-
2
-
-
0024226701
-
Metabolic zonation of liver parenchyma
-
K. Jungermann Metabolic zonation of liver parenchyma Semin. Liver Dis. 8 1988 329 341
-
(1988)
Semin. Liver Dis.
, vol.8
, pp. 329-341
-
-
Jungermann, K.1
-
3
-
-
0026550172
-
Role of intralobular compartmentation in hepatic metabolism
-
K. Jungermann Role of intralobular compartmentation in hepatic metabolism Diabete Metab. 18 1992 81 86
-
(1992)
Diabete Metab.
, vol.18
, pp. 81-86
-
-
Jungermann, K.1
-
4
-
-
0024336445
-
Functional specialization of different hepatocyte populations
-
K. Jungermann, and N. Katz Functional specialization of different hepatocyte populations Physiol. Rev. 69 1989 708 764
-
(1989)
Physiol. Rev.
, vol.69
, pp. 708-764
-
-
Jungermann, K.1
Katz, N.2
-
6
-
-
0023716149
-
Glucagon regulation of gluconeogenesis and ketogenesis in periportal and perivenous rat hepatocytes. Heterogeneity of hormone action and of the mitochondrial redox state
-
D. Tosh, G.M. Alberti, and L. Agius Glucagon regulation of gluconeogenesis and ketogenesis in periportal and perivenous rat hepatocytes. Heterogeneity of hormone action and of the mitochondrial redox state Biochem. J. 256 1988 197 204
-
(1988)
Biochem. J.
, vol.256
, pp. 197-204
-
-
Tosh, D.1
Alberti, G.M.2
Agius, L.3
-
7
-
-
0026766117
-
Metabolic zonation of the liver: Regulation and implications for liver function
-
R. Gebhardt Metabolic zonation of the liver: regulation and implications for liver function Pharmacol. Ther. 53 1992 275 354
-
(1992)
Pharmacol. Ther.
, vol.53
, pp. 275-354
-
-
Gebhardt, R.1
-
8
-
-
0029800090
-
Zonation of parenchymal and nonparenchymal metabolism in liver
-
K. Jungermann, and T. Kietzmann Zonation of parenchymal and nonparenchymal metabolism in liver Annu. Rev. Nutr. 16 1996 179 203
-
(1996)
Annu. Rev. Nutr.
, vol.16
, pp. 179-203
-
-
Jungermann, K.1
Kietzmann, T.2
-
9
-
-
0026589848
-
Metabolic heterogeneity of hepatocytes across the liver acinus
-
N.R. Katz Metabolic heterogeneity of hepatocytes across the liver acinus J. Nutr. 122 1992 843 849
-
(1992)
J. Nutr.
, vol.122
, pp. 843-849
-
-
Katz, N.R.1
-
10
-
-
0000597418
-
Cell heterogeneity within the hepatic lobule of the rat: Staining reactions
-
A.B. Novikoff Cell heterogeneity within the hepatic lobule of the rat: staining reactions J. Histochem. Cytochem. 7 1959 240 244
-
(1959)
J. Histochem. Cytochem.
, vol.7
, pp. 240-244
-
-
Novikoff, A.B.1
-
11
-
-
0014274040
-
A quantitative stereological description of the ultrastructure of normal rat liver parenchymal cells
-
A.V. Loud A quantitative stereological description of the ultrastructure of normal rat liver parenchymal cells J. Cell Biol. 37 1968 27 46
-
(1968)
J. Cell Biol.
, vol.37
, pp. 27-46
-
-
Loud, A.V.1
-
12
-
-
0017807770
-
Stereological analysis of hepatic fine structure in the Fischer 344 rat. Influence of sublobular location and animal age
-
D.L. Schmucker, J.S. Mooney, and A.L. Jones Stereological analysis of hepatic fine structure in the Fischer 344 rat. Influence of sublobular location and animal age J. Cell Biol. 78 1978 319 337
-
(1978)
J. Cell Biol.
, vol.78
, pp. 319-337
-
-
Schmucker, D.L.1
Mooney, J.S.2
Jones, A.L.3
-
13
-
-
0020959327
-
Distribution of enzymes of fatty acid and ketone body metabolism in periportal and perivenous rat-liver tissue
-
N.R. Katz, W. Fischer, and S. Giffhorn Distribution of enzymes of fatty acid and ketone body metabolism in periportal and perivenous rat-liver tissue Eur. J. Biochem. 135 1983 103 107
-
(1983)
Eur. J. Biochem.
, vol.135
, pp. 103-107
-
-
Katz, N.R.1
Fischer, W.2
Giffhorn, S.3
-
14
-
-
0024522944
-
Zonation of hepatic lipogenic enzymes identified by dual-digitonin-pulse perfusion
-
J.L. Evans, B. Quistorff, and L.A. Witters Zonation of hepatic lipogenic enzymes identified by dual-digitonin-pulse perfusion Biochem. J. 259 1989 821 829
-
(1989)
Biochem. J.
, vol.259
, pp. 821-829
-
-
Evans, J.L.1
Quistorff, B.2
Witters, L.A.3
-
15
-
-
0021981814
-
Metabolische Zonierung des Leberparenchyms. Bedeutung für die Regulation des Glucostaten Leber
-
K. Jungermann Metabolische Zonierung des Leberparenchyms. Bedeutung für die Regulation des Glucostaten Leber Naturwissenschaften 72 1985 76 84
-
(1985)
Naturwissenschaften
, vol.72
, pp. 76-84
-
-
Jungermann, K.1
-
16
-
-
0027093850
-
Hepatocyte heterogeneity in the metabolism of fatty acids: Discrepancies on zonation of acetyl-CoA carboxylase
-
B. Quistorff, N. Katz, and L.A. Witters Hepatocyte heterogeneity in the metabolism of fatty acids: discrepancies on zonation of acetyl-CoA carboxylase Enzyme 46 1992 59 71
-
(1992)
Enzyme
, vol.46
, pp. 59-71
-
-
Quistorff, B.1
Katz, N.2
Witters, L.A.3
-
17
-
-
0028985793
-
Zonation of metabolism and gene expression in liver
-
K. Jungermann Zonation of metabolism and gene expression in liver Histochem. Cell Biol. 103 1995 81 91
-
(1995)
Histochem. Cell Biol.
, vol.103
, pp. 81-91
-
-
Jungermann, K.1
-
18
-
-
0026101649
-
Functional hepatocyte heterogeneity in glutamate, aspartate and alpha-ketoglutarate uptake: A histoautoradiographical study
-
B. Stoll, S. McNelly, H.P. Buscher, and D. Häussinger Functional hepatocyte heterogeneity in glutamate, aspartate and alpha-ketoglutarate uptake: a histoautoradiographical study Hepatology 13 1991 247 253
-
(1991)
Hepatology
, vol.13
, pp. 247-253
-
-
Stoll, B.1
McNelly, S.2
Buscher, H.P.3
Häussinger, D.4
-
19
-
-
84904382731
-
Liver zonation: Novel aspects of its regulation and its impact on homeostasis
-
R. Gebhardt, and M. Matz-Soja Liver zonation: novel aspects of its regulation and its impact on homeostasis World J. Gastroenterol. 20 2014 8491 8504
-
(2014)
World J. Gastroenterol.
, vol.20
, pp. 8491-8504
-
-
Gebhardt, R.1
Matz-Soja, M.2
-
20
-
-
73949116718
-
Organ patterning in the adult stage: The role of Wnt/beta-catenin signaling in liver zonation and beyond
-
R. Gebhardt, and A. Hovhannisyan Organ patterning in the adult stage: the role of Wnt/beta-catenin signaling in liver zonation and beyond Dev. Dyn. 239 2010 45 55
-
(2010)
Dev. Dyn.
, vol.239
, pp. 45-55
-
-
Gebhardt, R.1
Hovhannisyan, A.2
-
21
-
-
0023149819
-
Metabolic zonation of liver parenchyma: Significance for the regulation of glycogen metabolism, gluconeogenesis, and glycolysis
-
K. Jungermann Metabolic zonation of liver parenchyma: significance for the regulation of glycogen metabolism, gluconeogenesis, and glycolysis Diabetes Metab. Rev. 3 1987 269 293
-
(1987)
Diabetes Metab. Rev.
, vol.3
, pp. 269-293
-
-
Jungermann, K.1
-
22
-
-
0027080622
-
Hepatocyte heterogeneity in the metabolism of carbohydrates
-
K. Jungermann, and R.G. Thurman Hepatocyte heterogeneity in the metabolism of carbohydrates Enzyme 46 1992 33 58
-
(1992)
Enzyme
, vol.46
, pp. 33-58
-
-
Jungermann, K.1
Thurman, R.G.2
-
23
-
-
0024451784
-
Zonation of fatty acid metabolism in rat liver
-
M. Guzmán, and J. Castro Zonation of fatty acid metabolism in rat liver Biochem. J. 264 1989 107 113
-
(1989)
Biochem. J.
, vol.264
, pp. 107-113
-
-
Guzmán, M.1
Castro, J.2
-
24
-
-
0025708302
-
Hepatic zonation of acetyl-CoA carboxylase activity
-
J.L. Evans, B. Quistorff, and L.A. Witters Hepatic zonation of acetyl-CoA carboxylase activity Biochem. J. 270 1990 665 672
-
(1990)
Biochem. J.
, vol.270
, pp. 665-672
-
-
Evans, J.L.1
Quistorff, B.2
Witters, L.A.3
-
25
-
-
0025076705
-
Hepatic zonation of insulin-stimulated tyrosine phosphorylation
-
A. Bianchi, B. Quistorff, and L.A. Witters Hepatic zonation of insulin-stimulated tyrosine phosphorylation FEBS Lett. 269 1990 435 439
-
(1990)
FEBS Lett.
, vol.269
, pp. 435-439
-
-
Bianchi, A.1
Quistorff, B.2
Witters, L.A.3
-
26
-
-
0026511548
-
Periportal zonation of the cytosolic acetyl-CoA synthetase of male rat liver
-
C.T. Knudsen, L. Immerdal, N. Grunnet, and B. Quistorff Periportal zonation of the cytosolic acetyl-CoA synthetase of male rat liver Eur. J. Biochem. 204 1992 359 362
-
(1992)
Eur. J. Biochem.
, vol.204
, pp. 359-362
-
-
Knudsen, C.T.1
Immerdal, L.2
Grunnet, N.3
Quistorff, B.4
-
27
-
-
0028275189
-
Hepatic 5′-AMP-activated protein kinase: Zonal distribution and relationship to acetyl-CoA carboxylase activity in varying nutritional states
-
L.A. Witters, G. Gao, B.E. Kemp, and B. Quistorff Hepatic 5′-AMP-activated protein kinase: zonal distribution and relationship to acetyl-CoA carboxylase activity in varying nutritional states Arch. Biochem. Biophys. 308 1994 413 419
-
(1994)
Arch. Biochem. Biophys.
, vol.308
, pp. 413-419
-
-
Witters, L.A.1
Gao, G.2
Kemp, B.E.3
Quistorff, B.4
-
28
-
-
0019782204
-
NADP-dependent dehydrogenases in rat liver parenchyma. III. The description of a liponeogenic area on the basis of histochemically demonstrated enzyme activities and the neutral fat content during fasting and refeeding
-
H. Rieder NADP-dependent dehydrogenases in rat liver parenchyma. III. The description of a liponeogenic area on the basis of histochemically demonstrated enzyme activities and the neutral fat content during fasting and refeeding Histochemistry 72 1981 579 615
-
(1981)
Histochemistry
, vol.72
, pp. 579-615
-
-
Rieder, H.1
-
29
-
-
0023248470
-
Acinar distribution of glutathione-dependent detoxifying enzymes. Low glutathione peroxidase activity in perivenous hepatocytes
-
Y. Kera, H.W. Sippel, K.E. Penttilä, and K.O. Lindros Acinar distribution of glutathione-dependent detoxifying enzymes. Low glutathione peroxidase activity in perivenous hepatocytes Biochem. Pharmacol. 36 1987 2003 2006
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 2003-2006
-
-
Kera, Y.1
Sippel, H.W.2
Penttilä, K.E.3
Lindros, K.O.4
-
30
-
-
0033214093
-
Zonation of gluconeogenesis, ketogenesis and intracellular pH in livers from normal and diabetic ketoacidotic rats: Evidence for intralobular redistribution of metabolic events in ketoacidosis
-
S.P. Burns, R.D. Cohen, R.A. Iles, R.A. Bailey, M. Desai, J.P. Germain, and T.C. Going Zonation of gluconeogenesis, ketogenesis and intracellular pH in livers from normal and diabetic ketoacidotic rats: evidence for intralobular redistribution of metabolic events in ketoacidosis Biochem. J. 343 Pt 1 1999 273 280
-
(1999)
Biochem. J.
, vol.343
, Issue.PART 1
, pp. 273-280
-
-
Burns, S.P.1
Cohen, R.D.2
Iles, R.A.3
Bailey, R.A.4
Desai, M.5
Germain, J.P.6
Going, T.C.7
-
31
-
-
84874786444
-
Differential intrahepatic phospholipid zonation in simple steatosis and nonalcoholic steatohepatitis
-
J. Wattacheril, E.H. Seeley, P. Angel, H. Chen, B.P. Bowen, C. Lanciault, R.M. Caprioli, N. Abumrad, and C.R. Flynn Differential intrahepatic phospholipid zonation in simple steatosis and nonalcoholic steatohepatitis PLoS One 8 2013 e57165
-
(2013)
PLoS One
, vol.8
, pp. e57165
-
-
Wattacheril, J.1
Seeley, E.H.2
Angel, P.3
Chen, H.4
Bowen, B.P.5
Lanciault, C.6
Caprioli, R.M.7
Abumrad, N.8
Flynn, C.R.9
-
32
-
-
23944494582
-
Cancer cachexia modifies the zonal distribution of lipid metabolism-related proteins in rat liver
-
M. Kazantzis, and M.C.L. Seelaender Cancer cachexia modifies the zonal distribution of lipid metabolism-related proteins in rat liver Cell Tissue Res. 321 2005 419 427
-
(2005)
Cell Tissue Res.
, vol.321
, pp. 419-427
-
-
Kazantzis, M.1
Seelaender, M.C.L.2
-
33
-
-
84890568045
-
Zonation of glucose and fatty acid metabolism in the liver: Mechanism and metabolic consequences
-
B.S. Hijmans, A. Grefhorst, M.H. Oosterveer, and A.K. Groen Zonation of glucose and fatty acid metabolism in the liver: mechanism and metabolic consequences Biochimie 96 2014 121 129
-
(2014)
Biochimie
, vol.96
, pp. 121-129
-
-
Hijmans, B.S.1
Grefhorst, A.2
Oosterveer, M.H.3
Groen, A.K.4
-
34
-
-
0035168901
-
A new concept of cellular uptake and intracellular trafficking of long-chain fatty acids
-
W. Stremmel, L. Pohl, A. Ring, and T. Herrmann A new concept of cellular uptake and intracellular trafficking of long-chain fatty acids Lipids 36 2001 981 989
-
(2001)
Lipids
, vol.36
, pp. 981-989
-
-
Stremmel, W.1
Pohl, L.2
Ring, A.3
Herrmann, T.4
-
35
-
-
0347065337
-
Decreased hepatic triglyceride accumulation and altered fatty acid uptake in mice with deletion of the liver fatty acid-binding protein gene
-
E.P. Newberry, Y. Xie, S. Kennedy, X. Han, K.K. Buhman, J. Luo, R.W. Gross, and N.O. Davidson Decreased hepatic triglyceride accumulation and altered fatty acid uptake in mice with deletion of the liver fatty acid-binding protein gene J. Biol. Chem. 278 2003 51664 51672
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 51664-51672
-
-
Newberry, E.P.1
Xie, Y.2
Kennedy, S.3
Han, X.4
Buhman, K.K.5
Luo, J.6
Gross, R.W.7
Davidson, N.O.8
-
36
-
-
33645994508
-
Targeted deletion of FATP5 reveals multiple functions in liver metabolism: Alterations in hepatic lipid homeostasis
-
H. Doege, R.A. Baillie, A.M. Ortegon, B. Tsang, Q. Wu, S. Punreddy, D. Hirsch, N. Watson, R.E. Gimeno, and A. Stahl Targeted deletion of FATP5 reveals multiple functions in liver metabolism: alterations in hepatic lipid homeostasis Gastroenterology 130 2006 1245 1258
-
(2006)
Gastroenterology
, vol.130
, pp. 1245-1258
-
-
Doege, H.1
Baillie, R.A.2
Ortegon, A.M.3
Tsang, B.4
Wu, Q.5
Punreddy, S.6
Hirsch, D.7
Watson, N.8
Gimeno, R.E.9
Stahl, A.10
-
37
-
-
0023499720
-
Immunohistochemical studies on the distribution and frequency of fatty-acid-binding protein positive cells in human fetal, newborn and adult liver tissues
-
T. Suzuki, and T. Ono Immunohistochemical studies on the distribution and frequency of fatty-acid-binding protein positive cells in human fetal, newborn and adult liver tissues J. Pathol. 153 1987 385 394
-
(1987)
J. Pathol.
, vol.153
, pp. 385-394
-
-
Suzuki, T.1
Ono, T.2
-
38
-
-
0024586979
-
Acinar heterogeneity of fatty acid binding protein expression in the livers of male, female and clofibrate-treated rats
-
N.M. Bass, M.E. Barker, J.A. Manning, A.L. Jones, and R.K. Ockner Acinar heterogeneity of fatty acid binding protein expression in the livers of male, female and clofibrate-treated rats Hepatology 9 1989 12 21
-
(1989)
Hepatology
, vol.9
, pp. 12-21
-
-
Bass, N.M.1
Barker, M.E.2
Manning, J.A.3
Jones, A.L.4
Ockner, R.K.5
-
39
-
-
0018776250
-
Sex differences in long chain fatty acid utilization and fatty acid binding protein concentration in rat liver
-
R.K. Ockner, D.A. Burnett, N. Lysenko, and J.A. Manning Sex differences in long chain fatty acid utilization and fatty acid binding protein concentration in rat liver J. Clin. Invest. 64 1979 172 181
-
(1979)
J. Clin. Invest.
, vol.64
, pp. 172-181
-
-
Ockner, R.K.1
Burnett, D.A.2
Lysenko, N.3
Manning, J.A.4
-
42
-
-
0018182489
-
The role of malonyl-CoA in the coordination of fatty acid synthesis and oxidation in isolated rat hepatocytes
-
J.D. McGarry, Y. Takabayashi, and D.W. Foster The role of malonyl-CoA in the coordination of fatty acid synthesis and oxidation in isolated rat hepatocytes J. Biol. Chem. 253 1978 8294 8300
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 8294-8300
-
-
McGarry, J.D.1
Takabayashi, Y.2
Foster, D.W.3
-
43
-
-
53349153430
-
Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease
-
N. Higuchi, M. Kato, Y. Shundo, H. Tajiri, M. Tanaka, N. Yamashita, M. Kohjima, K. Kotoh, M. Nakamuta, R. Takayanagi, and M. Enjoji Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease Hepatol. Res. 38 2008 1122 1129
-
(2008)
Hepatol. Res.
