-
1
-
-
0036795563
-
Molecular mechanism of P-glycoprotein assembly into cellular membranes
-
V. Anthony W.R. Skach 2002 Molecular mechanism of P-glycoprotein assembly into cellular membranes Curr. Prot. Pept. Sci. 3 485 501
-
(2002)
Curr. Prot. Pept. Sci.
, vol.3
, pp. 485-501
-
-
Anthony, V.1
Skach, W.R.2
-
4
-
-
0035798359
-
Architecture of the protein-conducting channel associated with the translating 80S ribosome
-
R. Beckmann C.M. Spahn N. Eswar J. Helmers P.A. Penczek A. Sali J. Frank G. Blobel 2001 Architecture of the protein-conducting channel associated with the translating 80S ribosome Cell 107 361 372
-
(2001)
Cell
, vol.107
, pp. 361-372
-
-
Beckmann, R.1
Spahn, C.M.2
Eswar, N.3
Helmers, J.4
Penczek, P.A.5
Sali, A.6
Frank, J.7
Blobel, G.8
-
5
-
-
0029048812
-
Multidrug resistance protein (Mdr)-alkaline phosphatase hybrids in Escherichia coli suggest a major revision in the topology of the C-terminal half of Mdr
-
O. Beja E. Bibi 1995 Multidrug resistance protein (Mdr)-alkaline phosphatase hybrids in Escherichia coli suggest a major revision in the topology of the C-terminal half of Mdr J. Biol. Chem. 270 12351 12354
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12351-12354
-
-
Beja, O.1
Bibi, E.2
-
6
-
-
0030064680
-
A two step recognition of signal sequences determines the translocation efficiency of proteins
-
D. Belin S. Bost J.-D. Vassalli K. Strub 1996 A two step recognition of signal sequences determines the translocation efficiency of proteins EMBO J. 15 468 478
-
(1996)
EMBO J.
, vol.15
, pp. 468-478
-
-
Belin, D.1
Bost, S.2
Vassalli, J.-D.3
Strub, K.4
-
7
-
-
0027381009
-
Functional expression of mouse mdr1 in Escherichia coli
-
E. Bibi P. Gros H.R. Kaback 1993 Functional expression of mouse mdr1 in Escherichia coli Natl. Acad. Sci. USA 90 9209 9213
-
(1993)
Natl. Acad. Sci. USA
, vol.90
, pp. 9209-9213
-
-
Bibi, E.1
Gros, P.2
Kaback, H.R.3
-
8
-
-
0018987976
-
Intracellular protein topogenesis
-
G. Blobel 1980 Intracellular protein topogenesis Proc. Natl. Acad. Sci. USA 77 1496 1500
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 1496-1500
-
-
Blobel, G.1
-
9
-
-
0029894267
-
Biogenesis of polytopic membrane proteins: Membrane segments assemble within translocation channels prior to membrane integration
-
A.C. Borel S.M. Simon 1996 Biogenesis of polytopic membrane proteins: membrane segments assemble within translocation channels prior to membrane integration Cell 85 379 389
-
(1996)
Cell
, vol.85
, pp. 379-389
-
-
Borel, A.C.1
Simon, S.M.2
-
10
-
-
0037043724
-
Three-dimensional structure of the bacterial protein-translocation complex SecYEG
-
C. Breyton W. Haase T. Rapoport W. Kuehlbrandt I. Collinson 2002 Three-dimensional structure of the bacterial protein-translocation complex SecYEG Nature 418 662 665
-
(2002)
Nature
, vol.418
, pp. 662-665
-
-
Breyton, C.1
Haase, W.2
Rapoport, T.3
Kuehlbrandt, W.4
Collinson, I.5
-
11
-
-
0037131183
-
Cooperativity and flexibility of cystic fibrosis transmembrane conductance regulator transmembrane segments participate in membrane localization of a charged residue
-
K. Carveth T. Buck V. Anthony W.R. Skach 2002 Cooperativity and flexibility of cystic fibrosis transmembrane conductance regulator transmembrane segments participate in membrane localization of a charged residue J. Biol. Chem. 277 39507 39514
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39507-39514
-
-
Carveth, K.1
Buck, T.2
Anthony, V.3
Skach, W.R.4
-
12
-
-
0022972654
-
Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells
-
C.J. Chen J.E. Chin K. Ueda D.P. Clark I. Pastan I.B. Gottesman M.M. Roninson 1986 Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells Cell 47 381 389
-
(1986)
Cell
, vol.47
, pp. 381-389
-
-
Chen, C.J.1
Chin, J.E.2
Ueda, K.3
Clark, D.P.4
Pastan, I.5
Gottesman, I.B.6
Roninson, M.M.7
