NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1β processing via the NLRP1 inflammasome

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 8, 2013, Pages 2952-2956

  Levandowski, Cecilia B ^a   Mailloux, Christina M ^a   Ferrara, Tracey M ^a   Gowan, Katherine ^a   Ben, Songtao ^a   Jin, Ying ^a,b   McFann, Kimberly K ^c   Holland, Paulene J ^a   Fain, Pamela R ^a,b   Dinarello, Charles A ^a   Spritz, Richard A ^a,b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b Children's Hospital Colorado   (United States)

^c Global Health and Health Disparities   (United States)

Author keywords

Cytokine; DNA sequencing; Interleukin 1beta

Indexed keywords

INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LEUCINE RICH REPEAT PROTEIN 1; PROTEIN SERINE THREONINE KINASE; RNA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG;

ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; DNA SEQUENCE; ENZYME RELEASE; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC RISK; HAPLOTYPE; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; MONOCYTE; PREDICTION; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN STABILITY; RHEUMATOID ARTHRITIS; VITILIGO;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOPTOSIS REGULATORY PROTEINS; AUTOIMMUNITY; HAPLOTYPES; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; MONOCYTES; VITILIGO;

EID: 84874249068     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1222808110     Document Type: Article

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