, vol.38
, pp. 1122-1129
-
-
Higuchi, N.1
Kato, M.2
Shundo, Y.3
Tajiri, H.4
Tanaka, M.5
Yamashita, N.6
Kohjima, M.7
Kotoh, K.8
Nakamuta, M.9
Takayanagi, R.10
Enjoji, M.11
-
44
-
-
0020682170
-
Heterogeneous distribution of ATP citrate lyase in rat-liver parenchyma. Microradiochemical determination in microdissected periportal and perivenous liver tissue
-
N.R. Katz, W. Fischer, and M. Ick Heterogeneous distribution of ATP citrate lyase in rat-liver parenchyma. Microradiochemical determination in microdissected periportal and perivenous liver tissue Eur. J. Biochem. 130 1983 297 301
-
(1983)
Eur. J. Biochem.
, vol.130
, pp. 297-301
-
-
Katz, N.R.1
Fischer, W.2
Ick, M.3
-
45
-
-
0024506258
-
Zonal distribution of fatty acid synthase in liver parenchyma of male and female rats
-
N. Katz, J. Thiele, and S. Giffhorn-Katz Zonal distribution of fatty acid synthase in liver parenchyma of male and female rats Eur. J. Biochem. 180 1989 185 189
-
(1989)
Eur. J. Biochem.
, vol.180
, pp. 185-189
-
-
Katz, N.1
Thiele, J.2
Giffhorn-Katz, S.3
-
46
-
-
0025242763
-
Zonal heterogeneity of the effects of chronic ethanol feeding on hepatic fatty acid metabolism
-
M. Guzmán, and J. Castro Zonal heterogeneity of the effects of chronic ethanol feeding on hepatic fatty acid metabolism Hepatology 12 1990 1098 1105
-
(1990)
Hepatology
, vol.12
, pp. 1098-1105
-
-
Guzmán, M.1
Castro, J.2
-
47
-
-
0028818499
-
Flexibility of zonation of fatty acid oxidation in rat liver
-
M. Guzmán, C. Bijleveld, and M.J. Geelen Flexibility of zonation of fatty acid oxidation in rat liver Biochem. J. 311 Pt 3 1995 853 860
-
(1995)
Biochem. J.
, vol.311
, Issue.PART 3
, pp. 853-860
-
-
Guzmán, M.1
Bijleveld, C.2
Geelen, M.J.3
-
49
-
-
0018801787
-
NADP-dependent dehydrogenases in rat liver parenchyma. II. Comparison of qualitative and quantitative G6PDH distribution patterns with particular reference to sex differences
-
H.F. Teutsch, and H. Rieder NADP-dependent dehydrogenases in rat liver parenchyma. II. Comparison of qualitative and quantitative G6PDH distribution patterns with particular reference to sex differences Histochemistry 60 1979 43 52
-
(1979)
Histochemistry
, vol.60
, pp. 43-52
-
-
Teutsch, H.F.1
Rieder, H.2
-
50
-
-
0027977909
-
Adaptive sex-dependent changes in the zonation of carbohydrate and lipid metabolism in rat liver lobules after partial hepatectomy
-
C.J. van Noorden, I.M. Vogels, and J. James Adaptive sex-dependent changes in the zonation of carbohydrate and lipid metabolism in rat liver lobules after partial hepatectomy Hepatology 20 1994 714 724
-
(1994)
Hepatology
, vol.20
, pp. 714-724
-
-
Van Noorden, C.J.1
Vogels, I.M.2
James, J.3
-
51
-
-
0026544694
-
Nutritional and hormonal regulation of lipogenic-enzyme gene expression in rat liver
-
N. Iritani Nutritional and hormonal regulation of lipogenic-enzyme gene expression in rat liver Eur. J. Biochem. 205 1992 433 442
-
(1992)
Eur. J. Biochem.
, vol.205
, pp. 433-442
-
-
Iritani, N.1
-
52
-
-
0025994850
-
Triiodothyronine-induced accumulations of malic enzyme, fatty acid synthase, acetyl-coenzyme A carboxylase, and their mRNAs are blocked by protein kinase inhibitors. Transcription is the affected step
-
J. Swierczynski, D.A. Mitchell, D.S. Reinhold, L.M. Salati, S.R. Stapleton, S.A. Klautky, A.E. Struve, and A.G. Goodridge Triiodothyronine-induced accumulations of malic enzyme, fatty acid synthase, acetyl-coenzyme A carboxylase, and their mRNAs are blocked by protein kinase inhibitors. Transcription is the affected step J. Biol. Chem. 266 1991 17459 17466
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 17459-17466
-
-
Swierczynski, J.1
Mitchell, D.A.2
Reinhold, D.S.3
Salati, L.M.4
Stapleton, S.R.5
Klautky, S.A.6
Struve, A.E.7
Goodridge, A.G.8
-
53
-
-
0029044299
-
Direct evidence for a role of the "spot 14" protein in the regulation of lipid synthesis
-
W.B. Kinlaw, J.L. Church, J. Harmon, and C.N. Mariash Direct evidence for a role of the "spot 14" protein in the regulation of lipid synthesis J. Biol. Chem. 270 1995 16615 16618
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 16615-16618
-
-
Kinlaw, W.B.1
Church, J.L.2
Harmon, J.3
Mariash, C.N.4
-
54
-
-
0023039297
-
Periportal and perivenous hepatocytes retain their zonal characteristics in primary culture
-
B. Quistorff, J. Dich, and N. Grunnet Periportal and perivenous hepatocytes retain their zonal characteristics in primary culture Biochem. Biophys. Res. Commun. 139 1986 1055 1061
-
(1986)
Biochem. Biophys. Res. Commun.
, vol.139
, pp. 1055-1061
-
-
Quistorff, B.1
Dich, J.2
Grunnet, N.3
-
55
-
-
78649553230
-
Transcription factors ETF, E2F, and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes
-
S. Zellmer, W. Schmidt-Heck, P. Godoy, H. Weng, C. Meyer, T. Lehmann, T. Sparna, W. Schormann, S. Hammad, C. Kreutz, J. Timmer, F. von Weizsäcker, P.A. Thürmann, I. Merfort, R. Guthke, S. Dooley, J.G. Hengstler, and R. Gebhardt Transcription factors ETF, E2F, and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes Hepatology 52 2010 2127 2136
-
(2010)
Hepatology
, vol.52
, pp. 2127-2136
-
-
Zellmer, S.1
Schmidt-Heck, W.2
Godoy, P.3
Weng, H.4
Meyer, C.5
Lehmann, T.6
Sparna, T.7
Schormann, W.8
Hammad, S.9
Kreutz, C.10
Timmer, J.11
Von Weizsäcker, F.12
Thürmann, P.A.13
Merfort, I.14
Guthke, R.15
Dooley, S.16
Hengstler, J.G.17
Gebhardt, R.18
-
56
-
-
0037031840
-
Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise
-
H. Park, V. Kaushik, S. Constant, M. Prentki, E. Przybytkowski, N.B. Ruderman, and A.K. Saha Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise J. Biol. Chem. 277 2002 32571 32577
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 32571-32577
-
-
Park, H.1
Kaushik, V.2
Constant, S.3
Prentki, M.4
Przybytkowski, E.5
Ruderman, N.B.6
Saha, A.K.7
-
57
-
-
3242656203
-
Triacylglycerol hydrolase: Role in intracellular lipid metabolism
-
V.W. Dolinsky, D. Gilham, M. Alam, D.E. Vance, and R. Lehner Triacylglycerol hydrolase: role in intracellular lipid metabolism Cell. Mol. Life Sci. 61 2004 1633 1651
-
(2004)
Cell. Mol. Life Sci.
, vol.61
, pp. 1633-1651
-
-
Dolinsky, V.W.1
Gilham, D.2
Alam, M.3
Vance, D.E.4
Lehner, R.5
-
58
-
-
0033559817
-
Subcellullar localization, developmental expression and characterization of a liver triacylglycerol hydrolase
-
R. Lehner, Z. Cui, and D.E. Vance Subcellullar localization, developmental expression and characterization of a liver triacylglycerol hydrolase Biochem. J. 338 Pt 3 1999 761 768
-
(1999)
Biochem. J.
, vol.338
, Issue.PART 3
, pp. 761-768
-
-
Lehner, R.1
Cui, Z.2
Vance, D.E.3
-
59
-
-
0028607505
-
Zonal differences in lipoprotein formation in the thioacetamide-induced micronodular-cirrhotic rat liver
-
H. Franke, I. Potratz, and R. Dargel Zonal differences in lipoprotein formation in the thioacetamide-induced micronodular-cirrhotic rat liver Exp. Toxicol. Pathol. 46 1994 503 511
-
(1994)
Exp. Toxicol. Pathol.
, vol.46
, pp. 503-511
-
-
Franke, H.1
Potratz, I.2
Dargel, R.3
-
60
-
-
27244449894
-
Endotoxin promotes preferential periportal upregulation of VLDL secretion in the rat liver
-
P. Aspichueta, S. Pérez, B. Ochoa, and O. Fresnedo Endotoxin promotes preferential periportal upregulation of VLDL secretion in the rat liver J. Lipid Res. 46 2005 1017 1026
-
(2005)
J. Lipid Res.
, vol.46
, pp. 1017-1026
-
-
Aspichueta, P.1
Pérez, S.2
Ochoa, B.3
Fresnedo, O.4
-
61
-
-
0037406445
-
Hepatic VLDL production in ob/ob mice is not stimulated by massive de novo lipogenesis but is less sensitive to the suppressive effects of insulin
-
C.H. Wiegman, R.H. Bandsma, M. Ouwens, F.H. van der Sluijs, R. Havinga, T. Boer, D.-J. Reijngoud, J.A. Romijn, and F. Kuipers Hepatic VLDL production in ob/ob mice is not stimulated by massive de novo lipogenesis but is less sensitive to the suppressive effects of insulin Diabetes 52 2003 1081 1089
-
(2003)
Diabetes
, vol.52
, pp. 1081-1089
-
-
Wiegman, C.H.1
Bandsma, R.H.2
Ouwens, M.3
Van Der Sluijs, F.H.4
Havinga, R.5
Boer, T.6
Reijngoud, D.-J.7
Romijn, J.A.8
Kuipers, F.9
-
62
-
-
34248359868
-
Pathology of fatty liver disease
-
E.M. Brunt Pathology of fatty liver disease Mod. Pathol. 20 Suppl. 1 2007 S40 S48
-
(2007)
Mod. Pathol.
, vol.20
, pp. S40-S48
-
-
Brunt, E.M.1
-
63
-
-
40949141827
-
Relationship of steatosis grade and zonal location to histological features of steatohepatitis in adult patients with non-alcoholic fatty liver disease
-
N. Chalasani, L. Wilson, D.E. Kleiner, O.W. Cummings, E.M. Brunt, and A. Unalp Relationship of steatosis grade and zonal location to histological features of steatohepatitis in adult patients with non-alcoholic fatty liver disease J. Hepatol. 48 2008 829 834
-
(2008)
J. Hepatol.
, vol.48
, pp. 829-834
-
-
Chalasani, N.1
Wilson, L.2
Kleiner, D.E.3
Cummings, O.W.4
Brunt, E.M.5
Unalp, A.6
-
64
-
-
0035960557
-
Effect of ischemia-reperfusion injury on the microcirculation of the steatotic liver of the Zucker rat
-
C.K. Sun, X.Y. Zhang, A. Zimmermann, G. Davis, and A.M. Wheatley Effect of ischemia-reperfusion injury on the microcirculation of the steatotic liver of the Zucker rat Transplantation 72 2001 1625 1631
-
(2001)
Transplantation
, vol.72
, pp. 1625-1631
-
-
Sun, C.K.1
Zhang, X.Y.2
Zimmermann, A.3
Davis, G.4
Wheatley, A.M.5
-
65
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
-
K.L. Donnelly, C.I. Smith, S.J. Schwarzenberg, J. Jessurun, M.D. Boldt, and E.J. Parks Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease J. Clin. Invest. 115 2005 1343 1351
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1343-1351
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
Jessurun, J.4
Boldt, M.D.5
Parks, E.J.6
-
66
-
-
35148881190
-
Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease
-
M. Kohjima, M. Enjoji, N. Higuchi, M. Kato, K. Kotoh, T. Yoshimoto, T. Fujino, M. Yada, R. Yada, N. Harada, R. Takayanagi, and M. Nakamuta Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease Int. J. Mol. Med. 20 2007 351 358
-
(2007)
Int. J. Mol. Med.
, vol.20
, pp. 351-358
-
-
Kohjima, M.1
Enjoji, M.2
Higuchi, N.3
Kato, M.4
Kotoh, K.5
Yoshimoto, T.6
Fujino, T.7
Yada, M.8
Yada, R.9
Harada, N.10
Takayanagi, R.11
Nakamuta, M.12
-
67
-
-
0032921269
-
Differential expression of apolipoprotein e messenger RNA within the rat liver lobule determined by in situ hybridization
-
M. Massimi, S.R. Lear, D.L. Williams, A.L. Jones, and S.K. Erickson Differential expression of apolipoprotein E messenger RNA within the rat liver lobule determined by in situ hybridization Hepatology 29 1999 1549 1555
-
(1999)
Hepatology
, vol.29
, pp. 1549-1555
-
-
Massimi, M.1
Lear, S.R.2
Williams, D.L.3
Jones, A.L.4
Erickson, S.K.5
-
68
-
-
0028900372
-
Tissue-specific, developmental and nutritional regulation of the gene encoding the catalytic subunit of the rat apolipoprotein B mRNA editing enzyme: Functional role in the modulation of apoB mRNA editing
-
T. Funahashi, F. Giannoni, A.M. DePaoli, S.F. Skarosi, and N.O. Davidson Tissue-specific, developmental and nutritional regulation of the gene encoding the catalytic subunit of the rat apolipoprotein B mRNA editing enzyme: functional role in the modulation of apoB mRNA editing J. Lipid Res. 36 1995 414 428
-
(1995)
J. Lipid Res.
, vol.36
, pp. 414-428
-
-
Funahashi, T.1
Giannoni, F.2
Depaoli, A.M.3
Skarosi, S.F.4
Davidson, N.O.5
-
69
-
-
84881317164
-
Cell-to-cell heterogeneity in lipid droplets suggests a mechanism to reduce lipotoxicity
-
A. Herms, M. Bosch, N. Ariotti, B.J.N. Reddy, A. Fajardo, A. Fernández-Vidal, A. Alvarez-Guaita, M.A. Fernández-Rojo, C. Rentero, F. Tebar, C. Enrich, M.-I. Geli, R.G. Parton, S.P. Gross, and A. Pol Cell-to-cell heterogeneity in lipid droplets suggests a mechanism to reduce lipotoxicity Curr. Biol. 23 2013 1489 1496
-
(2013)
Curr. Biol.
