The role of nitric oxide in the modulation of hepatic microcirculation and tissue oxygenation in an experimental model of hepatic steatosis

Microcirculation

Volumn 10, Issue 6, 2003, Pages 447-456

  Ijaz, Samia ^a   Yang, Wenxuan ^a   Winslet, Marc C ^a,b   Seifalian, Alexander M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ROYAL FREE LONDON NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Blood flow; Fatty liver; Ischaemia reperfusion injury; Liver disease; Microcirculation; Perfusion; Steatosis; Transplantation

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; AFLATOXIN; BLEOMYCIN; CORTICOSTEROID; DIDANOSINE; FIALURIDINE; METHOTREXATE; PHOSPHORUS; SALICYLIC ACID; TETRACYCLINE; TRIACYLGLYCEROL; VALPROIC ACID; WARFARIN; ZIDOVUDINE;

ALCOHOL LIVER DISEASE; CELL VOLUME; CORRELATION ANALYSIS; CYTOPLASM; DISEASE SEVERITY; DRUG EFFECT; FATTY LIVER; HEPATIC ARTERY; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; LIVER BIOPSY; LIVER BLOOD FLOW; LIVER CELL; LIVER CIRCULATION; LIVER DYSFUNCTION; LIVER SINUSOID; LIVER TRANSPLANTATION; MICROCIRCULATION; NONHUMAN; OBESITY; ORGAN DONOR; PORTAL VEIN BLOOD FLOW; PRIORITY JOURNAL; REPERFUSION INJURY; REVIEW;

ANIMALS; FATTY LIVER; HUMANS; LIPID METABOLISM; LIVER; LIVER CIRCULATION; LIVER TRANSPLANTATION; MICROCIRCULATION; REPERFUSION INJURY; TISSUE DONORS;

EID: 3442893625     PISSN: 10739688     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mn.7800206     Document Type: Review

References (53)

