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Volumn 288, Issue 3 51-3, 2005, Pages

Thermodynamic-based computational profiling of cellular regulatory control in hepatocyte metabolism

Author keywords

Biochemical network; Network thermodynamics; Nonequilibrium steady state

Indexed keywords

ARTICLE; CALCULATION; CELL METABOLISM; CONCENTRATION RESPONSE; CONTROL SYSTEM; DRUG TARGETING; ENZYME ACTIVITY; GLUCONEOGENESIS; GLYCOGEN METABOLISM; GLYCOGEN STORAGE DISEASE TYPE 1; GLYCOGEN STORAGE DISEASE TYPE 6; GLYCOGEN SYNTHESIS; GLYCOGENOLYSIS; LIVER CELL; LIVER METABOLISM; MATHEMATICAL MODEL; METABOLIC REGULATION; PHYSICAL CHEMISTRY; PREDICTION; PRIORITY JOURNAL; REGULATORY MECHANISM; TECHNIQUE; THERMODYNAMICS;

EID: 13844289127     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00239.2004     Document Type: Article
Times cited : (62)

References (34)
  • 1
    • 0026335985 scopus 로고
    • Equilibrium compositions of solutions of biochemical species and heats of biochemical reactions
    • Alberty RA. Equilibrium compositions of solutions of biochemical species and heats of biochemical reactions. Proc Natl Acad Sci USA 88: 3268-3271, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3268-3271
    • Alberty, R.A.1
  • 2
    • 0001505494 scopus 로고
    • Degrees of freedom in biochemical reaction systems at specific pH and pMg
    • Alberty RA. Degrees of freedom in biochemical reaction systems at specific pH and pMg. J Phys Chem 96: 9614-9621, 1992.
    • (1992) J Phys Chem , vol.96 , pp. 9614-9621
    • Alberty, R.A.1
  • 3
    • 0027163355 scopus 로고
    • Levels of thermodynamic treatment of biochemical reaction systems
    • Alberty RA. Levels of thermodynamic treatment of biochemical reaction systems. Biophys J 65: 1243-1254, 1993.
    • (1993) Biophys J , vol.65 , pp. 1243-1254
    • Alberty, R.A.1
  • 4
    • 0037438571 scopus 로고    scopus 로고
    • The role of water in the thermodynamics of dilute aqueous solutions
    • Alberty RA. The role of water in the thermodynamics of dilute aqueous solutions. Biophys Chem 100: 183-192, 2003.
    • (2003) Biophys Chem , vol.100 , pp. 183-192
    • Alberty, R.A.1
  • 6
    • 0026457728 scopus 로고
    • Standard thermodynamic formation properties for the adenosine 5′-triphosphate series
    • Alberty RA and Goldberg RN. Standard thermodynamic formation properties for the adenosine 5′-triphosphate series. Biochemistry 31: 10610-10615, 1992.
    • (1992) Biochemistry , vol.31 , pp. 10610-10615
    • Alberty, R.A.1    Goldberg, R.N.2
  • 7
    • 0001462384 scopus 로고
    • Modeling in the analysis of solute and water exchange in the microvasculature
    • Bethesda, MD: Am. Physiol. Soc., sect. 2, chapt. 13
    • Bassingthwaighte JB and Goresky CA. Modeling in the analysis of solute and water exchange in the microvasculature. In: Handbook of Physiology. The Cardiovascular System. Microcirculation. Bethesda, MD: Am. Physiol. Soc., 1984, sect. 2, vol. IV, pt. 1, chapt. 13, p. 549-626.
    • (1984) Handbook of Physiology. The Cardiovascular System. Microcirculation , vol.4 , Issue.1 PART , pp. 549-626
    • Bassingthwaighte, J.B.1    Goresky, C.A.2
  • 8
    • 2342627280 scopus 로고    scopus 로고
    • Thermodynamic constraints for biochemical networks
