Modeling Wnt/β-catenin target gene expression in APC and Wnt gradients under wild type and mutant conditions

Frontiers in Physiology

Volumn 4 FEB, Issue , 2013, Pages

  Benary, Uwe ^a   Kofahl, Bente ^a   Hecht, Andreas ^b   Wolf, Jana ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Feedback; Gene expression; Gradients; Liver; Mathematical modeling; Mutation; Wnt catenin signaling; zonation

Indexed keywords

APC PROTEIN; BETA CATENIN; MESSENGER RNA; T CELL FACTOR PROTEIN; WNT PROTEIN;

GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; GENE MUTATION; GENE REPRESSION; MATHEMATICAL MODEL; NONHUMAN; POSITIVE FEEDBACK; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

EID: 84883781170     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2013.00021     Document Type: Review

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