-
13
-
-
0033609038
-
Topogenesis of cystic fibrosis transmembrane conductance regulator (CFTR): Regulation by the amino terminal transmembrane sequences
-
M. Chen J.T. Zhang 1999 Topogenesis of cystic fibrosis transmembrane conductance regulator (CFTR): regulation by the amino terminal transmembrane sequences Biochemistry 38 5471 5477
-
(1999)
Biochemistry
, vol.38
, pp. 5471-5477
-
-
Chen, M.1
Zhang, J.T.2
-
15
-
-
0027985063
-
Secretory proteins move through the endoplasmic reticulum membrane via an aqueous, gated pore
-
K.S. Crowley S. Liao V.E. Worrell G.D. Reinhart A.E. Johnson 1994 Secretory proteins move through the endoplasmic reticulum membrane via an aqueous, gated pore Cell 78 461 471
-
(1994)
Cell
, vol.78
, pp. 461-471
-
-
Crowley, K.S.1
Liao, S.2
Worrell, V.E.3
Reinhart, G.D.4
Johnson, A.E.5
-
16
-
-
0027162564
-
The signal sequence moves through a ribosomal tunnel into a noncytoplasmic aqueous environment at the ER membrane early in translocation
-
K. Crowley G. Reinhart A. Johnson 1993 The signal sequence moves through a ribosomal tunnel into a noncytoplasmic aqueous environment at the ER membrane early in translocation Cell 73 1101 1115
-
(1993)
Cell
, vol.73
, pp. 1101-1115
-
-
Crowley, K.1
Reinhart, G.2
Johnson, A.3
-
17
-
-
0029561894
-
Transmembrane orientation of signal-anchor proteins is affected by the folding state but not the size of the N-terminal domain
-
A. Denzer C. Nabholz M. Spiess 1995 Transmembrane orientation of signal-anchor proteins is affected by the folding state but not the size of the N-terminal domain EMBO J. 14 6311 6317
-
(1995)
EMBO J.
, vol.14
, pp. 6311-6317
-
-
Denzer, A.1
Nabholz, C.2
Spiess, M.3
-
18
-
-
0342995731
-
The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process
-
H. Do D. Falcone J. Lin D.W. Andrews A.E. Johnson 1996 The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process Cell 85 369 378
-
(1996)
Cell
, vol.85
, pp. 369-378
-
-
Do, H.1
Falcone, D.2
Lin, J.3
Andrews, D.W.4
Johnson, A.E.5
-
19
-
-
0029128068
-
Membrane insertion and assembly of ductin: A polytopic channel with dual orientations
-
J. Dunlop P.C. Jones M.E. Finbow 1995 Membrane insertion and assembly of ductin: a polytopic channel with dual orientations EMBO J. 14 3609 3616
-
(1995)
EMBO J.
, vol.14
, pp. 3609-3616
-
-
Dunlop, J.1
Jones, P.C.2
Finbow, M.E.3
-
20
-
-
0037450802
-
Substrate-specific function of the translocon-associated protein complex during translocation across the ER membrane
-
R.D. Fons B.A. Bogert R.S. Hegde 2003 Substrate-specific function of the translocon-associated protein complex during translocation across the ER membrane J. Cell Biol. 160 529 539
-
(2003)
J. Cell Biol.
, vol.160
, pp. 529-539
-
-
Fons, R.D.1
Bogert, B.A.2
Hegde, R.S.3
-
21
-
-
0034602391
-
Identification of sequence determinants that direct different intracellular folding pathways for aquaporin-1 and aquaporin-4
-
A. Helm W. Foster I. Turnbull H. Gulati B. Yang A.S. Verkman W.R. Skach 2000 Identification of sequence determinants that direct different intracellular folding pathways for aquaporin-1 and aquaporin-4 J. Biol. Chem. 275 34157 34165
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34157-34165
-
-
Helm, A.1
Foster, W.2
Turnbull, I.3
Gulati, H.4
Yang, B.5
Verkman, A.S.6
Skach, W.R.7
-
22
-
-
0028175016
-
Topological 'frustration' in multispanning E. coli inner membrane proteins
-
G. Gafvelin G. von Heijne 1994 Topological 'frustration' in multispanning E. coli inner membrane proteins Cell 77 401 402
-
(1994)
Cell
, vol.77
, pp. 401-402
-
-
Gafvelin, G.1
Von Heijne, G.2
-
23
-
-
1542313960
-
Sec61p contributes to signal sequence orientation according to the positive inside rule
-
V. Goder T. Junne M. Spiess 2004 Sec61p contributes to signal sequence orientation according to the positive inside rule Mol. Biol. Cell 15 1470 1478
