-
1
-
-
0001471024
-
Human leukocytic pyrogen: Purification and development of a radioimmunoassay
-
Dinarello CA, Renfer L, Wolff SM. (1977) Human leukocytic pyrogen: purification and development of a radioimmunoassay. Proc. Natl. Acad. Sci. U. S. A. 74:4624–7.
-
(1977)
Proc. Natl. Acad. Sci. U. S. A
, vol.74
, pp. 4624-4627
-
-
Dinarello, C.A.1
Renfer, L.2
Wolff, S.M.3
-
3
-
-
0000072070
-
Lipoprotein lipase suppression in 3T3-L1 cells by an endotoxin-induced mediator from exudate cells
-
Kawakami M, Pekala PH, Lane MD, Cerami A. (1982) Lipoprotein lipase suppression in 3T3-L1 cells by an endotoxin-induced mediator from exudate cells. Proc. Natl. Acad. Sci. U. S. A. 79:912–6.
-
(1982)
Proc. Natl. Acad. Sci. U. S. A
, vol.79
, pp. 912-916
-
-
Kawakami, M.1
Pekala, P.H.2
Lane, M.D.3
Cerami, A.4
-
4
-
-
0022472749
-
Tumor necrosis factor (Cachectin) is an endogenous pyrogen and induces production of interleukin 1
-
Dinarello CA, et al. (1986) Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. J. Exp. Med. 163:1433–50.
-
(1986)
J. Exp. Med
, vol.163
, pp. 1433-1450
-
-
Dinarello, C.A.1
-
5
-
-
0021684992
-
Interleukin-1 and the pathogenesis of the acute-phase response
-
Dinarello CA. (1984) Interleukin-1 and the pathogenesis of the acute-phase response. N. Engl. J. Med. 311:1413–8.
-
(1984)
N. Engl. J. Med
, vol.311
, pp. 1413-1418
-
-
Dinarello, C.A.1
-
6
-
-
0024314554
-
Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis
-
Brennan FM, Chantry D, Jackson A, Maini R, Feldmann M. (1989) Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis. Lancet. 2:244–7.
-
(1989)
Lancet
, vol.2
, pp. 244-247
-
-
Brennan, F.M.1
Chantry, D.2
Jackson, A.3
Maini, R.4
Feldmann, M.5
-
7
-
-
0023773031
-
Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: Prolonged production of IL-1 alpha. Clin. Exp
-
Buchan G, et al. (1988) Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 alpha. Clin. Exp. Immunol. 73:449–55.
-
(1988)
Immunol
, vol.73
, pp. 449-455
-
-
Buchan, G.1
-
8
-
-
0022296893
-
Cachectin/ tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts
-
Dayer JM, Beutler B, Cerami A. (1985) Cachectin/ tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts. J. Exp. Med. 162:2163–8.
-
(1985)
J. Exp. Med
, vol.162
, pp. 2163-2168
-
-
Dayer, J.M.1
Beutler, B.2
Cerami, A.3
-
9
-
-
0022441214
-
Tumour necrosis factor alpha stimulates resorption and inhibits synthesis of proteoglycan in cartilage
-
Saklatvala J. (1986) Tumour necrosis factor alpha stimulates resorption and inhibits synthesis of proteoglycan in cartilage. Nature. 322:547–9.
-
(1986)
Nature
, vol.322
, pp. 547-549
-
-
Saklatvala, J.1
-
10
-
-
78650185999
-
The value of failure: The discovery of TNF and its natural inhibitor erythropoietin
-
Cerami A. (2011) The value of failure: the discovery of TNF and its natural inhibitor erythropoietin. J. Intern. Med. 269:8–15.
-
(2011)
J. Intern. Med
, vol.269
, pp. 8-15
-
-
Cerami, A.1
-
11
-
-
80052189130
-
Efficacy and safety of the human anti-IL-1beta monoclonal antibody canakinumab in rheumatoid arthritis: Results of a 12-week, phase II, dose-finding study. BMC Musculoskelet
-
Alten R, et al. (2011) Efficacy and safety of the human anti-IL-1beta monoclonal antibody canakinumab in rheumatoid arthritis: results of a 12-week, phase II, dose-finding study. BMC Musculoskelet. Disord. 12:153.
-
(2011)
Disord
, vol.12
, pp. 153
-
-
Alten, R.1
-
12
-
-
84893646090
-
Interleukin-1 blockade in rheumatoid arthritis and heart failure: A missed opportunity
-
Abbate A, Canada JM, Van Tassell BW, Wise CM, Dinarello CA. (2014) Interleukin-1 blockade in rheumatoid arthritis and heart failure: a missed opportunity? Int. J. Cardiol. 171:e125–6.
-
(2014)
Int. J. Cardiol
, vol.171
-
-
Abbate, A.1
Canada, J.M.2
Van Tassell, B.W.3
Wise, C.M.4
Dinarello, C.A.5
-
13
-
-
84858405983
-
Enhanced interleukin-1 activity contributes to exercise intolerance in patients with systolic heart failure
-
Van Tassell BW, et al. (2012) Enhanced interleukin-1 activity contributes to exercise intolerance in patients with systolic heart failure. PLoS One. 7:e33438.
-
(2012)
Plos One
, pp. 7
-
-
Van Tassell, B.W.1
-
14
-
-
77957688721
-
Canakinumab for the treatment of acute flares in difficult-to-treat gouty arthritis: Results of a multicenter, phase II, dose-ranging study
-
So A, et al. (2010) Canakinumab for the treatment of acute flares in difficult-to-treat gouty arthritis: results of a multicenter, phase II, dose-ranging study. Arthritis Rheum. 62:3064–76.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 3064-3076
-
-
So, A.1
-
15
-
-
34047174085
-
A pilot study of IL-1 inhibition by anakinra in acute gout. Arthritis Res
-
So A, De Smedt T, Revaz S, Tschopp J. (2007) A pilot study of IL-1 inhibition by anakinra in acute gout. Arthritis Res. Ther. 9:28.
-
(2007)
Ther
, vol.9
, pp. 28
-
-
So, A.1
De Smedt, T.2
Revaz, S.3
Tschopp, J.4
-
16
-
-
79957646006
-
Canakinumab reduces the risk of acute gouty arthritis flares during initiation of allopurinol treatment: Results of a double- blind, randomised study
-
Schlesinger N, et al. (2011) Canakinumab reduces the risk of acute gouty arthritis flares during initiation of allopurinol treatment: results of a double- blind, randomised study. Ann. Rheum. Dis. 70:1264–71.
-
(2011)
Ann. Rheum. Dis
, vol.70
, pp. 1264-1271
-
-
Schlesinger, N.1
-
17
-
-
70349402166
-
The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: Results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study
-
Terkeltaub R, et al. (2009) The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study. Ann. Rheum. Dis. 68:1613–7.
-
(2009)
Ann. Rheum. Dis
, vol.68
, pp. 1613-1617
-
-
Terkeltaub, R.1
-
18
-
-
84899989426
-
MABp1, a first-in-class true human antibody targeting interleukin-1alpha in refractory cancers: An open-label, phase 1 doseescalation and expansion study
-
Hong DS, et al. (2014) MABp1, a first-in-class true human antibody targeting interleukin-1alpha in refractory cancers: an open-label, phase 1 doseescalation and expansion study. Lancet Oncol. 15:656–66.
-
(2014)
Lancet Oncol
, vol.15
, pp. 656-666
-
-
Hong, D.S.1
-
19
-
-
64049084303
-
Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages
-
Netea MG, et al. (2009) Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages. Blood. 113:2324–35.
-
(2009)
Blood
, vol.113
, pp. 2324-2335
-
-
Netea, M.G.1
-
20
-
-
77949889567
-
Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta
-
Okamoto M, et al. (2009) Constitutively active inflammasome in human melanoma cells mediating autoinflammation via caspase-1 processing and secretion of interleukin-1beta. J. Biol. Chem. 285:6477–88.
-
(2009)
J. Biol. Chem
, vol.285
, pp. 6477-6488
-
-
Okamoto, M.1
-
21
-
-
84874249068
-
NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1beta processing via the NLRP1 inflammasome
-
Levandowski CB, et al. (2013) NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1beta processing via the NLRP1 inflammasome. Proc. Natl. Acad. Sci. U. S. A. 110:2952–6.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A
, vol.110
, pp. 2952-2956
-
-
Levandowski, C.B.1
-
22
-
-
18644385243
-
Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade
-
Pascual V, Allantaz F, Arce E, Punaro M, Banchereau J. (2005) Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade. J. Exp. Med. 201:1479–86.
-
(2005)
J. Exp. Med
, vol.201
, pp. 1479-1486
-
-
Pascual, V.1
Allantaz, F.2
Arce, E.3
Punaro, M.4
Banchereau, J.5
-
23
-
-
33746876396
-
Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition
-
Goldbach-Mansky R, et al. (2006) Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition. N. Engl. J. Med. 355:581–92.
-
(2006)
N. Engl. J. Med
, vol.355
, pp. 581-592
-
-
Goldbach-Mansky, R.1
-
24
-
-
66049094734
-
In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes
-
Lachmann HJ, et al. (2009) In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes. J. Exp. Med. 206:1029–36.
-
(2009)
J. Exp. Med
, vol.206
, pp. 1029-1036
-
-
Lachmann, H.J.1
-
25
-
-
0033008274
-
MEFV mutation analysis in patients suffering from amyloidosis of familial Mediterranean fever
-
Livneh A, et al. (1999) MEFV mutation analysis in patients suffering from amyloidosis of familial Mediterranean fever. Amyloid. 6:1–6.
-
(1999)
Amyloid
, vol.6
, pp. 1-6
-
-
Livneh, A.1
-
26
-
-
0037349294
-
Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis. Mol
-
Chae JJ, et al. (2003) Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis. Mol. Cell. 11:591–604.
-
(2003)
Cell
, vol.11
, pp. 591-604
-
-
Chae, J.J.1
-
27
-
-
0035179970
-
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat
-
Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD. (2001) Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat. Genet. 29:301–5.
-
(2001)
Genet
, vol.29
, pp. 301-305
-
-
Hoffman, H.M.1
Mueller, J.L.2
Broide, D.H.3
Wanderer, A.A.4
Kolodner, R.D.5
-
28
-
-
0036899758
-
De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatalonset multisystem inflammatory disease (NOMID): A new member of the expanding family of pyrin-associated autoinflammatory diseases
-
Aksentijevich I, et al. (2002) De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatalonset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases. Arthritis Rheum. 46:3340–8.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 3340-3348
-
-
Aksentijevich, I.1
-
29
-
-
33645119818
-
Beneficial response to anakinra and thalidomide in Schnitzler’s syndrome
-
de Koning HD, et al. (2006) Beneficial response to anakinra and thalidomide in Schnitzler’s syndrome. Ann. Rheum. Dis. 65:542–4.
-
(2006)
Ann. Rheum. Dis
, vol.65
, pp. 542-544
-
-
De Koning, H.D.1
-
30
-
-
34848875155
-
Pattern of interleukin- 1beta secretion in response to lipopolysaccharide and ATP before and after interleukin-1 blockade in patients with CIAS1 mutations
-
Gattorno M, et al. (2007) Pattern of interleukin- 1beta secretion in response to lipopolysaccharide and ATP before and after interleukin-1 blockade in patients with CIAS1 mutations. Arthritis Rheum. 56:3138–48.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3138-3148
-
-
Gattorno, M.1
-
31
-
-
0035808396
-
Altered cytokine production in mice lacking P2X(7) receptors
-
Solle M, et al. (2001) Altered cytokine production in mice lacking P2X(7) receptors. J. Biol. Chem. 276:125–32.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 125-132
-
-
Solle, M.1
-
32
-
-
3042800587
-
Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes
-
Andrei C, et al. (2004) Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes. Proc. Natl. Acad. Sci. U. S. A. 101:9745–50.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A
, vol.101
, pp. 9745-9750
-
-
Andrei, C.1
-
33
-
-
79953323633
-
A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin- 1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic arthritis (ANAJIS trial)
-
Quartier P, et al. (2011) A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin- 1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic arthritis (ANAJIS trial). Ann. Rheum. Dis. 70:747–54.
-
(2011)
Ann. Rheum. Dis
, vol.70
, pp. 747-754
-
-
Quartier, P.1
-
34
-
-
84871321221
-
Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis
-
Ruperto N, et al. (2012) Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis. N. Engl. J. Med. 367:2396–406.
-
(2012)
N. Engl. J. Med
, vol.367
, pp. 2396-2406
-
-
Ruperto, N.1
-
35
-
-
84856370186
-
A phase II, multicenter, open-label study evaluating dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features
-
Ruperto N, et al. (2012) A phase II, multicenter, open-label study evaluating dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features. Arthritis Rheum. 64:557–67.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 557-567
-
-
Ruperto, N.1
-
36
-
-
18644370644
-
Rapid responses to anakinra in patients with refractory adult-onset Still’s disease
-
Fitzgerald AA, Leclercq SA, Yan A, Homik JE, Dinarello CA. (2005) Rapid responses to anakinra in patients with refractory adult-onset Still’s disease. Arthritis Rheum. 52:1794–803.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1794-1803
-
-
Fitzgerald, A.A.1
Leclercq, S.A.2
Yan, A.3
Homik, J.E.4
Dinarello, C.A.5
-
37
-
-
34249799278
-
Anakinra treatment in patients with adult-onset Still’s disease is fast, effective, safe and steroid sparing: Experience from an uncontrolled trial
-
Kalliolias GD, Georgiou PE, Antonopoulos IA, Andonopoulos AP, Liossis SN. (2007) Anakinra treatment in patients with adult-onset Still’s disease is fast, effective, safe and steroid sparing: experience from an uncontrolled trial. Ann. Rheum. Dis. 66:842–3.
-
(2007)
Ann. Rheum. Dis
, vol.66
, pp. 842-843
-
-
Kalliolias, G.D.1
Georgiou, P.E.2
Antonopoulos, I.A.3
Onopoulos, A.P.4
Liossis, S.N.5
-
38
-
-
79958819509
-
Efficacy and long-term follow-up of IL-1R inhibitor anakinra in adults with Still’s disease: A case-series study. Arthritis Res
-
Laskari K, Tzioufas AG, Moutsopoulos HM. (2011) Efficacy and long-term follow-up of IL-1R inhibitor anakinra in adults with Still’s disease: a case-series study. Arthritis Res. Ther. 13:91.
-
(2011)
Ther
, vol.13
, pp. 91
-
-
Laskari, K.1
Tzioufas, A.G.2
Moutsopoulos, H.M.3
-
39
-
-
84874909878
-
Adult-onset Still’s disease: Clinical, serological and therapeutic considerations. Clin. Exp
-
Iliou C, Papagoras C, Tsifetaki N, Voulgari PV, Drosos AA. (2013) Adult-onset Still’s disease: clinical, serological and therapeutic considerations. Clin. Exp. Rheumatol. 31:47–52.
-
(2013)
Rheumatol
, vol.31
, pp. 47-52
-
-
Iliou, C.1
Papagoras, C.2
Tsifetaki, N.3
Voulgari, P.V.4
Drosos, A.A.5
-
40
-
-
82555192469
-
Successful canakinumab treatment identifies IL-1beta as a pivotal mediator in Schnitzler syndrome
-
de Koning HD, Schalkwijk J, van der Meer JW, Simon A. (2011) Successful canakinumab treatment identifies IL-1beta as a pivotal mediator in Schnitzler syndrome. J. Allergy Clin. Immunol. 128:1352–4.
-
(2011)
J. Allergy Clin. Immunol
, vol.128
, pp. 1352-1354
-
-
De Koning, H.D.1
Schalkwijk, J.2
Van Der Meer, J.W.3
Simon, A.4
-
41
-
-
84883790466
-
Sustained efficacy of the monoclonal anti-interleukin-1 beta antibody canakinumab in a 9-month trial in Schnitzler’s syndrome
-
de Koning HD, et al. (2013) Sustained efficacy of the monoclonal anti-interleukin-1 beta antibody canakinumab in a 9-month trial in Schnitzler’s syndrome. Ann. Rheum. Dis. 72:1634–8.
-
(2013)
Ann. Rheum. Dis
, vol.72
, pp. 1634-1638
-
-
De Koning, H.D.1
-
42
-
-
84973412335
-
Successful treatment of Schnitzler syndrome with canakinumab
-
Pesek R, Fox R. (2014) Successful treatment of Schnitzler syndrome with canakinumab. Cutis. 94:E11–12.
-
(2014)
Cutis
, vol.94
-
-
Pesek, R.1
Fox, R.2
-
43
-
-
80052199830
-
Schnitzler syndrome: Diagnostics and treatment. Klin
-
Szturz P, et al. (2011) Schnitzler syndrome: diagnostics and treatment. Klin. Onkol. 24:271–7.