, vol.23
, pp. 1489-1496
-
-
Herms, A.1
Bosch, M.2
Ariotti, N.3
Reddy, B.J.N.4
Fajardo, A.5
Fernández-Vidal, A.6
Alvarez-Guaita, A.7
Fernández-Rojo, M.A.8
Rentero, C.9
Tebar, F.10
Enrich, C.11
Geli, M.-I.12
Parton, R.G.13
Gross, S.P.14
Pol, A.15
-
70
-
-
84887005701
-
Intracellular lipid content is a key intrinsic determinant for hepatocyte viability and metabolic and inflammatory states in mice
-
L. Sheng, B. Jiang, and L. Rui Intracellular lipid content is a key intrinsic determinant for hepatocyte viability and metabolic and inflammatory states in mice Am. J. Physiol. Endocrinol. Metab. 305 2013 E1115 E1123
-
(2013)
Am. J. Physiol. Endocrinol. Metab.
, vol.305
, pp. E1115-E1123
-
-
Sheng, L.1
Jiang, B.2
Rui, L.3
-
71
-
-
0027160660
-
Regulation of the long-chain carnitine acyltransferases
-
P.S. Brady, R.R. Ramsay, and L.J. Brady Regulation of the long-chain carnitine acyltransferases FASEB J. 7 1993 1039 1044
-
(1993)
FASEB J.
, vol.7
, pp. 1039-1044
-
-
Brady, P.S.1
Ramsay, R.R.2
Brady, L.J.3
-
72
-
-
0032745356
-
What factors are responsible for the greater yield of ATP per carbon atom when fatty acids are completely oxidised to CO2 and water compared with glucose?
-
I.G. Darvey What factors are responsible for the greater yield of ATP per carbon atom when fatty acids are completely oxidised to CO2 and water compared with glucose? Biochem. Educ. 27 1999 209 210
-
(1999)
Biochem. Educ.
, vol.27
, pp. 209-210
-
-
Darvey, I.G.1
-
73
-
-
0025032691
-
Fatty acid-binding protein expression in the liver: Its regulation and relationship to the zonation of fatty acid metabolism
-
N.M. Bass Fatty acid-binding protein expression in the liver: its regulation and relationship to the zonation of fatty acid metabolism Mol. Cell. Biochem. 98 1990 167 176
-
(1990)
Mol. Cell. Biochem.
, vol.98
, pp. 167-176
-
-
Bass, N.M.1
-
74
-
-
0023164955
-
Quantitation of ketogenesis in periportal and pericentral regions of the liver lobule
-
M.J. Olson, and R.G. Thurman Quantitation of ketogenesis in periportal and pericentral regions of the liver lobule Arch. Biochem. Biophys. 253 1987 26 37
-
(1987)
Arch. Biochem. Biophys.
, vol.253
, pp. 26-37
-
-
Olson, M.J.1
Thurman, R.G.2
-
75
-
-
0019975590
-
Lipogenesis from ketone bodies in the isolated perfused rat liver. Evidence for the cytosolic activation of acetoacetate
-
G. Endemann, P.G. Goetz, J. Edmond, and H. Brunengraber Lipogenesis from ketone bodies in the isolated perfused rat liver. Evidence for the cytosolic activation of acetoacetate J. Biol. Chem. 257 1982 3434 3440
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 3434-3440
-
-
Endemann, G.1
Goetz, P.G.2
Edmond, J.3
Brunengraber, H.4
-
76
-
-
0025202673
-
Ketone body utilization for lipogenesis in the perfused liver of the obese Zucker rat
-
M.J. Azain, and J.A. Ontko Ketone body utilization for lipogenesis in the perfused liver of the obese Zucker rat Horm. Metab. Res. 22 1990 561 565
-
(1990)
Horm. Metab. Res.
, vol.22
, pp. 561-565
-
-
Azain, M.J.1
Ontko, J.A.2
-
77
-
-
0028908866
-
Immunolocalization of mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase in rat liver
-
T. Royo, M.J. Pedragosa, J. Ayté, G. Gil-Gómez, S. Vilaró, and F.G. Hegardt Immunolocalization of mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase in rat liver J. Cell. Physiol. 162 1995 103 109
-
(1995)
J. Cell. Physiol.
, vol.162
, pp. 103-109
-
-
Royo, T.1
Pedragosa, M.J.2
Ayté, J.3
Gil-Gómez, G.4
Vilaró, S.5
Hegardt, F.G.6
-
79
-
-
77952561299
-
Bile acids as regulators of hepatic lipid and glucose metabolism
-
M. Trauner, T. Claudel, P. Fickert, T. Moustafa, and M. Wagner Bile acids as regulators of hepatic lipid and glucose metabolism Dig. Dis. 28 2010 220 224
-
(2010)
Dig. Dis.
, vol.28
, pp. 220-224
-
-
Trauner, M.1
Claudel, T.2
Fickert, P.3
Moustafa, T.4
Wagner, M.5
-
80
-
-
84887599824
-
Bile acid-mediated control of liver triglycerides
-
C. Fuchs, T. Claudel, and M. Trauner Bile acid-mediated control of liver triglycerides Semin. Liver Dis. 33 2013 330 342
-
(2013)
Semin. Liver Dis.
, vol.33
, pp. 330-342
-
-
Fuchs, C.1
Claudel, T.2
Trauner, M.3
-
81
-
-
0027528564
-
Zonation of cholesterol and glycerolipid synthesis in regenerating rat livers
-
H.C. Cheng, C.M. Yang, and M.S. Shiao Zonation of cholesterol and glycerolipid synthesis in regenerating rat livers Hepatology 17 1993 280 286
-
(1993)
Hepatology
, vol.17
, pp. 280-286
-
-
Cheng, H.C.1
Yang, C.M.2
Shiao, M.S.3
-
82
-
-
0342912311
-
Hydroxymethylglutaryl-coenzyme A reductase-containing hepatocytes are distributed periportally in normal and mevinolin-treated rat livers
-
I.I. Singer, D.W. Kawka, D.M. Kazazis, A.W. Alberts, J.S. Chen, J.W. Huff, and G.C. Ness Hydroxymethylglutaryl-coenzyme A reductase-containing hepatocytes are distributed periportally in normal and mevinolin-treated rat livers Proc. Natl. Acad. Sci. U. S. A. 81 1984 5556 5560
-
(1984)
Proc. Natl. Acad. Sci. U. S. A.
, vol.81
, pp. 5556-5560
-
-
Singer, I.I.1
Kawka, D.W.2
Kazazis, D.M.3
Alberts, A.W.4
Chen, J.S.5
Huff, J.W.6
Ness, G.C.7
-
83
-
-
0023918754
-
Localization of 3-hydroxy-3-methylglutaryl CoA reductase and 3-hydroxy-3-methylglutaryl CoA synthase in the rat liver and intestine is affected by cholestyramine and mevinolin
-
A.C. Li, R.D. Tanaka, K. Callaway, A.M. Fogelman, and P.A. Edwards Localization of 3-hydroxy-3-methylglutaryl CoA reductase and 3-hydroxy-3-methylglutaryl CoA synthase in the rat liver and intestine is affected by cholestyramine and mevinolin J. Lipid Res. 29 1988 781 796
-
(1988)
J. Lipid Res.
, vol.29
, pp. 781-796
-
-
Li, A.C.1
Tanaka, R.D.2
Callaway, K.3
Fogelman, A.M.4
Edwards, P.A.5
-
84
-
-
33750536032
-
Differential gene expression in periportal and perivenous mouse hepatocytes
-
A. Braeuning, C. Ittrich, C. Köhle, S. Hailfinger, M. Bonin, A. Buchmann, and M. Schwarz Differential gene expression in periportal and perivenous mouse hepatocytes FEBS J. 273 2006 5051 5061
-
(2006)
FEBS J.
, vol.273
, pp. 5051-5061
-
-
Braeuning, A.1
Ittrich, C.2
Köhle, C.3
Hailfinger, S.4
Bonin, M.5
Buchmann, A.6
Schwarz, M.7
-
85
-
-
33846991643
-
Localization of the pre-squalene segment of the isoprenoid biosynthetic pathway in mammalian peroxisomes
-
W.J. Kovacs, K.N. Tape, J.E. Shackelford, X. Duan, T. Kasumov, J.K. Kelleher, H. Brunengraber, and S.K. Krisans Localization of the pre-squalene segment of the isoprenoid biosynthetic pathway in mammalian peroxisomes Histochem. Cell Biol. 127 2007 273 290
-
(2007)
Histochem. Cell Biol.
, vol.127
, pp. 273-290
-
-
Kovacs, W.J.1
Tape, K.N.2
Shackelford, J.E.3
Duan, X.4
Kasumov, T.5
Kelleher, J.K.6
Brunengraber, H.7
Krisans, S.K.8
-
86
-
-
0025847766
-
Heterogeneity of rat liver parenchyma in cholesterol 7 alpha-hydroxylase and bile acid synthesis
-
B. Ugele, H.J. Kempen, J.M. Kempen, R. Gebhardt, P. Meijer, H.J. Burger, and H.M. Princen Heterogeneity of rat liver parenchyma in cholesterol 7 alpha-hydroxylase and bile acid synthesis Biochem. J. 276 Pt 1 1991 73 77
-
(1991)
Biochem. J.
, vol.276
, Issue.PART 1
, pp. 73-77
-
-
Ugele, B.1
Kempen, H.J.2
Kempen, J.M.3
Gebhardt, R.4
Meijer, P.5
Burger, H.J.6
Princen, H.M.7
-
87
-
-
33846970566
-
Differential hepatocellular zonation pattern of cholesterol 7alpha-hydroxylase (Cyp7a1) and sterol 12alpha-hydroxylase (Cyp8b1) in the mouse
-
J. Wang, M. Olin, B. Rozell, I. Björkhem, C. Einarsson, G. Eggertsen, and M. Gåfvels Differential hepatocellular zonation pattern of cholesterol 7alpha-hydroxylase (Cyp7a1) and sterol 12alpha-hydroxylase (Cyp8b1) in the mouse Histochem. Cell Biol. 127 2007 253 261
-
(2007)
Histochem. Cell Biol.
, vol.127
, pp. 253-261
-
-
Wang, J.1
Olin, M.2
Rozell, B.3
Björkhem, I.4
Einarsson, C.5
Eggertsen, G.6
Gåfvels, M.7
-
88
-
-
0038064375
-
The 3alpha-hydroxy-steroid-dehydrogenase-mRNA and -protein are more prevalent in pericentral than in periportal hepatocytes
-
U. Baumgartner, P. Baier, O. Birke, and E.H. Farthmann The 3alpha-hydroxy-steroid-dehydrogenase-mRNA and -protein are more prevalent in pericentral than in periportal hepatocytes Eur. J. Gastroenterol. Hepatol. 15 2003 509 513
-
(2003)
Eur. J. Gastroenterol. Hepatol.
, vol.15
, pp. 509-513
-
-
Baumgartner, U.1
Baier, P.2
Birke, O.3
Farthmann, E.H.4
-
89
-
-
0028933724
-
Change of zonal bile acid processing after partial hepatectomy in the rat
-
U. Baumgartner, M. Sellinger, G. Ruf, L. Jehle, C. Ihling, and E.H. Farthmann Change of zonal bile acid processing after partial hepatectomy in the rat J. Hepatol. 22 1995 474 480
-
(1995)
J. Hepatol.
, vol.22
, pp. 474-480
-
-
Baumgartner, U.1
Sellinger, M.2
Ruf, G.3
Jehle, L.4
Ihling, C.5
Farthmann, E.H.6
-
90
-
-
75549086552
-
Bile acids and metabolic regulation: Mechanisms and clinical responses to bile acid sequestration
-
B. Staels, and V.A. Fonseca Bile acids and metabolic regulation: mechanisms and clinical responses to bile acid sequestration Diabetes Care 32 Suppl. 2 2009 S237 S245
-
(2009)
Diabetes Care
, vol.32
, pp. S237-S245
-
-
Staels, B.1
Fonseca, V.A.2
-
91
-
-
0025205111
-
Bile acids exert negative feedback control on bile acid synthesis in cultured pig hepatocytes by suppression of cholesterol 7 alpha-hydroxylase activity
-
J. Kwekkeboom, H.M. Princen, E.M. van Voorthuizen, and H.J. Kempen Bile acids exert negative feedback control on bile acid synthesis in cultured pig hepatocytes by suppression of cholesterol 7 alpha-hydroxylase activity Hepatology 12 1990 1209 1215
-
(1990)
Hepatology
, vol.12
, pp. 1209-1215
-
-
Kwekkeboom, J.1
Princen, H.M.2
Van Voorthuizen, E.M.3
Kempen, H.J.4
-
92
-
-
0033977092
-
Biliary excretion of bile acids and organic anions in zone 1- and zone 3-injured rats
-
M. Aiso, H. Takikawa, and M. Yamanaka Biliary excretion of bile acids and organic anions in zone 1- and zone 3-injured rats Liver 20 2000 38 44
-
(2000)
Liver
, vol.20
, pp. 38-44
-
-
Aiso, M.1
Takikawa, H.2
Yamanaka, M.3
-
94
-
-
0030032280
-
The establishment of the hepatic architecture is a prerequisite for the development of a lobular pattern of gene expression
-
R.G. Notenboom, P.A. de Boer, A.F. Moorman, and W.H. Lamers The establishment of the hepatic architecture is a prerequisite for the development of a lobular pattern of gene expression Development 122 1996 321 332
-
(1996)
Development
, vol.122
, pp. 321-332
-
-
Notenboom, R.G.1
De Boer, P.A.2
Moorman, A.F.3
Lamers, W.H.4
-
95
-
-
0026688647
-
Cell-cell interactions: Clues to hepatocyte heterogeneity and beyond?
-
R. Gebhardt Cell-cell interactions: clues to hepatocyte heterogeneity and beyond? Hepatology 16 1992 843 845
-
(1992)
Hepatology
, vol.16
, pp. 843-845
-
-
Gebhardt, R.1
-
96
-
-
0025131373
-
Induction of glutamine synthetase in periportal hepatocytes by cocultivation with a liver epithelial cell line
-
W. Schrode, D. Mecke, and R. Gebhardt Induction of glutamine synthetase in periportal hepatocytes by cocultivation with a liver epithelial cell line Eur. J. Cell Biol. 53 1990 35 41
-
(1990)
Eur. J. Cell Biol.
, vol.53
, pp. 35-41
-
-
Schrode, W.1
Mecke, D.2
Gebhardt, R.3
-
97
-
-
33947139689
-
Hepatocellular expression of glutamine synthetase: An indicator of morphogen actions as master regulators of zonation in adult liver
-
R. Gebhardt, A. Baldysiak-Figiel, V. Krügel, E. Ueberham, and F. Gaunitz Hepatocellular expression of glutamine synthetase: an indicator of morphogen actions as master regulators of zonation in adult liver Prog. Histochem. Cytochem. 41 2007 201 266
-
(2007)
Prog. Histochem. Cytochem.
, vol.41
, pp. 201-266
-
-
Gebhardt, R.1
Baldysiak-Figiel, A.2
Krügel, V.3
Ueberham, E.4
Gaunitz, F.5
-
98
-
-
0030819160
-
Cell-cell interactions in the regulation of the expression of hepatic enzymes
-
R. Gebhardt, and F. Gaunitz Cell-cell interactions in the regulation of the expression of hepatic enzymes Cell Biol. Toxicol. 13 1997 263 273
-
(1997)
Cell Biol. Toxicol.
, vol.13
, pp. 263-273
-
-
Gebhardt, R.1
Gaunitz, F.2
-
99
-
-
0025933048
-
Evidence that interaction of hepatocytes with the collecting (hepatic) veins triggers position-specific transcription of the glutamine synthetase and ornithine aminotransferase genes in the mouse liver
-
F.C. Kuo, and J.E. Darnell Evidence that interaction of hepatocytes with the collecting (hepatic) veins triggers position-specific transcription of the glutamine synthetase and ornithine aminotransferase genes in the mouse liver Mol. Cell. Biol. 11 1991 6050 6058
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 6050-6058
-
-
Kuo, F.C.1
Darnell, J.E.2
-
100
-
-
0026697211
-
Extracellular matrix gradients in the space of Disse: Relevance to liver biology
-
L.M. Reid, A.S. Fiorino, S.H. Sigal, S. Brill, and P.A. Holst Extracellular matrix gradients in the space of Disse: relevance to liver biology Hepatology 15 1992 1198 1203
-
(1992)
Hepatology
, vol.15
, pp. 1198-1203
-
-
Reid, L.M.1
Fiorino, A.S.2
Sigal, S.H.3
Brill, S.4
Holst, P.A.5
-
101
-
-
0027442441
-
Experimental evidence that the physiological position of the liver within the circulation is not a major determinant of zonation of gene expression
-
G.T. Wagenaar, R.A. Chamuleau, J.G. de Haan, M.A. Maas, P.A.J. de Boer, F. Marx, A.F. Moorman, W.M. Frederiks, and W.H. Lamers Experimental evidence that the physiological position of the liver within the circulation is not a major determinant of zonation of gene expression Hepatology 18 1993 1144 1153
-
(1993)
Hepatology
, vol.18
, pp. 1144-1153
-
-
Wagenaar, G.T.1
Chamuleau, R.A.2
De Haan, J.G.3
Maas, M.A.4
De Boer, P.A.J.5
Marx, F.6
Moorman, A.F.7
Frederiks, W.M.8
Lamers, W.H.9
-
102
-
-
0032898916
-
A mechanistic model for the development and maintenance of portocentral gradients in gene expression in the liver
-
V.M. Christoffels, H. Sassi, J.M. Ruijter, A.F. Moorman, T. Grange, and W.H. Lamers A mechanistic model for the development and maintenance of portocentral gradients in gene expression in the liver Hepatology 29 1999 1180 1192
-
(1999)
Hepatology
, vol.29
, pp. 1180-1192
-
-
Christoffels, V.M.1
Sassi, H.2
Ruijter, J.M.3
Moorman, A.F.4
Grange, T.5
Lamers, W.H.6
-
103
-
-
0020682142
-
Changes in availability of glucogenic and ketogenic substrates and liver metabolism in fed or starved rats
-
C. Rémésy, and C. Demigné Changes in availability of glucogenic and ketogenic substrates and liver metabolism in fed or starved rats Ann. Nutr. Metab. 27 1983 57 70
-
(1983)
Ann. Nutr. Metab.