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 1470-1478
-
-
Goder, V.1
Junne, T.2
Spiess, M.3
-
24
-
-
0035979713
-
Topogenesis of membrane proetins: Determinants and dynamics
-
V. Goder M. Spiess 2001 Topogenesis of membrane proetins: determinants and dynamics FEES Lett 504 87 93
-
(2001)
FEES Lett
, vol.504
, pp. 87-93
-
-
Goder, V.1
Spiess, M.2
-
25
-
-
0026504192
-
A protein of the endoplasmic reticulum involved early in polypeptide translocation
-
D. Gorlich E. Hartmann S. Prehn T.A. Rapoport 1992 A protein of the endoplasmic reticulum involved early in polypeptide translocation. [see comment] Nature 357 47 52
-
(1992)
Nature
, vol.357
, pp. 47-52
-
-
Gorlich, D.1
Hartmann, E.2
Prehn, S.3
Rapoport, T.A.4
-
26
-
-
0027424601
-
Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane, [see comment]
-
D. Gorlich T.A. Rapoport 1993 Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane, [see comment] Cell 75 615 630
-
(1993)
Cell
, vol.75
, pp. 615-630
-
-
Gorlich, D.1
Rapoport, T.A.2
-
27
-
-
0037148535
-
A new role for BiP: Closing the aqueous translocon pore during protein integration into the ER membrane
-
N.G. Haigh A.E. Johnson 2002 A new role for BiP: closing the aqueous translocon pore during protein integration into the ER membrane J. Cell Biol. 156 261 270
-
(2002)
J. Cell Biol.
, vol.156
, pp. 261-270
-
-
Haigh, N.G.1
Johnson, A.E.2
-
28
-
-
0030611388
-
The aqueous pore through the translocon has a diameter of 40-60 Å during cotranslational protein translocation at the ER membrane
-
B.D. Hamman J.C. Chen E. Johnson A.E. Johnson 1997 The aqueous pore through the translocon has a diameter of 40-60 Å during cotranslational protein translocation at the ER membrane Cell 89 535 544
-
(1997)
Cell
, vol.89
, pp. 535-544
-
-
Hamman, B.D.1
Chen, J.C.2
Johnson, E.3
Johnson, A.E.4
-
29
-
-
0032549767
-
BiP maintains the permeability barrier of the ER membrane by sealing the lumenal end of the translocon pore before and early in translocation
-
B.D. Hamman L.M. Hendershot A.E. Johnson 1998 BiP maintains the permeability barrier of the ER membrane by sealing the lumenal end of the translocon pore before and early in translocation Cell 92 747 758
-
(1998)
Cell
, vol.92
, pp. 747-758
-
-
Hamman, B.D.1
Hendershot, L.M.2
Johnson, A.E.3
-
30
-
-
0034435098
-
A novel CFTR disease-associated mutation causes addition of an extra N-linked oligosaccharide
-
M. Hammerle A. Aleksandrov X.B. Chang J.R. Riordan 2000 A novel CFTR disease-associated mutation causes addition of an extra N-linked oligosaccharide Glycoconjugate J. 17 807 813
-
(2000)
Glycoconjugate J.
, vol.17
, pp. 807-813
-
-
Hammerle, M.1
Aleksandrov, A.2
Chang, X.B.3
Riordan, J.R.4
-
32
-
-
0030782178
-
Membrane protein biogenesis: Regulated complexity at the endoplasmic reticulum
-
R.S. Hegde V.R. Lingappa 1997 Membrane protein biogenesis: regulated complexity at the endoplasmic reticulum Cell 91 575 582
-
(1997)
Cell
, vol.91
, pp. 575-582
-
-
Hegde, R.S.1
Lingappa, V.R.2
-
33
-
-
0032488777
-
A transmembrane form of the prion protein in neurodegenerative disease
-
R.S. Hegde J.A. Mastrianni M.R. Scott K.A. Defea P. Tremblay M. Torchia S.J. Dearmond S.B. Prusiner V.R. Lingappa 1998a A transmembrane form of the prion protein in neurodegenerative disease Science 279 827 834
-
(1998)
Science
, vol.279
, pp. 827-834
-
-
Hegde, R.S.1
Mastrianni, J.A.2
Scott, M.R.3
Defea, K.A.4
Tremblay, P.5
Torchia, M.6
Dearmond, S.J.7
Prusiner, S.B.8
Lingappa, V.R.9
-
34
-
-
0032113448
-
Regulation of protein topology by trans-acting factors at the endoplasmic reticulum
-
R.S. Hegde S. Voigt V.R. Lingappa 1998b Regulation of protein topology by trans-acting factors at the endoplasmic reticulum Mol. Cell 2 85 91
-
(1998)
Mol. Cell
, vol.2
, pp. 85-91
-
-
Hegde, R.S.1
Voigt, S.2
Lingappa, V.R.3
-
35
