NOD2 gene-associated pediatric granulomatous arthritis: Clinical diversity, novel and recurrent mutations, and evidence of clinical improvement with interleukin-1 blockade in a Spanish cohort

Arthritis and Rheumatism

Volumn 56, Issue 11, 2007, Pages 3805-3813

  Aróstegui, Juan I ^a   Arnal, Cristina ^b   Merino, Rosa ^c   Modesto, Consuelo ^b   Carballo, María Antonia ^d   Moreno, Purificación ^e   García Consuegra, Julia ^c   Naranjo, Antonio ^f   Ramos, Eduardo ^g   De Paz, Pilar ^b   Rius, Josefa ^a   Plaza, Susana ^a   Yagüe, Jordi ^a  

^a HOSPITAL CLÍNIC   (Spain)

^b HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^c HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^d HOSPITAL XERAL CALDE   (Spain)

^e HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

^f HOSPITAL UNIVERSITARIO DE GRAN CANARIA DR NEGRÍN   (Spain)

^g HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CORTICOSTEROID; CYCLOSPORIN A; CYTOKINE; ETANERCEPT; GENOMIC DNA; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; SALICYLIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; ARTHRITIS; ARTICLE; BLAU SYNDROME; BLOOD SAMPLING; CHILD; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; GENE; GENE MUTATION; HUMAN; MALE; NOD2 GENE; ONSET AGE; PEDIGREE ANALYSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RASH; SYMPTOM; SYNDROME DELINEATION; TREATMENT OUTCOME; UVEITIS;

ADOLESCENT; ADULT; ANTIRHEUMATIC AGENTS; ARTHRITIS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; FEMALE; GRANULOMA; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1; MALE; MIDDLE AGED; MUTATION, MISSENSE; NOD2 SIGNALING ADAPTOR PROTEIN; PEDIGREE; RECURRENCE; SPAIN; SYNDROME; UVEITIS;

EID: 36048981805     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.22966     Document Type: Article

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