, vol.27
, pp. 57-70
-
-
Rémésy, C.1
Demigné, C.2
-
104
-
-
0006132932
-
Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma
-
S.A. Kliewer, S.S. Sundseth, S.A. Jones, P.J. Brown, G.B. Wisely, C.S. Koble, P. Devchand, W. Wahli, T.M. Willson, J.M. Lenhard, and J.M. Lehmann Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma Proc. Natl. Acad. Sci. U. S. A. 94 1997 4318 4323
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 4318-4323
-
-
Kliewer, S.A.1
Sundseth, S.S.2
Jones, S.A.3
Brown, P.J.4
Wisely, G.B.5
Koble, C.S.6
Devchand, P.7
Wahli, W.8
Willson, T.M.9
Lenhard, J.M.10
Lehmann, J.M.11
-
105
-
-
4344701247
-
The multi-dimensional regulation of gene expression by fatty acids: Polyunsaturated fats as nutrient sensors
-
S.D. Clarke The multi-dimensional regulation of gene expression by fatty acids: polyunsaturated fats as nutrient sensors Curr. Opin. Lipidol. 15 2004 13 18
-
(2004)
Curr. Opin. Lipidol.
, vol.15
, pp. 13-18
-
-
Clarke, S.D.1
-
106
-
-
4444242510
-
Control of gene expression by fatty acids
-
J.-P. Pégorier, C. Le May, and J. Girard Control of gene expression by fatty acids J. Nutr. 134 2004 2444S 2449S
-
(2004)
J. Nutr.
, vol.134
, pp. 2444S-2449S
-
-
Pégorier, J.-P.1
Le May, C.2
Girard, J.3
-
107
-
-
0037371120
-
Hepatocyte nuclear factor 1 alpha: A key mediator of the effect of bile acids on gene expression
-
D. Jung, and G.A. Kullak-Ublick Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression Hepatology 37 2003 622 631
-
(2003)
Hepatology
, vol.37
, pp. 622-631
-
-
Jung, D.1
Kullak-Ublick, G.A.2
-
108
-
-
58249110568
-
Role of bile acids and bile acid receptors in metabolic regulation
-
P. Lefebvre, B. Cariou, F. Lien, F. Kuipers, and B. Staels Role of bile acids and bile acid receptors in metabolic regulation Physiol. Rev. 89 2009 147 191
-
(2009)
Physiol. Rev.
, vol.89
, pp. 147-191
-
-
Lefebvre, P.1
Cariou, B.2
Lien, F.3
Kuipers, F.4
Staels, B.5
-
109
-
-
77950602541
-
Bile salt sequestration induces hepatic de novo lipogenesis through farnesoid X receptor- and liver X receptorα-controlled metabolic pathways in mice
-
H. Herrema, M. Meissner, T.H. van Dijk, G. Brufau, R. Boverhof, M.H. Oosterveer, D.-J. Reijngoud, M. Müller, F. Stellaard, A.K. Groen, and F. Kuipers Bile salt sequestration induces hepatic de novo lipogenesis through farnesoid X receptor- and liver X receptorα-controlled metabolic pathways in mice Hepatology 51 2010 806 816
-
(2010)
Hepatology
, vol.51
, pp. 806-816
-
-
Herrema, H.1
Meissner, M.2
Van Dijk, T.H.3
Brufau, G.4
Boverhof, R.5
Oosterveer, M.H.6
Reijngoud, D.-J.7
Müller, M.8
Stellaard, F.9
Groen, A.K.10
Kuipers, F.11
-
110
-
-
0031020095
-
Role of oxygen in the zonation of carbohydrate metabolism and gene expression in liver
-
K. Jungermann, and T. Kietzmann Role of oxygen in the zonation of carbohydrate metabolism and gene expression in liver Kidney Int. 51 1997 402 412
-
(1997)
Kidney Int.
, vol.51
, pp. 402-412
-
-
Jungermann, K.1
Kietzmann, T.2
-
111
-
-
0033960898
-
Oxygen: Modulator of metabolic zonation and disease of the liver
-
K. Jungermann, and T. Kietzmann Oxygen: modulator of metabolic zonation and disease of the liver Hepatology 31 2000 255 260
-
(2000)
Hepatology
, vol.31
, pp. 255-260
-
-
Jungermann, K.1
Kietzmann, T.2
-
112
-
-
31944438744
-
Oxygen: Modulator of physiological and pathophysiological processes in the liver
-
T. Kietzmann, E.Y. Dimova, D. Flügel, and J.-G. Scharf Oxygen: modulator of physiological and pathophysiological processes in the liver Z. Gastroenterol. 44 2006 67 76
-
(2006)
Z. Gastroenterol.
, vol.44
, pp. 67-76
-
-
Kietzmann, T.1
Dimova, E.Y.2
Flügel, D.3
Scharf, J.-G.4
-
113
-
-
33645635004
-
Modulation of liver functions expressed by Hepg2 cells by limiting oxygen diffusion
-
J.C.A. Camp Modulation of liver functions expressed by Hepg2 cells by limiting oxygen diffusion AIChE Conf. Proc 2005
-
(2005)
AIChE Conf. Proc
-
-
Camp, J.C.A.1
-
114
-
-
0019809984
-
Modulation of the glucagon-dependent induction of phosphoenolpyruvate carboxykinase and tyrosine aminotransferase by arterial and venous oxygen concentrations in hepatocyte cultures
-
M. Nauck, D. Wölfle, N. Katz, and K. Jungermann Modulation of the glucagon-dependent induction of phosphoenolpyruvate carboxykinase and tyrosine aminotransferase by arterial and venous oxygen concentrations in hepatocyte cultures Eur. J. Biochem. 119 1981 657 661
-
(1981)
Eur. J. Biochem.
, vol.119
, pp. 657-661
-
-
Nauck, M.1
Wölfle, D.2
Katz, N.3
Jungermann, K.4
-
115
-
-
0022410591
-
Long-term effects of physiological oxygen concentrations on glycolysis and gluconeogenesis in hepatocyte cultures
-
D. Wölfle, and K. Jungermann Long-term effects of physiological oxygen concentrations on glycolysis and gluconeogenesis in hepatocyte cultures Eur. J. Biochem. 151 1985 299 303
-
(1985)
Eur. J. Biochem.
, vol.151
, pp. 299-303
-
-
Wölfle, D.1
Jungermann, K.2
-
116
-
-
84885466792
-
A theoretical study of lipid accumulation in the liver - Implications for nonalcoholic fatty liver disease
-
J. Schleicher, R. Guthke, U. Dahmen, O. Dirsch, H.G. Holzhütter, and S. Schuster A theoretical study of lipid accumulation in the liver - implications for nonalcoholic fatty liver disease Biochim. Biophys. Acta 1841 2014 62 69
-
(2014)
Biochim. Biophys. Acta
, vol.1841
, pp. 62-69
-
-
Schleicher, J.1
Guthke, R.2
Dahmen, U.3
Dirsch, O.4
Holzhütter, H.G.5
Schuster, S.6
-
117
-
-
68949098346
-
Hypoxia-inducible factor 2 regulates hepatic lipid metabolism
-
E.B. Rankin, J. Rha, M.A. Selak, T.L. Unger, B. Keith, Q. Liu, and V.H. Haase Hypoxia-inducible factor 2 regulates hepatic lipid metabolism Mol. Cell. Biol. 29 2009 4527 4538
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 4527-4538
-
-
Rankin, E.B.1
Rha, J.2
Selak, M.A.3
Unger, T.L.4
Keith, B.5
Liu, Q.6
Haase, V.H.7
-
118
-
-
79960745146
-
Hypoxia-inducible transcription factor 2α promotes steatohepatitis through augmenting lipid accumulation, inflammation, and fibrosis
-
A. Qu, M. Taylor, X. Xue, T. Matsubara, D. Metzger, P. Chambon, F.J. Gonzalez, and Y.M. Shah Hypoxia-inducible transcription factor 2α promotes steatohepatitis through augmenting lipid accumulation, inflammation, and fibrosis Hepatology 54 2011 472 483
-
(2011)
Hepatology
, vol.54
, pp. 472-483
-
-
Qu, A.1
Taylor, M.2
Xue, X.3
Matsubara, T.4
Metzger, D.5
Chambon, P.6
Gonzalez, F.J.7
Shah, Y.M.8
-
119
-
-
84862854714
-
Hypoxia-inducible factors and their roles in energy metabolism
-
N. Goda, and M. Kanai Hypoxia-inducible factors and their roles in energy metabolism Int. J. Hematol. 95 2012 457 463
-
(2012)
Int. J. Hematol.
, vol.95
, pp. 457-463
-
-
Goda, N.1
Kanai, M.2
-
120
-
-
0035868277
-
Perivenous expression of the mRNA of the three hypoxia-inducible factor alpha-subunits, HIF1alpha, HIF2alpha and HIF3alpha, in rat liver
-
T. Kietzmann, Y. Cornesse, K. Brechtel, S. Modaressi, and K. Jungermann Perivenous expression of the mRNA of the three hypoxia-inducible factor alpha-subunits, HIF1alpha, HIF2alpha and HIF3alpha, in rat liver Biochem. J. 354 2001 531 537
-
(2001)
Biochem. J.
, vol.354
, pp. 531-537
-
-
Kietzmann, T.1
Cornesse, Y.2
Brechtel, K.3
Modaressi, S.4
Jungermann, K.5
-
121
-
-
84887579055
-
The role of gastrointestinal hormones in hepatic lipid metabolism
-
J.E. Mells, and F.A. Anania The role of gastrointestinal hormones in hepatic lipid metabolism Semin. Liver Dis. 33 2013 343 357
-
(2013)
Semin. Liver Dis.
, vol.33
, pp. 343-357
-
-
Mells, J.E.1
Anania, F.A.2
-
122
-
-
80055082476
-
Insulin-dependent suppression of cholesterol 7alpha-hydroxlase is a possible link between glucose and cholesterol metabolisms
-
W.H. Park, and Y.K. Pak Insulin-dependent suppression of cholesterol 7alpha-hydroxlase is a possible link between glucose and cholesterol metabolisms Exp. Mol. Med. 43 2011 571 579
-
(2011)
Exp. Mol. Med.
, vol.43
, pp. 571-579
-
-
Park, W.H.1
Pak, Y.K.2
-
123
-
-
0018864840
-
Regulation of hepatic fatty acid oxidation and ketone body production
-
J.D. McGarry, and D.W. Foster Regulation of hepatic fatty acid oxidation and ketone body production Annu. Rev. Biochem. 49 1980 395 420
-
(1980)
Annu. Rev. Biochem.
, vol.49
, pp. 395-420
-
-
McGarry, J.D.1
Foster, D.W.2
-
124
-
-
77957843089
-
Insulin-induced gene: A new regulator in lipid metabolism
-
X.-Y. Dong, and S.-Q. Tang Insulin-induced gene: a new regulator in lipid metabolism Peptides 31 2010 2145 2150
-
(2010)
Peptides
, vol.31
, pp. 2145-2150
-
-
Dong, X.-Y.1
Tang, S.-Q.2
-
125
-
-
0015250464
-
The immediate effects of insulin and fructose on the metabolism of the perfused liver. Changes in lipoprotein secretion, fatty acid oxidation and esterification, lipogenesis and carbohydrate metabolism
-
D.L. Topping, and P.A. Mayes The immediate effects of insulin and fructose on the metabolism of the perfused liver. Changes in lipoprotein secretion, fatty acid oxidation and esterification, lipogenesis and carbohydrate metabolism Biochem. J. 126 1972 295 311
-
(1972)
Biochem. J.
, vol.126
, pp. 295-311
-
-
Topping, D.L.1
Mayes, P.A.2
-
126
-
-
0019887383
-
The effects of insulin and glucagon on the release of triacylglycerols by isolated rat hepatocytes are mere reflections of the hormonal effects on the rate of triacylglycerol synthesis
-
A.C. Beynen, H.P. Haagsman, L.M. van Golde, and M.J. Geelen The effects of insulin and glucagon on the release of triacylglycerols by isolated rat hepatocytes are mere reflections of the hormonal effects on the rate of triacylglycerol synthesis Biochim. Biophys. Acta 665 1981 1 7
-
(1981)
Biochim. Biophys. Acta
, vol.665
, pp. 1-7
-
-
Beynen, A.C.1
Haagsman, H.P.2
Van Golde, L.M.3
Geelen, M.J.4
-
127
-
-
0036348050
-
The roles of insulin and fatty acids in the regulation of hepatic very-low-density lipoprotein assembly
-
G.F. Gibbons, A.M. Brown, D. Wiggins, and R. Pease The roles of insulin and fatty acids in the regulation of hepatic very-low-density lipoprotein assembly J. R. Soc. Med. 95 Suppl. 42 2002 23 32
-
(2002)
J. R. Soc. Med.
, vol.95
, pp. 23-32
-
-
Gibbons, G.F.1
Brown, A.M.2
Wiggins, D.3
Pease, R.4
-
128
-
-
26444526245
-
Insulin, glucagon and fatty acid treatment of hepatocytes does not result in phosphorylation or changes in activity of triacylglycerol hydrolase
-
D. Gilham, K.R. Perreault, C.F.B. Holmes, D.N. Brindley, D.E. Vance, and R. Lehner Insulin, glucagon and fatty acid treatment of hepatocytes does not result in phosphorylation or changes in activity of triacylglycerol hydrolase Biochim. Biophys. Acta 1736 2005 189 199
-
(2005)
Biochim. Biophys. Acta
, vol.1736
, pp. 189-199
-
-
Gilham, D.1
Perreault, K.R.2
Holmes, C.F.B.3
Brindley, D.N.4
Vance, D.E.5
Lehner, R.6
-
129
-
-
34848891301
-
Acute suppression of VLDL1 secretion rate by insulin is associated with hepatic fat content and insulin resistance
-
M. Adiels, J. Westerbacka, A. Soro-Paavonen, A.M. Häkkinen, S. Vehkavaara, M.J. Caslake, C. Packard, S.O. Olofsson, H. Yki-Järvinen, M.R. Taskinen, and J. Borén Acute suppression of VLDL1 secretion rate by insulin is associated with hepatic fat content and insulin resistance Diabetologia 50 2007 2356 2365
-
(2007)
Diabetologia
, vol.50
, pp. 2356-2365
-
-
Adiels, M.1
Westerbacka, J.2
Soro-Paavonen, A.3
Häkkinen, A.M.4
Vehkavaara, S.5
Caslake, M.J.6
Packard, C.7
Olofsson, S.O.8
Yki-Järvinen, H.9
Taskinen, M.R.10
Borén, J.11
-
130
-
-
0021269073
-
Regulation of peripheral insulin/glucagon levels by rat liver
-
H.J. Balks, and K. Jungermann Regulation of peripheral insulin/glucagon levels by rat liver Eur. J. Biochem. 141 1984 645 650
-
(1984)
Eur. J. Biochem.
, vol.141
, pp. 645-650
-
-
Balks, H.J.1
Jungermann, K.2
-
131
-
-
43249095748
-
Mechanisms determining phenotypic heterogeneity of hepatocytes
-
I.F. Usynin, and L.E. Panin Mechanisms determining phenotypic heterogeneity of hepatocytes Biochemistry (Mosc.) 73 2008 367 380
-
(2008)
Biochemistry (Mosc.)
, vol.73
, pp. 367-380
-
-
Usynin, I.F.1
Panin, L.E.2
-
132
-
-
0027303993
-
Thyroid hormone and dietary carbohydrate induce different hepatic zonation of both "spot 14" and acetyl-coenzyme-A carboxylase: A novel mechanism of coregulation
-
W.B. Kinlaw, P. Tron, and L.A. Witters Thyroid hormone and dietary carbohydrate induce different hepatic zonation of both "spot 14" and acetyl-coenzyme-A carboxylase: a novel mechanism of coregulation Endocrinology 133 1993 645 650
-
(1993)
Endocrinology
, vol.133
, pp. 645-650
-
-
Kinlaw, W.B.1
Tron, P.2
Witters, L.A.3
-
133
-
-
0036732932
-
The relationship between the thyroid gland and the liver
-
R. Malik, and H. Hodgson The relationship between the thyroid gland and the liver QJM 95 2002 559 569
-
(2002)
QJM
, vol.95
, pp. 559-569
-
-
Malik, R.1
Hodgson, H.2
-
134
-
-
33845956672
-
The role of triiodothyronine-induced substrate cycles in the hepatic response to overnutrition: Thyroid hormone as an antioxidant
-
N. Grant The role of triiodothyronine-induced substrate cycles in the hepatic response to overnutrition: thyroid hormone as an antioxidant Med. Hypotheses 68 2007 641 649
-
(2007)
Med. Hypotheses
, vol.68
, pp. 641-649
-
-
Grant, N.1
-
136
-
-
0024422086
-
Dexamethasone regulates bile acid synthesis in monolayer cultures of rat hepatocytes by induction of cholesterol 7 alpha-hydroxylase
-
H.M. Princen, P. Meijer, and B. Hofstee Dexamethasone regulates bile acid synthesis in monolayer cultures of rat hepatocytes by induction of cholesterol 7 alpha-hydroxylase Biochem. J. 262 1989 341 348
-
(1989)
Biochem. J.
