K.2
Friedlander, M.3
Simon, S.M.4
-
115
-
-
77249173166
-
Repositioning of transmembrane alpha-helices during membrane protein folding
-
KAUKO, A., HEDIN, L. E., THEBAUD, E., CRISTOBAL, S., ELOFSSON, A. & VON HEIJNE, G. (2010). Repositioning of transmembrane alpha-helices during membrane protein folding. Journal of Molecular Biology 397(1), 190-201.
-
(2010)
Journal of Molecular Biology
, vol.397
, Issue.1
, pp. 190-201
-
-
Kauko, A.1
Hedin, L.E.2
Thebaud, E.3
Cristobal, S.4
Elofsson, A.5
Von Heijne, G.6
-
116
-
-
0028287273
-
Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa
-
KAUSHAL, S. & KHORANA, H. G. (1994). Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa. Biochemistry 33(20), 6121-6128.
-
(1994)
Biochemistry
, vol.33
, Issue.20
, pp. 6121-6128
-
-
Kaushal, S.1
Khorana, H.G.2
-
117
-
-
0346020435
-
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
-
KAWAGUCHI, Y., KOVACS, J. J., MCLAURIN, A., VANCE, J. M., ITO, A. & YAO, T. P. (2003). The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress. Cell 115(6), 727-738.
-
(2003)
Cell
, vol.115
, Issue.6
, pp. 727-738
-
-
Kawaguchi, Y.1
Kovacs, J.J.2
McLaurin, A.3
Vance, J.M.4
Ito, A.5
Yao, T.P.6
-
118
-
-
33646447690
-
The integration of cell and chemical biology in protein folding
-
KELLY, J.W. & BALCH, W. E. (2006). The integration of cell and chemical biology in protein folding. Nature Chemical Biology 2(5), 224-227.
-
(2006)
Nature Chemical Biology
, vol.2
, Issue.5
, pp. 224-227
-
-
Kelly, J.W.1
Balch, W.E.2
-
119
-
-
79952653259
-
Ligand-driven vectorial folding of ribosome-bound human CFTR NBD1
-
KHUSHOO, A., YANG, Z., JOHNSON, A.E. & SKACH, W. R. (2011). Ligand-driven vectorial folding of ribosome-bound human CFTR NBD1. Molecular Cell 41(6), 682-692.
-
(2011)
Molecular Cell
, vol.41
, Issue.6
, pp. 682-692
-
-
Khushoo, A.1
Yang, Z.2
Johnson, A.E.3
Skach, W.R.4
-
120
-
-
84904968329
-
Predictive energy landscapes for folding alpha-helical transmembrane proteins
-
KIM, B. L., SCHAFER, N.P. & WOLYNES, P. G. (2014). Predictive energy landscapes for folding alpha-helical transmembrane proteins. Proceedings of the National Academy of Sciences of the United States of America 111(30), 11031-11036.
-
(2014)
Proceedings of the National Academy of Sciences of the United States of America
, vol.111
, Issue.30
, pp. 11031-11036
-
-
Kim, B.L.1
Schafer, N.P.2
Wolynes, P.G.3
-
121
-
-
84879417365
-
Mechanisms of CFTR folding at the endoplasmic reticulum
-
KIM, S. J. & SKACH, W. R. (2012). Mechanisms of CFTR folding at the endoplasmic reticulum. Frontiers in Pharmacology 3, 201.
-
(2012)
Frontiers in Pharmacology
, vol.3
, pp. 201
-
-
Kim, S.J.1
Skach, W.R.2
-
122
-
-
0034578389
-
Aggresomes, inclusion bodies and protein aggregation
-
KOPITO, R. R. (2000). Aggresomes, inclusion bodies and protein aggregation. Trends in Cell Biology 10(12), 524-530.
-
(2000)
Trends in Cell Biology
, vol.10
, Issue.12
, pp. 524-530
-
-
Kopito, R.R.1
-
123
-
-
0032584722
-
Protein folding stability can determine the efficiency of escape from endoplasmic reticulum quality control
-
KOWALSKI, J. M., PAREKH, R. N., MAO, J. & WITTRUP, K. D. (1998). Protein folding stability can determine the efficiency of escape from endoplasmic reticulum quality control. Journal of Biological Chemistry 273(31), 19453-19458.
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.31
, pp. 19453-19458
-
-
Kowalski, J.M.1
Parekh, R.N.2
Mao, J.3
Wittrup, K.D.4
-
124
-
-
0032477891
-
Secretion efficiency in Saccharomyces cerevisiae of bovine pancreatic trypsin inhibitor mutants lacking disulfide bonds is correlated with thermodynamic stability
-
KOWALSKI, J. M., PAREKH, R.N. & WITTRUP, K. D. (1998). Secretion efficiency in Saccharomyces cerevisiae of bovine pancreatic trypsin inhibitor mutants lacking disulfide bonds is correlated with thermodynamic stability. Biochemistry 37(5), 1264-1273.
-
(1998)
Biochemistry
, vol.37
, Issue.5
, pp. 1264-1273
-
-
Kowalski, J.M.1
Parekh, R.N.2
Wittrup, K.D.3
-
125
-
-
79953837301
-
Structural changes in bacteriorhodopsin during in vitro refolding from a partially denatured state
-
KRISHNAMANI, V. & LANYI, J. K. (2011). Structural changes in bacteriorhodopsin during in vitro refolding from a partially denatured state. Biophysical Journal 100(6), 1559-1567.
-
(2011)
Biophysical Journal
, vol.100
, Issue.6
, pp. 1559-1567
-
-
Krishnamani, V.1
Lanyi, J.K.2
-
126
-
-
84856853534
-
Secondary and tertiary structure of bacteriorhodopsin in the SDS denatured state
-
KRISHNAMANI, V., HEGDE, B. G., LANGEN, R. & LANYI, J. K. (2012). Secondary and tertiary structure of bacteriorhodopsin in the SDS denatured state. Biochemistry 51(6), 1051-1060.
-
(2012)
Biochemistry
, vol.51
, Issue.6
, pp. 1051-1060
-
-
Krishnamani, V.1
Hegde, B.G.2
Langen, R.3
Lanyi, J.K.4
-
127
-
-
0031010621
-
A method for assessing the stability of a membrane protein
-
LAU, F. & BOWIE, J. (1997). A method for assessing the stability of a membrane protein. Biochemistry 36(19), 5884-5892.
-
(1997)
Biochemistry
, vol.36
, Issue.19
, pp. 5884-5892
-
-
Lau, F.1
Bowie, J.2
-
128
-
-
8444242974
-
Bi-directional protein transport between the ER and Golgi
-
LEE, M. C., MILLER, E. A., GOLDBERG, J., ORCI, L. & SCHEKMAN, R. (2004). Bi-directional protein transport between the ER and Golgi. Annual Review of Cell and Developmental Biology 20, 87-123.
-
(2004)
Annual Review of Cell and Developmental Biology
, vol.20
, pp. 87-123
-
-
Lee, M.C.1
Miller, E.A.2
Goldberg, J.3
Orci, L.4
Schekman, R.5
-
129
-
-
31344468061
-
FGFR3 dimer stabilization due to a single amino acid pathogenic mutation
-
LI, E., YOU, M. & HRISTOVA, K. (2006). FGFR3 dimer stabilization due to a single amino acid pathogenic mutation. Journal of Molecular Biology 356(3), 600-612.
-
(2006)
Journal of Molecular Biology
, vol.356
, Issue.3
, pp. 600-612
-
-
Li, E.1
You, M.2
Hristova, K.3
-
130
-
-
84855465724
-
Transmembrane helix dimerization: Beyond the search for sequence motifs
-
LI, E., WIMLEY, W.C. & HRISTOVA, K. (2012). Transmembrane helix dimerization: Beyond the search for sequence motifs. Biochimica et Biophysica Acta 1818(2), 183-193.
-
(2012)
Biochimica et Biophysica Acta
, vol.1818
, Issue.2
, pp. 183-193
-
-
Li, E.1
Wimley, W.C.2
Hristova, K.3
-
131
-
-
84883137706
-
The PMP22 gene and its related diseases
-
LI, J., PARKER, B., MARTYN, C., NATARAJAN, C. & GUO, J. (2012). The PMP22 gene and its related diseases. Molecular Neurobiology 47(2), 673-698.
-
(2012)
Molecular Neurobiology
, vol.47
, Issue.2
, pp. 673-698
-
-
Li, J.1
Parker, B.2
Martyn, C.3
Natarajan, C.4
Guo, J.5
-
132
-
-
0029943263
-
Structure and function in rhodopsin: Correct folding and misfolding in two point mutants in the intradiscal domain of rhodopsin identified in retinitis pigmentosa
-
LIU, X., GARRIGA, P. & KHORANA, H. G. (1996). Structure and function in rhodopsin: Correct folding and misfolding in two point mutants in the intradiscal domain of rhodopsin identified in retinitis pigmentosa. Proceedings of the National Academy of Sciences of the United States of America 93(10), 4554-4559.
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.10
, pp. 4554-4559
-
-
Liu, X.1
Garriga, P.2
Khorana, H.G.3
-
133
-
-
0020490831
-
Denaturation and renaturation of bacteriorhodopsin in detergents and lipid-detergent mixtures
-
LONDON, E. & KHORANA, H. (1982). Denaturation and renaturation of bacteriorhodopsin in detergents and lipid-detergent mixtures. Journal of Biological Chemistry 257(12), 7003-7011.
-
(1982)
Journal of Biological Chemistry
, vol.257
, Issue.12
, pp. 7003-7011
-
-
London, E.1
Khorana, H.2
-
134
-
-
0034716941
-
The final stages of folding of the membrane protein bacteriorhodopsin occur by kinetically indistinguishable parallel folding paths that are mediated by pH
-
LU, H. & BOOTH, P. J. (2000). The final stages of folding of the membrane protein bacteriorhodopsin occur by kinetically indistinguishable parallel folding paths that are mediated by pH. Journal of Molecular Biology 299(1), 233-243.
