메뉴 건너뛰기




Volumn 97, Issue C, 2010, Pages 127-150

Molecular determinants of liver zonation

Author keywords

Adenomatous polyposis coli; Liver metabolism; Liver zonation; Transcription; Wnt; Catenin

Indexed keywords


EID: 78649262812     PISSN: 18771173     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-385233-5.00005-2     Document Type: Chapter
Times cited : (78)

References (92)
  • 1
    • 0017754365 scopus 로고
    • Heterogeneous reciprocal localization of fructose-1, 6-bisphosphatase and of glucokinase in microdissected periportal and perivenous rat liver tissue
    • N. Katz, H.F. Teutsch, K. Jungermann, and D. Sasse Heterogeneous reciprocal localization of fructose-1, 6-bisphosphatase and of glucokinase in microdissected periportal and perivenous rat liver tissue FEBS Lett 83 1977 272 276
    • (1977) FEBS Lett , vol.83 , pp. 272-276
    • Katz, N.1    Teutsch, H.F.2    Jungermann, K.3    Sasse, D.4
  • 2
    • 0029800090 scopus 로고    scopus 로고
    • Zonation of parenchymal and nonparenchymal metabolism in liver
    • K. Jungermann, and T. Kietzmann Zonation of parenchymal and nonparenchymal metabolism in liver Annu Rev Nutr 16 1996 179 203
    • (1996) Annu Rev Nutr , vol.16 , pp. 179-203
    • Jungermann, K.1    Kietzmann, T.2
  • 3
    • 0023000206 scopus 로고
    • Cellular analysis by in situ hybridization and immunoperoxidase of alpha-fetoprotein and albumin gene expression in rat liver during the perinatal period
    • A.M. Poliard, D. Bernuau, I. Tournier, L.G. Legres, D. Schoevaert, and G. Feldmann Cellular analysis by in situ hybridization and immunoperoxidase of alpha-fetoprotein and albumin gene expression in rat liver during the perinatal period J Cell Biol 103 1986 777 786
    • (1986) J Cell Biol , vol.103 , pp. 777-786
    • Poliard, A.M.1    Bernuau, D.2    Tournier, I.3    Legres, L.G.4    Schoevaert, D.5    Feldmann, G.6
  • 4
    • 33750536032 scopus 로고    scopus 로고
    • Differential gene expression in periportal and perivenous mouse hepatocytes
    • A. Braeuning, C. Ittrich, C. Kohle, S. Hailfinger, M. Bonin, and A. Buchmann Differential gene expression in periportal and perivenous mouse hepatocytes FEBS J 273 2006 5051 5061
    • (2006) FEBS J , vol.273 , pp. 5051-5061
    • Braeuning, A.1    Ittrich, C.2    Kohle, C.3    Hailfinger, S.4    Bonin, M.5    Buchmann, A.6
  • 5
    • 0029017486 scopus 로고
    • Different hepatocytes express the cholesterol 7 alpha-hydroxylase gene during its circadian modulation in vivo
    • C.M. Berkowitz, C.S. Shen, B.M. Bilir, E. Guibert, and J.J. Gumucio Different hepatocytes express the cholesterol 7 alpha-hydroxylase gene during its circadian modulation in vivo Hepatology 21 1995 1658 1667
    • (1995) Hepatology , vol.21 , pp. 1658-1667
    • Berkowitz, C.M.1    Shen, C.S.2    Bilir, B.M.3    Guibert, E.4    Gumucio, J.J.5
  • 6
    • 33947139689 scopus 로고    scopus 로고
    • Hepatocellular expression of glutamine synthetase: An indicator of morphogen actions as master regulators of zonation in adult liver
    • R. Gebhardt, A. Baldysiak-Figiel, V. Krugel, E. Ueberham, and F. Gaunitz Hepatocellular expression of glutamine synthetase: an indicator of morphogen actions as master regulators of zonation in adult liver Prog Histochem Cytochem 41 2007 201 266
    • (2007) Prog Histochem Cytochem , vol.41 , pp. 201-266
    • Gebhardt, R.1    Baldysiak-Figiel, A.2    Krugel, V.3    Ueberham, E.4    Gaunitz, F.5
  • 7
    • 0026320434 scopus 로고
    • Hepatocellular heterogeneity in ammonia metabolism: Demonstration of limited colocalization of carbamoylphosphate synthetase and glutamine synthetase
    • R. Gebhardt, K. Lindros, W.H. Lamers, and A.F. Moorman Hepatocellular heterogeneity in ammonia metabolism: demonstration of limited colocalization of carbamoylphosphate synthetase and glutamine synthetase Eur J Cell Biol 56 1991 464 467
    • (1991) Eur J Cell Biol , vol.56 , pp. 464-467
    • Gebhardt, R.1    Lindros, K.2    Lamers, W.H.3    Moorman, A.F.4
  • 8
    • 0027055347 scopus 로고
    • Hepatocyte heterogeneity in the metabolism of amino acids and ammonia
    • D. Haussinger, W.H. Lamers, and A.F. Moorman Hepatocyte heterogeneity in the metabolism of amino acids and ammonia Enzyme 46 1992 72 93
    • (1992) Enzyme , vol.46 , pp. 72-93
    • Haussinger, D.1    Lamers, W.H.2    Moorman, A.F.3