, vol.262
, pp. 341-348
-
-
Princen, H.M.1
Meijer, P.2
Hofstee, B.3
-
137
-
-
0037225347
-
Sex difference in hepatic peroxisome proliferator-activated receptor alpha expression: Influence of pituitary and gonadal hormones
-
M. Jalouli, L. Carlsson, C. Améen, D. Lindén, A. Ljungberg, L. Michalik, S. Edén, W. Wahli, and J. Oscarsson Sex difference in hepatic peroxisome proliferator-activated receptor alpha expression: influence of pituitary and gonadal hormones Endocrinology 144 2003 101 109
-
(2003)
Endocrinology
, vol.144
, pp. 101-109
-
-
Jalouli, M.1
Carlsson, L.2
Améen, C.3
Lindén, D.4
Ljungberg, A.5
Michalik, L.6
Edén, S.7
Wahli, W.8
Oscarsson, J.9
-
138
-
-
1542357569
-
Sexual dimorphism of rat liver gene expression: Regulatory role of growth hormone revealed by deoxyribonucleic acid microarray analysis
-
A. Ahluwalia, K.H. Clodfelter, and D.J. Waxman Sexual dimorphism of rat liver gene expression: regulatory role of growth hormone revealed by deoxyribonucleic acid microarray analysis Mol. Endocrinol. 18 2004 747 760
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 747-760
-
-
Ahluwalia, A.1
Clodfelter, K.H.2
Waxman, D.J.3
-
139
-
-
84864353016
-
Hepatic growth hormone and glucocorticoid receptor signaling in body growth, steatosis and metabolic liver cancer development
-
K.M. Mueller, M. Themanns, K. Friedbichler, J.-W. Kornfeld, H. Esterbauer, J.P. Tuckermann, and R. Moriggl Hepatic growth hormone and glucocorticoid receptor signaling in body growth, steatosis and metabolic liver cancer development Mol. Cell. Endocrinol. 361 2012 1 11
-
(2012)
Mol. Cell. Endocrinol.
, vol.361
, pp. 1-11
-
-
Mueller, K.M.1
Themanns, M.2
Friedbichler, K.3
Kornfeld, J.-W.4
Esterbauer, H.5
Tuckermann, J.P.6
Moriggl, R.7
-
141
-
-
32644436318
-
Liver triglyceride secretion and lipid oxidative metabolism are rapidly altered by leptin in vivo
-
W. Huang, N. Dedousis, A. Bandi, G.D. Lopaschuk, and R.M. O'Doherty Liver triglyceride secretion and lipid oxidative metabolism are rapidly altered by leptin in vivo Endocrinology 147 2006 1480 1487
-
(2006)
Endocrinology
, vol.147
, pp. 1480-1487
-
-
Huang, W.1
Dedousis, N.2
Bandi, A.3
Lopaschuk, G.D.4
O'Doherty, R.M.5
-
142
-
-
36348951552
-
Tissue-specific effects of central leptin on the expression of genes involved in lipid metabolism in liver and white adipose tissue
-
N. Gallardo, E. Bonzón-Kulichenko, T. Fernández-Agulló, E. Moltó, S. Gómez-Alonso, P. Blanco, J. Carrascosa, M. Ros, and A. Andrés Tissue-specific effects of central leptin on the expression of genes involved in lipid metabolism in liver and white adipose tissue Endocrinology 148 2007 5604 5610
-
(2007)
Endocrinology
, vol.148
, pp. 5604-5610
-
-
Gallardo, N.1
Bonzón-Kulichenko, E.2
Fernández-Agulló, T.3
Moltó, E.4
Gómez-Alonso, S.5
Blanco, P.6
Carrascosa, J.7
Ros, M.8
Andrés, A.9
-
143
-
-
54349124808
-
Leptin regulates peripheral lipid metabolism primarily through central effects on food intake
-
X. Prieur, Y.C.L. Tung, J.L. Griffin, I.S. Farooqi, S. O'Rahilly, and A.P. Coll Leptin regulates peripheral lipid metabolism primarily through central effects on food intake Endocrinology 149 2008 5432 5439
-
(2008)
Endocrinology
, vol.149
, pp. 5432-5439
-
-
Prieur, X.1
Tung, Y.C.L.2
Griffin, J.L.3
Farooqi, I.S.4
O'Rahilly, S.5
Coll, A.P.6
-
145
-
-
12144290385
-
Female-predominant expression of fatty acid translocase/CD36 in rat and human liver
-
N. Ståhlberg, E. Rico-Bautista, R.M. Fisher, X. Wu, L. Cheung, A. Flores-Morales, G. Tybring, G. Norstedt, and P. Tollet-Egnell Female-predominant expression of fatty acid translocase/CD36 in rat and human liver Endocrinology 145 2004 1972 1979
-
(2004)
Endocrinology
, vol.145
, pp. 1972-1979
-
-
Ståhlberg, N.1
Rico-Bautista, E.2
Fisher, R.M.3
Wu, X.4
Cheung, L.5
Flores-Morales, A.6
Tybring, G.7
Norstedt, G.8
Tollet-Egnell, P.9
-
146
-
-
33746681910
-
Tissue-specific expression and regulation of sexually dimorphic genes in mice
-
X. Yang, E.E. Schadt, S. Wang, H. Wang, A.P. Arnold, L. Ingram-Drake, T.A. Drake, and A.J. Lusis Tissue-specific expression and regulation of sexually dimorphic genes in mice Genome Res. 16 2006 995 1004
-
(2006)
Genome Res.
, vol.16
, pp. 995-1004
-
-
Yang, X.1
Schadt, E.E.2
Wang, S.3
Wang, H.4
Arnold, A.P.5
Ingram-Drake, L.6
Drake, T.A.7
Lusis, A.J.8
-
147
-
-
41549158345
-
Sex-differential expression of metabolism-related genes in response to a high-fat diet
-
T. Priego, J. Sánchez, C. Picó, and A. Palou Sex-differential expression of metabolism-related genes in response to a high-fat diet Obesity (Silver Spring) 16 2008 819 826
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 819-826
-
-
Priego, T.1
Sánchez, J.2
Picó, C.3
Palou, A.4
-
148
-
-
0017104187
-
Comparison of metabolism of free fatty acid by isolated perfused livers from male and female rats
-
C. Soler-Argilaga, and M. Heimberg Comparison of metabolism of free fatty acid by isolated perfused livers from male and female rats J. Lipid Res. 17 1976 605 615
-
(1976)
J. Lipid Res.
, vol.17
, pp. 605-615
-
-
Soler-Argilaga, C.1
Heimberg, M.2
-
149
-
-
2642651083
-
Hepatic zonation of the induction of cytochrome P450 IVA, peroxisomal lipid beta-oxidation enzymes and peroxisome proliferation in rats treated with dehydroepiandrosterone (DHEA). Evidence of distinct zonal and sex-specific differences
-
K. Beier, A. Völkl, C. Metzger, D. Mayer, P. Bannasch, and H.D. Fahimi Hepatic zonation of the induction of cytochrome P450 IVA, peroxisomal lipid beta-oxidation enzymes and peroxisome proliferation in rats treated with dehydroepiandrosterone (DHEA). Evidence of distinct zonal and sex-specific differences Carcinogenesis 18 1997 1491 1498
-
(1997)
Carcinogenesis
, vol.18
, pp. 1491-1498
-
-
Beier, K.1
Völkl, A.2
Metzger, C.3
Mayer, D.4
Bannasch, P.5
Fahimi, H.D.6
-
150
-
-
0023243882
-
Sex differences in the control of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase. Interaction of estrogen, testosterone and insulin in the regulation of enzyme levels in vivo and in cultured hepatocytes
-
R.J. Hansen, and K. Jungermann Sex differences in the control of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase. Interaction of estrogen, testosterone and insulin in the regulation of enzyme levels in vivo and in cultured hepatocytes Biol. Chem. Hoppe Seyler 368 1987 955 962
-
(1987)
Biol. Chem. Hoppe Seyler
, vol.368
, pp. 955-962
-
-
Hansen, R.J.1
Jungermann, K.2
-
151
-
-
0032498122
-
Periportal localization of glucagon receptor mRNA in rat liver and regulation of its expression by glucose and oxygen in hepatocyte cultures
-
A. Krones, T. Kietzmann, and K. Jungermann Periportal localization of glucagon receptor mRNA in rat liver and regulation of its expression by glucose and oxygen in hepatocyte cultures FEBS Lett. 421 1998 136 140
-
(1998)
FEBS Lett.
, vol.421
, pp. 136-140
-
-
Krones, A.1
Kietzmann, T.2
Jungermann, K.3
-
152
-
-
0344859905
-
Zonal expression of the thyroid hormone receptor alpha isoforms in rodent liver
-
B. Zandieh-Doulabi, E. Dop, M. Schneiders, M.P. Schiphorst, A. Mansen, B. Vennström, C.D. Dijkstra, O. Bakker, and W.M. Wiersinga Zonal expression of the thyroid hormone receptor alpha isoforms in rodent liver J. Endocrinol. 179 2003 379 385
-
(2003)
J. Endocrinol.
, vol.179
, pp. 379-385
-
-
Zandieh-Doulabi, B.1
Dop, E.2
Schneiders, M.3
Schiphorst, M.P.4
Mansen, A.5
Vennström, B.6
Dijkstra, C.D.7
Bakker, O.8
Wiersinga, W.M.9
-
153
-
-
0011820113
-
Liver structure and innervation
-
D.G. Thurman, F.C. Kauffman, K. Jungermann, John Wiley & Sons New York
-
D. Sasse Liver structure and innervation D.G. Thurman, F.C. Kauffman, K. Jungermann, Regulation of Hepatic Metabolism 1986 John Wiley & Sons New York 3 25
-
(1986)
Regulation of Hepatic Metabolism
, pp. 3-25
-
-
Sasse, D.1
-
154
-
-
84879292581
-
Hepatic nervous system and neurobiology of the liver
-
K.J. Jensen, G. Alpini, and S. Glaser Hepatic nervous system and neurobiology of the liver Compr. Physiol. 3 2013 655 665
-
(2013)
Compr. Physiol.
, vol.3
, pp. 655-665
-
-
Jensen, K.J.1
Alpini, G.2
Glaser, S.3
-
155
-
-
84987895210
-
Role of intrahepatic innervation in regulating the activity of liver cells
-
L.A.M. Streba, C.C. Vere, A.G. Ionescu, C.T. Streba, and I. Rogoveanu Role of intrahepatic innervation in regulating the activity of liver cells World J. Hepatol. 6 2014 137 143
-
(2014)
World J. Hepatol.
, vol.6
, pp. 137-143
-
-
Streba, L.A.M.1
Vere, C.C.2
Ionescu, A.G.3
Streba, C.T.4
Rogoveanu, I.5
-
156
-
-
0023320654
-
Mechanism of action of sympathetic hepatic nerves on carbohydrate metabolism in perfused rat liver
-
K. Beckh, U. Beuers, R. Engelhardt, and K. Jungermann Mechanism of action of sympathetic hepatic nerves on carbohydrate metabolism in perfused rat liver Biol. Chem. Hoppe Seyler 368 1987 379 386
-
(1987)
Biol. Chem. Hoppe Seyler
, vol.368
, pp. 379-386
-
-
Beckh, K.1
Beuers, U.2
Engelhardt, R.3
Jungermann, K.4
-
157
-
-
0018800376
-
Isolation and characterization of gap junctions from rat liver
-
E.L. Hertzberg, and N.B. Gilula Isolation and characterization of gap junctions from rat liver J. Biol. Chem. 254 1979 2138 2147
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 2138-2147
-
-
Hertzberg, E.L.1
Gilula, N.B.2
-
158
-
-
0026573508
-
Signal propagation via gap junctions, a key step in the regulation of liver metabolism by the sympathetic hepatic nerves
-
F.G. Seseke, A. Gardemann, and K. Jungermann Signal propagation via gap junctions, a key step in the regulation of liver metabolism by the sympathetic hepatic nerves FEBS Lett. 301 1992 265 270
-
(1992)
FEBS Lett.
, vol.301
, pp. 265-270
-
-
Seseke, F.G.1
Gardemann, A.2
Jungermann, K.3
-
160
-
-
0029856242
-
Demonstration of noradrenaline-immunoreactive nerve fibres in the liver
-
Y. Fukuda, M. Imoto, Y. Koyama, Y. Miyazawa, and T. Hayakawa Demonstration of noradrenaline-immunoreactive nerve fibres in the liver J. Int. Med. Res. 24 1996 466 472
-
(1996)
J. Int. Med. Res.
, vol.24
, pp. 466-472
-
-
Fukuda, Y.1
Imoto, M.2
Koyama, Y.3
Miyazawa, Y.4
Hayakawa, T.5
-
162
-
-
0021008402
-
Afferent and efferent neural roles in liver function
-
W.W. Lautt Afferent and efferent neural roles in liver function Prog. Neurobiol. 21 1983 323 348
-
(1983)
Prog. Neurobiol.
, vol.21
, pp. 323-348
-
-
Lautt, W.W.1
-
163
-
-
0021140677
-
Regulation of oxygen consumption in perfused rat liver: Decrease by alpha-sympathetic nerve stimulation and increase by the alpha-agonist phenylephrine
-
K. Beckh, H. Hartmann, K. Jungermann, and R. Scholz Regulation of oxygen consumption in perfused rat liver: decrease by alpha-sympathetic nerve stimulation and increase by the alpha-agonist phenylephrine Pflugers Arch. 401 1984 104 106
-
(1984)
Pflugers Arch.
, vol.401
, pp. 104-106
-
-
Beckh, K.1
Hartmann, H.2
Jungermann, K.3
Scholz, R.4
-
164
-
-
0031557093
-
Role of central neural mechanisms in the regulation of hepatic glucose metabolism
-
K. Nonogaki, and A. Iguchi Role of central neural mechanisms in the regulation of hepatic glucose metabolism Life Sci. 60 1997 797 807
-
(1997)
Life Sci.
, vol.60
, pp. 797-807
-
-
Nonogaki, K.1
Iguchi, A.2
-
165
-
-
0024469988
-
Modulation of the sympathetic nerve action on carbohydrate and ketone body metabolism by fatty acids, glucagon und insulin in perfused rat liver
-
J. Küster, U. Beuers, and K. Jungermann Modulation of the sympathetic nerve action on carbohydrate and ketone body metabolism by fatty acids, glucagon und insulin in perfused rat liver Biol. Chem. Hoppe Seyler 370 1989 1035 1044
-
(1989)
Biol. Chem. Hoppe Seyler
, vol.370
, pp. 1035-1044
-
-
Küster, J.1
Beuers, U.2
Jungermann, K.3
-
166
-
-
0027520784
-
The regulation of mitochondrial fatty acid oxidation and hepatic gene expression by catecholamine
-
R.A. Barke, P.S. Brady, and L.J. Brady The regulation of mitochondrial fatty acid oxidation and hepatic gene expression by catecholamine J. Surg. Res. 54 1993 95 101
-
(1993)
J. Surg. Res.
, vol.54
, pp. 95-101
-
-
Barke, R.A.1
Brady, P.S.2
Brady, L.J.3
-
167
-
-
1642454875
-
Liver denervation affects hepatocyte mitochondrial fatty acid transport capacity
-
F.R. Carreño, and M.C.L. Seelaender Liver denervation affects hepatocyte mitochondrial fatty acid transport capacity Cell Biochem. Funct. 22 2004 9 17
-
(2004)
Cell Biochem. Funct.
, vol.22
, pp. 9-17
-
-
Carreño, F.R.1
Seelaender, M.C.L.2
-
168
-
-
0029820881
-
Differential effects of physiological versus pathophysiological plasma concentrations of epinephrine and norepinephrine on ketone body metabolism and hepatic portal blood flow in man
-
A.J. Krentz, D. Freedman, R. Greene, M. McKinley, P.J. Boyle, and D.S. Schade Differential effects of physiological versus pathophysiological plasma concentrations of epinephrine and norepinephrine on ketone body metabolism and hepatic portal blood flow in man Metab. Clin. Exp. 45 1996 1214 1220
-
(1996)
Metab. Clin. Exp.
