Enhanced interleukin-1 activity contributes to exercise intolerance in patients with systolic heart failure

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  van Tassell, Benjamin W ^a   Arena, Ross A ^b   Toldo, Stefano ^a   Mezzaroma, Eleonora ^a   Azam, Tania ^c   Seropian, Ignacio M ^a   Shah, Keyur ^a   Canada, Justin ^a   Voelkel, Norbert F ^a   Dinarello, Charles A ^c   Abbate, Antonio ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 1BETA; ISOPRENALINE; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; AUTACOID; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CYTOKINE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RECOMBINANT PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREATHING MECHANICS; CARDIOPULMONARY EXERCISE TEST; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEART LEFT VENTRICLE FAILURE; HUMAN; INFLAMMATION; MALE; MOUSE; NONHUMAN; OPEN STUDY; PILOT STUDY; SIGNAL TRANSDUCTION; SYSTOLIC HEART FAILURE; VENOUS OXYGEN TENSION; ANIMAL; BLOOD; CLINICAL TRIAL; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; EXERCISE TEST; EXERCISE TOLERANCE; HEART CONTRACTION; HEART LEFT VENTRICLE FUNCTION; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; MIDDLE AGED; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; PHYSIOLOGY;

MUS;

ADULT; ANIMALS; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CYTOKINES; DISEASE MODELS, ANIMAL; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; HEART FAILURE, SYSTOLIC; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; MALE; MICE; MICE, INBRED ICR; MIDDLE AGED; MYOCARDIAL CONTRACTION; OXYGEN CONSUMPTION; RECOMBINANT PROTEINS; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84858405983     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033438     Document Type: Article

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