-
(2011)
Onkol
, vol.24
, pp. 271-277
-
-
Szturz, P.1
-
44
-
-
84873703941
-
Canakinumab in Schnitzler syndrome. Semin
-
Vanderschueren S, Knockaert D. (2013) Canakinumab in Schnitzler syndrome. Semin. Arthritis Rheum. 42:413–6.
-
(2013)
Arthritis Rheum
, vol.42
, pp. 413-416
-
-
Vanderschueren, S.1
Knockaert, D.2
-
45
-
-
61449122079
-
Induction of a chronic disease state in patients with smoldering or indolent multiple myeloma by targeting interleukin 1β-induced interleukin 6 production and the myeloma proliferative component. Mayo Clin
-
Lust JA, et al. (2009) Induction of a chronic disease state in patients with smoldering or indolent multiple myeloma by targeting interleukin 1β-induced interleukin 6 production and the myeloma proliferative component. Mayo Clin. Proc. 84:114–22.
-
(2009)
Proc
, vol.84
, pp. 114-122
-
-
Lust, J.A.1
-
46
-
-
78651365935
-
Rapid and sustained remission of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome through treatment with anakinra and corticosteroids
-
Bruck N, et al. (2011) Rapid and sustained remission of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome through treatment with anakinra and corticosteroids. J. Clin. Rheumatol. 17:23–7.
-
(2011)
J. Clin. Rheumatol
, vol.17
, pp. 23-27
-
-
Bruck, N.1
-
48
-
-
84876923109
-
Higher-dose Anakinra is effective in a case of medically refractory macrophage activation syndrome
-
Kahn PJ, Cron RQ. (2013) Higher-dose Anakinra is effective in a case of medically refractory macrophage activation syndrome. J. Rheumatol. 40:743–4.
-
(2013)
J. Rheumatol
, vol.40
, pp. 743-744
-
-
Kahn, P.J.1
Cron, R.Q.2
-
49
-
-
59149104561
-
A case of macrophage activation syndrome successfully treated with anakinra
-
Kelly A, Ramanan AV. (2008) A case of macrophage activation syndrome successfully treated with anakinra. Nat. Clin. Pract. Rheumatol. 4:615–20.
-
(2008)
Nat. Clin. Pract. Rheumatol
, vol.4
, pp. 615-620
-
-
Kelly, A.1
Ramanan, A.V.2
-
51
-
-
84902181337
-
Plasma exchange, methylprednisolone, IV immune globulin, and now anakinra support continued PICU equipoise in management of hyperferritinemia- associated sepsis/multiple organ dysfunction syndrome/macrophage activation syndrome/ secondary hemophagocytic lymphohistiocytosis syndrome. Pediatr. Crit
-
Simon DW, Aneja R, Carcillo JA, Halstead ES. (2014) Plasma exchange, methylprednisolone, IV immune globulin, and now anakinra support continued PICU equipoise in management of hyperferritinemia- associated sepsis/multiple organ dysfunction syndrome/macrophage activation syndrome/ secondary hemophagocytic lymphohistiocytosis syndrome. Pediatr. Crit. Care Med. 15:486–8.
-
(2014)
Care Med
, vol.15
, pp. 486-488
-
-
Simon, D.W.1
Aneja, R.2
Carcillo, J.A.3
Halstead, E.S.4
-
52
-
-
84921412381
-
Pathogenesis of macrophage activation syndrome and potential for cytokine-directed therapies
-
[Epub ahead of print]
-
Schulert GS, Grom AA. (2014) Pathogenesis of macrophage activation syndrome and potential for cytokine-directed therapies. Annu. Rev. Med. 2014, Nov 5 [Epub ahead of print].
-
(2014)
Annu. Rev. Med. 2014, Nov
, vol.5
-
-
Schulert, G.S.1
Grom, A.A.2
-
53
-
-
84899757917
-
Urticaria, fever, and hypofibrinogenemia
-
Mohr V, et al. (2014) Urticaria, fever, and hypofibrinogenemia. Arthritis Rheumatol. 66:1377.
-
(2014)
Arthritis Rheumatol
, vol.66
, pp. 1377
-
-
Mohr, V.1
-
54
-
-
84922588116
-
Refractory macrophage activation syndrome in a patient with SLE and APLA syndrome – successful use of PETCT and Anakinra in its diagnosis and treatment. Mod. Rheumatol. 2013
-
[Epub ahead of print]
-
Tayer-Shifman OE, Ben-Chetrit E. (2013) Refractory macrophage activation syndrome in a patient with SLE and APLA syndrome – successful use of PETCT and Anakinra in its diagnosis and treatment. Mod. Rheumatol. 2013, Oct 21 [Epub ahead of print].
-
(2013)
Oct
, vol.21
-
-
Tayer-Shifman, O.E.1
Ben-Chetrit, E.2
-
55
-
-
84861685616
-
Macrophage activation syndrome as part of systemic juvenile idiopathic arthritis: Diagnosis, genetics, pathophysiology and treatment
-
Ravelli A, Grom AA, Behrens EM, Cron RQ. (2012) Macrophage activation syndrome as part of systemic juvenile idiopathic arthritis: diagnosis, genetics, pathophysiology and treatment. Genes Immun. 13:289–98.
-
(2012)
Genes Immun
, vol.13
, pp. 289-298
-
-
Ravelli, A.1
Grom, A.A.2
Behrens, E.M.3
Cron, R.Q.4
-
56
-
-
0030877935
-
Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: A phase III, randomized, double-blind, placebo-controlled, multicenter trial: The Interleukin-1 Receptor Antagonist Sepsis Investigator Group. Crit
-
Opal SM, et al. (1997) Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial: the Interleukin-1 Receptor Antagonist Sepsis Investigator Group. Crit. Care Med. 25:1115–24.
-
(1997)
Care Med
, vol.25
, pp. 1115-1124
-
-
Opal, S.M.1
-
57
-
-
70350168010
-
IL-1 inhibition with anakinra in a patient with refractory gout
-
Singh D, Huston KK. (2009) IL-1 inhibition with anakinra in a patient with refractory gout. J. Clin. Rheumatol. 15:366.
-
(2009)
J. Clin. Rheumatol
, vol.15
, pp. 366
-
-
Singh, D.1
Huston, K.K.2
-
58
-
-
69749116766
-
Case of anakinra as a steroid-sparing agent for gout inflammation
-
Gratton SB, Scalapino KJ, Fye KH. (2009) Case of anakinra as a steroid-sparing agent for gout inflammation. Arthritis Rheum. 61:1268–70.
-
(2009)
Arthritis Rheum
, vol.61
, pp. 1268-1270
-
-
Gratton, S.B.1
Scalapino, K.J.2
Fye, K.H.3
-
59
-
-
84881334136
-
Treatment of acute gouty arthritis in complex hospitalized patients with anakinra
-
Ghosh P, Cho M, Rawat G, Simkin PA, Gardner GC. (2013) Treatment of acute gouty arthritis in complex hospitalized patients with anakinra. Arthritis Care Res. 65:1381–4.
-
(2013)
Arthritis Care Res
, vol.65
, pp. 1381-1384
-
-
Ghosh, P.1
Cho, M.2
Rawat, G.3
Simkin, P.A.4
Gardner, G.C.5
-
60
-
-
84864335117
-
Rilonacept (Interleukin- 1 trap) for prevention of gout flares during initiation of uric acid-lowering therapy: Results from a phase III randomized, double-blind, placebo-controlled, confirmatory efficacy study
-
Schumacher HR Jr, et al. (2012) Rilonacept (interleukin- 1 trap) for prevention of gout flares during initiation of uric acid-lowering therapy: results from a phase III randomized, double-blind, placebo-controlled, confirmatory efficacy study. Arthritis Care Res. 64:1462–70.
-
(2012)
Arthritis Care Res
, vol.64
, pp. 1462-1470
-
-
Schumacher, H.R.1
-
61
-
-
84874162590
-
Mechanistic aspects of inflammation and clinical management of inflammation in acute gouty arthritis
-
Cronstein BN, Sunkureddi P. (2013) Mechanistic aspects of inflammation and clinical management of inflammation in acute gouty arthritis. J. Clin. Rheumatol. 19:19–29.
-
(2013)
J. Clin. Rheumatol
, vol.19
, pp. 19-29
-
-
Cronstein, B.N.1
Sunkureddi, P.2
-
62
-
-
58749083861
-
Crystals of monosodium urate monohydrate enhance lipopolysaccharide-induced release of interleukin 1 beta by mononuclear cells through a caspase 1- mediated process
-
Giamarellos-Bourboulis EJ, et al. (2009) Crystals of monosodium urate monohydrate enhance lipopolysaccharide-induced release of interleukin 1 beta by mononuclear cells through a caspase 1- mediated process. Ann. Rheum. Dis. 68:273–8.
-
(2009)
Ann. Rheum. Dis
, vol.68
, pp. 273-278
-
-
Giamarellos-Bourboulis, E.J.1
-
63
-
-
78249286865
-
Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1beta production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis
-
Joosten LA, et al. (2010) Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1beta production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis. Arthritis Rheum. 62:3237–48.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 3237-3248
-
-
Joosten, L.A.1
-
64
-
-
0020909363
-
The fever of gout: Urate crystals activate endogenous pyrogen production from human and rabbit mononuclear phagocytes
-
Duff GW, Atkins E, Malawista SE. (1983) The fever of gout: urate crystals activate endogenous pyrogen production from human and rabbit mononuclear phagocytes. Trans. Assoc. Am. Physicians. 96:234–45.
-
(1983)
Trans. Assoc. Am. Physicians
, vol.96
, pp. 234-245
-
-
Duff, G.W.1
Atkins, E.2
Malawista, S.E.3
-
65
-
-
34548667797
-
Management of treatment resistant inflammation of acute on chronic tophaceous gout with anakinra
-
McGonagle D, et al. (2007) Management of treatment resistant inflammation of acute on chronic tophaceous gout with anakinra. Ann. Rheum. Dis. 66:1683–4.
-
(2007)
Ann. Rheum. Dis
, vol.66
, pp. 1683-1684
-
-
Mc gonagle, D.1
-
66
-
-
39749175570
-
Successful treatment of resistant pseudogout with anakinra
-
McGonagle D, Tan AL, Madden J, Emery P, McDermott MF. (2008) Successful treatment of resistant pseudogout with anakinra. Arthritis Rheum. 58:631–3.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 631-633
-
-
Mc gonagle, D.1
Tan, A.L.2
Madden, J.3
Emery, P.4
Mc dermott, M.F.5
-
67
-
-
75149194057
-
Update on gout: New therapeutic strategies and options. Nat
-
Terkeltaub R. (2010) Update on gout: new therapeutic strategies and options. Nat. Rev. Rheumatol. 6:30–8.
-
(2010)
Rev. Rheumatol
, vol.6
, pp. 30-38
-
-
Terkeltaub, R.1
-
68
-
-
67649798632
-
Anakinra is a possible alternative in the treatment and prevention of acute attacks of pseudogout in end-stage renal failure
-
Announ N, Palmer G, Guerne PA, Gabay C. (2009) Anakinra is a possible alternative in the treatment and prevention of acute attacks of pseudogout in end-stage renal failure. Joint Bone Spine. 76:424–6.
-
(2009)
Joint Bone Spine
, vol.76
, pp. 424-426
-
-
Announ, N.1
Palmer, G.2
Guerne, P.A.3
Gabay, C.4
-
69
-
-
84867405545
-
Canakinumab for acute gouty arthritis in patients with limited treatment options: Results from two randomised, multicentre, active-controlled, double-blind trials and their initial extensions
-
Schlesinger N, et al. (2012) Canakinumab for acute gouty arthritis in patients with limited treatment options: results from two randomised, multicentre, active-controlled, double-blind trials and their initial extensions. Ann. Rheum. Dis. 71:1839–48.
-
(2012)
Ann. Rheum. Dis
, vol.71
, pp. 1839-1848
-
-
Schlesinger, N.1
-
70
-
-
73249144903
-
Inflammatory arthritis in caspase 1 gene-deficient mice:Contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta
-
Joosten LA, et al. (2009) Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta. Arthritis Rheum. 60:3651–62.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 3651-3662
-
-
Joosten, L.A.1
-
71
-
-
67449124615
-
Erosive osteoarthritis of the hand: Clinical experience with anakinra
-
Bacconnier L, Jorgensen C, Fabre S. (2009) Erosive osteoarthritis of the hand: clinical experience with anakinra. Ann. Rheum. Dis. 68:1078–9.
-
(2009)
Ann. Rheum. Dis
, vol.68
, pp. 1078-1079
-
-
Bacconnier, L.1
Jorgensen, C.2
Fabre, S.3
-
72
-
-
22244474585
-
Safety study of intraarticular injection of interleukin 1 receptor antagonist in patients with painful knee osteoarthritis: A multicenter study
-
Chevalier X, et al. (2005) Safety study of intraarticular injection of interleukin 1 receptor antagonist in patients with painful knee osteoarthritis: a multicenter study. J. Rheumatol. 32:1317–23.
-
(2005)
J. Rheumatol
, vol.32
, pp. 1317-1323
-
-
Chevalier, X.1
-
73
-
-
62549104691
-
Intraarticular injection of anakinra in osteoarthritis of the knee: A multicenter, randomized, double-blind, placebocontrolled study
-
Chevalier X, et al. (2009) Intraarticular injection of anakinra in osteoarthritis of the knee: a multicenter, randomized, double-blind, placebocontrolled study. Arthritis Rheum. 61:344–52.
-
(2009)
Arthritis Rheum
, vol.61
, pp. 344-352
-
-
Chevalier, X.1
-
74
-
-
79960862976
-
A randomized, double-blind study of AMG 108 (A fully human monoclonal antibody to IL 1R1) in patients with osteoarthritis of the knee. Arthritis Res
-
Cohen SB, et al. (2011) A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL 1R1) in patients with osteoarthritis of the knee. Arthritis Res. Ther. 13:125.
-
(2011)
Ther
, vol.13
, pp. 125
-
-
Cohen, S.B.1
-
75
-
-
0036738398
-
Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets
-
Maedler K, et al. (2002) Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets. J. Clin. Invest. 110:851–60.
-
(2002)
J. Clin. Invest
, vol.110
, pp. 851-860
-
-
Maedler, K.1
-
76
-
-
79151478555
-
Type 2 diabetes as an inflammatory disease. Nat
-
Donath MY, Shoelson SE. (2011) Type 2 diabetes as an inflammatory disease. Nat. Rev. Immunol. 11:98–107.
-
(2011)
Rev. Immunol
, vol.11
, pp. 98-107
-
-
Donath, M.Y.1
Shoelson, S.E.2
-
77
-
-
77956958947
-
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes. Nat
-
Masters SL, et al. (2010) Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes. Nat. Immunol. 11:897–904.
-
(2010)
Immunol
, vol.11
, pp. 897-904
-
-
Masters, S.L.1
-
78
-
-
79960086288
-
Treatment with anakinra improves disposition index but not insulin sensitivity in nondiabetic subjects with the metabolic syndrome: A randomized, double-blind, placebo-controlled study
-
van Asseldonk EJ, et al. (2011) Treatment with anakinra improves disposition index but not insulin sensitivity in nondiabetic subjects with the metabolic syndrome: a randomized, double-blind, placebo-controlled study. J. Clin. Endocrinol. Metab 96:2119–26.
-
(2011)
J. Clin. Endocrinol. Metab
, vol.96
, pp. 2119-2126
-
-
Van Asseldonk, E.J.1
-
79
-
-
34247170807
-
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
-
Larsen CM, et al. (2007) Interleukin-1-receptor antagonist in type 2 diabetes mellitus. N. Engl. J. Med. 356:1517–26.
-
(2007)
N. Engl. J. Med
, vol.356
, pp. 1517-1526
-
-
Larsen, C.M.1
-
80
-
-
69549105888
-
Sustained effects of interleukin- 1 receptor antagonist treatment in type 2 diabetes
-
Larsen CM, et al. (2009) Sustained effects of interleukin- 1 receptor antagonist treatment in type 2 diabetes. Diabetes Care. 32:1663–8.
-
(2009)
Diabetes Care
, vol.32
, pp. 1663-1668
-
-
Larsen, C.M.1
-
81
-
-
84864386088
-
Effects of gevokizumab on glycemia and inflammatory markers in type 2 diabetes
-
Cavelti-Weder C, et al. (2012) Effects of gevokizumab on glycemia and inflammatory markers in type 2 diabetes. Diabetes Care. 35:1654–62.
-
(2012)
Diabetes Care
, vol.35
, pp. 1654-1662
-
-
Cavelti-Weder, C.1
-
82
-
-
84892862293
-
IL-1beta antibody (Canakinumab) improves insulin secretion rates in subjects with impaired glucose tolerance and type 2 diabetes
-
Rissanen A, Howard C, Botha J, Thuren T. (2011) IL-1beta antibody (canakinumab) improves insulin secretion rates in subjects with impaired glucose tolerance and type 2 diabetes. Diabetes. 60 Suppl 1.