  • 9
    • 0031972732 scopus 로고    scopus 로고
    • Zonation of hepatic cytochrome P-450 expression and regulation
    • T. Oinonen, and K.O. Lindros Zonation of hepatic cytochrome P-450 expression and regulation Biochem J 329 Pt 1 1998 17 35
    • (1998) Biochem J , vol.329 , Issue.PART 1 , pp. 17-35
    • Oinonen, T.1    Lindros, K.O.2
  • 10
    • 0030729193 scopus 로고    scopus 로고
    • Developmental appearance of ammonia-metabolizing enzymes in prenatal murine liver
    • R.G. Notenboom, A.F. Moorman, and W.H. Lamers Developmental appearance of ammonia-metabolizing enzymes in prenatal murine liver Microsc Res Tech 39 1997 413 423
    • (1997) Microsc Res Tech , vol.39 , pp. 413-423
    • Notenboom, R.G.1    Moorman, A.F.2    Lamers, W.H.3
  • 12
    • 0028285183 scopus 로고
    • Cell lineage study in the liver using retroviral mediated gene transfer. Evidence against the streaming of hepatocytes in normal liver
    • M.P. Bralet, S. Branchereau, C. Brechot, and N. Ferry Cell lineage study in the liver using retroviral mediated gene transfer. Evidence against the streaming of hepatocytes in normal liver Am J Pathol 144 1994 896 905
    • (1994) Am J Pathol , vol.144 , pp. 896-905
    • Bralet, M.P.1    Branchereau, S.2    Brechot, C.3    Ferry, N.4
  • 13
    • 0008973741 scopus 로고
    • Determination of the hepatic arterial blood flow and oxygen supply in man by clamping the hepatic artery during surgery
    • N. Tygstrup, K. Winkler, K. Mellemgaard, and M. Andreassen Determination of the hepatic arterial blood flow and oxygen supply in man by clamping the hepatic artery during surgery J Clin Invest 41 1962 447 454
    • (1962) J Clin Invest , vol.41 , pp. 447-454
    • Tygstrup, N.1    Winkler, K.2    Mellemgaard, K.3    Andreassen, M.4
  • 14
    • 0037191930 scopus 로고    scopus 로고
    • New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism
    • A. Cadoret, C. Ovejero, B. Terris, E. Souil, L. Levy, and W.H. Lamers New targets of beta-catenin signaling in the liver are involved in the glutamine metabolism Oncogene 21 2002 8293 8301
    • (2002) Oncogene , vol.21 , pp. 8293-8301
    • Cadoret, A.1    Ovejero, C.2    Terris, B.3    Souil, E.4    Levy, L.5    Lamers, W.H.6
  • 15
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • H. Clevers Wnt/beta-catenin signaling in development and disease Cell 127 2006 469 480
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 16
    • 62849106337 scopus 로고    scopus 로고
    • Beta-catenin hits chromatin: Regulation of Wnt target gene activation
    • C. Mosimann, G. Hausmann, and K. Basler Beta-catenin hits chromatin: regulation of Wnt target gene activation Nat Rev Mol Cell Biol 10 2009 276 286
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 276-286
    • Mosimann, C.1    Hausmann, G.2    Basler, K.3
  • 19
    • 0032525836 scopus 로고    scopus 로고
    • Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3
    • Y. Miyoshi, K. Iwao, Y. Nagasawa, T. Aihara, Y. Sasaki, and S. Imaoka Activation of the beta-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3 Cancer Res 58 1998 2524 2527
    • (1998) Cancer Res , vol.58 , pp. 2524-2527
    • Miyoshi, Y.1    Iwao, K.2    Nagasawa, Y.3    Aihara, T.4    Sasaki, Y.5    Imaoka, S.6
  • 20
    • 34347385893 scopus 로고    scopus 로고
    • Cholestasis is a marker for hepatocellular carcinomas displaying beta-catenin mutations
    • V. Audard, G. Grimber, C. Elie, B. Radenen, A. Audebourg, and F. Letourneur Cholestasis is a marker for hepatocellular carcinomas displaying beta-catenin mutations J Pathol 212 2007 345 352
    • (2007) J Pathol , vol.212 , pp. 345-352
    • Audard, V.1    Grimber, G.2    Elie, C.3    Radenen, B.4    Audebourg, A.5    Letourneur, F.6
  • 21
    • 33846463379 scopus 로고    scopus 로고
    • Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
    • S. Boyault, D.S. Rickman, A. de Reynies, C. Balabaud, S. Rebouissou, and E. Jeannot Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets Hepatology 45 2007 42 52
    • (2007) Hepatology , vol.45 , pp. 42-52
    • Boyault, S.1    Rickman, D.S.2    De Reynies, A.3    Balabaud, C.4    Rebouissou, S.5    Jeannot, E.6
  • 22
    • 10344254872 scopus 로고    scopus 로고
    • Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas
    • S. Colnot, T. Decaens, M. Niwa-Kawakita, C. Godard, G. Hamard, and A. Kahn Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas Proc Natl Acad Sci USA 101 2004 17216 17221
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 17216-17221
    • Colnot, S.1    Decaens, T.2    Niwa-Kawakita, M.3    Godard, C.4    Hamard, G.5    Kahn, A.6
  • 25
    • 55249106920 scopus 로고    scopus 로고
    • Wnt/beta-catenin pathway in hepatocellular carcinoma pathogenesis and liver physiology
    • C. Cavard, S. Colnot, V. Audard, S. Benhamouche, L. Finzi, and C. Torre Wnt/beta-catenin pathway in hepatocellular carcinoma pathogenesis and liver physiology Future Oncol 4 2008 647 660
    • (2008) Future Oncol , vol.4 , pp. 647-660
    • Cavard, C.1    Colnot, S.2    Audard, V.3    Benhamouche, S.4    Finzi, L.5    Torre, C.6
  • 26
    • 33645989449 scopus 로고    scopus 로고
    • Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice
    • S. Sekine, B.Y. Lan, M. Bedolli, S. Feng, and M. Hebrok Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice Hepatology 43 2006 817 825
    • (2006) Hepatology , vol.43 , pp. 817-825
    • Sekine, S.1    Lan, B.Y.2    Bedolli, M.3    Feng, S.4    Hebrok, M.5
  • 27
    • 66449102968 scopus 로고    scopus 로고
    • Inducibility of drug-metabolizing enzymes by xenobiotics in mice with liver-specific knockout of Ctnnb1
    • A. Braeuning, R. Sanna, J. Huelsken, and M. Schwarz Inducibility of drug-metabolizing enzymes by xenobiotics in mice with liver-specific knockout of Ctnnb1 Drug Metab Dispos 37 2009 1138 1145
    • (2009) Drug Metab Dispos , vol.37 , pp. 1138-1145
    • Braeuning, A.1    Sanna, R.2    Huelsken, J.3    Schwarz, M.4
  • 28
    • 79551686173 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling activates and determines hepatic zonal expression of glutathione S-transferases in mouse liver
    • S. Giera, A. Braeuning, C. Kohle, W. Bursch, U. Metzger, and A. Buchmann Wnt/beta-catenin signaling activates and determines hepatic zonal expression of glutathione S-transferases in mouse liver Toxicol Sci 115 2010 22 33
    • (2010) Toxicol Sci , vol.115 , pp. 22-33
    • Giera, S.1    Braeuning, A.2    Kohle, C.3    Bursch, W.4    Metzger, U.5    Buchmann, A.6
  • 29
    • 68549117276 scopus 로고    scopus 로고
    • Proteomic analysis of beta-catenin activation in mouse liver by DIGE analysis identifies glucose metabolism as a new target of the Wnt pathway
    • P. Chafey, L. Finzi, R. Boisgard, M. Cauzac, G. Clary, and C. Broussard Proteomic analysis of beta-catenin activation in mouse liver by DIGE analysis identifies glucose metabolism as a new target of the Wnt pathway Proteomics 9 2009 3889 3900
    • (2009) Proteomics , vol.9 , pp. 3889-3900
    • Chafey, P.1    Finzi, L.2    Boisgard, R.3    Cauzac, M.4    Clary, G.5    Broussard, C.6
  • 30
    • 76149088123 scopus 로고    scopus 로고
    • Liver-specific beta-catenin knockout mice exhibit defective bile acid and cholesterol homeostasis and increased susceptibility to diet-induced steatohepatitis
    • J. Behari, T.H. Yeh, L. Krauland, W. Otruba, B. Cieply, and B. Hauth Liver-specific beta-catenin knockout mice exhibit defective bile acid and cholesterol homeostasis and increased susceptibility to diet-induced steatohepatitis Am J Pathol 176 2010 744 753
    • (2010) Am J Pathol , vol.176 , pp. 744-753
    • Behari, J.1    Yeh, T.H.2    Krauland, L.3    Otruba, W.4    Cieply, B.5    Hauth, B.6
  • 31
    • 0032718124 scopus 로고    scopus 로고
    • Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation
    • R. DasGupta, and E. Fuchs Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation Development 126 1999 4557 4568
    • (1999) Development , vol.126 , pp. 4557-4568
    • Dasgupta, R.1    Fuchs, E.2
  • 32
    • 33947164297 scopus 로고    scopus 로고
    • GFP transgenic mice reveal active canonical Wnt signal in neonatal brain and in adult liver and spleen
    • A. Moriyama, I. Kii, T. Sunabori, S. Kurihara, I. Takayama, and M. Shimazaki GFP transgenic mice reveal active canonical Wnt signal in neonatal brain and in adult liver and spleen Genesis 45 2007 90 100
    • (2007) Genesis , vol.45 , pp. 90-100
    • Moriyama, A.1    Kii, I.2    Sunabori, T.3    Kurihara, S.4    Takayama, I.5    Shimazaki, M.6
  • 33
    • 33847749416 scopus 로고    scopus 로고
    • Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy
    • S. Sekine, P.J. Gutierrez, B.Y. Lan, S. Feng, and M. Hebrok Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy Hepatology 45 2007 361 368
    • (2007) Hepatology , vol.45 , pp. 361-368
    • Sekine, S.1    Gutierrez, P.J.2    Lan, B.Y.3    Feng, S.4    Hebrok, M.5
  • 35
    • 35648940341 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in murine hepatic transit amplifying progenitor cells
    • M. Hu, M. Kurobe, Y.J. Jeong, C. Fuerer, S. Ghole, and R. Nusse Wnt/beta-catenin signaling in murine hepatic transit amplifying progenitor cells Gastroenterology 133 2007 1579 1591
    • (2007) Gastroenterology , vol.133 , pp. 1579-1591
    • Hu, M.1    Kurobe, M.2    Jeong, Y.J.3    Fuerer, C.4    Ghole, S.5    Nusse, R.6
  • 36
    • 67649240480 scopus 로고    scopus 로고
    • Mechanisms of liver development: Concepts for understanding liver disorders and design of novel therapies
    • F.P. Lemaigre Mechanisms of liver development: concepts for understanding liver disorders and design of novel therapies Gastroenterology 137 2009 62 79
    • (2009) Gastroenterology , vol.137 , pp. 62-79
    • Lemaigre, F.P.1
  • 37
    • 33747033130 scopus 로고    scopus 로고
    • Mesodermal Wnt2b signalling positively regulates liver specification
    • E.A. Ober, H. Verkade, H.A. Field, and D.Y. Stainier Mesodermal Wnt2b signalling positively regulates liver specification Nature 442 2006 688 691
    • (2006) Nature , vol.442 , pp. 688-691
    • Ober, E.A.1    Verkade, H.2    Field, H.A.3    Stainier, D.Y.4
  • 38
    • 34347341779 scopus 로고    scopus 로고
    • Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development
    • V.A. McLin, S.A. Rankin, and A.M. Zorn Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development Development 134 2007 2207 2217
    • (2007) Development , vol.134 , pp. 2207-2217
    • McLin, V.A.1    Rankin, S.A.2    Zorn, A.M.3
  • 39
    • 34250820372 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling and cardiogenesis: Timing does matter
    • E. Tzahor Wnt/beta-catenin signaling and cardiogenesis: timing does matter Dev Cell 13 2007 10 13
    • (2007) Dev Cell , vol.13 , pp. 10-13
    • Tzahor, E.1
  • 40
    • 38649093310 scopus 로고    scopus 로고
    • Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate
    • T. Decaens, C. Godard, A. de Reynies, D.S. Rickman, F. Tronche, and J.P. Couty Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate Hepatology 47 2008 247 258
    • (2008) Hepatology , vol.47 , pp. 247-258
    • Decaens, T.1    Godard, C.2    De Reynies, A.3    Rickman, D.S.4    Tronche, F.5    Couty, J.P.6
  • 41
    • 43949133408 scopus 로고    scopus 로고
    • Beta-catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development
    • X. Tan, Y. Yuan, G. Zeng, U. Apte, M.D. Thompson, and B. Cieply Beta-catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development Hepatology 47 2008 1667 1679
    • (2008) Hepatology , vol.47 , pp. 1667-1679
    • Tan, X.1    Yuan, Y.2    Zeng, G.3    Apte, U.4    Thompson, M.D.5    Cieply, B.6
  • 43
    • 33846705750 scopus 로고    scopus 로고
    • Epithelial stem cells: Turning over new leaves
    • C. Blanpain, V. Horsley, and E. Fuchs Epithelial stem cells: turning over new leaves Cell 128 2007 445 458
    • (2007) Cell , vol.128 , pp. 445-458
    • Blanpain, C.1    Horsley, V.2    Fuchs, E.3
  • 44
    • 73949116718 scopus 로고    scopus 로고
    • Organ patterning in the adult stage: The role of Wnt/beta-catenin signaling in liver zonation and beyond
    • R. Gebhardt, and A. Hovhannisyan Organ patterning in the adult stage: the role of Wnt/beta-catenin signaling in liver zonation and beyond Dev Dyn 239 2010 45 55
    • (2010) Dev Dyn , vol.239 , pp. 45-55
    • Gebhardt, R.1    Hovhannisyan, A.2
  • 45
    • 33846450620 scopus 로고    scopus 로고
    • Wnt'er in liver: Expression of Wnt and frizzled genes in mouse
    • G. Zeng, F. Awan, W. Otruba, P. Muller, U. Apte, and X. Tan Wnt'er in liver: expression of Wnt and frizzled genes in mouse Hepatology 45 2007 195 204
    • (2007) Hepatology , vol.45 , pp. 195-204
    • Zeng, G.1    Awan, F.2    Otruba, W.3    Muller, P.4    Apte, U.5    Tan, X.6
  • 46
    • 77954055939 scopus 로고    scopus 로고
    • Shaping morphogen gradients by proteoglycans
    • D. Yan, and X. Lin Shaping morphogen gradients by proteoglycans Cold Spring Harb Perspect Biol 1 2009 a002493