-
-
0032489505
-
TRAM regulates the exposure of nascent secretory proteins to the cytosol during translocation into the endoplasmic reticulum
-
R.S. Hegde S. Voigt T.A. Rapoport V.R. Lingappa 1998c TRAM regulates the exposure of nascent secretory proteins to the cytosol during translocation into the endoplasmic reticulum Cell 92 621 631
-
(1998)
Cell
, vol.92
, pp. 621-631
-
-
Hegde, R.S.1
Voigt, S.2
Rapoport, T.A.3
Lingappa, V.R.4
-
36
-
-
0034697967
-
The Sec61p complex mediates the integration of a membrane protein by allowing lipid partitioning of the transmembrane domain
-
S.U. Heinrich W. Mothes J. Brunner T.A. Rapoport 2000 The Sec61p complex mediates the integration of a membrane protein by allowing lipid partitioning of the transmembrane domain Cell 102 233 244
-
(2000)
Cell
, vol.102
, pp. 233-244
-
-
Heinrich, S.U.1
Mothes, W.2
Brunner, J.3
Rapoport, T.A.4
-
37
-
-
0042815085
-
Cooperation of transmembrane segments during the integration of a double-spanning protein into the ER membrane
-
S.U. Heinrich T.A. Rapoport 2003 Cooperation of transmembrane segments during the integration of a double-spanning protein into the ER membrane EMBO J. 22 3654 3663
-
(2003)
EMBO J.
, vol.22
, pp. 3654-3663
-
-
Heinrich, S.U.1
Rapoport, T.A.2
-
38
-
-
0027454264
-
Site-specific photocross-linking reveals that Sec61p and TRAM contact different regions of a membrane-inserted signal sequence
-
S. High B. Martoglio D. Golrich S.S. Andersen A.J. Ashfore A.E. Giner E. Hartmann S. Prehn T.A. Rapoport B. Dobberstein 1993 Site-specific photocross-linking reveals that Sec61p and TRAM contact different regions of a membrane-inserted signal sequence J. Biol. Chem. 268 26745 26751
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 26745-26751
-
-
High, S.1
Martoglio, B.2
Golrich, D.3
Andersen, S.S.4
Ashfore, A.J.5
Giner, A.E.6
Hartmann, E.7
Prehn, S.8
Rapoport, T.A.9
Dobberstein, B.10
-
40
-
-
0029096050
-
A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane
-
B. Jungnickel T.A. Rapoport 1995 A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane. [see comment] Cell 82 261 2170
-
(1995)
Cell
, vol.82
, pp. 261-2170
-
-
Jungnickel, B.1
Rapoport, T.A.2
-
41
-
-
0037129978
-
The amino terminus of opsin translocates 'posttranslationally' as efficiently as cotranslationally
-
E.M. Kanner I.K. Klein M. Friedlander S.M. Simon 2002 The amino terminus of opsin translocates 'posttranslationally' as efficiently as cotranslationally Biochemistry 41 7707 7715
-
(2002)
Biochemistry
, vol.41
, pp. 7707-7715
-
-
Kanner, E.M.1
Klein, I.K.2
Friedlander, M.3
Simon, S.M.4
-
43
-
-
0031030059
-
Discrete cross-linking products identified during membrane protein biosynthesis
-
V. Laird S. High 1997 Discrete cross-linking products identified during membrane protein biosynthesis J. Biol. Chem. 72 1983 1989
-
(1997)
J. Biol. Chem.
, vol.72
, pp. 1983-1989
-
-
Laird, V.1
High, S.2
-
44
-
-
0031471055
-
Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration
-
S. Liao J. Lin H. Do A.E. Johnson 1997 Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration. [comment] Cell 90 31 41
-
(1997)
Cell
, vol.90
, pp. 31-41
-
-
Liao, S.1
Lin, J.2
Do, H.3
Johnson, A.E.4
-
46
-
-
0023681547
-
Signal and membrane anchor functions overlap in the type II membrane protein I gamma CAT
-
J. Lipp B. Dobberstein 1988 Signal and membrane anchor functions overlap in the type II membrane protein I gamma CAT J. Cell Biol. 106 1813 1820
-
(1988)
J. Cell Biol.
, vol.106
, pp. 1813-1820
-
-
Lipp, J.1
Dobberstein, B.2
-
47
-
-
0024454463
-
Structural requirements for membrane assembly of proteins spanning the membrane several times
-
J. Lipp N. Flint M.T. Haeuptle B. Dobberstein 1989 Structural requirements for membrane assembly of proteins spanning the membrane several times J. Cell Biol. 109 2013 2022
-
(1989)