-
(2011)
Diabetes
, vol.60
, Issue.1
, pp. 1
-
-
Rissanen, A.1
Howard, C.2
Botha, J.3
Thuren, T.4
-
83
-
-
84878774925
-
Double-blind, randomized study evaluating the glycemic and antiinflammatory effects of subcutaneous LY2189102, a neutralizing IL-1beta antibody, in patients with type 2 diabetes
-
Sloan-Lancaster J, et al. (2013) Double-blind, randomized study evaluating the glycemic and antiinflammatory effects of subcutaneous LY2189102, a neutralizing IL-1beta antibody, in patients with type 2 diabetes. Diabetes Care. 36:2239–46.
-
(2013)
Diabetes Care
, vol.36
, pp. 2239-2246
-
-
Sloan-Lancaster, J.1
-
84
-
-
84860805156
-
Inhibition of IL- 1beta improves fatigue in type 2 diabetes
-
Cavelti-Weder C, et al. (2011) Inhibition of IL- 1beta improves fatigue in type 2 diabetes. Diabetes Care. 34:e158s.
-
(2011)
Diabetes Care
, vol.34
-
-
Cavelti-Weder, C.1
-
85
-
-
84855568775
-
Interleukin-1 inhibition and fatigue in primary Sjogren’s syndrome: A double blind, randomised clinical trial
-
Norheim KB, Harboe E, Goransson LG, Omdal R. (2012) Interleukin-1 inhibition and fatigue in primary Sjogren’s syndrome: a double blind, randomised clinical trial. PLoS One. 7:e30123.
-
(2012)
Plos One
, pp. 7
-
-
Norheim, K.B.1
Harboe, E.2
Goransson, L.G.3
Omdal, R.4
-
86
-
-
78649498271
-
The inflammasomemediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity. Cell
-
Stienstra R, et al. (2011) The inflammasomemediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity. Cell. Metab. 12:593–605.
-
(2011)
Metab
, vol.12
, pp. 593-605
-
-
Stienstra, R.1
-
87
-
-
35248883867
-
Differential role and tissue specificity of interleukin-1alpha gene expression in atherogenesis and lipid metabolism
-
Kamari Y, et al. (2007) Differential role and tissue specificity of interleukin-1alpha gene expression in atherogenesis and lipid metabolism. Atherosclerosis. 195:31–8.
-
(2007)
Atherosclerosis
, vol.195
, pp. 31-38
-
-
Kamari, Y.1
-
88
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
Duewell P, et al. (2010) NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature. 464:1357–61.
-
(2010)
Nature
, vol.464
, pp. 1357-1361
-
-
Duewell, P.1
-
89
-
-
70450189795
-
Inflammation in atherosclerosis: From pathophysiology to practice
-
Libby P, Ridker PM, Hansson GK. (2009) Inflammation in atherosclerosis: from pathophysiology to practice. J. Am. Coll. Cardiol. 54:2129–38.
-
(2009)
J. Am. Coll. Cardiol
, vol.54
, pp. 2129-2138
-
-
Libby, P.1
Ridker, P.M.2
Hansson, G.K.3
-
90
-
-
80053644777
-
Interleukin-1beta inhibition and the prevention of recurrent cardiovascular events: Rationale and design of the Canakinumab Anti- inflammatory Thrombosis Outcomes Study (CANTOS)
-
Ridker PM, Thuren T, Zalewski A, Libby P. (2011) Interleukin-1beta inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti- inflammatory Thrombosis Outcomes Study (CANTOS). Am. Heart J. 162:597–605.
-
(2011)
Am. Heart J
, vol.162
, pp. 597-605
-
-
Ridker, P.M.1
Thuren, T.2
Zalewski, A.3
Libby, P.4
-
91
-
-
84870619337
-
Effects of interleukin- 1beta inhibition with canakinumab on hemoglobin A1c, lipids, C-reactive protein, interleukin-6, and fibrinogen: A phase IIb randomized, placebocontrolled trial
-
Ridker PM, et al. (2012) Effects of interleukin- 1beta inhibition with canakinumab on hemoglobin A1c, lipids, C-reactive protein, interleukin-6, and fibrinogen: a phase IIb randomized, placebocontrolled trial. Circulation. 126:2739–48.
-
(2012)
Circulation
, vol.126
, pp. 2739-2748
-
-
Ridker, P.M.1
-
92
-
-
47649105757
-
Anakinra, a recombinant human interleukin-1 receptor antagonist, inhibits apoptosis in experimental acute myocardial infarction
-
Abbate A, et al. (2008) Anakinra, a recombinant human interleukin-1 receptor antagonist, inhibits apoptosis in experimental acute myocardial infarction. Circulation. 117:2670–83.
-
(2008)
Circulation
, vol.117
, pp. 2670-2683
-
-
Abbate, A.1
-
93
-
-
77950279969
-
Interleukin-1beta modulation using a genetically engineered antibody prevents adverse cardiac remodelling following acute myocardial infarction in the mouse
-
Abbate A, et al. (2010) Interleukin-1beta modulation using a genetically engineered antibody prevents adverse cardiac remodelling following acute myocardial infarction in the mouse. Eur. J. Heart Fail. 12:319–22.
-
(2010)
Eur. J. Heart Fail
, vol.12
, pp. 319-322
-
-
Abbate, A.1
-
94
-
-
84874075401
-
Interleukin-1beta blockade improves cardiac remodelling after myocardial infarction without interrupting the inflammasome in the mouse. Exp
-
Toldo S, et al. (2013) Interleukin-1beta blockade improves cardiac remodelling after myocardial infarction without interrupting the inflammasome in the mouse. Exp. Physiol. 98:734–45.
-
(2013)
Physiol
, vol.98
, pp. 734-745
-
-
Toldo, S.1
-
95
-
-
77951665667
-
Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study)
-
Abbate A, et al. (2010) Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study). Am. J. Cardiol. 105:1371–77, e1371.
-
(2010)
Am. J. Cardiol. 105
, vol.1371
, pp. 1371-1377
-
-
Abbate, A.1
-
96
-
-
84876981024
-
Effects of interleukin-1 blockade with anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCUART2) pilot study]
-
Abbate A, et al. (2013) Effects of interleukin-1 blockade with anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCUART2) pilot study]. Am. J. Cardiol. 111:1394–400.
-
(2013)
Am. J. Cardiol
, vol.111
, pp. 1394-1400
-
-
Abbate, A.1
-
97
-
-
84891633095
-
Effects of interleukin- 1 blockade with anakinra on aerobic exercise capacity in patients with heart failure and preserved ejection fraction (From the D-HART pilot study)
-
Van Tassell BW, et al. (2014) Effects of interleukin- 1 blockade with anakinra on aerobic exercise capacity in patients with heart failure and preserved ejection fraction (from the D-HART pilot study). Am. J. Cardiol. 113:321–7.
-
(2014)
Am. J. Cardiol
, vol.113
, pp. 321-327
-
-
Van Tassell, B.W.1
-
98
-
-
79251570253
-
IL-1beta is overexpressed and aberrantly regulated in corticosteroid nonresponders with autoimmune inner ear disease
-
Pathak S, Goldofsky E, Vivas EX, Bonagura VR, Vambutas A. (2011) IL-1beta is overexpressed and aberrantly regulated in corticosteroid nonresponders with autoimmune inner ear disease. J. Immunol. 186:1870–9.
-
(2011)
J. Immunol
, vol.186
, pp. 1870-1879
-
-
Pathak, S.1
Goldofsky, E.2
Vivas, E.X.3
Bonagura, V.R.4
Vambutas, A.5
-
99
-
-
65549129527
-
Alternate splicing of interleukin-1 receptor type II (IL1R2) in vitro correlates with clinical glucocorticoid responsiveness in patients with AIED
-
Vambutas A, et al. (2009) Alternate splicing of interleukin-1 receptor type II (IL1R2) in vitro correlates with clinical glucocorticoid responsiveness in patients with AIED. PLoS One. 4:e5293.
-
(2009)
Plos One
, pp. 4
-
-
Vambutas, A.1
-
100
-
-
84907009758
-
Early efficacy trial of anakinra in corticosteroid-resistant autoimmune inner ear disease
-
Vambutas A, et al. (2014) Early efficacy trial of anakinra in corticosteroid-resistant autoimmune inner ear disease. J. Clin. Invest. 124:4115–22.
-
(2014)
J. Clin. Invest
, vol.124
, pp. 4115-4122
-
-
Vambutas, A.1
-
101
-
-
77951473388
-
Neurologic manifestations of the cryopyrin- associated periodic syndrome
-
Kitley JL, Lachmann HJ, Pinto A, Ginsberg L. (2010) Neurologic manifestations of the cryopyrin- associated periodic syndrome. Neurology. 74:1267–70.
-
(2010)
Neurology
, vol.74
, pp. 1267-1270
-
-
Kitley, J.L.1
Lachmann, H.J.2
Pinto, A.3
Ginsberg, L.4
-
102
-
-
79957456776
-
Current status of understanding the pathogenesis and management of patients with NOMID/CINCA
-
Goldbach-Mansky R. (2011) Current status of understanding the pathogenesis and management of patients with NOMID/CINCA. Curr. Rheumatol. Rep. 13:123–31.
-
(2011)
Curr. Rheumatol. Rep
, vol.13
, pp. 123-131
-
-
Goldbach-Mansky, R.1
-
103
-
-
84860389457
-
Two-year results from an open-label, multicentre, phase III study evaluating the safety and efficacy of canakinumab in patients with cryopyrinassociated periodic syndrome across different severity phenotypes
-
Kuemmerle-Deschner JB, et al. (2011) Two-year results from an open-label, multicentre, phase III study evaluating the safety and efficacy of canakinumab in patients with cryopyrinassociated periodic syndrome across different severity phenotypes. Ann. Rheum. Dis. 70:2095–102.
-
(2011)
Ann. Rheum. Dis
, vol.70
, pp. 2095-2102
-
-
Kuemmerle-Deschner, J.B.1
-
104
-
-
77951627028
-
Improvement of sensoneurinal hearing loss in a patient with Muckle-Wells syndrome treated with anakinra. Klin
-
Klein AK, Horneff G. (2011) Improvement of sensoneurinal hearing loss in a patient with Muckle-Wells syndrome treated with anakinra. Klin. Padiatr. 222:266–8.
-
(2011)
Padiatr
, vol.222
, pp. 266-268
-
-
Klein, A.K.1
Horneff, G.2
-
105
-
-
77955291693
-
Follow-up and quality of life of patients with cryopyrin-associated periodic syndromes treated with Anakinra
-
Lepore L, et al. (2011) Follow-up and quality of life of patients with cryopyrin-associated periodic syndromes treated with Anakinra. J. Pediatr. 157:310–315, e311.
-
(2011)
J. Pediatr. 157
, pp. 310-315
-
-
Lepore, L.1
-
106
-
-
77951159682
-
Effect of anakinra on arthropathy in CINCA/NOMID syndrome. Pediatr. Rheumatol
-
Miyamae T, et al. (2011) Effect of anakinra on arthropathy in CINCA/NOMID syndrome. Pediatr. Rheumatol. Online J. 8:9.
-
(2011)
Online J
, vol.8
, pp. 9
-
-
Miyamae, T.1
-
107
-
-
74849115591
-
Long-term efficacy of the interleukin-1 receptor antagonist anakinra in ten patients with neonatal-onset multisystem inflammatory disease/chronic infantile neurologic, cutaneous, articular syndrome
-
Neven B, et al. (2011) Long-term efficacy of the interleukin-1 receptor antagonist anakinra in ten patients with neonatal-onset multisystem inflammatory disease/chronic infantile neurologic, cutaneous, articular syndrome. Arthritis Rheum. 62:258–67.
-
(2011)
Arthritis Rheum
, vol.62
, pp. 258-267
-
-
Neven, B.1
-
108
-
-
82455212471
-
Muckle-Wells syndrome effectively treated with canakinumab: Is the recommended dosing schedule mandatory?
-
Mueller SM, Itin P, Haeusermann P. (2011) Muckle-Wells syndrome effectively treated with canakinumab: is the recommended dosing schedule mandatory? Dermatology. 223:113–8.
-
(2011)
Dermatology
, vol.223
, pp. 113-118
-
-
Mueller, S.M.1
Itin, P.2
Haeusermann, P.3
-
109
-
-
79952053673
-
Canakinumab (ACZ885, a fully human IgG1 anti-IL-1beta mAb) induces sustained remission in pediatric patients with cryopyrin-associated periodic syndrome (CAPS). Arthritis Res
-
Kuemmerle-Deschner JB, et al. (2011) Canakinumab (ACZ885, a fully human IgG1 anti-IL-1beta mAb) induces sustained remission in pediatric patients with cryopyrin-associated periodic syndrome (CAPS). Arthritis Res. Ther. 13:34.
-
(2011)
Ther
, vol.13
, pp. 34
-
-
Kuemmerle-Deschner, J.B.1
-
110
-
-
84855796483
-
Sustained remission of symptoms and improved health-related quality of life in patients with cryopyrin-associated periodic syndrome treated with canakinumab: Results of a double-blind placebo-controlled randomized withdrawal study. Arthritis Res
-
Kone-Paut I, et al. (2011) Sustained remission of symptoms and improved health-related quality of life in patients with cryopyrin-associated periodic syndrome treated with canakinumab: results of a double-blind placebo-controlled randomized withdrawal study. Arthritis Res. Ther. 13:202.
-
(2011)
Ther
, vol.13
, pp. 202
-
-
Kone-Paut, I.1
-
111
-
-
66649102432
-
Use of canakinumab in the cryopyrin-associated periodic syndrome
-
Lachmann HJ, et al. (2009) Use of canakinumab in the cryopyrin-associated periodic syndrome. N. Engl. J. Med. 360:2416–25.
-
(2009)
N. Engl. J. Med
, vol.360
, pp. 2416-2425
-
-
Lachmann, H.J.1
-
112
-
-
79956265355
-
Association of interleukin-1 gene polymorphisms with sudden sensorineural hearing loss and Meniere’s disease
-
Furuta T, et al. (2011) Association of interleukin-1 gene polymorphisms with sudden sensorineural hearing loss and Meniere’s disease. Int. J. Immunogenet. 38:249–54.
-
(2011)
Int. J. Immunogenet
, vol.38
, pp. 249-254
-
-
Furuta, T.1
-
113
-
-
0029671325
-
IL-1 beta does not cause neutrophil degranulation but does lead to IL- 6, IL-8, and nitrite/nitrate release when used in patients with cancer
-
Ogilvie AC, et al. (1996) IL-1 beta does not cause neutrophil degranulation but does lead to IL- 6, IL-8, and nitrite/nitrate release when used in patients with cancer. J. Immunol. 156:389–94.
-
(1996)
J. Immunol
, vol.156
, pp. 389-394
-
-
Ogilvie, A.C.1
-
114
-
-
0027489870
-
Hematological and immunomodulatory effects of an interleukin-1 receptor antagonist coinfusion during low-dose endotoxemia in healthy humans
-
Granowitz EV, et al. (1993) Hematological and immunomodulatory effects of an interleukin-1 receptor antagonist coinfusion during low-dose endotoxemia in healthy humans. Blood. 82:2985–90.
-
(1993)
Blood
, vol.82
, pp. 2985-2990
-
-
Granowitz, E.V.1
-
115
-
-
8444225132
-
Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist prevents
-
Hoffman HM, et al. (2004) Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist prevents. Lancet. 364:1779–85.
-
(2004)
Lancet
, vol.364
, pp. 1779-1785
-
-
Hoffman, H.M.1
-
116
-
-
0025108171
-
Preliminary report: Effects of interleukin-1 on platelet counts
-
Tewari A, Buhles WC Jr, Starnes HF Jr. (1990) Preliminary report: effects of interleukin-1 on platelet counts. Lancet. 336:712–4.
-
(1990)
Lancet
, vol.336
, pp. 712-714
-
-
Tewari, A.1
Buhles, W.C.2
Starnes, H.F.3
-
117
-
-
0030053054
-
Phase II trial of interleukin 1 alpha and indomethacin in treatment of metastatic melanoma
-
Janik JE, et al. (1996) Phase II trial of interleukin 1 alpha and indomethacin in treatment of metastatic melanoma. J. Natl. Cancer Inst. 88:44–9.
-
(1996)
J. Natl. Cancer Inst
, vol.88
, pp. 44-49
-
-
Janik, J.E.1
-
118
-
-
0033401640
-
The role of interleukin- 1 beta in the pathogenesis of multiple myeloma. Hematol. Oncol. Clin
-
Lust JA, Donovan KA. (1999) The role of interleukin- 1 beta in the pathogenesis of multiple myeloma. Hematol. Oncol. Clin. North Am. 13:1117–25.