-
(2000)
Journal of Molecular Biology
, vol.299
, Issue.1
, pp. 233-243
-
-
Lu, H.1
Booth, P.J.2
-
135
-
-
84866332584
-
Assembling of AcrB trimer in cell membrane
-
LU, W., CHAI, Q., ZHONG, M., YU, L., FANG, J., WANG, T., LI, H., ZHU, H.&WEI, Y. (2012). Assembling of AcrB trimer in cell membrane. Journal of Molecular Biology 423(1), 123-134.
-
(2012)
Journal of Molecular Biology
, vol.423
, Issue.1
, pp. 123-134
-
-
Lu, W.1
Chai, Q.2
Zhong, M.3
Yu, L.4
Fang, J.5
Wang, T.6
Li, H.7
Zhu, H.8
Wei, Y.9
-
136
-
-
0031983038
-
Co-And posttranslational translocation mechanisms direct cystic fibrosis transmembrane conductance regulator N terminus transmembrane assembly
-
LU, Y., XIONG, X., HELM, A., KIMANI, K., BRAGIN, A. & SKACH, W. R. (1998). Co-And posttranslational translocation mechanisms direct cystic fibrosis transmembrane conductance regulator N terminus transmembrane assembly. Journal of Biological Chemistry 273(1), 568-576.
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.1
, pp. 568-576
-
-
Lu, Y.1
Xiong, X.2
Helm, A.3
Kimani, K.4
Bragin, A.5
Skach, W.R.6
-
137
-
-
0034492193
-
Reorientation of aquaporin-1 topology during maturation in the endoplasmic reticulum
-
LU, Y., TURNBULL, I. R., BRAGIN, A., CARVETH, K., VERKMAN, A. S. & SKACH, W. R. (2000). Reorientation of aquaporin-1 topology during maturation in the endoplasmic reticulum. Molecular Biology of the Cell 11(9), 2973-2985.
-
(2000)
Molecular Biology of the Cell
, vol.11
, Issue.9
, pp. 2973-2985
-
-
Lu, Y.1
Turnbull, I.R.2
Bragin, A.3
Carveth, K.4
Verkman, A.S.5
Skach, W.R.6
-
138
-
-
0037339478
-
Cholesterol-induced protein sorting: An analysis of energetic feasibility
-
LUNDBAEK, J. A., ANDERSEN, O. S., WERGE, T. & NIELSEN, C. (2003). Cholesterol-induced protein sorting: An analysis of energetic feasibility. Biophysical Journal 84(3), 2080-2089.
-
(2003)
Biophysical Journal
, vol.84
, Issue.3
, pp. 2080-2089
-
-
Lundbaek, J.A.1
Andersen, O.S.2
Werge, T.3
Nielsen, C.4
-
139
-
-
33947356717
-
ERp57 and PDI: Multifunctional protein disulfide isomerases with similar domain architectures but differing substrate-partner associations
-
MAATTANEN, P., KOZLOV, G., GEHRING, K. & THOMAS, D. Y. (2006). ERp57 and PDI: Multifunctional protein disulfide isomerases with similar domain architectures but differing substrate-partner associations. Biochemistry and Cell Biology 84 (6), 881-889.
-
(2006)
Biochemistry and Cell Biology
, vol.84
, Issue.6
, pp. 881-889
-
-
Maattanen, P.1
Kozlov, G.2
Gehring, K.3
Thomas, D.Y.4
-
141
-
-
84891713349
-
Pharmacological rescue of trafficking-impaired ATP-sensitive potassium channels
-
MARTIN, G. M., CHEN, P. C., DEVARANENI, P. & SHYNG, S. L. (2013). Pharmacological rescue of trafficking-impaired ATP-sensitive potassium channels. Frontiers in Physiology 4, 386.
-
(2013)
Frontiers in Physiology
, vol.4
, pp. 386
-
-
Martin, G.M.1
Chen, P.C.2
Devaraneni, P.3
Shyng, S.L.4
-
142
-
-
33750459691
-
Dynamic helix interactions in transmembrane signaling
-
MATTHEWS, E. E., ZOONENS, M. & ENGELMAN, D.M. (2006). Dynamic helix interactions in transmembrane signaling. Cell 127(3), 447-450.
-
(2006)
Cell
, vol.127
, Issue.3
, pp. 447-450
-
-
Matthews, E.E.1
Zoonens, M.2
Engelman, D.M.3
-
143
-
-
0033559258
-
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
-
MEACHAM, G. C., LU, Z., KING, S., SORSCHER, E., TOUSSON, A. & CYR, D.M. (1999). The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis. EMBO Journal 18(6), 1492-1505.
-
(1999)
EMBO Journal
, vol.18
, Issue.6
, pp. 1492-1505
-
-
Meacham, G.C.1
Lu, Z.2
King, S.3
Sorscher, E.4
Tousson, A.5
Cyr, D.M.6
-
144
-
-
33750498869
-
Asn-And Asp-mediated interactions between transmembrane helices during translocon-mediated membrane protein assembly
-
MEINDL-BEINKER, N. M., LUNDIN, C., NILSSON, I., WHITE, S.H. & VON HEIJNE, G. (2006). Asn-And Asp-mediated interactions between transmembrane helices during translocon-mediated membrane protein assembly. EMBO Reports 7(11), 1111-1116.
-
(2006)
EMBO Reports
, vol.7
, Issue.11
, pp. 1111-1116
-
-
Meindl-Beinker, N.M.1
Lundin, C.2
Nilsson, I.3
White, S.H.4
Von Heijne, G.5
-
145
-
-
84878986182
-
Specificity and regulation of the endoplasmic reticulum-Associated degradation machinery
-
MERULLA, J., FASANA, E., SOLDA, T. & MOLINARI, M. (2013). Specificity and regulation of the endoplasmic reticulum-Associated degradation machinery. Traffic 14(7), 767-777.
-
(2013)
Traffic
, vol.14
, Issue.7
, pp. 767-777
-
-
Merulla, J.1
Fasana, E.2
Solda, T.3
Molinari, M.4
-
146
-
-
30944461855
-
Hide and run Arginine-based endoplasmic-reticulum-sorting motifs in the assembly of heteromultimeric membrane proteins
-
MICHELSEN, K., YUAN, H. & SCHWAPPACH, B. (2005). Hide and run. Arginine-based endoplasmic-reticulum-sorting motifs in the assembly of heteromultimeric membrane proteins. EMBO Reports 6(8), 717-722.
-
(2005)
EMBO Reports
, vol.6
, Issue.8
, pp. 717-722
-
-
Michelsen, K.1
Yuan, H.2
Schwappach, B.3
-
147
-
-
77955984919
-
Internally bridging water molecule in transmembrane alphahelical kink
-
MIYANO, M., AGO, H., SAINO, H., HORI, T. & IDA, K. (2010). Internally bridging water molecule in transmembrane alphahelical kink. Current Opinion in Structural Biology 20(4), 456-463.
-
(2010)
Current Opinion in Structural Biology
, vol.20
, Issue.4
, pp. 456-463
-
-
Miyano, M.1
Ago, H.2
Saino, H.3
Hori, T.4
Ida, K.5
-
148
-
-
1342334746
-
Contrasting functions of calreticulin and calnexin in glycoprotein folding and ER quality control
-
MOLINARI, M., ERIKSSON, K. K., CALANCA, V., GALLI, C., CRESSWELL, P., MICHALAK, M. & HELENIUS, A. (2004). Contrasting functions of calreticulin and calnexin in glycoprotein folding and ER quality control. Molecular Cell 13(1), 125-135.
-
(2004)
Molecular Cell
, vol.13
, Issue.1
, pp. 125-135
-
-
Molinari, M.1
Eriksson, K.K.2
Calanca, V.3
Galli, C.4
Cresswell, P.5
Michalak, M.6
Helenius, A.7
-
150
-
-
80054719797
-
Overcoming hysteresis to attain reversible equilibrium folding for outer membrane phospholipase A in phospholipid bilayers
-
MOON, C. P., KWON, S. & FLEMING, K. G. (2011). Overcoming hysteresis to attain reversible equilibrium folding for outer membrane phospholipase A in phospholipid bilayers. Journal of Molecular Biology 413(2), 484-494.
-
(2011)
Journal of Molecular Biology
, vol.413
, Issue.2
, pp. 484-494
-
-
Moon, C.P.1
Kwon, S.2
Fleming, K.G.3
-
151
-
-
0034118221
-
Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants
-
MORELLO, J. P., SALAHPOUR, A., LAPERRIERE, A., BERNIER, V., ARTHUS, M. F., LONERGAN, M., PETAJA-REPO, U., ANGERS, S., MORIN, D., BICHET, D.G. & BOUVIER, M. (2000). Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants. Journal of Clinical Investigation 105(7), 887-895.
-
(2000)
Journal of Clinical Investigation
, vol.105
, Issue.7
, pp. 887-895
-
-
Morello, J.P.1
Salahpour, A.2
Laperriere, A.3
Bernier, V.4
Arthus, M.F.5
Lonergan, M.6
Petaja-Repo, U.7
Angers, S.8
Morin, D.9
Bichet, D.G.10
Bouvier, M.11
-
152
-
-
0031686961
-
Coupled translocation events generate topological heterogeneity at the endoplasmic reticulum membrane
-
MOSS, K., HELM, A., LU, Y., BRAGIN, A. & SKACH, W. R. (1998). Coupled translocation events generate topological heterogeneity at the endoplasmic reticulum membrane. Molecular Biology of the Cell 9(9), 2681-2697.
-
(1998)
Molecular Biology of the Cell
, vol.9
, Issue.9
, pp. 2681-2697
-
-
Moss, K.1
Helm, A.2
Lu, Y.3
Bragin, A.4
Skach, W.R.5
-
153
-
-
50249175120
-
Chemical and biological approaches synergize to ameliorate protein-folding diseases
-
MU, T.W., ONG, D. S., WANG, Y. J., BALCH, W. E., YATES, J. R. III, SEGATORI, L. & KELLY, J.W. (2008). Chemical and biological approaches synergize to ameliorate protein-folding diseases. Cell 134(5), 769-781.
