Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

Nature

Volumn 485, Issue 7396, 2012, Pages 62-68

  Solt, Laura A ^a   Wang, Yongjun ^a   Banerjee, Subhashis ^a   Hughes, Travis ^a   Kojetin, Douglas J ^a   Lundasen, Thomas ^a   Shin, Youseung ^a   Liu, Jin ^a   Cameron, Michael D ^a   Noel, Romain ^b   Yoo, Seung Hee ^b   Takahashi, Joseph S ^b   Butler, Andrew A ^a   Kamenecka, Theodore M ^a   Burris, Thomas P ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOBESITY AGENT; NUCLEAR RECEPTOR REV ERB AGONIST; SR 9009; SR 9011; UNCLASSIFIED DRUG;

CARDIOVASCULAR DISEASE; CIRCADIAN RHYTHM; GENE EXPRESSION; LIGAND; METABOLISM; MUSCLE; PROTEIN; RODENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; DIET THERAPY; DRUG MECHANISM; DRUG METABOLISM; EMBRYO; ENERGY EXPENDITURE; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; METABOLIC DISORDER; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SLEEP DISORDER;

ADIPOSE TISSUE; ANIMALS; BIOLOGICAL CLOCKS; CIRCADIAN RHYTHM; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; HEK293 CELLS; HUMANS; HYPOTHALAMUS; LIVER; METABOLOME; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MUSCLE, SKELETAL; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP D, MEMBER 1; OBESITY; PYRROLIDINES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPRESSOR PROTEINS; THIOPHENES;

MUS;

EID: 84860291442     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11030     Document Type: Article

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