1. Akamatsu K, Nishinobu M, Ohuchi T, Tada K, Ohta Y. (1993). Effect of chronic alcohol intake on rat liver microcirculation assessed by the multiple indicator dilution technique. Alcohol Alcohol Suppl 1A:53-58
2. Ballet F. (1990). Hepatic circulation: potential for therapeutic intervention. Pharmacol Ther 47:281-328
3. Bauer M, Zhang JX, Bauer I. Clemens MG. (1994). ET-1 induced alterations of hepatic microcirculation: sinusoidal and extrasinusoidal sites of action. Am J Physiol 267:G143-G149
4. Behrns KE., Tsiotos GG, DeSouza NF, Krishna MK, Ludwig J, Nagorney DM. (1998). Hepatic steatosis as a potential risk factor for major hepatic resection. J Gastrointest Surg 2:292-298
5. Burt AD, MacSween RNM, Peters TJ, Simpson KJ. (1991). Nonalcoholic Fatty Liver. Causes and Complications. Oxford: Oxford University Press, p 863-872
6. Burt AD, Mutton A, Day GP. (1998). Diagnosis and interpretation of steatosis and steatohepatitis. Semin Diagn Pathol 15:246-258
7. Caraceni P, Nardo B, Domenicali M, Turi P, Vici M, Simoncini M, De Maria N, Trevisani F, Van Thiel DH, Derenzini M, Cavallari A, Bernardi M. (1999). Ischemia-reperfusion injury in rat fatty liver: role of nutritional status. Hepatology 29:1139-1146
8. Clemens MG, Zhang JX. (1999). Regulation of sinusoidal perfusion: in vivo methodology and control by endothelins. Semin Liver Dis 19:383-396
9. D'Alessandro AM, Kalayoglu M, Sollinger HW, Hoffmann RM, Reed A, Knechtle SJ, Pirsch JD, Hafez GR, Lorentzen D, Belzer FO. (1991). The predictive value of donor liver biopsies for the development of primary nonfunction after orthotopic liver transplantation. Transplantation 51:157-163
10. Day CP. (2002). Non-alcoholic steatohepatitis (NASH): where are we now and where are we going? Gut 50:585-588
11. Day CP, James OF. (1998). Hepatic steatosis: innocent bystander or guilty party? Hepatology 27:1463-1466
12. Fromenty B., Berson A, Pessayre D. (1997). Microvesicular steatosis and steatohepatitis: role of mitochondrial dysfunction and lipid peroxidation. J Hepatol 26:13-22
13. Fukumori T, Ohkohchi N, Tsukamoto S, Satomi S. (1999). The mechanism of injury in a steatotic liver graft during cold preservation. Transplantation 67: 195-200
14. Hakamada K, Sasaki M, Takahashi K, Umehara Y, Konn M. (1997). Sinusoidal flow block after warm ischemia in rats with diet-induced fatty liver. J Surg Res 70:12-20
15. Hall P. de la M. (2002). Alcoholic liver disease. In: MacSween RNM, Burt AD, Portmann BC, Ishak KG, Scheuer PJ, Anthony PP, editors. Pathology of the Liver. 4th edition. London: Churchill Livingstone, p 273-311
16. Harrison SA, Kadakia S, Lang KA, Schenker S. (2002). Nonalcoholic steatohepatitis: what we know in the new millennium. Am J Gastroenterol 97:2714-2724
17. Hayashi M, Tokunaga Y, Fujita T, Tanaka K, Yamaoka Y, Ozawa K. (1993). The effects of cold preservation on steatotic graft viability in rat liver transplantation. Transplantation 56:282-287
18. Karube H, Masuda H, Hayashi S, Ishii Y, Nemoto N. (2000). Fatty liver suppressed the angiogenesis in liver metastatic lesions. Hepatogastroenterology 47: 1541-1545
19. Koneru B, Dikdan G. (2002). Hepatic steatosis and liver transplantation current clinical and experimental perspectives. Transplantation 73:325-330
20. Koteish A, Diehl AM. (2001). Animal models of steatosis. Semin Liver Dis 21:89-104
21. Lewis GF. (1997). Fatty acid regulation of very low density lipoprotein production. Curr Opin Lipidol 8: 146-153
22. McCuskey RS. (2000). Morphological mechanisms for regulating blood flow through hepatic sinusoids. Liver 20:3-7
23. McCuskey RS, Reilly FD. (1993). Hepatic microvasculature: dynamic structure and its regulation. Semin Liver Dis 13:1-12
24. Nakano H, Nagasaki H, Barama A, Boudjema K, Jaeck D, Kumada K, Tatsuno M, Baek Y, Kitamura N, Suzuki T, Yamaguchi M. (1997). The effects of N-acetylcysteine and auti-intercellular adhesion molecule-1 monoclonal antibody against ischemia-reperfusion injury of the rat steatotic liver produced by a choline-methionine-deficient diet. Hepatology 26:670-678
25. Oda M, Han JY, Yokomori H. (2000). Local regulators of hepatic sinusoidal microcirculation: recent advances. Clin Hemorheol Microcirc 23:85-94
26. Pannen BH. (2002). New insights into the regulation of hepatic blood flow after ischemia and reperfusion. Anesth Analg 94:1448-1457
27. Saleh J, Sniderman AD, Cianflone K. (1999). Regulation of plasma fatty acid metabolism. Clin Chim Acta 286:163-180
28. Sato N. Eguchi H, Inoue A, Matsumura T, Kawano S, Kamada T. (1986). Hepatic microcirculation in Zucker fatty rats. Adv Exp Med Biol 200:477-483