    • (2009) Cold Spring Harb Perspect Biol , vol.1 , pp. 002493
    • Yan, D.1    Lin, X.2
  • 47
    • 33646592268 scopus 로고    scopus 로고
    • Wnt gradient formation requires retromer function in Wnt-producing cells
    • D.Y. Coudreuse, G. Roel, M.C. Betist, O. Destree, and H.C. Korswagen Wnt gradient formation requires retromer function in Wnt-producing cells Science 312 2006 921 924
    • (2006) Science , vol.312 , pp. 921-924
    • Coudreuse, D.Y.1    Roel, G.2    Betist, M.C.3    Destree, O.4    Korswagen, H.C.5
  • 49
    • 18344378499 scopus 로고    scopus 로고
    • Lipoprotein particles are required for hedgehog and wingless signalling
    • D. Panakova, H. Sprong, E. Marois, C. Thiele, and S. Eaton Lipoprotein particles are required for hedgehog and wingless signalling Nature 435 2005 58 65
    • (2005) Nature , vol.435 , pp. 58-65
    • Panakova, D.1    Sprong, H.2    Marois, E.3    Thiele, C.4    Eaton, S.5
  • 50
    • 46049104677 scopus 로고    scopus 로고
    • Wnt9a secreted from the walls of hepatic sinusoids is essential for morphogenesis, proliferation, and glycogen accumulation of chick hepatic epithelium
    • K. Matsumoto, R. Miki, M. Nakayama, N. Tatsumi, and Y. Yokouchi Wnt9a secreted from the walls of hepatic sinusoids is essential for morphogenesis, proliferation, and glycogen accumulation of chick hepatic epithelium Dev Biol 319 2008 234 247
    • (2008) Dev Biol , vol.319 , pp. 234-247
    • Matsumoto, K.1    Miki, R.2    Nakayama, M.3    Tatsumi, N.4    Yokouchi, Y.5
  • 51
    • 40949117599 scopus 로고    scopus 로고
    • Wnt2 acts as a cell type-specific, autocrine growth factor in rat hepatic sinusoidal endothelial cells cross-stimulating the VEGF pathway
    • D. Klein, A. Demory, F. Peyre, J. Kroll, H.G. Augustin, and W. Helfrich Wnt2 acts as a cell type-specific, autocrine growth factor in rat hepatic sinusoidal endothelial cells cross-stimulating the VEGF pathway Hepatology 47 2008 1018 1031
    • (2008) Hepatology , vol.47 , pp. 1018-1031
    • Klein, D.1    Demory, A.2    Peyre, F.3    Kroll, J.4    Augustin, H.G.5    Helfrich, W.6
  • 52
    • 42149131539 scopus 로고    scopus 로고
    • Adenomatous polyposis coli is present near the minimal level required for accurate graded responses to the wingless morphogen
    • H. Benchabane, E.G. Hughes, C.M. Takacs, J.R. Baird, and Y. Ahmed Adenomatous polyposis coli is present near the minimal level required for accurate graded responses to the wingless morphogen Development 135 2008 963 971
    • (2008) Development , vol.135 , pp. 963-971
    • Benchabane, H.1    Hughes, E.G.2    Takacs, C.M.3    Baird, J.R.4    Ahmed, Y.5
  • 53
    • 76749147440 scopus 로고    scopus 로고
    • Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo
    • M. Buchert, D. Athineos, H.E. Abud, Z.D. Burke, M.C. Faux, and M.S. Samuel Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo PLoS Genet 6 2010 e1000816
    • (2010) PLoS Genet , vol.6
    • Buchert, M.1    Athineos, D.2    Abud, H.E.3    Burke, Z.D.4    Faux, M.C.5    Samuel, M.S.6
  • 54
    • 0037096906 scopus 로고    scopus 로고
    • The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade
    • C. Albuquerque, C. Breukel, R. van der Luijt, P. Fidalgo, P. Lage, and F.J. Slors The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade Hum Mol Genet 11 2002 1549 1560
    • (2002) Hum Mol Genet , vol.11 , pp. 1549-1560
    • Albuquerque, C.1    Breukel, C.2    Van Der Luijt, R.3    Fidalgo, P.4    Lage, P.5    Slors, F.J.6
  • 55
    • 33750726092 scopus 로고    scopus 로고
    • Conditional deletion of beta-catenin reveals its role in liver growth and regeneration
    • X. Tan, J. Behari, B. Cieply, G.K. Michalopoulos, and S.P. Monga Conditional deletion of beta-catenin reveals its role in liver growth and regeneration Gastroenterology 131 2006 1561 1572
    • (2006) Gastroenterology , vol.131 , pp. 1561-1572
    • Tan, X.1    Behari, J.2    Cieply, B.3    Michalopoulos, G.K.4    Monga, S.P.5
  • 56
    • 78649266141 scopus 로고    scopus 로고
    • Transcription dynamics in a physiological process: Beta-catenin signaling directs liver metabolic zonation
    • C. Torre, C. Perret, and S. Colnot Transcription dynamics in a physiological process: beta-catenin signaling directs liver metabolic zonation Int J Biochem Cell Biol 2009 [E-pub ahead of print.]