-
(2008)
Cell
, vol.134
, Issue.5
, pp. 769-781
-
-
Mu, T.W.1
Ong, D.S.2
Wang, Y.J.3
Balch, W.E.4
Yates, J.R.5
Segatori, L.6
Kelly, J.W.7
-
154
-
-
53249125616
-
The peripheral neuropathy-linked Trembler and Trembler-J mutant forms of peripheral myelin protein 22 are folding-destabilized
-
MYERS, J. K., MOBLEY, C.K. & SANDERS, C. R. (2008). The peripheral neuropathy-linked Trembler and Trembler-J mutant forms of peripheral myelin protein 22 are folding-destabilized. Biochemistry 47(40), 10620-10629.
-
(2008)
Biochemistry
, vol.47
, Issue.40
, pp. 10620-10629
-
-
Myers, J.K.1
Mobley, C.K.2
Sanders, C.R.3
-
155
-
-
0032894049
-
Impaired intracellular trafficking is a common disease mechanism of PMP22 point mutations in peripheral neuropathies
-
NAEF, R. & SUTER, U. (1999). Impaired intracellular trafficking is a common disease mechanism of PMP22 point mutations in peripheral neuropathies. Neurobiology of Disease 6(1), 1-14.
-
(1999)
Neurobiology of Disease
, vol.6
, Issue.1
, pp. 1-14
-
-
Naef, R.1
Suter, U.2
-
156
-
-
0037162394
-
A critical residue in the folding pathway of an integral membrane protein
-
NAGY, J.K. & SANDERS, C. R. (2002). A critical residue in the folding pathway of an integral membrane protein. Biochemistry 41(29), 9021-9025.
-
(2002)
Biochemistry
, vol.41
, Issue.29
, pp. 9021-9025
-
-
Nagy, J.K.1
Sanders, C.R.2
-
157
-
-
0347988157
-
Destabilizing mutations promote membrane protein misfolding
-
NAGY, J.K. & SANDERS, C. R. (2004). Destabilizing mutations promote membrane protein misfolding. Biochemistry 43(1), 19-25.
-
(2004)
Biochemistry
, vol.43
, Issue.1
, pp. 19-25
-
-
Nagy, J.K.1
Sanders, C.R.2
-
158
-
-
77955584707
-
Modulation of the oligomerization of myelin proteolipid protein by transmembrane helix interaction motifs
-
NG, D.P. & DEBER, C.M. (2010). Modulation of the oligomerization of myelin proteolipid protein by transmembrane helix interaction motifs. Biochemistry 49(32), 6896-6902.
-
(2010)
Biochemistry
, vol.49
, Issue.32
, pp. 6896-6902
-
-
Ng, D.P.1
Deber, C.M.2
-
159
-
-
84857656752
-
Membrane protein misassembly in disease
-
NG, D. P., POULSEN, B.E. & DEBER, C.M. (2012). Membrane protein misassembly in disease. Biochimica et Biophysica Acta 1818(4), 1115-1122.
-
(2012)
Biochimica et Biophysica Acta
, vol.1818
, Issue.4
, pp. 1115-1122
-
-
Ng, D.P.1
Poulsen, B.E.2
Deber, C.M.3
-
160
-
-
0032752558
-
PMP22 accumulation in aggresomes: Implications for CMT1A pathology
-
NOTTERPEK, L., RYAN, M. C., TOBLER, A.R. & SHOOTER, E.M. (1999). PMP22 accumulation in aggresomes: Implications for CMT1A pathology. Neurobiology of Disease 6(5), 450-460.
-
(1999)
Neurobiology of Disease
, vol.6
, Issue.5
, pp. 450-460
-
-
Notterpek, L.1
Ryan, M.C.2
Tobler, A.R.3
Shooter, E.M.4
-
161
-
-
84884967922
-
Discovery of novel potent DeltaF508-CFTR correctors that target the nucleotide binding domain
-
ODOLCZYK, N., FRITSCH, J., NOREZ, C., SERVEL, N., DA CUNHA, M. F., BITAM, S., KUPNIEWSKA, A., WISZNIEWSKI, L., COLAS, J., TARNOWSKI, K., TONDELIER, D., ROLDAN, A., SAUSSEREAU, E. L., MELIN-HESCHEL, P., WIECZOREK, G., LUKACS, G. L., DADLEZ, M., FAURE, G., HERRMANN, H., OLLERO, M., BECQ, F., ZIELENKIEWICZ, P. & EDELMAN, A. (2013). Discovery of novel potent DeltaF508-CFTR correctors that target the nucleotide binding domain. EMBO Molecular Medicine 5(10), 1484-1501.
-
(2013)
EMBO Molecular Medicine
, vol.5
, Issue.10
, pp. 1484-1501
-
-
Odolczyk, N.1
Fritsch, J.2
Norez, C.3
Servel, N.4
Cunha M F, D.A.5
Bitam, S.6
Kupniewska, A.7
Wiszniewski, L.8
Colas, J.9
Tarnowski, K.10
Tondelier, D.11
Roldan, A.12
Saussereau, E.L.13
Melin-Heschel, P.14
Wieczorek, G.15
Lukacs, G.L.16
Dadlez, M.17
Faure, G.18
Herrmann, H.19
Ollero, M.20
Becq, F.21
Zielenkiewicz, P.22
Edelman, A.23
more..
-
162
-
-
79961238544
-
Apolar surface area determines the efficiency of translocon-mediated membrane-protein integration into the endoplasmic reticulum
-
OJEMALM K. HIGUCHI T. JIANG Y. LANGEL U. NILSSON I. WHITE S. H. SUGA H. VON HEIJNE G. 2011 Apolar surface area determines the efficiency of translocon-mediated membrane-protein integration into the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America 108 31 E359-E364.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.31
, pp. E359-E364
-
-
Ojemalm, K.1
Higuchi, T.2
Jiang, Y.3
Langel, U.4
Nilsson, I.5
White, S.H.6
Suga, H.7
Von Heijne, G.8
-
163
-
-
84870763849
-
The mammalian endoplasmic reticulum-Associated degradation system
-
OLZMANN, J. A., KOPITO, R.R. & CHRISTIANSON, J. C. (2013). The mammalian endoplasmic reticulum-Associated degradation system. Cold Spring Harbor Perspectives in Biology 5(9), 1-16.
-
(2013)
Cold Spring Harbor Perspectives in Biology
, vol.5
, Issue.9
, pp. 1-16
-
-
Olzmann, J.A.1
Kopito, R.R.2
Christianson, J.C.3
-
164
-
-
79954416821
-
Chemical and/or biological therapeutic strategies to ameliorate protein misfolding diseases
-
ONG, D. S. & KELLY, J.W. (2011). Chemical and/or biological therapeutic strategies to ameliorate protein misfolding diseases. Current Opinion in Cell Biology 23(2), 231-238.
-
(2011)
Current Opinion in Cell Biology
, vol.23
, Issue.2
, pp. 231-238
-
-
Ong, D.S.1
Kelly, J.W.2
-
165
-
-
77952580752
-
Life and death of a BiP substrate
-
OTERO, J. H., LIZAK, B. & HENDERSHOT, L.M. (2010). Life and death of a BiP substrate. Seminars in Cell and Developmental Biology 21(5), 472-478.
-
(2010)
Seminars in Cell and Developmental Biology
, vol.21
, Issue.5
, pp. 472-478
-
-
Otero, J.H.1
Lizak, B.2
Hendershot, L.M.3
-
166
-
-
0041743087
-
Folding of DsbB in mixed micelles: A kinetic analysis of the stability of a bacterial membrane protein
-
OTZEN, D. (2003). Folding of DsbB in mixed micelles: A kinetic analysis of the stability of a bacterial membrane protein. Journal of Molecular Biology 330(4), 641-649.
-
(2003)
Journal of Molecular Biology
, vol.330
, Issue.4
, pp. 641-649
-
-
Otzen, D.1
-
167
-
-
78650454699
-
Mapping the folding pathway of the transmembrane protein DsbB by protein engineering
-
OTZEN, D. E. (2011). Mapping the folding pathway of the transmembrane protein DsbB by protein engineering. Protein Engineering Design and Selection 24(1-2), 139-149.
-
(2011)
Protein Engineering Design and Selection
, vol.24
, Issue.1-2
, pp. 139-149
-
-
Otzen, D.E.1
-
168
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
OZCAN, U., YILMAZ, E., OZCAN, L., FURUHASHI, M., VAILLANCOURT, E., SMITH, R. O., GORGUN, C.Z. & HOTAMISLIGIL, G. S. (2006). Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 313(5790), 1137-1140.
-
(2006)
Science
, vol.313
, Issue.5790
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Gorgun, C.Z.7
Hotamisligil, G.S.8
-
169
-
-
0030754830
-
Neurons promote the translocation of peripheral myelin protein 22 into myelin
-
PAREEK, S., NOTTERPEK, L., SNIPES, G. J., NAEF, R., SOSSIN, W., LALIBERT', J., IACAMPO, S., SUTER, U., SHOOTER, E.M. & MURPHY, R. A. (1997). Neurons promote the translocation of peripheral myelin protein 22 into myelin. Journal of Neuroscience 17(20), 7754-7762.
-
(1997)
Journal of Neuroscience
, vol.17
, Issue.20
, pp. 7754-7762
-
-
Pareek, S.1
Notterpek, L.2
Snipes, G.J.3
Naef, R.4
Sossin, W.5
Lalibert, J.6
Iacampo, S.7
Suter, U.8
Shooter, E.M.9
Murphy, R.A.10
-
170
-
-
34247180735
-
Energetics-based protein profiling on a proteomic scale: Identification of proteins resistant to proteolysis
-
PARK, C., ZHOU, S., GILMORE, J. & MARQUSEE, S. (2007). Energetics-based protein profiling on a proteomic scale: Identification of proteins resistant to proteolysis. Journal of Molecular Biology 368(5), 1426-1437.
