메뉴 건너뛰기




Volumn 147, Issue 3, 2006, Pages 1480-1487

Liver triglyceride secretion and lipid oxidative metabolism are rapidly altered by leptin in vivo

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; LEPTIN; PHOSPHATIDYLINOSITOL 3 KINASE; STAT PROTEIN; TRIACYLGLYCEROL; TYLOXAPOL;

EID: 32644436318     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2005-0731     Document Type: Article
Times cited : (101)

References (40)
  • 1
    • 6344221594 scopus 로고    scopus 로고
    • Congenital leptin deficiency due to homozygosity for the Δ133G mutation: Report of another case and evaluation of response to four years of leptin therapy
    • Gibson WT, Farooqi IS, Moreau M, DePaoli AM, Lawrence E, O'Rahilly S, Trussell RA 2004 Congenital leptin deficiency due to homozygosity for the Δ133G mutation: report of another case and evaluation of response to four years of leptin therapy. J Clin Endocrinol Metab 89:4821-4826
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 4821-4826
    • Gibson, W.T.1    Farooqi, I.S.2    Moreau, M.3    DePaoli, A.M.4    Lawrence, E.5    O'Rahilly, S.6    Trussell, R.A.7
  • 4
    • 0033517284 scopus 로고    scopus 로고
    • Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy
    • Shimomura I, Hammer RE, Ikemoto S, Brown MS, Goldstein JL 1999 Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy. Nature 401:73-76
    • (1999) Nature , vol.401 , pp. 73-76
    • Shimomura, I.1    Hammer, R.E.2    Ikemoto, S.3    Brown, M.S.4    Goldstein, J.L.5
  • 6
    • 0043172530 scopus 로고    scopus 로고
    • Effect of leptin replacement on intrahepatic and intramyocellular lipid content in patients with generalized lipodystrophy
    • Simha V, Szczepaniak LS, Wagner AJ, DePaoli AM, Garg A 2003 Effect of leptin replacement on intrahepatic and intramyocellular lipid content in patients with generalized lipodystrophy. Diabetes Care 26:30-35
    • (2003) Diabetes Care , vol.26 , pp. 30-35
    • Simha, V.1    Szczepaniak, L.S.2    Wagner, A.J.3    DePaoli, A.M.4    Garg, A.5
  • 7
    • 2542444292 scopus 로고    scopus 로고
    • Impaired activation of phosphatidylinositol 3-kinase by leptin is a novel mechanism of hepatic leptin resistance in diet-induced obesity
    • Huang W, Dedousis N, Bhatt BA, O'Doherty RM 2004 Impaired activation of phosphatidylinositol 3-kinase by leptin is a novel mechanism of hepatic leptin resistance in diet-induced obesity. J Biol Chem 279:21695-21700
    • (2004) J Biol Chem , vol.279 , pp. 21695-21700
    • Huang, W.1    Dedousis, N.2    Bhatt, B.A.3    O'Doherty, R.M.4
  • 9
    • 0034061685 scopus 로고    scopus 로고
    • Correction of diet-induced hyperglycemia, hyperinsulinemia, and skeletal muscle insulin resistance by moderate hyperleptinemia
    • Buettner R, Newgard CB, Rhodes CJ, O'Doherty RM 2000 Correction of diet-induced hyperglycemia, hyperinsulinemia, and skeletal muscle insulin resistance by moderate hyperleptinemia. Am J Physiol 278:E563-E569
    • (2000) Am J Physiol , vol.278
    • Buettner, R.1    Newgard, C.B.2    Rhodes, C.J.3    O'Doherty, R.M.4
  • 11
    • 0036298225 scopus 로고    scopus 로고
    • Leptin increases FA oxidation in lean but not obese human skeletal muscle: Evidence of peripheral leptin resistance
    • Steinberg GR, Parolin ML, Heigenhauser GJ, Dyck DJ 2002 Leptin increases FA oxidation in lean but not obese human skeletal muscle: evidence of peripheral leptin resistance. Am J Physiol 283:E187-E192
    • (2002) Am J Physiol , vol.283
    • Steinberg, G.R.1    Parolin, M.L.2    Heigenhauser, G.J.3    Dyck, D.J.4
  • 12
    • 0036087336 scopus 로고    scopus 로고
    • Fatty acid oxidation and triacylglycerol hydrolysis are enhanced after chronic leptin treatment in rats
    • Steinberg GR, Bonen A, Dyck DJ 2002 Fatty acid oxidation and triacylglycerol hydrolysis are enhanced after chronic leptin treatment in rats. Am J Physiol 282:E593-E600
    • (2002) Am J Physiol , vol.282