    • (2009) Int J Biochem Cell Biol
    • Torre, C.1    Perret, C.2    Colnot, S.3
  • 58
    • 0036531817 scopus 로고    scopus 로고
    • Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin
    • N. Harada, H. Miyoshi, N. Murai, H. Oshima, Y. Tamai, and M. Oshima Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin Cancer Res 62 2002 1971 1977
    • (2002) Cancer Res , vol.62 , pp. 1971-1977
    • Harada, N.1    Miyoshi, H.2    Murai, N.3    Oshima, H.4    Tamai, Y.5    Oshima, M.6
  • 59
    • 0031660963 scopus 로고    scopus 로고
    • Zonal location of compensatory hepatocyte proliferation following chemically induced hepatotoxicity in rats and humans
    • V.M. Lee, R.G. Cameron, and M.C. Archer Zonal location of compensatory hepatocyte proliferation following chemically induced hepatotoxicity in rats and humans Toxicol Pathol 26 1998 621 627
    • (1998) Toxicol Pathol , vol.26 , pp. 621-627
    • Lee, V.M.1    Cameron, R.G.2    Archer, M.C.3
  • 60
    • 31544474342 scopus 로고    scopus 로고
    • Overexpression of regenerating islet-derived 1 alpha and 3 alpha genes in human primary liver tumors with beta-catenin mutations
    • C. Cavard, B. Terris, G. Grimber, L. Christa, V. Audard, and B. Radenen-Bussiere Overexpression of regenerating islet-derived 1 alpha and 3 alpha genes in human primary liver tumors with beta-catenin mutations Oncogene 25 2006 599 608
    • (2006) Oncogene , vol.25 , pp. 599-608
    • Cavard, C.1    Terris, B.2    Grimber, G.3    Christa, L.4    Audard, V.5    Radenen-Bussiere, B.6
  • 63
    • 57749087003 scopus 로고    scopus 로고
    • β-Catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver
    • K.R. Reed, D. Athineos, V.S. Meniel, J.A. Wilkins, R.A. Ridgway, and Z.D. Burke β-Catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver Proc Natl Acad Sci USA 105 2008 18919 18923
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 18919-18923
    • Reed, K.R.1    Athineos, D.2    Meniel, V.S.3    Wilkins, J.A.4    Ridgway, R.A.5    Burke, Z.D.6
  • 65
    • 34548458190 scopus 로고    scopus 로고
    • Serum components and activated Ha-ras antagonize expression of perivenous marker genes stimulated by beta-catenin signaling in mouse hepatocytes
    • A. Braeuning, M. Menzel, E.M. Kleinschnitz, N. Harada, Y. Tamai, and C. Kohle Serum components and activated Ha-ras antagonize expression of perivenous marker genes stimulated by beta-catenin signaling in mouse hepatocytes FEBS J 274 2007 4766 4777
    • (2007) FEBS J , vol.274 , pp. 4766-4777
    • Braeuning, A.1    Menzel, M.2    Kleinschnitz, E.M.3    Harada, N.4    Tamai, Y.5    Kohle, C.6
  • 66
    • 1642535593 scopus 로고    scopus 로고
    • Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations
    • N. Harada, H. Oshima, M. Katoh, Y. Tamai, M. Oshima, and M.M. Taketo Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutations Cancer Res 64 2004 48 54
    • (2004) Cancer Res , vol.64 , pp. 48-54
    • Harada, N.1    Oshima, H.2    Katoh, M.3    Tamai, Y.4    Oshima, M.5    Taketo, M.M.6
  • 67