-
(2007)
Journal of Molecular Biology
, vol.368
, Issue.5
, pp. 1426-1437
-
-
Park, C.1
Zhou, S.2
Gilmore, J.3
Marqusee, S.4
-
171
-
-
1542376209
-
Missense mutations in transmembrane domains of proteins: Phenotypic propensity of polar residues for human disease
-
PARTRIDGE, A.W., THERIEN, A.G. & DEBER, C.M. (2004). Missense mutations in transmembrane domains of proteins: Phenotypic propensity of polar residues for human disease. Proteins 54(4), 648-656.
-
(2004)
Proteins
, vol.54
, Issue.4
, pp. 648-656
-
-
Partridge, A.W.1
Therien, A.G.2
Deber, C.M.3
-
172
-
-
85047683541
-
Chemical chaperones: A pharmacological strategy for disorders of protein folding and trafficking
-
PERLMUTTER, D. H. (2002). Chemical chaperones: A pharmacological strategy for disorders of protein folding and trafficking. Pediatric Research 52(6), 832-836.
-
(2002)
Pediatric Research
, vol.52
, Issue.6
, pp. 832-836
-
-
Perlmutter, D.H.1
-
173
-
-
0037007201
-
Ligands act as pharmacological chaperones and increase the efficiency of delta opioid receptor maturation
-
PETAJA-REPO, U. E., HOGUE, M., BHALLA, S., LAPERRIERE, A., MORELLO, J.P. & BOUVIER, M. (2002). Ligands act as pharmacological chaperones and increase the efficiency of delta opioid receptor maturation. EMBO Journal 21(7), 1628-1637.
-
(2002)
EMBO Journal
, vol.21
, Issue.7
, pp. 1628-1637
-
-
Petaja-Repo, U.E.1
Hogue, M.2
Bhalla, S.3
Laperriere, A.4
Morello, J.P.5
Bouvier, M.6
-
174
-
-
84867327158
-
Direct assessment of the effect of the Gly380Arg achondroplasia mutation on FGFR3 dimerization using quantitative imaging FRET
-
PLACONE, J. & HRISTOVA, K. (2012). Direct assessment of the effect of the Gly380Arg achondroplasia mutation on FGFR3 dimerization using quantitative imaging FRET. PLoS ONE 7(10), e46678.
-
(2012)
PLoS ONE
, vol.7
, Issue.10
, pp. e46678
-
-
Placone, J.1
Hristova, K.2
-
175
-
-
0034687123
-
Topology, stability, sequence, and length: Defining the determinants of two-state protein folding kinetics
-
PLAXCO, K.W., SIMONS, K. T., RUCZINSKI, I. & BAKER, D. (2000). Topology, stability, sequence, and length: Defining the determinants of two-state protein folding kinetics. Biochemistry 39(37), 11177-11183.
-
(2000)
Biochemistry
, vol.39
, Issue.37
, pp. 11177-11183
-
-
Plaxco, K.W.1
Simons, K.T.2
Ruczinski, I.3
Baker, D.4
-
176
-
-
0025249842
-
Membrane protein folding and oligomerization: The two-stage model
-
POPOT, J.L. & ENGELMAN, D.M. (1990). Membrane protein folding and oligomerization: The two-stage model. Biochemistry 29(17), 4031-4037.
-
(1990)
Biochemistry
, vol.29
, Issue.17
, pp. 4031-4037
-
-
Popot, J.L.1
Engelman, D.M.2
-
177
-
-
0033790343
-
Helical membrane protein folding, stability, and evolution
-
POPOT, J.L. & ENGELMAN, D.M. (2000). Helical membrane protein folding, stability, and evolution. Annual Review of Biochemistry 69, 881-922.
-
(2000)
Annual Review of Biochemistry
, vol.69
, pp. 881-922
-
-
Popot, J.L.1
Engelman, D.M.2
-
178
-
-
0022819964
-
Reformation of crystalline purple membrane from purified bacteriorhodopsin fragments
-
POPOT, J. L., TREWHELLA, J. & ENGELMAN, D.M. (1986). Reformation of crystalline purple membrane from purified bacteriorhodopsin fragments. EMBO Journal 5(11), 3039-3044.
-
(1986)
EMBO Journal
, vol.5
, Issue.11
, pp. 3039-3044
-
-
Popot, J.L.1
Trewhella, J.2
Engelman, D.M.3
-
179
-
-
67650410543
-
Biological and chemical approaches to diseases of proteostasis deficiency
-
POWERS, E. T., MORIMOTO, R. I., DILLIN, A., KELLY, J.W. & BALCH, W. E. (2009). Biological and chemical approaches to diseases of proteostasis deficiency. Annual Review of Biochemistry 78, 959-991.
-
(2009)
Annual Review of Biochemistry
, vol.78
, pp. 959-991
-
-
Powers, E.T.1
Morimoto, R.I.2
Dillin, A.3
Kelly, J.W.4
Balch, W.E.5
-
180
-
-
0031006695
-
Localization and suppression of a kinetic defect in cystic fibrosis transmembrane conductance regulator folding
-
QU, B. H., STRICKLAND, E.H. & THOMAS, P. J. (1997). Localization and suppression of a kinetic defect in cystic fibrosis transmembrane conductance regulator folding. Journal of Biological Chemistry 272(25), 15739-15744.
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.25
, pp. 15739-15744
-
-
Qu, B.H.1
Strickland, E.H.2
Thomas, P.J.3
-
181
-
-
2442548750
-
Identification of core amino acids stabilizing rhodopsin
-
RADER, A. J., ANDERSON, G., ISIN, B., KHORANA, H. G., BAHAR, I. & KLEIN-SEETHARAMAN, J. (2004). Identification of core amino acids stabilizing rhodopsin. Proceedings of the National Academy of Sciences of the United States of America 101(19), 7246-7251.
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.19
, pp. 7246-7251
-
-
Rader, A.J.1
Anderson, G.2
Isin, B.3
Khorana, H.G.4
Bahar, I.5
Klein-Seetharaman, J.6
-
182
-
-
0035818579
-
Specificity in intracellular protein aggregation and inclusion body formation
-
RAJAN, R. S., ILLING, M. E., BENCE, N.F. & KOPITO, R. R. (2001). Specificity in intracellular protein aggregation and inclusion body formation. Proceedings of the National Academy of Sciences of the United States of America 98(23), 13060-13065.
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.23
, pp. 13060-13065
-
-
Rajan, R.S.1
Illing, M.E.2
Bence, N.F.3
Kopito, R.R.4
-
183
-
-
80455162465
-
A CFTR potentiator in patients with cystic fibrosis and the G551D mutation
-
RAMSEY, B.W., DAVIES, J., MCELVANEY, N. G., TULLIS, E., BELL, S. C., DREVINEK, P., GRIESE, M., MCKONE, E.F., WAINWRIGHT, C. E., KONSTAN, M.W., MOSS, R., RATJEN, F., SERMET-GAUDELUS, I., ROWE, S. M., DONG, Q., RODRIGUEZ, S., YEN, K., ORDONEZ, C., ELBORN, J.S. & GROUP, V. X. S. (2011). A CFTR potentiator in patients with cystic fibrosis and the G551D mutation. New England Journal of Medicine 365(18), 1663-1672.
-
(2011)
New England Journal of Medicine
, vol.365
, Issue.18
, pp. 1663-1672
-
-
Ramsey, B.W.1
Davies, J.2
McElvaney, N.G.3
Tullis, E.4
Bell, S.C.5
Drevinek, P.6
Griese, M.7
McKone, E.F.8
Wainwright, C.E.9
Konstan, M.W.10
Moss, R.11
Ratjen, F.12
Sermet-Gaudelus, I.13
Rowe, S.M.14
Dong, Q.15
Rodriguez, S.16
Yen, K.17
Ordonez, C.18
Elborn, J.S.19
-
184
-
-
0031012140
-
Slow alpha helix formation during folding of a membrane protein
-
RILEY, M., WALLACE, B., FLITSCH, S. & BOOTH, P. (1997). Slow alpha helix formation during folding of a membrane protein. Biochemistry 36(1), 192-196.
-
(1997)
Biochemistry
, vol.36
, Issue.1
, pp. 192-196
-
-
Riley, M.1
Wallace, B.2
Flitsch, S.3
Booth, P.4
-
185
-
-
30044441872
-
Rescue of vasopressin V2 receptor mutants by chemical chaperones: Specificity and mechanism
-
ROBBEN, J. H., SZE, M., KNOERS, N.V. & DEEN, P.M. (2006). Rescue of vasopressin V2 receptor mutants by chemical chaperones: Specificity and mechanism. Molecular Biology of the Cell 17(1), 379-386.
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.1
, pp. 379-386
-
-
Robben, J.H.1
Sze, M.2
Knoers, N.V.3
Deen, P.M.4
-
186
-
-
79954414554
-
Modeling general proteostasis: Proteome balance in health and disease
-
ROTH, D.M. & BALCH, W. E. (2011). Modeling general proteostasis: Proteome balance in health and disease. Current Opinion in Cell Biology 23(2), 126-134.
-
(2011)
Current Opinion in Cell Biology
, vol.23
, Issue.2
, pp. 126-134
-
-
Roth, D.M.1
Balch, W.E.2
-
187
-
-
84879000844
-
Cystic fibrosis transmembrane regulator correctors and potentiators
-
ROWE, S.M. & VERKMAN, A. S. (2013). Cystic fibrosis transmembrane regulator correctors and potentiators. Cold Spring Harbor Perspectives in Medicine 3(7), 1-15.
-
(2013)
Cold Spring Harbor Perspectives in Medicine
, vol.3
, Issue.7
, pp. 1-15
-
-
Rowe, S.M.1
Verkman, A.S.2
-
188
-
-
0036070537
-
Aggresome formation in neuropathy models based on peripheral myelin protein 22 mutations
-
RYAN, M. C., SHOOTER, E.M. & NOTTERPEK, L. (2002). Aggresome formation in neuropathy models based on peripheral myelin protein 22 mutations. Neurobiology of Disease 10(2), 109-118.