    • Steinberg, G.R.1    Bonen, A.2    Dyck, D.J.3
  • 14
    • 0033005654 scopus 로고    scopus 로고
    • Leptin opposes insulin's effects on fatty acid partitioning in muscles isolated from obese ob/ob mice
    • Muoio DM, Dohm GL, Tapscott EB, Coleman RA 1999 Leptin opposes insulin's effects on fatty acid partitioning in muscles isolated from obese ob/ob mice. Am J Physiol 276:E913-E921
    • (1999) Am J Physiol , vol.276
    • Muoio, D.M.1    Dohm, G.L.2    Tapscott, E.B.3    Coleman, R.A.4
  • 17
    • 0037119410 scopus 로고    scopus 로고
    • Leptin activates cardiac fatty acid oxidation independent of changes in the AMP-activated protein kinase-acetyl-CoA carboxylase-malonyl-CoA axis
    • Atkinson LL, Fischer MA, Lopaschuk GD 2002 Leptin activates cardiac fatty acid oxidation independent of changes in the AMP-activated protein kinase-acetyl-CoA carboxylase-malonyl-CoA axis. J Biol Chem 277:29424-29430
    • (2002) J Biol Chem , vol.277 , pp. 29424-29430
    • Atkinson, L.L.1    Fischer, M.A.2    Lopaschuk, G.D.3
  • 18
    • 0033514956 scopus 로고    scopus 로고
    • Regulation of fatty acid homeostasis in cells: Novel role of leptin
    • USA
    • Unger RH, Zhou YT, Orci L 1999 Regulation of fatty acid homeostasis in cells: novel role of leptin. Proc Natl Acad Sci USA 96:2327-2332
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 2327-2332
    • Unger, R.H.1    Zhou, Y.T.2    Orci, L.3
  • 21
    • 3042846012 scopus 로고    scopus 로고
    • In vivo regulation of SREBP-1c in skeletal muscle: Effects of nutritional status, glucose, insulin, and leptin
    • Commerford SR, Peng L, Dube JJ, O'Doherty RM 2004 In vivo regulation of SREBP-1c in skeletal muscle: effects of nutritional status, glucose, insulin, and leptin. Am J Physiol 287:R218-R227
    • (2004) Am J Physiol , vol.287
    • Commerford, S.R.1    Peng, L.2    Dube, J.J.3    O'Doherty, R.M.4
  • 23
    • 0021867618 scopus 로고
    • Bregma, λ and the interaural midpoint in stereotaxic surgery with rats of different sex, strain and weight
    • Paxinos G, Watson C, Pennisi M, Topple A 1985 Bregma, λ and the interaural midpoint in stereotaxic surgery with rats of different sex, strain and weight. J Neurosci Methods 13:139-143
    • (1985) J Neurosci Methods , vol.13 , pp. 139-143
    • Paxinos, G.1    Watson, C.2    Pennisi, M.3    Topple, A.4
  • 24
    • 2342584091 scopus 로고    scopus 로고
    • Intracerebroventricular leptin regulates hepatic cholesterol metabolism
    • Vanpatten S, Karkanias GB, Rossetti L, Cohen DE 2004 Intracerebroventricular leptin regulates hepatic cholesterol metabolism. Biochem J 379:229-233
    • (2004) Biochem J , vol.379 , pp. 229-233
    • Vanpatten, S.1    Karkanias, G.B.2    Rossetti, L.3    Cohen, D.E.4
  • 25
    • 0021378892 scopus 로고
    • Hyperinsulinemia and in vivo very-low-density lipoprotein-triglyceride kinetics
    • Steiner G, Haynes FJ, Yoshino G, Vranic M 1984 Hyperinsulinemia and in vivo very-low-density lipoprotein-triglyceride kinetics. Am J Physiol 246:E187-E192
    • (1984) Am J Physiol , vol.246
    • Steiner, G.1    Haynes, F.J.2    Yoshino, G.3    Vranic, M.4
  • 26
    • 3042551249 scopus 로고    scopus 로고
    • Increased β-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation
    • Perdomo G, Commerford SR, Richard AM, Adams SH, Corkey BE, O'Doherty RM, Brown NF 2004 Increased β-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation. J Biol Chem 279:27177-27186
    • (2004) J Biol Chem , vol.279 , pp. 27177-27186
    • Perdomo, G.1    Commerford, S.R.2    Richard, A.M.3    Adams, S.H.4    Corkey, B.E.5    O'Doherty, R.M.6    Brown, N.F.7
  • 27
    • 0020025981 scopus 로고
    • Rapid method for determining cholesteryl ester transitions of apoB-containing lipoproteins
    • Waugh DA, Small DM 1982 Rapid method for determining cholesteryl ester transitions of apoB-containing lipoproteins. J Lipid Res 23:201-204
    • (1982) J Lipid Res , vol.23 , pp. 201-204