    • Beard DA, Babson E, Curtis E, and Qian H. Thermodynamic constraints for biochemical networks. J Theor Biol 228: 327-333, 2004.
    • (2004) J Theor Biol , vol.228 , pp. 327-333
    • Beard, D.A.1    Babson, E.2    Curtis, E.3    Qian, H.4
  • 9
    • 0036286631 scopus 로고    scopus 로고
    • Energy balance for analysis of complex metabolic networks
    • Beard DA, Liang SD, and Qian H. Energy balance for analysis of complex metabolic networks. Biophys J 83: 79-86, 2002.
    • (2002) Biophys J , vol.83 , pp. 79-86
    • Beard, D.A.1    Liang, S.D.2    Qian, H.3
  • 10
    • 13844280250 scopus 로고    scopus 로고
    • Stoichiometric foundation of large-scale biochemical system analysis
    • edited by Ciabanu G and Rozenberg G. Berlin: Springer
    • Beard DA, Qian H, and Bassingthwaighte JB. Stoichiometric foundation of large-scale biochemical system analysis. In: Modelling in Molecular Biology, edited by Ciabanu G and Rozenberg G. Berlin: Springer, 2004, p. 1-19.
    • (2004) Modelling in Molecular Biology , pp. 1-19
    • Beard, D.A.1    Qian, H.2    Bassingthwaighte, J.B.3
  • 11
    • 0142139334 scopus 로고    scopus 로고
    • Myocardial oxygenation in isolated hearts predicted by an anatomically realistic microvascular transport model
    • Beard DA, Schenkman KA, and Feigl EO. Myocardial oxygenation in isolated hearts predicted by an anatomically realistic microvascular transport model. Am J Physiol Heart Circ Physiol 285: H1826-H1836, 2003.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Beard, D.A.1    Schenkman, K.A.2    Feigl, E.O.3
  • 12
    • 0037088286 scopus 로고    scopus 로고
    • Ethanol perfusion increases the yield of oxidative phosphorylation in isolated liver of fed rats
    • Beauvieux MC, Tissier P, Couzigou P, Gin H, Canioni P, and Gallis JL. Ethanol perfusion increases the yield of oxidative phosphorylation in isolated liver of fed rats. Biochim Biophys Acta 1570: 135-140, 2002.
    • (2002) Biochim Biophys Acta , vol.1570 , pp. 135-140
    • Beauvieux, M.C.1    Tissier, P.2    Couzigou, P.3    Gin, H.4    Canioni, P.5    Gallis, J.L.6
  • 13
    • 0035922073 scopus 로고    scopus 로고
    • Metabolic-flux analysis of continuously cultured hybridoma cells using (13)CO(2) mass spectrometry in combination with (13)C-lactate nuclear magnetic resonance spectroscopy and metabolite balancing
    • Bonarius HP, Ozemre A, Timmerarends B, Skrabal P, Tramper J, Schmid G, and Heinzle E. Metabolic-flux analysis of continuously cultured hybridoma cells using (13)CO(2) mass spectrometry in combination with (13)C-lactate nuclear magnetic resonance spectroscopy and metabolite balancing. Biotechnol Bioeng 74: 528-538, 2001.
    • (2001) Biotechnol Bioeng , vol.74 , pp. 528-538
    • Bonarius, H.P.1    Ozemre, A.2    Timmerarends, B.3    Skrabal, P.4    Tramper, J.5    Schmid, G.6    Heinzle, E.7
  • 14
    • 0037142769 scopus 로고    scopus 로고
    • Metabolic pathway analysis of a recombinant yeast for rational strain development
    • Carlson R, Fell D, and Srienc F. Metabolic pathway analysis of a recombinant yeast for rational strain development. Biotechnol Bioeng 79: 121-134, 2002.
    • (2002) Biotechnol Bioeng , vol.79 , pp. 121-134
    • Carlson, R.1    Fell, D.2    Srienc, F.3
  • 16
    • 0034920362 scopus 로고    scopus 로고