-
(1999)
North Am
, vol.13
, pp. 1117-1125
-
-
Lust, J.A.1
Donovan, K.A.2
-
119
-
-
84855504820
-
Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1alpha
-
Berda-Haddad Y, et al. (2011) Sterile inflammation of endothelial cell-derived apoptotic bodies is mediated by interleukin-1alpha. Proc. Natl. Acad. Sci. U. S. A. 108:20684–9.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A
, vol.108
, pp. 20684-20689
-
-
Berda-Haddad, Y.1
-
120
-
-
84890420757
-
The interleukin-1alpha precursor is biologically active and is likely a key alarmin in the IL-1 family of cytokines. Front
-
Kim B, et al. (2013) The interleukin-1alpha precursor is biologically active and is likely a key alarmin in the IL-1 family of cytokines. Front. Immunol. 4:391.
-
(2013)
Immunol
, vol.4
, pp. 391
-
-
Kim, B.1
-
122
-
-
0027985033
-
Interleukin-1 induces interleukin-8 from endothelial cells by a juxacrine mechanism
-
Kaplanski G, et al. (1994) Interleukin-1 induces interleukin-8 from endothelial cells by a juxacrine mechanism. Blood 84:4242–8.
-
(1994)
Blood
, vol.84
, pp. 4242-4248
-
-
Kaplanski, G.1
-
123
-
-
0027212410
-
Activated platelets induce endothelial secretion of interleukin-8 in vitro via an interleukin-1-mediated event
-
Kaplanski G, et al. (1993) Activated platelets induce endothelial secretion of interleukin-8 in vitro via an interleukin-1-mediated event. Blood. 81:2492–5.
-
(1993)
Blood
, vol.81
, pp. 2492-2495
-
-
Kaplanski, G.1
-
124
-
-
80555133279
-
IL-1α and IL-1β recruit different myeloid cells and promote different stages of sterile inflammation
-
Rider P, et al. (2011) IL-1α and IL-1β recruit different myeloid cells and promote different stages of sterile inflammation. J. Immunol. 187:4835–43.
-
(2011)
J. Immunol
, vol.187
, pp. 4835-4843
-
-
Rider, P.1
-
125
-
-
84895502154
-
Non-redundant properties of IL-1alpha and IL-1beta during acute colon inflammation in mice
-
Bersudsky M, et al. (2014) Non-redundant properties of IL-1alpha and IL-1beta during acute colon inflammation in mice. Gut. 63:598–609.
-
(2014)
Gut
, vol.63
, pp. 598-609
-
-
Bersudsky, M.1
-
127
-
-
0024588193
-
IgG autoantibodies against interleukin 1 alpha in sera of normal individuals. Scand
-
Svenson M, Poulsen LK, Fomsgaard A, Bendtzen K. (1989) IgG autoantibodies against interleukin 1 alpha in sera of normal individuals. Scand. J. Immunol. 29:489–92.
-
(1989)
J. Immunol
, vol.29
, pp. 489-492
-
-
Svenson, M.1
Poulsen, L.K.2
Fomsgaard, A.3
Bendtzen, K.4
-
128
-
-
34447116244
-
Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat
-
Chen CJ, et al. (2007) Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat. Med. 13:851–6.
-
(2007)
Med
, vol.13
, pp. 851-856
-
-
Chen, C.J.1
-
129
-
-
0027469684
-
The effects of treatment with interleukin-1 alpha on platelet recovery after high-dose carboplatin
-
Smith JW 2nd, et al. (1993) The effects of treatment with interleukin-1 alpha on platelet recovery after high-dose carboplatin. N. Engl. J. Med. 328:756–61.
-
(1993)
N. Engl. J. Med
, vol.328
, pp. 756-761
-
-
Smith, J.W.1
-
130
-
-
0020678196
-
Stimulation of muscle protein degradation and prostaglandin E2 release by leukocytic pyrogen (Interleukin-1): A mechanism for the increased degradation of muscle proteins during fever
-
Baracos V, Rodemann HP, Dinarello CA, Goldberg AL. (1983) Stimulation of muscle protein degradation and prostaglandin E2 release by leukocytic pyrogen (interleukin-1): a mechanism for the increased degradation of muscle proteins during fever. N. Engl. J. Med. 308:553–8.
-
(1983)
N. Engl. J. Med
, vol.308
, pp. 553-558
-
-
Baracos, V.1
Rodemann, H.P.2
Dinarello, C.A.3
Goldberg, A.L.4
-
131
-
-
0037418208
-
IL-1 is required for tumor invasiveness and angiogenesis
-
Voronov E, et al. (2003) IL-1 is required for tumor invasiveness and angiogenesis. Proc. Natl. Acad. Sci. U. S. A. 100:2645–50.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A
, vol.100
, pp. 2645-2650
-
-
Voronov, E.1
-
132
-
-
84862806229
-
Interleukin-1 receptor antagonist reverses stroke-associated peripheral immune suppression
-
Smith CJ, et al. (2012) Interleukin-1 receptor antagonist reverses stroke-associated peripheral immune suppression. Cytokine. 58:384–9.
-
(2012)
Cytokine
, vol.58
, pp. 384-389
-
-
Smith, C.J.1
-
133
-
-
84857141296
-
Cancer-related inflammation: Common themes and therapeutic opportunities. Semin
-
Balkwill FR, Mantovani A. (2012) Cancer-related inflammation: common themes and therapeutic opportunities. Semin. Cancer Biol. 22:33–40.
-
(2012)
Cancer Biol
, vol.22
, pp. 33-40
-
-
Balkwill, F.R.1
Mantovani, A.2
-
134
-
-
33847060965
-
Interleukin-1beta-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors
-
Krelin Y, et al. (2007) Interleukin-1beta-driven inflammation promotes the development and invasiveness of chemical carcinogen-induced tumors. Cancer Res. 67:1062–71.
-
(2007)
Cancer Res
, vol.67
, pp. 1062-1071
-
-
Krelin, Y.1
-
135
-
-
77954551165
-
Why not treat human cancer with interleukin-1 blockade?
-
Dinarello CA. (2010) Why not treat human cancer with interleukin-1 blockade? Cancer Metastasis Rev. 29:317–29.
-
(2010)
Cancer Metastasis Rev
, vol.29
, pp. 317-329
-
-
Dinarello, C.A.1
-
136
-
-
84899980380
-
Interleukin-1alpha neutralisation in patients with cancer
-
Dinarello CA. (2014) Interleukin-1alpha neutralisation in patients with cancer. Lancet Oncol. 15:552–3.
-
(2014)
Lancet Oncol
, vol.15
, pp. 552-553
-
-
Dinarello, C.A.1
-
137
-
-
84864545087
-
Treating inflammation by blocking interleukin- 1 in a broad spectrum of diseases. Nat
-
Dinarello CA, Simon A, van der Meer JW. (2012) Treating inflammation by blocking interleukin- 1 in a broad spectrum of diseases. Nat. Rev. Drug Discov. 11:633–52.
-
(2012)
Rev. Drug Discov
, vol.11
, pp. 633-652
-
-
Dinarello, C.A.1
Simon, A.2
Van Der Meer, J.W.3
-
138
-
-
84864569149
-
A retrospective review of autoinflammatory diseases in Saudi children at a rheumatology clinic
-
Alenazi A, Al Sonbul A, Al Jumaah S, Al Mehaidib A, Al-Mayouf SM. (2012) A retrospective review of autoinflammatory diseases in Saudi children at a rheumatology clinic. Ann. Saudi Med. 32:43–8.
-
(2012)
Ann. Saudi Med
, vol.32
, pp. 43-48
-
-
Alenazi, A.1
Al Sonbul, A.2
Al Jumaah, S.3
Al Mehaidib, A.4
Al-Mayouf, S.M.5
-
139
-
-
41849105723
-
The efficacy of anakinra in an adolescent with colchicine-resistant familial Mediterranean fever
-
Calligaris L, Marchetti F, Tommasini A, Ventura A. (2008) The efficacy of anakinra in an adolescent with colchicine-resistant familial Mediterranean fever. Eur. J. Pediatr. 167:695–6.
-
(2008)
Eur. J. Pediatr
, vol.167
, pp. 695-696
-
-
Calligaris, L.1
Marchetti, F.2
Tommasini, A.3
Ventura, A.4
-
140
-
-
33745631232
-
The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL- 1beta production
-
Chae JJ, et al. (2006) The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL- 1beta production. Proc. Natl. Acad. Sci. U. S. A. 103:9982–7.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A
, vol.103
, pp. 9982-9987
-
-
Chae, J.J.1
-
141
-
-
79955138270
-
Interleukin-1 targeting drugs in familial Mediterranean fever: A case series and a review of the literature. Semin
-
Meinzer U, et al. (2011) Interleukin-1 targeting drugs in familial Mediterranean fever: a case series and a review of the literature. Semin. Arthritis Rheum. 41:265–71.
-
(2011)
Arthritis Rheum
, vol.41
, pp. 265-271
-
-
Meinzer, U.1
-
142
-
-
57849127198
-
Anakinra suppresses familial Mediterranean fever crises in a colchicineresistant patient. Neth
-
Mitroulis I, Papadopoulos VP, Konstantinidis T, Ritis K. (2008) Anakinra suppresses familial Mediterranean fever crises in a colchicineresistant patient. Neth. J. Med. 66:489–91.
-
(2008)
J. Med
, vol.66
, pp. 489-491
-
-
Mitroulis, I.1
Papadopoulos, V.P.2
Konstantinidis, T.3
Ritis, K.4
-
143
-
-
58449114163
-
Successful treatment of familial Mediterranean fever with anakinra and outcome after renal transplantation. Nephrol. Dial
-
Moser C, et al. (2009) Successful treatment of familial Mediterranean fever with anakinra and outcome after renal transplantation. Nephrol. Dial. Transplant. 24:676–8.
-
(2009)
Transplant
, vol.24
, pp. 676-678
-
-
Moser, C.1
-
144
-
-
79952425658
-
Anti-interleukin 1 treatment for patients with familial Mediterranean fever resistant to colchicine
-
Ozen S, Bilginer Y, Aktay Ayaz N, Calguneri M. (2011) Anti-interleukin 1 treatment for patients with familial Mediterranean fever resistant to colchicine. J. Rheumatol. 38:516–8.
-
(2011)
J. Rheumatol
, vol.38
, pp. 516-518
-
-
Ozen, S.1
Bilginer, Y.2
Aktay Ayaz, N.3
Calguneri, M.4
-
145
-
-
77954594556
-
Transmission of familial Mediterranean fever mutation after bone marrow transplantation and successful treatment with anakinra
-
Petropoulou AD, Robin M, Socie G, Galicier L. (2011) Transmission of familial Mediterranean fever mutation after bone marrow transplantation and successful treatment with anakinra. Transplantation. 90:102–3.
-
(2011)
Transplantation
, vol.90
, pp. 102-103
-
-
Petropoulou, A.D.1
Robin, M.2
Socie, G.3
Galicier, L.4
-
146
-
-
84871914109
-
Dramatic beneficial effect of interleukin-1 inhibitor treatment in patients with familial Mediterranean fever complicated with amyloidosis and renal failure. Nephrol. Dial
-
Stankovic Stojanovic K, et al. (2012) Dramatic beneficial effect of interleukin-1 inhibitor treatment in patients with familial Mediterranean fever complicated with amyloidosis and renal failure. Nephrol. Dial. Transplant. 27:1898–901.
-
(2012)
Transplant
, vol.27
, pp. 1898-1901
-
-
Stankovic Stojanovic, K.1
-
147
-
-
77949884645
-
Anti-IL-1 treatment for secondary amyloidosis in an ado lescent with FMF and Behcet’s disease. Clin
-
Bilginer Y, Ayaz NA, Ozen S. (2010) Anti-IL-1 treatment for secondary amyloidosis in an ado lescent with FMF and Behcet’s disease. Clin. Rheumatol. 29:209–10.
-
(2010)
Rheumatol
, vol.29
, pp. 209-210
-
-
Bilginer, Y.1
Ayaz, N.A.2
Ozen, S.3
-
148
-
-
84880800600
-
IL-1beta biological treatment of familial Mediterranean fever. Clin
-
Soriano A, Verecchia E, Afeltra A, Landolfi R, Manna R. (2013) IL-1beta biological treatment of familial Mediterranean fever. Clin. Rev. Allergy Immunol. 45:117–30.
-
(2013)
Rev. Allergy Immunol
, vol.45
, pp. 117-130
-
-
Soriano, A.1
Verecchia, E.2
Afeltra, A.3
Landolfi, R.4
Manna, R.5
-
149
-
-
84880817775
-
Efficacy and safety of biologic treatments in Familial Mediterranean Fever
-
Akgul O, Kilic E, Kilic G, Ozgocmen S. (2013) Efficacy and safety of biologic treatments in Familial Mediterranean Fever. Am. J. Med. Sci. 346:137–41.
-
(2013)
Am. J. Med. Sci
, vol.346
, pp. 137-141
-
-
Akgul, O.1
Kilic, E.2
Kilic, G.3
Ozgocmen, S.4
-
150
-
-
84885912333
-
Myositis in a patient with familial Mediterranean fever and spondyloarthritis successfully treated with anakinra
-
Estublier C, Stankovic Stojanovic K, Bergerot JF, Broussolle C, Seve P. (2013) Myositis in a patient with familial Mediterranean fever and spondyloarthritis successfully treated with anakinra. Joint Bone Spine. 80:645–9.
-
(2013)
Joint Bone Spine
, vol.80
, pp. 645-649
-
-
Estublier, C.1
Stankovic Stojanovic, K.2
Bergerot, J.F.3
Broussolle, C.4
Seve, P.5
-
151
-
-
84901679747
-
Colchicine failure in familial Mediterranean fever and potential alternatives: Embarking on the anakinra trial
-
Ben-Zvi I, Livneh A. (2014) Colchicine failure in familial Mediterranean fever and potential alternatives: embarking on the anakinra trial. IMAJ. 16:271–3.
-
(2014)
IMAJ
, vol.16
, pp. 271-273
-
-
Ben-Zvi, I.1
Livneh, A.2
-
152
-
-
84866426987
-
Mutation negative” familial cold autoinflammatory syndrome (FCAS) in an 8-year-old boy: Clinical course and functional studies
-
Hedrich CM, et al. (2012) “Mutation negative” familial cold autoinflammatory syndrome (FCAS) in an 8-year-old boy: clinical course and functional studies. Rheumatol. Int. 32:2629–36.
-
(2012)
Rheumatol. Int
, vol.32
, pp. 2629-2636
-
-
Hedrich, C.M.1
-
153
-
-
33749990239
-
Anakinra prevents symptoms of familial cold autoinflammatory syndrome and Raynaud’s disease
-
Metyas SK, Hoffman HM. (2006) Anakinra prevents symptoms of familial cold autoinflammatory syndrome and Raynaud’s disease. J. Rheumatol. 33:2085–7.
-
(2006)
J. Rheumatol
, vol.33
, pp. 2085-2087
-
-
Metyas, S.K.1
Hoffman, H.M.2
-
154
-
-
1042290321
-
Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthr
-
Hawkins PN, Lachmann HJ, Aganna E, McDermott MF. (2004) Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthr. Rheumat. 50:607–12.
-
(2004)
Rheumat
, vol.50
, pp. 607-612
-
-
Hawkins, P.N.1
Lachmann, H.J.2
Aganna, E.3
Mc dermott, M.F.4
-
155
-
-
0037792866
-
Interleukin-1 receptor antagonist in the Muckle-Wells syndrome
-
Hawkins PN, Lachmann HJ, McDermott MF. (2003) Interleukin-1 receptor antagonist in the Muckle-Wells syndrome. N. Engl. J. Med. 348:2583–4.
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 2583-2584
-
-
Hawkins, P.N.1
Lachmann, H.J.2
Mc dermott, M.F.3
-
156
-
-
33645125321
-
Hearing improvement in a patient with variant Muckle-Wells syndrome in response to interleukin 1 receptor antagonism
-
Rynne M, Maclean C, Bybee A, McDermott MF, Emery P. (2006) Hearing improvement in a patient with variant Muckle-Wells syndrome in response to interleukin 1 receptor antagonism. Ann. Rheum. Dis. 65:533–4.
-
(2006)
Ann. Rheum. Dis
, vol.65
, pp. 533-534
-
-
Rynne, M.1
Maclean, C.2
Bybee, A.3
Mc dermott, M.F.4
Emery, P.5
-
157
-
-
82655170808
-
NLRP3 E311K mutation in a large family with Muckle- Wells syndrome: Description of a heterogeneous phenotype and response to treatment
-
Kuemmerle-Deschner JB, et al. (2011) NLRP3 E311K mutation in a large family with Muckle- Wells syndrome: description of a heterogeneous phenotype and response to treatment. Arthritis Res. Ther. 13:196.