, vol.45
, pp. 1214-1220
-
-
Krentz, A.J.1
Freedman, D.2
Greene, R.3
McKinley, M.4
Boyle, P.J.5
Schade, D.S.6
-
169
-
-
0031886364
-
Noradrenaline and ATP decrease the secretion of triglyceride and apoprotein B from perfused rat liver
-
T. Yamauchi, M. Iwai, N. Kobayashi, and T. Shimazu Noradrenaline and ATP decrease the secretion of triglyceride and apoprotein B from perfused rat liver Pflugers Arch. 435 1998 368 374
-
(1998)
Pflugers Arch.
, vol.435
, pp. 368-374
-
-
Yamauchi, T.1
Iwai, M.2
Kobayashi, N.3
Shimazu, T.4
-
170
-
-
0030844035
-
Role and mechanisms of action of acetylcholine in the regulation of rat cholangiocyte secretory functions
-
D. Alvaro, G. Alpini, A.M. Jezequel, C. Bassotti, C. Francia, F. Fraioli, R. Romeo, L. Marucci, G. Le Sage, S.S. Glaser, and A. Benedetti Role and mechanisms of action of acetylcholine in the regulation of rat cholangiocyte secretory functions J. Clin. Invest. 100 1997 1349 1362
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 1349-1362
-
-
Alvaro, D.1
Alpini, G.2
Jezequel, A.M.3
Bassotti, C.4
Francia, C.5
Fraioli, F.6
Romeo, R.7
Marucci, L.8
Le Sage, G.9
Glaser, S.S.10
Benedetti, A.11
-
171
-
-
0032990637
-
Cholinergic system modulates growth, apoptosis, and secretion of cholangiocytes from bile duct-ligated rats
-
G. LeSage, D. Alvaro, A. Benedetti, S. Glaser, L. Marucci, L. Baiocchi, W. Eisel, A. Caligiuri, J.L. Phinizy, R. Rodgers, H. Francis, and G. Alpini Cholinergic system modulates growth, apoptosis, and secretion of cholangiocytes from bile duct-ligated rats Gastroenterology 117 1999 191 199
-
(1999)
Gastroenterology
, vol.117
, pp. 191-199
-
-
Lesage, G.1
Alvaro, D.2
Benedetti, A.3
Glaser, S.4
Marucci, L.5
Baiocchi, L.6
Eisel, W.7
Caligiuri, A.8
Phinizy, J.L.9
Rodgers, R.10
Francis, H.11
Alpini, G.12
-
174
-
-
79958146175
-
Role of Wnt/beta-catenin signaling in liver metabolism and cancer
-
S.P.S. Monga Role of Wnt/beta-catenin signaling in liver metabolism and cancer Int. J. Biochem. Cell Biol. 43 2011 1021 1029
-
(2011)
Int. J. Biochem. Cell Biol.
, vol.43
, pp. 1021-1029
-
-
Monga, S.P.S.1
-
175
-
-
78651429899
-
Transcription dynamics in a physiological process: Beta-catenin signaling directs liver metabolic zonation
-
C. Torre, C. Perret, and S. Colnot Transcription dynamics in a physiological process: beta-catenin signaling directs liver metabolic zonation Int. J. Biochem. Cell Biol. 43 2011 271 278
-
(2011)
Int. J. Biochem. Cell Biol.
, vol.43
, pp. 271-278
-
-
Torre, C.1
Perret, C.2
Colnot, S.3
-
176
-
-
84875614093
-
Hedgehog signalling pathway in adult liver: A major new player in hepatocyte metabolism and zonation?
-
M. Matz-Soja, A. Hovhannisyan, and R. Gebhardt Hedgehog signalling pathway in adult liver: a major new player in hepatocyte metabolism and zonation? Med. Hypotheses 80 2013 589 594
-
(2013)
Med. Hypotheses
, vol.80
, pp. 589-594
-
-
Matz-Soja, M.1
Hovhannisyan, A.2
Gebhardt, R.3
-
177
-
-
0037191930
-
New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism
-
A. Cadoret, C. Ovejero, B. Terris, E. Souil, L. Lévy, W.H. Lamers, J. Kitajewski, A. Kahn, and C. Perret New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism Oncogene 21 2002 8293 8301
-
(2002)
Oncogene
, vol.21
, pp. 8293-8301
-
-
Cadoret, A.1
Ovejero, C.2
Terris, B.3
Souil, E.4
Lévy, L.5
Lamers, W.H.6
Kitajewski, J.7
Kahn, A.8
Perret, C.9
-
178
-
-
0037108681
-
Overexpression of glutamine synthetase is associated with beta-catenin - Mutations in mouse liver tumors during promotion of hepatocarcinogenesis by phenobarbital
-
S. Loeppen, D. Schneider, F. Gaunitz, R. Gebhardt, R. Kurek, A. Buchmann, and M. Schwarz Overexpression of glutamine synthetase is associated with beta-catenin - mutations in mouse liver tumors during promotion of hepatocarcinogenesis by phenobarbital Cancer Res. 62 2002 5685 5688
-
(2002)
Cancer Res.
, vol.62
, pp. 5685-5688
-
-
Loeppen, S.1
Schneider, D.2
Gaunitz, F.3
Gebhardt, R.4
Kurek, R.5
Buchmann, A.6
Schwarz, M.7
-
179
-
-
84864331333
-
Dynamic network reconstruction from gene expression data describing the effect of LiCl stimulation on hepatocytes
-
S. Zellmer, W. Schmidt-Heck, F. Gaunitz, A. Baldysiak-Figiel, R. Guthke, and R. Gebhardt Dynamic network reconstruction from gene expression data describing the effect of LiCl stimulation on hepatocytes J. Integr. Bioinform. 2 2005 15
-
(2005)
J. Integr. Bioinform.
, vol.2
, pp. 15
-
-
Zellmer, S.1
Schmidt-Heck, W.2
Gaunitz, F.3
Baldysiak-Figiel, A.4
Guthke, R.5
Gebhardt, R.6
-
180
-
-
33750819403
-
The Wnt/beta-catenin pathway: Master regulator of liver zonation?
-
Z.D. Burke, and D. Tosh The Wnt/beta-catenin pathway: master regulator of liver zonation? Bioessays 28 2006 1072 1077
-
(2006)
Bioessays
, vol.28
, pp. 1072-1077
-
-
Burke, Z.D.1
Tosh, D.2
-
181
-
-
66449086571
-
Liver zonation occurs through a beta-catenin-dependent, c-Myc-independent mechanism
-
Z.D. Burke, K.R. Reed, T.J. Phesse, O.J. Sansom, A.R. Clarke, and D. Tosh Liver zonation occurs through a beta-catenin-dependent, c-Myc-independent mechanism Gastroenterology 136 2009 2316 2324
-
(2009)
Gastroenterology
, vol.136
, pp. 2316-2324
-
-
Burke, Z.D.1
Reed, K.R.2
Phesse, T.J.3
Sansom, O.J.4
Clarke, A.R.5
Tosh, D.6
-
182
-
-
65549136561
-
Regulation of cytochrome P450 expression by Ras- and beta-catenin-dependent signaling
-
A. Braeuning Regulation of cytochrome P450 expression by Ras- and beta-catenin-dependent signaling Curr. Drug Metab. 10 2009 138 158
-
(2009)
Curr. Drug Metab.
, vol.10
, pp. 138-158
-
-
Braeuning, A.1
-
183
-
-
33744495398
-
Apc tumor suppressor gene is the "zonation-keeper" of mouse liver
-
S. Benhamouche, T. Decaens, C. Godard, R. Chambrey, D.S. Rickman, C. Moinard, M. Vasseur-Cognet, C.J. Kuo, A. Kahn, C. Perret, and S. Colnot Apc tumor suppressor gene is the "zonation-keeper" of mouse liver Dev. Cell 10 2006 759 770
-
(2006)
Dev. Cell
, vol.10
, pp. 759-770
-
-
Benhamouche, S.1
Decaens, T.2
Godard, C.3
Chambrey, R.4
Rickman, D.S.5
Moinard, C.6
Vasseur-Cognet, M.7
Kuo, C.J.8
Kahn, A.9
Perret, C.10
Colnot, S.11
-
184
-
-
33645989449
-
Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice
-
S. Sekine, B.Y.-A. Lan, M. Bedolli, S. Feng, and M. Hebrok Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice Hepatology 43 2006 817 825
-
(2006)
Hepatology
, vol.43
, pp. 817-825
-
-
Sekine, S.1
Lan, B.Y.-A.2
Bedolli, M.3
Feng, S.4
Hebrok, M.5
-
185
-
-
33750726092
-
Conditional deletion of beta-catenin reveals its role in liver growth and regeneration
-
X. Tan, J. Behari, B. Cieply, G.K. Michalopoulos, and S.P.S. Monga Conditional deletion of beta-catenin reveals its role in liver growth and regeneration Gastroenterology 131 2006 1561 1572
-
(2006)
Gastroenterology
, vol.131
, pp. 1561-1572
-
-
Tan, X.1
Behari, J.2
Cieply, B.3
Michalopoulos, G.K.4
Monga, S.P.S.5
-
186
-
-
84883781170
-
Modeling Wnt/beta-catenin target gene expression in APC and Wnt gradients under wild type and mutant conditions
-
U. Benary, B. Kofahl, A. Hecht, and J. Wolf Modeling Wnt/beta-catenin target gene expression in APC and Wnt gradients under wild type and mutant conditions Front. Physiol. 4 2013 21
-
(2013)
Front. Physiol.
, vol.4
, pp. 21
-
-
Benary, U.1
Kofahl, B.2
Hecht, A.3
Wolf, J.4
-
187
-
-
76149088123
-
Liver-specific beta-catenin knockout mice exhibit defective bile acid and cholesterol homeostasis and increased susceptibility to diet-induced steatohepatitis
-
J. Behari, T.-H. Yeh, L. Krauland, W. Otruba, B. Cieply, B. Hauth, U. Apte, T. Wu, R. Evans, and S.P.S. Monga Liver-specific beta-catenin knockout mice exhibit defective bile acid and cholesterol homeostasis and increased susceptibility to diet-induced steatohepatitis Am. J. Pathol. 176 2010 744 753
-
(2010)
Am. J. Pathol.
, vol.176
, pp. 744-753
-
-
Behari, J.1
Yeh, T.-H.2
Krauland, L.3
Otruba, W.4
Cieply, B.5
Hauth, B.6
Apte, U.7
Wu, T.8
Evans, R.9
Monga, S.P.S.10
-
188
-
-
34347385893
-
Cholestasis is a marker for hepatocellular carcinomas displaying beta-catenin mutations
-
V. Audard, G. Grimber, C. Elie, B. Radenen, A. Audebourg, F. Letourneur, O. Soubrane, M.-C. Vacher-Lavenu, C. Perret, C. Cavard, and B. Terris Cholestasis is a marker for hepatocellular carcinomas displaying beta-catenin mutations J. Pathol. 212 2007 345 352
-
(2007)
J. Pathol.
, vol.212
, pp. 345-352
-
-
Audard, V.1
Grimber, G.2
Elie, C.3
Radenen, B.4
Audebourg, A.5
Letourneur, F.6
Soubrane, O.7
Vacher-Lavenu, M.-C.8
Perret, C.9
Cavard, C.10
Terris, B.11
-
189
-
-
0035072875
-
Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism
-
D.Q. Shih, M. Bussen, E. Sehayek, M. Ananthanarayanan, B.L. Shneider, F.J. Suchy, S. Shefer, J.S. Bollileni, F.J. Gonzalez, J.L. Breslow, and M. Stoffel Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism Nat. Genet. 27 2001 375 382
-
(2001)
Nat. Genet.
, vol.27
, pp. 375-382
-
-
Shih, D.Q.1
Bussen, M.2
Sehayek, E.3
Ananthanarayanan, M.4
Shneider, B.L.5
Suchy, F.J.6
Shefer, S.7
Bollileni, J.S.8
Gonzalez, F.J.9
Breslow, J.L.10
Stoffel, M.11
-
190
-
-
33746483284
-
Functional interaction between peroxisome proliferator-activated receptor gamma and beta-catenin
-
J. Liu, H. Wang, Y. Zuo, and S.R. Farmer Functional interaction between peroxisome proliferator-activated receptor gamma and beta-catenin Mol. Cell. Biol. 26 2006 5827 5837
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 5827-5837
-
-
Liu, J.1
Wang, H.2
Zuo, Y.3
Farmer, S.R.4
-
191
-
-
67650954348
-
Convergence of Wnt signaling on the HNF4alpha-driven transcription in controlling liver zonation
-
M. Colletti, C. Cicchini, A. Conigliaro, L. Santangelo, T. Alonzi, E. Pasquini, M. Tripodi, and L. Amicone Convergence of Wnt signaling on the HNF4alpha-driven transcription in controlling liver zonation Gastroenterology 137 2009 660 672
-
(2009)
Gastroenterology
, vol.137
, pp. 660-672
-
-
Colletti, M.1
Cicchini, C.2
Conigliaro, A.3
Santangelo, L.4
Alonzi, T.5
Pasquini, E.6
Tripodi, M.7
Amicone, L.8
-
192
-
-
84901605165
-
T-cell factor 4 and β-catenin chromatin occupancies pattern zonal liver metabolism in mice
-
A. Gougelet, C. Torre, P. Veber, C. Sartor, L. Bachelot, P.-D. Denechaud, C. Godard, M. Moldes, A.-F. Burnol, C. Dubuquoy, B. Terris, F. Guillonneau, T. Ye, M. Schwarz, A. Braeuning, C. Perret, and S. Colnot T-cell factor 4 and β-catenin chromatin occupancies pattern zonal liver metabolism in mice Hepatology 59 2014 2344 2357
-
(2014)
Hepatology
, vol.59
, pp. 2344-2357
-
-
Gougelet, A.1
Torre, C.2
Veber, P.3
Sartor, C.4
Bachelot, L.5
Denechaud, P.-D.6
Godard, C.7
Moldes, M.8
Burnol, A.-F.9
Dubuquoy, C.10
Terris, B.11
Guillonneau, F.12
Ye, T.13
Schwarz, M.14
Braeuning, A.15
Perret, C.16
Colnot, S.17
-
193
-
-
80051481674
-
Wnt-β-catenin signaling protects against hepatic ischemia and reperfusion injury in mice
-
N. Lehwald, G.-Z. Tao, K.Y. Jang, M. Sorkin, W.T. Knoefel, and K.G. Sylvester Wnt-β-catenin signaling protects against hepatic ischemia and reperfusion injury in mice Gastroenterology 141 2011 707 718
-
(2011)
Gastroenterology
, vol.141
, pp. 707-718
-
-
Lehwald, N.1
Tao, G.-Z.2
Jang, K.Y.3
Sorkin, M.4
Knoefel, W.T.5
Sylvester, K.G.6
-
194
-
-
84865453663
-
Beta-catenin regulates hepatic mitochondrial function and energy balance in mice
-
N. Lehwald, G.-Z. Tao, K.Y. Jang, I. Papandreou, B. Liu, B. Liu, M.A. Pysz, J.K. Willmann, W.T. Knoefel, N.C. Denko, and K.G. Sylvester Beta-catenin regulates hepatic mitochondrial function and energy balance in mice Gastroenterology 143 2012 754 764
-
(2012)
Gastroenterology
, vol.143
, pp. 754-764
-
-
Lehwald, N.1
Tao, G.-Z.2
Jang, K.Y.3
Papandreou, I.4
Liu, B.5
Liu, B.6
Pysz, M.A.7
Willmann, J.K.8
Knoefel, W.T.9
Denko, N.C.10
Sylvester, K.G.11
-
195
-
-
41849086320
-
FOXO-binding partners: It takes two to tango
-
K.E. van der Vos, and P.J. Coffer FOXO-binding partners: it takes two to tango Oncogene 27 2008 2289 2299
-
(2008)
Oncogene
, vol.27
, pp. 2289-2299
-
-
Van Der Vos, K.E.1
Coffer, P.J.2
-
196
-
-
79551707018
-
Wnt signaling regulates hepatic metabolism
-
H. Liu, M.M. Fergusson, J.J. Wu, I.I. Rovira, J. Liu, O. Gavrilova, T. Lu, J. Bao, D. Han, M.N. Sack, and T. Finkel Wnt signaling regulates hepatic metabolism Sci. Signal. 4 2011 ra6
-
(2011)
Sci. Signal.
, vol.4
, pp. ra6
-
-
Liu, H.1
Fergusson, M.M.2
Wu, J.J.3
Rovira, I.I.4
Liu, J.5
Gavrilova, O.6
Lu, T.7
Bao, J.8
Han, D.9
Sack, M.N.10
Finkel, T.11
-
197
-
-
51249114496
-
The WNT signalling pathway and diabetes mellitus
-
T. Jin The WNT signalling pathway and diabetes mellitus Diabetologia 51 2008 1771 1780
-
(2008)
Diabetologia
, vol.51
, pp. 1771-1780
-
-
Jin, T.1
-
198
-
-
33745491465
-
Concomitant suppression of hyperlipidemia and intestinal polyp formation by increasing lipoprotein lipase activity in Apc-deficient mice
-
M. Mutoh, N. Niho, and K. Wakabayashi Concomitant suppression of hyperlipidemia and intestinal polyp formation by increasing lipoprotein lipase activity in Apc-deficient mice Biol. Chem. 387 2006 381 385
-
(2006)
Biol. Chem.