29. Seifalian AM, Chidambaram V, Rolles K, Davidson BR. (1998). In vivo demonstration of impaired microcirculation in steatotic human liver grafts. Liver Transpl Surg 4:71-77
30. Seifalian AM, El Desoky A, Davidson BR. (2001). Hepatic indocyanine green uptake and excretion in a rabbit model of steatosis. Eur Surg Res 33:193-201
31. Seifalian AM., Howell K, Stansby G, Jackson AE, Hamilton G, Black CM. (1993). Laser Doppler perfusion imaging: a new technique for measuring skin blood flow in rheumatology. Br J Rheumatol 32:938-939
32. Seifalian AM, Mallet SV, Rolles K, Davidson BR. (1997). Hepatic microcirculation during human orthotopic liver transplantation. Br J Surg 84:1391-1395
33. Seifalian AM, Piasecki C, Agarwal A, Davidson BR. (1999). The effect of graded steatosis on flow in the hepatic parenchymal microcirculation. Transplantation 68:780-784
34. Selzner M, Clavien PA. (2001). Fatty liver in liver transplantation and surgery. Semin Liver Dis 21:105-113
35. Selzner M, Rudiger HA, Sindram D, Madden J, Clavien PA. (2000). Mechanisms of ischemic injury are different in the steatotic and normal rat liver. Hepatology 32:1280-1288
36. Serafin A, Rosello-Catafau L, Prats N, Xaus C, Gelpi E, Peralta C. (2002). Ischemic preconditioning increases the tolerance of fatty liver to hepatic ischemia-reperfusion injury in the rat. Am J Pathol 161: 587-601
37. Shiraishi K, Matsuzaki S, Ishida H, Nakazawa H. (1993). Impaired erythrocyte deformability and membrane fluidity in alcoholic liver disease: participation in disturbed hepatic microcirculation. Alcohol Alcohol Suppl 1A:59-64
38. Sindram D, Porte RJ, Hoffman MR, Bentley RC, Clavien PA. (2000). Platelets induce sinusoidal endothelial cell apoptosis upon reperfusion of the cold ischemic rat liver. Gastroenterology 118:183-191
39. Stryer L. (1995). Biochemistry. 4th edition. New York: W.H. Freeman & Company
40. Suematsu M, Wakabayashi Y, Ishimura Y. (1996). Gaseous monoxides: a new class of microvascular regulator in the liver. Cardiovasc Res 32:679-686
41. Sun CK, Zhang XY, Zimmermann A, Davis G, Wheatley AM. (2001). Effect of ischemia-reperfusion injury on the microcirculation of the steatotic liver of the Zucker rat. Transplantation 72:1625-1631
42. Takeda Y, Arii S, Kaido T, Niwano M, Moriga T, Mori A, Hanaki K, Gorrin-Rivas MJ, Ishii T, Sato M, Imamura M. (1999). Morphologic alteration of hepatocytes and sinuisoidal endothelial cells in rat fatty liver during cold preservation and the protective effect of hepatocyte growth factor. Transplantation 67: 820-828
43. Taneja C, Prescott L, Koneru B. (1998). Critical preservation injury in rat fatty liver is to hepatocytes, not sinusoidal lining cells. Transplantation 65:167-172
44. Terajima H, Enders G, Thiaener A, Hammer C, Kondo T, Thiery J, Yamamoto Y, Yamaoka Y, Messmer K. (2000). Impact of hyperthermic preconditioning on postischemic hepatic microcirculatory disturbances in an isolated perfusion model of the rat liver. Hepatology 31:407-415
45. Teramoto K, Bowers JL, Kruskal JB, Clouse ME. (1993). Hepatic microcirculatory changes after reperfusion in fatty and normal liver transplantation in the rat. Transplantation 56:1076-1082
46. Underwood Ground KE. (1984). Prevalence of fatty liver in healthy male adults accidentally killed. Aviat Space Environ Med 55:59-61
47. Villeneuve JP, Dagenais M, Huet PM, Roy A, Lapointe R, Marleau D. (1996). The hepatic microcirculation in the isolated perfused human liver. Hepatology 23:24-31
48. Vollmar B, Glasz J, Leiderer R, Post S, Menger MD. (1994). Hepatic microcirculatory perfusion failure is a determinant of liver dysfunction in warm ischemia-reperfusion. Am J Pathol 145:1421-1431
49. Wake K. (1999). Cell-cell organization and functions of 'sinusoids' in liver microcirculation system. J Electron Microsc (Tokyo) 48(2):89-98
50. Yadav SS, Howell DN, Steeber DA, Harland RC, Tedder TF, Clavien PA. (1999). P-Selectin mediates reperfusion injury through neutrophil and platelet sequestration in the warm ischemic mouse liver. Hepatology 29:1494-1502
51. Youssef W, McCullough AJ. (2002). Diabetes mellitus, obesity, and hepatic steatosis. Semin Gastrointest Dis 13:17-30
52. Zhong Z, Arteel GE, Connor HD, Schemmer P, Chou SC, Raleigh JA, Mason RP, Lemasters JJ, Thurman RG. (1999). Binge drinking disturbs hepatic microcirculation after transplantation: prevention with free radical scavengers. J Pharmacol Exp Ther 290:611-620
53. Zhong Z, Connor H, Mason RP, Qu W, Stachlewitz RF, Gao W, Lemasters JJ, Thurman RG. (1996). Destruction of Kupffer cells increases survival and reduces graft injury after transplantation of fatty livers from ethanol-treated rats. Liver Transpl Surg 2:383-387