-
(2011)
Arthritis Res. Ther
, vol.13
, pp. 196
-
-
Kuemmerle-Deschner, J.B.1
-
158
-
-
84878246239
-
Treatment of Muckle-Wells syndrome: Analysis of two IL- 1-blocking regimens
-
Kuemmerle-Deschner JB, et al. (2013) Treatment of Muckle-Wells syndrome: analysis of two IL- 1-blocking regimens. Arthritis Res. Ther. 15:64.
-
(2013)
Arthritis Res. Ther
, vol.15
, pp. 64
-
-
Kuemmerle-Deschner, J.B.1
-
159
-
-
84883106944
-
Muckle-Wells syndrome: A treatable cause of congenital sensorineural hearing loss
-
Stew BT, Fishpool SJ, Owens D, Quine S. (2013) Muckle-Wells syndrome: a treatable cause of congenital sensorineural hearing loss. B-ENT. 9:161–3.
-
(2013)
B-ENT
, vol.9
, pp. 161-163
-
-
Stew, B.T.1
Fishpool, S.J.2
Owens, D.3
Quine, S.4
-
160
-
-
84888136040
-
Muckle-Wells syndrome without mutation in exon 3 of the NLRP3 gene, identified by evidence of excessive monocyte production of functional interleukin 1beta and rapid response to anakinra
-
Sabroe RA, et al. (2013) Muckle-Wells syndrome without mutation in exon 3 of the NLRP3 gene, identified by evidence of excessive monocyte production of functional interleukin 1beta and rapid response to anakinra. Clin. Exp. Dermatol.
-
(2013)
Clin. Exp. Dermatol
-
-
Sabroe, R.A.1
-
161
-
-
84877850864
-
Nephrotic syndrome and AA amyloidosis revealing adult-onset cryopyrin- associated periodic syndrome. Ren
-
Enriquez R, et al. (2013) Nephrotic syndrome and AA amyloidosis revealing adult-onset cryopyrin- associated periodic syndrome. Ren. Fail. 35:738–41.
-
(2013)
Fail
, vol.35
, pp. 738-741
-
-
Enriquez, R.1
-
163
-
-
17244381937
-
Interleukin-1 blockade by anakinra improves clinical symptoms in patients with neonatalonset multisystem inflammatory disease
-
Lovell DJ, Bowyer SL, Solinger AM. (2005) Interleukin-1 blockade by anakinra improves clinical symptoms in patients with neonatalonset multisystem inflammatory disease. Arthritis Rheum. 52:1283–6.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1283-1286
-
-
Lovell, D.J.1
Bowyer, S.L.2
Solinger, A.M.3
-
164
-
-
84863228835
-
Sustained response and prevention of damage progression in patients with neonatal-onset multisystem inflammatory disease treated with anakinra: A cohort study to determine three- and five-year outcomes
-
Sibley CH, et al. (2012) Sustained response and prevention of damage progression in patients with neonatal-onset multisystem inflammatory disease treated with anakinra: a cohort study to determine three- and five-year outcomes. Arthritis Rheum. 64:2375–86.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 2375-2386
-
-
Sibley, C.H.1
-
165
-
-
84870722327
-
Homeostatic tissue responses in skin biopsies from NOMID patients with constitutive overproduction of IL-1beta
-
Aubert P, et al. (2012) Homeostatic tissue responses in skin biopsies from NOMID patients with constitutive overproduction of IL-1beta. PLoS One. 7:e49408.
-
(2012)
Plos One
, pp. 7
-
-
Aubert, P.1
-
166
-
-
84877598469
-
Microarray-based gene expression profiling in patients with cryopyrinassociated periodic syndromes defines a diseaserelated signature and IL-1-responsive transcripts
-
Balow JE Jr, et al. (2013) Microarray-based gene expression profiling in patients with cryopyrinassociated periodic syndromes defines a diseaserelated signature and IL-1-responsive transcripts. Ann. Rheum. Dis. 72:1064–70.
-
(2013)
Ann. Rheum. Dis
, vol.72
, pp. 1064-1070
-
-
Balow, J.E.1
-
167
-
-
39549122472
-
Dramatic improvement following interleukin 1beta blockade in tumor necrosis factor receptor-1-associated syndrome (TRAPS) resistant to anti-TNF-alpha therapy
-
Sacre K, et al. (2008) Dramatic improvement following interleukin 1beta blockade in tumor necrosis factor receptor-1-associated syndrome (TRAPS) resistant to anti-TNF-alpha therapy. J. Rheumatol. 35:357–8.
-
(2008)
J. Rheumatol
, vol.35
, pp. 357-358
-
-
Sacre, K.1
-
168
-
-
3843110981
-
Beneficial response to interleukin-1 receptor antagonist in TRAPS
-
Simon A, et al. (2004) Beneficial response to interleukin-1 receptor antagonist in TRAPS. Am. J. Med. 117:208–10.
-
(2004)
Am. J. Med
, vol.117
, pp. 208-210
-
-
Simon, A.1
-
169
-
-
43949128071
-
Persistent efficacy of anakinra in patients with tumor necrosis factor receptor-associated periodic syndrome
-
Gattorno M, et al. (2008) Persistent efficacy of anakinra in patients with tumor necrosis factor receptor-associated periodic syndrome. Arthritis Rheum. 58:1516–20.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1516-1520
-
-
Gattorno, M.1
-
170
-
-
38849160958
-
Falling into TRAPS: Receptor misfolding in the TNF receptor 1-associated periodic fever syndrome. Arthritis Res
-
Kimberley FC, Lobito AA, Siegel RM, Screaton GR. (2007) Falling into TRAPS: receptor misfolding in the TNF receptor 1-associated periodic fever syndrome. Arthritis Res. Ther. 9:217.
-
(2007)
Ther
, vol.9
, pp. 217
-
-
Kimberley, F.C.1
Lobito, A.A.2
Siegel, R.M.3
Screaton, G.R.4
-
171
-
-
78650552920
-
Recurrent pericarditis caused by a rare mutation in the TNFRSF1A gene and with excellent response to anakinra treatment. Clin. Exp
-
Cantarini L, Lucherini OM, Cimaz R, Galeazzi M. (2010) Recurrent pericarditis caused by a rare mutation in the TNFRSF1A gene and with excellent response to anakinra treatment. Clin. Exp. Rheumatol. 28:802.
-
(2010)
Rheumatol
, vol.28
, pp. 802
-
-
Cantarini, L.1
Lucherini, O.M.2
Cimaz, R.3
Galeazzi, M.4
-
172
-
-
84871097835
-
Anakinra for a refractory case of intermittent hydrarthrosis with a TRAPS-related gene mutation
-
Andres M, Pascual E. (2013) Anakinra for a refractory case of intermittent hydrarthrosis with a TRAPS-related gene mutation. Ann. Rheum. Dis. 72:155.
-
(2013)
Ann. Rheum. Dis
, vol.72
, pp. 155
-
-
Andres, M.1
Pascual, E.2
-
173
-
-
84884198548
-
First report of circulating microRNAs in tumour necrosis factor receptor- associated periodic syndrome (TRAPS)
-
Lucherini OM, et al. (2013) First report of circulating microRNAs in tumour necrosis factor receptor- associated periodic syndrome (TRAPS). PLoS One. 8:e73443.
-
(2013)
Plos One
, pp. 8
-
-
Lucherini, O.M.1
-
174
-
-
23844552119
-
Effect of etanercept and anakinra on inflammatory attacks in the hyper-IgD syndrome: Introducing a vaccination provocation model. Neth
-
Bodar EJ, van der Hilst JC, Drenth JP, van der Meer JW, Simon A. (2005) Effect of etanercept and anakinra on inflammatory attacks in the hyper-IgD syndrome: introducing a vaccination provocation model. Neth. J. Med. 63:260–4.
-
(2005)
J. Med
, vol.63
, pp. 260-264
-
-
Bodar, E.J.1
Van Der Hilst, J.C.2
Drenth, J.P.3
Van Der Meer, J.W.4
Simon, A.5
-
175
-
-
33845807104
-
Anakinra is safe and effective in controlling hyperimmunoglobulinaemia D syndrome-associated febrile crisis
-
Cailliez M, et al. (2006) Anakinra is safe and effective in controlling hyperimmunoglobulinaemia D syndrome-associated febrile crisis. J. Inherit. Metab. Dis. 29:763.
-
(2006)
J. Inherit. Metab. Dis
, vol.29
, pp. 763
-
-
Cailliez, M.1
-
176
-
-
80052023093
-
Hyper-IgD syndrome or mevalonate kinase deficiency
-
Stoffels M, Simon A. (2011) Hyper-IgD syndrome or mevalonate kinase deficiency. Curr. Opin. Rheumatol. 23:419–23.
-
(2011)
Curr. Opin. Rheumatol
, vol.23
, pp. 419-423
-
-
Stoffels, M.1
Simon, A.2
-
177
-
-
33846139340
-
Pathogenesis of familial periodic fever syndromes or hereditary autoinflammatory syndromes
-
Simon A, van der Meer JW. (2007) Pathogenesis of familial periodic fever syndromes or hereditary autoinflammatory syndromes. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292:86–98.
-
(2007)
Am. J. Physiol. Regul. Integr. Comp. Physiol
, vol.292
, pp. 86-98
-
-
Simon, A.1
Van Der Meer, J.W.2
-
178
-
-
84860389029
-
On-demand anakinra treatment is effective in mevalonate kinase deficiency
-
Bodar EJ, et al. (2011) On-demand anakinra treatment is effective in mevalonate kinase deficiency. Ann. Rheum. Dis. 70:2155–8.
-
(2011)
Ann. Rheum. Dis
, vol.70
, pp. 2155-2158
-
-
Bodar, E.J.1
-
179
-
-
84857115753
-
Etanercept and anakinra can prolong febrile episodes in patients with hyperimmunoglobulin D and periodic fever syndrome. Rheumatol
-
Shendi HM, Walsh D, Edgar JD. (2012) Etanercept and anakinra can prolong febrile episodes in patients with hyperimmunoglobulin D and periodic fever syndrome. Rheumatol. Int. 32:249–51.
-
(2012)
Int
, vol.32
, pp. 249-251
-
-
Shendi, H.M.1
Walsh, D.2
Edgar, J.D.3
-
180
-
-
84857458569
-
Pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH)--a new autoinflammatory syndrome distinct from PAPA syndrome
-
Braun-Falco M, Kovnerystyy O, Lohse P, Ruzicka T. (2012) Pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH)--a new autoinflammatory syndrome distinct from PAPA syndrome. J. Am. Acad. Dermatol. 66:409–15.
-
(2012)
J. Am. Acad. Dermatol
, vol.66
, pp. 409-415
-
-
Braun-Falco, M.1
Kovnerystyy, O.2
Lohse, P.3
Ruzicka, T.4
-
181
-
-
71149085612
-
Targeted treatment of pyoderma gangrenosum in PAPA (Pyogenic arthritis, pyoderma gangrenosum and acne) syndrome with the recombinant human interleukin-1 receptor antagonist anakinra
-
Brenner M, Ruzicka T, Plewig G, Thomas P, Herzer P. (2009) Targeted treatment of pyoderma gangrenosum in PAPA (pyogenic arthritis, pyoderma gangrenosum and acne) syndrome with the recombinant human interleukin-1 receptor antagonist anakinra. Br. J. Dermatol. 161:1199–201.
-
(2009)
Br. J. Dermatol
, vol.161
, pp. 1199-1201
-
-
Brenner, M.1
Ruzicka, T.2
Plewig, G.3
Thomas, P.4
Herzer, P.5
-
183
-
-
79955825388
-
Variable expression and treatment of PAPA syndrome
-
Schellevis MA, et al. (2011) Variable expression and treatment of PAPA syndrome. Ann. Rheum. Dis. 70:1168–70.
-
(2011)
Ann. Rheum. Dis
, vol.70
, pp. 1168-1170
-
-
Schellevis, M.A.1
-
184
-
-
0344823965
-
Pyrin binds the PSTPIP1/ CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
-
Shoham NG, et al. (2003) Pyrin binds the PSTPIP1/ CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway. Proc. Natl. Acad. Sci. U. S. A. 100:13501–6.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A
, vol.100
, pp. 13501-13506
-
-
Shoham, N.G.1
-
185
-
-
84861808859
-
Brief report: Genotype, phenotype, and clinical course in five patients with PAPA syndrome (pyogenic sterile arthritis, pyoderma gangrenosum, and acne)
-
Demidowich AP, et al. (2012) Brief report: genotype, phenotype, and clinical course in five patients with PAPA syndrome (pyogenic sterile arthritis, pyoderma gangrenosum, and acne). Arthritis Rheum. 64:2022–7.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 2022-2027
-
-
Demidowich, A.P.1
-
186
-
-
84867802417
-
An overview of interleukin-1 receptor antagonist, anakinra, in the treatment of cutaneous diseases
-
Pazyar N, Feily A, Yaghoobi R. (2012) An overview of interleukin-1 receptor antagonist, anakinra, in the treatment of cutaneous diseases. Curr. Clin. Pharmacol. 7:271–5.
-
(2012)
Curr. Clin. Pharmacol
, vol.7
, pp. 271-275
-
-
Pazyar, N.1
Feily, A.2
Yaghoobi, R.3
-
187
-
-
84884909510
-
Autoinflammatory skin disorders in inflammatory bowel diseases, pyoderma gangrenosum and Sweet’s syndrome: A comprehensive review and disease classification criteria. Clin
-
Marzano AV, et al. (2013) Autoinflammatory skin disorders in inflammatory bowel diseases, pyoderma gangrenosum and Sweet’s syndrome: a comprehensive review and disease classification criteria. Clin. Rev. Allergy Immunol. 45:202–10.
-
(2013)
Rev. Allergy Immunol
, vol.45
, pp. 202-210
-
-
Marzano, A.V.1
-
188
-
-
66649113371
-
An autoinflammatory disease due to homozygous deletion of the IL1RN locus
-
Reddy S, et al. (2009) An autoinflammatory disease due to homozygous deletion of the IL1RN locus. N. Engl. J. Med. 360:2438–44.
-
(2009)
N. Engl. J. Med
, vol.360
, pp. 2438-2444
-
-
Reddy, S.1
-
189
-
-
66649121678
-
An autoinflammatory disease with deficiency of the interleukin-1- receptor antagonist
-
Aksentijevich I, et al. (2009) An autoinflammatory disease with deficiency of the interleukin-1- receptor antagonist. N. Engl. J. Med. 360:2426–37.
-
(2009)
N. Engl. J. Med
, vol.360
, pp. 2426-2437
-
-
Aksentijevich, I.1
-
190
-
-
84871792865
-
Chronic recurrent multifocal osteomyelitis and deficiency of interleukin- 1-receptor antagonist
-
Sakran W, et al. (2013) Chronic recurrent multifocal osteomyelitis and deficiency of interleukin- 1-receptor antagonist. Pediatr. Infect. Dis. J. 32:94.
-
(2013)
Pediatr. Infect. Dis. J
, vol.32
, pp. 94
-
-
Sakran, W.1
-
191
-
-
36048981805
-
NOD2 gene-associated pediatric granulomatous arthritis: Clinical diversity, novel and recurrent mutations, and evidence of clinical improvement with interleukin- 1 blockade in a Spanish cohort
-
Arostegui JI, et al. (2007) NOD2 gene-associated pediatric granulomatous arthritis: clinical diversity, novel and recurrent mutations, and evidence of clinical improvement with interleukin- 1 blockade in a Spanish cohort. Arthritis Rheum. 56:3805–13.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3805-3813
-
-
Arostegui, J.I.1
-
192
-
-
82955178718
-
Miscellaneous non-inflammatory musculoskeletal conditions: Blau syndrome. Best Pract. Res. Clin
-
Punzi L, Gava A, Galozzi P, Sfriso P. (2011) Miscellaneous non-inflammatory musculoskeletal conditions: Blau syndrome. Best Pract. Res. Clin. Rheumatol. 25:703–14.
-
(2011)
Rheumatol
, vol.25
, pp. 703-714
-
-
Punzi, L.1
Gava, A.2
Galozzi, P.3
Sfriso, P.4
-
193
-
-
84856551102
-
Clinical, genetic, and therapeutic diversity in 2 patients with severe mevalonate kinase deficiency
-
Ruiz Gomez A, et al. (2012) Clinical, genetic, and therapeutic diversity in 2 patients with severe mevalonate kinase deficiency. Pediatrics. 129:e535–9.
-
(2012)
Pediatrics
, vol.129
-
-
Ruiz Gomez, A.1
-
194
-
-
84873726217
-
Efficacy of anti-IL-1 treatment in Majeed syndrome
-
Herlin T, et al. (2013) Efficacy of anti-IL-1 treatment in Majeed syndrome. Ann. Rheum. Dis. 72:410–3.