-
(2002)
Neurobiology of Disease
, vol.10
, Issue.2
, pp. 109-118
-
-
Ryan, M.C.1
Shooter, E.M.2
Notterpek, L.3
-
189
-
-
84878873024
-
Targeting unfolded protein response signaling pathways to ameliorate protein misfolding diseases
-
RYNO, L. M., WISEMAN, R.L. & KELLY, J.W. (2013). Targeting unfolded protein response signaling pathways to ameliorate protein misfolding diseases. Current Opinion in Chemical Biology 17(3), 346-352.
-
(2013)
Current Opinion in Chemical Biology
, vol.17
, Issue.3
, pp. 346-352
-
-
Ryno, L.M.1
Wiseman, R.L.2
Kelly, J.W.3
-
190
-
-
17744395499
-
Biogenesis of CFTR and other polytopic membrane proteins: New roles for the ribosome-Translocon complex
-
SADLISH, H. & SKACH, W. R. (2004). Biogenesis of CFTR and other polytopic membrane proteins: New roles for the ribosome-Translocon complex. Journal of Membrane Biology 202(3), 115-126.
-
(2004)
Journal of Membrane Biology
, vol.202
, Issue.3
, pp. 115-126
-
-
Sadlish, H.1
Skach, W.R.2
-
191
-
-
27144549973
-
Sequential triage of transmembrane segments by Sec61alpha during biogenesis of a native multispanning membrane protein
-
SADLISH, H., PITONZO, D., JOHNSON, A.E. & SKACH, W. R. (2005). Sequential triage of transmembrane segments by Sec61alpha during biogenesis of a native multispanning membrane protein. Nature Structural and Molecular Biology 12 (10), 870-878.
-
(2005)
Nature Structural and Molecular Biology
, vol.12
, Issue.10
, pp. 870-878
-
-
Sadlish, H.1
Pitonzo, D.2
Johnson, A.E.3
Skach, W.R.4
-
192
-
-
80051517324
-
Structural basis for the Trembler-J phenotype of Charcot-Marie-Tooth disease
-
SAKAKURA, M., HADZISELIMOVIC, A., WANG, Z., SCHEY, K.L. & SANDERS, C. R. (2011). Structural basis for the Trembler-J phenotype of Charcot-Marie-Tooth disease. Structure 19(8), 1160-1169.
-
(2011)
Structure
, vol.19
, Issue.8
, pp. 1160-1169
-
-
Sakakura, M.1
Hadziselimovic, A.2
Wang, Z.3
Schey, K.L.4
Sanders, C.R.5
-
193
-
-
0037099080
-
The cellular fate of mutant rhodopsin: Quality control, degradation and aggresome formation
-
SALIBA, R. S., MUNRO, P. M., LUTHERT, P. J. & CHEETHAM, M. E. (2002). The cellular fate of mutant rhodopsin: Quality control, degradation and aggresome formation. Journal of Cell Science 115(Pt 14), 2907-2918.
-
(2002)
Journal of Cell Science
, vol.115
, pp. 2907-2918
-
-
Saliba, R.S.1
Munro, P.M.2
Luthert, P.J.3
Cheetham, M.E.4
-
194
-
-
79951829938
-
Identification of a NBD1-binding pharmacological chaperone that corrects the trafficking defect of F508del-CFTR
-
SAMPSON, H. M., ROBERT, R., LIAO, J., MATTHES, E., CARLILE, G.W., HANRAHAN, J.W. & THOMAS, D. Y. (2011). Identification of a NBD1-binding pharmacological chaperone that corrects the trafficking defect of F508del-CFTR. Chemical Biology 18(2), 231-242.
-
(2011)
Chemical Biology
, vol.18
, Issue.2
, pp. 231-242
-
-
Sampson, H.M.1
Robert, R.2
Liao, J.3
Matthes, E.4
Carlile, G.W.5
Hanrahan, J.W.6
Thomas, D.Y.7
-
196
-
-
80052765949
-
Tolerance to changes in membrane lipid composition as a selected trait of membrane proteins
-
SANDERS, C.R. & MITTENDORF, K. F. (2011). Tolerance to changes in membrane lipid composition as a selected trait of membrane proteins. Biochemistry 50(37), 7858-7867.
-
(2011)
Biochemistry
, vol.50
, Issue.37
, pp. 7858-7867
-
-
Sanders, C.R.1
Mittendorf, K.F.2
-
197
-
-
0033915741
-
Misfolding of membrane proteins in health and disease: The lady or the tiger?
-
SANDERS, C.R. & NAGY, J. K. (2000). Misfolding of membrane proteins in health and disease: The lady or the tiger? Current Opinion in Structural Biology 10(4), 438-442.
-
(2000)
Current Opinion in Structural Biology
, vol.10
, Issue.4
, pp. 438-442
-
-
Sanders, C.R.1
Nagy, J.K.2
-
198
-
-
0035859867
-
Mutations of peripheral myelin protein 22 result in defective trafficking through mechanisms which may be common to diseases involving tetraspan membrane proteins
-
SANDERS, C. R., ISMAIL-BEIGI, F. & MCENERY, M.W. (2001). Mutations of peripheral myelin protein 22 result in defective trafficking through mechanisms which may be common to diseases involving tetraspan membrane proteins. Biochemistry 40(32), 9453-9459.
-
(2001)
Biochemistry
, vol.40
, Issue.32
, pp. 9453-9459
-
-
Sanders, C.R.1
Ismail-Beigi, F.2
McEnery, M.W.3
-
199
-
-
64749087257
-
Misfolded membrane proteins are specifically recognized by the transmembrane domain of the Hrd1p ubiquitin ligase
-
SATO, B. K., SCHULZ, D., DO, P.H. & HAMPTON, R. Y. (2009). Misfolded membrane proteins are specifically recognized by the transmembrane domain of the Hrd1p ubiquitin ligase. Molecular Cell 34(2), 212-222.
-
(2009)
Molecular Cell
, vol.34
, Issue.2
, pp. 212-222
-
-
Sato, B.K.1
Schulz, D.2
Do, P.H.3
Hampton, R.Y.4
-
200
-
-
0030042386
-
Glycerol reverses the misfolding phenotype of the most common cystic fibrosis mutation
-
SATO, S., WARD, C. L., KROUSE, M. E., WINE, J. J. & KOPITO, R. R. (1996). Glycerol reverses the misfolding phenotype of the most common cystic fibrosis mutation. Journal of Biological Chemistry 271(2), 635-638.
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.2
, pp. 635-638
-
-
Sato, S.1
Ward, C.L.2
Krouse, M.E.3
Wine, J.J.4
Kopito, R.R.5
-
201
-
-
0037180511
-
Chemical chaperones increase the cellular activity of N370S beta-glucosidase: A therapeutic strategy for Gaucher disease
-
SAWKAR, A. R., CHENG, W. C., BEUTLER, E., WONG, C. H., BALCH, W.E. & KELLY, J.W. (2002). Chemical chaperones increase the cellular activity of N370S beta-glucosidase: A therapeutic strategy for Gaucher disease. Proceedings of the National Academy of Sciences of the United States of America 99(24), 15428-15433.
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.24
, pp. 15428-15433
-
-
Sawkar, A.R.1
Cheng, W.C.2
Beutler, E.3
Wong, C.H.4
Balch, W.E.5
Kelly, J.W.6
-
202
-
-
79951681719
-
Probing membrane protein unfolding with pulse proteolysis
-
SCHLEBACH, J. P., KIM, M. S., JOH, N. H., BOWIE, J.U. & PARK, C. (2011). Probing membrane protein unfolding with pulse proteolysis. Journal of Molecular Biology 406(4), 545-551.
-
(2011)
Journal of Molecular Biology
, vol.406
, Issue.4
, pp. 545-551
-
-
Schlebach, J.P.1
Kim, M.S.2
Joh, N.H.3
Bowie, J.U.4
Park, C.5
-
203
-
-
84455204151
-
Revisiting the folding kinetics of bacteriorhodopsin
-
SCHLEBACH, J. P., CAO, Z., BOWIE, J.U. & PARK, C. (2012). Revisiting the folding kinetics of bacteriorhodopsin. Protein Science 21(1), 97-106.
-
(2012)
Protein Science
, vol.21
, Issue.1
, pp. 97-106
-
-
Schlebach, J.P.1
Cao, Z.2
Bowie, J.U.3
Park, C.4
-
204
-
-
84877790199
-
Reversible folding of human peripheral myelin protein 22, a tetraspan membrane protein
-
SCHLEBACH, J. P., PENG, D., KRONCKE, B. M., MITTENDORF, K. F., NARAYAN, M., CARTER, B.D. & SANDERS, C. R. (2013). Reversible folding of human peripheral myelin protein 22, a tetraspan membrane protein. Biochemistry 52(19), 3229-3241.
-
(2013)
Biochemistry
, vol.52
, Issue.19
, pp. 3229-3241
-
-
Schlebach, J.P.1
Peng, D.2
Kroncke, B.M.3
Mittendorf, K.F.4
Narayan, M.5
Carter, B.D.6
Sanders, C.R.7
-
205
-
-
0037459073
-
Protein translocons: Multifunctional mediators of protein translocation across membranes
-
SCHNELL, D. J. & HEBERT, D. N. (2003). Protein translocons: Multifunctional mediators of protein translocation across membranes. Cell 112(4), 491-505.
-
(2003)
Cell
, vol.112
, Issue.4
, pp. 491-505
-
-
Schnell, D.J.1
Hebert, D.N.2
-
206
-
-
25444474165
-
Using micellar mole fractions to assess membrane protein stability in mixed micelles
-
SEHGAL, P., MOGENSEN, J.E. & OTZEN, D. E. (2005). Using micellar mole fractions to assess membrane protein stability in mixed micelles. Biochimica et Biophysica Acta 1716(1), 59-68.
-
(2005)
Biochimica et Biophysica Acta
, vol.1716
, Issue.1
, pp. 59-68
-
-
Sehgal, P.1
Mogensen, J.E.2
Otzen, D.E.3
-
207
-
-
17044402604
-
The biological and chemical basis for tissue-selective amyloid disease
-
SEKIJIMA, Y., WISEMAN, R. L., MATTESON, J., HAMMARSTROM, P., MILLER, S. R., SAWKAR, A. R., BALCH, W.E. & KELLY, J.W. (2005). The biological and chemical basis for tissue-selective amyloid disease. Cell 121(1), 73-85.