J. Cell Biol.
, vol.109
, pp. 2013-2022
-
-
Lipp, J.1
Flint, N.2
Haeuptle, M.T.3
Dobberstein, B.4
-
48
-
-
0032700184
-
Determining the structure and mechanism of the human multidrug resistance P-glycoprotein using cysteine-scanning mutagenesis and thiol-modification techniques
-
T.W. Loo D.M. Clarke 1999 Determining the structure and mechanism of the human multidrug resistance P-glycoprotein using cysteine-scanning mutagenesis and thiol-modification techniques Biochim. Biophys. Acta 1461 315 325
-
(1999)
Biochim. Biophys. Acta
, vol.1461
, pp. 315-325
-
-
Loo, T.W.1
Clarke, D.M.2
-
49
-
-
0031983038
-
Co- and posttranslational translocation mechanisms direct cystic fibrosis transmembrane conductance regulator N terminus transmembrane assembly
-
Y. Lu X. Xiong A. Helm K. Kimani A. Bragin W.R. Skach 1998 Co- and posttranslational translocation mechanisms direct cystic fibrosis transmembrane conductance regulator N terminus transmembrane assembly J. Biol. Chem. 273 568 576
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 568-576
-
-
Lu, Y.1
Xiong, X.2
Helm, A.3
Kimani, K.4
Bragin, A.5
Skach, W.R.6
-
50
-
-
0029002962
-
The protein-conducting channel in the membrane of the endoplasmic reticulum is open laterally toward the lipid bilayer
-
B. Martoglio M.W. Hofmann J. Brunner B. Dobberstein 1995 The protein-conducting channel in the membrane of the endoplasmic reticulum is open laterally toward the lipid bilayer Cell 81 207 214
-
(1995)
Cell
, vol.81
, pp. 207-214
-
-
Martoglio, B.1
Hofmann, M.W.2
Brunner, J.3
Dobberstein, B.4
-
51
-
-
0141992130
-
Cotranslational protein integration into the ER membrane is mediated by the binding of nascent chains to translocon proteins
-
P.J. McCormick Y. Miao Y. Shao J. Lin A.E. Johnson 2003 Cotranslational protein integration into the ER membrane is mediated by the binding of nascent chains to translocon proteins Mol. Cell 12 329 341
-
(2003)
Mol. Cell
, vol.12
, pp. 329-341
-
-
McCormick, P.J.1
Miao, Y.2
Shao, Y.3
Lin, J.4
Johnson, A.E.5
-
52
-
-
0036906637
-
Different transmembrane domains associate with distinct endoplasmic reticulum components during membrane integration of a polytopic protein
-
S.L. Meacock F.J. Lecomte S.G. Crawshaw S. High 2002 Different transmembrane domains associate with distinct endoplasmic reticulum components during membrane integration of a polytopic protein Mol. Biol. Cell 13 4114 4129
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 4114-4129
-
-
Meacock, S.L.1
Lecomte, F.J.2
Crawshaw, S.G.3
High, S.4
-
55
-
-
0031686961
-
Coupled translocation events generate topological heterogeneity at the endoplasmic reticulum membrane
-
K. Moss A. Helm Y. Lu A. Bragin W.R. Skach 1998 Coupled translocation events generate topological heterogeneity at the endoplasmic reticulum membrane Mol. Biol. Cell 9 2681 2697
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 2681-2697
-
-
Moss, K.1
Helm, A.2
Lu, Y.3
Bragin, A.4
Skach, W.R.5
-
57
-
-
0027417476
-
Determination of the distance between the oligosaccharyltransferase active site and the endoplasmic reticulum membrane
-
I.M. Nilsson G. von Heijne 1993 Determination of the distance between the oligosaccharyltransferase active site and the endoplasmic reticulum membrane J. Biol. Chem. 268 5798 5801
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 5798-5801
-
-
Nilsson, I.M.1
Von Heijne, G.2
-
58
-
-
0032561457
-
Assessment of topogenic functions of anticipated transmembrane segments of human band 3
-
K. Ota M. Sakaguchi N. Hamasaki K. Mihara 1998 Assessment of topogenic functions of anticipated transmembrane segments of human band 3 J. Biol. Chem. 273 28286 28291
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 28286-28291
-
-
Ota, K.1
Sakaguchi, M.2
Hamasaki, N.3
Mihara, K.4
-
59
-
-
0034703018
-
Membrane integration of the second transmembrane segment of band 3 requires a closely apposed preceding signal-anchor sequence
-
K. Ota M. Sakaguchi N. Hamasaki K. Mihara 2000 Membrane integration of the second transmembrane segment of band 3 requires a closely apposed preceding signal-anchor sequence J. Biol. Chem. 275 29743 29748
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 29743-29748
-
-
Ota, K.1
Sakaguchi, M.2
Hamasaki, N.3
Mihara, K.4
-
60
-
-
0022550043
-
Uncoupling translocation from translation: Implications for transport of proteins across membranes
-
E. Perara R. Rothman V.R. Lingappa 1986 Uncoupling translocation from translation: implications for transport of proteins across membranes Science 232 348 352
-
(1986)
Science
, vol.232
, pp. 348-352
-
-
Perara, E.1
Rothman, R.2
Lingappa, V.R.3
-
61
-
-
0032544614
-
Signal sequence recognition in posttranslational protein transport across the yeast ER membrane
-
E. Plath W. Mothes B.M. Wilkinson C.J. Stirling T.A. Rapoport 1998 Signal sequence recognition in posttranslational protein transport across the yeast ER membrane Cell 94 795 807
-
(1998)
Cell
, vol.94
, pp. 795-807
-
-
Plath, E.1
Mothes, W.2
Wilkinson, B.M.3
Stirling, C.J.4
Rapoport, T.A.5
-
62
-
-
0033790343
-
Helical membrane protein folding, stability and evolution
-
J. Popot D. Engelman 2000 Helical membrane protein folding, stability and evolution Ann. Rev. Biochem. 69 881 922
-
(2000)
Ann. Rev. Biochem.