    • Glucagon attenuates the action of insulin on glucose output in the liver of the Goto-Kakizaki rat perfused in situ
    • Doi Y, Iwai M, Matsuura B, and Onji M. Glucagon attenuates the action of insulin on glucose output in the liver of the Goto-Kakizaki rat perfused in situ. Pflügers Arch 442: 537-541, 2001.
    • (2001) Pflügers Arch , vol.442 , pp. 537-541
    • Doi, Y.1    Iwai, M.2    Matsuura, B.3    Onji, M.4
  • 17
    • 0035125986 scopus 로고    scopus 로고
    • In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data
    • Edwards JS, Ibarra RU, and Palsson BO. In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data. Nat Biotechnol 19: 125-130, 2001.
    • (2001) Nat Biotechnol , vol.19 , pp. 125-130
    • Edwards, J.S.1    Ibarra, R.U.2    Palsson, B.O.3
  • 18
    • 0034625143 scopus 로고    scopus 로고
    • The Escherichia coli MG1655 in silico metabolic genotype: Its definition, characteristics, and capabilities
    • Edwards JS and Palsson BO. The Escherichia coli MG1655 in silico metabolic genotype: its definition, characteristics, and capabilities. Proc Natl Acad Sci USA 97: 5528-5533, 2000.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5528-5533
    • Edwards, J.S.1    Palsson, B.O.2
  • 19
    • 0034519221 scopus 로고    scopus 로고
    • Robustness analysis of the Escherichia coli metabolic network
    • Edwards JS and Palsson BO. Robustness analysis of the Escherichia coli metabolic network. Biotechnol Prog 16: 927-939, 2000.
    • (2000) Biotechnol Prog , vol.16 , pp. 927-939
    • Edwards, J.S.1    Palsson, B.O.2
  • 20
    • 0034329627 scopus 로고    scopus 로고
    • Shared control of hepatic glycogen synthesis by glycogen synthase and glucokinase
    • Gomis RR, Ferrer JC, and Guinovart JJ. Shared control of hepatic glycogen synthesis by glycogen synthase and glucokinase. Biochem J 351: 811-816, 2000.
    • (2000) Biochem J , vol.351 , pp. 811-816
    • Gomis, R.R.1    Ferrer, J.C.2    Guinovart, J.J.3
  • 21
    • 0016198219 scopus 로고
    • The concentration and control of cytoplasmic free inorganic pyrophosphate in rat liver in vivo
    • Guynn RW, Veloso D, Lawson JW, and Veech RL. The concentration and control of cytoplasmic free inorganic pyrophosphate in rat liver in vivo. Biochem J 140: 369-375, 1974.
    • (1974) Biochem J , vol.140 , pp. 369-375
    • Guynn, R.W.1    Veloso, D.2    Lawson, J.W.3    Veech, R.L.4
  • 23
    • 0035283048 scopus 로고    scopus 로고
    • Theoretical studies on the regulation of oxidative phosphorylation in intact tissues
    • Korzeniewski B. Theoretical studies on the regulation of oxidative phosphorylation in intact tissues. Biochim Biophys Acta 1504: 31-45, 2001.
    • (2001) Biochim Biophys Acta , vol.1504 , pp. 31-45
    • Korzeniewski, B.1
  • 25
    • 0033568267 scopus 로고    scopus 로고
    • Model of 2,3-bisphosphoglycerate metabolism in the human erythrocyte based on detailed enzyme kinetic equations: In vivo kinetic characterization of 2,3-bisphosphoglycerate synthase/phosphatase using 13C and 31P NMR
    • Mulquiney PJ, Bubb WA, and Kuchel PW. Model of 2,3-bisphosphoglycerate metabolism in the human erythrocyte based on detailed enzyme kinetic equations: in vivo kinetic characterization of 2,3-bisphosphoglycerate synthase/phosphatase using 13C and 31P NMR. Biochem J 342: 567-580, 1999.