-
(2013)
Ann. Rheum. Dis
, vol.72
, pp. 410-413
-
-
Herlin, T.1
-
195
-
-
57749177516
-
Schnitzler syndrome: Report on a fourteen-year course of the disease and an overview of information on the disease. Vnitr
-
Adam Z, et al. (2008) Schnitzler syndrome: report on a fourteen-year course of the disease and an overview of information on the disease. Vnitr. Lek. 54:1140–53.
-
(2008)
Lek
, vol.54
, pp. 1140-1153
-
-
Adam, Z.1
-
196
-
-
77955349737
-
Successful treatment of Schnitzler’s syndrome with anakinra after failure of rituximab trial
-
Cascavilla N, Bisceglia M, D’Arena G. (2010) Successful treatment of Schnitzler’s syndrome with anakinra after failure of rituximab trial. Int. J. Immunopathol. Pharmacol. 23:633–6.
-
(2010)
Int. J. Immunopathol. Pharmacol
, vol.23
, pp. 633-636
-
-
Cascavilla, N.1
Bisceglia, M.2
D’arena, G.3
-
197
-
-
33645119818
-
Beneficial response to anakinra and thalidomide in Schnitzler’s syndrome
-
De Koning HD, et al. (2006) Beneficial response to anakinra and thalidomide in Schnitzler’s syndrome. Ann Rheum Dis. 65:542–4.
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 542-544
-
-
De Koning, H.D.1
-
198
-
-
34447267950
-
Schnitzler syndrome: Treatment failure to rituximab but response to anakinra
-
Eiling E, Moller M, Kreiselmaier I, Brasch J, Schwarz T. (2007) Schnitzler syndrome: treatment failure to rituximab but response to anakinra. J. Am. Acad. Dermatol. 57:361–4.
-
(2007)
J. Am. Acad. Dermatol
, vol.57
, pp. 361-364
-
-
Eiling, E.1
Moller, M.2
Kreiselmaier, I.3
Brasch, J.4
Schwarz, T.5
-
199
-
-
79952266366
-
Treatment of Schnitzler’s syndrome with anakinra: Report of three cases and review of the literature. Scand
-
Gran JT, Midtvedt O, Haug S, Aukrust P. (2011) Treatment of Schnitzler’s syndrome with anakinra: report of three cases and review of the literature. Scand. J. Rheumatol. 40:74–9.
-
(2011)
J. Rheumatol
, vol.40
, pp. 74-79
-
-
Gran, J.T.1
Midtvedt, O.2
Haug, S.3
Aukrust, P.4
-
200
-
-
78649781218
-
The Schnitzler syndrome. Orphanet
-
Lipsker D. (2010) The Schnitzler syndrome. Orphanet J. Rare Dis. 5:38.
-
(2010)
J. Rare Dis
, vol.5
, pp. 38
-
-
Lipsker, D.1
-
201
-
-
22244467732
-
Successful treatment of refractory Schnitzler syndrome with anakinra: Comment on the article by Hawkins et al
-
Martinez-Taboada VM, Fontalba A, Blanco R, Fernandez-Luna JL. (2005) Successful treatment of refractory Schnitzler syndrome with anakinra: comment on the article by Hawkins et al. Arthritis Rheum. 52:2226–7.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2226-2227
-
-
Martinez-Taboada, V.M.1
Fontalba, A.2
Blanco, R.3
Fernandez-Luna, J.L.4
-
202
-
-
70449365692
-
Schnitzler syndrome: Response to anakinra in two cases and a review of the literature
-
Schuster C, et al. (2009) Schnitzler syndrome: response to anakinra in two cases and a review of the literature. Int. J. Dermatol. 48:1190–4.
-
(2009)
Int. J. Dermatol
, vol.48
, pp. 1190-1194
-
-
Schuster, C.1
-
203
-
-
84856746600
-
Schnitzler’s syndrome associated with pancreatitis: A disease of IL-1 dysregulation. Clin
-
Larocca CA, et al. (2012) Schnitzler’s syndrome associated with pancreatitis: a disease of IL-1 dysregulation. Clin. Rheumatol. 31:169–74.
-
(2012)
Rheumatol
, vol.31
, pp. 169-174
-
-
Larocca, C.A.1
-
204
-
-
84876413465
-
Yebra Bango M. (2013) [Schnitzler’s syndrome: A case report and literature review of the response to treatment with anakinra]. Med
-
Benitez Gutierrez L, Mellor Pita S, Tutor de Ureta P, Yebra Bango M. (2013) [Schnitzler’s syndrome: a case report and literature review of the response to treatment with anakinra]. Med. Clin. (Barc.) 140:427–8.
-
Clin. (Barc.)
, vol.140
, pp. 427-428
-
-
Benitez Gutierrez, L.1
Mellor Pita, S.2
De Tutor Ureta, P.3
-
205
-
-
84884919635
-
Schnitzler syndrome: An under-diagnosed clinical entity
-
Jain T, Offord CP, Kyle RA, Dingli D. (2013) Schnitzler syndrome: an under-diagnosed clinical entity. Haematologica. 98:1581–5.
-
(2013)
Haematologica
, vol.98
, pp. 1581-1585
-
-
Jain, T.1
Offord, C.P.2
Kyle, R.A.3
Dingli, D.4
-
206
-
-
84876685876
-
Schnitzler’s syndrome: Diagnosis, treatment, and follow-up
-
Simon A, et al. (2013) Schnitzler’s syndrome: diagnosis, treatment, and follow-up. Allergy. 68:562–8.
-
(2013)
Allergy
, vol.68
, pp. 562-568
-
-
Simon, A.1
-
207
-
-
84875098839
-
Effect of in vitro and in vivo anakinra on cytokines production in Schnitzler syndrome
-
Launay D, et al. (2013) Effect of in vitro and in vivo anakinra on cytokines production in Schnitzler syndrome. PLoS One. 8:e59327.
-
(2013)
Plos One
, pp. 8
-
-
Launay, D.1
-
208
-
-
84863430275
-
Dermal interleukin-1 expression and effective and long-lasting therapy with interleukin- 1 receptor antagonist anakinra in Schnitzler syndrome. Acta. Derm
-
Volz T, et al. (2012) Dermal interleukin-1 expression and effective and long-lasting therapy with interleukin- 1 receptor antagonist anakinra in Schnitzler syndrome. Acta. Derm. Venereol. 92:393–4.
-
(2012)
Venereol
, vol.92
, pp. 393-394
-
-
Volz, T.1
-
209
-
-
42749091765
-
Antisynthetase syndrome with refractory polyarthritis and fever successfully treated with the IL-1 receptor antagonist, anakinra: A case report
-
Furlan A, Botsios C, Ruffatti A, Todesco S, Punzi L. (2008) Antisynthetase syndrome with refractory polyarthritis and fever successfully treated with the IL-1 receptor antagonist, anakinra: a case report. Joint Bone Spine. 75:366–7.
-
(2008)
Joint Bone Spine
, vol.75
, pp. 366-367
-
-
Furlan, A.1
Botsios, C.2
Ruffatti, A.3
Todesco, S.4
Punzi, L.5
-
210
-
-
84898847548
-
Current and future treatments for Behcet’s uveitis: Road to remission
-
Mesquida M, et al. (2014) Current and future treatments for Behcet’s uveitis: road to remission. Int. Ophthalmol. 34:365–81.
-
(2014)
Int. Ophthalmol
, vol.34
, pp. 365-381
-
-
Mesquida, M.1
-
211
-
-
79953677480
-
Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle- Wells syndrome
-
Kuemmerle-Deschner JB, et al. (2011) Efficacy and safety of anakinra therapy in pediatric and adult patients with the autoinflammatory Muckle- Wells syndrome. Arthritis Rheum. 63:840–9.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 840-849
-
-
Kuemmerle-Deschner, J.B.1
-
212
-
-
33845686908
-
Phenotype, genotype, and sustained response to anakinra in 22 patients with autoinflammatory disease associated with CIAS-1/NALP3 mutations. Arch
-
Leslie KS, et al. (2006) Phenotype, genotype, and sustained response to anakinra in 22 patients with autoinflammatory disease associated with CIAS-1/NALP3 mutations. Arch. Dermatol. 142:1591–7.
-
(2006)
Dermatol
, vol.142
, pp. 1591-1597
-
-
Leslie, K.S.1
-
213
-
-
33847364065
-
Successful treatment of renal amyloidosis due to familial cold autoinflammatory syndrome using an interleukin 1 receptor antagonist
-
Thornton BD, Hoffman HM, Bhat A, Don BR. (2007) Successful treatment of renal amyloidosis due to familial cold autoinflammatory syndrome using an interleukin 1 receptor antagonist. Am. J. Kidney Dis. 49:477–81.
-
(2007)
Am. J. Kidney Dis
, vol.49
, pp. 477-481
-
-
Thornton, B.D.1
Hoffman, H.M.2
Bhat, A.3
Don, B.R.4
-
214
-
-
78649907431
-
Anakinra efficacy in a Caucasian patient with renal AA amyloidosis secondary to cryopyrin-associated periodic syndrome
-
Ait-Abdesselam T, et al. (2011) Anakinra efficacy in a Caucasian patient with renal AA amyloidosis secondary to cryopyrin-associated periodic syndrome. Joint Bone Spine. 77:616–7.
-
(2011)
Joint Bone Spine
, vol.77
, pp. 616-617
-
-
Ait-Abdesselam, T.1
-
215
-
-
80051489634
-
Partial response to anakinra in life-threatening Henoch-Schonlein purpura: Case report. Pediatr. Rheumatol
-
Boyer EM, Turman M, O’Neil KM. (2011) Partial response to anakinra in life-threatening Henoch-Schonlein purpura: case report. Pediatr. Rheumatol. Online J. 9:21.
-
(2011)
Online J
, vol.9
, pp. 21
-
-
Boyer, E.M.1
Turman, M.2
O’neil, K.M.3
-
216
-
-
58249112751
-
Successful treatment of idiopathic recurrent pericarditis in children with interleukin-1beta receptor antagonist (Anakinra): An unrecognized autoinflammatory disease?
-
Picco P, et al. (2009) Successful treatment of idiopathic recurrent pericarditis in children with interleukin-1beta receptor antagonist (anakinra): an unrecognized autoinflammatory disease? Arthritis Rheum. 60:264–8.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 264-268
-
-
Picco, P.1
-
217
-
-
81155159706
-
A case series and systematic literature review of anakinra and immunosuppression in idiopathic recurrent pericarditis
-
Scott IC, Vijay Hajela V, Hawkins PN, Lachmann HJ. (2011) A case series and systematic literature review of anakinra and immunosuppression in idiopathic recurrent pericarditis. J. Cardiol. Cases. 4: e93–7.
-
(2011)
J. Cardiol. Cases
, vol.4
-
-
Scott, I.C.1
Vijay Hajela, V.2
Hawkins, P.N.3
Lachmann, H.J.4
-
218
-
-
84889559984
-
Efficacy of an interleukin-1beta receptor antagonist (Anakinra) in idiopathic recurrent pericarditis. Pediatr
-
Scardapane A, Brucato A, Chiarelli F, Breda L. (2013) Efficacy of an interleukin-1beta receptor antagonist (anakinra) in idiopathic recurrent pericarditis. Pediatr. Cardiol. 34:1989–91.
-
(2013)
Cardiol
, vol.34
, pp. 1989-1991
-
-
Scardapane, A.1
Brucato, A.2
Chiarelli, F.3
Breda, L.4
-
219
-
-
84877793412
-
Pericardial syndromes: An update after the ESC guidelines 2004
-
Seferovic PM, et al. (2013) Pericardial syndromes: an update after the ESC guidelines 2004. Heart Failure Rev. 18:255–66.
-
(2013)
Heart Failure Rev
, vol.18
, pp. 255-266
-
-
Seferovic, P.M.1
-
220
-
-
84878017319
-
Successful treatment of idiopathic recurrent pericarditis with interleukin-1 receptor antagonist (Anakinra). Pediatr
-
Camacho-Lovillo M, Mendez-Santos A. (2013) Successful treatment of idiopathic recurrent pericarditis with interleukin-1 receptor antagonist (Anakinra). Pediatr. Cardiol. 34:1293–94.
-
(2013)
Cardiol
, vol.34
, pp. 1293-1294
-
-
Camacho-Lovillo, M.1
Mendez-Santos, A.2
-
221
-
-
33646526373
-
Functional outcomes of treatment of neonatal onset multisystem inflammatory disease (NOMID) with anakina. Arthr
-
Paul SM, et al. (2005) Functional outcomes of treatment of neonatal onset multisystem inflammatory disease (NOMID) with anakina. Arthr. Rheumat. 52 Suppl:S536.
-
(2005)
Rheumat. 52 Suppl
, pp. S536
-
-
Paul, S.M.1
-
222
-
-
43949116263
-
The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis
-
Gattorno M, et al. (2008) The pattern of response to anti-interleukin-1 treatment distinguishes two subsets of patients with systemic-onset juvenile idiopathic arthritis. Arthritis Rheum. 58:1505–15.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1505-1515
-
-
Gattorno, M.1
-
223
-
-
79551654446
-
Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: Report of forty-six patients from an international multicenter series
-
Nigrovic PA, et al. (2011) Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: report of forty-six patients from an international multicenter series. Arthritis Rheum. 63:545–55.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 545-555
-
-
Nigrovic, P.A.1
-
224
-
-
84863428204
-
Consensus treatment plans for new-onset systemic juvenile idiopathic arthritis. Arthritis Care Res
-
DeWitt EM, et al. (2012) Consensus treatment plans for new-onset systemic juvenile idiopathic arthritis. Arthritis Care Res. (Hoboken). 64:1001–10.
-
(2012)
(Hoboken).
, vol.64
, pp. 1001-1010
-
-
Dewitt, E.M.1
-
225
-
-
20044390451
-
Prompt response to treatment with anakinra in adult onset Still’s disease
-
Aelion JA, Odhav SK. (2004) Prompt response to treatment with anakinra in adult onset Still’s disease. Ann. Rheum. Dis. 63 Suppl 1:265.
-
(2004)
Ann. Rheum. Dis. 63 Suppl
, vol.1
, pp. 265
-
-
Aelion, J.A.1
Odhav, S.K.2
-
227
-
-
34547878809
-
Anakinra in patients with treatment-resistant adult-onset Still’s disease: Four case reports with serial cytokine measurements and a review of the literature. Semin
-
Kotter I, et al. (2007) Anakinra in patients with treatment-resistant adult-onset Still’s disease: four case reports with serial cytokine measurements and a review of the literature. Semin. Arthritis Rheum. 37:189–97.
-
(2007)
Arthritis Rheum
, vol.37
, pp. 189-197
-
-
Kotter, I.1
-
228
-
-
77955365745
-
A case of refractory adult-onset Still’s disease treated with anakinra
-
Lahiri M, Teng GG. (2010) A case of refractory adult-onset Still’s disease treated with anakinra. Int. J. Rheum. Dis. 13:e36–41.
-
(2010)
Int. J. Rheum. Dis
, vol.13
-
-
Lahiri, M.1
Teng, G.G.2
-
229
-
-
39549109506
-
Interleukin-1 receptor antagonist (Anakinra) treatment in patients with systemic-onset juvenile idiopathic arthritis or adult onset Still disease: Preliminary experience in France
-
Lequerre T, et al. (2008) Interleukin-1 receptor antagonist (anakinra) treatment in patients with systemic-onset juvenile idiopathic arthritis or adult onset Still disease: preliminary experience in France. Ann. Rheum. Dis. 67:302–8.
-
(2008)
Ann. Rheum. Dis
, vol.67
, pp. 302-308
-
-
Lequerre, T.1
-
230
-
-
79952110726
-
May anakinra be used earlier in adult onset Still disease? Clin
-
Moulis G, Sailler L, Astudillo L, Pugnet G, Arlet P. (2010) May anakinra be used earlier in adult onset Still disease? Clin. Rheumatol. 29:1199–200.
-
(2010)
Rheumatol
, vol.29
, pp. 1199-1200
-
-
Moulis, G.1
Sailler, L.2
Astudillo, L.3
Pugnet, G.4
Arlet, P.5
-
231
-
-
41849091141
-
Acute hepatitis in adult Still’s disease during corticosteroid treatment successfully treated with anakinra. Clin
-
Mylona E, et al. (2008) Acute hepatitis in adult Still’s disease during corticosteroid treatment successfully treated with anakinra. Clin. Rheumatol. 27:659–61.
-
(2008)
Rheumatol
, vol.27
, pp. 659-661
-
-
Mylona, E.1
-
232
-
-
75749100258
-
IL1-receptor antagonist anakinra provides long-lasting efficacy in the treatment of refractory adult-onset Still’s disease
-
Naumann L, et al. (2010) IL1-receptor antagonist anakinra provides long-lasting efficacy in the treatment of refractory adult-onset Still’s disease. Ann. Rheum. Dis. 69:466–7.