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • O. Tetsu, and F. McCormick Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells Nature 398 1999 422 426
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 69
    • 33744795211 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver
    • M.A. Battle, G. Konopka, F. Parviz, A.L. Gaggl, C. Yang, and F.M. Sladek Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver Proc Natl Acad Sci USA 103 2006 8419 8424
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 8419-8424
    • Battle, M.A.1    Konopka, G.2    Parviz, F.3    Gaggl, A.L.4    Yang, C.5    Sladek, F.M.6
  • 70
    • 0035141324 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis
    • G.P. Hayhurst, Y.H. Lee, G. Lambert, J.M. Ward, and F.J. Gonzalez Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis Mol Cell Biol 21 2001 1393 1403
    • (2001) Mol Cell Biol , vol.21 , pp. 1393-1403
    • Hayhurst, G.P.1    Lee, Y.H.2    Lambert, G.3    Ward, J.M.4    Gonzalez, F.J.5
  • 71
    • 0037067687 scopus 로고    scopus 로고
    • Defective ureagenesis in mice carrying a liver-specific disruption of hepatocyte nuclear factor 4alpha (HNF4alpha). HNF4alpha regulates ornithine transcarbamylase in vivo
    • Y. Inoue, G.P. Hayhurst, J. Inoue, M. Mori, and F.J. Gonzalez Defective ureagenesis in mice carrying a liver-specific disruption of hepatocyte nuclear factor 4alpha (HNF4alpha). HNF4alpha regulates ornithine transcarbamylase in vivo J Biol Chem 277 2002 25257 25265
    • (2002) J Biol Chem , vol.277 , pp. 25257-25265
    • Inoue, Y.1    Hayhurst, G.P.2    Inoue, J.3    Mori, M.4    Gonzalez, F.J.5
  • 73
    • 0038757830 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis
    • F. Parviz, C. Matullo, W.D. Garrison, L. Savatski, J.W. Adamson, and G. Ning Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis Nat Genet 34 2003 292 296
    • (2003) Nat Genet , vol.34 , pp. 292-296
    • Parviz, F.1    Matullo, C.2    Garrison, W.D.3    Savatski, L.4    Adamson, J.W.5    Ning, G.6
  • 74
    • 0030808426 scopus 로고    scopus 로고
    • Zonal distribution of transcripts of four hepatic transcription factors in the mature rat liver
    • K.O. Lindros, T. Oinonen, J. Issakainen, P. Nagy, and S.S. Thorgeirsson Zonal distribution of transcripts of four hepatic transcription factors in the mature rat liver Cell Biol Toxicol 13 1997 257 262
    • (1997) Cell Biol Toxicol , vol.13 , pp. 257-262
    • Lindros, K.O.1    Oinonen, T.2    Issakainen, J.3    Nagy, P.4    Thorgeirsson, S.S.5
  • 75
  • 76
  • 77
    • 0034283030 scopus 로고    scopus 로고
    • Beta-catenin affects androgen receptor transcriptional activity and ligand specificity
    • C.I. Truica, S. Byers, and E.P. Gelmann Beta-catenin affects androgen receptor transcriptional activity and ligand specificity Cancer Res 60 2000 4709 4713
    • (2000) Cancer Res , vol.60 , pp. 4709-4713
    • Truica, C.I.1    Byers, S.2    Gelmann, E.P.3
  • 78
    • 28844439793 scopus 로고    scopus 로고
    • Interaction of nuclear receptors with the Wnt/beta-catenin/Tcf signaling axis: Wnt you like to know?