, vol.69
, pp. 881-922
-
-
Popot, J.1
Engelman, D.2
-
63
-
-
0030745799
-
Mapping the ends of transmembrane segments in a polytopic membrane protein. Scanning N-glycosylation mutagenesis of extracytosolic loops in the anion exchanger, band 3
-
M. Popov L.Y. Tam J. Li R.A. Reithmeier 1997 Mapping the ends of transmembrane segments in a polytopic membrane protein. Scanning N-glycosylation mutagenesis of extracytosolic loops in the anion exchanger, band 3 J. Biol. Chem. 272 18325 18332
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18325-18332
-
-
Popov, M.1
Tam, L.Y.2
Li, J.3
Reithmeier, R.A.4
-
64
-
-
0025217112
-
Structure and biosynthesis of the signal-sequence receptor
-
S. Prehn J. Herz E. Hartmann T.V. Kurzchalia R. Frank K. Roemisch B. Dobberstein T.A. Rapoport 1990 Structure and biosynthesis of the signal-sequence receptor Eur. J. Biochem. 188 439 445
-
(1990)
Eur. J. Biochem.
, vol.188
, pp. 439-445
-
-
Prehn, S.1
Herz, J.2
Hartmann, E.3
Kurzchalia, T.V.4
Frank, R.5
Roemisch, K.6
Dobberstein, B.7
Rapoport, T.A.8
-
65
-
-
0030678106
-
Empty site forms of the SRP54 and SR alpha GTPases mediate targeting of ribosome-nascent chain complexes to the endoplasmic reticulum.[see comment]
-
P.J. Rapiejko R. Gilmore 1997 Empty site forms of the SRP54 and SR alpha GTPases mediate targeting of ribosome-nascent chain complexes to the endoplasmic reticulum.[see comment] Cell 89 703 713
-
(1997)
Cell
, vol.89
, pp. 703-713
-
-
Rapiejko, P.J.1
Gilmore, R.2
-
66
-
-
0024424270
-
Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA.[erratum appears in Science 1989;245:1437]
-
J.R. Riordan J.M. Rommens B. Kerem N. Alon R. Rozmahel Z. Grzelczak J. Zielenski S. Lok N. Plavsic J.L. Chou 1989 Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.[erratum appears in Science 1989;245:1437] Science 245 1066 1073
-
(1989)
Science
, vol.245
, pp. 1066-1073
-
-
Riordan, J.R.1
Rommens, J.M.2
Kerem, B.3
Alon, N.4
Rozmahel, R.5
Grzelczak, Z.6
Zielenski, J.7
Lok, S.8
Plavsic, N.9
Chou, J.L.10
-
68
-
-
0026501551
-
Functions of signal and signal-anchor sequences are determined by the balance between the hydrophobic segment and N-terminal charge
-
M. Sakaguchi R. Tomiyoshi T. Kuroiowa K. Mihara T. Omura 1992 Functions of signal and signal-anchor sequences are determined by the balance between the hydrophobic segment and N-terminal charge Proc. Natl. Acad. Sci. USA 89 16 19
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 16-19
-
-
Sakaguchi, M.1
Tomiyoshi, R.2
Kuroiowa, T.3
Mihara, K.4
Omura, T.5
-
69
-
-
0037459073
-
Protein translocons: Multifunctional mediators of protein translocation across membranes
-
D. Schnell D. Hebert 2003 Protein translocons: multifunctional mediators of protein translocation across membranes Cell 112 491 505
-
(2003)
Cell
, vol.112
, pp. 491-505
-
-
Schnell, D.1
Hebert, D.2
-
70
-
-
0039677397
-
Control of glycosylation of MHC class II-associated invariant chain by translocon-associated RAMP4.[erratum appears in EMBO J. 2002,21:6954]
-
K. Schroder B. Martoglio M. Hofmann C. Holscher E. Hartmann S. Prehn T.A. Rapoport B. Dobberstein 1999 Control of glycosylation of MHC class II-associated invariant chain by translocon-associated RAMP4.[erratum appears in EMBO J. 2002,21:6954] EMBO J 18 4804 4815
-
(1999)
EMBO J
, vol.18
, pp. 4804-4815
-
-
Schroder, K.1
Martoglio, B.2
Hofmann, M.3
Holscher, C.4
Hartmann, E.5
Prehn, S.6
Rapoport, T.A.7
Dobberstein, B.8
-
71
-
-
0027512232
-