-
(2010)
Ann. Rheum. Dis
, vol.69
, pp. 466-467
-
-
Naumann, L.1
-
233
-
-
78651110738
-
Adult-onset Still’s disease with myocarditis successfully treated with the interleukin-1 receptor antagonist anakinra
-
Raffeiner B, et al. (2011) Adult-onset Still’s disease with myocarditis successfully treated with the interleukin-1 receptor antagonist anakinra. Joint Bone Spine. 78:100–1.
-
(2011)
Joint Bone Spine
, vol.78
, pp. 100-101
-
-
Raffeiner, B.1
-
234
-
-
0141992897
-
Successful treatment of a patient with refractory adultonset Still’s disease with anakinra
-
Rudinskaya A, Trock DH. (2003) Successful treatment of a patient with refractory adultonset Still’s disease with anakinra. J. Clin. Rheumatol. 9:330–2.
-
(2003)
J. Clin. Rheumatol
, vol.9
, pp. 330-332
-
-
Rudinskaya, A.1
Trock, D.H.2
-
235
-
-
77954921217
-
Marked effect and steroid-sparing ability of anakinra on a patient with refractory adult-onset Still’s disease. Mod
-
Tamaki H, et al. (2010) Marked effect and steroid-sparing ability of anakinra on a patient with refractory adult-onset Still’s disease. Mod. Rheumatol. 20:200–4.
-
(2010)
Rheumatol
, vol.20
, pp. 200-204
-
-
Tamaki, H.1
-
237
-
-
61449170183
-
Continuation of anakinra despite the development of a pruritic rash in an otherwise refractory case of adultonset Still’s disease
-
Vordenbaumen S, Ostendorf B, Sander O, Richter J, Schneider M. (2009) Continuation of anakinra despite the development of a pruritic rash in an otherwise refractory case of adultonset Still’s disease. Ann. Rheum. Dis. 68:450–1.
-
(2009)
Ann. Rheum. Dis
, vol.68
, pp. 450-451
-
-
Vordenbaumen, S.1
Ostendorf, B.2
Sander, O.3
Richter, J.4
Schneider, M.5
-
238
-
-
57349101775
-
Blockade of interleukin 1 receptor in Still’s disease affects activation of peripheral T-lymphocytes
-
Youssef J, Lazaro E, Blanco P, Viallard JF. (2008) Blockade of interleukin 1 receptor in Still’s disease affects activation of peripheral T-lymphocytes. J. Rheumatol. 35:2453–6.
-
(2008)
J. Rheumatol
, vol.35
, pp. 2453-2456
-
-
Youssef, J.1
Lazaro, E.2
Blanco, P.3
Viallard, J.F.4
-
239
-
-
39549120448
-
Anakinra treatment for systemic juvenile idiopathic arthritis and adult onset Still disease
-
Woo P. (2008) Anakinra treatment for systemic juvenile idiopathic arthritis and adult onset Still disease. Ann. Rheum. Dis. 67:281–2.
-
(2008)
Ann. Rheum. Dis
, vol.67
, pp. 281-282
-
-
Woo, P.1
-
240
-
-
71549151629
-
Adult-onset Still’s disease with liver failure requiring liver transplantation. Gastroenterol
-
Teran A, et al. (2009) Adult-onset Still’s disease with liver failure requiring liver transplantation. Gastroenterol. Hepatol. 32:681–6.
-
(2009)
Hepatol
, vol.32
, pp. 681-686
-
-
Teran, A.1
-
242
-
-
84922588111
-
Adultonset Still’s disease masquerading as sepsis in an asplenic active duty soldier. Case Rep
-
Jaqua NT, Finger D, Hawley JS. (2012) Adultonset Still’s disease masquerading as sepsis in an asplenic active duty soldier. Case Rep. Med. 2012:349521.
-
(2012)
Med
, pp. 349-521
-
-
Jaqua, N.T.1
Finger, D.2
Hawley, J.S.3
-
243
-
-
84876744340
-
Anakinra in adultonset Still’s disease: Long-term treatment in patients resistant to conventional therapy
-
Giampietro C, et al. (2013) Anakinra in adultonset Still’s disease: long-term treatment in patients resistant to conventional therapy. Arthritis Care Res. 65:822–6.
-
(2013)
Arthritis Care Res
, vol.65
, pp. 822-826
-
-
Giampietro, C.1
-
244
-
-
33749994238
-
Interleukin 1 receptor antagonist to treat cytophagic histiocytic panniculitis with secondary hemophagocytic lymphohistiocytosis
-
Behrens EM, Kreiger PA, Cherian S, Cron RQ. (2006) Interleukin 1 receptor antagonist to treat cytophagic histiocytic panniculitis with secondary hemophagocytic lymphohistiocytosis. J. Rheumatol. 33:2081–4.
-
(2006)
J. Rheumatol
, vol.33
, pp. 2081-2084
-
-
Behrens, E.M.1
Kreiger, P.A.2
Cherian, S.3
Cron, R.Q.4
-
245
-
-
77955028074
-
Cytophagic histiocytic panniculitis and hemophagocytic lymphohistiocytosis: An overview. Dermatol
-
Aronson IK, Worobec SM. (2010) Cytophagic histiocytic panniculitis and hemophagocytic lymphohistiocytosis: an overview. Dermatol. Ther. 23:389–402.
-
(2010)
Ther
, vol.23
, pp. 389-402
-
-
Aronson, I.K.1
Worobec, S.M.2
-
246
-
-
74549215677
-
A 36-year-old woman with recurrent high-grade fevers, hypotension, and hypertriglyceridemia
-
Chou RC, Dinarello CA, Ferry JA, Dal Cin P. (2010) A 36-year-old woman with recurrent high-grade fevers, hypotension, and hypertriglyceridemia. Arthritis Care Res. 62:137–40.
-
(2010)
Arthritis Care Res
, vol.62
, pp. 137-140
-
-
Chou, R.C.1
Dinarello, C.A.2
Ferry, J.A.3
Dal Cin, P.4
-
247
-
-
84883248433
-
Successful immunotherapy in life-threatening parvovirus
-
Butin M, et al. (2013) Successful immunotherapy in life-threatening parvovirus B19 infection in a child. Pediatr. Infect. Dis. J. 32:789–92.
-
(2013)
B19 Infection in a Child. Pediatr. Infect. Dis. J
, vol.32
, pp. 789-792
-
-
Butin, M.1
-
248
-
-
38749150377
-
Efficacy of anakinra, an IL1 receptor antagonist, in refractory Sweet syndrome
-
Delluc A, et al. (2008) Efficacy of anakinra, an IL1 receptor antagonist, in refractory Sweet syndrome. Ann. Rheum. Dis. 67:278–9.
-
(2008)
Ann. Rheum. Dis
, vol.67
, pp. 278-279
-
-
Delluc, A.1
-
249
-
-
79955685806
-
Efficacy of anti-interleukin-1 receptor antagonist anakinra (Kineret(R)) in a case of refractory Sweet’s syndrome
-
Kluger N, Gil-Bistes D, Guillot B, Bessis D. (2011) Efficacy of anti-interleukin-1 receptor antagonist anakinra (Kineret(R)) in a case of refractory Sweet’s syndrome. Dermatology. 222:123–7.
-
(2011)
Dermatology
, vol.222
, pp. 123-127
-
-
Kluger, N.1
Gil-Bistes, D.2
Guillot, B.3
Bessis, D.4
-
250
-
-
84876820068
-
Neutrophilic urticaria with systemic inflammation: A case series
-
Belani H, et al. (2013) Neutrophilic urticaria with systemic inflammation: a case series. JAMA Dermatol. 149:453–8.
-
(2013)
JAMA Dermatol
, vol.149
, pp. 453-458
-
-
Belani, H.1
-
251
-
-
77951877587
-
Anakinra for difficult-to-treat neutrophilic panniculitis: IL-1 blockade as a promising treatment option for neutrophil-mediated inflammatory skin disease
-
Lipsker D, Perrigouard C, Foubert A, Cribier B. (2010) Anakinra for difficult-to-treat neutrophilic panniculitis: IL-1 blockade as a promising treatment option for neutrophil-mediated inflammatory skin disease. Dermatology. 220:264–7.
-
(2010)
Dermatology
, vol.220
, pp. 264-267
-
-
Lipsker, D.1
Perrigouard, C.2
Foubert, A.3
Cribier, B.4
-
252
-
-
78549269492
-
Rationale and efficacy of interleukin-1 targeting in Erdheim-Chester disease
-
Aouba A, et al. (2010) Rationale and efficacy of interleukin-1 targeting in Erdheim-Chester disease. Blood. 116:4070–6.
-
(2010)
Blood
, vol.116
, pp. 4070-4076
-
-
Aouba, A.1
-
253
-
-
84898547836
-
Successful treatment of Erdheim-Chester disease by interleukin-1 receptor antagonist protein
-
Courcoul A, Vignot E, Chapurlat R. (2014) Successful treatment of Erdheim-Chester disease by interleukin-1 receptor antagonist protein. Joint Bone Spine. 81:175–7.
-
(2014)
Joint Bone Spine
, vol.81
, pp. 175-177
-
-
Courcoul, A.1
Vignot, E.2
Chapurlat, R.3
-
254
-
-
84875521991
-
Favorable radiological outcome of skeletal Erdheim-Chester disease involvement with anakinra
-
Aubert O, et al. (2013) Favorable radiological outcome of skeletal Erdheim-Chester disease involvement with anakinra. Joint Bone Spine. 80:206–7.
-
(2013)
Joint Bone Spine
, vol.80
, pp. 206-207
-
-
Aubert, O.1
-
255
-
-
77954222687
-
Dysregulation of P2X7 receptor- inflammasome axis in SAPHO syndrome: Successful treatment with anakinra
-
Colina M, et al. (2010) Dysregulation of P2X7 receptor- inflammasome axis in SAPHO syndrome: successful treatment with anakinra. Rheumatology (Oxford). 49:1416–8.
-
(2010)
Rheumatology (Oxford)
, vol.49
, pp. 1416-1418
-
-
Colina, M.1
-
256
-
-
77954735316
-
Biologic therapy in refractory chronic non-bacterial osteomyelitis of childhood
-
Eleftheriou D, et al. (2011) Biologic therapy in refractory chronic non-bacterial osteomyelitis of childhood. Rheumatology (Oxford). 49:1505–12.
-
(2011)
Rheumatology (Oxford)
, vol.49
, pp. 1505-1512
-
-
Eleftheriou, D.1
-
257
-
-
84860919264
-
Anakinra treatment of SAPHO syndrome: Short-term results of an open study
-
Wendling D, Prati C, Aubin F. (2012) Anakinra treatment of SAPHO syndrome: short-term results of an open study. Ann. Rheum. Dis. 71:1098–1100.
-
(2012)
Ann. Rheum. Dis
, vol.71
, pp. 1098-1100
-
-
Wendling, D.1
Prati, C.2
Aubin, F.3
-
258
-
-
79955147587
-
Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) is a disorder of innate immunity and Th1 activation responsive to IL-1 blockade
-
Stojanov S, et al. (2011) Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) is a disorder of innate immunity and Th1 activation responsive to IL-1 blockade. Proc. Natl. Acad. Sci. U. S. A. 108:7148–53.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A
, vol.108
, pp. 7148-7153
-
-
Stojanov, S.1
-
259
-
-
84872270071
-
Typical and severe tumor necrosis factor receptor-associated periodic syndrome in the absence of mutations in the TNFRSF1A gene: A case series. Rheumatol
-
Cantarini L, et al. (2012) Typical and severe tumor necrosis factor receptor-associated periodic syndrome in the absence of mutations in the TNFRSF1A gene: a case series. Rheumatol. Int. 32:4015–8.
-
(2012)
Int
, vol.32
, pp. 4015-4018
-
-
Cantarini, L.1
-
260
-
-
59149104498
-
IL-1RA agonist (Anakinra) in the treatment of multifocal Castleman disease
-
Galeotti C, et al. (2008) IL-1RA agonist (anakinra) in the treatment of multifocal Castleman disease. J. Pediatr. Hematol. Oncol. 30:920–4.
-
(2008)
J. Pediatr. Hematol. Oncol
, vol.30
, pp. 920-924
-
-
Galeotti, C.1
-
261
-
-
79954428209
-
Jessner-Kanof disease induced by leflunomide: A dermal variant of cutaneous lupus? Rheumatol
-
Sparsa L, et al. (2012) Jessner-Kanof disease induced by leflunomide: a dermal variant of cutaneous lupus? Rheumatol. Int. 31:255–8.
-
(2012)
Int
, vol.31
, pp. 255-258
-
-
Sparsa, L.1
-
262
-
-
84868454230
-
A child with severe relapsing Kawasaki disease rescued by IL-1 receptor blockade and extracorporeal membrane oxygenation
-
Cohen S, et al. (2012) A child with severe relapsing Kawasaki disease rescued by IL-1 receptor blockade and extracorporeal membrane oxygenation. Ann. Rheum. Dis. 71:2059–61.
-
(2012)
Ann. Rheum. Dis
, vol.71
, pp. 2059-2061
-
-
Cohen, S.1
-
264
-
-
84895819096
-
IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans
-
de Luca A, et al. (2014) IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans. Proc. Natl. Acad. Sci. U. S. A. 111:3526–31.
-
(2014)
Proc. Natl. Acad. Sci. U. S. A
, vol.111
, pp. 3526-3531
-
-
De Luca, A.1
-
265
-
-
84892672645
-
An open-label study of anakinra for the treatment of moderate to severe hidradenitis suppurativa
-
Leslie KS, Tripathi SV, Nguyen TV, Pauli M, Rosenblum MD. (2014) An open-label study of anakinra for the treatment of moderate to severe hidradenitis suppurativa. J. Am. Acad. Dermatol. 70:243–51.
-
(2014)
J. Am. Acad. Dermatol
, vol.70
, pp. 243-251
-
-
Leslie, K.S.1
Tripathi, S.V.2
Nguyen, T.V.3
Pauli, M.4
Rosenblum, M.D.5
-
266
-
-
84899899588
-
Recombinant human interleukin- 1 receptor antagonist in severe traumatic brain injury: A phase II randomized control trial
-
Helmy A, et al. (2014) Recombinant human interleukin- 1 receptor antagonist in severe traumatic brain injury: a phase II randomized control trial. J. Cereb. Blood Flow Metab. 34:845–51.
-
(2014)
J. Cereb. Blood Flow Metab
, vol.34
, pp. 845-851
-
-
Helmy, A.1
-
267
-
-
0036735138
-
Blocking the effects of IL-1 in rheumatoid arthritis protects bone and cartilage
-
Abramson SB, Amin A. (2002) Blocking the effects of IL-1 in rheumatoid arthritis protects bone and cartilage. Rheumatology (Oxford). 41:972–80.
-
(2002)
Rheumatology (Oxford)
, vol.41
, pp. 972-980
-
-
Abramson, S.B.1
Amin, A.2
-
269
-
-
17444394445
-
Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist
-
Bresnihan B, et al. (1998) Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist. Arthritis Rheum. 41:2196–204.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 2196-2204
-
-
Bresnihan, B.1
-
270
-
-
34447272928
-
Anakinra, a recombinant human IL-1 receptor antagonist, in clinical practice:Outcome in 60 patients with severe rheumatoid arthritis
-
Botsios C, et al. (2007) Anakinra, a recombinant human IL-1 receptor antagonist, in clinical practice: outcome in 60 patients with severe rheumatoid arthritis. Reumatismo. 59:32–7.
-
(2007)
Reumatismo
, vol.59
, pp. 32-37
-
-
Botsios, C.1
-
271
-
-
78650834275
-
Biologics for rheumatoid arthritis: An overview of
-
Singh JA, et al. (2010) Biologics for rheumatoid arthritis: an overview of Cochrane reviews. Sao Paulo Med. J. 128:309–10.
-
(2010)
Cochrane Reviews. Sao Paulo Med. J
, vol.128
, pp. 309-310
-
-
Singh, J.A.1
-
272
-
-
79959712981
-
Secondary failure to treatment with recombinant human IL-1 receptor antagonist in Chinese patients with rheumatoid arthritis. Clin
-
Bao J, et al. (2011) Secondary failure to treatment with recombinant human IL-1 receptor antagonist in Chinese patients with rheumatoid arthritis. Clin. Rheumatol. 30:697–701.
-
(2011)
Rheumatol
, vol.30
, pp. 697-701
-
-
Bao, J.1
-
273
-
-
0000931093
-
Anakinra reduces the rate of joint destruction after 1 year of treatment in a randomized controlled cohort of patients with rheumatoid arthritis
-
Bresnihan B, Newmark RD, Robbins S, Mc- Cabe DP, Genant HK. (2000) Anakinra reduces the rate of joint destruction after 1 year of treatment in a randomized controlled cohort of patients with rheumatoid arthritis. Arthrit. Rheum. 43 Suppl S9-S289.