    • Waugh, D.A.1    Small, D.M.2
  • 28
    • 0029093341 scopus 로고
    • High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl-CoA levels due to an increase in 5′-AMP-activated protein kinase inhibition of acetyl-CoA carboxylase
    • Kudo N, Barr AJ, Barr RL, Desai S, Lopaschuk GD 1995 High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl-CoA levels due to an increase in 5′-AMP-activated protein kinase inhibition of acetyl-CoA carboxylase. J Biol Chem 270:17513-17520
    • (1995) J Biol Chem , vol.270 , pp. 17513-17520
    • Kudo, N.1    Barr, A.J.2    Barr, R.L.3    Desai, S.4    Lopaschuk, G.D.5
  • 31
    • 0034457883 scopus 로고    scopus 로고
    • In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: Overlapping but distinct pathways from insulin
    • Kim YB, Uotani S, Pierroz DD, Flier JS, Kahn BB 2000 In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin. Endocrinology 141:2328-2339
    • (2000) Endocrinology , vol.141 , pp. 2328-2339
    • Kim, Y.B.1    Uotani, S.2    Pierroz, D.D.3    Flier, J.S.4    Kahn, B.B.5
  • 34
    • 0033638542 scopus 로고    scopus 로고
    • Development of leptin resistance in rat soleus muscle in response to high-fat diets
    • Steinberg GR, Dyck DJ 2000 Development of leptin resistance in rat soleus muscle in response to high-fat diets. Am J Physiol 279:E1374-E1382
    • (2000) Am J Physiol , vol.279
    • Steinberg, G.R.1    Dyck, D.J.2
  • 35
    • 0141925771 scopus 로고    scopus 로고
    • Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart
    • Kovacic S, Soltys CL, Barr AJ, Shiojima I, Walsh K, Dyck JR 2003 Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart. J Biol Chem 278:39422-39427
    • (2003) J Biol Chem , vol.278 , pp. 39422-39427
    • Kovacic, S.1    Soltys, C.L.2    Barr, A.J.3    Shiojima, I.4    Walsh, K.5    Dyck, J.R.6
  • 36
    • 0037072876 scopus 로고    scopus 로고
    • Leptin promotes biliary cholesterol elimination during weight loss in ob/ob mice by regulating the enterohepatic circulation of bile salts
    • Hyogo H, Roy S, Paigen B, Cohen DE 2002 Leptin promotes biliary cholesterol elimination during weight loss in ob/ob mice by regulating the enterohepatic circulation of bile salts. J Biol Chem 277:34117-34124
    • (2002) J Biol Chem , vol.277 , pp. 34117-34124
    • Hyogo, H.1    Roy, S.2    Paigen, B.3    Cohen, D.E.4
  • 37
    • 0034891367 scopus 로고    scopus 로고
    • Impaired biliary lipid secretion in obese Zucker rats: Leptin promotes hepatic cholesterol clearance
    • VanPatten S, Ranginani N, Shefer S, Nguyen LB, Rossetti L, Cohen DE 2001 Impaired biliary lipid secretion in obese Zucker rats: leptin promotes hepatic cholesterol clearance. Am J Physiol 281:G393-G404
    • (2001) Am J Physiol , vol.281
    • Vanpatten, S.1    Ranginani, N.2    Shefer, S.3    Nguyen, L.B.4    Rossetti, L.5    Cohen, D.E.6
  • 38
    • 0033548092 scopus 로고    scopus 로고
    • Increased high density lipoprotein (HDL), defective hepatic catabolism of ApoA-I and ApoA-II, and decreased ApoA-I mRNA in ob/ob mice. Possible role of leptin in stimulation of HDL turnover
    • Silver DL, Jiang XC, Tall AR 1999 Increased high density lipoprotein (HDL), defective hepatic catabolism of ApoA-I and ApoA-II, and decreased ApoA-I mRNA in ob/ob mice. Possible role of leptin in stimulation of HDL turnover. J Biol Chem 274:4140-4146
    • (1999) J Biol Chem , vol.274 , pp. 4140-4146
    • Silver, D.L.1    Jiang, X.C.2    Tall, A.R.3
  • 40
    • 0032852070 scopus 로고    scopus 로고
    • Leptin has acute effects on glucose and lipid metabolism in both lean and gold thioglucose-obese mice
    • Bryson JM, Phuyal JL, Swan V, Caterson ID 1999 Leptin has acute effects on glucose and lipid metabolism in both lean and gold thioglucose-obese mice. Am J Physiol 277:E417-E422
    • (1999) Am J Physiol , vol.277
    • Bryson, J.M.1    Phuyal, J.L.2    Swan, V.3    Caterson, I.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.