Evidence for an alternate model of human P-glyocprotein structure and biogenesis
-
W.R. Skach M.C. Calayag V.R. Lingappa 1993 Evidence for an alternate model of human P-glyocprotein structure and biogenesis J. Biol. Chem. 268 6903 6908
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 6903-6908
-
-
Skach, W.R.1
Calayag, M.C.2
Lingappa, V.R.3
-
72
-
-
0027519416
-
Amino-terminal assembly of human P-glycoprotein at the endoplasmic reticulum is directed by cooperative actions of two internal sequences
-
W.R. Skach V.R. Lingappa 1993 Amino-terminal assembly of human P-glycoprotein at the endoplasmic reticulum is directed by cooperative actions of two internal sequences J. Biol. Chem. 268 23552 23561
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 23552-23561
-
-
Skach, W.R.1
Lingappa, V.R.2
-
73
-
-
0028343114
-
Transmembrane orientation and topogenesis of the third and fourth membrane-spanning regions of human P-glycoprotein (MDR1)
-
W.R. Skach V.R. Lingappa 1994 Transmembrane orientation and topogenesis of the third and fourth membrane-spanning regions of human P-glycoprotein (MDR1) Cancer Res 54 3202 3209
-
(1994)
Cancer Res
, vol.54
, pp. 3202-3209
-
-
Skach, W.R.1
Lingappa, V.R.2
-
75
-
-
0034602866
-
Role of Sec61alpha in the regulated transfer of the ribosome-nascent chain complex from the signal recognition particle to the translocation channel
-
W. Song D. Raden E.C. Mandon R. Gilmore 2000 Role of Sec61alpha in the regulated transfer of the ribosome-nascent chain complex from the signal recognition particle to the translocation channel Cell 100 333 343
-
(2000)
Cell
, vol.100
, pp. 333-343
-
-
Song, W.1
Raden, D.2
Mandon, E.C.3
Gilmore, R.4
-
76
-
-
0029149453
-
Heads or tails-what determines the orientation of proteins in the membrane
-
M. Spiess 1995 Heads or tails-what determines the orientation of proteins in the membrane FEBS Lett 369 76 79
-
(1995)
FEBS Lett
, vol.369
, pp. 76-79
-
-
Spiess, M.1
-
77
-
-
0033570916
-
An unstable transmembrane segment in the cystic fibrosis transmembrane conductance regulator
-
M.F.U. Tector Hartl 1999 An unstable transmembrane segment in the cystic fibrosis transmembrane conductance regulator EMBO J. 18 6290 6298
-
(1999)
EMBO J.
, vol.18
, pp. 6290-6298
-
-
Tector Hartl, M.F.U.1
-
78
-
-
0026061020
-
A nascent membrane protein is located adjacent to ER membrane proteins throughout its integration and translation
-
R.N. Thrift D.W. Andrews P. Walter A.E. Johnson 1991 A nascent membrane protein is located adjacent to ER membrane proteins throughout its integration and translation J. Cell Biol. 112 809 821
-
(1991)
J. Cell Biol.
, vol.112
, pp. 809-821
-
-
Thrift, R.N.1
Andrews, D.W.2
Walter, P.3
Johnson, A.E.4
-
81
-
-
0029951178
-
Signal sequence-dependent function of the TRAM protein during early phases of protein transport across the endoplasmic reticulum membrane
-
S. Voigt B. Jungnickel E. Hartmann T.A. Rapoport 1996 Signal sequence-dependent function of the TRAM protein during early phases of protein transport across the endoplasmic reticulum membrane J. Cell Biol. 134 25 35
-
(1996)
J. Cell Biol.
, vol.134
, pp. 25-35
-
-
Voigt, S.1
Jungnickel, B.2
Hartmann, E.3
Rapoport, T.A.4
-
82
-
-
0000651660
-
The distribution of positively charged residues in bacterial inner membrane proteins correlates with trans-membrane topology
-
G. von Heijne 1986 The distribution of positively charged residues in bacterial inner membrane proteins correlates with trans-membrane topology EMBO J. 5 3021 3027
-
(1986)
EMBO J.
