Structure and function in rhodopsin: Further elucidation of the role of the intradiscal cysteines, Cys-110, -185, and -187, in rhodopsin folding and function

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 5, 1999, Pages 1932-1935

  Hwa, John ^a   Reeves, Philip J ^a   Klein Seetharaman, Judith ^a   Davidson, Florence ^a,b   Khorana, H Gobind ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

11 cis retinal; G protein coupled receptors; Misfolding; Retinitis pigmentosa; Signal transduction

Indexed keywords

11 CIS RETINAL; CYSTEINE; RETINAL; RHODOPSIN;

AMINO ACID SUBSTITUTION; ARTICLE; DISULFIDE BOND; GENE EXPRESSION; GENE MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; RETINITIS PIGMENTOSA; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CATTLE; CYSTEINE; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OPSIN; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; RETINITIS PIGMENTOSA; RHODOPSIN; SPECTROPHOTOMETRY;

MAMMALIA; STAPHYLOCOCCUS PHAGE 187;

EID: 0033515036     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.5.1932     Document Type: Article

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