Interhelical hydrogen bonds and spatial motifs in membrane proteins: Polar clamps and serine zippers

Proteins: Structure, Function and Genetics

Volumn 47, Issue 2, 2002, Pages 209-218

  Adamian, Larisa ^a   Liang, Jie ^a  

^a University of Illinois at Chicago   (United States)

Author keywords

Alpha shape; Helical packing; Hydrogen bonds; Membrane protein; Spatial motifs

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CYTOCHROME C OXIDASE; HALORHODOPSIN; MEMBRANE PROTEIN;

ARTICLE; CATTLE; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACID MOTIFS; AMINO ACIDS; ANIMALS; CALCIUM-TRANSPORTING ATPASES; CATTLE; ELECTRON TRANSPORT COMPLEX IV; HALORHODOPSINS; HYDROGEN BONDING; MEMBRANE PROTEINS; MODELS, MOLECULAR; PROTEIN STRUCTURE, SECONDARY; SERINE;

BOVINAE;

EID: 0036568229     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.10071     Document Type: Article

References (44)

1. Statistical analysis of predicted transmembrane α-helices
2. Statistical analysis of amino acid patterns in transmembrane helices: The GxxxG motif occurs frequently and in association with β-branched residues at neighboring positions
3. Membrane protein folding and stability: Physical principles
4. Structure of bacteriorhodopsin at 1.55 A resolution
5. Structure of a glycerol-conducting channel and the basis for its selectivity
6. Structure of light-driven chloride pump halorhodopsin at 1.8 A resolution
7. Crystal structure of rhodopsin: A G protein-coupled receptor
8. Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 A resolution
9. Asparagine-mediated self-association of a model transmembrane helix
10. Interhelical hydrogen bonding drives strong interactions in membrane proteins
11. a-H...O hydrogen bond: A determinant of stability and specificity in transmembrane helix interactions
12. Polar side chains drive the association of model transmembrane peptides
13. The change in hydrogen bond strength accompanying charge rearrangement: Implications for enzymatic catalysis
14. Structure and mechanism of the aberrant ba(3)-cytochrome c oxidase from Thermus thermophilus
15. Structure of the E. coli fumarate reductase respiratory complex
16. Structure of fumarate reductase from wolinella succinogenes at 2.2 A resolution
17. The effect of point mutations on the free energy of transmembrane alpha-helix dimerization
18. Helix packing in polytopic membrane proteins: Role of glycine in transmembrane helix association
19. Helix-helix packing and interfacial pair-wise interactions of residues in membrane proteins
20. Structure at 2.7 A resolution of the Paracoccus denitrificans two-subunit cytochrome c oxidase complexed with an antibody FV fragment
21. Redoxcoupled crystal structural changes in bovine heart cytochrome c oxidase
22. 3-Dimensional alpha-shapes
23. Incremental topological flipping works for regular triangulations
24. Implementation of a randomized algorithm for Delaunay and regular triangulation in 3 dimensions
25. The packing density in proteins: Standard radii and volumes
26. Satisfying hydrogen bonding potential in proteins
27. A transmembrane helix dimer: Structure and implications
28. Coiled coils: New structures and new functions
29. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
30. Sequence Logos A new way to display consensus sequences
31. Dominat forces in protein folding
32. 2+-ATPases
33. Short and long range functions of amino acids in the transmembrane region of the sarcoplasmic reticulum ATPase
34. CLUSTAL: A package for performing multiple sequence alignment on a microcomputer
35. Chemical reconstitution of a chloride pump inactivated by a single point mutation
36. Interhelical hydrogen bonds in the CFTR membrane domain
37. Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185
38. Strong hydrogen bonding interactions involving a buried glutamic acid in the transmembrane sequence of the neu/erbB-2 receptor
39. Role of helix-helix interaction in the assembly of the bacteriorhodopsin lattice
40. Refolding of bacteriorhodopsin from expressed polypeptide fragments
41. Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex
42. The structure of the potassium channel: Molecular basis of K+ conduction and selectivity
43. MOLMOL: A program for display and analysis of macromolecular structures