, vol.387
, pp. 381-385
-
-
Mutoh, M.1
Niho, N.2
Wakabayashi, K.3
-
199
-
-
84922258729
-
Hepatitis C viral proteins perturb metabolic liver zonation
-
M. Moreau, B. Rivière, S. Vegna, M. Aoun, C. Gard, J. Ramos, E. Assenat, and U. Hibner Hepatitis C viral proteins perturb metabolic liver zonation J. Hepatol. 62 2015 278 285
-
(2015)
J. Hepatol.
, vol.62
, pp. 278-285
-
-
Moreau, M.1
Rivière, B.2
Vegna, S.3
Aoun, M.4
Gard, C.5
Ramos, J.6
Assenat, E.7
Hibner, U.8
-
200
-
-
33645227117
-
Zonal gene expression in murine liver: Lessons from tumors
-
S. Hailfinger, M. Jaworski, A. Braeuning, A. Buchmann, and M. Schwarz Zonal gene expression in murine liver: lessons from tumors Hepatology 43 2006 407 414
-
(2006)
Hepatology
, vol.43
, pp. 407-414
-
-
Hailfinger, S.1
Jaworski, M.2
Braeuning, A.3
Buchmann, A.4
Schwarz, M.5
-
201
-
-
34548458190
-
Serum components and activated Ha-ras antagonize expression of perivenous marker genes stimulated by beta-catenin signaling in mouse hepatocytes
-
A. Braeuning, M. Menzel, E.-M. Kleinschnitz, N. Harada, Y. Tamai, C. Köhle, A. Buchmann, and M. Schwarz Serum components and activated Ha-ras antagonize expression of perivenous marker genes stimulated by beta-catenin signaling in mouse hepatocytes FEBS J. 274 2007 4766 4777
-
(2007)
FEBS J.
, vol.274
, pp. 4766-4777
-
-
Braeuning, A.1
Menzel, M.2
Kleinschnitz, E.-M.3
Harada, N.4
Tamai, Y.5
Köhle, C.6
Buchmann, A.7
Schwarz, M.8
-
202
-
-
84866905857
-
Modeling the seasonal adaptation of circadian clocks by changes in the network structure of the suprachiasmatic nucleus
-
C. Bodenstein, M. Gosak, S. Schuster, M. Marhl, and M. Perc Modeling the seasonal adaptation of circadian clocks by changes in the network structure of the suprachiasmatic nucleus PLoS Comput. Biol. 8 2012 e1002697
-
(2012)
PLoS Comput. Biol.
, vol.8
, pp. e1002697
-
-
Bodenstein, C.1
Gosak, M.2
Schuster, S.3
Marhl, M.4
Perc, M.5
-
203
-
-
0037194790
-
Coordination of circadian timing in mammals
-
S.M. Reppert, and D.R. Weaver Coordination of circadian timing in mammals Nature 418 2002 935 941
-
(2002)
Nature
, vol.418
, pp. 935-941
-
-
Reppert, S.M.1
Weaver, D.R.2
-
204
-
-
84860299312
-
Timing to perfection: The biology of central and peripheral circadian clocks
-
U. Albrecht Timing to perfection: the biology of central and peripheral circadian clocks Neuron 74 2012 246 260
-
(2012)
Neuron
, vol.74
, pp. 246-260
-
-
Albrecht, U.1
-
205
-
-
84863614554
-
Temperature compensation and entrainment in circadian rhythms
-
C. Bodenstein, I. Heiland, and S. Schuster Temperature compensation and entrainment in circadian rhythms Phys. Biol. 9 2012 036011
-
(2012)
Phys. Biol.
, vol.9
, pp. 036011
-
-
Bodenstein, C.1
Heiland, I.2
Schuster, S.3
-
206
-
-
0033637383
-
Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus
-
F. Damiola, N. Le Minh, N. Preitner, B. Kornmann, F. Fleury-Olela, and U. Schibler Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus Genes Dev. 14 2000 2950 2961
-
(2000)
Genes Dev.
, vol.14
, pp. 2950-2961
-
-
Damiola, F.1
Le Minh, N.2
Preitner, N.3
Kornmann, B.4
Fleury-Olela, F.5
Schibler, U.6
-
207
-
-
33749031807
-
Molecular components of the mammalian circadian clock
-
C.H. Ko, and J.S. Takahashi Molecular components of the mammalian circadian clock Hum. Mol. Genet. 15 Spec. No. 2 2006 R271 R277
-
(2006)
Hum. Mol. Genet.
, vol.15
, Issue.SPEC. NO. 2
, pp. R271-R277
-
-
Ko, C.H.1
Takahashi, J.S.2
-
208
-
-
70450239457
-
Metabolism and cancer: The circadian clock connection
-
S. Sahar, and P. Sassone-Corsi Metabolism and cancer: the circadian clock connection Nat. Rev. Cancer 9 2009 886 896
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 886-896
-
-
Sahar, S.1
Sassone-Corsi, P.2
-
209
-
-
24944460267
-
Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors
-
F. Guillaumond, H. Dardente, V. Giguère, and N. Cermakian Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors J. Biol. Rhythms 20 2005 391 403
-
(2005)
J. Biol. Rhythms
, vol.20
, pp. 391-403
-
-
Guillaumond, F.1
Dardente, H.2
Giguère, V.3
Cermakian, N.4
-
210
-
-
62849114200
-
Regulation of clock-controlled genes in mammals
-
K. Bozek, A. Relógio, S.M. Kielbasa, M. Heine, C. Dame, A. Kramer, and H. Herzel Regulation of clock-controlled genes in mammals PLoS One 4 2009 e4882
-
(2009)
PLoS One
, vol.4
, pp. e4882
-
-
Bozek, K.1
Relógio, A.2
Kielbasa, S.M.3
Heine, M.4
Dame, C.5
Kramer, A.6
Herzel, H.7
-
211
-
-
0014728140
-
Histochemical and electron microscopic changes in liver cells during the diurnal rhythm and under experimental conditions
-
C. Jerusalem, W. Eling, and P. Jap Histochemical and electron microscopic changes in liver cells during the diurnal rhythm and under experimental conditions Acta Histochem. 36 1970 168 206
-
(1970)
Acta Histochem.
, vol.36
, pp. 168-206
-
-
Jerusalem, C.1
Eling, W.2
Jap, P.3
-
212
-
-
0018131499
-
Heterogeneity of liver parenchymal cells
-
K. Jungermann, and D. Sasse Heterogeneity of liver parenchymal cells Trends Biochem. Sci. 3 1978 198 202
-
(1978)
Trends Biochem. Sci.
, vol.3
, pp. 198-202
-
-
Jungermann, K.1
Sasse, D.2
-
213
-
-
0020517217
-
Karyometric investigation on circadian rhythmic changes in the periportal and perivenous zones of the acinus of the rat liver
-
M. Schultz, and R. Hildebrand Karyometric investigation on circadian rhythmic changes in the periportal and perivenous zones of the acinus of the rat liver Cell Tissue Res. 231 1983 643 654
-
(1983)
Cell Tissue Res.
, vol.231
, pp. 643-654
-
-
Schultz, M.1
Hildebrand, R.2
-
214
-
-
18444414586
-
Coordinated transcription of key pathways in the mouse by the circadian clock
-
S. Panda, M.P. Antoch, B.H. Miller, A.I. Su, A.B. Schook, M. Straume, P.G. Schultz, S.A. Kay, J.S. Takahashi, and J.B. Hogenesch Coordinated transcription of key pathways in the mouse by the circadian clock Cell 109 2002 307 320
-
(2002)
Cell
, vol.109
, pp. 307-320
-
-
Panda, S.1
Antoch, M.P.2
Miller, B.H.3
Su, A.I.4
Schook, A.B.5
Straume, M.6
Schultz, P.G.7
Kay, S.A.8
Takahashi, J.S.9
Hogenesch, J.B.10
-
215
-
-
84857124907
-
The human circadian metabolome
-
R. Dallmann, A.U. Viola, L. Tarokh, C. Cajochen, and S.A. Brown The human circadian metabolome Proc. Natl. Acad. Sci. U. S. A. 109 2012 2625 2629
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 2625-2629
-
-
Dallmann, R.1
Viola, A.U.2
Tarokh, L.3
Cajochen, C.4
Brown, S.A.5
-
216
-
-
79551534130
-
Crosstalk between components of circadian and metabolic cycles in mammals
-
G. Asher, and U. Schibler Crosstalk between components of circadian and metabolic cycles in mammals Cell Metab. 13 2011 125 137
-
(2011)
Cell Metab.
, vol.13
, pp. 125-137
-
-
Asher, G.1
Schibler, U.2
-
217
-
-
0035976638
-
Nuclear receptors and lipid physiology: Opening the X-files
-
A. Chawla, J.J. Repa, R.M. Evans, and D.J. Mangelsdorf Nuclear receptors and lipid physiology: opening the X-files Science 294 2001 1866 1870
-
(2001)
Science
, vol.294
, pp. 1866-1870
-
-
Chawla, A.1
Repa, J.J.2
Evans, R.M.3
Mangelsdorf, D.J.4
-
218
-
-
15944382729
-
CLOCK is involved in the circadian transactivation of peroxisome-proliferator-activated receptor alpha (PPARalpha) in mice
-
K. Oishi, H. Shirai, and N. Ishida CLOCK is involved in the circadian transactivation of peroxisome-proliferator-activated receptor alpha (PPARalpha) in mice Biochem. J. 386 2005 575 581
-
(2005)
Biochem. J.
, vol.386
, pp. 575-581
-
-
Oishi, K.1
Shirai, H.2
Ishida, N.3
-
219
-
-
33845564531
-
Elovl3: A model gene to dissect homeostatic links between the circadian clock and nutritional status
-
A. Anzulovich, A. Mir, M. Brewer, G. Ferreyra, C. Vinson, and R. Baler Elovl3: a model gene to dissect homeostatic links between the circadian clock and nutritional status J. Lipid Res. 47 2006 2690 2700
-
(2006)
J. Lipid Res.
, vol.47
, pp. 2690-2700
-
-
Anzulovich, A.1
Mir, A.2
Brewer, M.3
Ferreyra, G.4
Vinson, C.5
Baler, R.6
-
220
-
-
84860291442
-
Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists
-
L.A. Solt, Y. Wang, S. Banerjee, T. Hughes, D.J. Kojetin, T. Lundasen, Y. Shin, J. Liu, M.D. Cameron, R. Noel, S.-H. Yoo, J.S. Takahashi, A.A. Butler, T.M. Kamenecka, and T.P. Burris Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists Nature 485 2012 62 68
-
(2012)
Nature
, vol.485
, pp. 62-68
-
-
Solt, L.A.1
Wang, Y.2
Banerjee, S.3
Hughes, T.4
Kojetin, D.J.5
Lundasen, T.6
Shin, Y.7
Liu, J.8
Cameron, M.D.9
Noel, R.10
Yoo, S.-H.11
Takahashi, J.S.12
Butler, A.A.13
Kamenecka, T.M.14
Burris, T.P.15
-
221
-
-
78049437320
-
PER2 controls lipid metabolism by direct regulation of PPARγ
-
B. Grimaldi, M.M. Bellet, S. Katada, G. Astarita, J. Hirayama, R.H. Amin, J.G. Granneman, D. Piomelli, T. Leff, and P. Sassone-Corsi PER2 controls lipid metabolism by direct regulation of PPARγ Cell Metab. 12 2010 509 520
-
(2010)
Cell Metab.
, vol.12
, pp. 509-520
-
-
Grimaldi, B.1
Bellet, M.M.2
Katada, S.3
Astarita, G.4
Hirayama, J.5
Amin, R.H.6
Granneman, J.G.7
Piomelli, D.8
Leff, T.9
Sassone-Corsi, P.10
-
222
-
-
84873382813
-
Chronic mild stress alters circadian expressions of molecular clock genes in the liver
-
K. Takahashi, T. Yamada, S. Tsukita, K. Kaneko, Y. Shirai, Y. Munakata, Y. Ishigaki, J. Imai, K. Uno, Y. Hasegawa, S. Sawada, Y. Oka, and H. Katagiri Chronic mild stress alters circadian expressions of molecular clock genes in the liver Am. J. Physiol. Endocrinol. Metab. 304 2013 E301 E309
-
(2013)
Am. J. Physiol. Endocrinol. Metab.
, vol.304
, pp. E301-E309
-
-
Takahashi, K.1
Yamada, T.2
Tsukita, S.3
Kaneko, K.4
Shirai, Y.5
Munakata, Y.6
Ishigaki, Y.7
Imai, J.8
Uno, K.9
Hasegawa, Y.10
Sawada, S.11
Oka, Y.12
Katagiri, H.13
-
223
-
-
0025982991
-
Diurnal variations of lipogenic enzyme mRNA quantities in rat liver
-
H. Fukuda, and N. Iritani Diurnal variations of lipogenic enzyme mRNA quantities in rat liver Biochim. Biophys. Acta 1086 1991 261 264
-
(1991)
Biochim. Biophys. Acta
, vol.1086
, pp. 261-264
-
-
Fukuda, H.1
Iritani, N.2
-
224
-
-
44149128885
-
Steroid hormones control circadian Elovl3 expression in mouse liver
-
A. Brolinson, S. Fourcade, A. Jakobsson, A. Pujol, and A. Jacobsson Steroid hormones control circadian Elovl3 expression in mouse liver Endocrinology 149 2008 3158 3166
-
(2008)
Endocrinology
, vol.149
, pp. 3158-3166
-
-
Brolinson, A.1
Fourcade, S.2
Jakobsson, A.3
Pujol, A.4
Jacobsson, A.5
-
225
-
-
33646561211
-
Genome-wide expression analysis reveals 100 adrenal gland-dependent circadian genes in the mouse liver
-
K. Oishi, N. Amagai, H. Shirai, K. Kadota, N. Ohkura, and N. Ishida Genome-wide expression analysis reveals 100 adrenal gland-dependent circadian genes in the mouse liver DNA Res. 12 2005 191 202
-
(2005)
DNA Res.
, vol.12
, pp. 191-202
-
-
Oishi, K.1
Amagai, N.2
Shirai, H.3
Kadota, K.4
Ohkura, N.5
Ishida, N.6
-
226
-
-
0028693582
-
Lipogenic activities in rat liver are subjected to circadian rhythms
-
R. Zardoya, A. Diez, M.C. Serradilla, J.A. Madrid, J.M. Bautista, and A. Garrido-Pertierra Lipogenic activities in rat liver are subjected to circadian rhythms Rev. Esp. Fisiol. 50 1994 239 244
-
(1994)
Rev. Esp. Fisiol.
, vol.50
, pp. 239-244
-
-
Zardoya, R.1
Diez, A.2
Serradilla, M.C.3
Madrid, J.A.4
Bautista, J.M.5
Garrido-Pertierra, A.6
-
227
-
-
0023035866
-
Circadian changes in serum and liver metabolites and liver lipogenic enzymes in ad libitum- and meal-fed, lean and obese Zucker rats
-
S. Lanza-Jacoby, N.R. Stevenson, and M.L. Kaplan Circadian changes in serum and liver metabolites and liver lipogenic enzymes in ad libitum- and meal-fed, lean and obese Zucker rats J. Nutr. 116 1986 1798 1809
-
(1986)
J. Nutr.
, vol.116
, pp. 1798-1809
-
-
Lanza-Jacoby, S.1
Stevenson, N.R.2
Kaplan, M.L.3
-
228
-
-
0017042953
-
The circadian rhythm of synthesis and catabolism of cholesterol
-
D. Mayer The circadian rhythm of synthesis and catabolism of cholesterol Arch. Toxicol. 36 1976 267 276
-
(1976)
Arch. Toxicol.
, vol.36
, pp. 267-276
-
-
Mayer, D.1
-
229
-
-
0029017486
-
Different hepatocytes express the cholesterol 7 alpha-hydroxylase gene during its circadian modulation in vivo
-
C.M. Berkowitz, C.S. Shen, B.M. Bilir, E. Guibert, and J.J. Gumucio Different hepatocytes express the cholesterol 7 alpha-hydroxylase gene during its circadian modulation in vivo Hepatology 21 1995 1658 1667
-
(1995)
Hepatology
, vol.21
, pp. 1658-1667
-
-
Berkowitz, C.M.1
Shen, C.S.2
Bilir, B.M.3
Guibert, E.4
Gumucio, J.J.5
-
230
-
-
0032577192
-
The spontaneous induction of glutamine synthetase in pig hepatocytes cocultured with RL-ET-14 cells is completely inhibited by trijodothyronine and okadaic acid
-
R. Gebhardt, M. Schuler, and D. Schörner The spontaneous induction of glutamine synthetase in pig hepatocytes cocultured with RL-ET-14 cells is completely inhibited by trijodothyronine and okadaic acid Biochem. Biophys. Res. Commun. 246 1998 895 898
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.246
, pp. 895-898
-
-
Gebhardt, R.1
Schuler, M.2
Schörner, D.3
-
231
-
-
0025738757
-
The dynamics of the expression of C/EBP mRNA in the adult rat liver lobulus qualifies it as a pericentral mRNA
-
A.F. Moorman, M.J. van den Hoff, P.A. de Boer, R. Charles, and W.H. Lamers The dynamics of the expression of C/EBP mRNA in the adult rat liver lobulus qualifies it as a pericentral mRNA FEBS Lett. 288 1991 133 137
-
(1991)
FEBS Lett.