-
(2000)
Arthrit. Rheum
, vol.43
, pp. SS9-S289
-
-
Bresnihan, B.1
Newmark, R.D.2
Robbins, S.3
Mc-Cabe, D.P.4
Genant, H.K.5
-
274
-
-
2642550601
-
Effects of anakinra monotherapy on joint damage in patients with rheumatoid arthritis: Extension of a 24-week randomized, placebocontrolled trial
-
Bresnihan B, Newmark R, Robbins S, Genant HK. (2004) Effects of anakinra monotherapy on joint damage in patients with rheumatoid arthritis: extension of a 24-week randomized, placebocontrolled trial. J. Rheumatol. 31:1103–11.
-
(2004)
J. Rheumatol
, vol.31
, pp. 1103-1111
-
-
Bresnihan, B.1
Newmark, R.2
Robbins, S.3
Genant, H.K.4
-
275
-
-
0034083128
-
A multicenter, double-blind, dose-ranging, randomized, placebo-controlled study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis: Radiologic progression and correlation of Genant and Larsen scores
-
Jiang Y, et al. (2000) A multicenter, double-blind, dose-ranging, randomized, placebo-controlled study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis: radiologic progression and correlation of Genant and Larsen scores. Arthritis Rheum. 43:1001–9.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 1001-1009
-
-
Jiang, Y.1
-
276
-
-
78650222628
-
Treatment with anakinra reduces the rate of joint destruction and shows accelerated benefit in the second 6 months of treatment for patients with rheumatoid arthritis
-
Genant HK, et al. (2001) Treatment with anakinra reduces the rate of joint destruction and shows accelerated benefit in the second 6 months of treatment for patients with rheumatoid arthritis. Ann. Rheumat. Dis. 40 Suppl 1:169.
-
(2001)
Ann. Rheumat. Dis
, vol.40
, Issue.1
, pp. 169
-
-
Genant, H.K.1
-
277
-
-
0035144287
-
The effects of treatment with interleukin-1 receptor antagonist on the inflamed synovial membrane in rheumatoid arthritis
-
Cunnane G, Madigan A, Murphy E, FitzGerald O, Bresnihan B. (2001) The effects of treatment with interleukin-1 receptor antagonist on the inflamed synovial membrane in rheumatoid arthritis. Rheumatology (Oxford). 40:62–9.
-
(2001)
Rheumatology (Oxford)
, vol.40
, pp. 62-69
-
-
Cunnane, G.1
Madigan, A.2
Murphy, E.3
Fitzgerald, O.4
Bresnihan, B.5
-
278
-
-
78650747686
-
Effectiveness of biologic therapies for rheumatoid arthritis: An indirect comparisons approach
-
Devine EB, Alfonso-Cristancho R, Sullivan SD. (2011) Effectiveness of biologic therapies for rheumatoid arthritis: an indirect comparisons approach. Pharmacotherapy. 31:39–51.
-
(2011)
Pharmacotherapy
, vol.31
, pp. 39-51
-
-
Devine, E.B.1
Alfonso-Cristancho, R.2
Sullivan, S.D.3
-
279
-
-
79955567265
-
Circulating Dickkopf-1 is correlated with bone erosion and inflammation in rheumatoid arthritis
-
Wang SY, et al. (2011) Circulating Dickkopf-1 is correlated with bone erosion and inflammation in rheumatoid arthritis. J. Rheumatol. 38:821–7.
-
(2011)
J. Rheumatol
, vol.38
, pp. 821-827
-
-
Wang, S.Y.1
-
280
-
-
80052977037
-
A mixed treatment comparison of the short-term efficacy of biologic disease modifying anti-rheumatic drugs in established rheumatoid arthritis
-
Turkstra E, Ng SK, Scuffham PA. (2011) A mixed treatment comparison of the short-term efficacy of biologic disease modifying anti-rheumatic drugs in established rheumatoid arthritis. Curr. Med. Res. Opin. 27:1885–97.
-
(2011)
Curr. Med. Res. Opin
, vol.27
, pp. 1885-1897
-
-
Turkstra, E.1
Ng, S.K.2
Scuffham, P.A.3
-
281
-
-
34447318083
-
The efficacy of inhibiting tumour necrosis factor alpha and interleukin 1 in patients with rheumatoid arthritis: A meta-analysis and adjusted indirect comparisons
-
Nixon R, Bansback N, Brennan A. (2007) The efficacy of inhibiting tumour necrosis factor alpha and interleukin 1 in patients with rheumatoid arthritis: a meta-analysis and adjusted indirect comparisons. Rheumatology (Oxford). 46:1140–7.
-
(2007)
Rheumatology (Oxford)
, vol.46
, pp. 1140-1147
-
-
Nixon, R.1
Bansback, N.2
Brennan, A.3
-
282
-
-
3042663309
-
Patient- versus physician-reported outcomes in rheumatoid arthritis patients treated with recombinant interleukin-1 receptor antagonist (Anakinra) therapy
-
Cohen SB, Strand V, Aguilar D, Ofman JJ. (2004) Patient- versus physician-reported outcomes in rheumatoid arthritis patients treated with recombinant interleukin-1 receptor antagonist (anakinra) therapy. Rheumatology (Oxford). 43:704–11.
-
(2004)
Rheumatology (Oxford)
, vol.43
, pp. 704-711
-
-
Cohen, S.B.1
Strand, V.2
Aguilar, D.3
Ofman, J.J.4
-
283
-
-
2542478922
-
The use of anakinra, an interleukin- 1 receptor antagonist, in the treatment of rheumatoid arthritis
-
Cohen SB. (2004) The use of anakinra, an interleukin- 1 receptor antagonist, in the treatment of rheumatoid arthritis. Rheum. Dis. Clin. North. Am. 30:365–80.
-
(2004)
Rheum. Dis. Clin. North. Am
, vol.30
, pp. 365-380
-
-
Cohen, S.B.1
-
284
-
-
33745052684
-
Anakinra (Interleukin-1 receptor antagonist) has positive effects on function and quality of life in patients with rheumatoid arthritis. Adv
-
Kavanaugh A. (2006) Anakinra (interleukin-1 receptor antagonist) has positive effects on function and quality of life in patients with rheumatoid arthritis. Adv. Ther. 23:208–17.
-
(2006)
Ther
, vol.23
, pp. 208-217
-
-
Kavanaugh, A.1
-
285
-
-
0037309790
-
Interleukin 1 receptor antagonist anakinra improves functional status in patients with rheumatoid arthritis
-
Cohen SB, Woolley JM, Chan W. (2003) Interleukin 1 receptor antagonist anakinra improves functional status in patients with rheumatoid arthritis. J. Rheumatol. 30:225–31.
-
(2003)
J. Rheumatol
, vol.30
, pp. 225-231
-
-
Cohen, S.B.1
Woolley, J.M.2
Chan, W.3
-
286
-
-
3442885115
-
A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate
-
Cohen SB, et al. (2004) A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate. Ann. Rheum. Dis. 63:1062–8.
-
(2004)
Ann. Rheum. Dis
, vol.63
, pp. 1062-1068
-
-
Cohen, S.B.1
-
287
-
-
0037389680
-
Anakinra, a recombinant human interleukin-1 receptor antagonist (R-metHuIL-1ra), in patients with rheumatoid arthritis: A large, international, multicenter, placebo- controlled trial
-
Fleischmann RM, et al. (2003) Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis: a large, international, multicenter, placebo- controlled trial. Arthritis Rheum. 48:927–34.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 927-934
-
-
Fleischmann, R.M.1
-
288
-
-
84922564119
-
Comparative efficacy of biologics as monotherapy and in combination with methotrexate on patient reported outcomes (PROs) in rheumatoid arthritis patients with an inadequate response to conventional DMARDs: A systematic review and network meta-analysis. Health Qual
-
Jansen JP, Buckley F, Dejonckheere F, Ogale S. (2014) Comparative efficacy of biologics as monotherapy and in combination with methotrexate on patient reported outcomes (PROs) in rheumatoid arthritis patients with an inadequate response to conventional DMARDs: a systematic review and network meta-analysis. Health Qual. Life Outcomes. 12:102.
-
(2014)
Life Outcomes
, vol.12
, pp. 102
-
-
Jansen, J.P.1
Buckley, F.2
Dejonckheere, F.3
Ogale, S.4
-
289
-
-
79251552814
-
Change in CD3 positive T-cell expression in psoriatic arthritis synovium correlates with change in DAS28 and magnetic resonance imaging synovitis scores following initiation of biologic therapy: A single centre, open-label study. Arthritis Res
-
Pontifex EK, et al. (2011) Change in CD3 positive T-cell expression in psoriatic arthritis synovium correlates with change in DAS28 and magnetic resonance imaging synovitis scores following initiation of biologic therapy: a single centre, open-label study. Arthritis Res. Ther. 13:R7.
-
(2011)
Ther
, vol.13
, pp. R7
-
-
Pontifex, E.K.1
-
290
-
-
79952113703
-
An open-label pilot study of the efficacy and safety of anakinra in patients with psoriatic arthritis refractory to or intolerant of methotrexate (MTX). Clin
-
Jung N, et al. (2011) An open-label pilot study of the efficacy and safety of anakinra in patients with psoriatic arthritis refractory to or intolerant of methotrexate (MTX). Clin. Rheumatol. 29:1169–73.
-
(2011)
Rheumatol
, vol.29
, pp. 1169-1173
-
-
Jung, N.1
-
291
-
-
79959607962
-
Clinical benefits of intra-articular anakinra for persistent knee effusion
-
Brown C, Toth A, Magnussen R. (2011) Clinical benefits of intra-articular anakinra for persistent knee effusion. J. Knee Surg. 24:61–5.
-
(2011)
J. Knee Surg
, vol.24
, pp. 61-65
-
-
Brown, C.1
Toth, A.2
Magnussen, R.3
-
292
-
-
78651346861
-
Clinical benefits of intra-articular anakinra for arthrofibrosis
-
Brown CA, Toth AP, Magnussen B. (2011) Clinical benefits of intra-articular anakinra for arthrofibrosis. Orthopedics. 33:877.
-
(2011)
Orthopedics
, vol.33
, pp. 877
-
-
Brown, C.A.1
Toth, A.P.2
Magnussen, B.3
-
293
-
-
84858619829
-
Effects of intraarticular IL1-Ra for acute anterior cruciate ligament knee injury: A randomized controlled pilot trial (NCT00332254)
-
Kraus VB, et al. (2012) Effects of intraarticular IL1-Ra for acute anterior cruciate ligament knee injury: a randomized controlled pilot trial (NCT00332254). Osteoarthritis Cartilage. 20:271–8.
-
(2012)
Osteoarthritis Cartilage
, vol.20
, pp. 271-278
-
-
Kraus, V.B.1
-
295
-
-
77951025774
-
Relapsing polychondritis: New therapeutic strategies with biological agents. Rheumatol
-
Buonuomo PS, et al. (2011) Relapsing polychondritis: new therapeutic strategies with biological agents. Rheumatol. Int. 30:691–3.
-
(2011)
Int
, vol.30
, pp. 691-693
-
-
Buonuomo, P.S.1
-
296
-
-
33645298222
-
Refractory relapsing polychondritis: Rapid and sustained response in the treatment with an IL-1 receptor antagonist (anakinra)
-
Vounotrypidis P, Sakellariou GT, Zisopoulos D, Berberidis C. (2006) Refractory relapsing polychondritis: rapid and sustained response in the treatment with an IL-1 receptor antagonist (anakinra). Rheumatology (Oxford). 45:491–2.
-
(2006)
Rheumatology (Oxford)
, vol.45
, pp. 491-492
-
-
Vounotrypidis, P.1
Sakellariou, G.T.2
Zisopoulos, D.3
Berberidis, C.4
-
297
-
-
84922588110
-
Orbital relapsing polychondritis: A unique presentation, complication, and treatment. Ophthal
-
2014, Jul 28 [Epub ahead of print]
-
Moore GH, Rootman DB, Roybal N, Goldberg RA. (2014) Orbital relapsing polychondritis: a unique presentation, complication, and treatment. Ophthal. Plast. Reconstr. Surg. 2014, Jul 28 [Epub ahead of print].
-
(2014)
Plast. Reconstr. Surg
-
-
Moore, G.H.1
Rootman, D.B.2
Roybal, N.3
Goldberg, R.A.4
-
298
-
-
84863879273
-
Adult-onset Still’s disease and chronic recurrent multifocal osteomyelitis: A hitherto undescribed manifestation of autoinflammation. Rheumatol
-
Rech J, et al. (2012) Adult-onset Still’s disease and chronic recurrent multifocal osteomyelitis: a hitherto undescribed manifestation of autoinflammation. Rheumatol. Int. 32:1827–9.
-
(2012)
Int
, vol.32
, pp. 1827-1829
-
-
Rech, J.1
-
300
-
-
38649126902
-
Sustained response to anakinra in ankylosing spondylitis
-
Bennett AN, et al. (2008) Sustained response to anakinra in ankylosing spondylitis. Rheumatology (Oxford). 47:223–4.
-
(2008)
Rheumatology (Oxford)
, vol.47
, pp. 223-224
-
-
Bennett, A.N.1
-
301
-
-
4344699365
-
Efficacy of anakinra in active ankylosing spondylitis: A clinical and magnetic resonance imaging study
-
Tan AL, et al. (2004) Efficacy of anakinra in active ankylosing spondylitis: a clinical and magnetic resonance imaging study. Ann. Rheum. Dis. 63:1041–5.
-
(2004)
Ann. Rheum. Dis
, vol.63
, pp. 1041-1045
-
-
Tan, A.L.1
-
302
-
-
77954289997
-
Epidemiology: Gout—bad for the heart as well as the joint. Nat
-
So A. (2010) Epidemiology: gout—bad for the heart as well as the joint. Nat. Rev. Rheumatol. 6:386–7.
-
(2010)
Rev. Rheumatol
, vol.6
, pp. 386-387
-
-
So, A.1
-
303
-
-
84868193590
-
Interleukin 1beta blockade improves signs and symptoms of chronic calcium pyrophosphate crystal arthritis resistant to treatment
-
Diamantopoulos AP, Brodin C, Hetland H, Haugeberg G. (2012) Interleukin 1beta blockade improves signs and symptoms of chronic calcium pyrophosphate crystal arthritis resistant to treatment. J. Clin. Rheumatol. 18:310–11.
-
(2012)
J. Clin. Rheumatol
, vol.18
, pp. 310-311
-
-
Diamantopoulos, A.P.1
Brodin, C.2
Hetland, H.3
Haugeberg, G.4
-
304
-
-
84870699350
-
Efficacy of anakinra for refractory acute calcium pyrophosphate crystal arthritis
-
Molto A, Ea HK, Richette P, Bardin T, Liote F. (2012) Efficacy of anakinra for refractory acute calcium pyrophosphate crystal arthritis. Joint Bone Spine. 79:621–3.
-
(2012)
Joint Bone Spine
, vol.79
, pp. 621-623
-
-
Molto, A.1
Ea, H.K.2
Richette, P.3
Bardin, T.4
Liote, F.5
-
305
-
-
84875517323
-
Efficacy of anakinra in calcium pyrophosphate crystal-induced arthritis: A report of 16 cases and review of the literature
-
Ottaviani S, et al. (2013) Efficacy of anakinra in calcium pyrophosphate crystal-induced arthritis: a report of 16 cases and review of the literature. Joint Bone Spine. 80:178–82.
-
(2013)
Joint Bone Spine
, vol.80
, pp. 178-182
-
-
Ottaviani, S.1
-
306
-
-
79952011681
-
First observation of the efficacy of IL-1ra to treat tophaceous gout of the lumbar spine
-
Funck-Brentano T, et al. (2011) First observation of the efficacy of IL-1ra to treat tophaceous gout of the lumbar spine. Rheumatology (Oxford). 50:622–4.
-
(2011)
Rheumatology (Oxford)
, vol.50
, pp. 622-624
-
-
Funck-Brentano, T.1
-
307
-
-
84898005207
-
Anakinra treatment in patients with refractory inflammatory myopathies and possible predictive response biomarkers: A mechanistic study with 12 months follow-up
-
Zong M, et al. (2014) Anakinra treatment in patients with refractory inflammatory myopathies and possible predictive response biomarkers: a mechanistic study with 12 months follow-up. Ann. Rheum. Dis. 73:913–20.
-
(2014)
Ann. Rheum. Dis
, vol.73
, pp. 913-920
-
-
Zong, M.1
-
308
-
-
84875922144
-
Interleukin-1 receptor antagonist in refractory haemochromatosis-related arthritis of the hands
-
Latourte A, Frazier A, Briere C, Ea HK, Richette P. (2013) Interleukin-1 receptor antagonist in refractory haemochromatosis-related arthritis of the hands. Ann. Rheum. Dis. 72:783–4.
-
(2013)
Ann. Rheum. Dis
, vol.72
, pp. 783-784
-
-
Latourte, A.1
Frazier, A.2
Briere, C.3
Ea, H.K.4
Richette, P.5
|