-
(2005)
Cell
, vol.121
, Issue.1
, pp. 73-85
-
-
Sekijima, Y.1
Wiseman, R.L.2
Matteson, J.3
Hammarstrom, P.4
Miller, S.R.5
Sawkar, A.R.6
Balch, W.E.7
Kelly, J.W.8
-
208
-
-
0347987853
-
Folding proteins in fatal ways
-
SELKOE, D. J. (2003). Folding proteins in fatal ways. Nature 426(6968), 900-904.
-
(2003)
Nature
, vol.426
, Issue.6968
, pp. 900-904
-
-
Selkoe, D.J.1
-
209
-
-
0027408231
-
Mutations in CFTR associated with mild-disease-form Cl-channels with altered pore properties
-
SHEPPARD, D. N., RICH, D. P., OSTEDGAARD, L. S., GREGORY, R. J., SMITH, A.E. &WELSH, M. J. (1993). Mutations in CFTR associated with mild-disease-form Cl-channels with altered pore properties. Nature 362(6416), 160-164.
-
(1993)
Nature
, vol.362
, Issue.6416
, pp. 160-164
-
-
Sheppard, D.N.1
Rich, D.P.2
Ostedgaard, L.S.3
Gregory, R.J.4
Smith, A.E.5
Welsh, M.J.6
-
210
-
-
0027512232
-
Evidence for an alternate model of human P-glycoprotein structure and biogenesis
-
SKACH, W. R., CALAYAG, M.C. & LINGAPPA, V. R. (1993). Evidence for an alternate model of human P-glycoprotein structure and biogenesis. Journal of Biological Chemistry 268(10), 6903-6908.
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.10
, pp. 6903-6908
-
-
Skach, W.R.1
Calayag, M.C.2
Lingappa, V.R.3
-
211
-
-
0028318283
-
Biogenesis and transmembrane topology of the CHIP28 water channel at the endoplasmic reticulum
-
SKACH, W. R., SHI, L. B., CALAYAG, M. C., FRIGERI, A., LINGAPPA, V.R. & VERKMAN, A. S. (1994). Biogenesis and transmembrane topology of the CHIP28 water channel at the endoplasmic reticulum. Journal of Cell Biology 125(4), 803-815.
-
(1994)
Journal of Cell Biology
, vol.125
, Issue.4
, pp. 803-815
-
-
Skach, W.R.1
Shi, L.B.2
Calayag, M.C.3
Frigeri, A.4
Lingappa, V.R.5
Verkman, A.S.6
-
212
-
-
1842561598
-
The organization of engaged and quiescent translocons in the endoplasmic reticulum of mammalian cells
-
SNAPP, E. L., REINHART, G. A., BOGERT, B. A., LIPPINCOTT-SCHWARTZ, J. & HEGDE, R. S. (2004). The organization of engaged and quiescent translocons in the endoplasmic reticulum of mammalian cells. Journal of Cell Biology 164(7), 997-1007.
-
(2004)
Journal of Cell Biology
, vol.164
, Issue.7
, pp. 997-1007
-
-
Snapp, E.L.1
Reinhart, G.A.2
Bogert, B.A.3
Lippincott-Schwartz, J.4
Hegde, R.S.5
-
213
-
-
84892865694
-
Sorting out the trash: The spatial nature of eukaryotic protein quality control
-
SONTAG, E. M., VONK, W. I. & FRYDMAN, J. (2014). Sorting out the trash: The spatial nature of eukaryotic protein quality control. Current Opinion in Cell Biology 26C, 139-146.
-
(2014)
Current Opinion in Cell Biology
, vol.26 C
, pp. 139-146
-
-
Sontag, E.M.1
Vonk, W.I.2
Frydman, J.3
-
214
-
-
84901948488
-
Pharmacological chaperoning of nAChRs: A therapeutic target for Parkinson's disease
-
SRINIVASAN, R., HENDERSON, B. J., LESTER, H.A. & RICHARDS, C. I. (2014). Pharmacological chaperoning of nAChRs: A therapeutic target for Parkinson's disease. Pharmacological Research 83, 20-29.
-
(2014)
Pharmacological Research
, vol.83
, pp. 20-29
-
-
Srinivasan, R.1
Henderson, B.J.2
Lester, H.A.3
Richards, C.I.4
-
215
-
-
36749026606
-
The process of folding proteins into membranes: Challenges and progress
-
STANLEY, A. & FLEMING, K. (2008). The process of folding proteins into membranes: Challenges and progress. Archives of Biochemistry and Biophysics 469(1), 46-66.
-
(2008)
Archives of Biochemistry and Biophysics
, vol.469
, Issue.1
, pp. 46-66
-
-
Stanley, A.1
Fleming, K.2
-
216
-
-
33846008398
-
Derlin-1 promotes the efficient degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR folding mutants
-
SUN, F., ZHANG, R., GONG, X., GENG, X., DRAIN, P.F. & FRIZZELL, R. A. (2006). Derlin-1 promotes the efficient degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR folding mutants. Journal of Biological Chemistry 281(48), 36856-36863.
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.48
, pp. 36856-36863
-
-
Sun, F.1
Zhang, R.2
Gong, X.3
Geng, X.4
Drain, P.F.5
Frizzell, R.A.6
-
217
-
-
0026058548
-
Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa
-
SUNG, C. H., SCHNEIDER, B. G., AGARWAL, N., PAPERMASTER, D. S. & NATHANS, J. (1991). Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa. Proceedings of the National Academy of Sciences of the United States of America 88(19), 8840-8844.
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.19
, pp. 8840-8844
-
-
Sung, C.H.1
Schneider, B.G.2
Agarwal, N.3
Papermaster, D.S.4
Nathans, J.5
-
218
-
-
0028902548
-
Biology and genetics of hereditary motor and sensory neuropathies
-
SUTER, U. & SNIPES, G. J. (1995). Biology and genetics of hereditary motor and sensory neuropathies. Annual Review of Neuroscience 18, 45-75.
-
(1995)
Annual Review of Neuroscience
, vol.18
, pp. 45-75
-
-
Suter, U.1
Snipes, G.J.2
-
219
-
-
0026554289
-
A leucine-To-proline mutation in the putative first transmembrane domain of the 22-kDa peripheral myelin protein in the trembler-J mouse
-
SUTER, U., MOSKOW, J. J., WELCHER, A. A., SNIPES, G. J., KOSARAS, B., SIDMAN, R. L., BUCHBERG, A.M. & SHOOTER, E.M. (1992). A leucine-To-proline mutation in the putative first transmembrane domain of the 22-kDa peripheral myelin protein in the trembler-J mouse. Proceedings of the National Academy of Sciences of the United States of America 89(10), 4382-4386.
-
(1992)
Proceedings of the National Academy of Sciences of the United States of America
, vol.89
, Issue.10
, pp. 4382-4386
-
-
Suter, U.1
Moskow, J.J.2
Welcher, A.A.3
Snipes, G.J.4
Kosaras, B.5
Sidman, R.L.6
Buchberg, A.M.7
Shooter, E.M.8
-
220
-
-
0038037820
-
Role of calnexin in the glycan-independent quality control of proteolipid protein
-
SWANTON, E., HIGH, S. & WOODMAN, P. (2003). Role of calnexin in the glycan-independent quality control of proteolipid protein. EMBO Journal 22(12), 2948-2958.
-
(2003)
EMBO Journal
, vol.22
, Issue.12
, pp. 2948-2958
-
-
Swanton, E.1
High, S.2
Woodman, P.3
-
221
-
-
33745824614
-
ALIS are stress-induced protein storage compartments for substrates of the proteasome and autophagy
-
SZETO, J., KANIUK, N. A., CANADIEN, V., NISMAN, R., MIZUSHIMA, N., YOSHIMORI, T., BAZETT-JONES, D.P. & BRUMELL, J. H. (2006). ALIS are stress-induced protein storage compartments for substrates of the proteasome and autophagy. Autophagy 2(3), 189-199.
-
(2006)
Autophagy
, vol.2
, Issue.3
, pp. 189-199
-
-
Szeto, J.1
Kaniuk, N.A.2
Canadien, V.3
Nisman, R.4
Mizushima, N.5
Yoshimori, T.6
Bazett-Jones, D.P.7
Brumell, J.H.8
-
222
-
-
0032524048
-
Defective aquaporin-2 trafficking in nephrogenic diabetes insipidus and correction by chemical chaperones
-
TAMARAPPOO, B.K. & VERKMAN, A. S. (1998). Defective aquaporin-2 trafficking in nephrogenic diabetes insipidus and correction by chemical chaperones. Journal of Clinical Investigation 101(10), 2257-2267.
-
(1998)
Journal of Clinical Investigation
, vol.101
, Issue.10
, pp. 2257-2267
-
-
Tamarappoo, B.K.1
Verkman, A.S.2
-
223
-
-
79951680382
-
Membrane insertion and topology of the translocating chain-Associating membrane protein (TRAM)
-
TAMBORERO, S., VILAR, M., MARTINEZ-GIL, L., JOHNSON, A.E. & MINGARRO, I. (2011). Membrane insertion and topology of the translocating chain-Associating membrane protein (TRAM). Journal of Molecular Biology 406(4), 571-582.
-
(2011)
Journal of Molecular Biology
, vol.406
, Issue.4
, pp. 571-582
-
-
Tamborero, S.1
Vilar, M.2
Martinez-Gil, L.3
Johnson, A.E.4
Mingarro, I.5
-
224
-
-
84902210360
-
Chaperoning G Protein-coupled receptors: From cell biology to therapeutics
-
TAO, Y.X. & CONN, P.M. (2014). Chaperoning G Protein-coupled receptors: From cell biology to therapeutics. Endocrione Reviews er20131121.