, vol.288
, pp. 133-137
-
-
Moorman, A.F.1
Van Den Hoff, M.J.2
De Boer, P.A.3
Charles, R.4
Lamers, W.H.5
-
232
-
-
0027530626
-
Relative roles of CCAAT/enhancer-binding protein beta and cAMP regulatory element-binding protein in controlling transcription of the gene for phosphoenolpyruvate carboxykinase (GTP)
-
E.A. Park, A.L. Gurney, S.E. Nizielski, P. Hakimi, Z. Cao, A. Moorman, and R.W. Hanson Relative roles of CCAAT/enhancer-binding protein beta and cAMP regulatory element-binding protein in controlling transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) J. Biol. Chem. 268 1993 613 619
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 613-619
-
-
Park, E.A.1
Gurney, A.L.2
Nizielski, S.E.3
Hakimi, P.4
Cao, Z.5
Moorman, A.6
Hanson, R.W.7
-
233
-
-
0030808426
-
Zonal distribution of transcripts of four hepatic transcription factors in the mature rat liver
-
K.O. Lindros, T. Oinonen, J. Issakainen, P. Nagy, and S.S. Thorgeirsson Zonal distribution of transcripts of four hepatic transcription factors in the mature rat liver Cell Biol. Toxicol. 13 1997 257 262
-
(1997)
Cell Biol. Toxicol.
, vol.13
, pp. 257-262
-
-
Lindros, K.O.1
Oinonen, T.2
Issakainen, J.3
Nagy, P.4
Thorgeirsson, S.S.5
-
234
-
-
0015047607
-
Simulation of the Krebs cycle and closely related metabolism in perfused rat liver. I. Construction of a model
-
D. Garfinkel Simulation of the Krebs cycle and closely related metabolism in perfused rat liver. I. Construction of a model Comput. Biomed. Res. 4 1971 1 17
-
(1971)
Comput. Biomed. Res.
, vol.4
, pp. 1-17
-
-
Garfinkel, D.1
-
235
-
-
0015045962
-
Simulation of the Krebs cycle and closely related metabolism in perfused rat liver. II. Properties of the model
-
D. Garfinkel Simulation of the Krebs cycle and closely related metabolism in perfused rat liver. II. Properties of the model Comput. Biomed. Res. 4 1971 18 42
-
(1971)
Comput. Biomed. Res.
, vol.4
, pp. 18-42
-
-
Garfinkel, D.1
-
236
-
-
37149002215
-
A computer model of gluconeogenesis and lipid metabolism in the perfused liver
-
E. Chalhoub, R.W. Hanson, and J.M. Belovich A computer model of gluconeogenesis and lipid metabolism in the perfused liver Am. J. Physiol. Endocrinol. Metab. 293 2007 E1676 E1686
-
(2007)
Am. J. Physiol. Endocrinol. Metab.
, vol.293
, pp. E1676-E1686
-
-
Chalhoub, E.1
Hanson, R.W.2
Belovich, J.M.3
-
237
-
-
65349091867
-
A mathematical model of liver metabolism: From steady state to dynamic
-
D. Calvetti, A. Kuceyeski, and E. Somersalo A mathematical model of liver metabolism: from steady state to dynamic J. Phys. Conf. Ser. 124 2008 012012
-
(2008)
J. Phys. Conf. Ser.
, vol.124
, pp. 012012
-
-
Calvetti, D.1
Kuceyeski, A.2
Somersalo, E.3
-
238
-
-
79960955664
-
In silico evidence for gluconeogenesis from fatty acids in humans
-
C. Kaleta, L.F. de Figueiredo, S. Werner, R. Guthke, M. Ristow, and S. Schuster In silico evidence for gluconeogenesis from fatty acids in humans PLoS Comput. Biol. 7 2011 e1002116
-
(2011)
PLoS Comput. Biol.
, vol.7
, pp. e1002116
-
-
Kaleta, C.1
De Figueiredo, L.F.2
Werner, S.3
Guthke, R.4
Ristow, M.5
Schuster, S.6
-
239
-
-
77956407882
-
HepatoNet1: A comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology
-
C. Gille, C. Bölling, A. Hoppe, S. Bulik, S. Hoffmann, K. Hübner, A. Karlstädt, R. Ganeshan, M. König, K. Rother, M. Weidlich, J. Behre, and H.-G. Holzhütter HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology Mol. Syst. Biol. 6 2010 411
-
(2010)
Mol. Syst. Biol.
, vol.6
, pp. 411
-
-
Gille, C.1
Bölling, C.2
Hoppe, A.3
Bulik, S.4
Hoffmann, S.5
Hübner, K.6
Karlstädt, A.7
Ganeshan, R.8
König, M.9
Rother, K.10
Weidlich, M.11
Behre, J.12
Holzhütter, H.-G.13
-
240
-
-
84923581080
-
A 2-compartment model of glutamine and ammonia metabolism in liver tissue
-
S. Toepfer, S. Zellmer, D. Driesch, D. Woetzel, R. Guthke, R. Gebhardt, and M. Pfaff A 2-compartment model of glutamine and ammonia metabolism in liver tissue Proceed. 52nd International Scientific Colloquium, Ilmenau 2007 107 112
-
(2007)
Proceed. 52nd International Scientific Colloquium, Ilmenau
, pp. 107-112
-
-
Toepfer, S.1
Zellmer, S.2
Driesch, D.3
Woetzel, D.4
Guthke, R.5
Gebhardt, R.6
Pfaff, M.7
-
241
-
-
84879505221
-
Model-based optimization to explain liver zonation in nitrogen metabolism
-
M. Bartl, M. Pfaff, S. Toepfer, S. Zellmer, R. Gebhardt, S. Schuster, and P. Li Model-based optimization to explain liver zonation in nitrogen metabolism Proceed. 55th International Scientific Colloquium 2010 235 240
-
(2010)
Proceed. 55th International Scientific Colloquium
, pp. 235-240
-
-
Bartl, M.1
Pfaff, M.2
Toepfer, S.3
Zellmer, S.4
Gebhardt, R.5
Schuster, S.6
Li, P.7
-
242
-
-
38049159766
-
Construction of a biological tissue model based on a single-cell model: A computer simulation of metabolic heterogeneity in the liver lobule
-
H. Ohno, Y. Naito, H. Nakajima, and M. Tomita Construction of a biological tissue model based on a single-cell model: a computer simulation of metabolic heterogeneity in the liver lobule Artif. Life 14 2008 3 28
-
(2008)
Artif. Life
, vol.14
, pp. 3-28
-
-
Ohno, H.1
Naito, Y.2
Nakajima, H.3
Tomita, M.4
-
243
-
-
84901262468
-
Integrated metabolic spatial-temporal model for the prediction of ammonia detoxification during liver damage and regeneration
-
F. Schliess, S. Hoehme, S.G. Henkel, A. Ghallab, D. Driesch, J. Böttger, R. Guthke, M. Pfaff, J.G. Hengstler, R. Gebhardt, D. Häussinger, D. Drasdo, and S. Zellmer Integrated metabolic spatial-temporal model for the prediction of ammonia detoxification during liver damage and regeneration Hepatology 60 2014 2040 2051
-
(2014)
Hepatology
, vol.60
, pp. 2040-2051
-
-
Schliess, F.1
Hoehme, S.2
Henkel, S.G.3
Ghallab, A.4
Driesch, D.5
Böttger, J.6
Guthke, R.7
Pfaff, M.8
Hengstler, J.G.9
Gebhardt, R.10
Häussinger, D.11
Drasdo, D.12
Zellmer, S.13
-
244
-
-
0016586921
-
Dynamic control of hepatic glucose metabolism: Studies by experiment and computer simulation
-
R.N. Bergman, and M.E. Refai Dynamic control of hepatic glucose metabolism: studies by experiment and computer simulation Ann. Biomed. Eng. 3 1975 411 432
-
(1975)
Ann. Biomed. Eng.
, vol.3
, pp. 411-432
-
-
Bergman, R.N.1
Refai, M.E.2
-
245
-
-
13844289127
-
Thermodynamic-based computational profiling of cellular regulatory control in hepatocyte metabolism
-
D.A. Beard, and H. Qian Thermodynamic-based computational profiling of cellular regulatory control in hepatocyte metabolism Am. J. Physiol. Endocrinol. Metab. 288 2005 E633 E644
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.288
, pp. E633-E644
-
-
Beard, D.A.1
Qian, H.2
-
246
-
-
33847325401
-
A distributed model of carbohydrate transport and metabolism in the liver during rest and high-intensity exercise
-
E. Chalhoub, L. Xie, V. Balasubramanian, J. Kim, and J. Belovich A distributed model of carbohydrate transport and metabolism in the liver during rest and high-intensity exercise Ann. Biomed. Eng. 35 2007 474 491
-
(2007)
Ann. Biomed. Eng.
, vol.35
, pp. 474-491
-
-
Chalhoub, E.1
Xie, L.2
Balasubramanian, V.3
Kim, J.4
Belovich, J.5
-
247
-
-
77953400851
-
Tissue-level modeling of xenobiotic metabolism in liver: An emerging tool for enabling clinical translational research
-
M.G. Lerapetritou, P.G. Georgopoulos, C.M. Roth, and L.P. Androulakis Tissue-level modeling of xenobiotic metabolism in liver: an emerging tool for enabling clinical translational research Clin. Transl. Sci. 2 2009 228 237
-
(2009)
Clin. Transl. Sci.
, vol.2
, pp. 228-237
-
-
Lerapetritou, M.G.1
Georgopoulos, P.G.2
Roth, C.M.3
Androulakis, L.P.4
-
248
-
-
33751413561
-
Physiologically based synthetic models of hepatic disposition
-
C.A. Hunt, G.E.P. Ropella, L. Yan, D.Y. Hung, and M.S. Roberts Physiologically based synthetic models of hepatic disposition J. Pharmacokinet. Pharmacodyn. 33 2006 737 772
-
(2006)
J. Pharmacokinet. Pharmacodyn.
, vol.33
, pp. 737-772
-
-
Hunt, C.A.1
Ropella, G.E.P.2
Yan, L.3
Hung, D.Y.4
Roberts, M.S.5
-
249
-
-
77954484528
-
Computational experiments reveal plausible mechanisms for changing patterns of hepatic zonation of xenobiotic clearance and hepatotoxicity
-
S. Sheikh-Bahaei, J.J. Maher, and C.A. Hunt Computational experiments reveal plausible mechanisms for changing patterns of hepatic zonation of xenobiotic clearance and hepatotoxicity J. Theor. Biol. 265 2010 718 733
-
(2010)
J. Theor. Biol.
, vol.265
, pp. 718-733
-
-
Sheikh-Bahaei, S.1
Maher, J.J.2
Hunt, C.A.3
-
250
-
-
58149460398
-
Discovering plausible mechanistic details of hepatic drug interactions
-
T.N. Lam, and C.A. Hunt Discovering plausible mechanistic details of hepatic drug interactions Drug Metab. Dispos. 37 2009 237 246
-
(2009)
Drug Metab. Dispos.
, vol.37
, pp. 237-246
-
-
Lam, T.N.1
Hunt, C.A.2
-
251
-
-
42049114288
-
Modeling and simulation of hepatic drug disposition using a physiologically based, multi-agent in silico liver
-
L. Yan, G.E. Ropella, S. Park, M.S. Roberts, and C.A. Hunt Modeling and simulation of hepatic drug disposition using a physiologically based, multi-agent in silico liver Pharm. Res. 25 2008 1023 1036
-
(2008)
Pharm. Res.
, vol.25
, pp. 1023-1036
-
-
Yan, L.1
Ropella, G.E.2
Park, S.3
Roberts, M.S.4
Hunt, C.A.5
-
252
-
-
41549093231
-
Predictions of hepatic disposition properties using a mechanistically realistic, physiologically based model
-
L. Yan, S. Sheihk-Bahaei, S. Park, G.E.P. Ropella, and C.A. Hunt Predictions of hepatic disposition properties using a mechanistically realistic, physiologically based model Drug Metab. Dispos. 36 2008 759 768
-
(2008)
Drug Metab. Dispos.
, vol.36
, pp. 759-768
-
-
Yan, L.1
Sheihk-Bahaei, S.2
Park, S.3
Ropella, G.E.P.4
Hunt, C.A.5
-
254
-
-
77957786145
-
A cell-based simulation software for multi-cellular systems
-
S. Hoehme, and D. Drasdo A cell-based simulation software for multi-cellular systems Bioinformatics 26 2010 2641 2642
-
(2010)
Bioinformatics
, vol.26
, pp. 2641-2642
-
-
Hoehme, S.1
Drasdo, D.2
-
255
-
-
84923638732
-
Modeling liver regeneration in a virtual lobe
-
S. Hoehme, S. Hammad, A. Othman, I. von Recklinghausen, J. Boettger, R. Gebhardt, O. Dirsch, J.G. Hengstler, and D. Drasdo Modeling liver regeneration in a virtual lobe Proc. Living Imaging Workshop 2011
-
(2011)
Proc. Living Imaging Workshop
-
-
Hoehme, S.1
Hammad, S.2
Othman, A.3
Von Recklinghausen, I.4
Boettger, J.5
Gebhardt, R.6
Dirsch, O.7
Hengstler, J.G.8
Drasdo, D.9
-
256
-
-
84923573833
-
A quantitative mathematical modeling approach to liver regeneration
-
D. Häussinger, De Gruyter Berlin/Boston
-
D. Drasdo, S. Hoehme, and J.G. Hengstler A quantitative mathematical modeling approach to liver regeneration D. Häussinger, Liver Regeneration 2011 De Gruyter Berlin/Boston 159 174
-
(2011)
Liver Regeneration
, pp. 159-174
-
-
Drasdo, D.1
Hoehme, S.2
Hengstler, J.G.3
-
257
-
-
70349968103
-
A minimal model for hepatic fatty acid balance during fasting: Application to PPAR alpha-deficient mice
-
P. Blavy, F. Gondret, H. Guillou, S. Lagarrigue, P.G.P. Martin, J. van Milgen, O. Radulescu, and A. Siegel A minimal model for hepatic fatty acid balance during fasting: application to PPAR alpha-deficient mice J. Theor. Biol. 261 2009 266 278
-
(2009)
J. Theor. Biol.
, vol.261
, pp. 266-278
-
-
Blavy, P.1
Gondret, F.2
Guillou, H.3
Lagarrigue, S.4
Martin, P.G.P.5
Van Milgen, J.6
Radulescu, O.7
Siegel, A.8
-
258
-
-
0024465354
-
Application of simulation modeling to lipid peroxidation processes
-
A.L. Tappel, A.A. Tappel, and C.G. Fraga Application of simulation modeling to lipid peroxidation processes Free Radic. Biol. Med. 7 1989 361 368
-
(1989)
Free Radic. Biol. Med.
, vol.7
, pp. 361-368
-
-
Tappel, A.L.1
Tappel, A.A.2
Fraga, C.G.3
-
259
-
-
0033673149
-
A pathway model of lipid metabolism to predict the effect of genetic variability on lipid levels
-
H. Knoblauch, H. Schuster, F.C. Luft, and J. Reich A pathway model of lipid metabolism to predict the effect of genetic variability on lipid levels J. Mol. Med. (Berl.) 78 2000 507 515
-
(2000)
J. Mol. Med. (Berl.)
, vol.78
, pp. 507-515
-
-
Knoblauch, H.1
Schuster, H.2
Luft, F.C.3
Reich, J.4
-
260
-
-
24344447730
-
A mathematical model of fatty acid metabolism and VLDL assembly in human liver
-
P.R. Shorten, and G.C. Upreti A mathematical model of fatty acid metabolism and VLDL assembly in human liver Biochim. Biophys. Acta 1736 2005 94 108
-
(2005)
Biochim. Biophys. Acta
, vol.1736
, pp. 94-108
-
-
Shorten, P.R.1
Upreti, G.C.2
-
261
-
-
34547825554
-
Bioinformatics strategies for lipidomics analysis: Characterization of obesity related hepatic steatosis
-
L. Yetukuri, M. Katajamaa, G. Medina-Gomez, T. Seppänen-Laakso, A. Vidal-Puig, and M. Oresic Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis BMC Syst. Biol. 1 2007 12
-
(2007)
BMC Syst. Biol.
, vol.1
, pp. 12
-
-
Yetukuri, L.1
Katajamaa, M.2
Medina-Gomez, G.3
Seppänen-Laakso, T.4
Vidal-Puig, A.5
Oresic, M.6
-
262
-
-
84859840179
-
The virtual liver: A multidisciplinary, multilevel challenge for systems biology
-
H.-G. Holzhütter, D. Drasdo, T. Preusser, J. Lippert, and A.M. Henney The virtual liver: a multidisciplinary, multilevel challenge for systems biology Wiley Interdiscip. Rev. Syst. Biol. Med. 4 2012 221 235
-
(2012)
Wiley Interdiscip. Rev. Syst. Biol. Med.
, vol.4
, pp. 221-235
-
-
Holzhütter, H.-G.1
Drasdo, D.2
Preusser, T.3
Lippert, J.4
Henney, A.M.5
|