    • (1999) Biochem J , vol.342 , pp. 567-580
    • Mulquiney, P.J.1    Bubb, W.A.2    Kuchel, P.W.3
  • 26
    • 0033567930 scopus 로고    scopus 로고
    • Model of 2,3-bisphosphoglycerate metabolism in the human erythrocyte based on detailed enzyme kinetic equations: Computer simulation and metabolic control analysis
    • Mulquiney PJ and Kuchel PW. Model of 2,3-bisphosphoglycerate metabolism in the human erythrocyte based on detailed enzyme kinetic equations: computer simulation and metabolic control analysis. Biochem J 342: 597-604, 1999.
    • (1999) Biochem J , vol.342 , pp. 597-604
    • Mulquiney, P.J.1    Kuchel, P.W.2
  • 27
    • 0033568448 scopus 로고    scopus 로고
    • Model of 2,3-bisphosphoglycerate metabolism in the human erythrocyte based on detailed enzyme kinetic equations: Equations and parameter refinement
    • Mulquiney PJ and Kuchel PW. Model of 2,3-bisphosphoglycerate metabolism in the human erythrocyte based on detailed enzyme kinetic equations: equations and parameter refinement. Biochem J 342: 581-596, 1999.
    • (1999) Biochem J , vol.342 , pp. 581-596
    • Mulquiney, P.J.1    Kuchel, P.W.2
  • 28
    • 0037315604 scopus 로고    scopus 로고
    • Stoichiometric network theory for nonequilibrium biochemical systems
    • Qian H, Beard DA, and Liang SD. Stoichiometric network theory for nonequilibrium biochemical systems. Eur J Biochem 270: 415-421, 2003.
    • (2003) Eur J Biochem , vol.270 , pp. 415-421
    • Qian, H.1    Beard, D.A.2    Liang, S.D.3
  • 29
    • 0033136109 scopus 로고    scopus 로고
    • Metabolic pathway analysis: Basic concepts and scientific applications in the post-genomic era
    • Schilling CH, Schuster S, Palsson BO, and Heinrich R. Metabolic pathway analysis: basic concepts and scientific applications in the post-genomic era. Biotechnol Prog 15: 296-303, 1999.
    • (1999) Biotechnol Prog , vol.15 , pp. 296-303
    • Ch, S.1    Schuster, S.2    Palsson, B.O.3    Heinrich, R.4
  • 30
  • 31
    • 0032475899 scopus 로고    scopus 로고
    • Impaired glucose sensing by intrahepatic, muscarinic nerves for an insulin-stimulated hepatic glucose uptake in streptozotocin-diabetic rats
    • Stumpel F, Scholtka B, and Jungermann K. Impaired glucose sensing by intrahepatic, muscarinic nerves for an insulin-stimulated hepatic glucose uptake in streptozotocin-diabetic rats. FEBS Lett 436: 185-188, 1998.
    • (1998) FEBS Lett , vol.436 , pp. 185-188
    • Stumpel, F.1    Scholtka, B.2    Jungermann, K.3
  • 32
    • 0028146781 scopus 로고
    • Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110
    • Varma A and Palsson BO. Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110. Appl Environ Microbiol 60: 3724-3731, 1994.
    • (1994) Appl Environ Microbiol , vol.60 , pp. 3724-3731
    • Varma, A.1    Palsson, B.O.2
  • 33
    • 0034086313 scopus 로고    scopus 로고
    • Regulation of mitochondrial respiration in heart cells analyzed by reaction-diffusion model of energy transfer
    • Vendelin M, Kongas O, and Saks V. Regulation of mitochondrial respiration in heart cells analyzed by reaction-diffusion model of energy transfer. Am J Physiol Cell Physiol 278: C747-C764, 2000.
    • (2000) Am J Physiol Cell Physiol , vol.278
    • Vendelin, M.1    Kongas, O.2    Saks, V.3


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