A phase II, multicenter, open-label study evaluating dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features

Arthritis and Rheumatism

Volumn 64, Issue 2, 2012, Pages 557-567

  Ruperto, Nicolino ^a   Quartier, Pierre ^b   Wulffraat, Nico ^c   Woo, Patricia ^d   Ravelli, Angelo ^a   Mouy, Richard ^b   Bader Meunier, Brigitte ^b   Vastert, Sebastiaan J ^c   Noseda, Emanuele ^e   D'Ambrosio, Daniele ^e   Lecot, Jean ^e   Chakraborty, Abhijit ^e   Martini, Alberto ^a   Chioato, Andrea ^e  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CANAKINUMAB; CORTICOSTEROID; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ABDOMINAL PAIN; ADULT; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; CONSTIPATION; COUGHING; DIARRHEA; DOSE RESPONSE; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ERYTHEMA; FEMALE; FEVER; GASTROENTERITIS; HEADACHE; HUMAN; INJECTION SITE REACTION; JUVENILE RHEUMATOID ARTHRITIS; MALE; MULTICENTER STUDY; NAUSEA; PHARYNGEAL ERYTHEMA; PHARYNGITIS; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RELAPSE; RHINITIS; RHINOPHARYNGITIS; TONSILLITIS; TREATMENT RESPONSE; UPPER RESPIRATORY TRACT INFECTION; URTICARIA; VOMITING;

ADOLESCENT; ANTIBODIES, MONOCLONAL; ANTIRHEUMATIC AGENTS; ARTHRITIS, JUVENILE RHEUMATOID; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INTERLEUKIN-1BETA; MALE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84856370186     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.33342     Document Type: Article

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