-
(2014)
Endocrione Reviews er20131121
-
-
Tao, Y.X.1
Conn, P.M.2
-
225
-
-
84888041171
-
Yeast reveal a druggable Rsp5/Nedd4 network that ameliorates alpha-synuclein toxicity in neurons
-
TARDIFF, D. F., JUI, N. T., KHURANA, V., TAMBE, M. A., THOMPSON, M. L., CHUNG, C. Y., KAMADURAI, H. B., KIM, H.T., LANCASTER, A. K., CALDWELL, K. A., CALDWELL, G. A., ROCHET, J. C., BUCHWALD, S.L. & LINDQUIST, S. (2013). Yeast reveal a 'druggable' Rsp5/Nedd4 network that ameliorates alpha-synuclein toxicity in neurons. Science 342(6161), 979-983.
-
(2013)
Science
, vol.342
, Issue.6161
, pp. 979-983
-
-
Tardiff, D.F.1
Jui, N.T.2
Khurana, V.3
Tambe, M.A.4
Thompson, M.L.5
Chung, C.Y.6
Kamadurai, H.B.7
Kim, H.T.8
Lancaster, A.K.9
Caldwell, K.A.10
Caldwell, G.A.11
Rochet, J.C.12
Buchwald, S.L.13
Lindquist, S.14
-
227
-
-
0742322956
-
The ER protein folding sensor UDP-glucose glycoprotein-glucosyltransferase modifies substrates distant to local changes in glycoprotein conformation
-
TAYLOR, S. C., FERGUSON, A. D., BERGERON, J. J. & THOMAS, D. Y. (2004). The ER protein folding sensor UDP-glucose glycoprotein-glucosyltransferase modifies substrates distant to local changes in glycoprotein conformation. Nature Structural and Molecular Biology 11(2), 128-134.
-
(2004)
Nature Structural and Molecular Biology
, vol.11
, Issue.2
, pp. 128-134
-
-
Taylor, S.C.1
Ferguson, A.D.2
Bergeron, J.J.3
Thomas, D.Y.4
-
228
-
-
0029778556
-
Signal-mediated sorting of membrane proteins between the endoplasmic reticulum and the Golgi apparatus
-
TEASDALE, R.D. & JACKSON, M. R. (1996). Signal-mediated sorting of membrane proteins between the endoplasmic reticulum and the Golgi apparatus. Annual Review of Cell and Developmental Biology 12, 27-54.
-
(1996)
Annual Review of Cell and Developmental Biology
, vol.12
, pp. 27-54
-
-
Teasdale, R.D.1
Jackson, M.R.2
-
229
-
-
0034952420
-
Interhelical hydrogen bonds in the CFTR membrane domain
-
THERIEN, A. G., GRANT, F.E. & DEBER, C.M. (2001). Interhelical hydrogen bonds in the CFTR membrane domain. Nature Structural Biology 8(7), 597-601.
-
(2001)
Nature Structural Biology
, vol.8
, Issue.7
, pp. 597-601
-
-
Therien, A.G.1
Grant, F.E.2
Deber, C.M.3
-
230
-
-
0033559844
-
Transport of Trembler-J mutant peripheral myelin protein 22 is blocked in the intermediate compartment and affects the transport of the wild-Type protein by direct interaction
-
TOBLER, A. R., NOTTERPEK, L., NAEF, R., TAYLOR, V., SUTER, U. & SHOOTER, E.M. (1999). Transport of Trembler-J mutant peripheral myelin protein 22 is blocked in the intermediate compartment and affects the transport of the wild-Type protein by direct interaction. Journal of Neuroscience 19(6), 2027-2036.
-
(1999)
Journal of Neuroscience
, vol.19
, Issue.6
, pp. 2027-2036
-
-
Tobler, A.R.1
Notterpek, L.2
Naef, R.3
Taylor, V.4
Suter, U.5
Shooter, E.M.6
-
231
-
-
0037039362
-
Differential aggregation of the Trembler and Trembler J mutants of peripheral myelin protein 22
-
TOBLER, A. R., LIU, N., MUELLER, L. & SHOOTER, E.M. (2002). Differential aggregation of the Trembler and Trembler J mutants of peripheral myelin protein 22. Proceedings of the National Academy of Sciences of the United States of America 99(1), 483-488.
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.1
, pp. 483-488
-
-
Tobler, A.R.1
Liu, N.2
Mueller, L.3
Shooter, E.M.4
-
232
-
-
0347192985
-
X-ray structure of a protein-conducting channel
-
VAN DEN BERG, B., CLEMONS, W. M., COLLINSON, I., MODIS, Y., HARTMANN, E., HARRISON, S.C. & RAPOPORT, T. A. (2004). X-ray structure of a protein-conducting channel. Nature 427(6969), 36-44.
-
(2004)
Nature
, vol.427
, Issue.6969
, pp. 36-44
-
-
Van Den Berg, B.1
Clemons, W.M.2
Collinson, I.3
Modis, Y.4
Hartmann, E.5
Harrison, S.C.6
Rapoport, T.A.7
-
233
-
-
73249114731
-
Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770
-
VAN GOOR, F., HADIDA, S., GROOTENHUIS, P. D., BURTON, B., CAO, D., NEUBERGER, T., TURNBULL, A., SINGH, A., JOUBRAN, J., HAZLEWOOD, A., ZHOU, J., MCCARTNEY, J., ARUMUGAM, V., DECKER, C., YANG, J., YOUNG, C., OLSON, E. R., WINE, J. J., FRIZZELL, R. A., ASHLOCK, M. & NEGULESCU, P. (2009). Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770. Proceedings of the National Academy of Sciences of the United States of America 106(44), 18825-18830.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.44
, pp. 18825-18830
-
-
Van Goor, F.1
Hadida, S.2
Grootenhuis, P.D.3
Burton, B.4
Cao, D.5
Neuberger, T.6
Turnbull, A.7
Singh, A.8
Joubran, J.9
Hazlewood, A.10
Zhou, J.11
McCartney, J.12
Arumugam, V.13
Decker, C.14
Yang, J.15
Young, C.16
Olson, E.R.17
Wine, J.J.18
Frizzell, R.A.19
Ashlock, M.20
Negulescu, P.21
more..
-
234
-
-
81755163563
-
Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809
-
VAN GOOR, F., HADIDA, S., GROOTENHUIS, P. D., BURTON, B., STACK, J. H., STRALEY, K. S., DECKER, C. J., MILLER, M., MCCARTNEY, J., OLSON, E. R., WINE, J. J., FRIZZELL, R. A., ASHLOCK, M. & NEGULESCU, P. A. (2011). Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809. Proceedings of the National Academy of Sciences of the United States of America 108(46), 18843-18848.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.46
, pp. 18843-18848
-
-
Van Goor, F.1
Hadida, S.2
Grootenhuis, P.D.3
Burton, B.4
Stack, J.H.5
Straley, K.S.6
Decker, C.J.7
Miller, M.8
McCartney, J.9
Olson, E.R.10
Wine, J.J.11
Frizzell, R.A.12
Ashlock, M.13
Negulescu, P.A.14
-
235
-
-
38549173564
-
Membrane lipids: Where they are and how they behave
-
VAN MEER, G., VOELKER, D.R. & FEIGENSON, G.W. (2008). Membrane lipids: Where they are and how they behave. Nature Reviews Molecular Cell Biology 9(2), 112-124.
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.2
, pp. 112-124
-
-
Van Meer, G.1
Voelker, D.R.2
Feigenson, G.W.3
-
236
-
-
81855190805
-
The tetrameric a-helical membrane protein GlpF unfolds via a dimeric folding intermediate
-
VEERAPPAN, A., CYMER, F., KLEIN, N. & SCHNEIDER, D. (2011). The tetrameric a-helical membrane protein GlpF unfolds via a dimeric folding intermediate. Biochemistry 50(47), 10223-10230.
-
(2011)
Biochemistry
, vol.50
, Issue.47
, pp. 10223-10230
-
-
Veerappan, A.1
Cymer, F.2
Klein, N.3
Schneider, D.4
-
237
-
-
56749176947
-
One step at a time: Endoplasmic reticulum-Associated degradation
-
VEMBAR, S. S. & BRODSKY, J. L. (2008). One step at a time: Endoplasmic reticulum-Associated degradation. Nature Reviews Molecular Cell Biology 9(12), 944-957.
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.12
, pp. 944-957
-
-
Vembar, S.S.1
Brodsky, J.L.2
-
238
-
-
84904179187
-
Folding of Aquaporin 1: Multiple evidence that helix 3 can shift out of the membrane core
-
VIRKKI, M. T., AGRAWAL, N., EDSBACKER, E., CRISTOBAL, S., ELOFSSON, A. & KAUKO, A. (2014). Folding of Aquaporin 1: Multiple evidence that helix 3 can shift out of the membrane core. Protein Science 23(7), 981-992.
-
(2014)
Protein Science
, vol.23
, Issue.7
, pp. 981-992
-
-
Virkki, M.T.1
Agrawal, N.2
Edsbacker, E.3
Cristobal, S.4
Elofsson, A.5
Kauko, A.6
-
239
-
-
0000651660
-
The distribution of positively charged residues in bacterial inner membrane proteins correlates with the trans-membrane topology
-
VON HEIJNE, G. (1986). The distribution of positively charged residues in bacterial inner membrane proteins correlates with the trans-membrane topology. EMBO Journal 5(11), 3021-3027.
-
(1986)
EMBO Journal
, vol.5
, Issue.11
, pp. 3021-3027
-
-
Von Heijne, G.1
-
240
-
-
0026716643
-
Membrane protein structure prediction. Hydrophobicity analysis and the positive-inside rule
-
VON HEIJNE, G. (1992). Membrane protein structure prediction. Hydrophobicity analysis and the positive-inside rule. Journal of Molecular Biology 225(2), 487-494.
-
(1992)
Journal of Molecular Biology
, vol.225
, Issue.2
, pp. 487-494
-
-
Von Heijne, G.1
-
242
-
-
33750842131
-
Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis
-
WANG, X., VENABLE, J., LAPOINTE, P., HUTT, D. M., KOULOV, A. V., COPPINGER, J., GURKAN, C., KELLNER, W., MATTESON, J., PLUTNER, H., RIORDAN, J. R., KELLY, J.W., YATES, J.R. & BALCH, W. E. (2006). Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. Cell 127(4), 803-815.