    • D.J. Mulholland, S. Dedhar, G.A. Coetzee, and C.C. Nelson Interaction of nuclear receptors with the Wnt/beta-catenin/Tcf signaling axis: Wnt you like to know? Endocr Rev 26 2005 898 915
    • (2005) Endocr Rev , vol.26 , pp. 898-915
    • Mulholland, D.J.1    Dedhar, S.2    Coetzee, G.A.3    Nelson, C.C.4
  • 79
    • 33746483284 scopus 로고    scopus 로고
    • Functional interaction between peroxisome proliferator-activated receptor gamma and beta-catenin
    • J. Liu, H. Wang, Y. Zuo, and S.R. Farmer Functional interaction between peroxisome proliferator-activated receptor gamma and beta-catenin Mol Cell Biol 26 2006 5827 5837
    • (2006) Mol Cell Biol , vol.26 , pp. 5827-5837
    • Liu, J.1    Wang, H.2    Zuo, Y.3    Farmer, S.R.4
  • 81
    • 13444304475 scopus 로고    scopus 로고
    • A beta-catenin-dependent pathway regulates expression of cytochrome P450 isoforms in mouse liver tumors
    • S. Loeppen, C. Koehle, A. Buchmann, and M. Schwarz A beta-catenin- dependent pathway regulates expression of cytochrome P450 isoforms in mouse liver tumors Carcinogenesis 26 2005 239 248
    • (2005) Carcinogenesis , vol.26 , pp. 239-248
    • Loeppen, S.1    Koehle, C.2    Buchmann, A.3    Schwarz, M.4
  • 82
    • 70349172032 scopus 로고    scopus 로고
    • Should i stay or should i go: Beta-catenin decides under stress
    • D. Hoogeboom, and B.M. Burgering Should I stay or should I go: beta-catenin decides under stress Biochim Biophys Acta 1796 2 2009 63 74
    • (2009) Biochim Biophys Acta , vol.1796 , Issue.2 , pp. 63-74
    • Hoogeboom, D.1    Burgering, B.M.2
  • 83
    • 27844497945 scopus 로고    scopus 로고
    • FOXO transcription factors at the interface between longevity and tumor suppression
    • E.L. Greer, and A. Brunet FOXO transcription factors at the interface between longevity and tumor suppression Oncogene 24 2005 7410 7425
    • (2005) Oncogene , vol.24 , pp. 7410-7425
    • Greer, E.L.1    Brunet, A.2
  • 85
    • 0033960898 scopus 로고    scopus 로고
    • Oxygen: Modulator of metabolic zonation and disease of the liver
    • K. Jungermann, and T. Kietzmann Oxygen: modulator of metabolic zonation and disease of the liver Hepatology 31 2000 255 260
    • (2000) Hepatology , vol.31 , pp. 255-260
    • Jungermann, K.1    Kietzmann, T.2
  • 86
    • 0035868277 scopus 로고    scopus 로고
    • Perivenous expression of the mRNA of the three hypoxia-inducible factor alpha-subunits, HIF1alpha, HIF2alpha and HIF3alpha, in rat liver
    • T. Kietzmann, Y. Cornesse, K. Brechtel, S. Modaressi, and K. Jungermann Perivenous expression of the mRNA of the three hypoxia-inducible factor alpha-subunits, HIF1alpha, HIF2alpha and HIF3alpha, in rat liver Biochem J 354 2001 531 537
    • (2001) Biochem J , vol.354 , pp. 531-537
    • Kietzmann, T.1    Cornesse, Y.2    Brechtel, K.3    Modaressi, S.4    Jungermann, K.5
  • 87
    • 0037315337 scopus 로고    scopus 로고
    • Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs
    • M.S. Wiesener, J.S. Jurgensen, C. Rosenberger, C.K. Scholze, J.H. Horstrup, and C. Warnecke Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs FASEB J 17 2003 271 273
    • (2003) FASEB J , vol.17 , pp. 271-273
    • Wiesener, M.S.1    Jurgensen, J.S.2    Rosenberger, C.3    Scholze, C.K.4    Horstrup, J.H.5    Warnecke, C.6
  • 88
    • 33947217823 scopus 로고    scopus 로고
    • Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia
    • A. Kaidi, A.C. Williams, and C. Paraskeva Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia Nat Cell Biol 9 2007 210 217
    • (2007) Nat Cell Biol , vol.9 , pp. 210-217
    • Kaidi, A.1    Williams, A.C.2    Paraskeva, C.3
  • 90
    • 34047157076 scopus 로고    scopus 로고
    • Zonal gene expression in mouse liver resembles expression patterns of Ha-ras and beta-catenin mutated hepatomas
    • A. Braeuning, C. Ittrich, C. Kohle, A. Buchmann, and M. Schwarz Zonal gene expression in mouse liver resembles expression patterns of Ha-ras and beta-catenin mutated hepatomas Drug Metab Dispos 35 2007 503 507
    • (2007) Drug Metab Dispos , vol.35 , pp. 503-507
    • Braeuning, A.1    Ittrich, C.2    Kohle, C.3    Buchmann, A.4    Schwarz, M.5
  • 91
    • 9644254191 scopus 로고    scopus 로고
    • Application of comparative functional genomics to identify best-fit mouse models to study human cancer
    • J.S. Lee, I.S. Chu, A. Mikaelyan, D.F. Calvisi, J. Heo, and J.K. Reddy Application of comparative functional genomics to identify best-fit mouse models to study human cancer Nat Genet 36 2004 1306 1311
    • (2004) Nat Genet , vol.36 , pp. 1306-1311
    • Lee, J.S.1    Chu, I.S.2    Mikaelyan, A.3    Calvisi, D.F.4    Heo, J.5    Reddy, J.K.6
  • 92
    • 33846846541 scopus 로고    scopus 로고
    • Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomas
    • J. Zucman-Rossi, S. Benhamouche, C. Godard, S. Boyault, G. Grimber, and C. Balabaud Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomas Oncogene 26 2007 774 780
    • (2007) Oncogene , vol.26 , pp. 774-780
    • Zucman-Rossi, J.1    Benhamouche, S.2    Godard, C.3    Boyault, S.4    Grimber, G.5    Balabaud, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.