, vol.5
, pp. 3021-3027
-
-
Von Heijne, G.1
-
83
-
-
0019817924
-
Translocation of proteins across the endoplasmic reticulum. II. Signal recognition protein (SRP) mediates the selective binding to microsomal membranes of in-vitro-assembled polysomes synthesizing secretory protein
-
P. Walter G. Blobel 1981 Translocation of proteins across the endoplasmic reticulum. II. Signal recognition protein (SRP) mediates the selective binding to microsomal membranes of in-vitro-assembled polysomes synthesizing secretory protein J. Cell Biol. 91 551 556
-
(1981)
J. Cell Biol.
, vol.91
, pp. 551-556
-
-
Walter, P.1
Blobel, G.2
-
84
-
-
0032832467
-
Oligomeric complexes involved in translocation of proteins across the membrane of the endoplasmic reticulum
-
L. Wang B. Dobberstein 1999 Oligomeric complexes involved in translocation of proteins across the membrane of the endoplasmic reticulum FEES Lett. 457 316 322
-
(1999)
FEES Lett.
, vol.457
, pp. 316-322
-
-
Wang, L.1
Dobberstein, B.2
-
85
-
-
0242488929
-
Translocons, thermodynamics, and the folding of membrane proteins
-
S.H. White 2003 Translocons, thermodynamics, and the folding of membrane proteins FEBS Lett. 555 116 121
-
(2003)
FEBS Lett.
, vol.555
, pp. 116-121
-
-
White, S.H.1
-
86
-
-
1542358892
-
Nascent membrane and secretory proteins differ in FRET-detected folding far inside the ribosome and in their exposure to ribosomal proteins
-
C.A. Woolhead P.A. McCormick A.E. Johnson 2004 Nascent membrane and secretory proteins differ in FRET-detected folding far inside the ribosome and in their exposure to ribosomal proteins Cell 116 725 736
-
(2004)
Cell
, vol.116
, pp. 725-736
-
-
Woolhead, C.A.1
McCormick, P.A.2
Johnson, A.E.3
-
87
-
-
0030029807
-
Only the first and the last hydrophobic segments in the COOH-terminal third of Na,K-ATPase alpha subunit initiate and halt, respectively, membrane translocation of the newly synthesized polypeptide. Implications for the membrane topology
-
Y. Xie S.A. Langhans-Rajasekaran D. Bellovino T. Morimoto 1996 Only the first and the last hydrophobic segments in the COOH-terminal third of Na,K-ATPase alpha subunit initiate and halt, respectively, membrane translocation of the newly synthesized polypeptide. Implications for the membrane topology J. Biol. Chem. 271 2563 2573
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2563-2573
-
-
Xie, Y.1
Langhans-Rajasekaran, S.A.2
Bellovino, D.3
Morimoto, T.4
-
88
-
-
0030931382
-
Structural cues involved in endoplasmic reticulum degradation of G85E and G91R mutant cystic fibrosis transmembrane conductance regulator
-
X. Xiong A. Bragin J.H. Widdicombe J. Cohn W.R. Skach 1997 Structural cues involved in endoplasmic reticulum degradation of G85E and G91R mutant cystic fibrosis transmembrane conductance regulator J. Clin. Invest. 100 1079 1088
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 1079-1088
-
-
Xiong, X.1
Bragin, A.2
Widdicombe, J.H.3
Cohn, J.4
Skach, W.R.5
-
89
-
-
0031946150
-
Dissection of de novo membrane insertion activities of internal transmembrane segments of ATP-binding-cassette transporters: Toward understanding topological rules for membrane assembly of polytopic membrane proteins
-
J.T. Zhang M. Chen E. Han C. Wang 1998 Dissection of de novo membrane insertion activities of internal transmembrane segments of ATP-binding-cassette transporters: toward understanding topological rules for membrane assembly of polytopic membrane proteins Mol. Biol. Cell 9 853 863
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 853-863
-
-
Zhang, J.T.1
Chen, M.2
Han, E.3
Wang, C.4
-
90
-
-
0025951859
-
Study of membrane orientation and glycosylated extracellular loops of mouse P-glycoprotein by in vitro translation
-
J.T. Zhang V. Ling 1991 Study of membrane orientation and glycosylated extracellular loops of mouse P-glycoprotein by in vitro translation J. Biol. Chem. 266 18224 18232
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 18224-18232
-
-
Zhang, J.T.1
Ling, V.2
|