-
(2006)
Cell
, vol.127
, Issue.4
, pp. 803-815
-
-
Wang, X.1
Venable, J.2
Lapointe, P.3
Hutt, D.M.4
Koulov, A.V.5
Coppinger, J.6
Gurkan, C.7
Kellner, W.8
Matteson, J.9
Plutner, H.10
Riordan, J.R.11
Kelly, J.W.12
Yates, J.R.13
Balch, W.E.14
-
243
-
-
0028006681
-
Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-Type and mutant proteins
-
WARD, C.L. & KOPITO, R. R. (1994). Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-Type and mutant proteins. Journal of Biological Chemistry 269(41), 25710-25718.
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.41
, pp. 25710-25718
-
-
Ward, C.L.1
Kopito, R.R.2
-
244
-
-
79958126240
-
Choosing membrane mimetics for NMR structural studies of transmembrane proteins
-
WARSCHAWSKI, D. E., ARNOLD, A. A., BEAUGRAND, M., GRAVEL, A., CHARTRAND, E. & MARCOTTE, I. (2011). Choosing membrane mimetics for NMR structural studies of transmembrane proteins. Biochimica et Biophysica Acta 1808(8), 1957-1974.
-
(2011)
Biochimica et Biophysica Acta
, vol.1808
, Issue.8
, pp. 1957-1974
-
-
Warschawski, D.E.1
Arnold, A.A.2
Beaugrand, M.3
Gravel, A.4
Chartrand, E.5
Marcotte, I.6
-
245
-
-
0030154323
-
Influence of molecular and chemical chaperones on protein folding
-
WELCH, W. J. & BROWN, C. R. (1996). Influence of molecular and chemical chaperones on protein folding. Cell Stress and Chaperones 1(2), 109-115.
-
(1996)
Cell Stress and Chaperones
, vol.1
, Issue.2
, pp. 109-115
-
-
Welch, W.J.1
Brown, C.R.2
-
246
-
-
0027162649
-
Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis
-
WELSH, M. J. & SMITH, A. E. (1993). Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis. Cell 73(7), 1251-1254.
-
(1993)
Cell
, vol.73
, Issue.7
, pp. 1251-1254
-
-
Welsh, M.J.1
Smith, A.E.2
-
247
-
-
66249121383
-
Biophysical dissection of membrane proteins
-
WHITE, S. (2009). Biophysical dissection of membrane proteins. Nature 459(7245), 344-346.
-
(2009)
Nature
, vol.459
, Issue.7245
, pp. 344-346
-
-
White, S.1
-
248
-
-
0242488929
-
Translocons, thermodynamics, and the folding of membrane proteins
-
WHITE, S. H. (2003). Translocons, thermodynamics, and the folding of membrane proteins. FEBS Letters 555(1), 116-121.
-
(2003)
FEBS Letters
, vol.555
, Issue.1
, pp. 116-121
-
-
White, S.H.1
-
250
-
-
0345593387
-
Dynamic association of proteasomal machinery with the centrosome
-
WIGLEY, W. C., FABUNMI, R. P., LEE, M. G., MARINO, C. R., MUALLEM, S., DEMARTINO, G.N. & THOMAS, P. J. (1999). Dynamic association of proteasomal machinery with the centrosome. Journal of Cell Biology 145(3), 481-490.
-
(1999)
Journal of Cell Biology
, vol.145
, Issue.3
, pp. 481-490
-
-
Wigley, W.C.1
Fabunmi, R.P.2
Lee, M.G.3
Marino, C.R.4
Muallem, S.5
Demartino, G.N.6
Thomas, P.J.7
-
251
-
-
0029738872
-
Experimentally determined hydrophobicity scale for proteins at membrane interfaces
-
WIMLEY, W.C. & WHITE, S. H. (1996). Experimentally determined hydrophobicity scale for proteins at membrane interfaces. Nature Structural Biology 3(10), 842-848.
-
(1996)
Nature Structural Biology
, vol.3
, Issue.10
, pp. 842-848
-
-
Wimley, W.C.1
White, S.H.2
-
252
-
-
23144442469
-
A new pharmacology-drugging stressed folding pathways
-
WISEMAN, R.L. & BALCH, W. E. (2005). A new pharmacology-drugging stressed folding pathways. Trends in Molecular Medicine 11(8), 347-350.
-
(2005)
Trends in Molecular Medicine
, vol.11
, Issue.8
, pp. 347-350
-
-
Wiseman, R.L.1
Balch, W.E.2
-
253
-
-
34547945951
-
Protein energetics in maturation of the early secretory pathway
-
WISEMAN, R. L., KOULOV, A., POWERS, E., KELLY, J.W. & BALCH, W. E. (2007). Protein energetics in maturation of the early secretory pathway. Current Opinion in Cell Biology 19(4), 359-367.
-
(2007)
Current Opinion in Cell Biology
, vol.19
, Issue.4
, pp. 359-367
-
-
Wiseman, R.L.1
Koulov, A.2
Powers, E.3
Kelly, J.W.4
Balch, W.E.5
-
254
-
-
36049032748
-
An adaptable standard for protein export from the endoplasmic reticulum
-
WISEMAN, R. L., POWERS, E. T., BUXBAUM, J. N., KELLY, J.W. & BALCH, W. E. (2007). An adaptable standard for protein export from the endoplasmic reticulum. Cell 131(4), 809-821.
-
(2007)
Cell
, vol.131
, Issue.4
, pp. 809-821
-
-
Wiseman, R.L.1
Powers, E.T.2
Buxbaum, J.N.3
Kelly, J.W.4
Balch, W.E.5
-
255
-
-
36849036714
-
Identifying the subproteome of kinetically stable proteins via diagonal 2D SDS/PAGE
-
XIA, K., MANNING, M., HESHAM, H., LIN, Q., BYSTROFF, C. & COL'N, W. (2007). Identifying the subproteome of kinetically stable proteins via diagonal 2D SDS/PAGE. Proceedings of the National Academy of Sciences of the United States of America 104 (44), 17329-17334.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.44
, pp. 17329-17334
-
-
Xia, K.1
Manning, M.2
Hesham, H.3
Lin, Q.4
Bystroff, C.5
Col'n, W.6
-
256
-
-
0030931382
-
Structural cues involved in endoplasmic reticulum degradation of G85E and G91R mutant cystic fibrosis transmembrane conductance regulator
-
XIONG, X., BRAGIN, A., WIDDICOMBE, J. H., COHN, J. & SKACH, W. R. (1997). Structural cues involved in endoplasmic reticulum degradation of G85E and G91R mutant cystic fibrosis transmembrane conductance regulator. Journal of Clinical Investigation 100(5), 1079-1088.
-
(1997)
Journal of Clinical Investigation
, vol.100
, Issue.5
, pp. 1079-1088
-
-
Xiong, X.1
Bragin, A.2
Widdicombe, J.H.3
Cohn, J.4
Skach, W.R.5
-
257
-
-
0035875665
-
The KDEL receptor mediates a retrieval mechanism that contributes to quality control at the endoplasmic reticulum
-
YAMAMOTO, K., FUJII, R., TOYOFUKU, Y., SAITO, T., KOSEKI, H., HSU, V.W. & AOE, T. (2001). The KDEL receptor mediates a retrieval mechanism that contributes to quality control at the endoplasmic reticulum. EMBO Journal 20(12), 3082-3091.
-
(2001)
EMBO Journal
, vol.20
, Issue.12
, pp. 3082-3091
-
-
Yamamoto, K.1
Fujii, R.2
Toyofuku, Y.3
Saito, T.4
Koseki, H.5
Hsu, V.W.6
Aoe, T.7
-
258
-
-
34848865082
-
Effect of pathogenic cysteine mutations on FGFR3 transmembrane domain dimerization in detergents and lipid bilayers
-
YOU, M., SPANGLER, J., LI, E., HAN, X., GHOSH, P. & HRISTOVA, K. (2007). Effect of pathogenic cysteine mutations on FGFR3 transmembrane domain dimerization in detergents and lipid bilayers. Biochemistry 46(39), 11039-11046.
-
(2007)
Biochemistry
, vol.46
, Issue.39
, pp. 11039-11046
-
-
You, M.1
Spangler, J.2
Li, E.3
Han, X.4
Ghosh, P.5
Hristova, K.6
-
259
-
-
34748914170
-
Pharmacologic chaperoning as a strategy to treat Gaucher disease
-
YU, Z., SAWKAR, A.R. & KELLY, J.W. (2007). Pharmacologic chaperoning as a strategy to treat Gaucher disease. FEBS Journal 274(19), 4944-4950.
-
(2007)
FEBS Journal
, vol.274
, Issue.19
, pp. 4944-4950
-
-
Yu, Z.1
Sawkar, A.R.2
Kelly, J.W.3
-
260
-
-
84877773919
-
Influences of membrane mimetic environments on membrane protein structures
-
ZHOU, H.X. & CROSS, T. A. (2013). Influences of membrane mimetic environments on membrane protein structures. Annual Review of Biophysics 42, 361-392.
-
(2013)
Annual Review of Biophysics
, vol.42
, pp. 361-392
-
-
Zhou, H.X.1
Cross, T.A.2
-
261
-
-
84870896671
-
Cholesterol increases kinetic, energetic, and mechanical stability of the human beta2-Adrenergic receptor
-
ZOCHER, M., ZHANG, C., RASMUSSEN, S. G., KOBILKA, B.K. & MULLER, D. J. (2012). Cholesterol increases kinetic, energetic, and mechanical stability of the human beta2-Adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America 109(50), E3463-E3472.
-
(2012)
Proceedings of the National Academy of Sciences of the United States of America
, vol.109
, Issue.50
, pp. E3463-E3472
-
-
Zocher, M.1
Zhang, C.2
Rasmussen, S.G.3
Kobilka, B.K.4
Muller, D.J.5
|